isoproterenol has been researched along with Chagas Cardiomyopathy in 6 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In previous work, we have shown that the chronic administration of verapamil, a calcium channel blocker, ameliorated the mortality, pathology, and biochemical alterations associated with acute murine Chagas' disease." | 5.28 | Effect of verapamil on the development of chronic experimental Chagas' disease. ( Bilezikian, JP; Factor, SM; Morris, SA; Tanowitz, HB; Weiss, LM; Wittner, M, 1989) |
| "In previous work, we have shown that the chronic administration of verapamil, a calcium channel blocker, ameliorated the mortality, pathology, and biochemical alterations associated with acute murine Chagas' disease." | 1.28 | Effect of verapamil on the development of chronic experimental Chagas' disease. ( Bilezikian, JP; Factor, SM; Morris, SA; Tanowitz, HB; Weiss, LM; Wittner, M, 1989) |
| " Displacement of the dose-response curve to IP to the right occurred in the acute phase group." | 1.27 | Trypanosoma cruzi (CL strain) infection in mice changes the chronotropic effect of isoproterenol in vitro. ( Pereira, FE; Pires, JG, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haberland, A | 1 |
| Wallukat, G | 1 |
| Dahmen, C | 1 |
| Kage, A | 1 |
| Schimke, I | 1 |
| Hernández, CC | 1 |
| Barcellos, LC | 1 |
| Giménez, LE | 1 |
| Cabarcas, RA | 1 |
| Garcia, S | 1 |
| Pedrosa, RC | 1 |
| Nascimento, JH | 1 |
| Kurtenbach, E | 1 |
| Masuda, MO | 1 |
| Campos de Carvalho, AC | 1 |
| Bergdolt, BA | 1 |
| Tanowitz, HB | 2 |
| Wittner, M | 3 |
| Morris, SA | 3 |
| Bilezikian, JP | 3 |
| Moreno, AP | 1 |
| Spray, DC | 1 |
| Barr, S | 1 |
| Weiss, L | 1 |
| Tanowitz, H | 1 |
| Weiss, LM | 1 |
| Factor, SM | 1 |
| Pires, JG | 1 |
| Pereira, FE | 1 |
6 other studies available for isoproterenol and Chagas Cardiomyopathy
| Article | Year |
|---|---|
Aptamer neutralization of beta1-adrenoceptor autoantibodies isolated from patients with cardiomyopathies.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Animals; Antibody Speci | 2011 |
Human chagasic IgGs bind to cardiac muscarinic receptors and impair L-type Ca2+ currents.
Topics: Animals; Antibodies; Atropine; Calcium Channels, L-Type; Case-Control Studies; Chagas Cardiomyopathy | 2003 |
Trypanosoma cruzi: effects of infection on receptor-mediated chronotropy and Ca2+ mobilization in rat cardiac myocytes.
Topics: Animals; Animals, Newborn; Calcium; Cells, Cultured; Chagas Cardiomyopathy; Guanylyl Imidodiphosphat | 1994 |
Myocardial beta-adrenergic adenylate cyclase complex in a canine model of chagasic cardiomyopathy.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Binding, Competitive; Chagas Cardiomyopath | 1991 |
Effect of verapamil on the development of chronic experimental Chagas' disease.
Topics: Adenylyl Cyclases; Animals; Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Disease Models, | 1989 |
Trypanosoma cruzi (CL strain) infection in mice changes the chronotropic effect of isoproterenol in vitro.
Topics: Animals; Chagas Cardiomyopathy; Dose-Response Relationship, Drug; Heart Atria; Heart Rate; In Vitro | 1987 |