Page last updated: 2024-10-29

isoproterenol and Cardiovascular Stroke

isoproterenol has been researched along with Cardiovascular Stroke in 1089 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Research Excerpts

ExcerptRelevanceReference
" Isoproterenol (ISP)-induced myocardial ischemia is a classical model to screen the cardioprotective effects of various pharmacological interventions."8.98Isoproterenol-induced cardiac ischemia and fibrosis: Plant-based approaches for intervention. ( Allawadhi, P; Godugu, C; Khurana, A; Kumari, P; Sayed, N, 2018)
"Myocardial infarction was induced by injecting subcutaneous isoproterenol (5 mg/kg once for 7 consecutive days) to establish an experimental heart failure model."8.31Comparative Efficacy of Levosimendan, Ramipril, and Sacubitril/ Valsartan in Isoproterenol-induced Experimental Heart Failure: A Hemodynamic and Molecular Approach. ( Afzal, O; Akhtar, MS; Altamimi, A; Hassan, MZ; Hassan, Q; Mohammad, AAS; Sharma, AK; Tabassum, F, 2023)
" However, researchers recently investigated the potential cardioprotective effects of taraxerol utilizing an isoproterenol (ISO)-induced cardiotoxicity model among Sprague Dawley rats."8.31Effects of Taraxerol on Oxidative and Inflammatory Mediators in Isoproterenol-Induced Cardiotoxicity in an Animal Model. ( Alam, A; Alkholifi, FK; Aodah, AH; Devi, S; Foudah, AI; Yusufoglu, HS, 2023)
" The objective of this study was to analyze the effect of essential oil of Alpinia zerumbet (EOAz) on cardiovascular and autonomic function in rats with isoproterenol-induced myocardial infarction."8.31Effect of essential oil of Alpinia zerumbet on cardiovascular and autonomic function in rats with isoproterenol induced acute myocardial infarction. ( Costa, PPC; Fechine, FV; Holanda, TM; Ingram, C; Maia, PHF; Moraes Filho, MO; Moraes, MEA; Rocha, DG; Silveira, JAM, 2023)
" The present study aimed to investigate the effect of TQ on apoptotic parameters and MMP-9 expression in isoproterenol (ISP)-induced myocardial infarction (MI)."8.12Thymoquinone attenuates isoproterenol-induced myocardial infarction by inhibiting cytochrome C and matrix metalloproteinase-9 expression. ( Awad, A; Badr, AM; El-Bakly, WM; El-Demerdash, E; Medhet, M, 2022)
"The current study investigated the prophylactic effect of ethyl pyruvate (EP) in Isoproterenol (ISO) - induced myocardial infarction (MI)."8.12Ethyl pyruvate attenuates isoproterenol-induced myocardial infarction in rats: Insight to TNF-α-mediated apoptotic and necroptotic signaling interplay. ( Ahmed, AAE; Al-Botaty, BM; Elkhoely, A; K El-Sayed, E, 2022)
"The present study investigated the cardioprotection of Indole-3-carbinol on isoproterenol (ISO)-induced myocardial infarction in Wistar rats."8.12Indole-3-carbinol ameliorated the isoproterenol-induced myocardial infarction via multimodal mechanisms in Wistar rats. ( Krishnamurthy, S; Ramakrishna, K, 2022)
" No studies were conducted earlier on the effects of (-) epicatechin (EC) on tachycardia, cardiac hypertrophy, and inflammation in MI."8.12Preventive effects of (-) epicatechin on tachycardia, cardiac hypertrophy, and nuclear factor- κB inflammatory signaling pathway in isoproterenol-induced myocardial infarcted rats. ( Ponnian, SMP, 2022)
"Anethole may retain a cardio-protective potential by controlling myocardial oxidative stress (through Nrf2 pathway) and diminishing inflammation and apoptosis via the TLR4/MYD88 pathway."8.12Anethole's effects against myocardial infarction: The role of TLR4/NFκB and Nrf2/HO1 pathways. ( Mohamed, ME; Younis, NS, 2022)
" Rats were induced MI by isoproterenol (100 mg/kg body weight) and then treated with valencene and cardiac sensitive markers, cardiac hypertrophy, oxidative stress, markers of inflammation, nuclear factor- κB inflammatory pathway, and myocardial infarct size was estimated/determined."8.12Valencene post-treatment exhibits cardioprotection via inhibiting cardiac hypertrophy, oxidative stress, nuclear factor- κB inflammatory pathway, and myocardial infarct size in isoproterenol-induced myocardial infarcted rats; A molecular study. ( Berlin Grace, VM; Shervin Prince, S; Stanely Mainzen Prince, P, 2022)
"This study has explored the fact that geraniol prevents isoproterenol (ISO)-induced oxidative stress and inflammation-mediated myocardial infarction (MI) through enhanced expression of peroxiredoxin-1 (Prdx-1) in experimental animal models."8.12Geraniol enhances peroxiredoxin-1, and prevents isoproterenol-induced oxidative stress and inflammation associated with myocardial infarction in experimental animal models. ( Balupillai, A; David, E; Ranganathan, B; Saravanan, K; Wan, J; Zou, G, 2022)
" The present study was designed to investigate the cardioprotective effects of a newly synthesised coumarin, symbolised as 5,6-PhSHC, against cardiac remodelling process in isoproterenol (ISO) induced myocardial infarction (MI) in male Wistar rats by evaluating haematological, biochemical and cardiac biomarkers."8.12A novel synthetised sulphonylhydrazone coumarin (E)-4-methyl-N'-(1-(3-oxo-3H-benzo[f]chromen-2- yl)ethylidene)benzenesulphonohydrazide protect against isoproterenol-induced myocardial infarction in rats by attenuating oxidative damage, biological changes ( Abid, M; Abid, S; Allouche, N; Ammar, H; Baaziz, I; Elmufti, A; Feriani, A; Ghazouani, L; Hajji, R; Khdhiri, E; Mnafgui, K; Ramazani, A; Tlili, N; Zarei, A, 2022)
"Earlier studies reported that long-term treatment with thymoquinone (TQ) at a high dose (20 mg/kg) exerts a cardioprotective effect against isoproterenol (ISO)-triggered myocardial infarction (MI) in rats."8.12Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation. ( Agrawal, Y; Goyal, SN; Nagoor Meeran, MF; Nakhate, KT; Ojha, S; Patil, CR; Rathod, S; Sherikar, A, 2022)
" The present study evaluated the effectiveness of rosmarinic acid (RA) against myocardial infarction (MI) in comorbid depression induced by maternal separation in rats."8.12Evaluation of rosmarinic acid against myocardial infarction in maternally separated rats. ( Bhattacharjee, A; Nayak, PK; Shivavedi, N; Verma, H, 2022)
"In the present study, we assessed the therapeutic potential of Biochanin-A (BCA) (10 mg/kg BW/day) pretreatment for 30 days on lipid metabolic abnormalities, proinflammatory cytokines and matrix metalloproteinase expression in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."8.12Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats. ( Chandrasekaran, P; Jansy Isabella, RAR; Ponmurugan, P; Sangeethadevi, G; Saravanan, G; Sengottuvelu, S; V V, SU; Vadivukkarasi, S, 2022)
" The study was conducted to examine the ability of amniotic membrane mesenchymal stem cells (AMSCs) for protection against isoproterenol (ISO)-induced myocardial injury and attempted to show the possible mechanisms by which AMSCs that can be linked to inhibition of inflammation by targeting inflammatory MAPK/NF-κB pathway."8.12Human amniotic membrane mesenchymal stem cells exert cardioprotective effects against isoproterenol (ISO)-induced myocardial injury through suppression of inflammation and modulation of inflammatory MAPK/NF-κB pathway. ( Aboutaleb, N; Naseroleslami, M, 2022)
"The objective of the present paper is to formulate nanostructured lipid carriers (NLCs) of a calcium channel blocker, isradipine, to enhance its oral bioavailability and prolong its antihypertensive effect apart from evaluating efficacy of the formulation in isoproterenol induced myocardial infarction in rats."8.12Nanostructured lipid carriers of isradipine for effective management of hypertension and isoproterenol induced myocardial infarction. ( Alam, T; Ali, J; Ansari, MA; Baboota, S, 2022)
"The study explored the cardioprotective role of the methanolic leaf extract of Nelumbo nucifera and nuciferine against isoproterenol-induced myocardial infarction (MI) in Wistar rats."8.12Nuciferine from Nelumbo nucifera Gaertn. attenuates isoproterenol-induced myocardial infarction in Wistar rats. ( HarishKumar, R; Selvaraj, CI, 2022)
" Ten male NMRI mice were randomly divided into two groups: (1) control (healthy mice) and (2) myocardial infarction (MI)-induced model group (Isoproterenol/subcutaneously injection/single dose of 85 mg/kg)."8.02Cardiac aorta-derived extracellular matrix scaffold enhances critical mediators of angiogenesis in isoproterenol-induced myocardial infarction mice. ( Abdolmaleki, Z; Beheshtiha, SHS; Hosseinabadi, M, 2021)
" The current study has been designed to ascertain their effectiveness against Isoproterenol (ISO)-induced myocardial infarction (MI)."8.02Pharmacological evaluation of Vitis vinifera and Zingiber zerumbet on electrocardiographic, biochemical alterations and antioxidant status in isoproterenol-induced myocardial infarction in rats. ( Faisal, N; Hanif, M; Hassan Mehmood, M; Munir, I; Naseer, D, 2021)
"The present study demonstrated the protective effects of arbutin (ARB) on hyperlipidemia, mitochondrial, and lysosomal membrane damage and on the DNA damage in rats with isoproterenol (ISO)-induced myocardial infarction (MI)."8.02Arbutin prevents alterations in mitochondrial and lysosomal enzymes in isoproterenol-induced myocardial infarction: An in vivo study. ( Asaikumar, L; Sivasangari, S; Vennila, L, 2021)
"This study aimed to investigate the antihyperlipidemic and anti-inflammatory effect of zingiberene (ZBN) on isoproterenol-(ISO) induced myocardial infarction in rats."8.02Anti-inflammatory and anti-apoptotic effect of zingiberene on isoproterenol-induced myocardial infarction in experimental animals. ( Govindasamy, K; Li, J; Thangaiyan, R; Wei, J, 2021)
" This study investigated the therapeutic benefit of adding rosuvastatin to low-dose carvedilol in protection against myocardial infarction (MI)."8.02Rosuvastatin and low-dose carvedilol combination protects against isoprenaline-induced myocardial infarction in rats: Role of PI3K/Akt/Nrf2/HO-1 signalling. ( Awad, AS; Baraka, SA; El-Demerdash, E; El-Naga, RN; Elsherbini, DA; Tolba, MF, 2021)
"As rats develop myocardial infarction (MI) like lesions when injected with large doses of isoproterenol (ISO), this investigation was designed to evaluate the dose-dependent effects of thymoquinone (TQ) on ISO-induced myocardial injury in rats."8.02Thymoquinone dose-dependently attenuates myocardial injury induced by isoproterenol in rats via integrated modulations of oxidative stress, inflammation, apoptosis, autophagy, and fibrosis. ( Elhadidy, WF; Farag, MM; Khalifa, AA; Rashad, RM, 2021)
" In the present study, we report that wogonin nanoparticles (Wog np) protect Isoproterenol (ISO) induced Myocardial Infarction (MI) rats."7.96Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction by moderating oxidative stress and inflammation. ( Bei, W; Chen, N; Jing, L, 2020)
"The current study enumerates the beneficial role of sciadopitysin (SDN) against isoproternol (ISO)-induced myocardial infarction (MI) in rats."7.96Protective Effect of Sciadopitysin against Isoproternol-Induced Myocardial Infarction in Rats. ( Cai, Y; Li, Y, 2020)
"Our study is aimed at evaluating the effects of pretreatment with Poly(lactic-co-glycolic) acid nanoparticle loaded with resveratrol (RSV PLGA NPs) compared to conventional resveratrol (RSV) on isoproterenol (ISO) induced myocardial infarction (MI) in rats."7.96Protective role of poly(lactic-co-glycolic) acid nanoparticle loaded with resveratrol against isoproterenol-induced myocardial infarction. ( Hu, Y; Kumar, P; Mishra, A; Moktan, JB; Sreeharsha, N; Sun, L; Wang, L, 2020)
"This study determined the effect of Biochanin A (BCA) on isoproterenol (ISO) induced Myocardial Infarction (MI) in male Wistar rats."7.96Therapeutic Potential of Biochanin-A Against Isoproterenol-Induced Myocardial Infarction in Rats. ( Govindasami, S; Raveendran, N; Sasikumar, V; Uddandrao, VVS, 2020)
"HC), a novel potent synthesized coumarin, on isoproterenol- (ISO-) induced myocardial infarction (MI) in rats."7.96(E)-N'-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis. ( Abid, S; Allouche, N; Ammar, H; Elmufti, A; Feriani, A; Ghazouani, L; Hajji, R; Khdhiri, E; Mnafgui, K; Tir, M; Tlili, N, 2020)
"The present study was aimed to discover novel pyrazole-thiadiazole derivatives as potent NF-ĸB inhibitor and its cardioprotective effect against isoproterenol (ISO)-induced myocardial infarction (MI) in rats."7.96Design and Development of Novel Pyrazole-Thiadiazole Derivatives as NF-ĸB Inhibitor and Cardioprotective Effect against Isoproterenol Induced Myocardial Infarction in Sprague-Dawley Rats. ( Guo, Y; Wang, J; Wu, X; Zhang, Y, 2020)
" Long non-coding RNA myocardial infarction associated transcript (LncMIAT) is closely related to heart disease, and here, we were the first to discover that LncMIAT may act as an miR-144 sponge in isoproterenol-induced cardiac hypertrophy."7.96The Expression of microRNA in Adult Rat Heart with Isoproterenol-Induced Cardiac Hypertrophy. ( Bai, L; Chen, L; Fan, Y; Gan, M; Guo, Z; Hao, X; Jiang, D; Li, X; Shen, L; Tan, Y; Zhang, S; Zhu, L, 2020)
" In this study, we investigated the preventive effect of alpha-pinene (AP), a monoterpene, against isoproterenol (ISO)-induced myocardial infarction and inflammation in Wistar rats."7.96Protective effect of alpha-pinene against isoproterenol-induced myocardial infarction through NF-κB signaling pathway. ( Cao, M; Wang, G; Wang, H; Wang, K; Yang, Z; Zhang, B; Zhao, Y, 2020)
"This research was aimed to explore protective effects of allicin on rat model of myocardial infarction via JNK signaling pathway."7.96Protective Effects of Allicin on ISO-Induced Rat Model of Myocardial Infarction via JNK Signaling Pathway. ( Li, EZ; Li, XP; Liu, YF; Ma, L; Wei, LN; Xu, W; Zhao, J, 2020)
" In particular, compound 4i was found to be the most potent ACE inhibitor and was further studied for cardioprotective effects against isoproterenol (ISO)-induced myocardial infarction (MI) in rats."7.96Novel thiazole-pyrazolone hybrids as potent ACE inhibitors and their cardioprotective effect on isoproterenol-induced myocardial infarction. ( Su, G; Su, X; You, H, 2020)
"The aim of this study was to evaluate the anti-ischemic effects of SAC through inhibiting neprilysin in isoproterenol (ISO) induced myocardial infarction (MI) in Wistar albino rats."7.91Sacubitril and valsartan protect from experimental myocardial infarction by ameliorating oxidative damage in Wistar rats. ( Akhtar, M; Akhtar, MS; Hassan, MQ; Imran, M; Najmi, AK; Rahman, O, 2019)
"This study was designed to investigate efficacy of Narirutin rich fraction (NRF), obtained from grape fruit peel, in the treatment of isoproterenol induced myocardial infarction in rats."7.91Attenuation of isoproterenol-induced cardiotoxicity in rats by Narirutin rich fraction from grape fruit. ( Barve, K; Bhatt, LK; Shaikh, S, 2019)
" Then, isoproterenol solution was used for induction of myocardial infarction."7.91The protective impact of betaine on the tissue structure and renal function in isoproterenol-induced myocardial infarction in rat. ( Babaei, G; Ghartavol, MM; Gholizadeh-Ghaleh Aziz, S; Hassan Khadem Ansari, M; Hossein Farjah, G, 2019)
" The investigation was conducted to evaluate the cardioprotective efficacy of RPG in rats having acute myocardial infarction (MI) induced by isoproterenol (ISO)."7.91Cardioprotective Effect of Rhapontigenin in Isoproterenol-Induced Myocardial Infarction in a Rat Model. ( Fan, Y, 2019)
"This study was designed to delineate the effect of kaempferol (KF) on heart failure (HF) in diabetic rats."7.91The protective effect of kaempferol on heart via the regulation of Nrf2, NF-κβ, and PI3K/Akt/GSK-3β signaling pathways in isoproterenol-induced heart failure in diabetic rats. ( Geng, J; Guo, Z; Han, S; Wang, Y; Zhang, L, 2019)
"In the present study, the modulatory effect of ursolic acid (UA) on cardiac fibrosis and mitochondrial and lysosomal enzymes activity in isoproterenol-induced myocardial infarction (MI) in rats were examined."7.91Ursolic acid modulates MMPs, collagen-I, α-SMA, and TGF-β expression in isoproterenol-induced myocardial infarction in rats. ( Pugalendi, KV; Radhiga, T; Senthil, S; Sundaresan, A, 2019)
" The present study aimed to elucidate the potential cardioprotective effect provided by ranolazine during myocardial infarction in nondiabetic and diabetic male rats."7.91Cardioprotective effect of ranolazine in nondiabetic and diabetic male rats subjected to isoprenaline-induced acute myocardial infarction involves modulation of AMPK and inhibition of apoptosis. ( Ameen, AM; Tawfik, MK, 2019)
" Our study is aimed at evaluating the effects of pretreatment with curcumin nanoparticles (CCNP) compared to conventional curcumin (CC) on isoproterenol (ISO) induced myocardial infarction (MI) in rats."7.91Effects of Curcumin Nanoparticles in Isoproterenol-Induced Myocardial Infarction. ( Boarescu, PM; Bocșan, IC; Bolboacă, SD; Bulboacă, AE; Chirilă, I; Gheban, D; Pop, RM, 2019)
"Cardioprotective potential of aliskiren against isoproterenol-induced myocardial infarction was evaluated in this study."7.88Renin Inhibition by Aliskiren Protects Rats Against Isoproterenol Induced Myocardial Infarction. ( Akhtar, M; Hassan, MQ; Khan, V; Najmi, AK, 2018)
" Myocardial infarction was induced in Wistar rats via isoproterenol injection in a dose of (85 mg/kg, subcutaneously, twice at an interval of 24 h)."7.88Novel Mesenchymal Stem Cell Strategy in Alleviating Toll-Like Receptor-4, p53 and Nrf2 Signaling in Isoproterenol-Induced Myocardial Infarction in Rat Model. ( Abdel-Megeed, RM; Kadry, MO, 2018)
"The cardioprotective role of raspberry ketone (RK) against isoproterenol (ISO)-induced myocardial infarction (MI) in rats was assessed."7.88Raspberry ketone protects against isoproterenol-induced myocardial infarction in rats. ( Ali, SM; Bhandari, U; Haque, SE; Khan, V; Sharma, S, 2018)
" This study evaluated the cardioprotective effect of rosuvastatin on isoproterenol-induced myocardial infarction injury in rats."7.88Cardioprotective effect of rosuvastatin against isoproterenol-induced myocardial infarction injury in rats. ( Cang, J; Guo, K; Hu, Y; Jin, L; Yu, Y; Zhuang, Y, 2018)
"To investigate the effects and mechanisms of catalpol on cardiac function in rats with isoproterenol (ISO)-induced myocardial infarction (MI)."7.88Catalpol pretreatment attenuates cardiac dysfunction following myocardial infarction in rats. ( Bi, F; Sun, Q; Xu, Y, 2018)
" The present study was directed to investigate the effect of ATV pre- and post-treatment in isoproterenol (ISO)-induced cardiotoxicity in rats."7.88Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation. ( Ahmed, LA; Attalla, DM; Khattab, MM; Zaki, HF, 2018)
"This study examined the effects of aliskiren (Ali) (direct renin inhibitor) on serum cardiac enzymes (LDH and CK-MB), electrocardiography (ECG) changes, myocardial oxidative stress markers (MDA, CAT, and GSH) and the expression of Bcl2, HO-1, and Nrf2 genes in isoproterenol (ISO)-induced myocardial infarction (MI)."7.88Effects of low dose of aliskiren on isoproterenol-induced acute myocardial infarction in rats. ( Bin-Jaliah, I; Eid, EA; Hussein, AM; Sakr, HF, 2018)
"The effect of α-bisabolol on hemodyanimcs, lipid peroxidation, and nonenzymatic antioxidants was evaluated in isoproterenol-induced myocardial infarction in rats."7.88Protective effects of α-bisabolol on altered hemodynamics, lipid peroxidation, and nonenzymatic antioxidants in isoproterenol-induced myocardial infarction: In vivo and in vitro evidences. ( Al-Taee, H; Azimullah, S; Laham, F; Meeran, MFN; Ojha, S, 2018)
"The present study was designed to investigate the protective effect of ferulic acid (FA) against isoproterenol (ISO)-induced cardiac toxicity in rats."7.88Cardioprotective role of FA against isoproterenol induced cardiac toxicity. ( Jain, PG; Mahajan, UB; Shinde, SD; Surana, SJ, 2018)
" This study was performed to investigate the effects of syrigaldehyde (SYD), a phytochemical against isoproterenol (ISO) induced cardiotoxicity model."7.88Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats. ( Akhtar, K; Mateen, S; Moin, S; Mubeena Mariyath, PM; Naeem, SS; Rizvi, W; Shahzad, S, 2018)
" Therefore, the current investigation was intended to evaluate the effect of malvidin against myocardial infarction induced by isoproterenol in the rats."7.85Cardioprotective Effects of Malvidin Against Isoproterenol-Induced Myocardial Infarction in Rats: A Mechanistic Study. ( Cheng, LX; Jiang, LL; Li, H; Peng, YD; Wan, SP; Wei, H; Zeng, QT, 2017)
"The present study investigated the protective effect of diethylcarbamazine in inhibiting nuclear factor (NF)-κB activation in isoproterenol‑induced acute myocardial infarction (AMI) rats through the poly ADP ribose polymerase (PARP) pathway."7.85Protective effect of diethylcarbamazine inhibits NF-κB activation in isoproterenol-induced acute myocardial infarction rat model through the PARP pathway. ( Jia, G; Liu, X; Zao, M, 2017)
", family Arecaceae) on isoproterenol-induced myocardial infarction (MI) in rats."7.85Cardiopreventive effect of ethanolic extract of Date Palm Pollen against isoproterenol induced myocardial infarction in rats through the inhibition of the angiotensin-converting enzyme. ( Abid, L; Ayadi, F; Belbahri, L; Ben Amar, R; Ben Mefteh, F; Daoud, A; ElFeki, A; Gharsallah, N; Jmal, S; Kadri, A; Mnafgui, K; Rateb, ME; Turki, M, 2017)
"The present study was designed to evaluate the cardioprotective effects of nesfatin-1, a novel peptide with anorexigenic properties, in rats with isoproterenol (ISO)-induced myocardial infarction (MI), and to further investigate the role of Akt/GSK-3β signaling pathway in the protective effect of nesfatin-1."7.85Cardioprotective effect of nesfatin-1 against isoproterenol-induced myocardial infarction in rats: Role of the Akt/GSK-3β pathway. ( Adiguzel, D; Barutcigil, A; Celik-Ozenci, C; Dalaklioglu, S; Kuscu, N; Ozdem, S; Tasatargil, A, 2017)
" macroptera peel and pulp against isoproterenol (ISO)-induced myocardial infarction (MI) in rats."7.85Protective effects of ethanolic peel and pulp extracts of Citrus macroptera fruit against isoproterenol-induced myocardial infarction in rats. ( Afroz, R; Das, S; Gan, SH; Hossain, MS; Hossen, MS; Ibrahim Khalil, M; Islam, MA; Paul, S; Saha, M; Tanvir, EM, 2017)
"The present study aimed to investigate the cardioprotective effect of hydroxytyrosol (HT) against isoproterenol-induced myocardial infarction in rats."7.83Protective Effect of Hydroxytyrosol Against Cardiac Remodeling After Isoproterenol-Induced Myocardial Infarction in Rat. ( Allouche, N; Derbali, F; Elfeki, A; Ellefi, H; Gharsallah, N; Hajji, R; Khlif, I; Kraiem, F; Mnafgui, K, 2016)
"This study aimed to evaluate the antithrombotic, anti-inflammatory and anti-cardiac remodeling properties of eugenol in isoproterenol-induced myocardial infarction in rats."7.83Anti-inflammatory, Antithrombotic and Cardiac Remodeling Preventive Effects of Eugenol in Isoproterenol-Induced Myocardial Infarction in Wistar Rat. ( Allouche, N; Derbali, F; Ellefi, H; Gammoudi, A; Gharsallah, N; Hajji, R; Kadri, A; Khabbabi, G; Mnafgui, K, 2016)
"The current study investigated the combinatorial effect of pravastatin (PRAV) and bone marrow mononuclear cells (BM-MNC) on acute myocardial infarction (AMI) induced experimentally in rats."7.83Bone marrow mononuclear cells enhance anti-inflammatory effects of pravastatin against isoproterenol-induced myocardial infarction in rats. ( El-Desouky, KI; El-Mahdy, N; El-Sayad, M; Salem, ML; Zaghow, N, 2016)
"In the present study, we investigated whether combination therapy of low-dose benidipine with the potent free radical scavenger edaravone has a cardioprotective effect against isoproterenol (ISO)-induced myocardial infarction (MI) in Wistar rats."7.83Edaravone, a potent free radical scavenger and a calcium channel blocker attenuate isoproterenol induced myocardial infarction by suppressing oxidative stress, apoptotic signaling and ultrastructural damage. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2016)
"This study evaluates the protective effects of 7-hydroxycoumarin (7-HC) on dyslipidemia and cardiac hypertrophy in isoproterenol (ISO) induced myocardial infarction (MI) in rats."7.83Protective Effects of 7-Hydroxycoumarin on Dyslipidemia and Cardiac Hypertrophy in Isoproterenol-Induced Myocardial Infarction in Rats. ( Jagadeesh, GS; Nagoor Meeran, MF; Selvaraj, P, 2016)
"Subcutaneous injection of isoproterenol (85 mg/kg) on last 2 consecutive days in per se group and 7 days treatment of different groups at 24 h interval induced myocardial infarction in Wistar rats."7.83Histamine H3 Receptor Agonist Imetit Attenuated Isoproterenol Induced Renin Angiotensin System and Sympathetic Nervous System Overactivity in Myocardial Infarction of Rats. ( Akhtar, M; Hass, C; Khanam, R; Najmi, AK; Panda, BP, 2016)
"The present study investigates the cardioprotective activity of the Macrotyloma uniflorum seed extract (MUSE) and its phenolic acids (p-coumaric acid and ferulic acid) in isoproterenol (ISO)-induced myocardial infarction in rats."7.83Dietary Phenolic Acids of Macrotyloma uniflorum (Horse Gram) Protect the Rat Heart Against Isoproterenol-Induced Myocardial Infarction. ( Laddha, A; Nandave, M; Panda, V; Srinath, S, 2016)
" This work investigated the protective effect of pioglitazone on myocardial infarction (MI) in non-diabetic and diabetic rats, focusing on its role on advanced glycated endproducts (AGEs) and cardiac apoptotic machinery."7.83Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis. ( Farag, NE; Khodeer, DM; Moustafa, YM; Zaitone, SA, 2016)
" This study investigated the combined effect of low doses of fenofibrate and rosuvastatin in isoproterenol-induced experimental myocardial infarction."7.83Chronic oral administration of low-dose combination of fenofibrate and rosuvastatin protects the rat heart against experimentally induced acute myocardial infarction. ( Balakumar, P; Garg, M; Kalra, S; Khanna, D, 2016)
"The present study was designed to investigate the cardioprotective effects of Sundarban honey (SH) in rats with isoproterenol- (ISO-) induced myocardial infarction."7.83Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats. ( Afroz, R; Alam, N; Gan, SH; Hossain, MS; Karim, N; Khalil, MI; Tanvir, EM, 2016)
" In this paper, the mediation of XKS on the isoproterenol (ISO)-induced myocardial infarction (MI) rat were evaluated based on a tissue-targeted metabonomics in vitro/vivo."7.83Standardized Chinese Formula Xin-Ke-Shu inhibits the myocardium Ca(2+) overloading and metabolic alternations in isoproterenol-induced myocardial infarction rats. ( Chang, X; Jia, HM; Liu, YT; Zhou, C; Zou, ZM, 2016)
"In this study, the ability of KMP to protect heart against isoproterenol (ISO) induced oxidative stress and myocardial infarction was evaluated."7.83Kampeferol protects against oxidative stress and apoptotic damage in experimental model of isoproterenol-induced cardiac toxicity in rats. ( Arya, DS; Bhatia, J; Gamad, N; Goyal, SN; Malhotra, RK; Malik, S; Suchal, K, 2016)
"The effects of benidipine on oxidative stress and myocardial apoptosis were assessed in isoproterenol (ISO)-induced myocardial infarction (MI) in wistar rats."7.81Benidipine prevents oxidative stress, inflammatory changes and apoptosis related myofibril damage in isoproterenol-induced myocardial infarction in rats. ( Akhtar, M; Akhtar, MS; Ali, J; Ansari, SH; Haque, SE; Hassan, MQ; Najmi, AK, 2015)
" Therefore because oxidative stress plays a significant role in the pathophysiology of myocardial infarction (MI), the aim of our study was to investigate whether hydrogen-rich saline has cardioprotective effects against isoproterenol-induced MI in rats."7.81Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats. ( Han, JJ; Jing, L; Qin, SC; Sun, XJ; Wang, Y; Zhao, B; Zhao, XM, 2015)
"This study was aimed to evaluate the preventive role of phytic acid on lysosomal enzymes in isoproterenol (ISO)-induced myocardial infarction (MI) in male Wistar rats."7.81Preventive effect of phytic acid on lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats. ( Brindha, E; Rajasekapandiyan, M, 2015)
" alata (LPva) in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."7.81Protective effects of Labisia pumila var. alata on biochemical and histopathological alterations of cardiac muscle cells in isoproterenol-induced myocardial infarction rats. ( Amran, AZ; Dianita, R; Jalil, J; Jantan, I, 2015)
"The present study was designed to evaluate the cardioprotective potential of edaravone on oxidative stress, anti-apoptotic, anti-inflammatory and ultrastructure findings in isoproterenol (ISO) induced myocardial infarction (MI) in rats."7.81Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2015)
"The present study was designed to evaluate the cardioprotective effect of Tunisian flaxseed oil (Linum usitatissimum) against isoproterenol-induced myocardial infarction in rats by studying hypertensive and cardiac damage markers especially electrocardiographic changes and troponin T serum level."7.81Cardioprotective effect of linseed oil against isoproterenol-induced myocardial infarction in Wistar rats: a biochemical and electrocardiographic study. ( Affes, M; Allouche, N; Derbali, A; Derbali, F; El Feki, A; Gharsallah, N; Hajji, R; Mnafgui, K, 2015)
"Oleuropein offers high preventive effects from cardiac remodeling process in rats with acute myocardial infarction."7.81Preventive effects of oleuropein against cardiac remodeling after myocardial infarction in Wistar rat through inhibiting angiotensin-converting enzyme activity. ( Allouche, N; Derbali, F; Elfeki, A; Ellefi, H; Gharsallah, N; Hajji, R; Halabalaki, M; Khlif, I; Kraiem, F; Michel, T; Mnafgui, K; Skaltsounis, AL, 2015)
"The aim of the present study was to investigate the cardioprotective effects of Timosaponin B II (TB), a main bioactive constituent from Anemarrhenae asphodeloides Bge, on an isoproterenol (ISO)-induced myocardial infarction model in rats and explore its underlying mechanisms."7.81Cardioprotective effects of timosaponin B II from Anemarrhenae asphodeloides Bge on isoproterenol-induced myocardial infarction in rats. ( Chen, JJ; Deng, XY; Fu, Q; Li, HY; Ma, SP; Ma, ZQ, 2015)
" The current study investigated the effect of cardamom on hemodynamic, biochemical, histopathological and ultrastructural changes in isoproterenol (ISO)-induced myocardial infarction."7.81Protective Effects of Cardamom in Isoproterenol-Induced Myocardial Infarction in Rats. ( Agrawal, YO; Arya, DS; Goyal, SN; Kumari, S; Mahajan, UB; Ojha, S; Patil, CR; Sharma, C, 2015)
" In this study, we investigated whether baicalin ameliorates isoproterenol-induced acute myocardial infarction and its mechanism."7.81Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat. ( Chen, H; Ruan, H; Wang, J; Xu, Y; Zhao, W, 2015)
"Myocardial infarction (MI) was induced by subcutaneous injection of isoproterenol (ISO) to investigate the effect of ISO on Coenzyme Q10 (CoQ10) content of myocardium and subsequent effects on lipid peroxidation, electrocardiogram pattern and hemodynamic parameters of the rat's heart."7.80Reduction of coenzyme q10 content: a possible effect of isoproterenol on heart failure and myocardial infarction in rat. ( Andalib, S; Garjani, A; Ghanbarzadeh, S; Khorrami, A, 2014)
" The aim of the present study was to investigate the effects of OxLDL on electrocardiogram and hemodynamic parameters of rat's heart in isoproterenol (ISO)-induced myocardial infarction (MI) model."7.80Effects of LDL and oxidized LDL on cardiac function in isoproterenol-induced myocardial infarction in rat. ( Andalib, S; Arami, S; Garjani, A; Ghanbarzadeh, S; Khorrami, A; Maleki-Dizaji, N; Ziaee, M, 2014)
"Acute treatment with metformin has a protective effect in myocardial infarction by suppression of inflammatory responses due to activation of AMP-activated protein kinase (AMPK)."7.80Chronic treatment with metformin suppresses toll-like receptor 4 signaling and attenuates left ventricular dysfunction following myocardial infarction. ( Clanachan, AS; Garjani, A; Ghazi-Khansari, M; Maleki-Dizaji, N; Rameshrad, M; Soraya, H, 2014)
"Rats were injected with isoproterenol (ISO; 110 mg/kg, ip, 2 doses, 24 h interval) to induce acute myocardial infarction (AMI) and were sacrificed 6 and 24 h after the last ISO injection."7.80Effects of carnosine on prooxidant-antioxidant status in heart tissue, plasma and erythrocytes of rats with isoproterenol-induced myocardial infarction. ( Develi, S; Doğru-Abbasoğlu, S; Evran, B; Kalaz, EB; Karpuzoğlu, H; Olgaç, V; Soluk-Tekkeşin, M; Uysal, M, 2014)
" The other 32 rats were subjected to induction of hypercholesterolemia by high-fat diet for 3 weeks, followed by induction of AMI by subcutaneous injections of isoproterenol (85 mg/kg/day, for 2 days)."7.80Assessment of the prophylactic role of aspirin and/or clopidogrel on experimentally induced acute myocardial infarction in hypercholesterolemic rats. ( El-Hadidy, WF; Mannaa, HF; Mohamed, AR, 2014)
" Herein, we examined the effects of this peptide on isoproterenol (ISO)-induced cardiac remodeling and myocardial infarction (MI) injury."7.79The novel Mas agonist, CGEN-856S, attenuates isoproterenol-induced cardiac remodeling and myocardial infarction injury in rats. ( Almeida, AP; Beiman, M; Carvalho, MB; Cohen, Y; Cojocaru, G; Ferreira, AJ; Ianzer, D; Marques, FD; Peluso, AA; Rotman, G; Santos, RA; Savergnini, SQ; Silva, GA, 2013)
"The present study was designed to evaluate the cardioprotective potential of lycopene (LCP) against isoproterenol (ISP)-induced myocardial infarction (MI), by assessing hemodynamic, biochemical and histopathological parameters."7.79Cardioprotective effect of lycopene against isoproterenol-induced myocardial infarction in rats. ( Arora, S; Arya, DS; Goyal, S; Kumari, S; Ojha, S; Sharma, C, 2013)
" This study aims to evaluate the protective effects of sinapic acid on cardiac hypertrophy, dyslipidaemia and alterations in lipoproteins and electrocardiogram in isoproterenol-induced myocardial infarcted rats."7.79Protective effects of sinapic acid on cardiac hypertrophy, dyslipidaemia and altered electrocardiogram in isoproterenol-induced myocardial infarcted rats. ( Mainzen Prince, PS; Roy, SJ, 2013)
" In the present study, we evaluated the effects of metformin on cardiac function, hemodynamic parameters, and histopathological changes in isoproterenol-induced myocardial infarction (MI)."7.78Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats. ( Garjani, A; Khorrami, A; Maleki-Dizaji, N; Soraya, H, 2012)
"Vitamin A is beneficial in counteracting free radical damage, therefore the present study is designed to investigate the effect of vitamin A against isoproterenol-induced myocardial infarction in rats."7.78Cardio protective effect of vitamin A against isoproterenol-induced myocardial infarction. ( Pipaliya, H; Vaghasiya, J, 2012)
"To assess the protective effects of lycopene on electrocardiographic, hemodynamic, biochemical and apoptotic changes in isoproterenol induced myocardial infarction."7.78Tomato lycopene attenuates myocardial infarction induced by isoproterenol: electrocardiographic, biochemical and anti-apoptotic study. ( Aman, U; Balaraman, R; Vaibhav, P, 2012)
" We examined the effect of Se on LTB(4) synthesis during isoproterenol (ISP)-induced myocardial infarction (MI) in rats."7.78Impact of selenium on the leukotriene B4 synthesis pathway during isoproterenol-induced myocardial infarction in experimental rats. ( John, F; M, I; Panicker, S; Swathy, SS, 2012)
"The aim of this investigation was to evaluate the preventive role of morin, a flavonoid, on cardiac marker enzymes such as aspartate transaminase, lactate dehydrogenase, creatine kinase and creatine kinase-MB, membrane-bound enzymes such as sodium potassium-dependent adenosine triphosphatase, calcium-dependent adenosine triphosphatase and magnesium-dependent adenosine triphosphatase, and glycoproteins such as hexose, hexosamine, fucose and sialic acid in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."7.78Pretreatment with morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol-induced myocardial infarction in rats. ( Al-Numair, KS; Alsaif, MA; Chandramohan, G, 2012)
"The present study was designed to evaluate the protective effect of ursolic acid (UA) against isoproterenol-induced myocardial infarction."7.78Effect of ursolic acid treatment on apoptosis and DNA damage in isoproterenol-induced myocardial infarction. ( Ezhumalai, M; Pugalendi, KV; Radhiga, T; Rajamanickam, C; Sundaresan, A, 2012)
"The present investigation was to evaluate the antioxidant, biochemical profile and histological studies of qualitatively standardized ethanolic extract of Terminalia pallida fruits (TpFE) against isoproterenol-induced myocardial infarction in rats."7.78Cardioprotective effect of HPLC standardized ethanolic extract of Terminalia pallida fruits against isoproterenol-induced myocardial infarction in albino rats. ( Abdul Kareem, M; Lakshmi Devi, K; Rasool, SN; Saayi Krushna, G; Shaik, AH; Vikram Kumar Reddy, A, 2012)
"Myocardial infarction was produced in rats with 85 mgkg(-1) isoproterenol administered subcutaneously twice at an interval of 24 h."7.78Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats. ( Du, GH; Fang, LH; Gong, LL; Li, XX; Qin, HL; Sun, JL; Wang, SB, 2012)
" The present study reveals the protective role of ellagic acid in biochemical parameters including serum iron, plasma iron binding capacity, uric acid, glycoprotein, and electrolytes along with hematological parameters."7.78Protective efficacy of ellagic acid on glycoproteins, hematological parameters, biochemical changes, and electrolytes in myocardial infarcted rats. ( Kannan, MM; Quine, SD; Sangeetha, T, 2012)
" The activation of AMPK by metformin prevents cardiac remodeling after myocardial infarction (MI)."7.78Short-term treatment with metformin suppresses toll like receptors (TLRs) activity in isoproterenol-induced myocardial infarction in rat: are AMPK and TLRs connected? ( Banani, A; Farajnia, S; Garjani, A; Khani, S; Khorrami, A; Maleki-Dizaji, N; Rameshrad, M; Soraya, H, 2012)
"The cardioprotective potential of Inula racemosa root hydroalcoholic extract against isoproterenol-induced myocardial infarction was investigated in rats."7.77Effect of Inula racemosa root extract on cardiac function and oxidative stress against isoproterenol-induced myocardial infarction. ( Arya, DS; Bharti, S; Bhatia, J; Kumari, S; Ojha, S; Rani, N; Sharma, AK, 2011)
"Four groups of experimental rats were subcutaneously injected with sesamol (0, 1, 3, or 10 mg/kg) and then, 2 h later, intraperitoneally injected with isoproterenol (100 mg/kg 24 h apart on 2 consecutive days) to induce myocardial infarction."7.77Sesamol attenuates isoproterenol-induced acute myocardial infarction via inhibition of matrix metalloproteinase-2 and -9 expression in rats. ( Chang, CC; Chen, SY; Liu, MY; Mo, FE; Periasamy, S, 2011)
"We investigated the antioxidant preventive effect of betaine on isoprenaline-induced myocardial infarction in male albino rats."7.76Antioxidant defense of betaine against isoprenaline-induced myocardial infarction in rats. ( Anandan, R; AnbinEzhilan, R; Buddhan, S; Ganesan, B; Sivakumar, R, 2010)
" The aim of this study was to investigate the effect of selenium on NFκB activation in rats induced with myocardial infarction by isoproterenol (ISP)."7.76Impact of selenium on NFκB translocation in isoproterenol-induced myocardial infarction in rats. ( John, F; Madambath, I; Panicker, S; Swathy, SS, 2010)
"This study was designed to investigate the cardioprotective effect of sesamol on isoproterenol (ISO)-induced myocardial infarction in adult male albino Wistar rats."7.76Protective effect of sesamol against myocardial infarction caused by isoproterenol in Wistar rats. ( Pugalendi, KV; Vennila, L, 2010)
") juice (PJ) on heart weight, infarct size, plasma marker enzymes of cardiac damage, lipid peroxidation, endogenous enzymatic and non-enzymatic antioxidants, cardiac ATPases and histopathology of isoproterenol (IP)-induced cardiac necrosis (CN) in rats."7.76Pomegranate (Punica granatum L.) juice supplementation attenuates isoproterenol-induced cardiac necrosis in rats. ( Devkar, RV; Jadeja, RN; Patel, DK; Ramachandran, AV; Thounaojam, MC, 2010)
"The present study was designed to investigate the cardioprotective effect of melatonin against isoproterenol induced myocardial infarction in rats by studying myocyte injury markers, antioxidant defense system, serum and heart lipid profile, inflammatory markers, electrocardiographic and histopathological changes."7.76Cardioprotective effect of melatonin against isoproterenol induced myocardial infarction in rats: A biochemical, electrocardiographic and histoarchitectural evaluation. ( Balaraman, R; Patel, V; Upaganlawar, A; Zalawadia, R, 2010)
" Acute cardiogenic pulmonary edema was induced in C57BL/6J male mice by an increase in heart rate with continuous intravenous infusion of isoproterenol (ISP) (10 mg/kg/h) at 2 weeks after the creation of myocardial infarction by left coronary artery ligation."7.76Inhibition of secretory phospholipase A2 activity attenuates acute cardiogenic pulmonary edema induced by isoproterenol infusion in mice after myocardial infarction. ( Fujioka, D; Kawabata, K; Kobayashi, T; Kugiyama, K; Mishina, H; Nakamura, T; Obata, JE; Saito, Y; Watanabe, K; Watanabe, Y; Yano, T, 2010)
" In this study, cardioprotective activity of fucoidan extracted from Cladosiphon okamuranus was evaluated in isoproterenol induced myocardial infarction in rats."7.76Cardioprotective activity of Cladosiphon okamuranus fucoidan against isoproterenol induced myocardial infarction in rats. ( Pasanban, B; Rajendran, M; Rengasamy, R; Thomes, P, 2010)
" The purpose of the present study was to investigate the effects of CAPE on isoproterenol (ISO) -induced myocardial infarction."7.76Effects of caffeic acid phenethyl ester on isoproterenol-induced myocardial infarction in rats. ( Alçin, E; Aydin, M; Ilhan, S; Nacar, A; Oktar, S; Yönden, Z, 2010)
"The present study was undertaken to evaluate the preventive role of naringin on mitochondrial lipid peroxides, antioxidants and lipids in isoproterenol (ISO)-induced myocardial infarction (MI) in male Wistar rats."7.75Naringin ameliorates mitochondrial lipid peroxides, antioxidants and lipids in isoproterenol-induced myocardial infarction in Wistar rats. ( Prince, PS; Rajadurai, M, 2009)
"The present study was aimed to investigate the combined effects of green tea and vitamin E on heart weight, body weight, serum marker enzymes, lipid peroxidation, endogenous antioxidants and membrane bound ATPases in isoproterenol (ISO)-induced myocardial infarction in rats."7.75Effect of green tea and vitamin E combination in isoproterenol induced myocardial infarction in rats. ( Balaraman, R; Gandhi, C; Upaganlawar, A, 2009)
" This study was designed to evaluate the protective effect of gallic acid on cardiac marker enzymes, troponin-T, LDH-isoenzyme pattern, lipid peroxidation products and antioxidant status in isoproterenol (ISO)-induced myocardial infarction in male Wistar rats."7.75Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats. ( Prince, PS; Priscilla, DH, 2009)
"The study aimed to evaluate the protective role of myricetin obtained from Vitis vinifera (Vitaceae) on heart rate, electrocardiographic (ECG) patterns, vascular reactivity to catecholamines, cardiac marker enzymes, antioxidant enzymes together with morphological and histopathological changes in isoproterenol (ISO) induced myocardial infarction (MI) in male Wistar rats."7.75Cardioprotective potential of myricetin in isoproterenol-induced myocardial infarction in Wistar rats. ( Ballero, M; Kasture, S; Maxia, A; Mohan, M; Tiwari, R, 2009)
" calabura), a medicinal herb, on isoproterenol-induced myocardial infarction (MI) in rat models."7.75Effects of Muntingia calabura L. on isoproterenol-induced myocardial infarction. ( Brindha, P; Jayasri, J; Nivethetha, M, 2009)
" In the present study, we investigated the protective effect of betaine, a potent lipotropic molecule, on changes in the levels of membrane-bound ATPase activities, lipid peroxidation, sulfhydryl activities, and mineral status in isoprenaline-induced myocardial infarction in Wistar rats, an animal model of myocardial infarction in man."7.75Protective effect of betaine on changes in the levels of membrane-bound ATPase activity and mineral status in experimentally induced myocardial infarction in Wistar rats. ( Anandan, R; Buddhan, S; Ganesan, B; Jeyakumar, R, 2009)
"The present study was designed to evaluate the cardioprotective potential of salvianolic acid A on isoproterenol-induced myocardial infarction in rats."7.75Cardioprotective effect of salvianolic acid A on isoproterenol-induced myocardial infarction in rats. ( Du, GH; Tian, S; Wang, SB; Yang, F; Yang, HG; Yang, XY, 2009)
"The goal of this study was to investigate whether sub-chronic anti-oxidant treatment with ascorbic acid (Vit C) is able to protect the heart against myocardial infarction."7.75Ascorbic acid prevents acute myocardial infarction induced by isoproterenol in rats: role of inducible nitric oxide synthase production. ( Bergamaschi, CT; Buttros, JB; Campos, RR; Oshima, CT; Ribeiro, DA, 2009)
"An ultra-performance liquid chromatography/time-of-flight mass spectrometry (UPLC/TOF-MS)-based metabolomic approach was developed to characterize the metabolic profile associated with isoproterenol (ISO)-induced myocardial infarction (MI)."7.75Metabolomic profiling of rat serum associated with isoproterenol-induced myocardial infarction using ultra-performance liquid chromatography/time-of-flight mass spectrometry and multivariate analysis. ( Chen, X; Hu, P; Liang, QL; Liang, XP; Luo, GA; Wang, YM; Zhang, HY, 2009)
"We demonstrated that propranolol reduced the incidence of arrhythmias in a rat model of myocardial infarction by coronary artery occlusion."7.75MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection. ( Dong, D; Li, B; Li, X; Lu, Y; Pan, Z; Qiao, G; Shan, H; Song, W; Xu, C; Yang, B; Zhang, B; Zhang, F; Zhang, Y, 2009)
" The present study has been designed to investigate whether telmisartan treatment attenuates the development of acute myocardial infarction in isoproterenol-treated rats by restoring hemodynamic, biochemical, histopathological and ultrastructural changes."7.75Myocardial salvaging effect of telmisartan in experimental model of myocardial infarction. ( Arora, S; Arya, DS; Goyal, S; Joshi, S; Kumari, S; Mittal, R; Nag, TC; Ray, R, 2009)
"In the present study, cardioprotective effect of aqueous extract of fruits of Embelia ribes Burm (ER) was evaluated in a rat model having acute myocardial infarction, induced by isoproterenol (5."7.74Cardioprotective effect of aqueous extract of Embelia ribes Burm fruits against isoproterenol-induced myocardial infarction in albino rats. ( Ansari, MN; Bhandari, U; Islam, F, 2008)
" This study was aimed to evaluate the preventive role of naringin on cardiac troponin T (cTnT), lactate dehydrogenase (LDH)-isoenzyme, cardiac marker enzymes, electrocardiographic (ECG)-patterns and lysosomal enzymes in isoproterenol (ISO)-induced myocardial infarction (MI) in male Wistar rats."7.74Preventive effect of naringin on cardiac markers, electrocardiographic patterns and lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats. ( Rajadurai, M; Stanely Mainzen Prince, P, 2007)
"The protective effect of PUFA concentrate prepared from fish oil on isoproterenol-induced myocardial infarction in male albino rats was investigated with respect to changes in the levels of diagnostic marker enzymes, cholesterol, triglycerides, free fatty acids, phospholipids, reduced glutathione (GSH) and lipid peroxides (LPO)."7.74Protective effect of n-3 polyunsaturated fatty acids concentrate on isoproterenol-induced myocardial infarction in rats. ( Anandan, R; Mathew, S; Sankar, TV; Viswanathan Nair, PG, 2007)
"The present study was designed to evaluate the preventive role of rutin on lipids, lipoproteins, and ATPases in normal and isoproterenol (ISO)-induced myocardial infarction in rats."7.74Preventive effect of rutin on lipids, lipoproteins, and ATPases in normal and isoproterenol-induced myocardial infarction in rats. ( Karthick, M; Stanely Mainzen Prince, P, 2007)
"In our investigation,we used short-time model of myocardial infarction of rats induced by high dose of isoproterenol (ISP)."7.74Troponin T and histological characteristics of rat myocardial infarction induced by isoproterenol. ( Hasić, S; Jadrić, R; Kiseljaković, E; Mornjaković, Z; Winterhalter-Jadrić, M, 2007)
"Increased oxidative stress and antioxidant deficit have been suggested to play a major role in isoproterenol-induced myocardial infarction."7.74Cardioprotective effect of alpha-mangostin, a xanthone derivative from mangosteen on tissue defense system against isoproterenol-induced myocardial infarction in rats. ( Devi Sampath, P; Vijayaraghavan, K, 2007)
" The present study is undertaken to evaluate the preventive role of naringin on mitochondrial enzymes in isoproterenol (ISO)-induced myocardial infarction in male albino Wistar rats."7.74Preventive effect of naringin on cardiac mitochondrial enzymes during isoproterenol-induced myocardial infarction in rats: a transmission electron microscopic study. ( Prince, PS; Rajadurai, M, 2007)
"The present study was designed to investigate whether fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, would attenuate the acute myocardial infarction in isoproterenol-treated rat model via maintaining activities of endogenous antioxidant enzymes."7.74Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat. ( Dai, G; Xu, Q; Yan, L; Zheng, J; Zheng, P; Zhou, R, 2008)
" The aim of the present study was to evaluate the role of aldosterone and angiotensin II on formation of left ventricular fibrosis induced by chronic beta-adrenergic stimulation with isoproterenol (iso) in the rat heart failure model induced by myocardial infarction (MI)."7.73Inhibition of catecholamine-induced cardiac fibrosis by an aldosterone antagonist. ( Bos, R; Findji, L; Lechat, P; Médiani, O; Mougenot, N; Vanhoutte, PM, 2005)
"We demonstrate the effect of Aegle marmelos leaf extract (AMLEt) and alpha-tocopherol on plasma lipids, lipid peroxides and marker enzymes in rats with isoproterenol (ISO)-induced myocardial infarction."7.73Comparative effects of Aegle marmelos extract and alpha-tocopherol on serum lipids, lipid peroxides and cardiac enzyme levels in rats with isoproterenol-induced myocardial infarction. ( Prince, PS; Rajadurai, M, 2005)
"We have examined the protective effect of taurine on the myocardial antioxidant defense system in isoprenaline (isoproterenol)-induced myocardial infarction in rats, an animal model of myocardial infarction in man."7.73Protective effect of taurine on myocardial antioxidant status in isoprenaline-induced myocardial infarction in rats. ( Anandan, R; Devadasan, K; Farvin, KH; Kumar, SH; Shiny, KS, 2005)
"Isoproterenol (ISPH) induced myocardial infarction was confirmed by disturbances in serum and heart tissue marker enzymes such as lactate dehydrogenase (LDH), creatine phospho kinase (CPK), aspartate transaminase (AST) and alanine transaminase (ALT), increased level of lipid peroxidation and histopathological changes in the heart of ISPH administered rats."7.73Cardioprotective effect of mangiferin on isoproterenol induced myocardial infarction in rats. ( Devi, CS; Jainu, M; Prabhu, S; Sabitha, KE, 2006)
"In the present study, chronic treatment of atorvastatin was evaluated on isoproterenol-induced myocardial infarction."7.73Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats. ( Balaraman, R; Bothara, SB; Majithiya, JB; Trivedi, CJ, 2006)
" (Anacardiaceae), on isoproterenol (ISPH)-induced myocardial infarction (MI) in rats through its antioxidative mechanism."7.73Role of mangiferin on biochemical alterations and antioxidant status in isoproterenol-induced myocardial infarction in rats. ( Devi, CS; Jainu, M; Prabhu, S; Sabitha, KE, 2006)
"The effect of fish oil treatment on the activities of antioxidants such as superoxide dismutase, catalase, glutathione peroxidase, glutathione-s-transferase, and glutathione, as well as the level of the lipid peroxidation marker thiobarbituric reactive substance was studied in isoproterenol-induced myocardial infarction (MI)."7.73Modulatory effect of fish oil on the myocardial antioxidant defense system in isoproterenol-induced myocardial infarction. ( Devi, CS; Padma, VV; Ramkumar, KM, 2006)
" This study aimed to evaluate the preventive role of rutin on lipid peroxides and antioxidants in normal and isoproterenol-induced myocardial infarction in rats."7.73Preventive effect of rutin, a bioflavonoid, on lipid peroxides and antioxidants in isoproterenol-induced myocardial infarction in rats. ( Karthick, M; Stanely Mainzen Prince, P, 2006)
"Our study evaluates the preventive effect of S-allyl cysteine sulfoxide (SACS) on lipid peroxidative products and enzymic and nonenzymic antioxidants in isoproterenol (ISO) induced myocardial infarction in rats."7.73Antilipoperoxidative and antioxidant effects of S-allyl cysteine sulfoxide on isoproterenol-induced myocardial infarction in Wistar rats. ( Quine, SD; Sangeetha, T, 2006)
"This study was designed to evaluate the preventive effect of naringin in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."7.73Preventive effect of naringin on lipids, lipoproteins and lipid metabolic enzymes in isoproterenol-induced myocardial infarction in Wistar rats. ( Rajadurai, M; Stanely Mainzen Prince, P, 2006)
"We studied the cardioprotective effect of squalene on isoprenaline-induced myocardial infarction in male albino rats with respect to changes in the levels of lipid components in plasma and heart tissue."7.73Cardioprotective effect of squalene on lipid profile in isoprenaline-induced myocardial infarction in rats. ( Anandan, R; Farvin, KH; Kumar, SH; Mathew, S; Nair, PG; Sankar, TV; Shiny, KS, 2006)
" Cardiac lesions induced by isoproterenol (ISO) are characterized by myocardial necrosis and exudative infiltration."7.72Effect of D-003 on isoproterenol-induced myocardial necrosis in rats. ( Arruzazabala, ML; Carbajal, D; González, J; Más, R; Mendoza, S; Molina, V; Noa, M, 2003)
"The protective effect of L-arginine and L-lysine on lysosomal enzymes and membrane bound ATPases was examined on isoproterenol induced myocardial infarction in rats."7.72Effect of L-arginine and L-lysine on lysosomal hydrolases and membrane bound phosphatases in experimentally induced myocardial infarction in rats. ( Devaki, T; Ebenezar, KK; Sathish, V, 2003)
"The synergistic protective effect of nicorandil (KATP channel opener) and amlodipine (calcium channel blocker) on mitochondrial respiration and mitochondrial lipid contents were examined on isoproterenol-induced myocardial infarction in rats."7.72Biochemical changes on the cardioprotective effect of nicorandil and amlodipine during experimental myocardial infarction in rats. ( Devaki, T; Ebenezar, KK; Sathish, V, 2003)
"Animals with heart failure exhibited depressions in ventricular function, positive inotropic response to isoproterenol, beta-AR receptor density and basal AC activity; these changes were also attenuated by PLC treatment."7.72Improvement of cardiac function and beta-adrenergic signal transduction by propionyl L-carnitine in congestive heart failure due to myocardial infarction. ( Dhalla, NS; Ferrari, R; Sethi, R; Wang, X, 2004)
"This study was designed to examine the effects of squalene on tissue antioxidant status in isoproterenol-induced myocardial infarction in male albino rats."7.72Effect of squalene on tissue defense system in isoproterenol-induced myocardial infarction in rats. ( Anandan, R; Kumar, SH; Sabeena Farvin, KH; Sankar, TV; Shiny, KS; Thankappan, TK, 2004)
"Myocardial infarction was produced by subcutaneous administration of isoproterenol hydrochloride (85 mg/kg b."7.72Comparative account of certain enzymes in the serum of homo-iothermal vertebrates subjected to production of myocardial infarction by isoproterenol hydrochloride. ( Gaur, M; Kumar, S, 2003)
" The aim of the present study is to study the effect of folic acid and Vitamin B(12) supplementation on isoprenaline (ISO)-induced myocardial infarction (MI) in hyperhomocysteinemic rats."7.71Folic acid and vitamin B(12) supplementation attenuates isoprenaline-induced myocardial infarction in experimental hyperhomocysteinemic rats. ( Hagar, HH, 2002)
"Myocardial infarction (MI) was produced in rats with 85, 200 and 300 mg/kg of isoproterenol (ISO) administered subcutaneously (sc) twice at an interval of 24 h."7.71Cardioprotective potential of ocimum sanctum in isoproterenol induced myocardial infarction in rats. ( Arya, DS; Gupta, SK; Joshi, S; Kishore, K; Sharma, M, 2001)
"The synergistic effects of nicorandil (KATP-channel opener) and amlodipine (calcium-channel blocker) on heart mitochondrial enzymes and the mitochondrial antioxidant defence system was examined on isoproterenol-induced myocardial infarction in rats."7.71Synergistic effect of nicorandil and amlodipine on mitochondrial function during isoproterenol-induced myocardial infarction in rats. ( Devaki, T; Ebenezar, KK; Sathish, V; Vimal, V, 2002)
" Male Wistar rats with ligation-induced myocardial infarction were assigned to placebo or treatment with mibefradil (10 mg/kg/day), verapamil (8 mg/kg/day), or amlodipine (4 mg/kg/day) by oral gavage starting 7 days before the induction of myocardial infarction."7.70Differential effects of mibefradil, verapamil, and amlodipine on myocardial function and intracellular Ca(2+) handling in rats with chronic myocardial infarction. ( Meissner, A; Min, JY; Sandmann, S; Simon, R; Unger, T, 1999)
" To examine the status of beta-adrenergic receptors and postadrenergic receptor mechanisms in congestive heart failure due to myocardial infarction, the left coronary artery in rats was ligated for 4 and 8 weeks before studying the hemodynamic and biochemical changes due to isoproterenol, a beta-adrenoceptor agonist, or forskolin, a postreceptor agonist."7.69Inotropic responses to isoproterenol in congestive heart failure subsequent to myocardial infarction in rats. ( Dhalla, NS; Sethi, R, 1995)
"The mechanism of exercise-induced ST-segment elevation in previous myocardial infarction was investigated using isoproterenol infusion with atrial pacing to simulate exercise hemodynamics in seven closed chest dogs with myocardial infarction."7.69[Isoproterenol induces ST-segment elevation without wall motion aggravation and myocardial ischemia in experimental myocardial infarction]. ( Katori, R; Yamamoto, T, 1995)
"The effect of alpha-tocopherol (6 mg/100 g body wt, orally, daily for 90 days) pretreatment in isoproterenol (20 mg/100 g body wt, subcutaneously, twice at an interval of two days at the end of the alpha-tocopherol pretreatment) induced myocardial infarction was studied in rats."7.69Effect of alpha-tocopherol on isoproterenol induced myocardial infarction in rats--electrocardiographic biochemical and histological evidences. ( Ithayarasi, AP; Padmavathy, VN; Shyamala Devi, C, 1996)
"The effect of alpha-tocopherol pretreatment on lipid peroxidation and antioxidant status in isoproterenol induced myocardial infarction was studied in rats."7.69Effect of alpha-tocopherol on lipid peroxidation in isoproterenol induced myocardial infarction in rats. ( Devi, CS; Ithayarasi, AP, 1997)
"Myocardial infarction was induced in albino rats by the subcutaneous administration of isoproterenol."7.68Collagen levels in isoproterenol induced myocardial infarction in rats. ( Puvanakrishnan, R; Ravichandran, LV, 1993)
"2 mg/100 g body wt orally for 30 days) on myocardial infarction induced by isoproterenol (200 mg/kg body wt, subcutaneously for 2 days) has been studied in rats using activities of creatine kinase, aspartate amino transaminase, alanine amino transaminase and lactate dehydrogenase and levels of lipid peroxides as standard markers."7.68Effect of aspirin on isoproterenol induced myocardial infarction--a pilot study. ( Devi, CS; Geetha, A; Manjula, TS, 1992)
"Effects of acute myocardial infarction (48 h) on cardiovascular responses to (+/-)-, (-)-, and (+)-dobutamine were studied in isolated perfused rat hearts."7.68Cardiovascular responses to the stereoisomers of dobutamine in isolated rat hearts 48 hours after acute myocardial infarction. ( Porsius, AJ; van Rooij, HH; Vleeming, W; Wemer, J, 1991)
"The aim was to compare the effects of two novel angiotensin converting enzyme (ACE) inhibitors, spirapril and zofenopril, on cardiac remodelling in rats with congestive heart failure after myocardial infarction."7.68Converting enzyme inhibition after experimental myocardial infarction in rats: comparative study between spirapril and zofenopril. ( de Graeff, PA; de Langen, CD; Pinto, YM; van Gilst, WH; van Wijngaarden, J; Wesseling, H, 1991)
"Effect of ethanol administration on the severity of myocardial infarction induced by isoproterenol in rats was studied."7.68Effect of ethanol administration on metabolism of lipids in heart and aorta in isoproterenol induced myocardial infarction in rats. ( Kumari, S; Kurup, PA; Menon, PV; Remla, A, 1991)
"Effect of feeding safflower oil and coconut oil in experimental myocardial infarction induced by isoproterenol in rats was studied."7.68Effect of coconut oil & safflower oil on lipids in isoproterenol induced myocardial infarction in rats. ( Kurup, PA; Menon, PV; Remla, A, 1991)
", beta-glucuronidase, beta-N-acetylglucosaminidase, beta-galactosidase, beta-glucosidase, alpha-glucosidase, alpha-galactosidase, alpha-mannosidase, cathepsin B, cathepsin D, and collagenolytic cathepsin, in serum and heart of rats subject to myocardial infarction with isoproterenol, were studied during the periods of peak infarction and recovery."7.68Influence of isoproterenol-induced myocardial infarction on certain glycohydrolases and cathepsins in rats. ( Joseph, KT; Puvanakrishnan, R; Ravichandran, LV, 1991)
"The alterations in the heart lysosomal stability following isoproterenol induced myocardial infarction were studied in albino rats."7.68Alterations in the heart lysosomal stability in isoproterenol induced myocardial infarction in rats. ( Joseph, KT; Puvanakrishnan, R; Ravichandran, LV, 1990)
"The influence of isoproterenol on induction of ventricular arrhythmias was evaluated in 10 normal dogs and 17 dogs with experimentally induced myocardial infarction."7.68Effect of isoproterenol on induction of ventricular tachyarrhythmias in the normal and infarcted canine heart. ( Hunt, GB; Ross, DL, 1990)
"Beta-Adrenoceptor agonists, such as isoproterenol, produce ventricular fibrillation and myocardial necrosis in rats."7.67Ventricular fibrillation threshold and myocardial cyclic AMP production in rats sensitive or resistant to isoproterenol. ( Balazs, T; Jordan, AW; Joseph, X, 1984)
"The effect of vitamin E administration on the severity of myocardial infarction induced by isoproterenol on rats was studied."7.67Effect of vitamin E on the severity of myocardial infarction induced by isoproterenol. ( Kumari, SS; Menon, VP; Muraleedharan, D; Varghese, A, 1989)
"The effects of the intravenous administration of hyaluronidase (HY; 2,500 IU/kg) and urokinase (UK; 20,000 and 40,000 IU/kg), alone or in combination, on the isoproterenol (ISP) induced myocardial infarction (MI) in rats, were studied."7.67The co-operative action of hyaluronidase and urokinase on the isoproterenol-induced myocardial infarction in rats. ( Antonetti, F; Borrelli, F; Caprino, L; Martelli, F, 1986)
"The effect of administration of carnitine on the severity of myocardial infarction in rats induced by isoproterenol was studied by following histopathological and biochemical parameters."7.67Effect of administration of carnitine on the severity of myocardial infarction induced by isoproterenol in rats. ( Kurup, PA; Mathew, S; Menon, PV, 1986)
" Seven days later, the animals were challenged with a dose of isoproterenol which would produce massive myocardial infarction and 50-60% mortality in non-treated animals."7.67Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats. ( Wexler, BC, 1985)
"Prophylactic effects of sulfinpyrazone (100 mg/Kg), aspirin (5 mg/Kg, 50 mg/Kg), and propranolol (2 mg/Kg, 10 mg/Kg) on myocardial necrosis and hypertrophy induced by isoproterenol were examined."7.66Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis. ( Hashimoto, H; Ogawa, K, 1981)
"The effect of exercise on the severity of isoproterenol-induced acute myocardial infarction was studied in male rats."7.66Beneficial effects of exercise on l-isoproterenol induced myocardial infarction in male rats. ( Darrah, MI; Engen, RL, 1982)
"To determine the relative effect of body weight and physical inactivity on susceptibility to drug-induced myocardial infarction, randomly selected groups of 100-day-old male Sprague-Dawley rats were subjected to a 10-wk program of exercise training and (or) to caloric restriction followed by two subcutaneous injections of L-isoproterenol."7.66Relative role of caloric restriction and exercise training upon susceptibility to isoproterenol-induced myocardial infarction in male rats. ( Beitz, DC; Crandall, DL; Feirer, RP; Griffith, DR, 1981)
" Some of the animals were treated with the anti-hyperuricemic agent, allopurinol, either before or during the induction of myocardial infarction."7.66Allopurinol amelioration of the pathophysiology of acute myocardial infarction in rats. ( McMurtry, JP; Wexler, BC, 1981)
"Tachycardia- and bradycardia-dependent, left anterior and left posterior hemiblocks as transient phenomena were registered in two patients spontaneously, and especially as a consequence of isoproterenol infusion."7.66Transient tachycardia- and bradycardia-dependent left anterior and left posterior hemiblocks. Effects of isoproterenol. ( Alvarez, JA; Kretz, A; Leguizamon Palumbo, JR; Martinez Martinez, JA; Suarez, LD, 1981)
"The effect of isoproterenol infusion on regional myocardial perfusion and tissue oxygenation during acute myocardial infarction was investigated in anesthetized dogs."7.66Effect of isoproterenol on regional myocardial perfusion and tissue oxygenation in acute myocardial infarction. ( Grover, FL; Horwitz, LD; Schwartz, DA, 1979)
"Adult male and female Sprague-Dawley rats were subjected to an isoproterenol-induced myocardial infarction."7.66Effect of gonadectomy on isoproterenol-induced myocardial infarction. ( Greenberg, BP; Wexler, BC, 1979)
" suggest that the myocardial infarction induced by isoproterenol in the rat may be determined by phenomenons of intracoronaric platelets aggregation."7.66[The role of the platelets in myocardial infarction induced by isoproterenol in the rat (author's transl)]. ( Cacciapuoti, AA; Genovese, A; Giuffrida, G; Mazza, F; Polverino, W, 1979)
"Changes in myocardial zinc level was followed up over a period of 5 days after producing myocardial necrosis in albino rats by subcutaneous injection of isoproterenol, 85 mg/kg body weight."7.66A temporal profile of myocardial zinc changes after isoproterenol induced cardiac necrosis. ( Ahmad, MS; Hasan, MZ; Jamil, SA; Kumar, S; Mathew, BM; Seth, TD, 1978)
"Male and female, arteriosclerotic and non-arteriosclerotic rats were treated with the anti-lipemic agent, clofibrate, for 8 days and then subjected to an acute myocardial infarction by injecting them with two large doses of isoproterenol spaced 24 hours apart."7.66Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats. ( Greenberg, BP; Wexler, BC, 1978)
"The effect of exercise on the severity of isoproterenol-induced myocardial infarction was studied in male rats."7.65Effects of exercise on the severity of isoproterenol-induced myocardial infarction. ( Bonner, HW; Jessup, GT; Landiss, CW; Riggs, CE, 1977)
"Trapidil increases the isoprenalin-induced necrosis of the myocardium in the rat."7.65[Modification of the isoprenaline-induced myocardial necrosis using trapidil]. ( Lampe, D; Lange, B; Mai, I, 1976)
"A 39-year-old women inhaled approximately 675 mg of aerosolized isoproterenol in less than three days during an asthmatic attack."7.65An electrocardiographic pattern of acute myocardial infarction associated with excessive use of aerosolized isoproterenol. ( Aelony, Y; Beall, G; Laks, MM, 1975)
"Male and female, arteriosclerotic and nonarteriosclerotic rats were subjected to acute myocardial infarction by two, subcutaneous injections (spaced 24 hr apart) of isoproterenol."7.65Metabolic and histopathologic changes in arteriosclerotic versus nonarteriosclerotic rats following isoproterenol-induced myocardial infarction with superimposed diabetes. ( Wexler, BC, 1975)
"Circulating prolactin levels were monitored in nonarteriosclerotic, arteriosclerotic, and hormonally sterilized male and female Sprague-Dawley rats during the acute necrosis and repair phases of myocardial infarction induced by isoproterenol."7.65Serum prolactin levels in rats following isoproterenol-induced myocardial infarction. ( Lewis, BK; Wexler, BC, 1975)
"Isoproterenol (ISO), a drug which causes an increased strength of myocardial contraction when administered to animals in mug/kg doses, causes myocardial necrosis when given mg/kg doses."7.65Calcium as mediator of isoproterenol-induced myocardial necrosis. ( Bloom, S; Davis, DL, 1972)
"Modern medicine has been used to treat myocardial infarction, a subset of cardiovascular diseases, and have been relatively effective but not without adverse effects."6.55Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review. ( Ramamurthy, S; Thanikachalam, PV; Wong, ZW, 2017)
"Scopoletin pre-treatment with ISO (25 and 50 mg/kg b."5.91Cardioprotective Role of Scopoletin on Isoproterenol-Induced Myocardial Infarction in Rats. ( Ibrahim, IAA; Rong, N; Yang, R; Zhang, W, 2023)
"Protocatechuic acid (PCA) is a polyphenolic compound with various potent biological activities."5.91Protocatechuic acid reverses myocardial infarction mediated by β-adrenergic agonist via regulation of Nrf2/HO-1 pathway, inflammatory, apoptotic, and fibrotic events. ( Elhefny, MA; Jiang, H; Kassab, RB; Li, L; Lokman, MS; Ma, H; Sberi, HA; Xia, B; Zhang, Y, 2023)
"The cardiac mitochondrial damage and cardiac hypertrophy pathways are intimately associated with the pathology of myocardial infarction (MI)."5.91Protective effects of β-caryophyllene on mitochondrial damage and cardiac hypertrophy pathways in isoproterenol-induced myocardial infarcted rats. ( Ponnian, SMP; Stanely, SP; Yovas, A, 2023)
"Isoproterenol (ISO) was used to induce MI injury in mice and H9c2 cells."5.91Curdione inhibits ferroptosis in isoprenaline-induced myocardial infarction via regulating Keap1/Trx1/GPX4 signaling pathway. ( Cheng, Y; Liang, Q; Liu, Z; Shi, S; Wang, H; Xie, B; Zhang, R, 2023)
"Pre-treatment of fraxetin in group IV experimental rats resulted in decreased cardiac weight, diminished level of cardiac markers (cardiac troponin T (cTnT), creatine kinase, creatine kinase-MB, and cardiac troponin I (cTnI)), reduced level of oxidative stress biomarkers (LOOH and TBARS) in the plasma and cardiac tissue, amplified level of enzymes in antioxidant defense system (catalase (CAT), superoxide dismutase (SOD), glutathione (GSH), and glutathione peroxidase (GPx)) in the plasma and heart tissue, and elevated level of ATPase activities."5.72Effect of Fraxetin on Oxidative Damage Caused by Isoproterenol-Induced Myocardial Infarction in Rats. ( Chen, G; Wang, L; Yin, Y; You, H, 2022)
"Visnagin (VIS) is a natural bioactive component of Ammi visnaga, with promising radical scavenging and anti-inflammatory activities."5.62Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats. ( Abukhalil, MH; Al-Amarat, W; Al-Swailmi, FK; Aladaileh, SH; Alanazi, KM; Alfwuaires, MA; Algefare, AI; Althunibat, OY; Hussein, OE; Kamel, EM; Mahmoud, AM; Saghir, SA, 2021)
"Ferruginol (FGL) is a major polyphenols and terpenoids with numerous pharmacological activities including antioxidant and anti-inflammatory."5.62Ameliorative effect of ferruginol on isoprenaline hydrochloride-induced myocardial infarction in rats. ( Ali Alharbi, S; Chen, Y; Deng, Y; Feng, J; Li, H; Li, X; Wang, C; Wang, L; Zhang, X, 2021)
"Piperine pretreatment significantly prevented these changes in ISO treated group."5.56The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity. ( Aliev, G; Beeraka, NM; Chubarev, VN; Dhivya, V; Gavryushova, LV; Huang, CY; Mikhaleva, LM; Minyaeva, NN; Tarasov, VV; Viswanadha, VP, 2020)
"Pretreatment with nimodipine (10 and 15 mg/kg, i."5.51Effects of nimodipine, vinpocetine and their combination on isoproterenol-induced myocardial infarction in rats. ( Ansari, MA; Ekbbal, R; Haque, SE; Iqubal, A, 2019)
" At the end of dosing left ventricular functions was assessed to estimate its effect on cardiac functions."5.46Cardiaprotective effect of crocetin by attenuating apoptosis in isoproterenol induced myocardial infarction rat model. ( Ge, Z; Li, Y; Zhang, W, 2017)
"Piperine pre-treatment decreased the levels of serum markers, lipid peroxidation and PCC with increased antioxidant status in the heart tissues of ISO administered rats."5.46Piperine modulates isoproterenol induced myocardial ischemia through antioxidant and anti-dyslipidemic effect in male Wistar rats. ( Chirayil, HT; Dhivya, V; Huang, CY; Padma, VV; Priya, LB; Sathiskumar, S, 2017)
"Isorhapontigenin is a derivative of stilbene with chemical structure similar to resveratrol."5.43Cardioprotective effect of resveratrol analogue isorhapontigenin versus omega-3 fatty acids in isoproterenol-induced myocardial infarction in rats. ( Abbas, AM, 2016)
"Pre-treatment with ibuprofen (30, 60 and 90mg/kg p."5.43Inhibition of RhoA/Rho kinase by ibuprofen exerts cardioprotective effect on isoproterenol induced myocardial infarction in rats. ( Gandhi, T; Parikh, M; Patel, P; Shah, H, 2016)
"Zingerone pretreatment significantly (P<0."5.43Anti-inflammatory and anti-thrombotic effects of zingerone in a rat model of myocardial infarction. ( Hemalatha, KL; Stanely Mainzen Prince, P, 2016)
"Treatment with tamoxifen significantly controlled dyslipidemia, hypertension, bradycardia, oxidative stress, and reduced serum cardiac markers."5.40Beneficial role of tamoxifen in isoproterenol-induced myocardial infarction. ( Patel, BM; Rayabarapu, N, 2014)
"Isoproterenol (100 mg/kg) was injected subcutaneously for two consecutive days to induce myocardial infarction, and simultaneously tacrolimus was administered orally twice a day for three days."5.40Tacrolimus ameliorates functional disturbances and oxidative stress in isoproterenol-induced myocardial infarction. ( Garjani, A; Garjani, M; Hammami, M; Khorrami, A; Maleki-Dizaji, N, 2014)
"Metoprolol can inhibit the expression of c-fos and has a positive therapeutic effect on rats after AMI; the involvement effect of metoprolol on myocardial infarction might be correlated with its effect on the inhibition of c-fos."5.39The effect of c-fos on acute myocardial infarction and the significance of metoprolol intervention in a rat model. ( Ge, J; Goldstein, S; He, B; Li, Y; Ruiz, G; Zhang, M; Zhang, S, 2013)
"Pre-treatment with morin favorably restored the biochemical and functional parameters to near normal indicating morin to be a significant protective effect on cardiac mitochondrial function against ISO-induced MI in rats."5.38Protective effect of morin on cardiac mitochondrial function during isoproterenol-induced myocardial infarction in male Wistar rats. ( Al Numair, KS; Alsaif, MA; Baskar, AA; Chandramohan, G, 2012)
"Pretreatment with morin regulated the abnormalities in electrocardiograph and biomarkers."5.38Morin protects heart from beta-adrenergic-stimulated myocardial infarction: an electrocardiographic, biochemical, and histological study in rats. ( Arella, M; Boini, L; Maharajan, MK; Oddepalli, DR; Pogula, BK; Sabarimuthu, DQ, 2012)
"Acute myocardial infarction was induced by injecting the rats with two doses of isoproterenol (85 mg/kg/24 h, s."5.38Rosuvastatin promotes angiogenesis and reverses isoproterenol-induced acute myocardial infarction in rats: role of iNOS and VEGF. ( Abo-Gresha, NM; Zaitone, SA, 2012)
"Myocardial infarction was produced in rats with 65, 85, 120 and 200mg/kg of ISO administered subcutaneously (sc) twice at an interval of 24h."5.35Cardioprotective activity of Ginkgo biloba Phytosomes in isoproterenol-induced myocardial necrosis in rats: a biochemical and histoarchitectural evaluation. ( Naik, SR; Panda, VS, 2008)
"Myocardial infarction is the number one killer disease in many parts of the world."5.35Cardioprotective effect of 'Marutham' a polyherbal formulation on isoproterenol induced myocardial infarction in Wistar rats. ( Devika, PT; Prince, PS; Suman, S; Vaithianathan, M, 2008)
"Pretreatment with mangiferin (100 mg/kg body weight, intraperitoneally) for 28 days, significantly prevented the alterations and restored the enzyme activities to near-normal status."5.35Mechanism of protective action of mangiferin on suppression of inflammatory response and lysosomal instability in rat model of myocardial infarction. ( Devi, CS; Narayan, S; Prabhu, S, 2009)
"Myocardial infarction was experimentally induced with ISO (85 mg/kg) twice at 24 h interval."5.35Antilipoperoxidative and membrane stabilizing effect of diosgenin, in experimentally induced myocardial infarction. ( Jayachandran, KS; Rajamanickam, GV; Vasanthi, HR, 2009)
"Pretreatment with betaine daily for a period of 30 days to isoprenaline-induced rats prevented the changes in the activities of these lysosomal enzymes."5.35Protective effect of betaine on changes in the levels of lysosomal enzyme activities in heart tissue in isoprenaline-induced myocardial infarction in Wistar rats. ( Anandan, R; Ganesan, B, 2009)
"Isoproterenol treatment (80 mg/kg given over 2 days in two equal doses) caused arrhythmias and 60% mortality within 24 h of the last injection in the control group (C + ISO) group when compared with the saline control group (saline)."5.35Exercise training provides cardioprotection via a reduction in reactive oxygen species in rats submitted to myocardial infarction induced by isoproterenol. ( Barbosa, VA; Boeck, CR; Da Luz, G; Da Silva, S; De Pinho, RA; De Souza, CT; Frederico, MJ; Justo, SL; Medeiros, C; Silva, LA, 2009)
"Myocardial infarction was induced in rats by subcutaneous injection of isoproterenol (ISO) (150 mg kg(-1)) at an interval of 24 h for 2 days."5.35Protective effect of S-allyl cysteine sulphoxide (alliin) on glycoproteins and hematology in isoproterenol induced myocardial infarction in male Wistar rats. ( Quine, SD; Sangeetha, T, 2008)
"Carvedilol is a combined alpha(1)- and beta-adrenoceptor antagonist."5.33Carvedilol blockade of alpha1- and beta-adrenoceptor induced inotropic responses in rats with congestive heart failure. ( Bøkenes, J; Osnes, JB; Qvigstad, E; Schiander, I; Sejersted, OM; Sjaastad, I; Skomedal, T; Solberg, L, 2005)
" AEC was administered orally to male albino rats (150-200 g), at a dosage of 0."5.33Pretreatment with alcoholic extract of Crataegus oxycantha (AEC) activates mitochondrial protection during isoproterenol - induced myocardial infarction in rats. ( Devaraj, SN; Jayalakshmi, R; Thirupurasundari, CJ, 2006)
"Pretreatment with propranolol or labetalol counteracted the appearance of the myocardial histological alterations and the associated ECG and biochemical lesions."5.32Isoproterenol-induced myocardial infarction in rabbits. Protection by propranolol or labetalol: a proposed non-invasive procedure. ( Accinni, R; Bonacina, E; Brenna, S; Pinelli, A; Tomasoni, L; Trivulzio, S, 2004)
"Myocardial infarction is usually induced in small animals by means of invasive procedures: the aim of this study was to cause heart necrosis lesions by non-invasive means."5.32Myocardial infarction non-invasively induced in rabbits by administering isoproterenol and vasopressin: protective effects exerted by verapamil. ( Bertolini, B; Bonacina, E; Brenna, S; Pinelli, A; Tomasoni, L; Trivulzio, S; Vignati, S, 2004)
"Acute myocardial infarction is the second cause of mortality in most countries, therefore, it is important to know the evolution and sequence of the physiological and biochemical changes involved in this pathology."5.30Sequential changes of energy metabolism and mitochondrial function in myocardial infarction induced by isoproterenol in rats: a long-term and integrative study. ( Aranda-Fraustro, A; Chagoya de Sánchez, V; Cota-Garza, MD; Cruz, D; Hernández-Muñoz, R; López-Barrera, F; Suárez, J; Vidrio, S; Yañez, L, 1997)
"The propranolol treated animals had higher LV end-diastolic pressures (27+/-2* vs 20+/(-3 mmHg) and a more restricted LV diastolic filling pattern (increased ratio of early to late filling velocities and more rapid E wave deceleration rate)."5.30Effects of propranolol treatment on left ventricular function and intracellular calcium regulation in rats with postinfarction heart failure. ( Douglas, PS; Katz, SE; Litwin, SE; Morgan, JP, 1999)
"Mibefradil treatment increased MAP and dP/dtmax and decreased LVEDP and HR in infarcted rats."5.30Effects of the calcium channel antagonist mibefradil on haemodynamic parameters and myocardial Ca(2+)-handling in infarct-induced heart failure in rats. ( Meissner, A; Min, JY; Sandmann, S; Unger, T, 1999)
"Nisoldipine was more effective in preventing cardiac necrosis as compared to nitrendipine and nimodipine."5.29Effect of nitrendipine, nimodipine and nisoldipine on experimentally induced myocardial infarction in rats. ( Kaur, AH; Mathur, SK; Singh, J; Srivastava, RK, 1995)
"Aspirin treatment is found to counteract the effect of isoproterenol on lipid and lipid peroxide formation and associated enzyme changes in heart mitochondria."5.29Effect of aspirin on mitochondrial lipids in experimental myocardial infarction in rats. ( Devi, CS; Manjula, TS, 1993)
"Rats treated with isoproterenol (30 mg/100 g body weight) showed a significant increase in serum lysosomal hydrolase activities, which were found to decrease after curcumin treatment."5.29Effect of curcumin on certain lysosomal hydrolases in isoproterenol-induced myocardial infarction in rats. ( Nirmala, C; Puvanakrishnan, R, 1996)
"Curcumin pre- and co-treatment decreased the severity of pathological changes and thus, could have a protective effect against the damage caused by myocardial infarction (MI)."5.29Protective role of curcumin against isoproterenol induced myocardial infarction in rats. ( Nirmala, C; Puvanakrishnan, R, 1996)
"Aspirin treated rats showed lower mortality rate and smaller changes in the myocardium on histopathological examination when compared to corresponding animals given isoproterenol alone."5.28Protective action of aspirin in experimental myocardial infarction induced by isoproterenol in rats and its effect on lipid peroxidation. ( Menon, VP; Muraleedharan, D; Sushama Kumari, S; Varghese, A, 1990)
"Pretreatment with sulfinpyrazone reduced isoproterenol-induced lesions by 42%."5.26Reduction in the severity of myocardial infarction by sulfinpyrazone. ( Innes, IR; Weisman, H, 1981)
"The necrosis was confirmed by ECG changes, increased serum activities of AspAT, AlAT, GPT and LDH, and by histological examination."5.26A temporal profile of changes in myocardial manganese after isoprenaline induced cardiac necrosis in albino rats. ( Ahmad, M; Hasan, MZ; Jameel, SA; Kumar, S; Mathew, BM; Seth, TD, 1979)
"The greater sensitivity of phase 1a arrhythmias to beta-blockade and the lack of a decrease in ventricular fibrillation threshold during phase 1b might indicate differences in the genesis of arrhythmias and fibrillation in phases 1a and 1b."5.26Prophylaxis of ventricular fibrillation after acute experimental coronary occlusion by chronic beta-adrenoceptor blockade with atenolol. ( Bucher, P; Meesmann, W; Menken, U; Wiegand, V, 1979)
" Isoproterenol (ISP)-induced myocardial ischemia is a classical model to screen the cardioprotective effects of various pharmacological interventions."4.98Isoproterenol-induced cardiac ischemia and fibrosis: Plant-based approaches for intervention. ( Allawadhi, P; Godugu, C; Khurana, A; Kumari, P; Sayed, N, 2018)
"Myocardial infarction was induced by injecting subcutaneous isoproterenol (5 mg/kg once for 7 consecutive days) to establish an experimental heart failure model."4.31Comparative Efficacy of Levosimendan, Ramipril, and Sacubitril/ Valsartan in Isoproterenol-induced Experimental Heart Failure: A Hemodynamic and Molecular Approach. ( Afzal, O; Akhtar, MS; Altamimi, A; Hassan, MZ; Hassan, Q; Mohammad, AAS; Sharma, AK; Tabassum, F, 2023)
"This study aimed to investigate the cardioprotective effect of SJP against isoproterenol-induced acute myocardial infarction (AMI) by integrating the gut microbiome and metabolome."4.31Microbiome-metabolome reveals that the Suxiao Jiuxin pill attenuates acute myocardial infarction associated with fatty acid metabolism. ( Liao, J; Ma, C; Wu, G; Zhang, W; Zhang, Y, 2023)
" However, researchers recently investigated the potential cardioprotective effects of taraxerol utilizing an isoproterenol (ISO)-induced cardiotoxicity model among Sprague Dawley rats."4.31Effects of Taraxerol on Oxidative and Inflammatory Mediators in Isoproterenol-Induced Cardiotoxicity in an Animal Model. ( Alam, A; Alkholifi, FK; Aodah, AH; Devi, S; Foudah, AI; Yusufoglu, HS, 2023)
" The objective of this study was to analyze the effect of essential oil of Alpinia zerumbet (EOAz) on cardiovascular and autonomic function in rats with isoproterenol-induced myocardial infarction."4.31Effect of essential oil of Alpinia zerumbet on cardiovascular and autonomic function in rats with isoproterenol induced acute myocardial infarction. ( Costa, PPC; Fechine, FV; Holanda, TM; Ingram, C; Maia, PHF; Moraes Filho, MO; Moraes, MEA; Rocha, DG; Silveira, JAM, 2023)
" This study was conducted to assess the cardioprotective action of TPN against isoproterenol (ISO)-induced cardiotoxicity."4.12Alpha-terpineol prevents myocardial damage against isoproterenol-MI induced in Wistar-Kyoto rats: new possible to promote cardiovascular integrity. ( Bernardino, AC; de Oliveira, KRV; Machado, MLDP; Oliveira, AP; Paulino, ET; Quintans-Júnior, LJ; Ribeiro, ÊAN; Rodrigues, AKBF, 2022)
" The present study aimed to investigate the effect of TQ on apoptotic parameters and MMP-9 expression in isoproterenol (ISP)-induced myocardial infarction (MI)."4.12Thymoquinone attenuates isoproterenol-induced myocardial infarction by inhibiting cytochrome C and matrix metalloproteinase-9 expression. ( Awad, A; Badr, AM; El-Bakly, WM; El-Demerdash, E; Medhet, M, 2022)
"The current study investigated the prophylactic effect of ethyl pyruvate (EP) in Isoproterenol (ISO) - induced myocardial infarction (MI)."4.12Ethyl pyruvate attenuates isoproterenol-induced myocardial infarction in rats: Insight to TNF-α-mediated apoptotic and necroptotic signaling interplay. ( Ahmed, AAE; Al-Botaty, BM; Elkhoely, A; K El-Sayed, E, 2022)
"The present study investigated the cardioprotection of Indole-3-carbinol on isoproterenol (ISO)-induced myocardial infarction in Wistar rats."4.12Indole-3-carbinol ameliorated the isoproterenol-induced myocardial infarction via multimodal mechanisms in Wistar rats. ( Krishnamurthy, S; Ramakrishna, K, 2022)
" No studies were conducted earlier on the effects of (-) epicatechin (EC) on tachycardia, cardiac hypertrophy, and inflammation in MI."4.12Preventive effects of (-) epicatechin on tachycardia, cardiac hypertrophy, and nuclear factor- κB inflammatory signaling pathway in isoproterenol-induced myocardial infarcted rats. ( Ponnian, SMP, 2022)
"In vitro models of vasoconstriction, atrium, and in vivo models of invasive blood pressure measurement and isoproterenol (ISO) induced cardiac hypertrophy in rats were used to understand underlying mechanistic by LC-MS/MS based dynamic metabolomics analysis of the serum and heart samples to be investigated the effect of ethanolic extract of C."4.12Metabolomics based mechanistic insights to vasorelaxant and cardioprotective effect of ethanolic extract of Citrullus lanatus (Thunb.) Matsum. & Nakai. seeds in isoproterenol induced myocardial infraction. ( Ahmedah, HT; Al-Huqail, AA; Bigiu, N; Chicea, LM; Irimie, M; Marc Vlaic, RA; Moga, M; Pop, OL; Saqib, F; Wahid, M, 2022)
"Anethole may retain a cardio-protective potential by controlling myocardial oxidative stress (through Nrf2 pathway) and diminishing inflammation and apoptosis via the TLR4/MYD88 pathway."4.12Anethole's effects against myocardial infarction: The role of TLR4/NFκB and Nrf2/HO1 pathways. ( Mohamed, ME; Younis, NS, 2022)
" Rats were induced MI by isoproterenol (100 mg/kg body weight) and then treated with valencene and cardiac sensitive markers, cardiac hypertrophy, oxidative stress, markers of inflammation, nuclear factor- κB inflammatory pathway, and myocardial infarct size was estimated/determined."4.12Valencene post-treatment exhibits cardioprotection via inhibiting cardiac hypertrophy, oxidative stress, nuclear factor- κB inflammatory pathway, and myocardial infarct size in isoproterenol-induced myocardial infarcted rats; A molecular study. ( Berlin Grace, VM; Shervin Prince, S; Stanely Mainzen Prince, P, 2022)
"This study has explored the fact that geraniol prevents isoproterenol (ISO)-induced oxidative stress and inflammation-mediated myocardial infarction (MI) through enhanced expression of peroxiredoxin-1 (Prdx-1) in experimental animal models."4.12Geraniol enhances peroxiredoxin-1, and prevents isoproterenol-induced oxidative stress and inflammation associated with myocardial infarction in experimental animal models. ( Balupillai, A; David, E; Ranganathan, B; Saravanan, K; Wan, J; Zou, G, 2022)
" The present study was designed to investigate the cardioprotective effects of a newly synthesised coumarin, symbolised as 5,6-PhSHC, against cardiac remodelling process in isoproterenol (ISO) induced myocardial infarction (MI) in male Wistar rats by evaluating haematological, biochemical and cardiac biomarkers."4.12A novel synthetised sulphonylhydrazone coumarin (E)-4-methyl-N'-(1-(3-oxo-3H-benzo[f]chromen-2- yl)ethylidene)benzenesulphonohydrazide protect against isoproterenol-induced myocardial infarction in rats by attenuating oxidative damage, biological changes ( Abid, M; Abid, S; Allouche, N; Ammar, H; Baaziz, I; Elmufti, A; Feriani, A; Ghazouani, L; Hajji, R; Khdhiri, E; Mnafgui, K; Ramazani, A; Tlili, N; Zarei, A, 2022)
"Earlier studies reported that long-term treatment with thymoquinone (TQ) at a high dose (20 mg/kg) exerts a cardioprotective effect against isoproterenol (ISO)-triggered myocardial infarction (MI) in rats."4.12Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation. ( Agrawal, Y; Goyal, SN; Nagoor Meeran, MF; Nakhate, KT; Ojha, S; Patil, CR; Rathod, S; Sherikar, A, 2022)
" The present study evaluated the effectiveness of rosmarinic acid (RA) against myocardial infarction (MI) in comorbid depression induced by maternal separation in rats."4.12Evaluation of rosmarinic acid against myocardial infarction in maternally separated rats. ( Bhattacharjee, A; Nayak, PK; Shivavedi, N; Verma, H, 2022)
"This study aims to investigate the protective effects of thymoquinone (THQ) in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."4.12Thymoquinone regulates nitric oxide synthase enzymes and receptor-interacting serine-threonine kinases in isoproterenol-induced myocardial infarcted rats. ( Deger, N; Karabulut, D; Ozmen, R, 2022)
"In the present study, we assessed the therapeutic potential of Biochanin-A (BCA) (10 mg/kg BW/day) pretreatment for 30 days on lipid metabolic abnormalities, proinflammatory cytokines and matrix metalloproteinase expression in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."4.12Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats. ( Chandrasekaran, P; Jansy Isabella, RAR; Ponmurugan, P; Sangeethadevi, G; Saravanan, G; Sengottuvelu, S; V V, SU; Vadivukkarasi, S, 2022)
" The study was conducted to examine the ability of amniotic membrane mesenchymal stem cells (AMSCs) for protection against isoproterenol (ISO)-induced myocardial injury and attempted to show the possible mechanisms by which AMSCs that can be linked to inhibition of inflammation by targeting inflammatory MAPK/NF-κB pathway."4.12Human amniotic membrane mesenchymal stem cells exert cardioprotective effects against isoproterenol (ISO)-induced myocardial injury through suppression of inflammation and modulation of inflammatory MAPK/NF-κB pathway. ( Aboutaleb, N; Naseroleslami, M, 2022)
"The objective of the present paper is to formulate nanostructured lipid carriers (NLCs) of a calcium channel blocker, isradipine, to enhance its oral bioavailability and prolong its antihypertensive effect apart from evaluating efficacy of the formulation in isoproterenol induced myocardial infarction in rats."4.12Nanostructured lipid carriers of isradipine for effective management of hypertension and isoproterenol induced myocardial infarction. ( Alam, T; Ali, J; Ansari, MA; Baboota, S, 2022)
"The study explored the cardioprotective role of the methanolic leaf extract of Nelumbo nucifera and nuciferine against isoproterenol-induced myocardial infarction (MI) in Wistar rats."4.12Nuciferine from Nelumbo nucifera Gaertn. attenuates isoproterenol-induced myocardial infarction in Wistar rats. ( HarishKumar, R; Selvaraj, CI, 2022)
" Ten male NMRI mice were randomly divided into two groups: (1) control (healthy mice) and (2) myocardial infarction (MI)-induced model group (Isoproterenol/subcutaneously injection/single dose of 85 mg/kg)."4.02Cardiac aorta-derived extracellular matrix scaffold enhances critical mediators of angiogenesis in isoproterenol-induced myocardial infarction mice. ( Abdolmaleki, Z; Beheshtiha, SHS; Hosseinabadi, M, 2021)
" The current study has been designed to ascertain their effectiveness against Isoproterenol (ISO)-induced myocardial infarction (MI)."4.02Pharmacological evaluation of Vitis vinifera and Zingiber zerumbet on electrocardiographic, biochemical alterations and antioxidant status in isoproterenol-induced myocardial infarction in rats. ( Faisal, N; Hanif, M; Hassan Mehmood, M; Munir, I; Naseer, D, 2021)
"The present study demonstrated the protective effects of arbutin (ARB) on hyperlipidemia, mitochondrial, and lysosomal membrane damage and on the DNA damage in rats with isoproterenol (ISO)-induced myocardial infarction (MI)."4.02Arbutin prevents alterations in mitochondrial and lysosomal enzymes in isoproterenol-induced myocardial infarction: An in vivo study. ( Asaikumar, L; Sivasangari, S; Vennila, L, 2021)
"This study aimed to investigate the antihyperlipidemic and anti-inflammatory effect of zingiberene (ZBN) on isoproterenol-(ISO) induced myocardial infarction in rats."4.02Anti-inflammatory and anti-apoptotic effect of zingiberene on isoproterenol-induced myocardial infarction in experimental animals. ( Govindasamy, K; Li, J; Thangaiyan, R; Wei, J, 2021)
" This study investigated the therapeutic benefit of adding rosuvastatin to low-dose carvedilol in protection against myocardial infarction (MI)."4.02Rosuvastatin and low-dose carvedilol combination protects against isoprenaline-induced myocardial infarction in rats: Role of PI3K/Akt/Nrf2/HO-1 signalling. ( Awad, AS; Baraka, SA; El-Demerdash, E; El-Naga, RN; Elsherbini, DA; Tolba, MF, 2021)
"As rats develop myocardial infarction (MI) like lesions when injected with large doses of isoproterenol (ISO), this investigation was designed to evaluate the dose-dependent effects of thymoquinone (TQ) on ISO-induced myocardial injury in rats."4.02Thymoquinone dose-dependently attenuates myocardial injury induced by isoproterenol in rats via integrated modulations of oxidative stress, inflammation, apoptosis, autophagy, and fibrosis. ( Elhadidy, WF; Farag, MM; Khalifa, AA; Rashad, RM, 2021)
"The study provides the evidence of cardioprotective potentials of esculetin against isoproterenol induced myocardial infarction by antioxidant and myocardial membrane stabilization along with in vitro protection from arsenic induced ROS cell necrosis or apoptosis in H9C2 cells."4.02Exploring cardioprotective potential of esculetin against isoproterenol induced myocardial toxicity in rats: in vivo and in vitro evidence. ( G V, NK; Kedam, T; Nelson, VK; Pullaiah, CP; Rayapu, S, 2021)
" In the present study, we report that wogonin nanoparticles (Wog np) protect Isoproterenol (ISO) induced Myocardial Infarction (MI) rats."3.96Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction by moderating oxidative stress and inflammation. ( Bei, W; Chen, N; Jing, L, 2020)
"The current study enumerates the beneficial role of sciadopitysin (SDN) against isoproternol (ISO)-induced myocardial infarction (MI) in rats."3.96Protective Effect of Sciadopitysin against Isoproternol-Induced Myocardial Infarction in Rats. ( Cai, Y; Li, Y, 2020)
"Our study is aimed at evaluating the effects of pretreatment with Poly(lactic-co-glycolic) acid nanoparticle loaded with resveratrol (RSV PLGA NPs) compared to conventional resveratrol (RSV) on isoproterenol (ISO) induced myocardial infarction (MI) in rats."3.96Protective role of poly(lactic-co-glycolic) acid nanoparticle loaded with resveratrol against isoproterenol-induced myocardial infarction. ( Hu, Y; Kumar, P; Mishra, A; Moktan, JB; Sreeharsha, N; Sun, L; Wang, L, 2020)
"This study determined the effect of Biochanin A (BCA) on isoproterenol (ISO) induced Myocardial Infarction (MI) in male Wistar rats."3.96Therapeutic Potential of Biochanin-A Against Isoproterenol-Induced Myocardial Infarction in Rats. ( Govindasami, S; Raveendran, N; Sasikumar, V; Uddandrao, VVS, 2020)
"HC), a novel potent synthesized coumarin, on isoproterenol- (ISO-) induced myocardial infarction (MI) in rats."3.96(E)-N'-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis. ( Abid, S; Allouche, N; Ammar, H; Elmufti, A; Feriani, A; Ghazouani, L; Hajji, R; Khdhiri, E; Mnafgui, K; Tir, M; Tlili, N, 2020)
"The present study was aimed to discover novel pyrazole-thiadiazole derivatives as potent NF-ĸB inhibitor and its cardioprotective effect against isoproterenol (ISO)-induced myocardial infarction (MI) in rats."3.96Design and Development of Novel Pyrazole-Thiadiazole Derivatives as NF-ĸB Inhibitor and Cardioprotective Effect against Isoproterenol Induced Myocardial Infarction in Sprague-Dawley Rats. ( Guo, Y; Wang, J; Wu, X; Zhang, Y, 2020)
" Long non-coding RNA myocardial infarction associated transcript (LncMIAT) is closely related to heart disease, and here, we were the first to discover that LncMIAT may act as an miR-144 sponge in isoproterenol-induced cardiac hypertrophy."3.96The Expression of microRNA in Adult Rat Heart with Isoproterenol-Induced Cardiac Hypertrophy. ( Bai, L; Chen, L; Fan, Y; Gan, M; Guo, Z; Hao, X; Jiang, D; Li, X; Shen, L; Tan, Y; Zhang, S; Zhu, L, 2020)
" Isoproterenol was employed for acute myocardial infarction (AMI) and left ventricular hypertrophy (LVH) development and cardioprotective effects of Vt."3.96Ex vivo and in vivo studies of Viola tricolor Linn. as potential cardio protective and hypotensive agent: Inhibition of voltage-gated Ca ( Aslam, MA; Bobescu, E; Marceanu, L; Modhi, A; Moga, MA; Mujahid, K; Saqib, F, 2020)
" In this study, we investigated the preventive effect of alpha-pinene (AP), a monoterpene, against isoproterenol (ISO)-induced myocardial infarction and inflammation in Wistar rats."3.96Protective effect of alpha-pinene against isoproterenol-induced myocardial infarction through NF-κB signaling pathway. ( Cao, M; Wang, G; Wang, H; Wang, K; Yang, Z; Zhang, B; Zhao, Y, 2020)
"This research was aimed to explore protective effects of allicin on rat model of myocardial infarction via JNK signaling pathway."3.96Protective Effects of Allicin on ISO-Induced Rat Model of Myocardial Infarction via JNK Signaling Pathway. ( Li, EZ; Li, XP; Liu, YF; Ma, L; Wei, LN; Xu, W; Zhao, J, 2020)
" In particular, compound 4i was found to be the most potent ACE inhibitor and was further studied for cardioprotective effects against isoproterenol (ISO)-induced myocardial infarction (MI) in rats."3.96Novel thiazole-pyrazolone hybrids as potent ACE inhibitors and their cardioprotective effect on isoproterenol-induced myocardial infarction. ( Su, G; Su, X; You, H, 2020)
"The aim of this study was to evaluate the anti-ischemic effects of SAC through inhibiting neprilysin in isoproterenol (ISO) induced myocardial infarction (MI) in Wistar albino rats."3.91Sacubitril and valsartan protect from experimental myocardial infarction by ameliorating oxidative damage in Wistar rats. ( Akhtar, M; Akhtar, MS; Hassan, MQ; Imran, M; Najmi, AK; Rahman, O, 2019)
"This study was designed to investigate efficacy of Narirutin rich fraction (NRF), obtained from grape fruit peel, in the treatment of isoproterenol induced myocardial infarction in rats."3.91Attenuation of isoproterenol-induced cardiotoxicity in rats by Narirutin rich fraction from grape fruit. ( Barve, K; Bhatt, LK; Shaikh, S, 2019)
" Then, isoproterenol solution was used for induction of myocardial infarction."3.91The protective impact of betaine on the tissue structure and renal function in isoproterenol-induced myocardial infarction in rat. ( Babaei, G; Ghartavol, MM; Gholizadeh-Ghaleh Aziz, S; Hassan Khadem Ansari, M; Hossein Farjah, G, 2019)
" The investigation was conducted to evaluate the cardioprotective efficacy of RPG in rats having acute myocardial infarction (MI) induced by isoproterenol (ISO)."3.91Cardioprotective Effect of Rhapontigenin in Isoproterenol-Induced Myocardial Infarction in a Rat Model. ( Fan, Y, 2019)
"This study was designed to delineate the effect of kaempferol (KF) on heart failure (HF) in diabetic rats."3.91The protective effect of kaempferol on heart via the regulation of Nrf2, NF-κβ, and PI3K/Akt/GSK-3β signaling pathways in isoproterenol-induced heart failure in diabetic rats. ( Geng, J; Guo, Z; Han, S; Wang, Y; Zhang, L, 2019)
"In the present study, the modulatory effect of ursolic acid (UA) on cardiac fibrosis and mitochondrial and lysosomal enzymes activity in isoproterenol-induced myocardial infarction (MI) in rats were examined."3.91Ursolic acid modulates MMPs, collagen-I, α-SMA, and TGF-β expression in isoproterenol-induced myocardial infarction in rats. ( Pugalendi, KV; Radhiga, T; Senthil, S; Sundaresan, A, 2019)
" The present study aimed to elucidate the potential cardioprotective effect provided by ranolazine during myocardial infarction in nondiabetic and diabetic male rats."3.91Cardioprotective effect of ranolazine in nondiabetic and diabetic male rats subjected to isoprenaline-induced acute myocardial infarction involves modulation of AMPK and inhibition of apoptosis. ( Ameen, AM; Tawfik, MK, 2019)
" Our study is aimed at evaluating the effects of pretreatment with curcumin nanoparticles (CCNP) compared to conventional curcumin (CC) on isoproterenol (ISO) induced myocardial infarction (MI) in rats."3.91Effects of Curcumin Nanoparticles in Isoproterenol-Induced Myocardial Infarction. ( Boarescu, PM; Bocșan, IC; Bolboacă, SD; Bulboacă, AE; Chirilă, I; Gheban, D; Pop, RM, 2019)
"To evaluate the cardioprotective effects of the hydroalcoholic extract of the leaves of Alpinia zerumbet (AZE) against isoproterenol (ISO)-induced myocardial infarction in rats."3.91Cardioprotective effects induced by hydroalcoholic extract of leaves of Alpinia zerumbet on myocardial infarction in rats. ( Barros Ferreira, AK; Bortoluzzi, JH; da Silva, JCG; de Araújo-Júnior, JX; Ferreira Costa, CD; Nogueira Ribeiro, ÊA; Paulino, ET; Silva Júnior, EF; Smaniotto, S, 2019)
"Several researchers studied the protective effect of the N-acetylcysteine (NAC) when it was given before the induction of myocardial infarction (MI)."3.88Protective Role of N-Acetylcysteine on Isoprenaline-Induced Myocardial Injury: Histological, Immunohistochemical and Morphometric Study. ( Abdalla, IL; Kaooh, S; Mohamed, EA; Sadik, AOE; Zaki, SM, 2018)
"The objective of this study was to investigate the effect of astaxanthin on isoproterenol (ISO)-induced myocardial infarction and cardiac hypertrophy in rats."3.88Astaxanthin Prevented Oxidative Stress in Heart and Kidneys of Isoproterenol-Administered Aged Rats. ( Alam, MA; Alam, MN; Hossain, MM; Mamun, MAA; Rahman, MM; Reza, HM; Subhan, N; Ulla, A, 2018)
"Cardioprotective potential of aliskiren against isoproterenol-induced myocardial infarction was evaluated in this study."3.88Renin Inhibition by Aliskiren Protects Rats Against Isoproterenol Induced Myocardial Infarction. ( Akhtar, M; Hassan, MQ; Khan, V; Najmi, AK, 2018)
" Myocardial infarction was induced in Wistar rats via isoproterenol injection in a dose of (85 mg/kg, subcutaneously, twice at an interval of 24 h)."3.88Novel Mesenchymal Stem Cell Strategy in Alleviating Toll-Like Receptor-4, p53 and Nrf2 Signaling in Isoproterenol-Induced Myocardial Infarction in Rat Model. ( Abdel-Megeed, RM; Kadry, MO, 2018)
"The cardioprotective role of raspberry ketone (RK) against isoproterenol (ISO)-induced myocardial infarction (MI) in rats was assessed."3.88Raspberry ketone protects against isoproterenol-induced myocardial infarction in rats. ( Ali, SM; Bhandari, U; Haque, SE; Khan, V; Sharma, S, 2018)
" In this study, we have investigated the molecular mechanism of ER stress-mediated myocyte death in Isoproterenol (ISO) induced myocardial infarction and its inhibition by a potent anti oxidant and anti-apoptotic bioflavonoid, Vitexin."3.88Vitexin protects isoproterenol induced post myocardial injury by modulating hipposignaling and ER stress responses. ( Ashokkumar, R; Jamuna, S; Niranjali Devaraj, S; Sakeena Sadullah, MS, 2018)
"On the basis of preliminary studies and references of relevant literature about Sheng-Mai-San for myocardial ischemia, we chose three representative components (ginsenoside Rb1 (G), ruscogenin (R) and schisandrin (S)) for the optimization design studies."3.88A Strategy for Optimizing the Combination of Active Components Based on Chinese Medicinal Formula Sheng-Mai-San for Myocardial Ischemia. ( Chu, C; Fan, XX; Kou, JP; Li, F; Yu, BY; Zhang, Y, 2018)
" This study evaluated the cardioprotective effect of rosuvastatin on isoproterenol-induced myocardial infarction injury in rats."3.88Cardioprotective effect of rosuvastatin against isoproterenol-induced myocardial infarction injury in rats. ( Cang, J; Guo, K; Hu, Y; Jin, L; Yu, Y; Zhuang, Y, 2018)
"To investigate the effects and mechanisms of catalpol on cardiac function in rats with isoproterenol (ISO)-induced myocardial infarction (MI)."3.88Catalpol pretreatment attenuates cardiac dysfunction following myocardial infarction in rats. ( Bi, F; Sun, Q; Xu, Y, 2018)
" The present study was directed to investigate the effect of ATV pre- and post-treatment in isoproterenol (ISO)-induced cardiotoxicity in rats."3.88Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation. ( Ahmed, LA; Attalla, DM; Khattab, MM; Zaki, HF, 2018)
"This study examined the effects of aliskiren (Ali) (direct renin inhibitor) on serum cardiac enzymes (LDH and CK-MB), electrocardiography (ECG) changes, myocardial oxidative stress markers (MDA, CAT, and GSH) and the expression of Bcl2, HO-1, and Nrf2 genes in isoproterenol (ISO)-induced myocardial infarction (MI)."3.88Effects of low dose of aliskiren on isoproterenol-induced acute myocardial infarction in rats. ( Bin-Jaliah, I; Eid, EA; Hussein, AM; Sakr, HF, 2018)
"The effect of α-bisabolol on hemodyanimcs, lipid peroxidation, and nonenzymatic antioxidants was evaluated in isoproterenol-induced myocardial infarction in rats."3.88Protective effects of α-bisabolol on altered hemodynamics, lipid peroxidation, and nonenzymatic antioxidants in isoproterenol-induced myocardial infarction: In vivo and in vitro evidences. ( Al-Taee, H; Azimullah, S; Laham, F; Meeran, MFN; Ojha, S, 2018)
"The present study was designed to investigate the protective effect of ferulic acid (FA) against isoproterenol (ISO)-induced cardiac toxicity in rats."3.88Cardioprotective role of FA against isoproterenol induced cardiac toxicity. ( Jain, PG; Mahajan, UB; Shinde, SD; Surana, SJ, 2018)
" This study was performed to investigate the effects of syrigaldehyde (SYD), a phytochemical against isoproterenol (ISO) induced cardiotoxicity model."3.88Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats. ( Akhtar, K; Mateen, S; Moin, S; Mubeena Mariyath, PM; Naeem, SS; Rizvi, W; Shahzad, S, 2018)
" Isoproterenol (ISO)-induced cardiotoxicity challenged mice were treated with NY for 28 days at two doses (0."3.88Nanoyttria attenuates isoproterenol-induced cardiac injury. ( Godugu, C; Khurana, A; Kumari, P, 2018)
"We substantiated the role of peroxisome proliferator-activated receptor-γ (PPAR-γ) activation in the protective effect of apigenin against the myocardial infarction (MI) in diabetic rats."3.85The Protective Effect of Apigenin on Myocardial Injury in Diabetic Rats mediating Activation of the PPAR-γ Pathway. ( Agrawal, YO; Arya, DS; Chandrayan, G; Goyal, SN; Mahajan, UB; Ojha, S; Patil, CR; Suchal, K, 2017)
" Therefore, the current investigation was intended to evaluate the effect of malvidin against myocardial infarction induced by isoproterenol in the rats."3.85Cardioprotective Effects of Malvidin Against Isoproterenol-Induced Myocardial Infarction in Rats: A Mechanistic Study. ( Cheng, LX; Jiang, LL; Li, H; Peng, YD; Wan, SP; Wei, H; Zeng, QT, 2017)
"The present study investigated the protective effect of diethylcarbamazine in inhibiting nuclear factor (NF)-κB activation in isoproterenol‑induced acute myocardial infarction (AMI) rats through the poly ADP ribose polymerase (PARP) pathway."3.85Protective effect of diethylcarbamazine inhibits NF-κB activation in isoproterenol-induced acute myocardial infarction rat model through the PARP pathway. ( Jia, G; Liu, X; Zao, M, 2017)
", family Arecaceae) on isoproterenol-induced myocardial infarction (MI) in rats."3.85Cardiopreventive effect of ethanolic extract of Date Palm Pollen against isoproterenol induced myocardial infarction in rats through the inhibition of the angiotensin-converting enzyme. ( Abid, L; Ayadi, F; Belbahri, L; Ben Amar, R; Ben Mefteh, F; Daoud, A; ElFeki, A; Gharsallah, N; Jmal, S; Kadri, A; Mnafgui, K; Rateb, ME; Turki, M, 2017)
"The present study was designed to evaluate the cardioprotective effects of nesfatin-1, a novel peptide with anorexigenic properties, in rats with isoproterenol (ISO)-induced myocardial infarction (MI), and to further investigate the role of Akt/GSK-3β signaling pathway in the protective effect of nesfatin-1."3.85Cardioprotective effect of nesfatin-1 against isoproterenol-induced myocardial infarction in rats: Role of the Akt/GSK-3β pathway. ( Adiguzel, D; Barutcigil, A; Celik-Ozenci, C; Dalaklioglu, S; Kuscu, N; Ozdem, S; Tasatargil, A, 2017)
"Cardioprotective potential of anthocyanin rich red cabbage extract (ARCE) was assessed in H2O2 treated rat neonatal cardiomyoblasts (H9c2 cells) and isoproterenol (ISO) induced rodent model of myocardial infarction."3.85Anthocyanin rich extract of Brassica oleracea L. alleviates experimentally induced myocardial infarction. ( Das, S; Devkar, R; Jana, S; Mandal, R; Patel, D; Patel, S; Thadani, J; Upadhyay, K, 2017)
" macroptera peel and pulp against isoproterenol (ISO)-induced myocardial infarction (MI) in rats."3.85Protective effects of ethanolic peel and pulp extracts of Citrus macroptera fruit against isoproterenol-induced myocardial infarction in rats. ( Afroz, R; Das, S; Gan, SH; Hossain, MS; Hossen, MS; Ibrahim Khalil, M; Islam, MA; Paul, S; Saha, M; Tanvir, EM, 2017)
" The objective of present study is to find out the cardioprotective activity and to explore the underlying mechanisms of quercetin pretreatment (50 mg/kg body weight, orally) for 14 days against isoproterenol (ISO; 100 mg/kg body weight, subcutaneously) induced myocardial infarction in Wistar rats."3.85Molecular and biochemical evidence on the protective effects of quercetin in isoproterenol-induced acute myocardial injury in rats. ( Bodduluru, LN; Kasala, ER; Kumar, M; Kumar, V; Lahkar, M, 2017)
"The present study aimed to investigate the cardioprotective effect of hydroxytyrosol (HT) against isoproterenol-induced myocardial infarction in rats."3.83Protective Effect of Hydroxytyrosol Against Cardiac Remodeling After Isoproterenol-Induced Myocardial Infarction in Rat. ( Allouche, N; Derbali, F; Elfeki, A; Ellefi, H; Gharsallah, N; Hajji, R; Khlif, I; Kraiem, F; Mnafgui, K, 2016)
" The current study evaluated the consequence of AP in isoproterenol (ISO)-induced oxidative stress and myocardial infarction during β-adrenergic receptor stimulus in rats by persistent hemodynamic, biochemical and histopathological changes."3.83Apigenin Attenuates β-Receptor-Stimulated Myocardial Injury Via Safeguarding Cardiac Functions and Escalation of Antioxidant Defence System. ( Buwa, CC; Goyal, SN; Mahajan, UB; Patil, CR, 2016)
"This study aimed to evaluate the antithrombotic, anti-inflammatory and anti-cardiac remodeling properties of eugenol in isoproterenol-induced myocardial infarction in rats."3.83Anti-inflammatory, Antithrombotic and Cardiac Remodeling Preventive Effects of Eugenol in Isoproterenol-Induced Myocardial Infarction in Wistar Rat. ( Allouche, N; Derbali, F; Ellefi, H; Gammoudi, A; Gharsallah, N; Hajji, R; Kadri, A; Khabbabi, G; Mnafgui, K, 2016)
"The current study investigated the combinatorial effect of pravastatin (PRAV) and bone marrow mononuclear cells (BM-MNC) on acute myocardial infarction (AMI) induced experimentally in rats."3.83Bone marrow mononuclear cells enhance anti-inflammatory effects of pravastatin against isoproterenol-induced myocardial infarction in rats. ( El-Desouky, KI; El-Mahdy, N; El-Sayad, M; Salem, ML; Zaghow, N, 2016)
"Mitochondrial dysfunction has been suggested to be one of the important pathological events in isoproterenol (ISO), a synthetic catecholamine and β-adrenergic agonist induced myocardial infarction (MI)."3.83Thymol, a dietary monoterpene phenol abrogates mitochondrial dysfunction in β-adrenergic agonist induced myocardial infarcted rats by inhibiting oxidative stress. ( Jagadeesh, GS; Nagoor Meeran, MF; Selvaraj, P, 2016)
"In the present study, we investigated whether combination therapy of low-dose benidipine with the potent free radical scavenger edaravone has a cardioprotective effect against isoproterenol (ISO)-induced myocardial infarction (MI) in Wistar rats."3.83Edaravone, a potent free radical scavenger and a calcium channel blocker attenuate isoproterenol induced myocardial infarction by suppressing oxidative stress, apoptotic signaling and ultrastructural damage. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2016)
"This study evaluates the protective effects of 7-hydroxycoumarin (7-HC) on dyslipidemia and cardiac hypertrophy in isoproterenol (ISO) induced myocardial infarction (MI) in rats."3.83Protective Effects of 7-Hydroxycoumarin on Dyslipidemia and Cardiac Hypertrophy in Isoproterenol-Induced Myocardial Infarction in Rats. ( Jagadeesh, GS; Nagoor Meeran, MF; Selvaraj, P, 2016)
"Subcutaneous injection of isoproterenol (85 mg/kg) on last 2 consecutive days in per se group and 7 days treatment of different groups at 24 h interval induced myocardial infarction in Wistar rats."3.83Histamine H3 Receptor Agonist Imetit Attenuated Isoproterenol Induced Renin Angiotensin System and Sympathetic Nervous System Overactivity in Myocardial Infarction of Rats. ( Akhtar, M; Hass, C; Khanam, R; Najmi, AK; Panda, BP, 2016)
" The present study was designed to investigate the protective effect of PDSS on isoproterenol (ISO)-induced myocardial infarction in rats and to elucidate the potential mechanism."3.83Paeonol and danshensu combination attenuates apoptosis in myocardial infarcted rats by inhibiting oxidative stress: Roles of Nrf2/HO-1 and PI3K/Akt pathway. ( Chen, Y; Dong, QQ; Duan, LR; Li, H; Sheng, JJ; Song, F; Wang, SW; Xie, YH; Yang, Q; Zhang, BL, 2016)
"The present study investigates the cardioprotective activity of the Macrotyloma uniflorum seed extract (MUSE) and its phenolic acids (p-coumaric acid and ferulic acid) in isoproterenol (ISO)-induced myocardial infarction in rats."3.83Dietary Phenolic Acids of Macrotyloma uniflorum (Horse Gram) Protect the Rat Heart Against Isoproterenol-Induced Myocardial Infarction. ( Laddha, A; Nandave, M; Panda, V; Srinath, S, 2016)
" This work investigated the protective effect of pioglitazone on myocardial infarction (MI) in non-diabetic and diabetic rats, focusing on its role on advanced glycated endproducts (AGEs) and cardiac apoptotic machinery."3.83Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis. ( Farag, NE; Khodeer, DM; Moustafa, YM; Zaitone, SA, 2016)
" This study investigated the combined effect of low doses of fenofibrate and rosuvastatin in isoproterenol-induced experimental myocardial infarction."3.83Chronic oral administration of low-dose combination of fenofibrate and rosuvastatin protects the rat heart against experimentally induced acute myocardial infarction. ( Balakumar, P; Garg, M; Kalra, S; Khanna, D, 2016)
"The present study was designed to investigate the cardioprotective effects of Sundarban honey (SH) in rats with isoproterenol- (ISO-) induced myocardial infarction."3.83Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats. ( Afroz, R; Alam, N; Gan, SH; Hossain, MS; Karim, N; Khalil, MI; Tanvir, EM, 2016)
" In this paper, the mediation of XKS on the isoproterenol (ISO)-induced myocardial infarction (MI) rat were evaluated based on a tissue-targeted metabonomics in vitro/vivo."3.83Standardized Chinese Formula Xin-Ke-Shu inhibits the myocardium Ca(2+) overloading and metabolic alternations in isoproterenol-induced myocardial infarction rats. ( Chang, X; Jia, HM; Liu, YT; Zhou, C; Zou, ZM, 2016)
"Intent of the present study has been made to appraise the cardioprotective effect of chlorogenic acid (CGA) on isoproterenol (ISO) induced myocardial infarction (MI) in male albino Wistar rats."3.83Chlorogenic acid a dietary polyphenol attenuates isoproterenol induced myocardial oxidative stress in rat myocardium: An in vivo study. ( Akila, P; Vennila, L, 2016)
"In this study, the ability of KMP to protect heart against isoproterenol (ISO) induced oxidative stress and myocardial infarction was evaluated."3.83Kampeferol protects against oxidative stress and apoptotic damage in experimental model of isoproterenol-induced cardiac toxicity in rats. ( Arya, DS; Bhatia, J; Gamad, N; Goyal, SN; Malhotra, RK; Malik, S; Suchal, K, 2016)
"The effects of benidipine on oxidative stress and myocardial apoptosis were assessed in isoproterenol (ISO)-induced myocardial infarction (MI) in wistar rats."3.81Benidipine prevents oxidative stress, inflammatory changes and apoptosis related myofibril damage in isoproterenol-induced myocardial infarction in rats. ( Akhtar, M; Akhtar, MS; Ali, J; Ansari, SH; Haque, SE; Hassan, MQ; Najmi, AK, 2015)
" Therefore because oxidative stress plays a significant role in the pathophysiology of myocardial infarction (MI), the aim of our study was to investigate whether hydrogen-rich saline has cardioprotective effects against isoproterenol-induced MI in rats."3.81Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats. ( Han, JJ; Jing, L; Qin, SC; Sun, XJ; Wang, Y; Zhao, B; Zhao, XM, 2015)
"This study was aimed to evaluate the preventive role of phytic acid on lysosomal enzymes in isoproterenol (ISO)-induced myocardial infarction (MI) in male Wistar rats."3.81Preventive effect of phytic acid on lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats. ( Brindha, E; Rajasekapandiyan, M, 2015)
" alata (LPva) in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."3.81Protective effects of Labisia pumila var. alata on biochemical and histopathological alterations of cardiac muscle cells in isoproterenol-induced myocardial infarction rats. ( Amran, AZ; Dianita, R; Jalil, J; Jantan, I, 2015)
"The present study evaluates the protective effect of the standardized extract of ginger against isoproterenol (ISO)-induced myocardial infarction (MI) in rats."3.81Protective effects of the standardized extract of Zingiber officinale on myocardium against isoproterenol-induced biochemical and histopathological alterations in rats. ( Amran, AZ; Buang, F; Dianita, R; Jantan, I, 2015)
"The present study was designed to evaluate the cardioprotective potential of edaravone on oxidative stress, anti-apoptotic, anti-inflammatory and ultrastructure findings in isoproterenol (ISO) induced myocardial infarction (MI) in rats."3.81Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence. ( Akhtar, M; Akhtar, MS; Ali, J; Haque, SE; Hassan, MQ; Najmi, AK, 2015)
"The present study was designed to evaluate the cardioprotective effect of Tunisian flaxseed oil (Linum usitatissimum) against isoproterenol-induced myocardial infarction in rats by studying hypertensive and cardiac damage markers especially electrocardiographic changes and troponin T serum level."3.81Cardioprotective effect of linseed oil against isoproterenol-induced myocardial infarction in Wistar rats: a biochemical and electrocardiographic study. ( Affes, M; Allouche, N; Derbali, A; Derbali, F; El Feki, A; Gharsallah, N; Hajji, R; Mnafgui, K, 2015)
"Oleuropein offers high preventive effects from cardiac remodeling process in rats with acute myocardial infarction."3.81Preventive effects of oleuropein against cardiac remodeling after myocardial infarction in Wistar rat through inhibiting angiotensin-converting enzyme activity. ( Allouche, N; Derbali, F; Elfeki, A; Ellefi, H; Gharsallah, N; Hajji, R; Halabalaki, M; Khlif, I; Kraiem, F; Michel, T; Mnafgui, K; Skaltsounis, AL, 2015)
"The present study was designed to investigate the cardioprotective effects of Malaysian Tualang honey against isoproterenol- (ISO-) induced myocardial infarction (MI) in rats by investigating changes in the levels of cardiac marker enzymes, cardiac troponin I (cTnI), triglycerides (TG), total cholesterol (TC), lipid peroxidation (LPO) products, and antioxidant defense system combined with histopathological examination."3.81Cardioprotective Effects of Tualang Honey: Amelioration of Cholesterol and Cardiac Enzymes Levels. ( Afroz, R; Gan, SH; Khalil, MI; Sulaiman, SA; Tanvir, EM, 2015)
"The present study was carried out to evaluate the protective effect of different statins on isoproterenol (ISO) induced myocardial necrosis."3.81Comparative evaluation of HMG CoA reductase inhibitors in experimentally-induced myocardial necrosis: Biochemical, morphological and histological studies. ( Gandhi, HP; Patel, SS; Rathod, SP; Trivedi, JI; Variya, BC, 2015)
"In this study, we investigated the cardioprotective effect of one purified polysaccharide (SMP1) from Salvia miltiorrhiza on isoproterenol (ISO)-induced myocardial infarction (MI) in rats."3.81Protective effect of a polysaccharide from Salvia miltiorrhiza on isoproterenol (ISO)-induced myocardial injury in rats. ( Geng, ZH; Huang, L; Song, MB; Song, YM, 2015)
"The aim of the present study was to investigate the cardioprotective effects of Timosaponin B II (TB), a main bioactive constituent from Anemarrhenae asphodeloides Bge, on an isoproterenol (ISO)-induced myocardial infarction model in rats and explore its underlying mechanisms."3.81Cardioprotective effects of timosaponin B II from Anemarrhenae asphodeloides Bge on isoproterenol-induced myocardial infarction in rats. ( Chen, JJ; Deng, XY; Fu, Q; Li, HY; Ma, SP; Ma, ZQ, 2015)
" Myocardial infarction was induced by isoproterenol (ISP) (65 mg/kg) and confirmed by biochemical, electrophysiological and histopathological methods."3.81Anti-platelet effects of nimesulide in isoproterenol-induced myocardial ischaemia and infarction in rabbits. ( Ahmed, S; Dima, L; Gul, S; Moga, M; Ze Jaafar, H; Zia-Ul-Haq, M, 2015)
"We investigated the protective role of Withania somnifera leaf extract (WSLEt) on isoproterenol- (ISO-) induced myocardial infarction (MI) in rats."3.81Amelioration of Isoproterenol-Induced Oxidative Damage in Rat Myocardium by Withania somnifera Leaf Extract. ( Afroz, R; Ahmed, R; Ahmmed, I; Alam, N; Gan, SH; Khalil, MI; Paul, S; Tanvir, EM, 2015)
" The current study investigated the effect of cardamom on hemodynamic, biochemical, histopathological and ultrastructural changes in isoproterenol (ISO)-induced myocardial infarction."3.81Protective Effects of Cardamom in Isoproterenol-Induced Myocardial Infarction in Rats. ( Agrawal, YO; Arya, DS; Goyal, SN; Kumari, S; Mahajan, UB; Ojha, S; Patil, CR; Sharma, C, 2015)
" In this study, we investigated whether baicalin ameliorates isoproterenol-induced acute myocardial infarction and its mechanism."3.81Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat. ( Chen, H; Ruan, H; Wang, J; Xu, Y; Zhao, W, 2015)
"Myocardial infarction (MI) was induced by subcutaneous injection of isoproterenol (ISO) to investigate the effect of ISO on Coenzyme Q10 (CoQ10) content of myocardium and subsequent effects on lipid peroxidation, electrocardiogram pattern and hemodynamic parameters of the rat's heart."3.80Reduction of coenzyme q10 content: a possible effect of isoproterenol on heart failure and myocardial infarction in rat. ( Andalib, S; Garjani, A; Ghanbarzadeh, S; Khorrami, A, 2014)
" This study evaluated the protective effect of XKS against isoproterenol (ISO)-induced myocardial infarction (MI)."3.80Metabolic pathways involved in Xin-Ke-Shu protecting against myocardial infarction in rats using ultra high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. ( Cai, DY; Chang, X; Cheng, WH; Ding, G; Jia, HM; Liu, YT; Zhang, HW; Zhao, X; Zou, ZM, 2014)
"The present study was designed to evaluate the cardioprotective potential of water extract of rhizomes of Acorus gramineus (AGR) against isoproterenol (ISO)-induced myocardial infarction."3.80Cardioprotective effect of rhizomes of Acorus gramineus against isoproterenol-induced cardiac damage in pigs. ( Antonisamy, P; Bae, H; Chung, HS; Kim, JH; Lee, SR, 2014)
" The aim of the present study was to investigate the effects of OxLDL on electrocardiogram and hemodynamic parameters of rat's heart in isoproterenol (ISO)-induced myocardial infarction (MI) model."3.80Effects of LDL and oxidized LDL on cardiac function in isoproterenol-induced myocardial infarction in rat. ( Andalib, S; Arami, S; Garjani, A; Ghanbarzadeh, S; Khorrami, A; Maleki-Dizaji, N; Ziaee, M, 2014)
" The present study was designed to evaluate the cardioprotective potential of RG against isoproterenol (ISO)-induced myocardial infarction (MI), by assessing electrocardiographic, hemodynamic, and biochemical parameters."3.80Red ginseng (Panax ginseng) decreases isoproterenol-induced cardiac injury via antioxidant properties in porcine. ( Bae, BS; Cho, JY; Kim, B; Kim, JH; Lim, KH, 2014)
" This study investigated the cardioprotective effect and possible mechanism of embelin, a major constituent of Embelia ribes Burm, using isoproterenol (ISO)-induced myocardial infarction model in rats."3.80Cardioprotective effect of embelin on isoproterenol-induced myocardial injury in rats: possible involvement of mitochondrial dysfunction and apoptosis. ( Anubolu, H; Koneru, M; Kumar, JM; Kuncha, M; Rachamalla, SS; Sahu, BD; Sistla, R, 2014)
"Acute treatment with metformin has a protective effect in myocardial infarction by suppression of inflammatory responses due to activation of AMP-activated protein kinase (AMPK)."3.80Chronic treatment with metformin suppresses toll-like receptor 4 signaling and attenuates left ventricular dysfunction following myocardial infarction. ( Clanachan, AS; Garjani, A; Ghazi-Khansari, M; Maleki-Dizaji, N; Rameshrad, M; Soraya, H, 2014)
"Rats were injected with isoproterenol (ISO; 110 mg/kg, ip, 2 doses, 24 h interval) to induce acute myocardial infarction (AMI) and were sacrificed 6 and 24 h after the last ISO injection."3.80Effects of carnosine on prooxidant-antioxidant status in heart tissue, plasma and erythrocytes of rats with isoproterenol-induced myocardial infarction. ( Develi, S; Doğru-Abbasoğlu, S; Evran, B; Kalaz, EB; Karpuzoğlu, H; Olgaç, V; Soluk-Tekkeşin, M; Uysal, M, 2014)
" Most importantly, we found that epicardial application of resiniferatoxin largely prevented the elevated left ventricle end-diastolic pressure, lung edema, and cardiac hypertrophy, partially reduced left ventricular dimensions in the failing heart, and increased cardiac contractile reserve in response to β-adrenergic receptor stimulation with isoproterenol in CHF rats."3.80Cardiac sympathetic afferent denervation attenuates cardiac remodeling and improves cardiovascular dysfunction in rats with heart failure. ( Cornish, KG; Rozanski, GJ; Wang, HJ; Wang, W; Zucker, IH, 2014)
" The other 32 rats were subjected to induction of hypercholesterolemia by high-fat diet for 3 weeks, followed by induction of AMI by subcutaneous injections of isoproterenol (85 mg/kg/day, for 2 days)."3.80Assessment of the prophylactic role of aspirin and/or clopidogrel on experimentally induced acute myocardial infarction in hypercholesterolemic rats. ( El-Hadidy, WF; Mannaa, HF; Mohamed, AR, 2014)
"The preventive effects of (-) epicatechin on oxidative stress, cardiac mitochondrial damage, altered membrane bound adenosine triphosphatases and minerals were reported previously in isoproterenol-induced myocardial infarction model."3.79(-) Epicatechin prevents alterations in lysosomal glycohydrolases, cathepsins and reduces myocardial infarct size in isoproterenol-induced myocardial infarcted rats. ( Prince, PS, 2013)
" Herein, we examined the effects of this peptide on isoproterenol (ISO)-induced cardiac remodeling and myocardial infarction (MI) injury."3.79The novel Mas agonist, CGEN-856S, attenuates isoproterenol-induced cardiac remodeling and myocardial infarction injury in rats. ( Almeida, AP; Beiman, M; Carvalho, MB; Cohen, Y; Cojocaru, G; Ferreira, AJ; Ianzer, D; Marques, FD; Peluso, AA; Rotman, G; Santos, RA; Savergnini, SQ; Silva, GA, 2013)
" Rats were pretreated with p-coumaric acid (8 mg/kg body weight) daily for a period of 7 days and then injected with isoproterenol (100mg/kg body weight) on 8th and 9th day to induce myocardial infarction."3.79Preventive effects of p-coumaric acid on cardiac hypertrophy and alterations in electrocardiogram, lipids, and lipoproteins in experimentally induced myocardial infarcted rats. ( Roy, AJ; Stanely Mainzen Prince, P, 2013)
"This study was aimed to evaluate the preventive effect of diosgenin and exercise on tissue antioxidant status in isoproterenol-induced myocardial infarction (MI) in male Wistar rats."3.79Preconditioning with diosgenin and treadmill exercise preserves the cardiac toxicity of isoproterenol in rats. ( Mohammadi, M; Rashidi, B; Salimeh, A, 2013)
"The present study was designed to evaluate the cardioprotective potential of lycopene (LCP) against isoproterenol (ISP)-induced myocardial infarction (MI), by assessing hemodynamic, biochemical and histopathological parameters."3.79Cardioprotective effect of lycopene against isoproterenol-induced myocardial infarction in rats. ( Arora, S; Arya, DS; Goyal, S; Kumari, S; Ojha, S; Sharma, C, 2013)
" This study aims to evaluate the protective effects of sinapic acid on cardiac hypertrophy, dyslipidaemia and alterations in lipoproteins and electrocardiogram in isoproterenol-induced myocardial infarcted rats."3.79Protective effects of sinapic acid on cardiac hypertrophy, dyslipidaemia and altered electrocardiogram in isoproterenol-induced myocardial infarcted rats. ( Mainzen Prince, PS; Roy, SJ, 2013)
"The present study was designed to investigate the cardioprotective effect of neferine against isoproterenol-induced myocardial infarction."3.79Protective effect of neferine against isoproterenol-induced cardiac toxicity. ( Archanah, A; Lalitha, G; Padma, VV; Poornima, P, 2013)
" In the present study, we evaluated the effects of metformin on cardiac function, hemodynamic parameters, and histopathological changes in isoproterenol-induced myocardial infarction (MI)."3.78Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats. ( Garjani, A; Khorrami, A; Maleki-Dizaji, N; Soraya, H, 2012)
"Vitamin A is beneficial in counteracting free radical damage, therefore the present study is designed to investigate the effect of vitamin A against isoproterenol-induced myocardial infarction in rats."3.78Cardio protective effect of vitamin A against isoproterenol-induced myocardial infarction. ( Pipaliya, H; Vaghasiya, J, 2012)
"To assess the protective effects of lycopene on electrocardiographic, hemodynamic, biochemical and apoptotic changes in isoproterenol induced myocardial infarction."3.78Tomato lycopene attenuates myocardial infarction induced by isoproterenol: electrocardiographic, biochemical and anti-apoptotic study. ( Aman, U; Balaraman, R; Vaibhav, P, 2012)
" The present study was evaluated to investigate whether pyruvate attenuates the development of cardiotoxicity in isoproterenol (ISO)-induced myocardial infarction by assessing hemodynamic, biochemical and histopathological parameters."3.78Pyruvate attenuates cardiac dysfunction and oxidative stress in isoproterenol-induced cardiotoxicity. ( Arya, DS; Goyal, S; Kumari, S; Ojha, S, 2012)
" We examined the effect of Se on LTB(4) synthesis during isoproterenol (ISP)-induced myocardial infarction (MI) in rats."3.78Impact of selenium on the leukotriene B4 synthesis pathway during isoproterenol-induced myocardial infarction in experimental rats. ( John, F; M, I; Panicker, S; Swathy, SS, 2012)
"The aim of this investigation was to evaluate the preventive role of morin, a flavonoid, on cardiac marker enzymes such as aspartate transaminase, lactate dehydrogenase, creatine kinase and creatine kinase-MB, membrane-bound enzymes such as sodium potassium-dependent adenosine triphosphatase, calcium-dependent adenosine triphosphatase and magnesium-dependent adenosine triphosphatase, and glycoproteins such as hexose, hexosamine, fucose and sialic acid in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."3.78Pretreatment with morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol-induced myocardial infarction in rats. ( Al-Numair, KS; Alsaif, MA; Chandramohan, G, 2012)
"Following induction of acute myocardial infarction in rats by adminstration of isoproterenol, hemodynamic and electrocardiographic parameters were monitored and recorded continuously, cardiac enzymes and parameters of oxidative stress were measured, and histopathological examination of heart tissue was performed."3.78Cardioprotective effect of water and ethanol extract of Salvia miltiorrhiza in an experimental model of myocardial infarction. ( Chao, RB; Du, JR; He, LF; Li, YJ; Shen, Y; Zhou, R, 2012)
"Cardiac hypertrophy was induced by a chronic infusion of isoproterenol (ISO) 15 mg/kg/day for 3 weeks in human apoB transgenic mice (n = 9) and in non-transgenic wild-type mice (n = 10)."3.78Overexpression of apolipoprotein B attenuates pathologic cardiac remodeling and hypertrophy in response to catecholamines and after myocardial infarction in mice. ( Borén, J; Lindbom, M; Omerovic, E; Råmunddal, T; Shao, Y; Täng, MS, 2012)
"The present study was designed to evaluate the protective effect of ursolic acid (UA) against isoproterenol-induced myocardial infarction."3.78Effect of ursolic acid treatment on apoptosis and DNA damage in isoproterenol-induced myocardial infarction. ( Ezhumalai, M; Pugalendi, KV; Radhiga, T; Rajamanickam, C; Sundaresan, A, 2012)
"In this study, the effects of lacidipine (LAC), ramipril (RAM), and valsartan (VAL) on biochemical and histopathologic changes in heart tissue were studied in rats with isoproterenol-induced (ISO-induced) myocardial infarction (MI)."3.78Comparing effects of lacidipine, ramipril, and valsartan against experimentally induced myocardial infarcted rats. ( Albayrak, A; Bayir, Y; Ferah, I; Halici, Z; Kabalar, E; Karakus, E; Keles, MS; Keles, O; Unal, B, 2012)
"This study was designed to evaluate the anti-inflammatory and anti-apoptotic effects of the alcoholic extract of the berries of Crataegus oxyacantha (AEC), a medicinal herb, on isoproterenol-induced myocardial infarction (MI) in a rat model."3.78Anti-inflammatory and anti-apoptotic effects of Crataegus oxyacantha on isoproterenol-induced myocardial damage. ( Devaraj, SN; Thiruchenduran, M; Vijayan, NA, 2012)
"The present investigation was to evaluate the antioxidant, biochemical profile and histological studies of qualitatively standardized ethanolic extract of Terminalia pallida fruits (TpFE) against isoproterenol-induced myocardial infarction in rats."3.78Cardioprotective effect of HPLC standardized ethanolic extract of Terminalia pallida fruits against isoproterenol-induced myocardial infarction in albino rats. ( Abdul Kareem, M; Lakshmi Devi, K; Rasool, SN; Saayi Krushna, G; Shaik, AH; Vikram Kumar Reddy, A, 2012)
"Myocardial infarction was produced in rats with 85 mgkg(-1) isoproterenol administered subcutaneously twice at an interval of 24 h."3.78Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats. ( Du, GH; Fang, LH; Gong, LL; Li, XX; Qin, HL; Sun, JL; Wang, SB, 2012)
" Physical training was considered a physiological condition, while isoproterenol-induced hypertrophy, myocardial infarction and DOCA-salt model of hypertension were used as pathological models of heart injury."3.78The cardiac expression of Mas receptor is responsive to different physiological and pathological stimuli. ( Almeida, PW; Braga, VB; Campagnole-Santos, MJ; Coutinho, DC; Dias-Peixoto, MF; Ferreira, AJ; Gomes Filho, A; Greco, L; Guatimosim, S; Lima, RF; Melo, DS; Melo, MB; Santos, RA, 2012)
" The present study reveals the protective role of ellagic acid in biochemical parameters including serum iron, plasma iron binding capacity, uric acid, glycoprotein, and electrolytes along with hematological parameters."3.78Protective efficacy of ellagic acid on glycoproteins, hematological parameters, biochemical changes, and electrolytes in myocardial infarcted rats. ( Kannan, MM; Quine, SD; Sangeetha, T, 2012)
" The activation of AMPK by metformin prevents cardiac remodeling after myocardial infarction (MI)."3.78Short-term treatment with metformin suppresses toll like receptors (TLRs) activity in isoproterenol-induced myocardial infarction in rat: are AMPK and TLRs connected? ( Banani, A; Farajnia, S; Garjani, A; Khani, S; Khorrami, A; Maleki-Dizaji, N; Rameshrad, M; Soraya, H, 2012)
" The present study was designed to investigate the cardioprotective effects of paeonol and danshensu (representative active ingredient of Cortex Moutan and Radix Salviae Milthiorrhizae, respectively) on isoproterenol-induced myocardial infarction in rats and its underlying mechanisms."3.78Cardioprotective effect of paeonol and danshensu combination on isoproterenol-induced myocardial injury in rats. ( Bi, LL; Cao, W; Hu, J; Li, H; Miao, S; Qiu, PC; Sun, JY; Wang, JB; Wang, SW; Xie, YH; Yang, Q; Zhang, BL; Zhou, XX, 2012)
"The protective effect of aspartate and glutamate in isoproterenol induced myocardial infarction (MI) was investigated in experimental animals."3.77Aspartate and glutamate prevents isoproterenol-induced cardiac toxicity by alleviating oxidative stress in rats. ( Babu, PV; Shyamaladevi, CS; Sivakumar, R, 2011)
"The present study evaluated the protective potential of aqueous extract of Oxalis corniculata (OCE) against isoproterenol (ISO) induced myocardial infarction in rats."3.77Cardioprotective effects of aqueous extract of Oxalis corniculata in experimental myocardial infarction. ( Abhilash, PA; Lijo Cherian, O; Nampoothiri, SV; Nisha, P; Prathapan, A; Raghu, KG; Sunitha, TK, 2011)
"To develop a rat model of myocardial infarction induced by isoproterenol (ISO)."3.77Time-dependent responses of rat troponin I and cardiac injury following isoproterenol administration. ( Hasić, S; Jadrić, R; Kiseljaković, E; Mornjaković, Z; Valjevac, A; Winterhalter-Jadrić, M, 2011)
"The present study was designed to evaluate the cardioprotective effects of ellagic acid against isoproterenol induced myocardial infarction in rats by studying electrocardiography, blood pressure, cardiac markers, lipid peroxidation, antioxidant defense system and histological changes."3.77Ellagic acid ameliorates isoproterenol induced oxidative stress: Evidence from electrocardiological, biochemical and histological study. ( Kannan, MM; Quine, SD, 2011)
"The cardioprotective potential of Inula racemosa root hydroalcoholic extract against isoproterenol-induced myocardial infarction was investigated in rats."3.77Effect of Inula racemosa root extract on cardiac function and oxidative stress against isoproterenol-induced myocardial infarction. ( Arya, DS; Bharti, S; Bhatia, J; Kumari, S; Ojha, S; Rani, N; Sharma, AK, 2011)
"Four groups of experimental rats were subcutaneously injected with sesamol (0, 1, 3, or 10 mg/kg) and then, 2 h later, intraperitoneally injected with isoproterenol (100 mg/kg 24 h apart on 2 consecutive days) to induce myocardial infarction."3.77Sesamol attenuates isoproterenol-induced acute myocardial infarction via inhibition of matrix metalloproteinase-2 and -9 expression in rats. ( Chang, CC; Chen, SY; Liu, MY; Mo, FE; Periasamy, S, 2011)
"We investigated the antioxidant preventive effect of betaine on isoprenaline-induced myocardial infarction in male albino rats."3.76Antioxidant defense of betaine against isoprenaline-induced myocardial infarction in rats. ( Anandan, R; AnbinEzhilan, R; Buddhan, S; Ganesan, B; Sivakumar, R, 2010)
"The present work explores suspicious consequence of low molecular weight glycosaminoglycan (LMW-GAG) on oxidative stress and cellular abnormalities in isoproterenol (ISO)-induced myocardial infarction in an experimental model."3.76Preventive effect of low molecular weight glycosaminoglycan from Amussium pleuronectus (Linne) on oxidative injury and cellular abnormalities in isoproterenol-induced cardiotoxicity in Wistar rats. ( Saravanan, R; Shanmugam, A, 2010)
"It is known that various preparations of garlic and angiotensin-converting enzyme (ACE) inhibitor such as captopril (CAP) have beneficial effects on the left ventricular function and cardiovascular events after myocardial infarction (MI) when used individually."3.76Pharmacodynamic interaction of captopril with garlic in isoproterenol-induced myocardial damage in rat. ( Asdaq, SM; Inamdar, MN, 2010)
" After the pretreatment period, isoproterenol (100mg/kg) was injected to rats at an interval of 24h for two days to induce myocardial infarction."3.76Pretreatment with a combination of quercetin and alpha-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats. ( Prince, PS; Punithavathi, VR, 2010)
"The present study evaluated the protective effect of fish oil in isoproterenol-induced myocardial infarction in rats."3.76Protective effect of fish oil on changes in the activities of membrane-bound ATPases and mineral status in experimentally induced myocardial infarction in Wistar rats. ( Devi, CS; Kalaiselvi, P; Padma, VV, 2010)
" The aim of this study was to investigate the effect of selenium on NFκB activation in rats induced with myocardial infarction by isoproterenol (ISP)."3.76Impact of selenium on NFκB translocation in isoproterenol-induced myocardial infarction in rats. ( John, F; Madambath, I; Panicker, S; Swathy, SS, 2010)
"This study was designed to investigate the cardioprotective effect of sesamol on isoproterenol (ISO)-induced myocardial infarction in adult male albino Wistar rats."3.76Protective effect of sesamol against myocardial infarction caused by isoproterenol in Wistar rats. ( Pugalendi, KV; Vennila, L, 2010)
") juice (PJ) on heart weight, infarct size, plasma marker enzymes of cardiac damage, lipid peroxidation, endogenous enzymatic and non-enzymatic antioxidants, cardiac ATPases and histopathology of isoproterenol (IP)-induced cardiac necrosis (CN) in rats."3.76Pomegranate (Punica granatum L.) juice supplementation attenuates isoproterenol-induced cardiac necrosis in rats. ( Devkar, RV; Jadeja, RN; Patel, DK; Ramachandran, AV; Thounaojam, MC, 2010)
"The present study was designed to investigate the cardioprotective effect of melatonin against isoproterenol induced myocardial infarction in rats by studying myocyte injury markers, antioxidant defense system, serum and heart lipid profile, inflammatory markers, electrocardiographic and histopathological changes."3.76Cardioprotective effect of melatonin against isoproterenol induced myocardial infarction in rats: A biochemical, electrocardiographic and histoarchitectural evaluation. ( Balaraman, R; Patel, V; Upaganlawar, A; Zalawadia, R, 2010)
" Acute cardiogenic pulmonary edema was induced in C57BL/6J male mice by an increase in heart rate with continuous intravenous infusion of isoproterenol (ISP) (10 mg/kg/h) at 2 weeks after the creation of myocardial infarction by left coronary artery ligation."3.76Inhibition of secretory phospholipase A2 activity attenuates acute cardiogenic pulmonary edema induced by isoproterenol infusion in mice after myocardial infarction. ( Fujioka, D; Kawabata, K; Kobayashi, T; Kugiyama, K; Mishina, H; Nakamura, T; Obata, JE; Saito, Y; Watanabe, K; Watanabe, Y; Yano, T, 2010)
" In this study, cardioprotective activity of fucoidan extracted from Cladosiphon okamuranus was evaluated in isoproterenol induced myocardial infarction in rats."3.76Cardioprotective activity of Cladosiphon okamuranus fucoidan against isoproterenol induced myocardial infarction in rats. ( Pasanban, B; Rajendran, M; Rengasamy, R; Thomes, P, 2010)
" The purpose of the present study was to investigate the effects of CAPE on isoproterenol (ISO) -induced myocardial infarction."3.76Effects of caffeic acid phenethyl ester on isoproterenol-induced myocardial infarction in rats. ( Alçin, E; Aydin, M; Ilhan, S; Nacar, A; Oktar, S; Yönden, Z, 2010)
"The present study was undertaken to evaluate the preventive role of naringin on mitochondrial lipid peroxides, antioxidants and lipids in isoproterenol (ISO)-induced myocardial infarction (MI) in male Wistar rats."3.75Naringin ameliorates mitochondrial lipid peroxides, antioxidants and lipids in isoproterenol-induced myocardial infarction in Wistar rats. ( Prince, PS; Rajadurai, M, 2009)
"The present study was aimed to investigate the combined effects of green tea and vitamin E on heart weight, body weight, serum marker enzymes, lipid peroxidation, endogenous antioxidants and membrane bound ATPases in isoproterenol (ISO)-induced myocardial infarction in rats."3.75Effect of green tea and vitamin E combination in isoproterenol induced myocardial infarction in rats. ( Balaraman, R; Gandhi, C; Upaganlawar, A, 2009)
" This study was designed to evaluate the protective effect of gallic acid on cardiac marker enzymes, troponin-T, LDH-isoenzyme pattern, lipid peroxidation products and antioxidant status in isoproterenol (ISO)-induced myocardial infarction in male Wistar rats."3.75Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats. ( Prince, PS; Priscilla, DH, 2009)
"The present study evaluated cardioprotective effect of lyophilized hydroalcoholic extract of Moringa oleifera in the isoproterenol (ISP)-induced model of myocardial infarction."3.75Moringa oleifera leaf extract prevents isoproterenol-induced myocardial damage in rats: evidence for an antioxidant, antiperoxidative, and cardioprotective intervention. ( Arya, DS; Joshi, S; Kumari, S; Nandave, M; Ojha, SK, 2009)
"The study aimed to evaluate the protective role of myricetin obtained from Vitis vinifera (Vitaceae) on heart rate, electrocardiographic (ECG) patterns, vascular reactivity to catecholamines, cardiac marker enzymes, antioxidant enzymes together with morphological and histopathological changes in isoproterenol (ISO) induced myocardial infarction (MI) in male Wistar rats."3.75Cardioprotective potential of myricetin in isoproterenol-induced myocardial infarction in Wistar rats. ( Ballero, M; Kasture, S; Maxia, A; Mohan, M; Tiwari, R, 2009)
" calabura), a medicinal herb, on isoproterenol-induced myocardial infarction (MI) in rat models."3.75Effects of Muntingia calabura L. on isoproterenol-induced myocardial infarction. ( Brindha, P; Jayasri, J; Nivethetha, M, 2009)
" In the present study, we investigated the protective effect of betaine, a potent lipotropic molecule, on changes in the levels of membrane-bound ATPase activities, lipid peroxidation, sulfhydryl activities, and mineral status in isoprenaline-induced myocardial infarction in Wistar rats, an animal model of myocardial infarction in man."3.75Protective effect of betaine on changes in the levels of membrane-bound ATPase activity and mineral status in experimentally induced myocardial infarction in Wistar rats. ( Anandan, R; Buddhan, S; Ganesan, B; Jeyakumar, R, 2009)
"The present study was designed to evaluate the cardioprotective potential of salvianolic acid A on isoproterenol-induced myocardial infarction in rats."3.75Cardioprotective effect of salvianolic acid A on isoproterenol-induced myocardial infarction in rats. ( Du, GH; Tian, S; Wang, SB; Yang, F; Yang, HG; Yang, XY, 2009)
"The goal of this study was to investigate whether sub-chronic anti-oxidant treatment with ascorbic acid (Vit C) is able to protect the heart against myocardial infarction."3.75Ascorbic acid prevents acute myocardial infarction induced by isoproterenol in rats: role of inducible nitric oxide synthase production. ( Bergamaschi, CT; Buttros, JB; Campos, RR; Oshima, CT; Ribeiro, DA, 2009)
" At the end of treatment period, MI was induced by administering isoproterenol (ISO) or by subjecting heart to ischemia reperfusion injury (IRI)."3.75Role of Sida cordifolia L. leaves on biochemical and antioxidant profile during myocardial injury. ( Asdaq, SM; Kubavat, JB, 2009)
"An ultra-performance liquid chromatography/time-of-flight mass spectrometry (UPLC/TOF-MS)-based metabolomic approach was developed to characterize the metabolic profile associated with isoproterenol (ISO)-induced myocardial infarction (MI)."3.75Metabolomic profiling of rat serum associated with isoproterenol-induced myocardial infarction using ultra-performance liquid chromatography/time-of-flight mass spectrometry and multivariate analysis. ( Chen, X; Hu, P; Liang, QL; Liang, XP; Luo, GA; Wang, YM; Zhang, HY, 2009)
"We demonstrated that propranolol reduced the incidence of arrhythmias in a rat model of myocardial infarction by coronary artery occlusion."3.75MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection. ( Dong, D; Li, B; Li, X; Lu, Y; Pan, Z; Qiao, G; Shan, H; Song, W; Xu, C; Yang, B; Zhang, B; Zhang, F; Zhang, Y, 2009)
"This study investigates the cardioprotective activity of a combined treatment of Ginkgo biloba phytosomes (GBP) and Ocimum sanctum extract (Os) in isoproterenol (ISO)-induced myocardial necrosis in rats."3.75Evaluation of cardioprotective activity of Ginkgo biloba and Ocimum sanctum in rodents. ( N, SR; Panda, VS, 2009)
"This study was aimed to evaluate the combined effects of quercetin and alpha-tocopherol on lipid metabolism and glycoprotein components in isoproterenol induced myocardial infarction in Wistar rats."3.75Combined effects of quercetin and alpha-tocopherol on lipids and glycoprotein components in isoproterenol induced myocardial infarcted Wistar rats. ( Prince, PS; Punithavathi, VR, 2009)
" The present study has been designed to investigate whether telmisartan treatment attenuates the development of acute myocardial infarction in isoproterenol-treated rats by restoring hemodynamic, biochemical, histopathological and ultrastructural changes."3.75Myocardial salvaging effect of telmisartan in experimental model of myocardial infarction. ( Arora, S; Arya, DS; Goyal, S; Joshi, S; Kumari, S; Mittal, R; Nag, TC; Ray, R, 2009)
" We investigated the effects of cinaciguat on myocardial infarction induced by isoproterenol in rats."3.75Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury. ( Barnucz, E; Hirschberg, K; Karck, M; Korkmaz, S; Loganathan, S; Neugebauer, P; Páli, S; Radovits, T; Seidel, B; Szabó, G; Veres, G; Zöllner, S, 2009)
" The possible pharmacodynamic interaction between CCBs (verapamil, amlodipine and diltiazem) and BQ/BQT was studied on isoproterenol (ISO)-induced myocardial necrosis in mice."3.75Influence of betel quid on effect of calcium channel blockers on isoprenaline induced myocardial necrosis in mice. ( Asad, M; Asdaq, SM; Kumar, V, 2009)
"The present study was undertaken to evaluate the protective effect of (-)epigallocatechin gallate (EGCG) on mitochondrial lipids, lipid peroxides, Na(+)/K(+) ATPase, calcium and adenosine triphosphate in isoproterenol (ISO) induced myocardial infarction in male Wistar rats."3.74(-)Epigallocatechingallate protects the mitochondria against the deleterious effects of lipids, calcium and adenosine triphosphate in isoproterenol induced myocardial infarcted male Wistar rats. ( Devika, PT; Stanely Mainzen Prince, P, 2008)
"In the present study, cardioprotective effect of aqueous extract of fruits of Embelia ribes Burm (ER) was evaluated in a rat model having acute myocardial infarction, induced by isoproterenol (5."3.74Cardioprotective effect of aqueous extract of Embelia ribes Burm fruits against isoproterenol-induced myocardial infarction in albino rats. ( Ansari, MN; Bhandari, U; Islam, F, 2008)
"This study was aimed to evaluate the preventive role of S-allylcysteine (SAC) on creatine kinase-MB, iron, iron binding capacity, uric acid, total protein, membrane-bound enzymes such as sodium potassium-dependent adenosine triphosphatase, calcium-dependent adenosine triphosphatase and magnesium-dependent adenosine triphosphatase, and glycoproteins such as hexose, hexosamine, fucose and sialic acid in isoproterenol-induced myocardial infarction in rats."3.74Preventive effect of S-allylcysteine on membrane-bound enzymes and glycoproteins in normal and isoproterenol-induced cardiac toxicity in male Wistar rats. ( Padmanabhan, M; Prince, PS; Rajadurai, M, 2008)
" This study was aimed to evaluate the preventive role of naringin on cardiac troponin T (cTnT), lactate dehydrogenase (LDH)-isoenzyme, cardiac marker enzymes, electrocardiographic (ECG)-patterns and lysosomal enzymes in isoproterenol (ISO)-induced myocardial infarction (MI) in male Wistar rats."3.74Preventive effect of naringin on cardiac markers, electrocardiographic patterns and lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats. ( Rajadurai, M; Stanely Mainzen Prince, P, 2007)
"The protective effect of PUFA concentrate prepared from fish oil on isoproterenol-induced myocardial infarction in male albino rats was investigated with respect to changes in the levels of diagnostic marker enzymes, cholesterol, triglycerides, free fatty acids, phospholipids, reduced glutathione (GSH) and lipid peroxides (LPO)."3.74Protective effect of n-3 polyunsaturated fatty acids concentrate on isoproterenol-induced myocardial infarction in rats. ( Anandan, R; Mathew, S; Sankar, TV; Viswanathan Nair, PG, 2007)
"This study was aimed to evaluate the preventive role of naringin on heart weight, blood glucose, total proteins, albumin/globulin (A/G) ratio, serum uric acid, serum iron, plasma iron binding capacity and membrane bound enzymes such as sodium potassium-dependent adenosine triphosphatase (Na(+)/K(+) ATPase), calcium-dependent adenosine triphosphatase (Ca(2+) ATPase) and magnesium-dependent adenosine triphosphatase (Mg(2+) ATPase) and glycoproteins such as hexose, hexosamine, fucose and sialic acid in isoproterenol (ISO)-induced myocardial infarction (MI) in rats and in vitro free radical scavenging assay."3.74Preventive effect of naringin on isoproterenol-induced cardiotoxicity in Wistar rats: an in vivo and in vitro study. ( Prince, PS; Rajadurai, M, 2007)
"The present study was designed to evaluate the preventive role of rutin on lipids, lipoproteins, and ATPases in normal and isoproterenol (ISO)-induced myocardial infarction in rats."3.74Preventive effect of rutin on lipids, lipoproteins, and ATPases in normal and isoproterenol-induced myocardial infarction in rats. ( Karthick, M; Stanely Mainzen Prince, P, 2007)
"In our investigation,we used short-time model of myocardial infarction of rats induced by high dose of isoproterenol (ISP)."3.74Troponin T and histological characteristics of rat myocardial infarction induced by isoproterenol. ( Hasić, S; Jadrić, R; Kiseljaković, E; Mornjaković, Z; Winterhalter-Jadrić, M, 2007)
"Increased oxidative stress and antioxidant deficit have been suggested to play a major role in isoproterenol-induced myocardial infarction."3.74Cardioprotective effect of alpha-mangostin, a xanthone derivative from mangosteen on tissue defense system against isoproterenol-induced myocardial infarction in rats. ( Devi Sampath, P; Vijayaraghavan, K, 2007)
" The present study is undertaken to evaluate the preventive role of naringin on mitochondrial enzymes in isoproterenol (ISO)-induced myocardial infarction in male albino Wistar rats."3.74Preventive effect of naringin on cardiac mitochondrial enzymes during isoproterenol-induced myocardial infarction in rats: a transmission electron microscopic study. ( Prince, PS; Rajadurai, M, 2007)
"The present study was designed to investigate whether fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, would attenuate the acute myocardial infarction in isoproterenol-treated rat model via maintaining activities of endogenous antioxidant enzymes."3.74Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat. ( Dai, G; Xu, Q; Yan, L; Zheng, J; Zheng, P; Zhou, R, 2008)
" The aim of the present study was to evaluate the role of aldosterone and angiotensin II on formation of left ventricular fibrosis induced by chronic beta-adrenergic stimulation with isoproterenol (iso) in the rat heart failure model induced by myocardial infarction (MI)."3.73Inhibition of catecholamine-induced cardiac fibrosis by an aldosterone antagonist. ( Bos, R; Findji, L; Lechat, P; Médiani, O; Mougenot, N; Vanhoutte, PM, 2005)
"We demonstrate the effect of Aegle marmelos leaf extract (AMLEt) and alpha-tocopherol on plasma lipids, lipid peroxides and marker enzymes in rats with isoproterenol (ISO)-induced myocardial infarction."3.73Comparative effects of Aegle marmelos extract and alpha-tocopherol on serum lipids, lipid peroxides and cardiac enzyme levels in rats with isoproterenol-induced myocardial infarction. ( Prince, PS; Rajadurai, M, 2005)
" Prior to 20 min of global ischemia, mouse hearts were either perfused for 30 min without treatment (control), treated with 10 nmol/L of isoproterenol (ISO) for 5 min followed by 5 min washout, or preconditioned with 4 cycles of 5 min ischemia and 5 min reflow (PC)."3.73The role of beta-adrenergic receptor signaling in cardioprotection. ( Bernstein, D; Murphy, E; Steenbergen, C; Tong, H, 2005)
" The protective effect of DHC-1 in isoproterenol-induced myocardial infarction and cisplatin-induced renal damage were studied."3.73Antioxidant activity of DHC-1, an herbal formulation, in experimentally-induced cardiac and renal damage. ( Bafna, PA; Balaraman, R, 2005)
"Isolated perfused hearts from young (3-5 months) and aging (24-25 months) rats were subjected to 60 min of 50% coronary flow reduction and 30 min of isoproterenol (Iso) stimulation starting at 30 min of ischemia."3.73Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury. ( Gao, F; Grunwald, Z; Hu, A; Li, D; Liu, H; Ma, XL; Qu, Y; Sharifi-Azad, S; Sun, JZ; Tao, L, 2006)
"We have examined the protective effect of taurine on the myocardial antioxidant defense system in isoprenaline (isoproterenol)-induced myocardial infarction in rats, an animal model of myocardial infarction in man."3.73Protective effect of taurine on myocardial antioxidant status in isoprenaline-induced myocardial infarction in rats. ( Anandan, R; Devadasan, K; Farvin, KH; Kumar, SH; Shiny, KS, 2005)
"We have evaluated the preventive effects of an aqueous Aegle marmelos leaf extract (AMLEt) in isoprenaline (isoproterenol)-induced myocardial infarction in rats."3.73Preventive effect of Aegle marmelos leaf extract on isoprenaline-induced myocardial infarction in rats: biochemical evidence. ( Prince, PS; Rajadurai, M, 2005)
"Isoproterenol (ISPH) induced myocardial infarction was confirmed by disturbances in serum and heart tissue marker enzymes such as lactate dehydrogenase (LDH), creatine phospho kinase (CPK), aspartate transaminase (AST) and alanine transaminase (ALT), increased level of lipid peroxidation and histopathological changes in the heart of ISPH administered rats."3.73Cardioprotective effect of mangiferin on isoproterenol induced myocardial infarction in rats. ( Devi, CS; Jainu, M; Prabhu, S; Sabitha, KE, 2006)
"These results indicate that (1) Both IPC and beta-PC elicit protection against apoptosis and necrosis, (2) activation of p38 MAPK is not a trigger of preconditioning against apoptosis and necrosis and (3) activation of p38 MAPK during reperfusion increases necrosis only if ischaemia is used to precondition hearts, but not with pharmacologic preconditioning with isoproterenol."3.73Inhibition of myocardial apoptosis by ischaemic and beta-adrenergic preconditioning is dependent on p38 MAPK. ( Hartley, S; Lochner, A; Marais, E; Moolman, JA; Van Wyk, J, 2006)
"In the present study, chronic treatment of atorvastatin was evaluated on isoproterenol-induced myocardial infarction."3.73Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats. ( Balaraman, R; Bothara, SB; Majithiya, JB; Trivedi, CJ, 2006)
" (Anacardiaceae), on isoproterenol (ISPH)-induced myocardial infarction (MI) in rats through its antioxidative mechanism."3.73Role of mangiferin on biochemical alterations and antioxidant status in isoproterenol-induced myocardial infarction in rats. ( Devi, CS; Jainu, M; Prabhu, S; Sabitha, KE, 2006)
"The effect of fish oil treatment on the activities of antioxidants such as superoxide dismutase, catalase, glutathione peroxidase, glutathione-s-transferase, and glutathione, as well as the level of the lipid peroxidation marker thiobarbituric reactive substance was studied in isoproterenol-induced myocardial infarction (MI)."3.73Modulatory effect of fish oil on the myocardial antioxidant defense system in isoproterenol-induced myocardial infarction. ( Devi, CS; Padma, VV; Ramkumar, KM, 2006)
" This study aimed to evaluate the preventive role of rutin on lipid peroxides and antioxidants in normal and isoproterenol-induced myocardial infarction in rats."3.73Preventive effect of rutin, a bioflavonoid, on lipid peroxides and antioxidants in isoproterenol-induced myocardial infarction in rats. ( Karthick, M; Stanely Mainzen Prince, P, 2006)
" A novel PARP inhibitor (L-2286) was tested in a rat model of chronic heart failure following isoproterenol-induced myocardial infarction."3.73PARP inhibition prevents postinfarction myocardial remodeling and heart failure via the protein kinase C/glycogen synthase kinase-3beta pathway. ( Deres, P; Gallyas, F; Halmosi, R; Hanto, K; Hideg, K; Kalai, T; Kulcsar, G; Palfi, A; Sumegi, B; Szabados, E; Szereday, Z; Toth, A; Toth, K, 2006)
"Inhibition of the multifunctional Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) or depletion of sarcoplasmic reticulum (SR) Ca(2+) stores protects against apoptosis from excessive isoproterenol (Iso) stimulation in cultured ventricular myocytes, suggesting that CaMKII inhibition could be a novel approach to reducing cell death in conditions of increased adrenergic tone, such as myocardial infarction (MI), in vivo."3.73Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo. ( Anderson, ME; Eren, M; Gleaves, L; Hou, Y; Joiner, ML; Ni, G; Oddis, CV; Price, EE; Vaughan, DE; Xiao, RP; Yang, J; Yang, Y; Zhang, R; Zhu, WZ, 2006)
"Our study evaluates the preventive effect of S-allyl cysteine sulfoxide (SACS) on lipid peroxidative products and enzymic and nonenzymic antioxidants in isoproterenol (ISO) induced myocardial infarction in rats."3.73Antilipoperoxidative and antioxidant effects of S-allyl cysteine sulfoxide on isoproterenol-induced myocardial infarction in Wistar rats. ( Quine, SD; Sangeetha, T, 2006)
"This study was designed to evaluate the preventive effect of naringin in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."3.73Preventive effect of naringin on lipids, lipoproteins and lipid metabolic enzymes in isoproterenol-induced myocardial infarction in Wistar rats. ( Rajadurai, M; Stanely Mainzen Prince, P, 2006)
" The cardiotoxicity was induced by myocardial infarction through subcutaneous administration of isoproterenol hydrochloride for 2 days using 0."3.73Efficacy of mangiferin on serum and heart tissue lipids in rats subjected to isoproterenol induced cardiotoxicity. ( Nair, PS; Shyamala Devi, CS, 2006)
"This study was designed to evaluate the cardioprotective potential of naringin on lipid peroxides, enzymatic and nonenzymatic antioxidants and histopathological findings in isoproterenol (ISO)-induced myocardial infarction (MI) in rats."3.73Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: biochemical and histopathological evidences. ( Rajadurai, M; Stanely Mainzen Prince, P, 2006)
"Pepticare, a herbomineral formulation, was administered orally to rats at the dose levels of 125, 250, 500 and 1000 mg/kg to investigate its effect on isoproterenol-induced myocardial infarction and cisplatin-induced renal damage."3.73Antioxidant activity of Pepticare, a herbomineral formulation, in experimentally induced renal and cardiac damage. ( Bafna, PA; Balaraman, R, 2006)
"We studied the cardioprotective effect of squalene on isoprenaline-induced myocardial infarction in male albino rats with respect to changes in the levels of lipid components in plasma and heart tissue."3.73Cardioprotective effect of squalene on lipid profile in isoprenaline-induced myocardial infarction in rats. ( Anandan, R; Farvin, KH; Kumar, SH; Mathew, S; Nair, PG; Sankar, TV; Shiny, KS, 2006)
"Administration of isoproterenol to mice at a dose of 30 mg/100 g body weight for 3 consecutive days at an interval of 24 h induced lipid peroxidation in cardiac tissue and exhibited a significantly elevated serum glutamate oxaloacetate transaminase (SGOT) level."3.72Effect of isoproterenol on lipid peroxidation and antioxidant enzymes of myocardial tissue of mice and protection by quinidine. ( Bandyopadhyay, D; Biswas, S; Chattopadhyay, A; Datta, AG; Sarkar, C, 2003)
" Cardiac lesions induced by isoproterenol (ISO) are characterized by myocardial necrosis and exudative infiltration."3.72Effect of D-003 on isoproterenol-induced myocardial necrosis in rats. ( Arruzazabala, ML; Carbajal, D; González, J; Más, R; Mendoza, S; Molina, V; Noa, M, 2003)
"The protective effect of L-arginine and L-lysine on lysosomal enzymes and membrane bound ATPases was examined on isoproterenol induced myocardial infarction in rats."3.72Effect of L-arginine and L-lysine on lysosomal hydrolases and membrane bound phosphatases in experimentally induced myocardial infarction in rats. ( Devaki, T; Ebenezar, KK; Sathish, V, 2003)
"The synergistic protective effect of nicorandil (KATP channel opener) and amlodipine (calcium channel blocker) on mitochondrial respiration and mitochondrial lipid contents were examined on isoproterenol-induced myocardial infarction in rats."3.72Biochemical changes on the cardioprotective effect of nicorandil and amlodipine during experimental myocardial infarction in rats. ( Devaki, T; Ebenezar, KK; Sathish, V, 2003)
"Animals with heart failure exhibited depressions in ventricular function, positive inotropic response to isoproterenol, beta-AR receptor density and basal AC activity; these changes were also attenuated by PLC treatment."3.72Improvement of cardiac function and beta-adrenergic signal transduction by propionyl L-carnitine in congestive heart failure due to myocardial infarction. ( Dhalla, NS; Ferrari, R; Sethi, R; Wang, X, 2004)
"This study was designed to examine the effects of squalene on tissue antioxidant status in isoproterenol-induced myocardial infarction in male albino rats."3.72Effect of squalene on tissue defense system in isoproterenol-induced myocardial infarction in rats. ( Anandan, R; Kumar, SH; Sabeena Farvin, KH; Sankar, TV; Shiny, KS; Thankappan, TK, 2004)
"Myocardial infarction was produced by subcutaneous administration of isoproterenol hydrochloride (85 mg/kg b."3.72Comparative account of certain enzymes in the serum of homo-iothermal vertebrates subjected to production of myocardial infarction by isoproterenol hydrochloride. ( Gaur, M; Kumar, S, 2003)
"The present study was conducted to elucidate the antioxidant role of garlic oil in isoproterenol (IPL)-induced myocardial infarction in rats."3.72Effect of garlic (Allium sativum) on lipid peroxidation in experimental myocardial infarction in rats. ( Prakash, J; Saravanan, G, 2004)
"Antioxidant role of Arogh in isoproterenol induced myocardial infarction in rats has been studied."3.72Role of Arogh, a polyherbal formulation to mitigate oxidative stress in experimental myocardial infarction. ( Maheswaran, E; Shyamala Devi, CS; Suchalatha, S; Thirugnanasambandam, P, 2004)
" In a randomized prospective trial design, we administered the XO inhibitor allopurinol orally to mice that had undergone massive myocardial infarction (MI)."3.72Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy. ( Gao, WD; Leppo, MK; Marbán, E; Stull, LB; Szweda, L, 2004)
" The aim of the present study is to study the effect of folic acid and Vitamin B(12) supplementation on isoprenaline (ISO)-induced myocardial infarction (MI) in hyperhomocysteinemic rats."3.71Folic acid and vitamin B(12) supplementation attenuates isoprenaline-induced myocardial infarction in experimental hyperhomocysteinemic rats. ( Hagar, HH, 2002)
"ET, CGRP or NO is involved in myocardial infarction caused by isoproterenol."3.71[Variation of endogeneous ET, CGRP and NO in myocardial ischemia in rats and the regulatory effect of xinshuping]. ( Chen, SZ; Li, CL; Liu, XY; Wang, YY, 2002)
"The cardioprotective effect of the ethanol extract of Picrorrhiza kurroa rhizomes and roots (PK) on isoproterenol-induced myocardial infarction in rats with respect to lipid metabolism in serum and heart tissue has been investigated."3.71Cardioprotective effects of Picrorrhiza kurroa against isoproterenol-induced myocardial stress in rats. ( Anandan, R; Devaki, T; Santhosh Kumar, M; Senthil Kumar, SH, 2001)
"Myocardial infarction (MI) was produced in rats with 85, 200 and 300 mg/kg of isoproterenol (ISO) administered subcutaneously (sc) twice at an interval of 24 h."3.71Cardioprotective potential of ocimum sanctum in isoproterenol induced myocardial infarction in rats. ( Arya, DS; Gupta, SK; Joshi, S; Kishore, K; Sharma, M, 2001)
"The effects of SMP-300, an orally active, potent, and selective Na+/H+ exchange inhibitor, were evaluated and compared with those of nifedipine, propranolol, and nicorandil on three experimental angina models and on myocardial infarction in rats."3.71Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats. ( Matsui, K; Ohashi, N; Sasabe, M; Yamamoto, S, 2002)
"The synergistic effects of nicorandil (KATP-channel opener) and amlodipine (calcium-channel blocker) on heart mitochondrial enzymes and the mitochondrial antioxidant defence system was examined on isoproterenol-induced myocardial infarction in rats."3.71Synergistic effect of nicorandil and amlodipine on mitochondrial function during isoproterenol-induced myocardial infarction in rats. ( Devaki, T; Ebenezar, KK; Sathish, V; Vimal, V, 2002)
"The equivalent of the clinically used low (= antiplatelet)-dose aspirin, inhibited collagen deposition in the non-infarcted myocardium in rats with myocardial infarction."3.70Low-dose aspirin improves in vivo hemodynamics in conscious, chronically infarcted rats. ( Kalkman, EA; Saxena, PR; Schoemaker, RG, 1998)
"The effect of alpha-tocopherol pretreatment (6 mg/100 g body wt/day, orally for a period of 90 days) on mitochondrial electron transport in myocardial infarction induced by isoproterenol (20 mg/100 g body wt, subcutaneously for two days) was studied in rats."3.70Effect of alpha-tocopherol on mitochondrial electron transport in experimental myocardial infarction in rats. ( Ithayarasi, AP; Shyamala Devi, C, 1998)
" in isoproterenol-induced myocardial infarction and CCl4-induced hepatotoxicity in rats."3.70Antioxidant activity of AO-8, a herbal formulation in vitro and in vivo experimental models. ( Gopumadhavan, S; Mitra, SK; Sundaram, R; Venkataranganna, MV, 1999)
" Male Wistar rats with ligation-induced myocardial infarction were assigned to placebo or treatment with mibefradil (10 mg/kg/day), verapamil (8 mg/kg/day), or amlodipine (4 mg/kg/day) by oral gavage starting 7 days before the induction of myocardial infarction."3.70Differential effects of mibefradil, verapamil, and amlodipine on myocardial function and intracellular Ca(2+) handling in rats with chronic myocardial infarction. ( Meissner, A; Min, JY; Sandmann, S; Simon, R; Unger, T, 1999)
"We administered oral metoprolol or no therapy to rats for 12 weeks after large myocardial infarction and subsequently examined left ventricular (LV) remodeling; myocardial tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6 expression; and NO."3.70beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling. ( Chandrasekar, B; Freeman, GL; Murray, DR; Prabhu, SD, 2000)
" To examine the status of beta-adrenergic receptors and postadrenergic receptor mechanisms in congestive heart failure due to myocardial infarction, the left coronary artery in rats was ligated for 4 and 8 weeks before studying the hemodynamic and biochemical changes due to isoproterenol, a beta-adrenoceptor agonist, or forskolin, a postreceptor agonist."3.69Inotropic responses to isoproterenol in congestive heart failure subsequent to myocardial infarction in rats. ( Dhalla, NS; Sethi, R, 1995)
"The mechanism of exercise-induced ST-segment elevation in previous myocardial infarction was investigated using isoproterenol infusion with atrial pacing to simulate exercise hemodynamics in seven closed chest dogs with myocardial infarction."3.69[Isoproterenol induces ST-segment elevation without wall motion aggravation and myocardial ischemia in experimental myocardial infarction]. ( Katori, R; Yamamoto, T, 1995)
"Myocytes isolated from rat hearts that have suffered 35% myocardial infarction (MI) 3 wk prior have lower peak cytosolic Ca2+ concentration ([Ca2+]i) during contraction compared with Sham myocytes, a difference that is amplified by isoproterenol or high extracellular Ca2+ concentration ([Ca2+]o)."3.69Calcium currents in postinfarction rat cardiac myocytes. ( Cheung, JY; Moore, RL; Tillotson, DL; Zhang, XQ, 1995)
" We investigated the regulation of the atrial natriuretic peptide and brain natriuretic peptide genes in a rat model of myocardial infarction induced by isoproterenol (IP rat) and in a rat model of cardiac hypertrophy induced by aorto-caval shunt (AC shunt rat)."3.69Differential regulation of natriuretic peptide genes in infarcted rat hearts. ( Iwai, N; Kinoshita, M; Shimoike, H, 1997)
"The effect of alpha-tocopherol (6 mg/100 g body wt, orally, daily for 90 days) pretreatment in isoproterenol (20 mg/100 g body wt, subcutaneously, twice at an interval of two days at the end of the alpha-tocopherol pretreatment) induced myocardial infarction was studied in rats."3.69Effect of alpha-tocopherol on isoproterenol induced myocardial infarction in rats--electrocardiographic biochemical and histological evidences. ( Ithayarasi, AP; Padmavathy, VN; Shyamala Devi, C, 1996)
"The effect of alpha-tocopherol pretreatment on lipid peroxidation and antioxidant status in isoproterenol induced myocardial infarction was studied in rats."3.69Effect of alpha-tocopherol on lipid peroxidation in isoproterenol induced myocardial infarction in rats. ( Devi, CS; Ithayarasi, AP, 1997)
" Because adrenergic stimulation decreases serum K+ and Mg++, we decided to investigate the effects of a beta-receptor agonist, isoproterenol, on serum K+ and Mg++, and their consequences on the induction of tachycardia."3.68Effect of isoproterenol on serum potassium and magnesium. ( Beurrier, D; Brembilla-Perrot, B; le Van, D; Terrier de la Chaise, A, 1993)
"Myocardial infarction was induced in albino rats by the subcutaneous administration of isoproterenol."3.68Collagen levels in isoproterenol induced myocardial infarction in rats. ( Puvanakrishnan, R; Ravichandran, LV, 1993)
"The amounts of myocardial metallothionein (MT) and heavy metal (Zn, Cu) levels during the early stage of the experimental myocardial infarction model induced by isoproterenol (Isp) administration were measured by an atomic absorption spectrophotometry."3.68[Changes in myocardial metallothionein on isoproterenol-induced myocardial injury]. ( Akai, F; Hashimoto, S; Kimoto, S; Namikawa, K; Nishida, S; Okazaki, Y; Tomura, T, 1993)
"In this study the effect of the angiotensin converting enzyme (ACE) inhibitor captopril on beta-receptor responsiveness was investigated in failing rat hearts after experimental myocardial infarction."3.68Captopril modifies the response of infarcted rat hearts to isoprenaline stimulation. ( Bartels, H; de Graeff, PA; de Langen, CD; Monnink, SH; van Gilst, WH; van Wijngaarden, J; Wesseling, H, 1992)
"2 mg/100 g body wt orally for 30 days) on myocardial infarction induced by isoproterenol (200 mg/kg body wt, subcutaneously for 2 days) has been studied in rats using activities of creatine kinase, aspartate amino transaminase, alanine amino transaminase and lactate dehydrogenase and levels of lipid peroxides as standard markers."3.68Effect of aspirin on isoproterenol induced myocardial infarction--a pilot study. ( Devi, CS; Geetha, A; Manjula, TS, 1992)
"The amount of peroxide lipid in vivo in the early stage of the experimental model of myocardial infarction in a rat induced by the administration of isoproterenol (Isp) was measured as the value of malonic dialdehyde (MDA)."3.68[Studies on early stage changes of peroxide lipid in isoproterenol-induced myocardial injury]. ( Hashimoto, S; Kadota, E; Namikawa, K; Nishida, S; Okazaki, Y; Tomura, T, 1992)
"The DNA synthesis has been studied in the conductive system (CS) myocytes, compared to that in atrial and ventricular myocytes: 1) in the left ventricular myocardial infarction induced in two- and three-week-old and adult rats, 2) after isoproterenol injections to adult rats and mice, and 3) in the hypertrophied human heart."3.68[The capacity for reactive DNA synthesis of the myocytes in the heart conduction system in experimental and clinical myocardial pathology]. ( Erokhina, IL, 1992)
"The prophylactic role of ibuprofen in experimental myocardial infarction has not been reported."3.68Failure to reduce experimental myocardial infarct size with ibuprofen pre-treatment in rats. ( Lal, A; Sharma, ML, 1992)
"Effects of acute myocardial infarction (48 h) on cardiovascular responses to (+/-)-, (-)-, and (+)-dobutamine were studied in isolated perfused rat hearts."3.68Cardiovascular responses to the stereoisomers of dobutamine in isolated rat hearts 48 hours after acute myocardial infarction. ( Porsius, AJ; van Rooij, HH; Vleeming, W; Wemer, J, 1991)
"The aim was to compare the effects of two novel angiotensin converting enzyme (ACE) inhibitors, spirapril and zofenopril, on cardiac remodelling in rats with congestive heart failure after myocardial infarction."3.68Converting enzyme inhibition after experimental myocardial infarction in rats: comparative study between spirapril and zofenopril. ( de Graeff, PA; de Langen, CD; Pinto, YM; van Gilst, WH; van Wijngaarden, J; Wesseling, H, 1991)
"Effect of ethanol administration on the severity of myocardial infarction induced by isoproterenol in rats was studied."3.68Effect of ethanol administration on metabolism of lipids in heart and aorta in isoproterenol induced myocardial infarction in rats. ( Kumari, S; Kurup, PA; Menon, PV; Remla, A, 1991)
"Effect of feeding safflower oil and coconut oil in experimental myocardial infarction induced by isoproterenol in rats was studied."3.68Effect of coconut oil & safflower oil on lipids in isoproterenol induced myocardial infarction in rats. ( Kurup, PA; Menon, PV; Remla, A, 1991)
", beta-glucuronidase, beta-N-acetylglucosaminidase, beta-galactosidase, beta-glucosidase, alpha-glucosidase, alpha-galactosidase, alpha-mannosidase, cathepsin B, cathepsin D, and collagenolytic cathepsin, in serum and heart of rats subject to myocardial infarction with isoproterenol, were studied during the periods of peak infarction and recovery."3.68Influence of isoproterenol-induced myocardial infarction on certain glycohydrolases and cathepsins in rats. ( Joseph, KT; Puvanakrishnan, R; Ravichandran, LV, 1991)
"The alterations in the heart lysosomal stability following isoproterenol induced myocardial infarction were studied in albino rats."3.68Alterations in the heart lysosomal stability in isoproterenol induced myocardial infarction in rats. ( Joseph, KT; Puvanakrishnan, R; Ravichandran, LV, 1990)
"The influence of isoproterenol on induction of ventricular arrhythmias was evaluated in 10 normal dogs and 17 dogs with experimentally induced myocardial infarction."3.68Effect of isoproterenol on induction of ventricular tachyarrhythmias in the normal and infarcted canine heart. ( Hunt, GB; Ross, DL, 1990)
"Beta-Adrenoceptor agonists, such as isoproterenol, produce ventricular fibrillation and myocardial necrosis in rats."3.67Ventricular fibrillation threshold and myocardial cyclic AMP production in rats sensitive or resistant to isoproterenol. ( Balazs, T; Jordan, AW; Joseph, X, 1984)
"The changes in plasma level of alpha-atrial natriuretic polypeptide (alpha-ANP) and the relaxing responses to exogenous alpha-ANP of strips of rat aorta pretreated with methoxamine were examined at one, four and eight weeks after myocardial infarction induced by left coronary ligation."3.67Changes in plasma level of alpha-atrial natriuretic polypeptide (alpha-ANP) and responsiveness of the aorta to exogenous alpha-ANP subsequent to myocardial infarction in rats. ( Hayashi, Y; Nakashima, M; Sato, R; Uematsu, T; Wang, YT, 1989)
"The susceptibility of the cardiovascular system to exposure to a high-boiling coal liquid (heavy distillate, HD) was studied in the rat using an isoproterenol (ISO) myocardial infarction model."3.67Elevated blood pressure and heart rate in rats exposed to a coal-derived complex organic mixture. ( Lundstrom, DL; Mahlum, DD; Sasser, LB; Springer, DL; Zangar, RC, 1989)
"The effect of vitamin E administration on the severity of myocardial infarction induced by isoproterenol on rats was studied."3.67Effect of vitamin E on the severity of myocardial infarction induced by isoproterenol. ( Kumari, SS; Menon, VP; Muraleedharan, D; Varghese, A, 1989)
" Radionuclide ventriculograms were obtained in 75 consecutive patients 2 weeks after myocardial infarction, at rest and during intravenous isoproterenol infusion."3.67The assessment of contractile reserve after thrombolytic therapy for acute myocardial infarction. ( Del Negro, AA; Fox, LM; Goldstein, HA; Green, CE; Kent, KM; Pallas, RS; Pearle, DL; Rackley, CE; Rogers, WJ; Satler, LF, 1986)
"Effect of UM-272, a dimethyl propranolol has been studied in experimental myocardial necrosis induced by isoproterenol (ISP, 85 mg/kg, SC X 2 days) in rats."3.67Alterations in isoproterenol-induced cardiac metabolic changes by a quaternary analog of propranolol, UM-272. ( Gupta, M; Gupta, MP; Manchanda, SC; Seth, SD; Srivastava, LM, 1985)
"The effects of the intravenous administration of hyaluronidase (HY; 2,500 IU/kg) and urokinase (UK; 20,000 and 40,000 IU/kg), alone or in combination, on the isoproterenol (ISP) induced myocardial infarction (MI) in rats, were studied."3.67The co-operative action of hyaluronidase and urokinase on the isoproterenol-induced myocardial infarction in rats. ( Antonetti, F; Borrelli, F; Caprino, L; Martelli, F, 1986)
"The effect of administration of carnitine on the severity of myocardial infarction in rats induced by isoproterenol was studied by following histopathological and biochemical parameters."3.67Effect of administration of carnitine on the severity of myocardial infarction induced by isoproterenol in rats. ( Kurup, PA; Mathew, S; Menon, PV, 1986)
" Seven days later, the animals were challenged with a dose of isoproterenol which would produce massive myocardial infarction and 50-60% mortality in non-treated animals."3.67Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats. ( Wexler, BC, 1985)
"The significance of the test with intravenous injection of isoproterenol in the diagnosis of coronary heart disease (CHD) was evaluated in comparison with the clinical, bicycle ergometry and selective coronarography data obtained in 65 women."3.67[Intravenous isoproterenol administration for diagnosing ischemic heart disease in women: a comparison with the data from bicycle ergometry and selective coronary angiography]. ( Akhmedzhanov, NM; Liakishev, AA; Matveeva, LS; Sidorenko, BA, 1985)
"Prophylactic effects of sulfinpyrazone (100 mg/Kg), aspirin (5 mg/Kg, 50 mg/Kg), and propranolol (2 mg/Kg, 10 mg/Kg) on myocardial necrosis and hypertrophy induced by isoproterenol were examined."3.66Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis. ( Hashimoto, H; Ogawa, K, 1981)
"Two different conditions responsible for cardiac hypertrophy in the rat were investigated: the first one is isoproterenol-induced myocardial infarct, the second is exposure to hypoxia (0."3.66Myocardial hypertrophy in the rat. Correlation between two experimental models. ( Cacciapuoti, AA; Chiariello, M; Condorelli, M; Ferro, G; Genovese, A, 1980)
"Male and female, normotensive, Sprague-Dawley (S-D) rats, and spontaneously hypertensive rats (SHR) were subjected to acute and massive myocardial infarction with isoproterenol."3.66Hormonal and metabolic changes during acute myocardial infarction in normotensive vs hypertensive rats. ( McMurtry, JP; Wexler, BC, 1983)
"The effect of exercise on the severity of isoproterenol-induced acute myocardial infarction was studied in male rats."3.66Beneficial effects of exercise on l-isoproterenol induced myocardial infarction in male rats. ( Darrah, MI; Engen, RL, 1982)
"To determine the relative effect of body weight and physical inactivity on susceptibility to drug-induced myocardial infarction, randomly selected groups of 100-day-old male Sprague-Dawley rats were subjected to a 10-wk program of exercise training and (or) to caloric restriction followed by two subcutaneous injections of L-isoproterenol."3.66Relative role of caloric restriction and exercise training upon susceptibility to isoproterenol-induced myocardial infarction in male rats. ( Beitz, DC; Crandall, DL; Feirer, RP; Griffith, DR, 1981)
" Some of the animals were treated with the anti-hyperuricemic agent, allopurinol, either before or during the induction of myocardial infarction."3.66Allopurinol amelioration of the pathophysiology of acute myocardial infarction in rats. ( McMurtry, JP; Wexler, BC, 1981)
"Tachycardia- and bradycardia-dependent, left anterior and left posterior hemiblocks as transient phenomena were registered in two patients spontaneously, and especially as a consequence of isoproterenol infusion."3.66Transient tachycardia- and bradycardia-dependent left anterior and left posterior hemiblocks. Effects of isoproterenol. ( Alvarez, JA; Kretz, A; Leguizamon Palumbo, JR; Martinez Martinez, JA; Suarez, LD, 1981)
"The effect of phenelzine on isoproterenol-induced myocardial necrosis was studied in rats."3.66Effect of phenelzine, a monoamine oxidase inhibitor, on isoproterenol-induced myocardial damage. ( Joshi, KC; Singh, KP; Somani, KC; Tariq, M, 1980)
"The effect of isoproterenol infusion on regional myocardial perfusion and tissue oxygenation during acute myocardial infarction was investigated in anesthetized dogs."3.66Effect of isoproterenol on regional myocardial perfusion and tissue oxygenation in acute myocardial infarction. ( Grover, FL; Horwitz, LD; Schwartz, DA, 1979)
"Adult male and female Sprague-Dawley rats were subjected to an isoproterenol-induced myocardial infarction."3.66Effect of gonadectomy on isoproterenol-induced myocardial infarction. ( Greenberg, BP; Wexler, BC, 1979)
" suggest that the myocardial infarction induced by isoproterenol in the rat may be determined by phenomenons of intracoronaric platelets aggregation."3.66[The role of the platelets in myocardial infarction induced by isoproterenol in the rat (author's transl)]. ( Cacciapuoti, AA; Genovese, A; Giuffrida, G; Mazza, F; Polverino, W, 1979)
"Changes in myocardial zinc level was followed up over a period of 5 days after producing myocardial necrosis in albino rats by subcutaneous injection of isoproterenol, 85 mg/kg body weight."3.66A temporal profile of myocardial zinc changes after isoproterenol induced cardiac necrosis. ( Ahmad, MS; Hasan, MZ; Jamil, SA; Kumar, S; Mathew, BM; Seth, TD, 1978)
"Male and female, arteriosclerotic and non-arteriosclerotic rats were treated with the anti-lipemic agent, clofibrate, for 8 days and then subjected to an acute myocardial infarction by injecting them with two large doses of isoproterenol spaced 24 hours apart."3.66Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats. ( Greenberg, BP; Wexler, BC, 1978)
" Hyaluronidase, insulin, potassium chloride, and isoproterenol increased myocardial tissue damage whereas heparin and prednisolone administration resulted in decreased myocardial tissue damage after induced myocardial infarction in rats."3.66Effects of pharmacological intervention on infarct size following induced myocardial infarction in rats. ( Barletta, MA; Lau Cam, C; Lynch, VD; Staab, R, 1978)
"The cardiovascular effects of halothane-nitrous oxide anesthesia, and beta-receptor blockade with either propranolol or practolol, were studied in 15 dogs in which severe myocardial infarction had been induced ten days earlier."3.65Interaction of anesthesia, beta-receptor blockade, and blood loss in dogs with induced myocardial infarction. ( Bennett, MJ; Clarke, TN; Foëx, P; Prys-Roberts, C; Roberts, JG; Ryder, WA, 1976)
"A brief characteristics of the main therapeutic methods for shock in acute myocardial infarction cases is presented, including fast infusion of plasma-substitutes, noradrenalin, isoproterenol, alpha-adrenergic bocking agents, steroid hormones, intra-aortal balloon counter-pulsation, oxygen therapy, acidbase balance correction, etc."3.65[Treatment of coronary shock]. ( Gratsianskiĭ, NA, 1975)
"The appearance of circulating anti-heart antibodies and myocardium-bound antibodies was demonstrated after experimental myocardial infarction induced by coronary ligation or high doses of isoproterenol in rats."3.65Immunofluorescent and migration inhibition studies in rats with experimental myocardial infarction. ( Csáky, L; Nosztray, K; Szabó, J; Szegi, J, 1976)
"The effect of exercise on the severity of isoproterenol-induced myocardial infarction was studied in male rats."3.65Effects of exercise on the severity of isoproterenol-induced myocardial infarction. ( Bonner, HW; Jessup, GT; Landiss, CW; Riggs, CE, 1977)
"Trapidil increases the isoprenalin-induced necrosis of the myocardium in the rat."3.65[Modification of the isoprenaline-induced myocardial necrosis using trapidil]. ( Lampe, D; Lange, B; Mai, I, 1976)
" The relative amounts of various polyunsaturated fatty acids in cardiac lipids influence markedly the development of myocardial necrosis and mortality following overstimulation with isoproterenol."3.65The role of myocardial membrane lipids in the development of cardiac necrosis. ( Gudbjarnason, S; Hallgrimsson, J, 1976)
"A 39-year-old women inhaled approximately 675 mg of aerosolized isoproterenol in less than three days during an asthmatic attack."3.65An electrocardiographic pattern of acute myocardial infarction associated with excessive use of aerosolized isoproterenol. ( Aelony, Y; Beall, G; Laks, MM, 1975)
"Mature male Sprague-Dawley rats were subjected to an isoproterenol-induced myocardial infarction."3.65Prolyl hydroxylase and collagen metabolism after experimental mycardial infarction. ( Judd, JT; Wexler, BC, 1975)
"Male and female, arteriosclerotic and nonarteriosclerotic rats were subjected to acute myocardial infarction by two, subcutaneous injections (spaced 24 hr apart) of isoproterenol."3.65Metabolic and histopathologic changes in arteriosclerotic versus nonarteriosclerotic rats following isoproterenol-induced myocardial infarction with superimposed diabetes. ( Wexler, BC, 1975)
" Therefore, the myocardial metabolism was studied at different environmental temperatures in albino rats with isoproterenol-induced infarct-like myocardial necrosis."3.65Myocardial metabolism at different environmental temperatures in experimental myocardial necrosis. ( Ahmad, M; Tajuddin, M; Tariq, M, 1975)
"Circulating prolactin levels were monitored in nonarteriosclerotic, arteriosclerotic, and hormonally sterilized male and female Sprague-Dawley rats during the acute necrosis and repair phases of myocardial infarction induced by isoproterenol."3.65Serum prolactin levels in rats following isoproterenol-induced myocardial infarction. ( Lewis, BK; Wexler, BC, 1975)
"Isoproterenol (ISO), a drug which causes an increased strength of myocardial contraction when administered to animals in mug/kg doses, causes myocardial necrosis when given mg/kg doses."3.65Calcium as mediator of isoproterenol-induced myocardial necrosis. ( Bloom, S; Davis, DL, 1972)
"Modern medicine has been used to treat myocardial infarction, a subset of cardiovascular diseases, and have been relatively effective but not without adverse effects."2.55Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review. ( Ramamurthy, S; Thanikachalam, PV; Wong, ZW, 2017)
"Cardiogenic shock is a relatively specific clinical syndrome characterized by decreased cardiac output, elevated left ventricular filling pressure, and arterial hypotension with vital organ hypoperfusion."2.36Pharmacologic support in cardiogenic shock. ( Rude, RE, 1983)
"Scopoletin pre-treatment with ISO (25 and 50 mg/kg b."1.91Cardioprotective Role of Scopoletin on Isoproterenol-Induced Myocardial Infarction in Rats. ( Ibrahim, IAA; Rong, N; Yang, R; Zhang, W, 2023)
"Protocatechuic acid (PCA) is a polyphenolic compound with various potent biological activities."1.91Protocatechuic acid reverses myocardial infarction mediated by β-adrenergic agonist via regulation of Nrf2/HO-1 pathway, inflammatory, apoptotic, and fibrotic events. ( Elhefny, MA; Jiang, H; Kassab, RB; Li, L; Lokman, MS; Ma, H; Sberi, HA; Xia, B; Zhang, Y, 2023)
"The cardiac mitochondrial damage and cardiac hypertrophy pathways are intimately associated with the pathology of myocardial infarction (MI)."1.91Protective effects of β-caryophyllene on mitochondrial damage and cardiac hypertrophy pathways in isoproterenol-induced myocardial infarcted rats. ( Ponnian, SMP; Stanely, SP; Yovas, A, 2023)
"Isoproterenol (ISO) was used to induce MI injury in mice and H9c2 cells."1.91Curdione inhibits ferroptosis in isoprenaline-induced myocardial infarction via regulating Keap1/Trx1/GPX4 signaling pathway. ( Cheng, Y; Liang, Q; Liu, Z; Shi, S; Wang, H; Xie, B; Zhang, R, 2023)
"Pre-treatment of fraxetin in group IV experimental rats resulted in decreased cardiac weight, diminished level of cardiac markers (cardiac troponin T (cTnT), creatine kinase, creatine kinase-MB, and cardiac troponin I (cTnI)), reduced level of oxidative stress biomarkers (LOOH and TBARS) in the plasma and cardiac tissue, amplified level of enzymes in antioxidant defense system (catalase (CAT), superoxide dismutase (SOD), glutathione (GSH), and glutathione peroxidase (GPx)) in the plasma and heart tissue, and elevated level of ATPase activities."1.72Effect of Fraxetin on Oxidative Damage Caused by Isoproterenol-Induced Myocardial Infarction in Rats. ( Chen, G; Wang, L; Yin, Y; You, H, 2022)
"Control of hyperlipidemia is believed to reduce major cardiovascular events such as cardiovascular death, myocardial infarction, nonfatal stroke, hospitalization for unstable angina, and coronary revascularization."1.72The effect of bempedoic acid an ATP-citrate lyase inhibitor on cardiovascular risk factors in rats with experimentally induced myocardial infarction and hyperlipidemia. ( Mohammed Ali, N; Yaseen, MS, 2022)
"Visnagin (VIS) is a natural bioactive component of Ammi visnaga, with promising radical scavenging and anti-inflammatory activities."1.62Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats. ( Abukhalil, MH; Al-Amarat, W; Al-Swailmi, FK; Aladaileh, SH; Alanazi, KM; Alfwuaires, MA; Algefare, AI; Althunibat, OY; Hussein, OE; Kamel, EM; Mahmoud, AM; Saghir, SA, 2021)
"Ferruginol (FGL) is a major polyphenols and terpenoids with numerous pharmacological activities including antioxidant and anti-inflammatory."1.62Ameliorative effect of ferruginol on isoprenaline hydrochloride-induced myocardial infarction in rats. ( Ali Alharbi, S; Chen, Y; Deng, Y; Feng, J; Li, H; Li, X; Wang, C; Wang, L; Zhang, X, 2021)
" The ß-adrenergic agonist isoproterenol hydrochloride is used for its cardiac effects in a variety of different dosing regimens with high doses causing acute cardiomyocyte necrosis."1.62Type 2 MI induced by a single high dose of isoproterenol in C57BL/6J mice triggers a persistent adaptive immune response against the heart. ( Baxan, N; Bedard, O; Benson, L; Boyle, JJ; Branca, J; Forte, E; Harding, SE; Hasham, MG; Ng, FS; Panahi, M; Rosenthal, N; Sattler, S, 2021)
" For pharmacodynamic study, histopathological and biochemical analysis were performed to assess the anti-myocardial ischemic effects."1.56Pharmacodynamics and pharmacokinetics of Danshen in isoproterenol-induced acute myocardial ischemic injury combined with Honghua. ( Bai, JQ; Chen, YY; Duan, JA; Liu, F; Qu, C; Shen, LF; Tang, YP; Wang, XP; Xu, DQ; Yue, SJ; Zhao, BC; Zhou, GS, 2020)
"Memantine treatment reduced the expression of cardiac TNF-α in comparison to Iso group."1.56Cardioprotective effects of memantine in myocardial ischemia: Ex vivo and in vivo studies. ( Abbaszadeh, S; Jannesar, K; Malekinejad, H; Soraya, H, 2020)
" This dosing schedule caused daily drug-free periods of at least 6 h as evidenced by propranolol plasma concentrations and cardiac β-adrenergic responsiveness."1.56Intermittent β-adrenergic blockade downregulates the gene expression of β-myosin heavy chain in the mouse heart. ( Ambrosio, C; Barbagallo, F; Catalano, L; Grò, MC; Maccari, S; Marano, G; Matarrese, P; Molinari, P; Pace, V; Patrizio, M; Rizzi, R; Stati, T; Vezzi, V, 2020)
"Ginkgolides are widely used in cardio-protective therapy; however, poor bioavailability currently limits their application."1.56Preparation of Ginkgolide Solid Dispersions with Low-Molecular-Weight Chitosan and Assessment of their Protective Effect on Isoproterenol- Induced Myocardial Injury. ( Cui, L; Ding, W; Liu, B; Liu, D; Xia, Z; Zhang, L, 2020)
"Piperine pretreatment significantly prevented these changes in ISO treated group."1.56The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity. ( Aliev, G; Beeraka, NM; Chubarev, VN; Dhivya, V; Gavryushova, LV; Huang, CY; Mikhaleva, LM; Minyaeva, NN; Tarasov, VV; Viswanadha, VP, 2020)
"Raspberry ketone (RK) is a red raspberry (Rubusidaeus, Family-Rosaceae) plant constituent, which activates PPAR-α."1.51Suppression of isoproterenol-induced cardiotoxicity in rats by raspberry ketone via activation of peroxisome proliferator activated receptor-α. ( Bhandari, U; Haque, SE; Khan, V; Rishi, V; Sharma, N; Sharma, S, 2019)
"Pretreatment with nimodipine (10 and 15 mg/kg, i."1.51Effects of nimodipine, vinpocetine and their combination on isoproterenol-induced myocardial infarction in rats. ( Ansari, MA; Ekbbal, R; Haque, SE; Iqubal, A, 2019)
"Diosmin pretreatment showed significant preventive effects on all the biochemical parameters, and the structure of mitochondria was evaluated."1.48Diosmin Prevents Isoproterenol-Induced Heart Mitochondrial Oxidative Stress in Rats. ( John, B; Sharmila Queenthy, S; Stanely Mainzen Prince, P, 2018)
"Zingerone pretreatment revealed significant (P<0."1.48A molecular mechanism on the antiapoptotic effects of zingerone in isoproterenol induced myocardial infarcted rats. ( Hemalatha, KL; Stanely Mainzen Prince, P, 2018)
"Pretreatment with kaempferol at highest dose showed mild mononuclear infiltration and degenerative changes in heart tissue section of myocardial injured rats."1.48Effect of Kaempferol Pretreatment on Myocardial Injury in Rats. ( Kandasamy, A; Kumar, A; Kumar, D; Kumar, T; Lingaraju, MC; Parida, S; Rungsung, S; Singh, TU; Vishwakarma, A, 2018)
"Levosimendan has vasorelaxant and anti-aggregatory properties."1.48Cardioprotective and Anti-Aggregatory Effects of Levosimendan on Isoproterenol-Induced Myocardial Injury in High-Fat-Fed Rats Involves Modulation of PI3K/Akt/mTOR Signaling Pathway and Inhibition of Apoptosis: Comparison to Cilostazol. ( El-Kherbetawy, MK; Makary, S; Tawfik, MK, 2018)
" At the end of dosing left ventricular functions was assessed to estimate its effect on cardiac functions."1.46Cardiaprotective effect of crocetin by attenuating apoptosis in isoproterenol induced myocardial infarction rat model. ( Ge, Z; Li, Y; Zhang, W, 2017)
"During arrhythmia provocation induced by catecholamine injections, TG animals were resistant to triggered ventricular arrhythmias."1.46Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction. ( Brunner, FJ; Dewenter, M; El-Armouche, A; Fischmeister, R; Geerts, A; Hoffmann, M; Karam, S; Lämmle, S; Lechêne, P; Leroy, J; Lindner, M; Lorenz, K; Mason, FE; Mehel, H; Meinecke, S; Riedel, M; Schanbacher, C; Sossalla, S; Vandecasteele, G; Vettel, C; Wagner, M; Wieland, T; Wunder, F, 2017)
"Piperine pre-treatment decreased the levels of serum markers, lipid peroxidation and PCC with increased antioxidant status in the heart tissues of ISO administered rats."1.46Piperine modulates isoproterenol induced myocardial ischemia through antioxidant and anti-dyslipidemic effect in male Wistar rats. ( Chirayil, HT; Dhivya, V; Huang, CY; Padma, VV; Priya, LB; Sathiskumar, S, 2017)
"Acute myocardial infarction is a serious acute cardiac disorder and heart disease is still a major public health problem in adults."1.43Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats. ( Akcilar, R; Altuntas, I; Bayat, Z; Isiklar, OO; Kocak, C; Kocak, FE; Kocak, H; Simsek, H; Taser, F, 2016)
"Myocardial infarction was induced into rats by the subcutaneous administration of isoproterenol (100mg/kg body weight) at an interval of 24h daily for a period of two days (7th and 8th day)."1.43Activation of β1-adrenoceptor triggers oxidative stress mediated myocardial membrane destabilization in isoproterenol induced myocardial infarcted rats: 7-hydroxycoumarin and its counter action. ( Jagadeesh, GS; Nagoor Meeran, MF; Selvaraj, P, 2016)
"Isorhapontigenin is a derivative of stilbene with chemical structure similar to resveratrol."1.43Cardioprotective effect of resveratrol analogue isorhapontigenin versus omega-3 fatty acids in isoproterenol-induced myocardial infarction in rats. ( Abbas, AM, 2016)
"Pre-treatment with ibuprofen (30, 60 and 90mg/kg p."1.43Inhibition of RhoA/Rho kinase by ibuprofen exerts cardioprotective effect on isoproterenol induced myocardial infarction in rats. ( Gandhi, T; Parikh, M; Patel, P; Shah, H, 2016)
"Zingerone pretreatment significantly (P<0."1.43Anti-inflammatory and anti-thrombotic effects of zingerone in a rat model of myocardial infarction. ( Hemalatha, KL; Stanely Mainzen Prince, P, 2016)
"Pretreatment with zingerone daily for 14 days revealed significant preventive effects on the electrophoretic and biochemical parameters evaluated in isoproterenol-induced rats."1.42Preventive effects of zingerone on altered lipid peroxides and nonenzymatic antioxidants in the circulation of isoproterenol-induced myocardial infarcted rats. ( Hemalatha, KL; Prince, PS, 2015)
"Pretreatment with zingerone (vanillyl acetone) revealed preventive effects on tachycardia, LVH, ECG, and all the above mentioned biochemical parameters evaluated in isoproterenol induced myocardial infarcted rats."1.42A biochemical and 2, 3, 5-triphenyl tetrazolium chloride staining study on the preventive effects of zingerone (vanillyl acetone) in experimentally induced myocardial infarcted rats. ( Hemalatha, KL; Stanely Mainzen Prince, P, 2015)
"Pretreatment with zingerone prevented hyperlipidaemia and cardiac hypertrophy, by virtue of its antihyperlipidaemic, antihypertrophic, and reducing properties in isoproterenol-induced myocardial infarcted rats."1.42Antihyperlipidaemic, antihypertrophic, and reducing effects of zingerone on experimentally induced myocardial infarcted rats. ( Hemalatha, KL; Stanely Mainzen Prince, P, 2015)
"In isoproterenol-treated rats, Zn(ASA)2 treatment normalized significantly impaired left-ventricular contractility index (Emax 2."1.42Superiority of zinc complex of acetylsalicylic acid to acetylsalicylic acid in preventing postischemic myocardial dysfunction. ( Atmanli, A; Barnucz, E; Hegedűs, P; Hirschberg, K; Karck, M; Korkmaz, S; Li, S; Loganathan, S; Radovits, T; Szabó, G; Yasui, H; Yoshikawa, Y, 2015)
"Myocardial infarction is one of the major public concerns in both developed and developing countries."1.42Dietary Chitosan Supplementation Ameliorates Isoproterenol-Induced Aberrations in Membrane-Bound ATPases and Mineral Status of Rat Myocardium. ( Anandan, R; Asha, KK; Chatterjee, NS; Ganesan, B; Mathew, S; Sivakumar, R, 2015)
"Isoproterenol (ISO) has been reported to inhibit high mobility group box 1 (HMGB1) protein release via heme oxygenase-1 (HO-1) induction in lipopolysaccharide (LPS)-activated RAW 264."1.40Isoproterenol‑mediated heme oxygenase‑1 induction inhibits high mobility group box 1 protein release and protects against rat myocardial ischemia/reperfusion injury in vivo. ( Fu, W; Hu, X; Jiang, H; Wang, J; Xie, J; Zhou, X, 2014)
"Myocardial infarction (MI; "heart attack") can cause injury to or death of heart muscle tissue (myocardium) owing to prolonged ischemia and hypoxia."1.40Elevated adropin: a candidate diagnostic marker for myocardial infarction in conjunction with troponin-I. ( Aydin, S; Çakmak, T; Eren, MN; Kalayci, M; Kuloglu, T; Yilmaz, M, 2014)
"Hesperidin has been shown to possess cardioprotective and anti-diabetic potential."1.40Hesperidin blunts streptozotocin-isoproternol induced myocardial toxicity in rats by altering of PPAR-γ receptor. ( Agrawal, YO; Arya, DS; Goyal, SN; Sharma, PK; Shrivastava, B, 2014)
"Myocardial infarction was manifested by a significant elevation in the level of CK-MB and histopathological findings in isoprenaline group when compared to controls."1.40The plant histaminase: a promising enzyme with antioxidant properties versus histamine release in isoprenaline-induced myocardial infarction in rats. ( Alirezaei, M; Delfan, B; Dezfoulian, O; Divekan, H; Kheradmand, A; Khonsari, A; Rashidipour, M, 2014)
"Treatment with tamoxifen significantly controlled dyslipidemia, hypertension, bradycardia, oxidative stress, and reduced serum cardiac markers."1.40Beneficial role of tamoxifen in isoproterenol-induced myocardial infarction. ( Patel, BM; Rayabarapu, N, 2014)
"Isoproterenol (100 mg/kg) was injected subcutaneously for two consecutive days to induce myocardial infarction, and simultaneously tacrolimus was administered orally twice a day for three days."1.40Tacrolimus ameliorates functional disturbances and oxidative stress in isoproterenol-induced myocardial infarction. ( Garjani, A; Garjani, M; Hammami, M; Khorrami, A; Maleki-Dizaji, N, 2014)
"Rats treated with isoproterenol (ISO, 85 mg/kg, sc, twice at an interval of 24 h) showed a significant increase in heart rate, mean arterial blood pressure, pressure rate index, ST elevation on ECG, and a significant increase in the levels of cardiac marker enzymes- lactate dehydrogenase, and creatine kinase in serum and a significant reduction in superoxide dismutase, and catalase and increase in thiobarbituric acid reactive substance activity in heart tissue."1.39Intravenous human umbilical cord blood improves electrophysiological and metabolic properties in ISO induced myocardial necrosis in rats. ( Kasturet, S; Mohan, M; Rokade, R, 2013)
"Then isoproterenol (100mg/kg) was injected subcutaneously into rats at an interval of 24h for 2 days (on 11th and 12th day)."1.39Diosmin exhibits anti-hyperlipidemic effects in isoproterenol induced myocardial infarcted rats. ( John, B; Queenthy, SS, 2013)
"Isoproterenol treatment caused significant increase in mitochondrial lipid peroxides and lipids except phospholipids with significant decrease in mitochondrial antioxidants."1.39An in vivo and in vitro study on the protective effects of N-acetylcysteine on mitochondrial dysfunction in isoproterenol treated myocardial infarcted rats. ( Basha, RH; Priscilla, DH, 2013)
"Metoprolol can inhibit the expression of c-fos and has a positive therapeutic effect on rats after AMI; the involvement effect of metoprolol on myocardial infarction might be correlated with its effect on the inhibition of c-fos."1.39The effect of c-fos on acute myocardial infarction and the significance of metoprolol intervention in a rat model. ( Ge, J; Goldstein, S; He, B; Li, Y; Ruiz, G; Zhang, M; Zhang, S, 2013)
"Pre-treatment with morin favorably restored the biochemical and functional parameters to near normal indicating morin to be a significant protective effect on cardiac mitochondrial function against ISO-induced MI in rats."1.38Protective effect of morin on cardiac mitochondrial function during isoproterenol-induced myocardial infarction in male Wistar rats. ( Al Numair, KS; Alsaif, MA; Baskar, AA; Chandramohan, G, 2012)
"Pretreatment with morin regulated the abnormalities in electrocardiograph and biomarkers."1.38Morin protects heart from beta-adrenergic-stimulated myocardial infarction: an electrocardiographic, biochemical, and histological study in rats. ( Arella, M; Boini, L; Maharajan, MK; Oddepalli, DR; Pogula, BK; Sabarimuthu, DQ, 2012)
"Isoproterenol (ISO) was used to induce AMI."1.38Increased expression of calcium-sensing receptors in atherosclerosis confers hypersensitivity to acute myocardial infarction in rats. ( Guo, J; Li, GW; Li, HZ; Wang, LC; Wang, R; Xing, WJ; Xu, CQ; Zhang, WH, 2012)
"Acute myocardial infarction was induced by injecting the rats with two doses of isoproterenol (85 mg/kg/24 h, s."1.38Rosuvastatin promotes angiogenesis and reverses isoproterenol-induced acute myocardial infarction in rats: role of iNOS and VEGF. ( Abo-Gresha, NM; Zaitone, SA, 2012)
"Gliclazide or saline was given q12 h for 48 h to rats received isoprenaline."1.38Blockers of sulfonylureas receptor 1 subunits may lead to cardiac protection against isoprenaline-induced injury in obese rats. ( Bao, Y; Shuyuan, L; Sun, X; Yang, W; Yerong, Y, 2012)
"Myocardial ischemia was induced by subcutaneous injection of ISO (85 mg/kg BW) twice at an interval of 24 h, for two consecutive days."1.38Effect of ursolic acid on cardiac marker enzymes, lipid profile and macroscopic enzyme mapping assay in isoproterenol-induced myocardial ischemic rats. ( Pugalendi, KV; Radhiga, T; Rajamanickam, C; Senthil, S, 2012)
"Sesamol is a potent phenolic antioxidant contained only in processed sesame oil and possesses potent chemopreventive, antimutagenic, antihepatotoxic and antioxidation properties."1.38Efficacy of sesamol on plasma and tissue lipids in isoproterenol-induced cardiotoxicity in Wistar rats. ( Pugalendi, KV; Vennila, L, 2012)
"Vanillic acid pretreated isoproterenol-induced rats positively altered all the above-mentioned biochemical parameters."1.37Preventive effects of vanillic acid on lipids, bax, bcl-2 and myocardial infarct size on isoproterenol-induced myocardial infarcted rats: a biochemical and in vitro study. ( Dhanasekar, K; Prince, PS; Rajakumar, S, 2011)
"Isoproterenol (2 mg/kg, IP) was administered daily for 7 days."1.37An oral formulation of angiotensin-(1-7) produces cardioprotective effects in infarcted and isoproterenol-treated rats. ( Almeida, AP; Caliari, MV; Ferreira, AJ; Irigoyen, MC; Jacoby, BA; Marques, FD; Melo, MB; Nadu, AP; Santos, RA; Silva, GA; Sinisterra, RD; Sousa, FB; Souza, LE, 2011)
"Pretreatment with ellagic acid restored the activities of lysosomal enzymes and membrane bound ATPases."1.37Pharmacodynamics of ellagic acid on cardiac troponin-T, lyosomal enzymes and membrane bound ATPases: mechanistic clues from biochemical, cytokine and in vitro studies. ( Darlin Quine, S; Mari Kannan, M, 2011)
"Myocardial infarction affects a large population in the world."1.36Protective effect of caffeic acid on cardiac markers and lipid peroxide metabolism in cardiotoxic rats: an in vivo and in vitro study. ( Kumaran, KS; Prince, PS, 2010)
"Melatonin has virtually no toxicity which raises the possibility of this indole being a therapeutic treatment for ischemic heart disease."1.36Melatonin protects against isoproterenol-induced myocardial injury in the rat: antioxidative mechanisms. ( Bandyopadhyay, A; Bandyopadhyay, D; Basu, A; Chattopadhyay, A; Ghosh, AK; Mitra, E; Mukherjee, D; Reiter, RJ; Roy, SG, 2010)
"Verapamil response was significantly correlated with cTnI."1.36Drug-disease interaction: reduced verapamil response in isoproterenol-induced myocardial injury in rats. ( El-Kadi, AO; Hanafy, S; Jamali, F, 2010)
"Myocardial infarction was produced in rats with 65, 85, 120 and 200mg/kg of ISO administered subcutaneously (sc) twice at an interval of 24h."1.35Cardioprotective activity of Ginkgo biloba Phytosomes in isoproterenol-induced myocardial necrosis in rats: a biochemical and histoarchitectural evaluation. ( Naik, SR; Panda, VS, 2008)
"Myocardial infarction is the number one killer disease in many parts of the world."1.35Cardioprotective effect of 'Marutham' a polyherbal formulation on isoproterenol induced myocardial infarction in Wistar rats. ( Devika, PT; Prince, PS; Suman, S; Vaithianathan, M, 2008)
"Melatonin has potent cardioprotective properties."1.35Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions. ( Genade, S; Genis, A; Huisamen, B; Lochner, A; Ytrehus, K, 2008)
"Pretreatment with mangiferin (100 mg/kg body weight, intraperitoneally) for 28 days, significantly prevented the alterations and restored the enzyme activities to near-normal status."1.35Mechanism of protective action of mangiferin on suppression of inflammatory response and lysosomal instability in rat model of myocardial infarction. ( Devi, CS; Narayan, S; Prabhu, S, 2009)
"Myocardial infarction was experimentally induced with ISO (85 mg/kg) twice at 24 h interval."1.35Antilipoperoxidative and membrane stabilizing effect of diosgenin, in experimentally induced myocardial infarction. ( Jayachandran, KS; Rajamanickam, GV; Vasanthi, HR, 2009)
"Myocardial infarction was induced by subcutaneous injection of ISO (150 mg/kg) once a day for 2 days."1.35Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study. ( Darlin Quine, S; Sangeetha, T, 2009)
"Pretreatment with betaine daily for a period of 30 days to isoprenaline-induced rats prevented the changes in the activities of these lysosomal enzymes."1.35Protective effect of betaine on changes in the levels of lysosomal enzyme activities in heart tissue in isoprenaline-induced myocardial infarction in Wistar rats. ( Anandan, R; Ganesan, B, 2009)
"Pretreatment with gallic acid (15 mg/kg) to isoproterenol treated rats significantly (P<0."1.35Gallic acid prevents lysosomal damage in isoproterenol induced cardiotoxicity in Wistar rats. ( Devika, PT; Priscilla, H; Stanely Mainzen Prince, P, 2009)
"Isoproterenol treatment (80 mg/kg given over 2 days in two equal doses) caused arrhythmias and 60% mortality within 24 h of the last injection in the control group (C + ISO) group when compared with the saline control group (saline)."1.35Exercise training provides cardioprotection via a reduction in reactive oxygen species in rats submitted to myocardial infarction induced by isoproterenol. ( Barbosa, VA; Boeck, CR; Da Luz, G; Da Silva, S; De Pinho, RA; De Souza, CT; Frederico, MJ; Justo, SL; Medeiros, C; Silva, LA, 2009)
"Amiodarone was administered to groups of rats once per day for 30 days."1.35Preventive effect of amiodarone during acute period in isoproterenol-induced myocardial injury in Wistar rats. ( Albayrak, F; Bakan, E; Bayir, Y; Bayram, E; Halici, Z; Kabalar, E; Keles, MS; Kurt, M; Ozturk, C; Suleyman, H, 2009)
"Myocardial infarction was induced in rats by subcutaneous injection of isoproterenol (ISO) (150 mg kg(-1)) at an interval of 24 h for 2 days."1.35Protective effect of S-allyl cysteine sulphoxide (alliin) on glycoproteins and hematology in isoproterenol induced myocardial infarction in male Wistar rats. ( Quine, SD; Sangeetha, T, 2008)
" By 48 hours the hearts of rats dosed with 125-500 mug/kg Iso had developed interstitial fibrosis, and serum cTnT had declined to near control levels (0."1.35Isoproterenol-induced cardiotoxicity in sprague-dawley rats: correlation of reversible and irreversible myocardial injury with release of cardiac troponin T and roles of iNOS in myocardial injury. ( Herman, EH; Knapton, A; Lipshultz, SE; Weaver, JL; Zhang, J, 2008)
"Isoproterenol (ISO) has been found to cause severe injury in the myocardium."1.35Protective effects of N-acetylcysteine in isoproterenol-induced myocardium injury in rats. ( Fu, J; Li, H; Li, W; Li, Y; Liu, B; Liu, P; Wang, Z, 2009)
"Rats with congestive heart failure (CHF) develop ventricular inotropic responsiveness to serotonin (5-HT), mediated through 5-HT(2A) and 5-HT(4) receptors."1.34Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes. ( Birkeland, JA; Enger, U; Levy, FO; Lunde, PK; Qvigstad, E; Sejersted, OM; Sjaastad, I; Swift, F; Tovsrud, N, 2007)
"Carvedilol is a combined alpha(1)- and beta-adrenoceptor antagonist."1.33Carvedilol blockade of alpha1- and beta-adrenoceptor induced inotropic responses in rats with congestive heart failure. ( Bøkenes, J; Osnes, JB; Qvigstad, E; Schiander, I; Sejersted, OM; Sjaastad, I; Skomedal, T; Solberg, L, 2005)
"Isoproterenol treatment of first passage scar myofibroblasts increased protein synthesis and induced BNP mRNA expression, whereas ANP mRNA levels remained unchanged."1.33Scar myofibroblasts of the infarcted rat heart express natriuretic peptides. ( Bel-Hadj, S; Calderone, A; Clement, R; Drapeau, J; El-Helou, V; Gosselin, H; Villeneuve, L, 2006)
"An arrhythmia was identified as preceding the syncope in 27 patients (45%): ventricular tachycardia (VT) n = 16, supraventricular tachycardia (n = 5), 2nd or 3rd degree AV block (n = 3), vaso-vagal reaction (n = 3): 3 subjects developed coronary ischaemia."1.33[Significance of isuprel infusion in unexplained syncope after myocardial infarction]. ( Belhakem, H; Brembilla-Perrot, B; Claudon, O; Ernst, Y; Louis, P; Muhanna, I; Nippert, M; Selton, O; Terrier de la Chaise, A, 2006)
"Pretreatment with mangiferin (100 mg/kg b."1.33Effect of mangiferin on mitochondrial energy production in experimentally induced myocardial infarcted rats. ( Jainu, M; Prabhu, S; Sabitha, KE; Shyamala Devi, CS, 2006)
" AEC was administered orally to male albino rats (150-200 g), at a dosage of 0."1.33Pretreatment with alcoholic extract of Crataegus oxycantha (AEC) activates mitochondrial protection during isoproterenol - induced myocardial infarction in rats. ( Devaraj, SN; Jayalakshmi, R; Thirupurasundari, CJ, 2006)
"Isoproterenol-treated rats showed lower maximal rate of increase and decrease of left-ventricle pressure development (+/-left-ventricle dp/dtmax) and higher left-ventricle end-diastolic pressure (all P<0."1.33Intermedin1-53 protects the heart against isoproterenol-induced ischemic injury in rats. ( Chang, JK; Geng, B; Gerns, H; Jia, YX; Pan, CS; Qi, YF; Tang, CS; Wen, JK; Xiao, Y; Yang, J; Yang, JH; Zhang, J; Zhao, J, 2006)
"Myocardial infarction was induced in rats by occluding the left coronary artery for 8 and 24 weeks."1.33Differential changes in beta-adrenoceptor signal transduction in left and right ventricles of infarcted rats. ( Babick, A; Dhalla, NS; Elimban, V; Saini, HK; Sethi, R; Wang, X, 2006)
"Because heart failure is a progressive disease that often evolves from hypertrophy, we analyzed the RyR2 macromolecular complex in several animal models of cardiomyopathy that lead to heart failure, including hypertrophy, and at different stages of disease progression."1.32Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol. ( Burkhoff, D; D'Armiento, J; Gaburjakova, M; Gomez, AM; Guatimosim, S; Lederer, WJ; Marks, AR; Reiken, S; Vassort, G; Wang, J, 2003)
"The isoproterenol-stimulated increase in I Ca(L) was significantly smaller in postinfarction myocytes (Emax: 63."1.32Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure. ( Chedid, NG; Díaz G, LE; Masuda, MO; Quintero H, CC; Saraiva, RM, 2003)
"A suppression of arrhythmia by Pro and CPU86017 resulted from a regression of the dispersion and depression of RyR2 and SERCA2."1.32Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats. ( Dai, DZ; Gao, E; Lu, F; Wang, HL; Zhang, YP, 2004)
" Ws on chronic administration markedly augmented antioxidants (GSH, GSHPx, SOD, CAT) while Vit E did not stimulate the synthesis of endogenous antioxidants compared to sham."1.32Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment. ( Arya, DS; Bansal, P; Dinda, A; Gupta, SK; Joshi, S; Mohanty, I; Saxena, A; Talwar, KK, 2004)
"Moreover, scar size was significantly smaller (16 +/- 6% vs."1.32Treatment of acute myocardial infarction by hepatocyte growth factor gene transfer: the first demonstration of myocardial transfer of a "functional" gene using ultrasonic microbubble destruction. ( Fuke, S; Kohno, M; Kondo, I; Namba, T; Noma, T; Ohmori, K; Oshita, A; Shinomiya, K; Takeuchi, H, 2004)
"Pretreatment with propranolol or labetalol counteracted the appearance of the myocardial histological alterations and the associated ECG and biochemical lesions."1.32Isoproterenol-induced myocardial infarction in rabbits. Protection by propranolol or labetalol: a proposed non-invasive procedure. ( Accinni, R; Bonacina, E; Brenna, S; Pinelli, A; Tomasoni, L; Trivulzio, S, 2004)
"Since heart failure is also associated with attenuated responses to catecholamines, we examined the effects of imidapril, an ACE inhibitor, on the beta-adrenoceptor (beta-AR) signal transduction in the failing heart."1.32Changes in beta-adrenoceptors in heart failure due to myocardial infarction are attenuated by blockade of renin-angiotensin system. ( Dhalla, NS; Ren, B; Saini, HK; Sethi, R; Shao, Q; Takeda, N, 2004)
"Myocardial infarction is usually induced in small animals by means of invasive procedures: the aim of this study was to cause heart necrosis lesions by non-invasive means."1.32Myocardial infarction non-invasively induced in rabbits by administering isoproterenol and vasopressin: protective effects exerted by verapamil. ( Bertolini, B; Bonacina, E; Brenna, S; Pinelli, A; Tomasoni, L; Trivulzio, S; Vignati, S, 2004)
"Ischemia-induced ventricular arrhythmias were mostly reduced."1.31Reduction of infarct size by selective stimulation of prostaglandin EP(3)receptors in the reperfused ischemic pig heart. ( Hohlfeld, T; Meyer-Kirchrath, J; Schrör, K; Vogel, YC, 2000)
"Heart failure is associated with alterations in contractile parameters and accompanied by abnormalities in intracellular calcium homeostasis."1.31Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity. ( Bøkenes, J; Christensen, G; Hoen, IB; Holt, E; Lunde, PK; Sande, JB; Sjaastad, I; Tønnessen, T, 2002)
"Acute myocardial infarction is the second cause of mortality in most countries, therefore, it is important to know the evolution and sequence of the physiological and biochemical changes involved in this pathology."1.30Sequential changes of energy metabolism and mitochondrial function in myocardial infarction induced by isoproterenol in rats: a long-term and integrative study. ( Aranda-Fraustro, A; Chagoya de Sánchez, V; Cota-Garza, MD; Cruz, D; Hernández-Muñoz, R; López-Barrera, F; Suárez, J; Vidrio, S; Yañez, L, 1997)
"The propranolol treated animals had higher LV end-diastolic pressures (27+/-2* vs 20+/(-3 mmHg) and a more restricted LV diastolic filling pattern (increased ratio of early to late filling velocities and more rapid E wave deceleration rate)."1.30Effects of propranolol treatment on left ventricular function and intracellular calcium regulation in rats with postinfarction heart failure. ( Douglas, PS; Katz, SE; Litwin, SE; Morgan, JP, 1999)
"Mibefradil treatment increased MAP and dP/dtmax and decreased LVEDP and HR in infarcted rats."1.30Effects of the calcium channel antagonist mibefradil on haemodynamic parameters and myocardial Ca(2+)-handling in infarct-induced heart failure in rats. ( Meissner, A; Min, JY; Sandmann, S; Unger, T, 1999)
"Isoproterenol was used as a drug which, when administered in high doses, is able to induce lysosomal enzyme activity changes in in vivo conditions."1.30Comparison of isoproterenol-induced changes in lysosomal enzyme activity in vivo and in vitro. ( Horáková, K; Macicková, T; Navarová, J; Urbancíkova, M, 1999)
"Nisoldipine was more effective in preventing cardiac necrosis as compared to nitrendipine and nimodipine."1.29Effect of nitrendipine, nimodipine and nisoldipine on experimentally induced myocardial infarction in rats. ( Kaur, AH; Mathur, SK; Singh, J; Srivastava, RK, 1995)
"Acute myocardial infarction was induced in New Zealand male albino rabbits."1.29Oligotide, a new single-stranded oligodeoxyribonucleotide, preserves postsynaptic beta-adrenergic and cholinergic receptor functions in rabbit hearts after acute infarction. ( Bernareggi, M; Berti, F; Berti, M; Ferro, L; Pescador, R; Porta, R; Rossoni, G; Trento, F, 1995)
"The resulting necrosis is believed to result, at least in part, from the leakage of lysosomal enzymes into the cytoplasm."1.29Isoproterenol-induced redistribution of endosomes in cardiac myocytes. ( Gruenberg, J; Marjomäki, V; Ritamäki, V, 1994)
"Pretreatment with oxodipine significantly reduced the infarct size in the apical and basal myocardium (P < 0."1.29Effects of oxodipine and nitrendipine on the size of experimental myocardial infarct in the rat. ( Gil-Loyzaga, P; Merchàn-Pérez, A; Pérez-Cao, A; Tamargo, J, 1994)
"Regional myocardial ischemia is associated with increased levels of adenosine and norepinephrine, factors that may alter activation of the beta-adrenergic receptor (beta AR)-G protein-adenylyl cyclase pathway in the heart."1.29Regional myocardial downregulation of the inhibitory guanosine triphosphate-binding protein (Gi alpha 2) and beta-adrenergic receptors in a porcine model of chronic episodic myocardial ischemia. ( Hammond, HK; McKirnan, MD; Ping, P; Roth, DA, 1993)
"Aspirin treatment is found to counteract the effect of isoproterenol on lipid and lipid peroxide formation and associated enzyme changes in heart mitochondria."1.29Effect of aspirin on mitochondrial lipids in experimental myocardial infarction in rats. ( Devi, CS; Manjula, TS, 1993)
"Rats treated with isoproterenol (30 mg/100 g body weight) showed a significant increase in serum lysosomal hydrolase activities, which were found to decrease after curcumin treatment."1.29Effect of curcumin on certain lysosomal hydrolases in isoproterenol-induced myocardial infarction in rats. ( Nirmala, C; Puvanakrishnan, R, 1996)
"Curcumin pre- and co-treatment decreased the severity of pathological changes and thus, could have a protective effect against the damage caused by myocardial infarction (MI)."1.29Protective role of curcumin against isoproterenol induced myocardial infarction in rats. ( Nirmala, C; Puvanakrishnan, R, 1996)
"Isoproterenol was titrated to achieve a heart rate of 130% of baseline."1.28Autonomic manipulation influences both temporal and frequency analyses of late potentials. ( Caracciolo, E; Chinitz, L; Demopoulos, L; Perez, J; Schrem, S; Schwartzman, D; Slater, W, 1992)
"Treatment with captopril for 5 weeks, beginning 1 week after infarction (n = 14), resulted in reduction of left ventricular filling pressures and partial normalization of myocardial contractility and Ca2+i handling."1.28Captopril enhances intracellular calcium handling and beta-adrenergic responsiveness of myocardium from rats with postinfarction failure. ( Litwin, SE; Morgan, JP, 1992)
"Aspirin treated rats showed marked reversal of these metabolic changes."1.28Effect of aspirin on serum lipoprotein profile in rats subjected to myocardial stress by isoproterenol. ( Devi, CS; Manjula, TS; Prema, A, 1992)
"Thus, triggered arrhythmias dependent upon adrenergic stimulation can either be potentiated or inhibited by the biochemical derangements of acute ischemia."1.28[Variations in arrhythmogenic response to catecholamines in acute myocardial ischemia]. ( Corr, PB; Priori, SG, 1991)
"Aspirin treated rats showed lower mortality rate and smaller changes in the myocardium on histopathological examination when compared to corresponding animals given isoproterenol alone."1.28Protective action of aspirin in experimental myocardial infarction induced by isoproterenol in rats and its effect on lipid peroxidation. ( Menon, VP; Muraleedharan, D; Sushama Kumari, S; Varghese, A, 1990)
"Myocardial infarction was produced by ligating the left main coronary artery."1.27Effects of chronic myocardial infarction on responsiveness to isoprenaline and the state of myocardial beta adrenoceptors in rats. ( Burkard, W; Clozel, JP; Da Prada, MD; Holck, M; Osterrieder, W, 1987)
"This hypokalemia is not mediated by insulin, renin or aldosterone."1.27Hypokalemia from beta 2-receptor stimulation by circulating epinephrine. ( Brown, MJ, 1985)
"Defibrotide is a polydeoxyribonucleotide of mammalian origin which possesses profibrinolytic effect and PGI2-releasing capacity."1.27Beneficial effects of defibrotide against myocardial ischemia and decline of beta-adrenoceptor function in the rabbit. ( Berti, F; Mandelli, C; Niada, R; Omini, C; Pretolani, M; Rossoni, G, 1986)
"The alprazolam treated group had a significantly smaller proportion of infarcted tissue in the ventricular section (2."1.27Alprazolam decreases isoproterenol induced myocardial damage in the rat. ( Berkowitz, K; Conahan, S; Vogel, WH, 1988)
"Isoproterenol (ISO) was injected in 5 mg/kg i."1.27Cardioprotective effect of prostacyclin and 7-oxo-PGI2 in rats against chronic isoproterenol damage. ( Körmöczy, PS; Kovács, G; Mikus, E; Tardos, L; Vértesi, C, 1987)
"5 mg) given intracoronary, a dose that shifted the isoproterenol dose-response curve to the right, slowed ventricular tachycardia from 174 +/- 7."1.27Autonomic control of ventricular tachycardia: direct effects of beta-adrenergic blockade in 24 hour old canine myocardial infarction. ( Constantin, L; Martins, JB, 1987)
" Three days post-AMI the dose-response curve for isoproterenol of right ventricular dP/dtmax was significantly depressed, while the inotropic effect of histamine was not impaired."1.26Impaired beta-adrenergic stimulation in the uninvolved ventricle post-acute myocardial infarction: reversible defect due to excessive circulating catecholamine-induced decline in number and affinity of beta-receptors. ( Baumann, G; Blömer, H; Blümel, G; Erhardt, WD; Felix, SB; Ludwig, L; Riess, G, 1981)
"Pretreatment with sulfinpyrazone reduced isoproterenol-induced lesions by 42%."1.26Reduction in the severity of myocardial infarction by sulfinpyrazone. ( Innes, IR; Weisman, H, 1981)
"Experimental myocardial infarction has been induced in rats by isoprenaline pretreatment and progress of the lesions has been observed histologically at intervals over a period of 6 weeks."1.26Abnormal electrocardiographic activity revealed by isolated rat heart preparations at various times after experimental myocardial infarction. ( Hicks, R; Sahyoun, HA, 1981)
" Particularly with the primarily cardioselective beta-stimulating agent dobutamine a marked positive inotropic effect can be achieved in a range of dosage not significantly affecting heart rate and peripheral resistance."1.26[Catecholamines for treatment of severe heart failure (author's transl)]. ( Kübler, W; Mäurer, W; Tillmanns, H, 1979)
"The latter group of arrhythmias was characterized by sinus arrest or severe sinus bradycardia (90%) and complete A-V block (10%)."1.26Prehospital brady-asystolic cardiac arrest. ( Humphrey, SB; Iseri, LT; Siner, EJ, 1978)
"Massive myocardial infarction was then induced in intact and CCL4-treated animals."1.26Effect of CCL4-induced cirrhosis on the pathophysiologic course of acute myocardial infarction in nonarteriosclerotic vs arteriosclerotic male rats. ( Greenberg, BP; Wexler, BC, 1979)
"The necrosis was confirmed by ECG changes, increased serum activities of AspAT, AlAT, GPT and LDH, and by histological examination."1.26A temporal profile of changes in myocardial manganese after isoprenaline induced cardiac necrosis in albino rats. ( Ahmad, M; Hasan, MZ; Jameel, SA; Kumar, S; Mathew, BM; Seth, TD, 1979)
"The greater sensitivity of phase 1a arrhythmias to beta-blockade and the lack of a decrease in ventricular fibrillation threshold during phase 1b might indicate differences in the genesis of arrhythmias and fibrillation in phases 1a and 1b."1.26Prophylaxis of ventricular fibrillation after acute experimental coronary occlusion by chronic beta-adrenoceptor blockade with atenolol. ( Bucher, P; Meesmann, W; Menken, U; Wiegand, V, 1979)
"Isoprenaline dosed 50 mg/kg was injected intraperitoneally into rats aged 42 days, 3 months, and 18 months."1.26Age-dependent variations in the intensity of isoprenaline-induced myocardial lesions in rats. ( Kalincák, M; Kohút, A; Machán, V; Nicák, A; Vilcek, S, 1978)
"Pretreatment with verapamil 25 mg/Kg s."1.26Effect of verapamil on the transmural energy metabolism in the isoproterenol-induced myocardial lesion. ( Higuchi, M; Takenaka, F, 1978)
"Myocardial infarction was produced by subcutaneous injection of isoproterenol, 85 mg/kg body weight, on 2 consecutive days."1.25Effect of conditioning on myocardial metabolism after myocardial infarction. ( Ahmad, M; Tajuddin, M; Tariq, M, 1975)
" The dose-response curve of TM was parallel to that of nitroglycerin and papaverine and steeper than that of dipyridamol or adenosine."1.25[Pharmacology of cornary dilator agent, trapymin. (2) Analysis of its mode of action]. ( Ogawa, N; Ohnishi, H; Tsukuda, S; Yamaguchi, K, 1975)
"Myocardial infarction was produced by occlusion of the left anterior descending coronary artery in open-chest dogs."1.25Effect of inhibition of lipolysis on infarct size after experimental coronary artery occlusion. ( Kjekshus, JK; Mjos, OD, 1973)
"Clinical signs of congestive heart failure significantly correlated with a fall in FEV and FEF(25-75%), the development of frequency dependence of R(T), and elevation of the pulmonary wedge pressure."1.25Interrelation between alterations in pulmonary mechanics and hemodynamics in acute myocardial infarction. ( Hodges, M; Hyde, RW; Interiano, B; Yu, PN, 1973)

Research

Studies (1,089)

TimeframeStudies, this research(%)All Research%
pre-1990456 (41.87)18.7374
1990's76 (6.98)18.2507
2000's170 (15.61)29.6817
2010's274 (25.16)24.3611
2020's113 (10.38)2.80

Authors

AuthorsStudies
Abukhalil, MH1
Hussein, OE1
Aladaileh, SH1
Althunibat, OY1
Al-Amarat, W1
Saghir, SA1
Alfwuaires, MA1
Algefare, AI1
Alanazi, KM1
Al-Swailmi, FK1
Kamel, EM1
Mahmoud, AM1
Asdaq, SMB1
Alamri, AS1
Alsanie, WF1
Alhomrani, M1
Emran, T1
Chowdhury, NI1
Sarker, M1
Bepari, AK1
Hossain, M1
Rahman, GMS2
Reza, HM3
Demir, M1
Altinoz, E1
Elbe, H1
Bicer, Y1
Yigitturk, G1
Karayakali, M1
Ballur, AFH1
Liu, C1
Li, B2
Yan, Q1
Niu, S1
Zhao, Y3
Xiong, C1
Zhang, T2
Wei, J2
Cinar, I2
Yayla, M1
Tavaci, T1
Toktay, E1
Ugan, RA1
Bayram, P1
Halici, H1
Oglakci-Ilhan, A1
Kusat-Ol, K1
Uzuner, K2
Uysal, O1
Sogut, I1
Yucel, F1
Kanbak, G2
El-Shaer, NO1
El Gazzar, WB1
Allam, MM2
Anwer, HM1
Hosseinabadi, M1
Abdolmaleki, Z1
Beheshtiha, SHS1
Paulino, ET2
Rodrigues, AKBF1
Machado, MLDP1
de Oliveira, KRV1
Bernardino, AC1
Quintans-Júnior, LJ1
Oliveira, AP1
Ribeiro, ÊAN1
Medhet, M1
El-Bakly, WM1
Badr, AM1
Awad, A1
El-Demerdash, E2
Munir, I1
Hassan Mehmood, M1
Faisal, N1
Hanif, M1
Naseer, D1
Al-Botaty, BM1
Elkhoely, A1
K El-Sayed, E1
Ahmed, AAE1
Spasov, AA1
Kucheryavenko, AF1
Khaliullin, FA1
Gurova, NA1
Sirotenko, VS1
Samorodov, AV1
Gaidukova, KA1
Pavlov, VN1
Gonçalves, MSS1
Silva, EAP1
Santos, DM1
Santana, IR1
Souza, DS3
Araujo, AM1
Heimfarth, L1
Vasconcelos, CML2
Santos, VCO2
Santos, MRV2
de S S Barreto, R1
Quintans Júnior, LJ1
Barreto, AS1
Thomas, J2
Anderson, T1
James-Green, T1
Nwokocha, M2
Palacios, J2
Pepple, D1
Nwokocha, C2
Ramakrishna, K1
Krishnamurthy, S1
Wahid, M2
Saqib, F3
Chicea, L1
Ahmedah, HT2
Sajer, BH1
Marc Vlaic, RA2
Pop, OL2
Moga, M3
Gavris, C1
Hosseini, A1
Rajabian, A1
Sobhanifar, MA1
Alavi, MS1
Taghipour, Z1
Hasanpour, M1
Iranshahi, M1
Boroumand-Noughabi, S1
Banach, M1
Sahebkar, A1
Ponnian, SMP4
Al-Huqail, AA1
Bigiu, N1
Irimie, M1
Chicea, LM1
Younis, NS5
Mohamed, ME5
Shervin Prince, S1
Stanely Mainzen Prince, P23
Berlin Grace, VM1
Khalifa, AA2
El Sokkary, NH1
Elblehi, SS1
Diab, MA1
Ali, MA1
Zou, G1
Wan, J1
Balupillai, A1
David, E1
Ranganathan, B1
Saravanan, K1
Tóth, K2
Oroszi, T1
van der Zee, EA1
Nyakas, C1
Schoemaker, RG3
Ghazouani, L4
Khdhiri, E4
Elmufti, A3
Zarei, A1
Feriani, A5
Baaziz, I2
Hajji, R8
Abid, M2
Ammar, H4
Abid, S4
Allouche, N7
Mnafgui, K10
Ramazani, A1
Tlili, N3
Tir, M3
Aldahmash, W1
Hichem, A1
Gómez-Caravaca, AM1
Del Mar Contreras, M1
Taamalli, A1
Alwasel, S1
Segura-Carretero, A1
Harrath, AH1
Yin, Y1
Wang, L4
Chen, G1
You, H2
Rathod, S1
Agrawal, Y1
Sherikar, A1
Nakhate, KT1
Patil, CR4
Nagoor Meeran, MF8
Ojha, S9
Goyal, SN7
Yang, Y2
Han, J1
Lilly, RG1
Yang, Q3
Guo, Y2
Rhana, P2
Barros, GM1
Costa, AD1
Santos, DMD1
Fernandes-Braga, W1
Durço, AO1
Roman-Campos, D2
Cruz, JS2
Verma, H1
Bhattacharjee, A1
Shivavedi, N1
Nayak, PK1
Deger, N1
Ozmen, R1
Karabulut, D1
Yovas, A3
Manjusha, WA1
Akhtar, MS6
Hassan, Q1
Afzal, O1
Altamimi, A1
Hassan, MZ1
Sharma, AK4
Mohammad, AAS1
Tabassum, F1
Zhang, M3
Chen, J1
Wang, Y5
Kang, G1
Zhang, Y8
Han, X1
Rong, N1
Yang, R1
Ibrahim, IAA1
Zhang, W4
Li, L1
Ma, H1
Jiang, H2
Xia, B1
Sberi, HA1
Elhefny, MA1
Lokman, MS1
Kassab, RB1
Beyazcicek, E1
Beyazcicek, O1
Moreno, KGT1
de Almeida, TL1
Marques, AAM1
Donadel, G1
Lourenço, ELB1
de Almeida, DAT1
Gasparotto, A1
Elseweidy, MM1
Ali, SI1
Shaheen, MA1
Abdelghafour, AM1
Hammad, SK1
Hassan, GM1
Ebrahim, RH1
Liao, J1
Ma, C2
Wu, G1
Yaseen, MS1
Mohammed Ali, N1
Stanely, SP2
Aodah, AH1
Devi, S2
Alkholifi, FK1
Yusufoglu, HS1
Foudah, AI1
Alam, A1
Wang, H2
Xie, B1
Shi, S1
Zhang, R2
Liang, Q2
Liu, Z1
Cheng, Y2
Mi, X1
Zhang, Z1
Cheng, J2
Xu, Z2
Zhu, K1
Ren, Y1
Holanda, TM1
Rocha, DG1
Silveira, JAM1
Costa, PPC1
Maia, PHF1
Ingram, C1
Moraes, MEA1
Fechine, FV1
Moraes Filho, MO1
Zhang, X4
Zhao, X2
Zhang, J5
Diao, J1
Jia, S1
Feng, P1
Yu, P1
Cheng, G1
Jghef, MM1
Boukholda, K1
Chtourou, Y1
Fiebich, BL1
Kebieche, M1
Soulimani, R1
Chigr, F1
Fetoui, H1
Issac, R1
Ben Mansour, H1
Barchukov, VV1
Tsorin, IB1
Likhosherstov, AM1
Vititnova, MB1
Mokrov, GV1
Gudasheva, TA1
Kryzhanovskii, SA1
Panda, V2
Bhandare, N1
Mistry, K1
S, S1
Dande, P1
Qu, C1
Xu, DQ1
Yue, SJ1
Shen, LF1
Zhou, GS1
Chen, YY1
Wang, XP1
Bai, JQ1
Liu, F1
Tang, YP1
Zhao, BC1
Duan, JA1
Zhang, JC1
Xia, L1
Jiang, Y2
Wu, DQ1
Liu, SC1
Zhou, XN1
Zhang, FX1
Bei, W1
Jing, L2
Chen, N1
Cai, Y1
Li, Y6
Dang, M1
Lin, X1
Sun, L2
Hu, Y2
Mishra, A1
Sreeharsha, N1
Moktan, JB1
Kumar, P1
Sultan, F1
Kaur, R1
Mir, AH1
Maqbool, I1
Lonare, M1
Singh, D1
Rampal, S1
Dar, JA1
Govindasami, S1
Uddandrao, VVS1
Raveendran, N1
Sasikumar, V1
Alabi, B1
Omobowale, T1
Badejo, J1
Adedapo, A1
Fagbemi, O1
Iwalewa, O1
Halici, Z5
Dincer, B1
Sirin, B1
Cadirci, E1
Wang, J4
Wu, X2
Sun, JH1
Yang, HX1
Yao, TT1
Ruan, L1
Xu, GR1
Zhang, C2
Guo, GX1
Li, AY1
Ahmed, LA2
Hassan, OF1
Galal, O1
Mansour, DF1
El-Khatib, A1
Vorkapić, M1
Savić, A1
Janković, M1
Useinović, N1
Isaković, M1
Puškaš, N1
Stanojlović, O1
Hrnčić, D1
Gan, M1
Zhang, S3
Fan, Y2
Tan, Y1
Guo, Z2
Chen, L1
Bai, L1
Jiang, D1
Hao, X1
Li, X5
Shen, L1
Zhu, L1
Khalaf, HM1
Abdalla, AM1
Ahmed, AF1
Abdel-Aziz, AM1
Mujahid, K1
Aslam, MA1
Modhi, A1
Moga, MA1
Bobescu, E1
Marceanu, L1
Zhou, FT1
Ma, K1
Jannesar, K1
Abbaszadeh, S1
Malekinejad, H1
Soraya, H5
Zhang, H2
Chen, H2
Li, J3
Bian, Y1
Song, Y2
Li, Z1
He, F1
Liu, S2
Tsai, Y1
Maccari, S1
Pace, V1
Barbagallo, F1
Stati, T1
Ambrosio, C1
Grò, MC1
Molinari, P1
Vezzi, V1
Catalano, L1
Matarrese, P1
Patrizio, M1
Rizzi, R1
Marano, G1
Zhang, B3
Yang, Z1
Cao, M1
Wang, K2
Wang, G1
Zhang, L2
Xia, Z1
Liu, B2
Cui, L1
Ding, W1
Liu, D1
Dey, P1
Roy, SJ3
Sivasangari, S1
Asaikumar, L1
Vennila, L4
Xu, W1
Li, XP1
Li, EZ1
Liu, YF1
Zhao, J4
Wei, LN1
Ma, L1
Su, X1
Su, G1
Ravindran, S1
Gopalakrishnan, S1
Kurian, GA1
Viswanadha, VP1
Dhivya, V2
Beeraka, NM1
Huang, CY2
Gavryushova, LV1
Minyaeva, NN1
Chubarev, VN1
Mikhaleva, LM1
Tarasov, VV1
Aliev, G1
Karimkhani, H1
Özkoç, M1
Shojaolsadati, P1
Donmez, DB1
Krasina, ME1
Kosheleva, NV1
Lipina, TV1
Karganov, MY1
Medvedeva, YS1
Lebedeva, MA1
Zurina, IM1
Saburina, IN1
Wang, C1
Li, H5
Chen, Y2
Feng, J1
Ali Alharbi, S1
Deng, Y1
Simko, F1
Baka, T1
Repova, K1
Aziriova, S1
Krajcirovicova, K1
Paulis, L1
Adamcova, M1
Tapa, S1
Francis Stuart, SD1
Wang, Z2
Habecker, BA1
Ripplinger, CM1
Thangaiyan, R1
Govindasamy, K1
Forte, E1
Panahi, M1
Baxan, N1
Ng, FS1
Boyle, JJ1
Branca, J1
Bedard, O1
Hasham, MG1
Benson, L1
Harding, SE1
Rosenthal, N1
Sattler, S1
Audigane, L1
Persello, A1
Piriou, N1
Ferron, M1
Trochu, JN1
Lauzier, B1
Gauthier, C1
Rozec, B1
Lu, Y3
Yang, M1
Peng, M1
Xie, L1
Shen, A1
Lin, S1
Huang, B1
Chu, J1
Peng, J1
Huang, J1
Shen, H1
Jiang, M1
Huang, L2
Yuan, Y2
Wang, Q1
Chelluri, LK1
Mohanram, Y1
Jain, R1
Mallarpu, CS1
Ponnana, M1
Kumar, D2
Krishna Venuganti, VV1
Kancherla, R1
Papineni, RV1
Towner, R1
Ghosal, P1
Zaafan, MA2
Abdelhamid, AM2
Ncir, M1
Jallouli, D1
Jamoussi, K1
Meeran, MFN2
Azimullah, S3
Adeghate, E1
Sangeethadevi, G1
V V, SU1
Jansy Isabella, RAR1
Saravanan, G3
Ponmurugan, P2
Chandrasekaran, P1
Sengottuvelu, S1
Vadivukkarasi, S1
Naseroleslami, M1
Aboutaleb, N1
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Ansari, MA2
Baboota, S1
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Todorovic, D1
Mutavdzin, S1
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Bozic Nedeljkovic, B1
Stankovic, S1
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Djuric, D1
Soumya, RS1
Raj, KB1
Abraham, A1
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Garjani, A9
Mousavi, S1
Mohammadi, M2
Vaez, H1
HarishKumar, R1
Selvaraj, CI1
Elasoru, SE1
de Oliveira Barreto, T1
Naves de Souza, DL1
Menezes-Filho, JER1
Loes Moreira, MV1
Gomes Campos, MT1
Adedosu, OT1
Melo, MM1
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Tolba, MF1
Elsherbini, DA1
El-Naga, RN1
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Mangali, S1
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Elhadidy, WF1
Rashad, RM1
Pullaiah, CP1
Nelson, VK1
Rayapu, S1
G V, NK1
Kedam, T1
Abdelmonem, M1
Ibrahim, SM1
Essam, RM1
Amin, HAA1
Abd-Elmawla, MA1
Simirgiotis, MJ1
Young, L1
Thompson, R1
Cifuentes, F1
Paredes, A1
Delgoda, R1
Liu, J3
Sun, M1
Lin, L1
Miao, L1
Ge, Z2
Yang, B2
Mahajan, UB4
Chandrayan, G1
Arya, DS16
Suchal, K2
Agrawal, YO3
Zaki, SM1
Abdalla, IL1
Sadik, AOE1
Mohamed, EA1
Kaooh, S1
Wei, H1
Wan, SP1
Zeng, QT1
Cheng, LX1
Jiang, LL1
Peng, YD1
Alam, MN1
Hossain, MM1
Rahman, MM2
Subhan, N2
Mamun, MAA1
Ulla, A1
Alam, MA2
Althaf Hussain, S1
Kareem, MA3
Rasool, SN3
Al Omar, SY1
Saleh, A1
Al-Fwuaires, MA1
Daddam, JR1
Devi, KL2
Krushna, GS2
Shivaranjani, VL1
Umamaheswari, J1
Srinivasulu, C2
Hussain, SA1
Reddy, VD1
Ali, D1
Lokhande, KB1
Swamy, KV1
Kodidhela, LD2
E, MP1
Mopuri, R1
Pulaganti, M1
Islam, MS1
K R, DG1
Irene, M1
Jia, G1
Zao, M1
Liu, X3
Daoud, A1
Ben Mefteh, F1
Turki, M1
Jmal, S1
Ben Amar, R1
Ayadi, F1
ElFeki, A3
Abid, L1
Rateb, ME1
Belbahri, L1
Kadri, A2
Gharsallah, N5
Tasatargil, A1
Kuscu, N1
Dalaklioglu, S1
Adiguzel, D1
Celik-Ozenci, C1
Ozdem, S2
Barutcigil, A1
Jana, S1
Patel, D1
Patel, S1
Upadhyay, K1
Thadani, J1
Mandal, R1
Das, S2
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Paul, S2
Tanvir, EM4
Hossen, MS1
Saha, M1
Afroz, R4
Islam, MA1
Hossain, MS2
Gan, SH4
Ibrahim Khalil, M1
Sharmila Queenthy, S1
John, B2
Wong, ZW1
Thanikachalam, PV1
Ramamurthy, S1
Sözmen, M2
Devrim, AK2
Kabak, YB2
Devrim, T2
Sudagidan, M2
Nour, MS1
Sarhan, NR1
Mazroa, SA1
Gawish, SA1
Tanriverdi, LH1
Parlakpinar, H1
Ozhan, O1
Ermis, N1
Polat, A1
Vardi, N1
Tanbek, K1
Yildiz, A1
Acet, A1
Khan, V3
Hassan, MQ6
Akhtar, M7
Najmi, AK7
Hemalatha, KL5
Rathinavel, A1
Sankar, J1
Mohammed Sadullah, SS1
Niranjali Devaraj, S4
Kadry, MO1
Abdel-Megeed, RM1
Ivey, MJ1
Kuwabara, JT1
Pai, JT1
Moore, RE1
Sun, Z1
Tallquist, MD1
Cui, XH1
Wang, HL2
Wu, R1
Yao, PA1
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Gao, JP1
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Sharma, S2
Bhandari, U5
Ali, SM1
Haque, SE6
Darwesh, AM1
El-Azab, MF1
Abo-Gresha, NM2
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Moustafa, YM2
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Rungsung, S1
Kumar, T1
Kandasamy, A1
Parida, S1
Lingaraju, MC1
Kumar, A3
Ashokkumar, R1
Jamuna, S1
Sakeena Sadullah, MS1
Houson, HA1
Nkepang, GN1
Hedrick, AF1
Awasthi, V1
Xu, Y4
Wu, L1
Chen, A1
Xu, C2
Feng, Q1
Li, F1
Fan, XX1
Chu, C1
Kou, JP1
Yu, BY2
El Agaty, SM1
Yu, Y1
Jin, L1
Zhuang, Y1
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Guo, K1
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Sun, Q1
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Sakr, HF1
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Khurana, A2
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Khwaja, S1
Mahmood, T1
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Laham, F2
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Jain, PG1
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Ali, SS1
Mohamed, SFA1
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Tariq, S1
Iqbal, R1
Jairajpuri, Z1
Shahzad, S1
Mateen, S1
Mubeena Mariyath, PM1
Naeem, SS1
Akhtar, K1
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Moin, S1
Ibrar, M1
Khan, MA1
Nisar, M1
Khan, M1
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Alada, ARA1
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Morand, P2
Pairolero, PC2
McCallister, BD2
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Titus, JL2
Ellis, FH2
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Gomazkov, OA1
Kones, RJ1
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Carpi, C2
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Nobel, NL1
Mimnaugh, MN1
Counsell, RE1
Kniffen, FJ1
Vaisrub, S1
Dighton, DH1
el-Sherif, N1
Scherlag, BJ1
Lazzara, R1
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Williams, DO1
Samet, P1
Vyden, JK2
Nagasawa, K1
Rabinowitz, B1
Parmley, WW1
Tomoda, H1
Corday, E2
Swan, HJ3
Willen, D1
Mir, MA1
Rees, S1
Yahya, AM1
Williams, JD1
Reeves, TL1
Marshall, RJ2
Parratt, JR2
Most, AS1
Capone, RJ1
Szydlik, P1
Bruno, CA1
DeVona, TS1
Branzi, A1
Binetti, G1
Zannoli, R1
Magnani, B1
Morita, Y1
Ishiyama, T1
Tsukamoto, N1
Yamamura, Y1
Tekeres, M1
Mezey, B1
Kellényi, L1
Asai, Y1
Mueller, H3
Ayres, SM3
Giannelli, S3
Conklin, EF2
Mazzara, JT2
Grace, WJ3
Doshchitsin, VL1
Eremina, GA1
Moran, JM1
Mulet, J1
Caralps, JM1
Pifarre, R1
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Wagner, GS1
Wallace, AG1
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Wiener, L1
Johnson, SA1
Marchal, C1
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Sztuka, JC1
Malingrey, L1
Benichoux, R1
Daoud, FS1
Jacobsen, JR1
Perret, C1
Enrico, JF1
Poli, S1
Amacker, JJ1
Gill, C1
Wechsler, AS1
Lutmer, RJ1
Saroff, J3
Seelig, MS1
Christiansen, I1
Haghfelt, T1
Amtorp, O1
Shell, WE3
Sobel, BE5
Rivier, JL2
Jaeger, M2
Jonas, N1
Interiano, B1
Hyde, RW1
Hodges, M1
Yu, PN1
Bleifeld, W1
Irnich, W1
Lavelle, JF1
Covell, JW4
Chung, EK1
Ledingham, IM1
Ramdohr, B1
Lutmer, RF4
Kaplinsky, E1
Lown, B3
Lekven, J1
Mijös, OD1
Mazzoni, S1
Codreanu, R1
Bramante, PO1
Nirdlinger, EL1
Gagossi, M1
Coppi, G1
Bonardi, G1
Bravi, A1
Volpi, G1
Pupillo, A1
De Luca, FM1
Tuveri, A1
Humphries, JO1
Puri, PS2
Schneider, JA1
Sperelakis, N1
Sapsford, RN1
Blackstone, EH1
Kirklin, JW1
Karp, RB1
Kouchoukos, NT1
Pacifico, AD1
Roe, CR1
Bradley, EL1
Moyer, JH1
Mills, LC1
Stavrakos, C1
Blackford, JM1
Bowers, JD1
Heydinger, DK1
Cranston, WI1
Jacovella, G1
Milazzotto, F1
Masini, V1
Forrester, JS1
Danzig, R3
Allen, HN1
Haddy, FJ1
Camillo, OS1
Lemberg, L1
Castellanos, A1
Arcebal, AG1
Iyengar, RN1
Sloman, G1
Dowling, J1
Vohra, J1
McLean, AP1
Patton, RD1
Körge, K1
Hanson, H1
Hering, L1
Lipso, E1
Maramaa, S1
Velbri, S1
Selve, H1
McCarthy, B2
Jouve, A1
Delaage, M1
Torresani, J1
Nicolai, P1
Heuillet, G1
Pinas, E1
McLean, KH2
Wynn, A1
Marriott, HJ1
Pilny, J1
Kiefer, G1
Sandritter, W1
Abbondati, G1
Foucault, JP1
Nicolas, G1
Bonhour, JB1
Potier, JC1
Guilleman, D1
Godin, JF1
Kobayashi, K1
Ratshin, RA1
Russell, RO1
Kizer, DE2
Howell, BA2
Krasnow, N1
Rohl, D1
Liu, CK1
Lee, JY1
Griminger, P1
Woie, L1
Aksnes, EG1
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Reicher-Reiss, H1
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Heikkilä, J1
Tabakin, BS1
Hugenholtz, PG1
Davis, DL1
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Goetz, RH1
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Richmond, S1
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Meltzer, Y1
Guschwan, A2
Trenckmann, H1
Herbinger, W1
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Fiero, MK1
Novak, J1
Ino, T1
Langley, RB1
Wilson, DF1
Turner, AS1
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Mihail, A1
Popescu, P1
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Bloor, CM1
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Kaya, K1
Hiraiwa, T1
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Kumar, R1
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Nagornev, VA1
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Dhurandhar, RW1
Teasdale, SJ1
Mahon, WA1
Tremblay, GM1
Charland, R1
Roy, P1
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Robelli, F1
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Orr, DS1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Scheme of Primary Prevention of Infection by COVID-19, in Workers: Phase II Controlled Clinical Trial, to be Carried Out in Medellín-Antioquia[NCT04420260]152 participants (Actual)Interventional2021-03-18Completed
Effect of Moringa Oleifera on Bone Density in Post-Menopausal Women[NCT03026660]20 participants (Actual)Interventional2015-07-31Completed
Phase III Study of Metabolic Intervention With Glutamate in Coronary Surgery II[NCT02592824]Phase 3321 participants (Actual)Interventional2015-11-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Mortality

Postoperative mortality was defined as mortality within 30 days of surgery. (NCT02592824)
Timeframe: up to 30 days

InterventionParticipants (Count of Participants)
Intravenous Glutamate Infusion1
Intravenous Saline Infusion6

Incidence of Unexpected Adverse Events

suspected unexpected serious adverse reaction (NCT02592824)
Timeframe: within 24 hours from infusion

InterventionParticipants (Count of Participants)
Intravenous Glutamate Infusion0
Intravenous Saline Infusion0

Number of Participants With Incidence of Stroke

"Postoperative stroke was defined as neurological or cognitive deficit with a cerebral injury verified on (Computed Tomography) CT-scan. All suspected cases of stroke underwent CT-scan.~Stroke within 24 h of surgery was defined as a stroke that occurred within 24 h of surgery or signs of a stroke, when first assessable in deeply sedated patients on a ventilator." (NCT02592824)
Timeframe: within 24 hours from surgery

InterventionParticipants (Count of Participants)
Intravenous Glutamate Infusion0
Intravenous Saline Infusion4

Postoperative Increase of Plasma NT-proBNP

"Postoperative increase of NT-proBNP reflects postoperative myocardial dysfunction sustained in association with surgery. NT-proBNP usually peaks on the third to fourth postoperative day after coronary artery bypass surgery.~In the first GLUTAMICS trial a good agreement between hemodynamic criteria for postoperative heart failure and postoperative NT-proBNP was found." (NCT02592824)
Timeframe: from the day before surgery to the third postoperative day

Interventionng/L (Mean)
Intravenous Glutamate Infusion5390
Intravenous Saline Infusion6452

Postoperative Increase of Plasma NT-proBNP in Patients Without Diabetes

"Postoperative increase of NT-proBNP reflects postoperative myocardial dysfunction sustained in association with surgery. NT-proBNP usually peaks on the third to fourth postoperative day after coronary artery bypass surgery.~Previous observations suggest a blunted effect of glutamate in diabetic hearts." (NCT02592824)
Timeframe: from preoperative level to the third postoperative day

Interventionng/L (Mean)
Intravenous Glutamate Infusion4503
Intravenous Saline Infusion6825

Postoperative Plasma Level of NT-proBNP

Postoperative NT-proBNP reflects postoperative myocardial dysfunction. (NCT02592824)
Timeframe: first postoperative day

Interventionng/L (Mean)
Intravenous Glutamate Infusion4438
Intravenous Saline Infusion4420

Postoperative Plasma Level of NT-proBNP

Postoperative NT-proBNP reflects postoperative myocardial dysfunction. (NCT02592824)
Timeframe: third postoperative day

Interventionng/L (Mean)
Intravenous Glutamate Infusion8055
Intravenous Saline Infusion8804

Reviews

49 reviews available for isoproterenol and Cardiovascular Stroke

ArticleYear
Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 94

    Topics: Animals; Biological Products; Humans; Isoproterenol; Lipid Peroxidation; Myocardial Infarction; Oxid

2017
Isoproterenol-induced cardiac ischemia and fibrosis: Plant-based approaches for intervention.
    Phytotherapy research : PTR, 2018, Volume: 32, Issue:10

    Topics: Alkaloids; Animals; Fibrosis; Flavonoids; Glycosides; Heart; Humans; Isoproterenol; Myocardial Infar

2018
EXPERIMENTAL CARDIAC NECROSIS.
    Biochemical clinics, 1963, Volume: 2

    Topics: Chlorides; Desoxycorticosterone; Dihydrotachysterol; Heart; Humans; Hypokalemia; Isoproterenol; Magn

1963
STUDIES ON INFARCT-LIKE MYOCARDIAL NECROSIS PRODUCED BY ISOPROTERENOL: A REVIEW.
    Revue canadienne de biologie, 1963, Volume: 22

    Topics: Desoxycorticosterone; Dogs; Epinephrine; Heart Diseases; Hyperthyroidism; Hypokalemia; Isoproterenol

1963
The role of diuretics and inotropic therapy in failure associated with myocardial infarction.
    Archives internationales de physiologie et de biochimie, 1984, Volume: 92, Issue:4

    Topics: Acute Disease; Blood Pressure; Cardiac Complexes, Premature; Cardiotonic Agents; Chronic Disease; Di

1984
Acute myocardial infarction--coronary thrombosis and salvage of the ischemic myocardium.
    Cardiovascular clinics, 1983, Volume: 14, Issue:1

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Collateral Circulation; Coronary Circulation;

1983
Pharmacologic support in cardiogenic shock.
    Advances in shock research, 1983, Volume: 10

    Topics: Animals; Cardiotonic Agents; Diagnosis, Differential; Digitalis Glycosides; Diuretics; Dobutamine; D

1983
Parasympathetic effects on electrophysiologic properties of cardiac ventricular tissue.
    Journal of the American College of Cardiology, 1983, Volume: 2, Issue:6

    Topics: Acetylcholine; Action Potentials; Animals; Arrhythmias, Cardiac; Atropine; Catecholamines; Cats; Dig

1983
Inotropic agents in the treatment of cardiogenic shock.
    Pharmacology & therapeutics, 1983, Volume: 22, Issue:1

    Topics: Cardiac Output, Low; Cardiac Tamponade; Cardiotonic Agents; Catecholamines; Digitalis; Dobutamine; D

1983
Right precordial coved ST-T segment elevation in a healthy subject evaluated by isoproterenol infusion test. A case report.
    Angiology, 1994, Volume: 45, Issue:5

    Topics: Aged; Chest Pain; Diagnosis, Differential; Electrocardiography; Female; Humans; Isoproterenol; Myoca

1994
Clinical usefulness of the beta-adrenergic antagonists.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Jul-22, Volume: 54, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Anx

1978
Influence of environmental stress on pathogenesis of sudden cardiac death.
    Federation proceedings, 1977, Volume: 36, Issue:5

    Topics: Adenosine Triphosphate; Animals; Catecholamines; Coronary Circulation; Coronary Disease; Death, Sudd

1977
Myocardial ischemia (second of three parts).
    The New England journal of medicine, 1977, May-05, Volume: 296, Issue:18

    Topics: Acute Disease; Animals; Coronary Disease; Creatine Kinase; Dogs; Fatty Acids; Fatty Acids, Nonesteri

1977
[Experimental models for the pharmacologic study of anti-arrhythmia drugs].
    Acta cardiologica, 1977, Volume: Suppl 22

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Aprindine; Coronary Vessels; Dogs; Drug Evaluation, Prec

1977
Use of catecholamines in acute myocardial infarction.
    Herz, 1979, Volume: 4, Issue:5

    Topics: Animals; Blood Volume; Catecholamines; Dobutamine; Dogs; Dopamine; Epinephrine; Hemodynamics; Humans

1979
Effects of metabolic and pharmacologic interventions on myocardial infarct size following coronary occlusion.
    Circulation, 1976, Volume: 53, Issue:3 Suppl

    Topics: Anaerobiosis; Animals; Dogs; Humans; Hyaluronoglucosaminidase; Hydrocortisone; Insulin; Isoprotereno

1976
Current concepts on mechanisms and treatment of cardiogenic shock.
    American heart journal, 1976, Volume: 92, Issue:1

    Topics: Adrenal Cortex Hormones; Aged; Blood Pressure Determination; Cardiac Output; Coronary Vessels; Digit

1976
Dynamics of n-3 and n-6 fatty acids in phospholipids of heart muscle.
    Journal of internal medicine. Supplement, 1989, Volume: 731

    Topics: Aging; Animals; Animals, Newborn; Catecholamines; Death, Sudden; Dietary Fats; Fatty Acids, Unsatura

1989
Effects of magnesium deficiency on the pathogenesis of myocardial infarction.
    Magnesium, 1986, Volume: 5, Issue:3-4

    Topics: Action Potentials; Animals; Arteritis; Calcium; Cardiomyopathies; Cricetinae; Dogs; Electrolytes; Is

1986
Early abnormalities in myocardial cell function in experimental diabetes.
    Acta pharmacologica et toxicologica, 1986, Volume: 59 Suppl 2

    Topics: Adenosine Triphosphate; Adult; Animals; Blood Glucose; Calcium; Calcium-Transporting ATPases; Catech

1986
Magnesium deficiency cardiomyopathy.
    The American journal of cardiovascular pathology, 1988, Volume: 2, Issue:1

    Topics: Animals; Cardiomyopathies; Coronary Vessels; Humans; Isoproterenol; Magnesium Deficiency; Myocardial

1988
Practical considerations in the management of shock complicating acute myocardial infarction. A summary of current practice.
    The American journal of cardiology, 1970, Volume: 26, Issue:6

    Topics: Acute Disease; Arrhythmias, Cardiac; Atropine; Blood Pressure Determination; Central Venous Pressure

1970
[Treatment of arrhythmia at coronary care units].
    Nihon rinsho. Japanese journal of clinical medicine, 1974, Volume: 32, Issue:9

    Topics: Adult; Aged; Ajmaline; Animals; Arrhythmias, Cardiac; Atropine; Bretylium Compounds; Cardiac Complex

1974
The failing myocardium. I. Drug management.
    The Medical clinics of North America, 1973, Volume: 57, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Atropine; Blood Pressure; Blood Volume; Cardiac Output; D

1973
Beta adrenergic blocking drugs in the treatment of cardiac arrhythmias.
    Cardiovascular clinics, 1970, Volume: 2, Issue:2

    Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillatio

1970
The pathophysiologic vulnerability of the subendocardium of the left ventricle.
    Advances in cardiology, 1973, Volume: 9

    Topics: Arrhythmias, Cardiac; Capillaries; Cardiomegaly; Coronary Disease; Coronary Vessels; Endocardium; He

1973
[Role of the sympathetic factor in the pathogenesis of myocardial infarct and isoproterenol necrosis].
    Kardiologiia, 1971, Volume: 11, Issue:9

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Catecholamines; Cyclic AMP; Humans; Isoproterenol;

1971
Cardiogenic shock. Recent advances in pharmacologic management. II.
    New York state journal of medicine, 1973, Aug-01, Volume: 73, Issue:15

    Topics: Adenylyl Cyclases; Adrenal Cortex Hormones; Catecholamines; Cyclic AMP; Depression, Chemical; Digita

1973
[Adrenergic alpha and beta receptors and their specific inhibitors].
    Klinische Wochenschrift, 1968, Feb-01, Volume: 46, Issue:3

    Topics: Action Potentials; Angina Pectoris; Arrhythmias, Cardiac; Blood Circulation; Cardiomyopathy, Hypertr

1968
Bradyarrhythmias in acute myocardial infarction.
    Circulation, 1972, Volume: 45, Issue:3

    Topics: Atropine; Bradycardia; Coronary Circulation; Coronary Vessels; Heart Block; Heart Conduction System;

1972
Myocardial infarction complicated by conduction defect.
    The Medical clinics of North America, 1973, Volume: 57, Issue:1

    Topics: Atropine; Coronary Circulation; Electrocardiography; Heart Block; Heart Conduction System; Heart Rat

1973
[Shock and MDF].
    Kokyu to junkan. Respiration & circulation, 1972, Volume: 20, Issue:5

    Topics: Aged; Animals; Arrhythmias, Cardiac; Cats; Dogs; Electrocardiography; Female; Glucagon; Heart; Human

1972
New developments and therapeutic applications of cardiac stimulating agents.
    The American journal of cardiology, 1973, Sep-20, Volume: 32, Issue:4

    Topics: Cardiac Output; Catecholamines; Digitalis Glycosides; Digitoxin; Digoxin; Dopamine; Glucagon; Heart;

1973
Reduction of infarct size following coronary occlusion.
    Circulation research, 1974, Volume: 35 Suppl 3

    Topics: Anaerobiosis; Animals; Assisted Circulation; Coronary Vessels; Creatine Kinase; Electrocardiography;

1974
Rational therapeutic approach to cardiogenic shock.
    Cardiovascular clinics, 1974, Volume: 6, Issue:2

    Topics: Anticoagulants; Blood Gas Analysis; Blood Volume; Cardiac Catheterization; Dopamine; Electrocardiogr

1974
Cardiogenic shock.
    Triangle; the Sandoz journal of medical science, 1974, Volume: 13, Issue:3

    Topics: Arrhythmias, Cardiac; Assisted Circulation; Central Venous Pressure; Dopamine; Emergencies; Hemodyna

1974
The physiologic basis for treatment of shock associated with myocardial infarction.
    The Medical clinics of North America, 1967, Volume: 51, Issue:1

    Topics: Aged; Blood Pressure; Cardiac Output; Dextrans; Female; Hemodynamics; Humans; Hypotension; Isoproter

1967
A review of current concepts and research in shock.
    The Ohio State medical journal, 1968, Volume: 64, Issue:6

    Topics: Blood Transfusion; Extracellular Space; Homeostasis; Humans; Hypoxia; Isoproterenol; Mephentermine;

1968
Advances in medicine.
    The Practitioner, 1968, Volume: 201, Issue:204

    Topics: Acute Kidney Injury; Asthma; Blindness; Catecholamines; Contraceptives, Oral; Coronary Disease; Guan

1968
[Modern trends in physiopathology and therapy of shock caused by myocardial infarct].
    La Clinica terapeutica, 1969, Jul-31, Volume: 50, Issue:2

    Topics: Adrenal Cortex Hormones; Digitalis Glycosides; Glucagon; Humans; Isoproterenol; Myocardial Infarctio

1969
Power failure in acute myocardial infarction.
    Progress in cardiovascular diseases, 1970, Volume: 12, Issue:6

    Topics: Angiocardiography; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Assisted Circulation; Blood Pressur

1970
Pathophysiology and therapy of the shock of myocardial infarction.
    Annals of internal medicine, 1970, Volume: 73, Issue:5

    Topics: Acute Disease; Animals; Coronary Vessels; Digitalis Glycosides; Dilatation; Disease Models, Animal;

1970
The treatment of arrhythmias following acute myocardial infarction.
    The Medical clinics of North America, 1971, Volume: 55, Issue:2

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atropine; Bradycardia; Coronary Care Units; Digitalis Gly

1971
Prevention and treatment of ventricular dysrhythmias.
    British heart journal, 1971, Volume: 33

    Topics: Arrhythmias, Cardiac; Atropine; Coronary Care Units; Electric Countershock; Heart Block; Humans; Iso

1971
The patient in shock. I.
    Canadian Medical Association journal, 1971, Jul-10, Volume: 105, Issue:1

    Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Arrhythmias, Cardiac; Arteries; Blood Pressure; Cal

1971
Management of arrhythmias in acute myocardial infarction.
    American family physician, 1971, Volume: 4, Issue:1

    Topics: Acid-Base Equilibrium; Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac O

1971
Shock in myocardial infarction--medical treatment.
    The American journal of cardiology, 1970, Volume: 26, Issue:6

    Topics: Animals; Blood Pressure; Coronary Vessels; Digitalis Glycosides; Dogs; Dopamine; Glucagon; Glucose;

1970
The pluricausal cardiopathies.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Antimalarials; Calcinosis; Cardiac Glycosides; Deficiency Diseases;

1969
Management of cardiac dysrhythmias complicating acute myocardial infarction.
    Geriatrics, 1968, Volume: 23, Issue:9

    Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atropine; Bradycardia; Bretylium Compound

1968

Trials

7 trials available for isoproterenol and Cardiovascular Stroke

ArticleYear
[Prevention of sudden death in myocardial infarct: do experimental results help to understand the clinical reality? The case of the clinical trial SWORD (Survival With ORal D-sotalol)].
    Cardiologia (Rome, Italy), 1996, Volume: 41, Issue:8

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Drug Therapy, Combination; Femal

1996
The effect of antilipolytic agents on cyclic AMP, free fatty acid and total catecholamine concentrations in plasma.
    Acta medica Scandinavica, 1976, Volume: 199, Issue:5

    Topics: Acute Disease; Animals; Catecholamines; Clinical Trials as Topic; Cyclic AMP; Dogs; Fatty Acids, Non

1976
[Determination of myocardial contractility using ultrasonic echography].
    La Nouvelle presse medicale, 1975, Apr-12, Volume: 4, Issue:15

    Topics: Cardiac Output; Clinical Trials as Topic; Coronary Disease; Echocardiography; Heart Function Tests;

1975
Letter: F.F.A., lipolysis, and myocardial infarction.
    Lancet (London, England), 1974, Apr-27, Volume: 1, Issue:7861

    Topics: Animals; Clinical Trials as Topic; Dogs; Fatty Acids, Nonesterified; Heart; Humans; Hypolipidemic Ag

1974
Use of drugs in cardiogenic shock due to acute myocardial infarction.
    Circulation, 1972, Volume: 45, Issue:5

    Topics: Acute Disease; Blood Pressure; Central Venous Pressure; Chlorpromazine; Clinical Trials as Topic; De

1972
Coronary perfusion versus cold ischemic arrest during aortic valve surgery. A randomized study.
    Circulation, 1974, Volume: 49, Issue:6

    Topics: Adult; Aged; Aortic Valve; Arrhythmias, Cardiac; Cardiac Catheterization; Cardiac Output; Creatine K

1974
Effect of drugs on myocardial contractility in the intact dog and in experimental myocardial infarction.
    The American journal of cardiology, 1968, Volume: 21, Issue:6

    Topics: Animals; Clinical Trials as Topic; Dogs; Heart; Isoproterenol; Metaraminol; Methoxamine; Muscle Cont

1968

Other Studies

1033 other studies available for isoproterenol and Cardiovascular Stroke

ArticleYear
Visnagin prevents isoproterenol-induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Inflammation; Isoproterenol; Khellin; Male; Myocardial Infarction

2021
Cardioprotective Potential of Garlic Oil and Its Active Constituent, Diallyl Disulphide, in Presence of Carvedilol during Chronic Isoprenaline Injection-Mediated Myocardial Necrosis in Rats.
    Molecules (Basel, Switzerland), 2021, Aug-25, Volume: 26, Issue:17

    Topics: Allyl Compounds; Animals; Antioxidants; Cardiotonic Agents; Carvedilol; Catalase; Disease Models, An

2021
L-carnitine protects cardiac damage by reducing oxidative stress and inflammatory response via inhibition of tumor necrosis factor-alpha and interleukin-1beta against isoproterenol-induced myocardial infarction.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 143

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carnitine; Disease Models, Animal; Fibrosis; Inflam

2021
Effects of pinealectomy and crocin treatment on rats with isoproterenol-induced myocardial infarction.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotonic Agents; Carotenoids; Catalase; Glutathi

2022
Protective Effects and Mechanisms of Recombinant Human Glutathione Peroxidase 4 on Isoproterenol-Induced Myocardial Ischemia Injury.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Animals; Apoptosis; Biomarkers; Cell Line; Disease Models, Animal; Electrocardiography; Humans; Isop

2021
In Vivo and In Vitro Cardioprotective Effect of Gossypin Against Isoproterenol-Induced Myocardial Infarction Injury.
    Cardiovascular toxicology, 2022, Volume: 22, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cardiotox

2022
Effect of chronic alcohol consumption on myocardial apoptosis in the rat model of isoproterenol-induced myocardial injury and investigation on the cardioprotective role of calpain inhibitor 1.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:6

    Topics: Alcohol Drinking; Alcoholism; Animals; Apoptosis; Calpain; Cardiolipins; Caspase 3; Cytochromes c; D

2022
Ghrelin ameliorated inflammation and oxidative stress in isoproterenol induced myocardial infarction through the endothelial nitric oxide synthase (eNOS)/nuclear factor erythroid 2-related factor-2 (NRF2)/heme oxygenase-1 (HO-1) signaling pathway.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2021, Volume: 72, Issue:2

    Topics: Animals; Ghrelin; Heme Oxygenase-1; Inflammation; Isoproterenol; Myocardial Infarction; Myocytes, Ca

2021
Cardiac aorta-derived extracellular matrix scaffold enhances critical mediators of angiogenesis in isoproterenol-induced myocardial infarction mice.
    Journal of materials science. Materials in medicine, 2021, Oct-26, Volume: 32, Issue:11

    Topics: Animals; Aorta; Cell Survival; Extracellular Matrix; Isoproterenol; Male; Malondialdehyde; Mice; Mus

2021
Alpha-terpineol prevents myocardial damage against isoproterenol-MI induced in Wistar-Kyoto rats: new possible to promote cardiovascular integrity.
    Life sciences, 2022, Feb-01, Volume: 290

    Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Cardiotoxicity; Cardiovascular Diseases; Cycl

2022
Thymoquinone attenuates isoproterenol-induced myocardial infarction by inhibiting cytochrome C and matrix metalloproteinase-9 expression.
    Clinical and experimental pharmacology & physiology, 2022, Volume: 49, Issue:3

    Topics: Animals; Apoptosis; Benzoquinones; Biomarkers; Cytochromes c; Gene Expression Regulation, Enzymologi

2022
Pharmacological evaluation of Vitis vinifera and Zingiber zerumbet on electrocardiographic, biochemical alterations and antioxidant status in isoproterenol-induced myocardial infarction in rats.
    Pakistan journal of pharmaceutical sciences, 2021, Volume: 34, Issue:5(Suppleme

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Blood Cell Count; Blood Pressure; Cardiotonic Agent

2021
Ethyl pyruvate attenuates isoproterenol-induced myocardial infarction in rats: Insight to TNF-α-mediated apoptotic and necroptotic signaling interplay.
    International immunopharmacology, 2022, Volume: 103

    Topics: Animals; Isoproterenol; Myocardial Infarction; Myocardium; Oxidative Stress; Pyruvates; Rats; Tumor

2022
Antithrombotic Activity of the Antiplatelet Agent Angipur on the Model of Arterial Thrombosis in Rats with Isoproterenol-Induced Myocardial Infarction.
    Bulletin of experimental biology and medicine, 2022, Volume: 172, Issue:3

    Topics: Animals; Fibrinolytic Agents; Isoproterenol; Myocardial Infarction; Platelet Aggregation Inhibitors;

2022
Nerolidol attenuates isoproterenol-induced acute myocardial infarction in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2022, Volume: 395, Issue:3

    Topics: Animals; Antioxidants; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug;

2022
    Cardiovascular & hematological agents in medicinal chemistry, 2022, Volume: 20, Issue:3

    Topics: Animals; Artocarpus; Hemoglobins; Isoproterenol; Male; Myocardial Infarction; Oxygen; Plant Extracts

2022
Indole-3-carbinol ameliorated the isoproterenol-induced myocardial infarction via multimodal mechanisms in Wistar rats.
    Natural product research, 2022, Volume: 36, Issue:23

    Topics: Animals; Indoles; Isoproterenol; Myocardial Infarction; Rats; Rats, Wistar

2022
Metabolomics analysis delineates the therapeutic effects of hydroethanolic extract of Cucumis sativus L. seeds on hypertension and isoproterenol-induced myocardial infarction.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 148

    Topics: Animals; Cucumis sativus; Hypertension; Isoproterenol; Metabolomics; Myocardial Infarction; Myocardi

2022
Attenuation of isoprenaline-induced myocardial infarction by Rheum turkestanicum.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 148

    Topics: Animals; Creatine Kinase; Dose-Response Relationship, Drug; Isoproterenol; L-Lactate Dehydrogenase;

2022
Preventive effects of (-) epicatechin on tachycardia, cardiac hypertrophy, and nuclear factor- κB inflammatory signaling pathway in isoproterenol-induced myocardial infarcted rats.
    European journal of pharmacology, 2022, Jun-05, Volume: 924

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Cardiomegaly; Catechin; Isoproterenol;

2022
Metabolomics based mechanistic insights to vasorelaxant and cardioprotective effect of ethanolic extract of Citrullus lanatus (Thunb.) Matsum. & Nakai. seeds in isoproterenol induced myocardial infraction.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 100

    Topics: Animals; Cardiomegaly; Chromatography, Liquid; Citrullus; Ethanol; Humans; Isoproterenol; Metabolomi

2022
Anethole's effects against myocardial infarction: The role of TLR4/NFκB and Nrf2/HO1 pathways.
    Chemico-biological interactions, 2022, Jun-01, Volume: 360

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Antioxidants; Apoptosis; Heme Oxygenase-1; Inflammation

2022
Valencene post-treatment exhibits cardioprotection via inhibiting cardiac hypertrophy, oxidative stress, nuclear factor- κB inflammatory pathway, and myocardial infarct size in isoproterenol-induced myocardial infarcted rats; A molecular study.
    European journal of pharmacology, 2022, Jul-15, Volume: 927

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Body Weight; Cardiomegaly; Inflammation

2022
Potential cardioprotective effect of octreotide via NOXs mitigation, mitochondrial biogenesis and MAPK/Erk1/2/STAT3/NF-kβ pathway attenuation in isoproterenol-induced myocardial infarction in rats.
    European journal of pharmacology, 2022, Jun-15, Volume: 925

    Topics: Animals; Biomarkers; Isoproterenol; Myocardial Infarction; Myocardium; Octreotide; Organelle Biogene

2022
Geraniol enhances peroxiredoxin-1, and prevents isoproterenol-induced oxidative stress and inflammation associated with myocardial infarction in experimental animal models.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:8

    Topics: Acyclic Monoterpenes; Animals; Antioxidants; Inflammation; Isoproterenol; Lipid Peroxidation; Lipid

2022
The effects of exercise training on heart, brain and behavior, in the isoproterenol-induced cardiac infarct model in middle-aged female rats.
    Scientific reports, 2022, 06-16, Volume: 12, Issue:1

    Topics: Animals; Brain; Female; Humans; Isoproterenol; Myocardial Infarction; Myocardium; Rats; Rats, Wistar

2022
A novel synthetised sulphonylhydrazone coumarin (E)-4-methyl-N'-(1-(3-oxo-3H-benzo[f]chromen-2- yl)ethylidene)benzenesulphonohydrazide protect against isoproterenol-induced myocardial infarction in rats by attenuating oxidative damage, biological changes
    Clinical and experimental pharmacology & physiology, 2022, Volume: 49, Issue:9

    Topics: Animals; Antioxidants; Body Weight; Cardiotonic Agents; Catalase; Coumarins; Electrocardiography; Gl

2022
In vivo evaluation and molecular docking studies of Schinus molle L. fruit extract protective effect against isoproterenol-induced infarction in rats.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:53

    Topics: Anacardiaceae; Animals; Antioxidants; bcl-2-Associated X Protein; Biomarkers; Caspase 3; Catechin; F

2022
Effect of Fraxetin on Oxidative Damage Caused by Isoproterenol-Induced Myocardial Infarction in Rats.
    Applied biochemistry and biotechnology, 2022, Volume: 194, Issue:12

    Topics: Animals; Antioxidants; Coumarins; Glutathione; Isoproterenol; Lipid Peroxidation; Mice; Myocardial I

2022
Thymoquinone Produces Cardioprotective Effect in β-Receptor Stimulated Myocardial Infarcted Rats via Subsiding Oxidative Stress and Inflammation.
    Nutrients, 2022, Jun-30, Volume: 14, Issue:13

    Topics: Animals; Benzoquinones; Cardiotonic Agents; Heart; Inflammation; Isoproterenol; Lipid Peroxidation;

2022
Bergapten mediated inflammatory and apoptosis through AMPK/eNOS/AKT signaling pathway of isoproterenol-induced myocardial infarction in Wistar rats.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:9

    Topics: 5-Methoxypsoralen; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; A

2022
S-limonene protects the heart in an experimental model of myocardial infarction induced by isoproterenol: Possible involvement of mitochondrial reactive oxygen species.
    European journal of pharmacology, 2022, Sep-05, Volume: 930

    Topics: Animals; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Heart Injuries; Isoproter

2022
Evaluation of rosmarinic acid against myocardial infarction in maternally separated rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2022, Volume: 395, Issue:10

    Topics: Animals; Body Weight; Brain-Derived Neurotrophic Factor; Cinnamates; Corticosterone; Depsides; Fluox

2022
Thymoquinone regulates nitric oxide synthase enzymes and receptor-interacting serine-threonine kinases in isoproterenol-induced myocardial infarcted rats.
    Chemico-biological interactions, 2022, Sep-25, Volume: 365

    Topics: Animals; Benzoquinones; Isoproterenol; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Nitric

2022
β-caryophyllene modulates B-cell lymphoma gene-2 family genes and inhibits the intrinsic pathway of apoptosis in isoproterenol-induced myocardial infarcted rats; A molecular mechanism.
    European journal of pharmacology, 2022, Oct-15, Volume: 932

    Topics: Animals; Antioxidants; Apoptosis; Body Weight; Chlorides; Glucuronidase; Isoproterenol; Lipid Peroxi

2022
Comparative Efficacy of Levosimendan, Ramipril, and Sacubitril/ Valsartan in Isoproterenol-induced Experimental Heart Failure: A Hemodynamic and Molecular Approach.
    Current molecular pharmacology, 2023, Volume: 16, Issue:6

    Topics: Antioxidants; Calcium; Collagen; Heart Failure; Hemodynamics; Humans; Isoproterenol; Myocardial Infa

2023
Network Pharmacology-Based Combined with Experimental Validation Study to Explore the Underlying Mechanism of
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Agrimonia; Animals; Antioxidants; Aspartic Acid; bcl-2-Associated X Protein; Caspase 3; Creatine Kin

2022
Cardioprotective Role of Scopoletin on Isoproterenol-Induced Myocardial Infarction in Rats.
    Applied biochemistry and biotechnology, 2023, Volume: 195, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Cardiotonic Agents; Isoproterenol; Myo

2023
Protocatechuic acid reverses myocardial infarction mediated by β-adrenergic agonist via regulation of Nrf2/HO-1 pathway, inflammatory, apoptotic, and fibrotic events.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Isoproterenol; Myocardial Infarction; Myocytes, Car

2023
Protective effects of Lacticaseibacillus rhamnosus on isoprenaline-induced myocardial infarction in rats.
    Journal of applied microbiology, 2023, Jan-23, Volume: 134, Issue:1

    Topics: Animals; Creatine Kinase; Humans; Interleukin-10; Isoproterenol; Lacticaseibacillus; Lacticaseibacil

2023
Evidence of the Cardioprotective Effects of
    Journal of medicinal food, 2023, Volume: 26, Issue:1

    Topics: Animals; Ethanol; Isoproterenol; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Verbenaceae

2023
Vanillin and pentoxifylline ameliorate isoproterenol-induced myocardial injury in rats
    Food & function, 2023, Apr-03, Volume: 14, Issue:7

    Topics: Animals; Inflammation; Isoproterenol; Myocardial Infarction; Myocardium; Oxidative Stress; Pentoxify

2023
The myokine decorin improves the cardiac function in a rat model of isoprenaline-induced myocardial infarction.
    Canadian journal of physiology and pharmacology, 2023, Jun-01, Volume: 101, Issue:6

    Topics: Animals; Caspase 3; Decorin; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wis

2023
Microbiome-metabolome reveals that the Suxiao Jiuxin pill attenuates acute myocardial infarction associated with fatty acid metabolism.
    Journal of ethnopharmacology, 2023, Aug-10, Volume: 312

    Topics: Animals; Drugs, Chinese Herbal; Fatty Acids; Isoproterenol; Metabolome; Metabolomics; Microbiota; My

2023
The effect of bempedoic acid an ATP-citrate lyase inhibitor on cardiovascular risk factors in rats with experimentally induced myocardial infarction and hyperlipidemia.
    Cellular and molecular biology (Noisy-le-Grand, France), 2022, Sep-30, Volume: 68, Issue:10

    Topics: Adenosine Triphosphate; Animals; Cardiovascular Diseases; Cholesterol, LDL; Enzyme Inhibitors; Fatty

2022
Protective effects of β-caryophyllene on mitochondrial damage and cardiac hypertrophy pathways in isoproterenol-induced myocardial infarcted rats.
    European journal of pharmacology, 2023, Aug-05, Volume: 952

    Topics: Animals; Antioxidants; Biomarkers; Body Weight; Cardiomegaly; Isoproterenol; Mitochondria, Heart; My

2023
Effects of Taraxerol on Oxidative and Inflammatory Mediators in Isoproterenol-Induced Cardiotoxicity in an Animal Model.
    Molecules (Basel, Switzerland), 2023, May-15, Volume: 28, Issue:10

    Topics: Animals; Antioxidants; Cardiotoxicity; Disease Models, Animal; Inflammation Mediators; Isoproterenol

2023
Curdione inhibits ferroptosis in isoprenaline-induced myocardial infarction via regulating Keap1/Trx1/GPX4 signaling pathway.
    Phytotherapy research : PTR, 2023, Volume: 37, Issue:11

    Topics: Animals; Ferroptosis; Glutathione; Isoproterenol; Kelch-Like ECH-Associated Protein 1; Mice; Molecul

2023
Cardioprotective effects of Schisantherin A against isoproterenol-induced acute myocardial infarction through amelioration of oxidative stress and inflammation via modulation of PI3K-AKT/Nrf2/ARE and TLR4/MAPK/NF-κB pathways in rats.
    BMC complementary medicine and therapies, 2023, Aug-04, Volume: 23, Issue:1

    Topics: Animals; Body Weight; Inflammation; Isoproterenol; Myocardial Infarction; NF-E2-Related Factor 2; NF

2023
Effect of essential oil of Alpinia zerumbet on cardiovascular and autonomic function in rats with isoproterenol induced acute myocardial infarction.
    Anais da Academia Brasileira de Ciencias, 2023, Volume: 95, Issue:suppl 1

    Topics: Alpinia; Animals; Isoproterenol; Myocardial Infarction; Oils, Volatile; Plant Leaves; Rats; Rats, Wi

2023
Anti-inflammatory, cardioprotective effect of gypenoside against isoproterenol-induced cardiac remodeling in rats via alteration of inflammation and gut microbiota.
    Inflammopharmacology, 2023, Volume: 31, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cytokines; Gastrointestinal Microbiome;

2023
Punicalagin attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats: Biochemical, immunohistochemical, and in silico molecular docking studies.
    Chemico-biological interactions, 2023, Nov-01, Volume: 385

    Topics: Animals; Antioxidants; Apoptosis; Cytokines; Hydrolyzable Tannins; Inflammation; Isoproterenol; Mole

2023
β-caryophyllene blocks reactive oxygen species-mediated hyperlipidemia in isoproterenol-induced myocardial infarcted rats.
    European journal of pharmacology, 2023, Dec-05, Volume: 960

    Topics: Animals; Antioxidants; Body Weight; Cholesterol; Hyperlipidemias; Isoproterenol; Lipoproteins, LDL;

2023
Cardioprotective effects of (
    Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:10

    Topics: Animals; Benzopyrans; Biomarkers; Cardiotonic Agents; Coumarins; Disease Models, Animal; Electrocard

2019
Anti-Ischemic Activity of Triamine ALM-802 under Conditions of Endothelial Dysfunction.
    Bulletin of experimental biology and medicine, 2019, Volume: 167, Issue:4

    Topics: Animals; Electrophysiology; Hyperhomocysteinemia; Isoproterenol; Male; Myocardial Infarction; Ranola

2019
Cardioprotective potential of
    Archives of physiology and biochemistry, 2022, Volume: 128, Issue:1

    Topics: Animals; Antioxidants; Isoproterenol; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Spinaci

2022
Pharmacodynamics and pharmacokinetics of Danshen in isoproterenol-induced acute myocardial ischemic injury combined with Honghua.
    Journal of ethnopharmacology, 2020, Jan-30, Volume: 247

    Topics: Administration, Oral; Animals; Carthamus tinctorius; China; Disease Models, Animal; Drug Combination

2020
Effect of lncRNA GAS5 on rats with acute myocardial infarction through regulating miR-21.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:19

    Topics: Acute Disease; Animals; Disease Models, Animal; Injections, Subcutaneous; Isoproterenol; MicroRNAs;

2019
Cardio protective role of wogonin loaded nanoparticle against isoproterenol induced myocardial infarction by moderating oxidative stress and inflammation.
    Colloids and surfaces. B, Biointerfaces, 2020, Jan-01, Volume: 185

    Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Cytokines; Drug Liberation; Flavanones; Heme

2020
Protective Effect of Sciadopitysin against Isoproternol-Induced Myocardial Infarction in Rats.
    Pharmacology, 2020, Volume: 105, Issue:5-6

    Topics: Animals; Biflavonoids; Cardiotonic Agents; Heart; Isoproterenol; Male; Myocardial Infarction; Myocar

2020
Gold nanoparticles synthesized from Euphorbia fischeriana root by green route method alleviates the isoprenaline hydrochloride induced myocardial infarction in rats.
    Journal of photochemistry and photobiology. B, Biology, 2020, Volume: 202

    Topics: Animals; Antioxidants; Catalase; Creatine Kinase; Cytokines; Euphorbia; Gold; Green Chemistry Techno

2020
Protective role of poly(lactic-co-glycolic) acid nanoparticle loaded with resveratrol against isoproterenol-induced myocardial infarction.
    BioFactors (Oxford, England), 2020, Volume: 46, Issue:3

    Topics: Animals; Antioxidants; Biocompatible Materials; Cardiotonic Agents; Disease Models, Animal; Isoprote

2020
Rosuvastatin and retinoic acid may act as 'pleiotropic agents' against β-adrenergic agonist-induced acute myocardial injury through modulation of multiple signalling pathways.
    Chemico-biological interactions, 2020, Feb-25, Volume: 318

    Topics: Adrenergic beta-Agonists; Animals; Anticholesteremic Agents; Antineoplastic Agents; Body Weight; Hea

2020
Therapeutic Potential of Biochanin-A Against Isoproterenol-Induced Myocardial Infarction in Rats.
    Cardiovascular & hematological agents in medicinal chemistry, 2020, Volume: 18, Issue:1

    Topics: Animals; Cardiotonic Agents; Genistein; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarcti

2020
(E)-N'-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Benzopyrans; Biomarkers; Coumarins; Hydrazones; Inflam

2020
Protective effects and chemical composition of Corchorus olitorius leaf fractions against isoproterenol-induced myocardial injury through p65NFkB-dependent anti-apoptotic pathway in rats.
    Journal of basic and clinical physiology and pharmacology, 2020, Apr-21, Volume: 31, Issue:5

    Topics: Animals; Apoptosis; Cardiotonic Agents; Corchorus; Disease Models, Animal; Dose-Response Relationshi

2020
The role of 5-HT7 receptors on isoproterenol-induced myocardial infarction in rats with high-fat diet exacerbated coronary endothelial dysfunction.
    Human & experimental toxicology, 2020, Volume: 39, Issue:8

    Topics: Animals; Cell Line; Cell Proliferation; Diet, High-Fat; Endothelium, Vascular; Heart; Isoproterenol;

2020
Design and Development of Novel Pyrazole-Thiadiazole Derivatives as NF-ĸB Inhibitor and Cardioprotective Effect against Isoproterenol Induced Myocardial Infarction in Sprague-Dawley Rats.
    Pharmacology, 2020, Volume: 105, Issue:5-6

    Topics: Animals; Apoptosis; Cardiotonic Agents; Heart; Isoproterenol; Myocardial Infarction; Myocardium; Myo

2020
Gentianella acuta prevents acute myocardial infarction induced by isoproterenol in rats via inhibition of galectin-3/TLR4/MyD88/NF-кB inflammatory signalling.
    Inflammopharmacology, 2021, Volume: 29, Issue:1

    Topics: Animals; Apoptosis; Cardiotonic Agents; Cytokines; Galectin 3; Gentianella; Inflammation; Isoprotere

2021
Beneficial effects of benfotiamine, a NADPH oxidase inhibitor, in isoproterenol-induced myocardial infarction in rats.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: Animals; Biomarkers; Cardiotoxins; Disease Models, Animal; Electrocardiography; Enzyme Inhibitors; H

2020
Alterations of medial prefrontal cortex bioelectrical activity in experimental model of isoprenaline-induced myocardial infarction.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: Animals; Brain Waves; Disease Models, Animal; Electrocardiography; Electrocorticography; Electroence

2020
The Expression of microRNA in Adult Rat Heart with Isoproterenol-Induced Cardiac Hypertrophy.
    Cells, 2020, 05-08, Volume: 9, Issue:5

    Topics: Aging; Animals; Atrial Natriuretic Factor; Base Sequence; Cardiomegaly; Gene Expression Regulation,

2020
Role of nitric oxide in mediating the cardioprotective effect of agomelatine against isoproterenol-induced myocardial injury in rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2020, Volume: 393, Issue:10

    Topics: Acetamides; Animals; Cardiotonic Agents; Isoproterenol; Male; Myocardial Infarction; Myocardium; NAD

2020
Ex vivo and in vivo studies of Viola tricolor Linn. as potential cardio protective and hypotensive agent: Inhibition of voltage-gated Ca
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:7

    Topics: Animals; Calcium Channels; Cardiotonic Agents; Hypotension; Isoproterenol; Male; Myocardial Infarcti

2020
Fasudil protects against isoproterenol-induced myocardial infarction in mice via inhibiting Rho/ROCK signaling pathway.
    European review for medical and pharmacological sciences, 2020, Volume: 24, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Dose-Response Relationship, Drug; Injections

2020
Cardioprotective effects of memantine in myocardial ischemia: Ex vivo and in vivo studies.
    European journal of pharmacology, 2020, Sep-05, Volume: 882

    Topics: Animals; Cardiomegaly; Cardiotonic Agents; Isoproterenol; Lipid Peroxidation; Male; Malondialdehyde;

2020
Hirudin protects against isoproternol-induced myocardial infraction by alleviating oxidative via an Nrf2 dependent manner.
    International journal of biological macromolecules, 2020, Nov-01, Volume: 162

    Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Hypoxia; Cell Line; Cell Survival; Creatine Kinase, MB

2020
Intermittent β-adrenergic blockade downregulates the gene expression of β-myosin heavy chain in the mouse heart.
    European journal of pharmacology, 2020, Sep-05, Volume: 882

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Down-Regulation; Female; Isoproteren

2020
Protective effect of alpha-pinene against isoproterenol-induced myocardial infarction through NF-κB signaling pathway.
    Human & experimental toxicology, 2020, Volume: 39, Issue:12

    Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Bicyclic Monoterpenes; Cardiotonic Agen

2020
Preparation of Ginkgolide Solid Dispersions with Low-Molecular-Weight Chitosan and Assessment of their Protective Effect on Isoproterenol- Induced Myocardial Injury.
    Current drug delivery, 2020, Volume: 17, Issue:8

    Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Cardiotonic Agents; Chitos

2020
Sinapic acid safeguards cardiac mitochondria from damage in isoproterenol-induced myocardial infarcted rats.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:10

    Topics: Adrenergic beta-Agonists; Animals; Biomarkers; Cardiotonic Agents; Coumaric Acids; Isoproterenol; Ma

2020
Arbutin prevents alterations in mitochondrial and lysosomal enzymes in isoproterenol-induced myocardial infarction: An in vivo study.
    Human & experimental toxicology, 2021, Volume: 40, Issue:1

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arbutin; Cathep

2021
Protective Effects of Allicin on ISO-Induced Rat Model of Myocardial Infarction via JNK Signaling Pathway.
    Pharmacology, 2020, Volume: 105, Issue:9-10

    Topics: Animals; Antioxidants; Apoptosis; Disease Models, Animal; Disulfides; Isoproterenol; JNK Mitogen-Act

2020
Novel thiazole-pyrazolone hybrids as potent ACE inhibitors and their cardioprotective effect on isoproterenol-induced myocardial infarction.
    Archiv der Pharmazie, 2020, Volume: 353, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cytokin

2020
Beneficial effect of sodium thiosulfate extends beyond myocardial tissue in isoproterenol model of infarction: Implication for nootropic effects.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:12

    Topics: Animals; Behavior, Animal; Disease Models, Animal; Heart; Hydrogen Sulfide; Isoproterenol; Male; Mit

2020
The protective effect of piperine against isoproterenol-induced inflammation in experimental models of myocardial toxicity.
    European journal of pharmacology, 2020, Oct-15, Volume: 885

    Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Benzodioxoles; Cardiomegaly; Cytokines; Endothelium; F

2020
Protective Effect of Boric Acid and Omega-3 on Myocardial Infarction in an Experimental Rat Model.
    Biological trace element research, 2021, Volume: 199, Issue:7

    Topics: Animals; Boric Acids; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Da

2021
Regenerative Potential of a Suspension and Spheroids of Multipotent Mesenchymal Stromal Cells from Human Umbilical Cord on the Model of Myocardial Infarction in Rats.
    Bulletin of experimental biology and medicine, 2020, Volume: 169, Issue:4

    Topics: Animals; Disease Models, Animal; Endomyocardial Fibrosis; Heart Ventricles; Humans; Isoproterenol; M

2020
Ameliorative effect of ferruginol on isoprenaline hydrochloride-induced myocardial infarction in rats.
    Environmental toxicology, 2021, Volume: 36, Issue:2

    Topics: Abietanes; Animals; Antioxidants; Biomarkers; Catalase; Disease Models, Animal; Glutathione Peroxida

2021
Ivabradine improves survival and attenuates cardiac remodeling in isoproterenol-induced myocardial injury.
    Fundamental & clinical pharmacology, 2021, Volume: 35, Issue:4

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Heart Failure; Isoproterenol; Ivabradine; Male;

2021
Adrenergic supersensitivity and impaired neural control of cardiac electrophysiology following regional cardiac sympathetic nerve loss.
    Scientific reports, 2020, 11-02, Volume: 10, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Electrophysiology; Heart; Isoprot

2020
Anti-inflammatory and anti-apoptotic effect of zingiberene on isoproterenol-induced myocardial infarction in experimental animals.
    Human & experimental toxicology, 2021, Volume: 40, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Humans; Inflammation; Isoproterenol; Male; Models, Ani

2021
Type 2 MI induced by a single high dose of isoproterenol in C57BL/6J mice triggers a persistent adaptive immune response against the heart.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:1

    Topics: Adaptive Immunity; Adoptive Transfer; Animals; Dendritic Cells; Disease Models, Animal; Female; Fibr

2021
Early nebivolol treatment is beneficial in myocardial infarction in rats partly through β3-adrenoceptor remodelling.
    Clinical and experimental pharmacology & physiology, 2021, Volume: 48, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Isoproterenol; Male; Myocardial Infarction; Nebivolol; Rats; R

2021
Kuanxiong aerosol inhibits apoptosis and attenuates isoproterenol-induced myocardial injury through the mitogen-activated protein kinase pathway.
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Aerosols; Animals; Apoptosis; bcl-2-Associated X Protein; Cardiotonic Agents; Caspase 3; Down-Regula

2021
Calycosin reduces infarct size, oxidative stress and preserve heart function in isoproterenol-induced myocardial infarction model.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:3(Special)

    Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cardiovascular Agents; Disease Mode

2020
Protective effects of myrrh essential oil on isoproterenol-induced myocardial infarction in rats through antioxidant, anti-inflammatory, Nrf2/HO-1 and apoptotic pathways.
    Journal of ethnopharmacology, 2021, Apr-24, Volume: 270

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Blood Pressure; Cardiotonic

2021
Effect of engineered superparamagnetic iron oxide nanoparticles in targeted cardiac precursor cell delivery by MRI.
    Biochemical and biophysical research communications, 2021, 02-19, Volume: 541

    Topics: Animals; Antibodies, Monoclonal; Cell Separation; Drug Delivery Systems; Echocardiography; Injection

2021
The cardioprotective effect of microRNA-103 inhibitor against isoprenaline-induced myocardial infarction in mice through targeting FADD/RIPK pathway.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:2

    Topics: Animals; Cardiotonic Agents; Fas-Associated Death Domain Protein; Isoproterenol; Male; Mice; MicroRN

2021
Cardiopreventive capacity of a novel (E)-N'-(1-(7-methoxy-2-oxo-2H-chromen-3-yl) ethylidene)-4-methylbenzenesulfonohydrazide against isoproterenol-induced myocardial infarction by moderating biochemical, oxidative stress, and histological parameters.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:6

    Topics: Animals; Benzenesulfonates; Cardiotonic Agents; Isoproterenol; Male; Myocardial Infarction; Myocardi

2021
Nootkatone attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2021, Volume: 84

    Topics: Animals; Apoptosis; Heart; Inflammation; Isoproterenol; Male; Myocardial Infarction; Myocardium; Oxi

2021
Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:5

    Topics: Animals; Cytokines; Inflammation; Interleukin-6; Isoproterenol; Lipids; Matrix Metalloproteinase 2;

2022
Human amniotic membrane mesenchymal stem cells exert cardioprotective effects against isoproterenol (ISO)-induced myocardial injury through suppression of inflammation and modulation of inflammatory MAPK/NF-κB pathway.
    Cell and tissue banking, 2022, Volume: 23, Issue:1

    Topics: Amnion; Humans; Inflammation; Isoproterenol; Mesenchymal Stem Cells; Myocardial Infarction; NF-kappa

2022
Nanostructured lipid carriers of isradipine for effective management of hypertension and isoproterenol induced myocardial infarction.
    Drug delivery and translational research, 2022, Volume: 12, Issue:3

    Topics: Administration, Oral; Animals; Antioxidants; Drug Carriers; Hypertension; Isoproterenol; Isradipine;

2022
Translocator Protein Modulation by 4'-Chlorodiazepam and NO Synthase Inhibition Affect Cardiac Oxidative Stress, Cardiometabolic and Inflammatory Markers in Isoprenaline-Induced Rat Myocardial Infarction.
    International journal of molecular sciences, 2021, Mar-11, Volume: 22, Issue:6

    Topics: Animals; Benzodiazepinones; Biomarkers; Carrier Proteins; Enzyme Inhibitors; Glutathione Peroxidase;

2021
Passiflora edulis (var. Flavicarpa) Juice Supplementation Mitigates Isoproterenol-induced Myocardial Infarction in Rats.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2021, Volume: 76, Issue:2

    Topics: Animals; Antioxidants; Cardiotonic Agents; Dietary Supplements; Isoproterenol; Myocardial Infarction

2021
Time-dependent influence of infliximab on hemodynamic responses and cardiac injuries of isoproterenol-induced myocardial infarction in rats.
    European journal of pharmacology, 2021, Jul-15, Volume: 903

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Disease Models, Animal; Heart Injuries

2021
Nuciferine from Nelumbo nucifera Gaertn. attenuates isoproterenol-induced myocardial infarction in Wistar rats.
    Biotechnology and applied biochemistry, 2022, Volume: 69, Issue:3

    Topics: Animals; Antioxidants; Aporphines; Body Weight; Isoproterenol; Myocardial Infarction; Myocardium; Ne

2022
Andrographolide protects against isoproterenol-induced myocardial infarction in rats through inhibition of L-type Ca
    European journal of pharmacology, 2021, Sep-05, Volume: 906

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiotonic Agents;

2021
Rosuvastatin and low-dose carvedilol combination protects against isoprenaline-induced myocardial infarction in rats: Role of PI3K/Akt/Nrf2/HO-1 signalling.
    Clinical and experimental pharmacology & physiology, 2021, Volume: 48, Issue:10

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anticholesteremic Agents; Apoptosis;

2021
Inhibition of double stranded RNA dependent protein kinase (PKR) abrogates isoproterenol induced myocardial ischemia in vitro in cultured cardiomyocytes and in vivo in wistar rats.
    European journal of pharmacology, 2021, Sep-05, Volume: 906

    Topics: Animals; Cell Line; Disease Models, Animal; eIF-2 Kinase; Fibrosis; Heart; Humans; Isoproterenol; Ma

2021
The cardioprotective effect of astaxanthin against isoprenaline-induced myocardial injury in rats: involvement of TLR4/NF-κB signaling pathway.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:11

    Topics: Animals; Cardiotonic Agents; Isoproterenol; Male; Malondialdehyde; Myocardial Infarction; Myocardium

2021
Thymoquinone dose-dependently attenuates myocardial injury induced by isoproterenol in rats via integrated modulations of oxidative stress, inflammation, apoptosis, autophagy, and fibrosis.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:8

    Topics: Animals; Antioxidants; Apoptosis; Autophagy; Benzoquinones; Cardiotonic Agents; Disease Progression;

2021
Exploring cardioprotective potential of esculetin against isoproterenol induced myocardial toxicity in rats: in vivo and in vitro evidence.
    BMC pharmacology & toxicology, 2021, 07-15, Volume: 22, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Arsenic; Biphenyl Compounds; Cardiotonic Agents; Cell Line; Cell

2021
Lutein exerts its cardioprotective effect against the experimental model of isoprenaline-induced myocardial infarction via MIAT/miR-200a/Nrf2/TXINP pathway.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:11

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Isoproterenol; Lutein; MicroRNAs; Myocardial In

2021
Aqueous extract from leaf of Artocarpus altilis provides cardio-protection from isoproterenol induced myocardial damage in rats: Negative chronotropic and inotropic effects.
    Journal of ethnopharmacology, 2017, May-05, Volume: 203

    Topics: Animals; Artocarpus; Cardiotonic Agents; Dose-Response Relationship, Drug; Herb-Drug Interactions; I

2017
Comprehensive metabonomic analysis of heart tissue from isoproterenol-induced myocardial infarction rat based on reversed-phase and hydrophilic interaction chromatography coupled to mass spectrometry.
    Journal of separation science, 2017, Volume: 40, Issue:10

    Topics: Animals; Chromatography, High Pressure Liquid; Heart; Hydrophobic and Hydrophilic Interactions; Isop

2017
The Protective Effect of Apigenin on Myocardial Injury in Diabetic Rats mediating Activation of the PPAR-γ Pathway.
    International journal of molecular sciences, 2017, Apr-04, Volume: 18, Issue:4

    Topics: Anilides; Animals; Apigenin; Blotting, Western; Cardiotonic Agents; Creatine Kinase, MB Form; Diabet

2017
Protective Role of N-Acetylcysteine on Isoprenaline-Induced Myocardial Injury: Histological, Immunohistochemical and Morphometric Study.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:1

    Topics: Acetylcysteine; Actins; Animals; Collagen; Cytoprotection; Disease Models, Animal; Immunohistochemis

2018
Cardioprotective Effects of Malvidin Against Isoproterenol-Induced Myocardial Infarction in Rats: A Mechanistic Study.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Apr-26, Volume: 23

    Topics: Animals; Anthocyanins; Antioxidants; Catalase; Enzyme-Linked Immunosorbent Assay; Glutathione Peroxi

2017
Astaxanthin Prevented Oxidative Stress in Heart and Kidneys of Isoproterenol-Administered Aged Rats.
    Journal of dietary supplements, 2018, Jan-02, Volume: 15, Issue:1

    Topics: Animals; Antioxidants; Cardiomegaly; Heart; Isoproterenol; Kidney; Lipid Peroxidation; Male; Myocard

2018
Trace Element Determination and Cardioprotection of Terminalia pallida Fruit Ethanolic Extract in Isoproterenol Induced Myocardial Infarcted Rats by ICP-MS.
    Biological trace element research, 2018, Volume: 181, Issue:1

    Topics: Animals; Ethanol; Fruit; Isoproterenol; Male; Minerals; Myocardial Infarction; Plant Extracts; Rats;

2018
In vivo and molecular docking studies using whole extract and phytocompounds of Aegle marmelos fruit protective effects against Isoproterenol-induced Myocardial infarction in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 91

    Topics: Aegle; Animals; Cardiotonic Agents; Fruit; Isoproterenol; Male; Molecular Docking Simulation; Myocar

2017
Molecular assessment of protective effect of Vitex negundo in ISO induced myocardial infarction in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Animals; Cardiotonic Agents; Isoproterenol; Male; Myocardial Infarction; NF-kappa B; Proto-Oncogene

2017
Protective effect of diethylcarbamazine inhibits NF-κB activation in isoproterenol-induced acute myocardial infarction rat model through the PARP pathway.
    Molecular medicine reports, 2017, Volume: 16, Issue:2

    Topics: Animals; Casein Kinases; Cyclooxygenase 2; Diethylcarbamazine; Disease Models, Animal; I-kappa B Pro

2017
Cardiopreventive effect of ethanolic extract of Date Palm Pollen against isoproterenol induced myocardial infarction in rats through the inhibition of the angiotensin-converting enzyme.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2017, Oct-02, Volume: 69, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Cardiotonic Agents; Disease Models, A

2017
Cardiaprotective effect of crocetin by attenuating apoptosis in isoproterenol induced myocardial infarction rat model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 93

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Cardiotonic Agents; Carotenoids; Caspase

2017
Cardioprotective effect of nesfatin-1 against isoproterenol-induced myocardial infarction in rats: Role of the Akt/GSK-3β pathway.
    Peptides, 2017, Volume: 95

    Topics: Animals; Apoptosis; Calcium-Binding Proteins; Cardiotonic Agents; Disease Models, Animal; DNA-Bindin

2017
Anthocyanin rich extract of Brassica oleracea L. alleviates experimentally induced myocardial infarction.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Animals; Animals, Newborn; Anthocyanins; Antioxidants; Apoptosis; Brassica; Caveolin 3; Gene Express

2017
Protective effects of ethanolic peel and pulp extracts of Citrus macroptera fruit against isoproterenol-induced myocardial infarction in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 94

    Topics: Animals; Antioxidants; Cardiotonic Agents; Citrus; Disease Models, Animal; Fruit; Isoproterenol; Mal

2017
Diosmin Prevents Isoproterenol-Induced Heart Mitochondrial Oxidative Stress in Rats.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:2

    Topics: Animals; Antioxidants; Biomarkers; Calcium Signaling; Cardiotoxicity; Cytoprotection; Diosmin; Disea

2018
The Effects of Periostin in a Rat Model of Isoproterenol: Mediated Cardiotoxicity.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:2

    Topics: Animals; Apoptosis; Cardiotoxicity; Cell Adhesion Molecules; Cell Proliferation; Cytoprotection; Dis

2018
Histological and immunohistochemical study of cardiac telocytes in a rat model of isoproterenol-induced myocardial infarction with a reference to the effect of grape seed extract.
    Acta histochemica, 2017, Volume: 119, Issue:7

    Topics: Animals; Antioxidants; Disease Models, Animal; Grape Seed Extract; Heart Ventricles; Immunohistochem

2017
Inhibition of NADPH oxidase by apocynin promotes myocardial antioxidant response and prevents isoproterenol-induced myocardial oxidative stress in rats.
    Free radical research, 2017, Volume: 51, Issue:9-10

    Topics: Acetophenones; Animals; Antioxidants; Cardiotonic Agents; Drug Evaluation, Preclinical; Isoprotereno

2017
Renin Inhibition by Aliskiren Protects Rats Against Isoproterenol Induced Myocardial Infarction.
    Drug research, 2018, Volume: 68, Issue:3

    Topics: Amides; Animals; Biomarkers; Cardiotonic Agents; Catalase; Creatine Kinase, MB Form; Dose-Response R

2018
A molecular mechanism on the antiapoptotic effects of zingerone in isoproterenol induced myocardial infarcted rats.
    European journal of pharmacology, 2018, Feb-15, Volume: 821

    Topics: Animals; Antioxidants; Apoptosis; Caspases; fas Receptor; Guaiacol; Isoproterenol; Male; Myocardial

2018
Oligomeric proanthocyanidins protect myocardium by mitigating left ventricular remodeling in isoproterenol-induced postmyocardial infarction.
    Fundamental & clinical pharmacology, 2018, Volume: 32, Issue:1

    Topics: Animals; Antioxidants; Bone Morphogenetic Protein 4; Cardiovascular Agents; Collagen; Disease Models

2018
Novel Mesenchymal Stem Cell Strategy in Alleviating Toll-Like Receptor-4, p53 and Nrf2 Signaling in Isoproterenol-Induced Myocardial Infarction in Rat Model.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:3

    Topics: Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Isoproterenol; Male; Mesenchymal Stem C

2018
Resident fibroblast expansion during cardiac growth and remodeling.
    Journal of molecular and cellular cardiology, 2018, Volume: 114

    Topics: Animals; Animals, Newborn; Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cell Lineage; Ce

2018
Effect of Atractylodes macrocephala rhizoma on isoproterenol‑induced ventricular remodeling in rats.
    Molecular medicine reports, 2018, Volume: 17, Issue:2

    Topics: Animals; Antioxidants; Atractylodes; Biomarkers; Heart Ventricles; Hemodynamics; Isoproterenol; Male

2018
Periostin normalizes levels of cardiac markers in rats with experimental isoproterenol cardiotoxicity.
    Bratislavske lekarske listy, 2017, Volume: 118, Issue:11

    Topics: Alanine Transaminase; Animals; Antioxidants; Cardiotoxicity; Catalase; Cell Adhesion Molecules; Isop

2017
Raspberry ketone protects against isoproterenol-induced myocardial infarction in rats.
    Life sciences, 2018, Feb-01, Volume: 194

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Butanones; Cardiotonic Agents; Isoproterenol; Myoca

2018
Cardioprotective Mechanisms of Exenatide in Isoprenaline-induced Myocardial Infarction: Novel Effects on Myocardial α-Estrogen Receptor Expression and IGF-1/IGF-2 System.
    Journal of cardiovascular pharmacology, 2018, Volume: 71, Issue:3

    Topics: Animals; Apoptosis; Cytoprotection; Disease Models, Animal; Estradiol; Estrogen Receptor alpha; Exen

2018
Effect of Kaempferol Pretreatment on Myocardial Injury in Rats.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:4

    Topics: Animals; Antioxidants; Biomarkers; Cytoprotection; Disease Models, Animal; Dose-Response Relationshi

2018
Vitexin protects isoproterenol induced post myocardial injury by modulating hipposignaling and ER stress responses.
    Biochemical and biophysical research communications, 2018, 02-05, Volume: 496, Issue:2

    Topics: Animals; Antioxidants; Apigenin; Apoptosis; Cardiotonic Agents; Caspase 3; Endoplasmic Reticulum Str

2018
Imaging of isoproterenol-induced myocardial injury with
    Nuclear medicine and biology, 2018, Volume: 59

    Topics: Animals; Biological Transport; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug;

2018
Protective Effects of Olive Leaf Extract on Acrolein-Exacerbated Myocardial Infarction via an Endoplasmic Reticulum Stress Pathway.
    International journal of molecular sciences, 2018, Feb-07, Volume: 19, Issue:2

    Topics: Acrolein; Animals; Apoptosis; Biological Products; Biomarkers; Cell Line; Cytoprotection; Disease Pr

2018
A Strategy for Optimizing the Combination of Active Components Based on Chinese Medicinal Formula Sheng-Mai-San for Myocardial Ischemia.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 45, Issue:4

    Topics: Animals; Creatine Kinase, MB Form; Cyclooctanes; Disease Models, Animal; Drug Combinations; Drugs, C

2018
Cardioprotective effect of vitamin D
    Archives of physiology and biochemistry, 2019, Volume: 125, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Blood Glucose; Cardiotonic Agents; Diabetes Mellitus, Experimenta

2019
Cardioprotective effect of rosuvastatin against isoproterenol-induced myocardial infarction injury in rats.
    International journal of molecular medicine, 2018, Volume: 41, Issue:6

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Glutathione; Glutathione P

2018
Sacubitril and valsartan protect from experimental myocardial infarction by ameliorating oxidative damage in Wistar rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2019, Volume: 41, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Aminobutyrates; Animals; Antihypertensive Agents; Antiox

2019
Sitagliptin prevents isoproterenol-induced myocardial infarction in rats by modulating nitric oxide synthase enzymes.
    European journal of pharmacology, 2018, Jun-15, Volume: 829

    Topics: Animals; Blood Glucose; Fasting; Isoproterenol; Male; Myocardial Infarction; Myocardium; Nitric Oxid

2018
Cardioprotective and Anti-Aggregatory Effects of Levosimendan on Isoproterenol-Induced Myocardial Injury in High-Fat-Fed Rats Involves Modulation of PI3K/Akt/mTOR Signaling Pathway and Inhibition of Apoptosis: Comparison to Cilostazol.
    Journal of cardiovascular pharmacology and therapeutics, 2018, Volume: 23, Issue:5

    Topics: Animals; Apoptosis; Cilostazol; Diet, High-Fat; Disease Models, Animal; Heart Rate; Inflammation Med

2018
Cardioprotective effect of Amaranthus tricolor extract in isoprenaline induced myocardial damage in ovariectomized rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103

    Topics: Amaranthus; Animals; Cardiotonic Agents; Disease Models, Animal; Female; Isoproterenol; Myocardial I

2018
Catalpol pretreatment attenuates cardiac dysfunction following myocardial infarction in rats.
    Anatolian journal of cardiology, 2018, Volume: 19, Issue:5

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Drugs, Chinese Herbal; Iridoid Glucosides; Isop

2018
Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 104

    Topics: Animals; Antioxidants; Atorvastatin; Biomarkers; Cardiotonic Agents; Cardiotoxicity; Heart; Inflamma

2018
Cyanobacteria as Nanogold Factories: Chemical and Anti-Myocardial Infarction Properties of Gold Nanoparticles Synthesized by
    Marine drugs, 2018, Jun-20, Volume: 16, Issue:6

    Topics: Animals; Antioxidants; Aquatic Organisms; Biomarkers; Biotechnology; Blood Pressure; Cardiotonic Age

2018
Combined and individual strategy of exercise generated preconditioning and low dose copper nanoparticles serve as superlative approach to ameliorate ISO-induced myocardial infarction in rats.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:4

    Topics: Androstadienes; Animals; Cardiotonic Agents; Copper; Creatine Kinase, MB Form; Glycogen Synthase Kin

2018
Effects of low dose of aliskiren on isoproterenol-induced acute myocardial infarction in rats.
    Physiology international, 2018, Jun-01, Volume: 105, Issue:2

    Topics: Amides; Animals; Apoptosis; Cardiotonic Agents; Fumarates; Isoproterenol; Male; Myocardial Infarctio

2018
Effect of ethanolic extract of Cyperus rotundus L. against isoprenaline induced cardiotoxicity.
    Indian journal of experimental biology, 2016, Volume: 54, Issue:10

    Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarker

2016
Protective effects of α-bisabolol on altered hemodynamics, lipid peroxidation, and nonenzymatic antioxidants in isoproterenol-induced myocardial infarction: In vivo and in vitro evidences.
    Journal of biochemical and molecular toxicology, 2018, Volume: 32, Issue:10

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Creatine Kinase; Creatine Kinase, MB Form; Hemodyna

2018
Cardioprotective role of FA against isoproterenol induced cardiac toxicity.
    Molecular biology reports, 2018, Volume: 45, Issue:5

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Cardiotonic Agents; Cardioto

2018
Anti-fibrotic Actions of Roselle Extract in Rat Model of Myocardial Infarction.
    Cardiovascular toxicology, 2019, Volume: 19, Issue:1

    Topics: Animals; Atrial Natriuretic Factor; Cardiovascular Agents; Collagen Type I; Collagen Type III; Disea

2019
α-Bisabolol abrogates isoproterenol-induced myocardial infarction by inhibiting mitochondrial dysfunction and intrinsic pathway of apoptosis in rats.
    Molecular and cellular biochemistry, 2019, Volume: 453, Issue:1-2

    Topics: Animals; Apoptosis; Isoproterenol; Male; Mitochondria, Heart; Mitochondrial Proteins; Monocyclic Ses

2019
Pitavastatin ameliorates myocardial damage by preventing inflammation and collagen deposition via reduced free radical generation in isoproterenol-induced cardiomyopathy.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2019, Volume: 41, Issue:5

    Topics: Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Collagen; Creatine Kinase, MB Form; Fr

2019
Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Adenosine Triphosphatases; Animals; Antioxidants; Benzaldehydes; Biomarkers; Cardiotoxicity; Erythro

2018
Evaluation of Paeonia emodi for its cardioprotective potentials: An investigative study towards possible mechanism.
    Journal of ethnopharmacology, 2019, Mar-01, Volume: 231

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Cardiotonic Agents; Creati

2019
Cardioprotective Effects of Curcumin-Nisin Based Poly Lactic Acid Nanoparticle on Myocardial Infarction in Guinea Pigs.
    Scientific reports, 2018, 11-09, Volume: 8, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; C

2018
Suppression of isoproterenol-induced cardiotoxicity in rats by raspberry ketone via activation of peroxisome proliferator activated receptor-α.
    European journal of pharmacology, 2019, Jan-05, Volume: 842

    Topics: Animals; Apolipoprotein C-II; Butanones; Cardiotonic Agents; Caspase 3; Electrocardiography; Gene Ex

2019
The relationship between visfatin and cardiac markers on induced myocardial infarction in rats.
    Cytokine, 2019, Volume: 115

    Topics: Animals; Biomarkers; Disease Models, Animal; Female; Heart; Isoproterenol; Myocardial Infarction; My

2019
Berbamine ameliorates isoproterenol-induced myocardial infarction by inhibiting mitochondrial dysfunction and apoptosis in rats.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:3

    Topics: Animals; Apoptosis; Benzylisoquinolines; Isoproterenol; Male; Mitochondria; Myocardial Infarction; O

2019
Nanoyttria attenuates isoproterenol-induced cardiac injury.
    Nanomedicine (London, England), 2018, Volume: 13, Issue:23

    Topics: Animals; Cardiotoxicity; Cytokines; Gene Expression Regulation; Heart; Heart Injuries; Hydroxyprolin

2018
Resveratrol protects against isoproterenol induced myocardial infarction in rats through VEGF-B/AMPK/eNOS/NO signalling pathway.
    Free radical research, 2019, Volume: 53, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Isoproterenol; Male; Myocardial Infarction; Myocytes, Car

2019
LncRNA MALAT1 protects cardiomyocytes from isoproterenol-induced apoptosis through sponging miR-558 to enhance ULK1-mediated protective autophagy.
    Journal of cellular physiology, 2019, Volume: 234, Issue:7

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Autophagy; Autophagy-Related Protein-1 Homolog; Cell L

2019
Effects of nimodipine, vinpocetine and their combination on isoproterenol-induced myocardial infarction in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Heart; Isoproterenol; Male; Myocardial Infarc

2019
Role of MAPK/NF-κB pathway in cardioprotective effect of Morin in isoproterenol induced myocardial injury in rats.
    Molecular biology reports, 2019, Volume: 46, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Flavonoids; Heart; Isoproterenol; Male; MAP Kinase Signaling Syste

2019
Attenuation of isoproterenol-induced cardiotoxicity in rats by Narirutin rich fraction from grape fruit.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Mar-01, Volume: 55

    Topics: Adrenergic beta-Agonists; Animals; Cardiotoxicity; Citrus paradisi; Disaccharides; Flavanones; Heart

2019
Pretreatment with β-glucan attenuates isoprenaline-induced myocardial injury in rats.
    Experimental physiology, 2019, Volume: 104, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; beta-Glucans; Biomarkers; Cardiotonic Agents; Catalase; Heart; Iso

2019
Linagliptin Suppresses Electrical and Structural Remodeling in the Isoproterenol Induced Myocardial Injury Model.
    International heart journal, 2019, Mar-20, Volume: 60, Issue:2

    Topics: Animals; Antioxidants; Atrial Remodeling; Cardiotonic Agents; Dipeptidyl Peptidase 4; Dipeptidyl-Pep

2019
The protective impact of betaine on the tissue structure and renal function in isoproterenol-induced myocardial infarction in rat.
    Molecular genetics & genomic medicine, 2019, Volume: 7, Issue:4

    Topics: Animals; Betaine; Cardiotonic Agents; Isoproterenol; Kidney; Male; Myocardial Infarction; Myocytes,

2019
Cardioprotective Effect of Rhapontigenin in Isoproterenol-Induced Myocardial Infarction in a Rat Model.
    Pharmacology, 2019, Volume: 103, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cardiotonic Agents; Disease Models, Anim

2019
The protective effect of kaempferol on heart via the regulation of Nrf2, NF-κβ, and PI3K/Akt/GSK-3β signaling pathways in isoproterenol-induced heart failure in diabetic rats.
    Drug development research, 2019, Volume: 80, Issue:3

    Topics: Animals; Cardiotonic Agents; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3 beta; Heart

2019
Phloroglucinol averts isoprenaline hydrochloride induced myocardial infarction in rats.
    Drug development research, 2019, Volume: 80, Issue:4

    Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Electrocardiography; Heart; Isoproterenol; Li

2019
(3R)‑5,6,7‑trihydroxy‑3‑isopropyl‑3‑methylisochroman‑1‑one attenuates cardiac dysfunction via the apelin/APJ signaling pathway.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: Animals; Apelin; Apelin Receptors; bcl-2-Associated X Protein; Blood Pressure; Body Weight; Caspase

2019
Ursolic acid modulates MMPs, collagen-I, α-SMA, and TGF-β expression in isoproterenol-induced myocardial infarction in rats.
    Human & experimental toxicology, 2019, Volume: 38, Issue:7

    Topics: Actins; Animals; Cardiotonic Agents; Collagen Type I; Isoproterenol; Lysosomes; Male; Matrix Metallo

2019
Ameliorative effects of cerebrolysin against isoproterenol-induced myocardial injury in male rats.
    Life sciences, 2019, Jun-15, Volume: 227

    Topics: Amino Acids; Animals; Antioxidants; Catalase; Glutathione Peroxidase; Heart; Isoproterenol; Lipid Pe

2019
Comprehensive Analysis of Animal Models of Cardiovascular Disease using Multiscale X-Ray Phase Contrast Tomography.
    Scientific reports, 2019, 05-06, Volume: 9, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Coronary Vessels; Disease Models, Animal; Heart; Heart Failure; I

2019
β-Caryophyllene as a Potential Protective Agent Against Myocardial Injury: The Role of Toll-Like Receptors.
    Molecules (Basel, Switzerland), 2019, May-19, Volume: 24, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Animals; Biological Products; Blood Pressure; Creatine Kinase;

2019
Oleic Acid Prevents Isoprenaline-Induced Cardiac Injury: Effects on Cellular Oxidative Stress, Inflammation and Histopathological Alterations.
    Cardiovascular toxicology, 2020, Volume: 20, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Disease Models, Animal; Inflammatio

2020
Cardioprotective effect of ranolazine in nondiabetic and diabetic male rats subjected to isoprenaline-induced acute myocardial infarction involves modulation of AMPK and inhibition of apoptosis.
    Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:7

    Topics: Acute Disease; AMP-Activated Protein Kinases; Animals; Apoptosis; Blood Glucose; Cardiotonic Agents;

2019
Cardioprotective effects of cerebrolysin on the lesion severity and inflammatory factors in a rat model of isoproterenol-induced myocardial injury.
    Pharmacological reports : PR, 2019, Volume: 71, Issue:4

    Topics: Amino Acids; Animals; Biomarkers; Cardiotonic Agents; Cell Survival; Coronary Circulation; Interleuk

2019
Effects of Curcumin Nanoparticles in Isoproterenol-Induced Myocardial Infarction.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Curcumin;

2019
Cardioprotective effects induced by hydroalcoholic extract of leaves of Alpinia zerumbet on myocardial infarction in rats.
    Journal of ethnopharmacology, 2019, Oct-05, Volume: 242

    Topics: Alpinia; Animals; Blood Pressure; Cardiotonic Agents; Creatine Kinase; Heart Rate; Isoproterenol; Ma

2019
Cyanobacteria as Nanogold Factories II: Chemical Reactivity and anti-Myocardial Infraction Properties of Customized Gold Nanoparticles Biosynthesized by
    Marine drugs, 2019, Jul-08, Volume: 17, Issue:7

    Topics: Animals; Cyanobacteria; Cyanothece; Gold; Isoproterenol; Light; Male; Metal Nanoparticles; Myocardia

2019
Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:6

    Topics: Administration, Oral; Animals; Arterial Pressure; Cardiotonic Agents; Disease Models, Animal; Dose-R

2012
Cardio protective effect of vitamin A against isoproterenol-induced myocardial infarction.
    Journal of nutritional science and vitaminology, 2012, Volume: 58, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Creatine Kinase; Glutathione;

2012
Examining the relationship between exercise tolerance and isoproterenol-based cardiac reserve in murine models of heart failure.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Volume: 114, Issue:9

    Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Disease Models, Animal; Exercise Test; Exerci

2013
(-) Epicatechin prevents alterations in lysosomal glycohydrolases, cathepsins and reduces myocardial infarct size in isoproterenol-induced myocardial infarcted rats.
    European journal of pharmacology, 2013, Apr-15, Volume: 706, Issue:1-3

    Topics: Animals; Catechin; Cathepsin B; Cathepsin D; Glycoside Hydrolases; Isoproterenol; Lysosomes; Male; M

2013
The novel Mas agonist, CGEN-856S, attenuates isoproterenol-induced cardiac remodeling and myocardial infarction injury in rats.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Cardiomegaly; Cardiotonic Agents; CHO Cells; Collagen; Cricetinae; Cricetulus; Fibronectins

2013
Tomato lycopene attenuates myocardial infarction induced by isoproterenol: electrocardiographic, biochemical and anti-apoptotic study.
    Asian Pacific journal of tropical biomedicine, 2012, Volume: 2, Issue:5

    Topics: Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Carotenoids; Caspase 3; Disease Models, Animal

2012
Preventive effects of p-coumaric acid on cardiac hypertrophy and alterations in electrocardiogram, lipids, and lipoproteins in experimentally induced myocardial infarcted rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 60

    Topics: Animals; Cardiomegaly; Cholesterol; Coumaric Acids; Electrocardiography; Fatty Acids, Nonesterified;

2013
Intravenous human umbilical cord blood improves electrophysiological and metabolic properties in ISO induced myocardial necrosis in rats.
    Indian journal of experimental biology, 2013, Volume: 51, Issue:3

    Topics: Animals; Antioxidants; Blood Pressure; Cardiotoxins; Creatine Kinase; Dose-Response Relationship, Dr

2013
Screening and identifying the myocardial-injury protective ingredients from Sheng-Mai-San.
    Pharmaceutical biology, 2013, Volume: 51, Issue:10

    Topics: Animals; Biomarkers; Cardiovascular Agents; Chromatography, Liquid; Creatine Kinase; Cytoprotection;

2013
Licorice treatment prevents oxidative stress, restores cardiac function, and salvages myocardium in rat model of myocardial injury.
    Toxicology and industrial health, 2015, Volume: 31, Issue:2

    Topics: Animals; Glycyrrhiza; Heart; Hemodynamics; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infar

2015
Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Animals; Apoptosis; bcl-X Protein; Cytochromes c; G-Protein-Coupled Receptor Kinase 2; Hemodynamics;

2013
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium.
    British journal of pharmacology, 2013, Volume: 170, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2013
Antioxidant activity of ethanolic extract of Terminalia chebula fruit against isoproterenol-induced oxidative stress in rats.
    Indian journal of biochemistry & biophysics, 2005, Volume: 42, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Ceruloplasmin; Ethanol; Fruit; Glutathione; Heart; Iron; Isopr

2005
Regulation of antioxidant system, lipids and fatty acid β-oxidation contributes to the cardioprotective effect of sodium tanshinone IIA sulphonate in isoproterenol-induced myocardial infarction in rats.
    Atherosclerosis, 2013, Volume: 230, Issue:1

    Topics: Animals; Antioxidants; Cardiotonic Agents; Disease Models, Animal; Fatty Acids; Gene Expression Regu

2013
Reduction of coenzyme q10 content: a possible effect of isoproterenol on heart failure and myocardial infarction in rat.
    Drug research, 2014, Volume: 64, Issue:4

    Topics: Animals; Heart Failure; Hemodynamics; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction

2014
Diosmin exhibits anti-hyperlipidemic effects in isoproterenol induced myocardial infarcted rats.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Animals; Biomarkers; Diosmin; Heart Ventricles; Hypolipidemic Agents; Isoproterenol; Lipid Metabolis

2013
The metabolic disturbances of isoproterenol induced myocardial infarction in rats based on a tissue targeted metabonomics.
    Molecular bioSystems, 2013, Volume: 9, Issue:11

    Topics: Animals; Biomarkers; Disease Models, Animal; Isoproterenol; Male; Mass Spectrometry; Metabolic Netwo

2013
Cardioprotective effect of methanolic extract of Marrubium vulgare L. on isoproterenol-induced acute myocardial infarction in rats.
    Indian journal of experimental biology, 2013, Volume: 51, Issue:8

    Topics: Animals; Antioxidants; Cardiotonic Agents; Electrocardiography; Heart; Isoproterenol; Lipid Peroxida

2013
[Effects of the umbilical blood stem cells in experimental injury of myocardium].
    Klinichna khirurhiia, 2013, Issue:7

    Topics: Animals; Cord Blood Stem Cell Transplantation; Cryopreservation; Female; Fetal Blood; Humans; Isopro

2013
Metabolic pathways involved in Xin-Ke-Shu protecting against myocardial infarction in rats using ultra high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 90

    Topics: Administration, Oral; Animals; Biomarkers; Cardiotonic Agents; Chromatography, High Pressure Liquid;

2014
Eugenia jambolana pretreatment prevents isoproterenol-induced myocardial damage in rats: evidence from biochemical, molecular, and histopathological studies.
    Journal of medicinal food, 2014, Volume: 17, Issue:2

    Topics: Animals; Biomarkers; C-Reactive Protein; Glutathione; Heart; Humans; Isoproterenol; Male; Malondiald

2014
Preventive effects of selenium yeast, chromium picolinate, zinc sulfate and their combination on oxidative stress, inflammation, impaired angiogenesis and atherogenesis in myocardial infarction in rats.
    Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2013, Volume: 16, Issue:5

    Topics: Animals; Atherosclerosis; Cardiotonic Agents; Drug Therapy, Combination; Dyslipidemias; Inflammation

2013
Cardioprotective effect of rhizomes of Acorus gramineus against isoproterenol-induced cardiac damage in pigs.
    Cardiovascular toxicology, 2014, Volume: 14, Issue:2

    Topics: Acorus; Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Cytoprotection; Disease Models, Anima

2014
Effects of LDL and oxidized LDL on cardiac function in isoproterenol-induced myocardial infarction in rat.
    Drug research, 2014, Volume: 64, Issue:11

    Topics: Animals; Cholesterol, Dietary; Electrocardiography; Hemodynamics; Isoproterenol; Lipid Peroxidation;

2014
Cardioprotective effect of mumie (shilajit) on experimentally induced myocardial injury.
    Cardiovascular toxicology, 2014, Volume: 14, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Heart

2014
Red ginseng (Panax ginseng) decreases isoproterenol-induced cardiac injury via antioxidant properties in porcine.
    Journal of medicinal food, 2014, Volume: 17, Issue:1

    Topics: Animals; Antioxidants; Ginsenosides; Humans; Isoproterenol; Male; Malondialdehyde; Myocardial Infarc

2014
Isoproterenol‑mediated heme oxygenase‑1 induction inhibits high mobility group box 1 protein release and protects against rat myocardial ischemia/reperfusion injury in vivo.
    Molecular medicine reports, 2014, Volume: 9, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Creatine Kinase; Disease Models, Animal; Heme Oxygenase-1; Hemody

2014
Soluble epoxide hydrolase inhibitor, t-TUCB, protects against myocardial ischaemic injury in rats.
    The Journal of pharmacy and pharmacology, 2014, Volume: 66, Issue:9

    Topics: Animals; Antioxidants; Benzoates; Biomarkers; Cardiotonic Agents; Epoxide Hydrolases; Heart; Heart C

2014
[The influence of dietary omega-3 polyunsaturated fatty acids on functional parameters of myocardial mitochondria during isoproterenol-induced heart injury].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2014, Volume: 60, Issue:1

    Topics: Administration, Oral; Animals; Calcium; Disease Models, Animal; Fatty Acids, Omega-3; Isoproterenol;

2014
Cardioprotective effect of embelin on isoproterenol-induced myocardial injury in rats: possible involvement of mitochondrial dysfunction and apoptosis.
    Life sciences, 2014, Jun-27, Volume: 107, Issue:1-2

    Topics: Animals; Antioxidants; Apoptosis; Benzoquinones; Biomarkers; Blotting, Western; Cardiotonic Agents;

2014
Chronic treatment with metformin suppresses toll-like receptor 4 signaling and attenuates left ventricular dysfunction following myocardial infarction.
    European journal of pharmacology, 2014, Aug-15, Volume: 737

    Topics: AMP-Activated Protein Kinases; Animals; Hemodynamics; Interleukin-6; Isoproterenol; Male; Metformin;

2014
Effects of carnosine on prooxidant-antioxidant status in heart tissue, plasma and erythrocytes of rats with isoproterenol-induced myocardial infarction.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:1

    Topics: Animals; Carnosine; Erythrocytes; Glutathione Peroxidase; Isoproterenol; Lipid Peroxidation; Male; M

2014
Elevated adropin: a candidate diagnostic marker for myocardial infarction in conjunction with troponin-I.
    Peptides, 2014, Volume: 58

    Topics: Adrenergic beta-Agonists; Animals; Biomarkers; Blood Proteins; Isoproterenol; Myocardial Infarction;

2014
Can early myocardial infarction-related deaths be diagnosed using postmortem urotensin receptor expression levels?
    Forensic science, medicine, and pathology, 2014, Volume: 10, Issue:3

    Topics: Animals; Autopsy; Biomarkers; Disease Models, Animal; Forensic Genetics; Isoproterenol; Male; Myocar

2014
Hesperidin blunts streptozotocin-isoproternol induced myocardial toxicity in rats by altering of PPAR-γ receptor.
    Chemico-biological interactions, 2014, Aug-05, Volume: 219

    Topics: Anilides; Animals; Catalase; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Female; Glut

2014
Cardiac sympathetic afferent denervation attenuates cardiac remodeling and improves cardiovascular dysfunction in rats with heart failure.
    Hypertension (Dallas, Tex. : 1979), 2014, Volume: 64, Issue:4

    Topics: Adrenergic beta-Agonists; Afferent Pathways; Animals; Apoptosis; Blotting, Western; Cardiomegaly; Ca

2014
Interleukin-1β blockade improves left ventricular systolic/diastolic function and restores contractility reserve in severe ischemic cardiomyopathy in the mouse.
    Journal of cardiovascular pharmacology, 2014, Volume: 64, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Disease Models, Animal; Echocardiography; Interleukin-1beta; Isopro

2014
The effect of caffeic acid phenethyl ester on isoproterenol-induced myocardial injury in hypertensive rats.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2014, Volume: 14, Issue:7

    Topics: Animals; Antioxidants; Blood Pressure; Caffeic Acids; Disease Models, Animal; Hypertension; Injectio

2014
Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats.
    Human & experimental toxicology, 2015, Volume: 34, Issue:5

    Topics: Animals; Apoptosis; Betaine; Biomarkers; Cardiotonic Agents; Dose-Response Relationship, Drug; Isopr

2015
Pre-treatment with α-tocopherol and Terminalia arjuna ameliorates, pro-inflammatory cytokines, cardiac and apoptotic markers in myocardial infracted rats.
    Redox report : communications in free radical research, 2015, Volume: 20, Issue:2

    Topics: alpha-Tocopherol; Animals; Apoptosis; bcl-2-Associated X Protein; Cardiotonic Agents; Chromatography

2015
The plant histaminase: a promising enzyme with antioxidant properties versus histamine release in isoprenaline-induced myocardial infarction in rats.
    Journal of physiology and biochemistry, 2014, Volume: 70, Issue:3

    Topics: Amine Oxidase (Copper-Containing); Animals; Antioxidants; Cardiotonic Agents; Catalase; Creatine Kin

2014
Assessment of the prophylactic role of aspirin and/or clopidogrel on experimentally induced acute myocardial infarction in hypercholesterolemic rats.
    Drugs in R&D, 2014, Volume: 14, Issue:4

    Topics: Animals; Aspirin; C-Reactive Protein; Cholesterol; Clopidogrel; Creatine Kinase; Diet, High-Fat; Dru

2014
Beneficial role of tamoxifen in isoproterenol-induced myocardial infarction.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:10

    Topics: Adrenergic beta-Agonists; Animals; Collagen; Female; Heart Ventricles; Hemodynamics; Isoproterenol;

2014
Benidipine prevents oxidative stress, inflammatory changes and apoptosis related myofibril damage in isoproterenol-induced myocardial infarction in rats.
    Toxicology mechanisms and methods, 2015, Volume: 25, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Biomarkers; Cytoprotection; Dihydropyrid

2015
Preventive effects of zingerone on altered lipid peroxides and nonenzymatic antioxidants in the circulation of isoproterenol-induced myocardial infarcted rats.
    Journal of biochemical and molecular toxicology, 2015, Volume: 29, Issue:2

    Topics: Animals; Antioxidants; Cardiotonic Agents; Guaiacol; Isoproterenol; Lipid Peroxidation; Male; Myocar

2015
Tacrolimus ameliorates functional disturbances and oxidative stress in isoproterenol-induced myocardial infarction.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2014, Oct-14, Volume: 22

    Topics: Administration, Cutaneous; Animals; Disease Models, Animal; Drug Administration Schedule; Electrocar

2014
Quantitative proteomics for cardiac biomarker discovery using isoproterenol-treated nonhuman primates.
    Journal of proteome research, 2014, Dec-05, Volume: 13, Issue:12

    Topics: Animals; Biomarkers; Female; Isoproterenol; Macaca fascicularis; Macaca mulatta; Male; Muscle Protei

2014
A biochemical and 2, 3, 5-triphenyl tetrazolium chloride staining study on the preventive effects of zingerone (vanillyl acetone) in experimentally induced myocardial infarcted rats.
    European journal of pharmacology, 2015, Jan-05, Volume: 746

    Topics: Adenosine Triphosphatases; Animals; Biomarkers; Coloring Agents; Disease Models, Animal; Electrocard

2015
Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats.
    Heart, lung & circulation, 2015, Volume: 24, Issue:6

    Topics: Analysis of Variance; Animals; Biomarkers; Biopsy, Needle; Cardiotonic Agents; Cytokines; Disease Mo

2015
Antihyperlipidaemic, antihypertrophic, and reducing effects of zingerone on experimentally induced myocardial infarcted rats.
    Journal of biochemical and molecular toxicology, 2015, Volume: 29, Issue:4

    Topics: Animals; Cardiomegaly; Guaiacol; Hyperlipidemias; Hypolipidemic Agents; Isoproterenol; Male; Myocard

2015
Preventive effect of phytic acid on lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats.
    Toxicology mechanisms and methods, 2015, Volume: 25, Issue:2

    Topics: Acetylglucosaminidase; Animals; Antioxidants; Cathepsin B; Cathepsin D; Cytoprotection; Disease Mode

2015
Comparison of Cardiomyocyte Differentiation Potential Between Type 1 Diabetic Donor- and Nondiabetic Donor-Derived Induced Pluripotent Stem Cells.
    Cell transplantation, 2015, Volume: 24, Issue:12

    Topics: Action Potentials; Adrenergic beta-Agonists; Biomarkers; Cell Differentiation; Cell- and Tissue-Base

2015
Enhanced β-adrenergic cardiac reserve in Trpm4⁻/⁻ mice with ischaemic heart failure.
    Cardiovascular research, 2015, Mar-01, Volume: 105, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Electrocardiography; Heart Failure; Hypertrophy, Left Ventricular

2015
SERCA-2a is involved in the right ventricular function following myocardial infarction in rats.
    Life sciences, 2015, Mar-01, Volume: 124

    Topics: Animals; Disease Models, Animal; Gene Expression Regulation; Heart Failure; Isometric Contraction; I

2015
Superiority of zinc complex of acetylsalicylic acid to acetylsalicylic acid in preventing postischemic myocardial dysfunction.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coordination Complexes; Electrocardiograp

2015
β-Adrenergic stimulation and rapid pacing mutually promote heterogeneous electrical failure and ventricular fibrillation in the globally ischemic heart.
    American journal of physiology. Heart and circulatory physiology, 2015, May-01, Volume: 308, Issue:9

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Cardiac Pacing, Artificial; Death, Sudden, Car

2015
Thymol attenuates inflammation in isoproterenol induced myocardial infarcted rats by inhibiting the release of lysosomal enzymes and downregulating the expressions of proinflammatory cytokines.
    European journal of pharmacology, 2015, May-05, Volume: 754

    Topics: Animals; Anti-Inflammatory Agents; C-Reactive Protein; Cytokines; Down-Regulation; Electrocardiograp

2015
Adipose stem cell sheets improved cardiac function in the rat myocardial infarction, but did not alter cardiac contractile responses to β-adrenergic stimulation.
    Biomedical research (Tokyo, Japan), 2015, Volume: 36, Issue:1

    Topics: Adipocytes; Animals; Atrial Natriuretic Factor; Atrial Remodeling; Bucladesine; Cardiomegaly; Cell D

2015
Dietary Chitosan Supplementation Ameliorates Isoproterenol-Induced Aberrations in Membrane-Bound ATPases and Mineral Status of Rat Myocardium.
    Biological trace element research, 2015, Volume: 167, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Calcium; Cardiotonic Agents; Cell Membrane; Chitosan; Dietary Su

2015
Racing to the flatline: heart rate and β-adrenergic stimulation quicken the pace.
    American journal of physiology. Heart and circulatory physiology, 2015, May-01, Volume: 308, Issue:9

    Topics: Adrenergic beta-Agonists; Animals; Cardiac Pacing, Artificial; Female; Heart Conduction System; Hear

2015
Protective effects of Labisia pumila var. alata on biochemical and histopathological alterations of cardiac muscle cells in isoproterenol-induced myocardial infarction rats.
    Molecules (Basel, Switzerland), 2015, Mar-16, Volume: 20, Issue:3

    Topics: Administration, Oral; Animals; Cardiotonic Agents; Cell Membrane; Disease Models, Animal; Dose-Respo

2015
Histone deacetylase inhibition enhances tissue plasminogen activator release capacity in atherosclerotic man.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Aged; Female; Forearm; Histone Deacetylase Inhibitors; Humans; Isoproterenol; Male; Middle Aged; Myo

2015
Protective Effect of Hydroxytyrosol Against Cardiac Remodeling After Isoproterenol-Induced Myocardial Infarction in Rat.
    Cardiovascular toxicology, 2016, Volume: 16, Issue:2

    Topics: Animals; Cardiotonic Agents; Isoproterenol; Male; Myocardial Infarction; Phenylethyl Alcohol; Rats;

2016
Protective effects of the standardized extract of Zingiber officinale on myocardium against isoproterenol-induced biochemical and histopathological alterations in rats.
    Pharmaceutical biology, 2015, Volume: 53, Issue:12

    Topics: Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Isoproterenol; Male; Myocardial Infar

2015
Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence.
    Redox report : communications in free radical research, 2015, Volume: 20, Issue:6

    Topics: Animals; Antioxidants; Antipyrine; Apoptosis; C-Reactive Protein; Caspase 3; Creatine Kinase, MB For

2015
Cardioprotective effect of linseed oil against isoproterenol-induced myocardial infarction in Wistar rats: a biochemical and electrocardiographic study.
    Journal of physiology and biochemistry, 2015, Volume: 71, Issue:2

    Topics: Animals; Body Weight; Cardiotonic Agents; Electrocardiography; Enzymes; Fatty Acids; Flax; Isoproter

2015
Preventive effects of oleuropein against cardiac remodeling after myocardial infarction in Wistar rat through inhibiting angiotensin-converting enzyme activity.
    Toxicology mechanisms and methods, 2015, Volume: 25, Issue:7

    Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relations

2015
Cardioprotective Effects of Tualang Honey: Amelioration of Cholesterol and Cardiac Enzymes Levels.
    BioMed research international, 2015, Volume: 2015

    Topics: Animals; Antioxidants; Aspartate Aminotransferases; Cardiotonic Agents; Cholesterol; Creatine Kinase

2015
Comparative evaluation of HMG CoA reductase inhibitors in experimentally-induced myocardial necrosis: Biochemical, morphological and histological studies.
    European journal of pharmacology, 2015, Oct-05, Volume: 764

    Topics: Adenosine Triphosphatases; Animals; Atorvastatin; Blood Glucose; Cardiotonic Agents; Catalase; Chole

2015
Apigenin Attenuates β-Receptor-Stimulated Myocardial Injury Via Safeguarding Cardiac Functions and Escalation of Antioxidant Defence System.
    Cardiovascular toxicology, 2016, Volume: 16, Issue:3

    Topics: Animals; Antioxidants; Apigenin; Biomarkers; Catalase; Creatine Kinase, MB Form; Cytoprotection; Dis

2016
Protective effect of a polysaccharide from Salvia miltiorrhiza on isoproterenol (ISO)-induced myocardial injury in rats.
    Carbohydrate polymers, 2015, Nov-05, Volume: 132

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Cardiotonic Agents; Creati

2015
Plant Natural Products Calycosin and Gallic Acid Synergistically Attenuate Neutrophil Infiltration and Subsequent Injury in Isoproterenol-Induced Myocardial Infarction: A Possible Role for Leukotriene B4 12-Hydroxydehydrogenase?
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Alcohol Oxidoreductases; Animals; Astragalus Plant; Biological Products; Cell Survival; Chromatograp

2015
Cardioprotective effects of timosaponin B II from Anemarrhenae asphodeloides Bge on isoproterenol-induced myocardial infarction in rats.
    Chemico-biological interactions, 2015, Oct-05, Volume: 240

    Topics: Anemarrhena; Animals; Biomarkers; Blotting, Western; Cardiotonic Agents; Disease Models, Animal; Iso

2015
Anti-inflammatory, Antithrombotic and Cardiac Remodeling Preventive Effects of Eugenol in Isoproterenol-Induced Myocardial Infarction in Wistar Rat.
    Cardiovascular toxicology, 2016, Volume: 16, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarker

2016
Anti-platelet effects of nimesulide in isoproterenol-induced myocardial ischaemia and infarction in rabbits.
    Acta cardiologica, 2015, Volume: 70, Issue:4

    Topics: Animals; Disease Models, Animal; Isoproterenol; Myocardial Infarction; Platelet Activating Factor; P

2015
The effects of Melissa officinalis (lemon balm) pretreatment on the resistance of the heart to myocardial injury.
    Pharmaceutical biology, 2016, Volume: 54, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Heart Rate; Isoproterenol; Male; Melissa; Myocardial Infa

2016
Amelioration of Isoproterenol-Induced Oxidative Damage in Rat Myocardium by Withania somnifera Leaf Extract.
    BioMed research international, 2015, Volume: 2015

    Topics: Animals; Antioxidants; Biomarkers; Glutathione Peroxidase; Humans; Isoproterenol; Lipid Peroxidation

2015
Protective Effects of Cardamom in Isoproterenol-Induced Myocardial Infarction in Rats.
    International journal of molecular sciences, 2015, Nov-17, Volume: 16, Issue:11

    Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Catalase; Creatine Kinase, MB Form; Disease M

2015
Bone marrow mononuclear cells enhance anti-inflammatory effects of pravastatin against isoproterenol-induced myocardial infarction in rats.
    Journal of immunotoxicology, 2016, Volume: 13, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Bone Marrow Cells; Combined Modality Therapy; Cytokine

2016
Baicalin ameliorates isoproterenol-induced acute myocardial infarction through iNOS, inflammation and oxidative stress in rat.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:9

    Topics: Animals; Apoptosis; Casein Kinases; Caspase 3; Creatine Kinase, MB Form; Enzyme Inhibitors; Flavonoi

2015
[The Action of Apelin-12 and Its Analog on Hemodynamics and Cardiac Contractile Function of Rats With Isoproterenol-Induced Myocardial Lesion].
    Kardiologiia, 2015, Volume: 55, Issue:6

    Topics: Animals; Disease Models, Animal; Hemodynamics; Intercellular Signaling Peptides and Proteins; Isopro

2015
Amelioration of inflammation by phenolic rich methanolic extract of Ocimum sanctum Linn. leaves in isoproterenol induced myocardial infarction.
    Indian journal of experimental biology, 2015, Volume: 53, Issue:10

    Topics: Animals; Antioxidants; Disease Models, Animal; Inflammation; Isoproterenol; Leukotriene B4; Male; Me

2015
Thymol, a dietary monoterpene phenol abrogates mitochondrial dysfunction in β-adrenergic agonist induced myocardial infarcted rats by inhibiting oxidative stress.
    Chemico-biological interactions, 2016, Jan-25, Volume: 244

    Topics: Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; Injections, Subcutaneous; Isopr

2016
Molecular and biochemical evidence on the protective effects of embelin and carnosic acid in isoproterenol-induced acute myocardial injury in rats.
    Life sciences, 2016, Feb-15, Volume: 147

    Topics: Abietanes; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Benzoquinones; Cardiotonic Ag

2016
Effect of exercise training and myocardial infarction on force development and contractile kinetics in isolated canine myocardium.
    Journal of applied physiology (Bethesda, Md. : 1985), 2016, Apr-15, Volume: 120, Issue:8

    Topics: Adrenergic beta-Agonists; Animals; Dogs; Heart; Heart Ventricles; Isoproterenol; Kinetics; Myocardia

2016
Edaravone, a potent free radical scavenger and a calcium channel blocker attenuate isoproterenol induced myocardial infarction by suppressing oxidative stress, apoptotic signaling and ultrastructural damage.
    Therapeutic advances in cardiovascular disease, 2016, Volume: 10, Issue:4

    Topics: Animals; Antipyrine; Apoptosis; C-Reactive Protein; Calcium Channel Blockers; Caspase 3; Dihydropyri

2016
Protective Effect of Adansonia digitata against Isoproterenol-Induced Myocardial Injury in Rats.
    Animal biotechnology, 2016, Volume: 27, Issue:2

    Topics: Adansonia; Animals; Antioxidants; Female; Fruit; Heart; Isoproterenol; Myocardial Infarction; Myocar

2016
Activation of β1-adrenoceptor triggers oxidative stress mediated myocardial membrane destabilization in isoproterenol induced myocardial infarcted rats: 7-hydroxycoumarin and its counter action.
    European journal of pharmacology, 2016, Apr-15, Volume: 777

    Topics: Adenosine Triphosphatases; Animals; Cell Membrane; Dose-Response Relationship, Drug; Isoproterenol;

2016
Protective Effects of 7-Hydroxycoumarin on Dyslipidemia and Cardiac Hypertrophy in Isoproterenol-Induced Myocardial Infarction in Rats.
    Journal of biochemical and molecular toxicology, 2016, Volume: 30, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Cardiomegaly; Dyslipidemias; Hydroxymethylglutaryl CoA Reductases

2016
Histamine H3 Receptor Agonist Imetit Attenuated Isoproterenol Induced Renin Angiotensin System and Sympathetic Nervous System Overactivity in Myocardial Infarction of Rats.
    Drug research, 2016, Volume: 66, Issue:6

    Topics: Angiotensin II; Animals; Antioxidants; Cardiotonic Agents; Histamine Agonists; Histamine H3 Antagoni

2016
Paeonol and danshensu combination attenuates apoptosis in myocardial infarcted rats by inhibiting oxidative stress: Roles of Nrf2/HO-1 and PI3K/Akt pathway.
    Scientific reports, 2016, Mar-29, Volume: 6

    Topics: Acetophenones; Animals; Apoptosis; Blotting, Western; Cardiotonic Agents; Creatine Kinase, MB Form;

2016
Dietary Phenolic Acids of Macrotyloma uniflorum (Horse Gram) Protect the Rat Heart Against Isoproterenol-Induced Myocardial Infarction.
    Phytotherapy research : PTR, 2016, Volume: 30, Issue:7

    Topics: Animals; Antioxidants; Fabaceae; Heart; Hydroxybenzoates; Isoproterenol; Male; Myocardial Infarction

2016
Cardioprotective effect of pioglitazone in diabetic and non-diabetic rats subjected to acute myocardial infarction involves suppression of AGE-RAGE axis and inhibition of apoptosis.
    Canadian journal of physiology and pharmacology, 2016, Volume: 94, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Cardiotonic Agents; Diabetes Mellitus, Type 2; Diabeti

2016
Chronic oral administration of low-dose combination of fenofibrate and rosuvastatin protects the rat heart against experimentally induced acute myocardial infarction.
    Fundamental & clinical pharmacology, 2016, Volume: 30, Issue:5

    Topics: Administration, Oral; Animals; Cardiotonic Agents; Drug Administration Schedule; Drug Therapy, Combi

2016
Cardioprotective effect of resveratrol analogue isorhapontigenin versus omega-3 fatty acids in isoproterenol-induced myocardial infarction in rats.
    Journal of physiology and biochemistry, 2016, Volume: 72, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Cardiotonic Agents; Diet

2016
Mechanisms underlying the cardioprotective effect of Salvianic acid A against isoproterenol-induced myocardial ischemia injury in rats: Possible involvement of L-type calcium channels and myocardial contractility.
    Journal of ethnopharmacology, 2016, Aug-02, Volume: 189

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; C

2016
Renal denervation improves cardiac function in rats with chronic heart failure: Effects on expression of β-adrenoceptors.
    American journal of physiology. Heart and circulatory physiology, 2016, 08-01, Volume: 311, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Chronic Disease; Collagen Type I; Coronary Vessels; Heart; Heart

2016
Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats.
    BioMed research international, 2016, Volume: 2016

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Body Weight; Creatine Kina

2016
Standardized Chinese Formula Xin-Ke-Shu inhibits the myocardium Ca(2+) overloading and metabolic alternations in isoproterenol-induced myocardial infarction rats.
    Scientific reports, 2016, 07-26, Volume: 6

    Topics: Animals; Biomarkers; Calcium; Drugs, Chinese Herbal; Heart; Isoproterenol; Male; Medicine, Chinese T

2016
Molecular and biochemical evidence on the protective effects of quercetin in isoproterenol-induced acute myocardial injury in rats.
    Journal of biochemical and molecular toxicology, 2017, Volume: 31, Issue:1

    Topics: Animals; Calpain; Cardiotonic Agents; Gene Expression Regulation, Enzymologic; Isoproterenol; Male;

2017
Inhibition of RhoA/Rho kinase by ibuprofen exerts cardioprotective effect on isoproterenol induced myocardial infarction in rats.
    European journal of pharmacology, 2016, Nov-15, Volume: 791

    Topics: Animals; Antioxidants; Cardiotonic Agents; Electrocardiography; Gene Expression Regulation, Enzymolo

2016
Anti-inflammatory and anti-thrombotic effects of zingerone in a rat model of myocardial infarction.
    European journal of pharmacology, 2016, Nov-15, Volume: 791

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Disease Models, Animal; Fibrinolytic Agents; Glyceral

2016
Chlorogenic acid a dietary polyphenol attenuates isoproterenol induced myocardial oxidative stress in rat myocardium: An in vivo study.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Animals; Antioxidants; Biomarkers; Chlorogenic Acid; Disease Models, Animal; Dose-Response Relations

2016
Impact of cardiac-specific expression of CD39 on myocardial infarct size in mice.
    Life sciences, 2017, Jun-15, Volume: 179

    Topics: Animals; Antigens, CD; Apyrase; Calcium; Disease Models, Animal; Echocardiography; Gene Expression;

2017
Kampeferol protects against oxidative stress and apoptotic damage in experimental model of isoproterenol-induced cardiac toxicity in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Nov-15, Volume: 23, Issue:12

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cardiotoxicity; Catalase; Glutathione; Heart; Interleu

2016
Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction.
    Circulation research, 2017, Jan-06, Volume: 120, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Catecholamines; Cyclic Nucleotide Phosphodiestera

2017
Epigallocatechin-3-gallate prevents cardiac apoptosis by modulating the intrinsic apoptotic pathway in isoproterenol-induced myocardial infarction.
    European journal of pharmacology, 2017, Jan-05, Volume: 794

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Body Weight; Catechin; Cytoprotection; Isoproterenol;

2017
Piperine modulates isoproterenol induced myocardial ischemia through antioxidant and anti-dyslipidemic effect in male Wistar rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 87

    Topics: Alkaloids; Animals; Antioxidants; Benzodioxoles; Biomarkers; Heart; Isoproterenol; Lipid Peroxidatio

2017
Effect of vitamin D on isoprenaline-induced myocardial infarction in rats: possible role of peroxisome proliferator-activated receptor-γ.
    Canadian journal of physiology and pharmacology, 2017, Volume: 95, Issue:6

    Topics: Animals; Biomarkers; Electrocardiography; Isoproterenol; Male; Myocardial Infarction; Oxidative Stre

2017
Cardioprotective activity of Ginkgo biloba Phytosomes in isoproterenol-induced myocardial necrosis in rats: a biochemical and histoarchitectural evaluation.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2008, Volume: 60, Issue:4-5

    Topics: Adrenergic beta-Agonists; Animals; Ginkgo biloba; Heart; Isoproterenol; Myocardial Infarction; Myoca

2008
(-)Epigallocatechingallate protects the mitochondria against the deleterious effects of lipids, calcium and adenosine triphosphate in isoproterenol induced myocardial infarcted male Wistar rats.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:8

    Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium; Catechin; Cholesterol; Fatty Aci

2008
Cardioprotective effect of 'Marutham' a polyherbal formulation on isoproterenol induced myocardial infarction in Wistar rats.
    Fitoterapia, 2008, Volume: 79, Issue:6

    Topics: Animals; Cardiotonic Agents; Hyperlipidemias; Isoproterenol; Lipids; Lipoproteins; Male; Membrane Pr

2008
Combined transplantation of endothelial progenitor cells and mesenchymal stem cells into a rat model of isoproterenol-induced myocardial injury.
    Archives of cardiovascular diseases, 2008, Volume: 101, Issue:5

    Topics: Angiopoietin-2; Animals; Cardiotonic Agents; Disease Models, Animal; Endothelium, Vascular; Female;

2008
Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions.
    Journal of pineal research, 2008, Volume: 45, Issue:4

    Topics: Adrenergic Antagonists; Animals; Colforsin; Cyclic AMP; Guanylate Cyclase; Heart; Indoles; Isoproter

2008
Cardioprotective effect of aqueous extract of Embelia ribes Burm fruits against isoproterenol-induced myocardial infarction in albino rats.
    Indian journal of experimental biology, 2008, Volume: 46, Issue:1

    Topics: Animals; Antioxidants; Blood Pressure; Embelia; Flavonoids; Glutathione; Hemodynamics; Isoproterenol

2008
Protective effect of aspartate and glutamate on cardiac mitochondrial function during myocardial infarction in experimental rats.
    Chemico-biological interactions, 2008, Nov-25, Volume: 176, Issue:2-3

    Topics: Animals; Aspartic Acid; Disease Models, Animal; Enzyme Activation; Glutamic Acid; Glutathione; Gluta

2008
Naringin ameliorates mitochondrial lipid peroxides, antioxidants and lipids in isoproterenol-induced myocardial infarction in Wistar rats.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:3

    Topics: Animals; Antioxidants; Cardiotonic Agents; Disease Models, Animal; Flavanones; Isoproterenol; Lipid

2009
Effect of Commiphora mukul extract on cardiac dysfunction and ventricular function in isoproterenol-induced myocardial infarction.
    Indian journal of experimental biology, 2008, Volume: 46, Issue:9

    Topics: Animals; Blood Pressure; Commiphora; Isoproterenol; Male; Myocardial Infarction; Plant Extracts; Rat

2008
Effect of green tea and vitamin E combination in isoproterenol induced myocardial infarction in rats.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2009, Volume: 64, Issue:1

    Topics: Adenosine Triphosphatases; Analysis of Variance; Animals; Antioxidants; Drug Synergism; Isoprotereno

2009
PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts.
    Journal of molecular and cellular cardiology, 2009, Volume: 46, Issue:4

    Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Dogs; Enzyme Activation; In Vitro Techniques; Isoprot

2009
Preventive effect of S-allylcysteine on membrane-bound enzymes and glycoproteins in normal and isoproterenol-induced cardiac toxicity in male Wistar rats.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:6

    Topics: Adenosine Triphosphatases; alpha-Tocopherol; Animals; Antioxidants; Blood Proteins; Cell Membrane; C

2008
[Expression and implication of angiotensin II type 1 receptor in myocardial fibrosis of rats].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2008, Volume: 37, Issue:10

    Topics: Animals; Aspartate Aminotransferases; Cardiomyopathies; Cell Differentiation; Creatine Kinase; Fibro

2008
Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats.
    Chemico-biological interactions, 2009, May-15, Volume: 179, Issue:2-3

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Cardiotonic Ag

2009
Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation.
    British journal of pharmacology, 2009, Volume: 156, Issue:4

    Topics: Animals; Blood Pressure; Calcium; Carbachol; Cardiac Myosins; Cardiotonic Agents; Disease Models, An

2009
Mechanism of protective action of mangiferin on suppression of inflammatory response and lysosomal instability in rat model of myocardial infarction.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:6

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Hydrolases; Isoproterenol; Lysosomes; Male; Myo

2009
Antilipoperoxidative and membrane stabilizing effect of diosgenin, in experimentally induced myocardial infarction.
    Molecular and cellular biochemistry, 2009, Volume: 327, Issue:1-2

    Topics: Animals; Antioxidants; Cell Membrane; Diosgenin; Hydrolases; Isoproterenol; Lipid Peroxidation; Lyso

2009
Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study.
    Molecular and cellular biochemistry, 2009, Volume: 328, Issue:1-2

    Topics: Animals; Cysteine; Isoproterenol; Male; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins

2009
Antioxidant defense of betaine against isoprenaline-induced myocardial infarction in rats.
    Molecular biology reports, 2010, Volume: 37, Issue:3

    Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Aspartate Aminotransferases; Beta

2010
Protective effect of betaine on changes in the levels of lysosomal enzyme activities in heart tissue in isoprenaline-induced myocardial infarction in Wistar rats.
    Cell stress & chaperones, 2009, Volume: 14, Issue:6

    Topics: Acid Phosphatase; Animals; Betaine; Cardiotonic Agents; Enzyme Activation; Glycoside Hydrolases; Hea

2009
Investigation of effects of Lacidipine, Ramipril and Valsartan on DNA damage and oxidative stress occurred in acute and chronic periods following isoproterenol-induced myocardial infarct in rats.
    Molecular and cellular biochemistry, 2009, Volume: 328, Issue:1-2

    Topics: Animals; Antihypertensive Agents; Biomarkers; Dihydropyridines; DNA Damage; Guanine; Isoproterenol;

2009
Moringa oleifera leaf extract prevents isoproterenol-induced myocardial damage in rats: evidence for an antioxidant, antiperoxidative, and cardioprotective intervention.
    Journal of medicinal food, 2009, Volume: 12, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Blood Pressure; Heart; Heart Rate; Isoproterenol; L

2009
Cardioprotective potential of myricetin in isoproterenol-induced myocardial infarction in Wistar rats.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:10

    Topics: Animals; Aspartate Aminotransferases; Biomarkers; Catalase; Creatine Kinase; Disease Models, Animal;

2009
Effects of Muntingia calabura L. on isoproterenol-induced myocardial infarction.
    Singapore medical journal, 2009, Volume: 50, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Case-Control Studies; Herbal Medicine; H

2009
Protective effect of betaine on changes in the levels of membrane-bound ATPase activity and mineral status in experimentally induced myocardial infarction in Wistar rats.
    Biological trace element research, 2009, Volume: 131, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Betaine; Calcium; Cardiotonic Agents; Isoproterenol; Lipid Perox

2009
Oestrogen confers cardioprotection by suppressing Ca2+/calmodulin-dependent protein kinase II.
    British journal of pharmacology, 2009, Volume: 157, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Benzylamines; Calcium Signaling; Calcium-Calmodulin-De

2009
Cardioprotective effect of salvianolic acid A on isoproterenol-induced myocardial infarction in rats.
    European journal of pharmacology, 2009, Aug-01, Volume: 615, Issue:1-3

    Topics: Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Caffeic Acids; Cardiotonic Agents; C

2009
Gallic acid prevents lysosomal damage in isoproterenol induced cardiotoxicity in Wistar rats.
    European journal of pharmacology, 2009, Aug-01, Volume: 615, Issue:1-3

    Topics: Acetylglucosaminidase; Adrenergic beta-Agonists; Animals; Antioxidants; beta-Galactosidase; Biomarke

2009
Ascorbic acid prevents acute myocardial infarction induced by isoproterenol in rats: role of inducible nitric oxide synthase production.
    Journal of molecular histology, 2009, Volume: 40, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Cyclooxygenase 2; Immunohistochemistry; Isoproterenol; Male; M

2009
Cardioprotective actions of ascorbic acid during isoproterenol-induced acute myocardial infarction in rats.
    Pharmacology, 2009, Volume: 84, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Do

2009
Role of Sida cordifolia L. leaves on biochemical and antioxidant profile during myocardial injury.
    Journal of ethnopharmacology, 2009, Jul-06, Volume: 124, Issue:1

    Topics: Animals; Antioxidants; Catalase; Creatine Kinase, MB Form; Heart; Isoproterenol; L-Lactate Dehydroge

2009
Metabolomic profiling of rat serum associated with isoproterenol-induced myocardial infarction using ultra-performance liquid chromatography/time-of-flight mass spectrometry and multivariate analysis.
    Talanta, 2009, Jul-15, Volume: 79, Issue:2

    Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Isoproterenol; Lipid Metabolism; Lipids;

2009
MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection.
    Cardiovascular research, 2009, Dec-01, Volume: 84, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Cyclic AMP-Dep

2009
Evaluation of cardioprotective activity of Ginkgo biloba and Ocimum sanctum in rodents.
    Alternative medicine review : a journal of clinical therapeutic, 2009, Volume: 14, Issue:2

    Topics: Animals; Antioxidants; Cardiotonic Agents; Dose-Response Relationship, Drug; Ginkgo biloba; Isoprote

2009
Combined effects of quercetin and alpha-tocopherol on lipids and glycoprotein components in isoproterenol induced myocardial infarcted Wistar rats.
    Chemico-biological interactions, 2009, Oct-30, Volume: 181, Issue:3

    Topics: alpha-Tocopherol; Animals; Glycoproteins; Isoproterenol; Lipid Metabolism; Male; Myocardial Infarcti

2009
Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:4

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Animals; Apoptosis; Calcium-Calmoduli

2009
Myocardial salvaging effect of telmisartan in experimental model of myocardial infarction.
    European journal of pharmacology, 2009, Oct-01, Volume: 619, Issue:1-3

    Topics: Animals; Benzimidazoles; Benzoates; Biomarkers; Body Weight; Cardiotonic Agents; Catalase; Disease M

2009
Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury.
    Circulation, 2009, Aug-25, Volume: 120, Issue:8

    Topics: Adrenergic beta-Agonists; Animals; Benzoates; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Cyclooxyge

2009
Exercise training provides cardioprotection via a reduction in reactive oxygen species in rats submitted to myocardial infarction induced by isoproterenol.
    Free radical research, 2009, Volume: 43, Issue:10

    Topics: Animals; Biomarkers; Catalase; Creatine Kinase, MB Form; Disease Models, Animal; Isoproterenol; Male

2009
The phenotype and potential origin of nestin+ cardiac myocyte-like cells following infarction.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Cell Differentiation; Cell Movement; Connexin 43; Disease Models,

2009
Preventive effect of amiodarone during acute period in isoproterenol-induced myocardial injury in Wistar rats.
    Cardiovascular toxicology, 2009, Volume: 9, Issue:4

    Topics: Amiodarone; Animals; Cardiotonic Agents; Disease Models, Animal; Isoproterenol; Male; Myocardial Inf

2009
Preventive effect of low molecular weight glycosaminoglycan from Amussium pleuronectus (Linne) on oxidative injury and cellular abnormalities in isoproterenol-induced cardiotoxicity in Wistar rats.
    Applied biochemistry and biotechnology, 2010, Volume: 162, Issue:1

    Topics: Animals; Antioxidants; Glycosaminoglycans; Heart; Isoproterenol; Male; Molecular Weight; Mollusca; M

2010
Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:3-4

    Topics: Animals; Antioxidants; Carotenoids; Creatine Kinase, MB Form; Crocus; Dose-Response Relationship, Dr

2010
Cardiac biomarkers in a model of acute catecholamine cardiotoxicity.
    Human & experimental toxicology, 2009, Volume: 28, Issue:10

    Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Blood Pressure; Calcium; Catecholamines; Disease M

2009
Isoproterenol induces in vivo functional and metabolic abnormalities: similar to those found in the infarcted rat heart.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Disease Models, Animal; Fatty Acid Transport Prot

2009
Pharmacodynamic interaction of captopril with garlic in isoproterenol-induced myocardial damage in rat.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:5

    Topics: Animals; Captopril; Cardiotonic Agents; Female; Garlic; Herb-Drug Interactions; Isoproterenol; Myoca

2010
Influence of betel quid on effect of calcium channel blockers on isoprenaline induced myocardial necrosis in mice.
    Indian journal of experimental biology, 2009, Volume: 47, Issue:9

    Topics: Animals; Areca; Body Weight; Calcium; Calcium Channel Blockers; Isoproterenol; L-Lactate Dehydrogena

2009
Pretreatment with a combination of quercetin and alpha-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats.
    Life sciences, 2010, Jan-30, Volume: 86, Issue:5-6

    Topics: Adenosine Triphosphatases; alpha-Tocopherol; Animals; Antioxidants; Ca(2+) Mg(2+)-ATPase; Cell Membr

2010
Aspartate and glutamate prevents isoproterenol-induced cardiac toxicity by alleviating oxidative stress in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2011, Volume: 63, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Aspartic Acid; Cardiotonic Agents; Disease Models, An

2011
Protective effect of fish oil on changes in the activities of membrane-bound ATPases and mineral status in experimentally induced myocardial infarction in Wistar rats.
    Biological trace element research, 2010, Volume: 137, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Cardiotonic Agents; Cell Membrane; Fish Oils; Isoproterenol; Lip

2010
Protective effect of caffeic acid on cardiac markers and lipid peroxide metabolism in cardiotoxic rats: an in vivo and in vitro study.
    Metabolism: clinical and experimental, 2010, Volume: 59, Issue:8

    Topics: Animals; Ascorbic Acid; Biomarkers; Caffeic Acids; Isoproterenol; Lipid Peroxidation; Male; Myocardi

2010
Impact of selenium on NFκB translocation in isoproterenol-induced myocardial infarction in rats.
    Biological trace element research, 2010, Volume: 138, Issue:1-3

    Topics: Animals; Antioxidants; Female; Isoproterenol; Myocardial Infarction; NF-kappa B; Oxidative Stress; P

2010
Protective effect of sesamol against myocardial infarction caused by isoproterenol in Wistar rats.
    Redox report : communications in free radical research, 2010, Volume: 15, Issue:1

    Topics: Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Benzodioxol

2010
Melatonin protects against isoproterenol-induced myocardial injury in the rat: antioxidative mechanisms.
    Journal of pineal research, 2010, Volume: 48, Issue:3

    Topics: Animals; Antioxidants; Aspartate Aminotransferases; Blotting, Western; Catalase; Glutathione; Glutat

2010
Caffeic acid protects rat heart mitochondria against isoproterenol-induced oxidative damage.
    Cell stress & chaperones, 2010, Volume: 15, Issue:6

    Topics: Adenosine Triphosphate; Animals; Caffeic Acids; Calcium; Cholesterol; Electron Transport Complex IV;

2010
Cardioprotective effects of aqueous extract of Oxalis corniculata in experimental myocardial infarction.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2011, Volume: 63, Issue:6

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Free Radical Scavengers; Isoproterenol; Magnoli

2011
Pomegranate (Punica granatum L.) juice supplementation attenuates isoproterenol-induced cardiac necrosis in rats.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:3

    Topics: Adenosine Triphosphatases; Adrenergic beta-Agonists; Animals; Antioxidants; Beverages; Creatine Kina

2010
Cardioprotective effect of matrine on isoproterenol-induced cardiotoxicity in rats.
    The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:4

    Topics: Alkaloids; Animals; Antioxidants; Cardiotonic Agents; Drugs, Chinese Herbal; Heart; Isoproterenol; M

2010
Cardioprotective effect of melatonin against isoproterenol induced myocardial infarction in rats: A biochemical, electrocardiographic and histoarchitectural evaluation.
    European journal of pharmacology, 2010, Oct-10, Volume: 644, Issue:1-3

    Topics: Animals; Antioxidants; Cardiotonic Agents; Disease Models, Animal; Electrocardiography; Inflammation

2010
Inhibition of secretory phospholipase A2 activity attenuates acute cardiogenic pulmonary edema induced by isoproterenol infusion in mice after myocardial infarction.
    Journal of cardiovascular pharmacology, 2010, Volume: 56, Issue:4

    Topics: Animals; Indoleacetic Acids; Infusions, Intravenous; Isoproterenol; Leukotriene B4; Lung; Male; Mice

2010
Cardioprotective activity of Cladosiphon okamuranus fucoidan against isoproterenol induced myocardial infarction in rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Dec-15, Volume: 18, Issue:1

    Topics: Animals; Antioxidants; Heart; Isoproterenol; Lipid Peroxidation; Lipids; Male; Myocardial Infarction

2010
Effects of caffeic acid phenethyl ester on isoproterenol-induced myocardial infarction in rats.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2010, Volume: 10, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Aspartate Aminotransferases; Caffeic Acids; Cardiotonic Agents

2010
Drug-disease interaction: reduced verapamil response in isoproterenol-induced myocardial injury in rats.
    Pharmacology, 2010, Volume: 86, Issue:4

    Topics: Animals; Blotting, Western; Calcium Channel Blockers; Calcium Channels, L-Type; Disease Models, Anim

2010
Ramipril-like activity of Spondias mombin linn against no-flow ischemia and isoproterenol-induced cardiotoxicity in rat heart.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:4

    Topics: Anacardiaceae; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Agents; Catalase; C

2010
Flavonoid rich fraction of Dioscorea bulbifera Linn. (Yam) enhances mitochondrial enzymes and antioxidant status and thereby protects heart from isoproterenol induced myocardial infarction.
    Current pharmaceutical biotechnology, 2010, Volume: 11, Issue:8

    Topics: Animals; Antioxidants; Biphenyl Compounds; Cardiotonic Agents; Creatine Kinase, MB Form; Dioscorea;

2010
A novel phytochemical, digoxigenin-3-O-rutin in the amelioration of isoproterenol-induced myocardial infarction in rat: a comparison with digoxin.
    Cardiovascular therapeutics, 2012, Volume: 30, Issue:3

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Cardiotonic Ag

2012
Pyruvate attenuates cardiac dysfunction and oxidative stress in isoproterenol-induced cardiotoxicity.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Disease Models, Animal; Heart; Hemodynamics;

2012
Preventive effects of vanillic acid on lipids, bax, bcl-2 and myocardial infarct size on isoproterenol-induced myocardial infarcted rats: a biochemical and in vitro study.
    Cardiovascular toxicology, 2011, Volume: 11, Issue:1

    Topics: Animals; bcl-2-Associated X Protein; Biphenyl Compounds; Creatine Kinase, MB Form; Disease Models, A

2011
Cardiomyocytes from phorbol myristate acetate-activated mesenchymal stem cells restore electromechanical function in infarcted rat hearts.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Jan-04, Volume: 108, Issue:1

    Topics: Analysis of Variance; Animals; Blotting, Western; Cell- and Tissue-Based Therapy; Connexin 43; Cytok

2011
Comments on Vennila and Pugalendi. Vennila L, Pugalendi KV. Protective effect of sesamol against myocardial infarction caused by isoproterenol in Wistar rats. Redox Rep 2010; 15: 36-42.
    Redox report : communications in free radical research, 2010, Volume: 15, Issue:6

    Topics: Alanine Transaminase; Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Benzodioxol

2010
Time-dependent responses of rat troponin I and cardiac injury following isoproterenol administration.
    Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, 2011, Volume: 8, Issue:1

    Topics: Animals; Biomarkers; Cardiotonic Agents; Disease Models, Animal; Heart; Isoproterenol; Male; Myocard

2011
Impact of selenium on the leukotriene B4 synthesis pathway during isoproterenol-induced myocardial infarction in experimental rats.
    Inflammation, 2012, Volume: 35, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium-Transporting ATPases; Epoxide Hyd

2012
An oral formulation of angiotensin-(1-7) produces cardioprotective effects in infarcted and isoproterenol-treated rats.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:3

    Topics: Administration, Oral; Analysis of Variance; Angiotensin I; Animals; Blood Pressure; Cardiomegaly; Ca

2011
Ellagic acid ameliorates isoproterenol induced oxidative stress: Evidence from electrocardiological, biochemical and histological study.
    European journal of pharmacology, 2011, May-20, Volume: 659, Issue:1

    Topics: Animals; Blood Pressure; Cardiotonic Agents; Electrocardiography; Ellagic Acid; Isoproterenol; Male;

2011
Effect of Inula racemosa root extract on cardiac function and oxidative stress against isoproterenol-induced myocardial infarction.
    Indian journal of biochemistry & biophysics, 2011, Volume: 48, Issue:1

    Topics: Animals; Catalase; Creatine Kinase, MB Form; Glutathione; Glutathione Peroxidase; Heart Rate; Hemody

2011
Sesamol attenuates isoproterenol-induced acute myocardial infarction via inhibition of matrix metalloproteinase-2 and -9 expression in rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 27, Issue:3-4

    Topics: Acute Disease; Animals; Antioxidants; Benzodioxoles; Blood Pressure; Creatine Kinase, MB Form; Elect

2011
Effect of 20(S)-protopanaxatriol and its epimeric derivatives on myocardial injury induced by isoproterenol.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Cardiomyopathies; Creatine Kinase; Glutathione Pero

2011
An in vivo and in vitro study on the protective effects of N-acetylcysteine on mitochondrial dysfunction in isoproterenol treated myocardial infarcted rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:1-2

    Topics: Acetylcysteine; Animals; Antioxidants; Creatine Kinase; Data Interpretation, Statistical; Disease Mo

2013
Pretreatment with morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol-induced myocardial infarction in rats.
    Journal of natural medicines, 2012, Volume: 66, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Biomarkers; Disease Models, Animal; Flavonoids; Glycoproteins; I

2012
Pharmacodynamics of ellagic acid on cardiac troponin-T, lyosomal enzymes and membrane bound ATPases: mechanistic clues from biochemical, cytokine and in vitro studies.
    Chemico-biological interactions, 2011, Sep-05, Volume: 193, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Biphenyl Compounds; Creatine Kinase; Cytokines; Ellagic Acid; En

2011
Ganoderma lucidum ameliorate mitochondrial damage in isoproterenol-induced myocardial infarction in rats by enhancing the activities of TCA cycle enzymes and respiratory chain complexes.
    International journal of cardiology, 2013, Apr-30, Volume: 165, Issue:1

    Topics: Animals; Antioxidants; Citric Acid Cycle; Creatine Kinase; Drugs, Chinese Herbal; Electron Transport

2013
A biochemical, electrocardiographic, electrophoretic, histopathological and in vitro study on the protective effects of (-)epicatechin in isoproterenol-induced myocardial infarcted rats.
    European journal of pharmacology, 2011, Dec-05, Volume: 671, Issue:1-3

    Topics: Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Cardiotonic Agents; Catechin; Dose-Response R

2011
Cardioprotective effect of water and ethanol extract of Salvia miltiorrhiza in an experimental model of myocardial infarction.
    Journal of ethnopharmacology, 2012, Jan-31, Volume: 139, Issue:2

    Topics: Administration, Oral; Animals; Biomarkers; Camphanes; Cardiotonic Agents; Disease Models, Animal; Dr

2012
Preventive effects of N-acetyl cysteine on lipids, lipoproteins and myocardial infarct size in isoproterenol induced myocardial infarcted rats: an in vivo and in vitro study.
    European journal of pharmacology, 2012, Feb-29, Volume: 677, Issue:1-3

    Topics: Acetylcysteine; Animals; Biomarkers; Free Radical Scavengers; Isoproterenol; Lipoproteins; Liver; Ma

2012
Shortened Ca2+ signaling refractoriness underlies cellular arrhythmogenesis in a postinfarction model of sudden cardiac death.
    Circulation research, 2012, Feb-17, Volume: 110, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Caffeine; Calcium Channel Agonists; Calcium Signali

2012
The autoimmune nature of post-infarct myocardial healing: oral tolerance to cardiac antigens as a novel strategy to improve cardiac healing.
    Autoimmunity, 2012, Volume: 45, Issue:3

    Topics: Animals; Autoantigens; Autoimmunity; Cytokines; Disease Models, Animal; Female; Forkhead Transcripti

2012
Insulin like growth factor-1 (IGF-1) causes overproduction of IL-8, an angiogenic cytokine and stimulates neovascularization in isoproterenol-induced myocardial infarction in rats.
    International journal of molecular sciences, 2011, Volume: 12, Issue:12

    Topics: Animals; Insulin-Like Growth Factor I; Interleukin-8; Isoproterenol; Male; Myocardial Infarction; My

2011
Overexpression of apolipoprotein B attenuates pathologic cardiac remodeling and hypertrophy in response to catecholamines and after myocardial infarction in mice.
    Scandinavian journal of clinical and laboratory investigation, 2012, Volume: 72, Issue:3

    Topics: Animals; Apolipoproteins B; Cardiomegaly; Echocardiography; Heart; Humans; Isoproterenol; Male; Mice

2012
Effect of ursolic acid treatment on apoptosis and DNA damage in isoproterenol-induced myocardial infarction.
    Biochimie, 2012, Volume: 94, Issue:5

    Topics: Animals; Apoptosis; Blotting, Western; DNA Damage; DNA Fragmentation; Electrophoresis, Polyacrylamid

2012
Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on "system to system" mode.
    Journal of translational medicine, 2012, Feb-08, Volume: 10

    Topics: Animals; Cell Membrane Permeability; Cell Movement; Cell Proliferation; Creatine Kinase; Discriminan

2012
Comparing effects of lacidipine, ramipril, and valsartan against experimentally induced myocardial infarcted rats.
    Cardiovascular toxicology, 2012, Volume: 12, Issue:2

    Topics: Administration, Oral; Animals; Cardiotonic Agents; Dihydropyridines; Dose-Response Relationship, Dru

2012
Protective effect of morin on cardiac mitochondrial function during isoproterenol-induced myocardial infarction in male Wistar rats.
    Redox report : communications in free radical research, 2012, Volume: 17, Issue:1

    Topics: Animals; Antioxidants; Cell Membrane; Electron Transport Complex IV; Enzyme Activation; Flavonoids;

2012
Sympathetic stimulation increases dispersion of repolarization in humans with myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2012, May-01, Volume: 302, Issue:9

    Topics: Action Potentials; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Cardiomyopathies; Catheter Abl

2012
Anti-inflammatory and anti-apoptotic effects of Crataegus oxyacantha on isoproterenol-induced myocardial damage.
    Molecular and cellular biochemistry, 2012, Volume: 367, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Catalase; Crataegus; Creatine Kinase; Cyclooxygenase 2

2012
Cardioprotective effect of HPLC standardized ethanolic extract of Terminalia pallida fruits against isoproterenol-induced myocardial infarction in albino rats.
    Journal of ethnopharmacology, 2012, May-07, Volume: 141, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Antioxidants; Biomarkers; Cardiovascular Agents; Chromatography,

2012
[Effect of compatibilities and proportions of shuanglong formula on acute myocardial infarction in rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2011, Volume: 36, Issue:22

    Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Electrocardiography; Isoproterenol; Male; My

2011
Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats.
    Atherosclerosis, 2012, Volume: 222, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Apoptosis; Berberine; Cardioto

2012
Morin protects heart from beta-adrenergic-stimulated myocardial infarction: an electrocardiographic, biochemical, and histological study in rats.
    Journal of physiology and biochemistry, 2012, Volume: 68, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Biomarkers; Electrocardiography; Flavonoids; Isopro

2012
Dexrazoxane provided moderate protection in a catecholamine model of severe cardiotoxicity.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:4

    Topics: Animals; Calcium; Cardiotonic Agents; Disease Models, Animal; Hemodynamics; Iron; Iron Chelating Age

2012
Amaranthus viridis Linn., a common spinach, modulates C-reactive protein, protein profile, ceruloplasmin and glycoprotein in experimental induced myocardial infarcted rats.
    Journal of the science of food and agriculture, 2012, Volume: 92, Issue:12

    Topics: Amaranthus; Animals; Blood Proteins; C-Reactive Protein; Ceruloplasmin; Glycoproteins; Isoproterenol

2012
The cardiac expression of Mas receptor is responsive to different physiological and pathological stimuli.
    Peptides, 2012, Volume: 35, Issue:2

    Topics: Angiotensin I; Animals; Cardiomegaly; Desoxycorticosterone; Hypertension; Isoproterenol; Male; Motor

2012
Increased expression of calcium-sensing receptors in atherosclerosis confers hypersensitivity to acute myocardial infarction in rats.
    Molecular and cellular biochemistry, 2012, Volume: 366, Issue:1-2

    Topics: Animals; Aorta, Abdominal; Apoptosis; Apoptosis Regulatory Proteins; Atherosclerosis; Cholesterol; C

2012
The plating of rat scar myofibroblasts on matrigel unmasks a novel phenotype; the self assembly of lumen-like structures.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:7

    Topics: Actins; Animals; Carbocyanines; Cell Culture Techniques; Cell Differentiation; Cell Separation; Cell

2012
Protective effects of N-acetyl cysteine on membrane-bound adenosine triphosphatases and minerals in isoproterenol-induced myocardial-infarcted rats: an in vivo and in vitro study.
    Journal of biochemical and molecular toxicology, 2012, Volume: 26, Issue:7

    Topics: Acetylcysteine; Adenosine Triphosphatases; Animals; Cardiotonic Agents; Cell Membrane; Enzyme Activa

2012
Protective efficacy of ellagic acid on glycoproteins, hematological parameters, biochemical changes, and electrolytes in myocardial infarcted rats.
    Journal of biochemical and molecular toxicology, 2012, Volume: 26, Issue:7

    Topics: Animals; Blood Glucose; Blood Proteins; Cardiotonic Agents; Electrolytes; Ellagic Acid; Glycoprotein

2012
Rosuvastatin promotes angiogenesis and reverses isoproterenol-induced acute myocardial infarction in rats: role of iNOS and VEGF.
    European journal of pharmacology, 2012, Sep-15, Volume: 691, Issue:1-3

    Topics: Acute Disease; Animals; Body Weight; Electrocardiography; Fluorobenzenes; Heart Ventricles; Isoprote

2012
Blockers of sulfonylureas receptor 1 subunits may lead to cardiac protection against isoprenaline-induced injury in obese rats.
    European journal of pharmacology, 2012, Sep-05, Volume: 690, Issue:1-3

    Topics: Animals; ATP-Binding Cassette Transporters; Cell Size; Gene Expression Regulation; Gliclazide; Heart

2012
The mechanism of beta-adrenergic preconditioning: roles for adenosine and ROS during triggering and mediation.
    Basic research in cardiology, 2012, Volume: 107, Issue:5

    Topics: Adenosine; Animals; Ethanolamines; Extracellular Signal-Regulated MAP Kinases; Formoterol Fumarate;

2012
Turbinaria conoides (J. Agardh) sulfated polysaccharide protects rat's heart against myocardial injury.
    International journal of biological macromolecules, 2012, Jun-01, Volume: 50, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Calcium; Cell Membrane; Creatine Kinase; Disease Models, Animal;

2012
Maslinic acid protects against isoproterenol-induced cardiotoxicity in albino Wistar rats.
    Journal of medicinal food, 2012, Volume: 15, Issue:8

    Topics: Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Humans; Isoproterenol; Male; Myocardial In

2012
Protective effects of thymol on altered plasma lipid peroxidation and nonenzymic antioxidants in isoproterenol-induced myocardial infarcted rats.
    Journal of biochemical and molecular toxicology, 2012, Volume: 26, Issue:9

    Topics: Animals; Antioxidants; Cardiotonic Agents; Creatine Kinase, MB Form; Dose-Response Relationship, Dru

2012
Effect of ursolic acid on cardiac marker enzymes, lipid profile and macroscopic enzyme mapping assay in isoproterenol-induced myocardial ischemic rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:11

    Topics: Animals; Biomarkers; Cardiotonic Agents; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Creatine

2012
Protective effects of sinapic acid on lysosomal dysfunction in isoproterenol induced myocardial infarcted rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:11

    Topics: Animals; beta-Galactosidase; Cardiotonic Agents; Cathepsin B; Cathepsin D; Coumaric Acids; Creatine

2012
Efficacy of sesamol on plasma and tissue lipids in isoproterenol-induced cardiotoxicity in Wistar rats.
    Archives of pharmacal research, 2012, Volume: 35, Issue:8

    Topics: Animals; Antioxidants; Benzodioxoles; Disease Models, Animal; Dose-Response Relationship, Drug; Hypo

2012
Preconditioning with diosgenin and treadmill exercise preserves the cardiac toxicity of isoproterenol in rats.
    Journal of physiology and biochemistry, 2013, Volume: 69, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Diosgenin; Disease Models, Animal; Free Radicals; G

2013
Preventive effects of Egyptian sweet marjoram (Origanum majorana L.) leaves on haematological changes and cardiotoxicity in isoproterenol-treated albino rats.
    Cardiovascular toxicology, 2013, Volume: 13, Issue:2

    Topics: Animals; Blood Coagulation; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship,

2013
The effect of c-fos on acute myocardial infarction and the significance of metoprolol intervention in a rat model.
    Cell biochemistry and biophysics, 2013, Volume: 65, Issue:2

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Female; Gene Expression;

2013
Cardioprotective effect of lycopene against isoproterenol-induced myocardial infarction in rats.
    Human & experimental toxicology, 2013, Volume: 32, Issue:5

    Topics: Animals; Carotenoids; Creatine Kinase, MB Form; Glutathione; Heart; Hemodynamics; Isoproterenol; Lip

2013
Short-term treatment with metformin suppresses toll like receptors (TLRs) activity in isoproterenol-induced myocardial infarction in rat: are AMPK and TLRs connected?
    International immunopharmacology, 2012, Volume: 14, Issue:4

    Topics: Adrenergic beta-Agonists; AMP-Activated Protein Kinases; Animals; Gene Expression Regulation; Hypogl

2012
Cardioprotective effect of paeonol and danshensu combination on isoproterenol-induced myocardial injury in rats.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Acetophenones; Animals; Antioxidants; bcl-2-Associated X Protein; Biomarkers; Body Weight; Cardioton

2012
Preventive effects of p-coumaric acid on lysosomal dysfunction and myocardial infarct size in experimentally induced myocardial infarction.
    European journal of pharmacology, 2013, Jan-15, Volume: 699, Issue:1-3

    Topics: Animals; Antioxidants; Coumaric Acids; Disease Models, Animal; Free Radical Scavengers; Isoprotereno

2013
Protective effects of sinapic acid on cardiac hypertrophy, dyslipidaemia and altered electrocardiogram in isoproterenol-induced myocardial infarcted rats.
    European journal of pharmacology, 2013, Jan-15, Volume: 699, Issue:1-3

    Topics: Animals; Antioxidants; Cardiomegaly; Coumaric Acids; Dyslipidemias; Electrocardiography; Hydroxymeth

2013
The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle.
    Journal of molecular and cellular cardiology, 2013, Volume: 56

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Carbachol; Cardiotonic Agents; GTP-Binding Pro

2013
Preventive effects of (-) epicatechin on altered adenosine triphosphatases and minerals in isoproterenol-induced myocardial infarcted rats.
    Journal of biochemical and molecular toxicology, 2012, Volume: 26, Issue:12

    Topics: Adenosine Triphosphatases; Animals; Catechin; Isoproterenol; Lipid Peroxidation; Male; Minerals; Myo

2012
(-) Epicatechin attenuates mitochondrial damage by enhancing mitochondrial multi-marker enzymes, adenosine triphosphate and lowering calcium in isoproterenol induced myocardial infarcted rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 53

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Biomarkers; Calcium; Catechin; Citric Acid Cycle; Cre

2013
Protective effect of neferine against isoproterenol-induced cardiac toxicity.
    Cardiovascular toxicology, 2013, Volume: 13, Issue:2

    Topics: Animals; Benzylisoquinolines; Biomarkers; Cardiotonic Agents; Drugs, Chinese Herbal; Enzymes; Heart;

2013
Folic acid and vitamin B(12) supplementation attenuates isoprenaline-induced myocardial infarction in experimental hyperhomocysteinemic rats.
    Pharmacological research, 2002, Volume: 46, Issue:3

    Topics: Animals; Blood Pressure; Creatine Kinase; Folic Acid; Glutathione; Heart Rate; Hemodynamics; Hyperho

2002
Overexpression of Na+/Ca2+ exchanger gene attenuates postinfarction myocardial dysfunction.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Disease Models, Animal; Disease Progression; Electrocard

2002
Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol.
    The Journal of biological chemistry, 2003, Jan-03, Volume: 278, Issue:1

    Topics: Animals; Calcium; Calcium-Binding Proteins; Cyclic AMP-Dependent Protein Kinases; Disease Models, An

2003
Toxic cardiac effects of catecholamines: role of beta-adrenoceptor downregulation.
    European journal of pharmacology, 2002, Dec-05, Volume: 456, Issue:1-3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Blood Pressure

2002
Overexpression of Na+/Ca2+ exchanger attenuates postinfarcted myocardial dysfunction.
    Annals of the New York Academy of Sciences, 2002, Volume: 976

    Topics: Adrenergic beta-Agonists; Animals; Disease Models, Animal; Gene Expression Regulation; Hemodynamics;

2002
Effect of fish oil on mitochondrial respiration in isoproterenol induced myocardial infarction in rats.
    Indian journal of experimental biology, 2002, Volume: 40, Issue:3

    Topics: Animals; Fish Oils; Isoproterenol; Lipid Peroxidation; Male; Mitochondria, Heart; Myocardial Infarct

2002
Effect of isoproterenol on lipid peroxidation and antioxidant enzymes of myocardial tissue of mice and protection by quinidine.
    Molecular and cellular biochemistry, 2003, Volume: 245, Issue:1-2

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Aspartate Aminotransferases; Body Weight; Cardiotonic

2003
Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2003, Volume: 36, Issue:5

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Colforsin; Disease M

2003
Combined sodium and calcium channel blockade in prevention of lethal arrhythmias.
    Journal of cardiovascular pharmacology, 2003, Volume: 41, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Death, Sudde

2003
[Variation of endogeneous ET, CGRP and NO in myocardial ischemia in rats and the regulatory effect of xinshuping].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2002, Volume: 27, Issue:7

    Topics: Animals; Calcitonin Gene-Related Peptide; Cardiotonic Agents; Drug Combinations; Drugs, Chinese Herb

2002
Effect of D-003 on isoproterenol-induced myocardial necrosis in rats.
    Journal of medicinal food, 2003,Spring, Volume: 6, Issue:1

    Topics: Animals; Aspirin; Disease Models, Animal; Fatty Acids; Isoproterenol; Male; Myocardial Infarction; M

2003
Inotropic responses to isoproterenol in congestive heart failure subsequent to myocardial infarction in rats.
    Journal of cardiac failure, 1995, Volume: 1, Issue:5

    Topics: Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Colforsin; Coronary Vessels; Heart Failu

1995
Effect of L-arginine and L-lysine on lysosomal hydrolases and membrane bound phosphatases in experimentally induced myocardial infarction in rats.
    Molecular and cellular biochemistry, 2003, Volume: 247, Issue:1-2

    Topics: Animals; Arginine; Cell Membrane; Disease Models, Animal; Hydrolases; Isoproterenol; Lysine; Lysosom

2003
Protective effects of melatonin against myocardial injury induced by isoproterenol in rats.
    Journal of pineal research, 2003, Volume: 35, Issue:2

    Topics: Animals; Cardiotonic Agents; Heart; Isoproterenol; Male; Melatonin; Myocardial Infarction; Myocardiu

2003
Asystole complicating acute myocardial infarction; survival with the aid of a cardiac pacemaker and intravenous administration of isoproterenol.
    Journal of the American Medical Association, 1958, Dec-20, Volume: 168, Issue:16

    Topics: Administration, Intravenous; Arrhythmias, Cardiac; Heart Arrest; Humans; Isoproterenol; Myocardial I

1958
An infarct-like myocardial lesion and other toxic manifestations produced by isoproterenol in the rat.
    A.M.A. archives of pathology, 1959, Volume: 67, Issue:4

    Topics: Animals; Isoproterenol; Myocardial Infarction; Rats; Sympathomimetics

1959
The effect of breed, age, and sex on myocardial necrosis produced by isoproterenol in the rat.
    Journal of gerontology, 1959, Volume: 14, Issue:2

    Topics: Aging; Animals; Cardiomyopathies; Disease; Heart Diseases; Isoproterenol; Myocardial Infarction; Myo

1959
Stokes-Adams attacks complicating acute myocardial infarction; their treatment with continuous intravenous infusion of isopropylnorepinephrine.
    The New England journal of medicine, 1959, Jun-11, Volume: 260, Issue:24

    Topics: Adams-Stokes Syndrome; Heart; Heart Block; Humans; Infusions, Intravenous; Isoproterenol; Myocardial

1959
Use of isoproterenol in the treatment of complete heart block complicating acute myocardial infarction.
    The American journal of cardiology, 1961, Volume: 7

    Topics: Atrioventricular Block; Heart; Heart Block; Humans; Isoproterenol; Myocardial Infarction; Sympathomi

1961
Severe myocardial necrosis produced by isoproterenol in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1959, Oct-01, Volume: 122

    Topics: Animals; Isoproterenol; Myocardial Infarction; Myocardium; Rats; Sympathomimetics

1959
[Action of a monoamine oxidase inhibitor (Niamid) on various experimental vascular lesions in the rabbit (allergic arteritis, myocardial necrosis caused by isoproterenol, aortic medionecrosis, venous and arterial thrombosis)].
    Chemotherapia, 1962, Volume: 4

    Topics: Animals; Aorta; Arteritis; Isoproterenol; Monoamine Oxidase Inhibitors; Myocardial Infarction; Myoca

1962
Isoproterenol-induced myocardial infarction in animals.
    Archives of pathology, 1962, Volume: 73

    Topics: Animals; Cardiovascular Diseases; Isoproterenol; Myocardial Infarction; Sympathomimetics

1962
The pathogenesis of atrial infarction. Experimental data.
    The American journal of pathology, 1962, Volume: 41

    Topics: Infarction; Isoproterenol; Myocardial Infarction

1962
[Influence of amine oxidase inhibitors, vasodilator and tranquilizing agents on experimental isoproterenol-induced myocardial necrosis].
    Arzneimittel-Forschung, 1962, Volume: 12

    Topics: Humans; Isoproterenol; Monoamine Oxidase Inhibitors; Myocardial Infarction; Oxidoreductases; Sympath

1962
[Experimental infarct-like changes of the myocardium under the influence of isadrine (isopropylnoradrenaline)].
    Arkhiv patologii, 1963, Volume: 25

    Topics: Isoproterenol; Myocardial Infarction; Myocardium

1963
[Experimental induction of necroses in the myocardium with isadrine (isopropylnoradrenalin)].
    Kardiologiia, 1963, Volume: 3

    Topics: Isoproterenol; Myocardial Infarction; Myocardium; Necrosis

1963
THE SIGNIFICANCE OF SINUS BRADYCARDIA IN ACUTE MYOCARDIAL INFARCTION.
    Diseases of the chest, 1963, Volume: 44

    Topics: Anterior Wall Myocardial Infarction; Arrhythmia, Sinus; Bradycardia; Electrocardiography; Humans; Is

1963
THE SIGNIFICANCE OF FACTORS MODIFYING THE DEVELOPMENT OF ISOPROTERENOL-INDUCED MYOCARDIAL NECROSIS.
    American heart journal, 1963, Volume: 66

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Diet; Dietary Carbohydrates; Dietary Fats; Estrogens; Estron

1963
ISOPROTERENOL-INDUCED HEART NECROSIS, AN EXPERIMENTAL MODEL FOR THE STUDY OF ANGINA PECTORIS AND MYOCARDIAL INFARCT.
    Revue canadienne de biologie, 1963, Volume: 22

    Topics: Angina Pectoris; Aspartate Aminotransferases; Heart; Isocarboxazid; Isoproterenol; L-Lactate Dehydro

1963
SURGICAL TREATMENT OF COMPLETE HEART BLOCK. AN ANALYSIS OF 36 CASES.
    JAMA, 1964, Jul-13, Volume: 189

    Topics: Atropine; Chlorothiazide; Diabetes Mellitus; Ephedrine; Geriatrics; Heart Block; Heart Failure; Huma

1964
ISOPROTERENOL-INDUCED MYOCARDIAL NECROSIS. A HISTOCHEMICAL AND ELECTRON MICROSCOPIC STUDY.
    American heart journal, 1964, Volume: 68

    Topics: Coronary Disease; Electron Transport Complex IV; Electrons; Fluorescence; Glycogen; Heart Diseases;

1964
DIRECT WIRE ELECTRICAL STIMULATION FOR ACUTE POSTSURGICAL AND POSTINFARCTION COMPLETE HEART BLOCK.
    Annals of the New York Academy of Sciences, 1964, Jun-11, Volume: 111

    Topics: Drug Therapy; Electric Stimulation; Electrocardiography; Heart Block; Humans; Isoproterenol; Myocard

1964
[TREATMENT OF VENTRICULAR TACHYCARDIA WITH ALUPENT].
    Deutsche medizinische Wochenschrift (1946), 1965, Feb-19, Volume: 90

    Topics: Drug Therapy; Electrocardiography; Isoproterenol; Metaproterenol; Myocardial Infarction; Procainamid

1965
HEMODYNAMIC DETERMINANTS OF THE AMPLITUDE OF THE FIRST HEART SOUND.
    Circulation research, 1965, Volume: 16

    Topics: Animals; Aortic Diseases; Atropine; Dogs; Electrocardiography; Epinephrine; Heart Auscultation; Hear

1965
TREATMENT OF SHOCK IN MAN BASED ON HEMODYNAMIC DIAGNOSIS.
    Surgery, gynecology & obstetrics, 1965, Volume: 120

    Topics: Blood; Blood Gas Analysis; Blood Pressure; Blood Pressure Determination; Blood Transfusion; Blood Vo

1965
STEROIDS PRODUCED IN VITRO BY ADRENAL GLANDS OF NORMAL AND ARTERIOSCLEROTIC RATS DURING AND AFTER DRUG-INDUCED MYOCARDIAL NECROSIS.
    Circulation research, 1965, Volume: 16

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Aldosterone; Arteriosclerosis; Heart Failure; In Vitro Tech

1965
THE COURSE OF HEALING OF EXPERIMENTAL MYOCARDIAL INFARCTION IN THE RAT.
    Cor et vasa, 1965, Volume: 7

    Topics: Cardiovascular Diseases; Cicatrix; Isoproterenol; Myocardial Infarction; Pathology; Pharmacology; Ra

1965
CARDIAC ABNORMALITIES ASSOCIATED WITH CAROTID-SINUS SYNDROME.
    Lancet (London, England), 1965, Jul-31, Volume: 2, Issue:7405

    Topics: Arrhythmias, Cardiac; Atropine; Carotid Sinus; Denervation; Drug Therapy; Electrocardiography; Human

1965
[ON THE PATHOGENESIS AND PHARMACOLOGICAL INFLUENCE OF MYOCARDIAL NECROSES CAUSED BY ISOPRENALINE POISONING].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Heart Diseases; Isoproterenol; Myocardial Infarction; Rats; Research; Toxicology

1964
Protection, by coronary ligature, against isoproterenol-induced myocardial necroses.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1960, Volume: 104

    Topics: Coronary Vessels; Heart; Isoproterenol; Ligation; Myocardial Infarction; Myocardium; Necrosis; Sympa

1960
Biochemical changes on the cardioprotective effect of nicorandil and amlodipine during experimental myocardial infarction in rats.
    Pharmacological research, 2003, Volume: 48, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amlodipine; Animals; Cardiovascular Agents; Drug Syne

2003
Angiotensin receptor blockade improves myocardial beta-adrenergic receptor signaling in postinfarction left ventricular remodeling: a possible link between beta-adrenergic receptor kinase-1 and protein kinase C epsilon isoform.
    Journal of the American College of Cardiology, 2004, Jan-07, Volume: 43, Issue:1

    Topics: Adrenergic beta-Agonists; Angiotensin II Type 1 Receptor Blockers; Animals; Isoproterenol; Male; Myo

2004
Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy.
    Circulation research, 2004, Apr-16, Volume: 94, Issue:7

    Topics: Adenoviridae; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Atri

2004
Chronic oral administration of raw garlic protects against isoproterenol-induced myocardial necrosis in rat.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2003, Volume: 136, Issue:4

    Topics: Animals; Antioxidants; Catalase; Dose-Response Relationship, Drug; Female; Garlic; Glutathione; Glut

2003
Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor.
    Circulation research, 2004, Apr-02, Volume: 94, Issue:6

    Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Animals; Benzylamines; Calcium-Calmodulin-Dependent P

2004
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction.
    Circulation research, 2004, May-14, Volume: 94, Issue:9

    Topics: Adrenergic beta-Agonists; Animals; Enzyme Induction; Fibrosis; Humans; Hypertrophy; Hypertrophy, Lef

2004
NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction.
    Circulation research, 2004, May-28, Volume: 94, Issue:10

    Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclosporine; DNA

2004
Wine polyphenols induce hypotension, and decrease cardiac reactivity and infarct size in rats: involvement of nitric oxide.
    British journal of pharmacology, 2004, Volume: 142, Issue:4

    Topics: Administration, Oral; Aldehydes; Animals; Blood Pressure; Blotting, Western; Carbachol; Coronary Cir

2004
Dispersion of ventricular mRNA of RyR2 and SERCA2 associated with arrhythmogenesis in rats.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Berberine; Calcium Channels, L-Type; Calcium-

2004
Effect of Calotropis procera latex on isoproterenol induced myocardial infarction in albino rats.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2004, Volume: 11, Issue:4

    Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Calotropis; Cardio

2004
Improvement of cardiac function and beta-adrenergic signal transduction by propionyl L-carnitine in congestive heart failure due to myocardial infarction.
    Coronary artery disease, 2004, Volume: 15, Issue:1

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiotonic Agent

2004
Effect of squalene on tissue defense system in isoproterenol-induced myocardial infarction in rats.
    Pharmacological research, 2004, Volume: 50, Issue:3

    Topics: Animals; Antioxidants; Free Radicals; Isoproterenol; Lipid Peroxidation; Liver; Male; Myocardial Inf

2004
Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment.
    Molecular and cellular biochemistry, 2004, Volume: 260, Issue:1-2

    Topics: Animals; Blood Pressure; Catalase; Creatine Kinase; Female; Glutathione; Glutathione Peroxidase; Hea

2004
Cardioprotective effect of tincture of Crataegus on isoproterenol-induced myocardial infarction in rats.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:7

    Topics: Animals; Crataegus; Fruit; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction; Myocardiu

2004
Comparative account of certain enzymes in the serum of homo-iothermal vertebrates subjected to production of myocardial infarction by isoproterenol hydrochloride.
    Journal of environmental biology, 2003, Volume: 24, Issue:4

    Topics: Acetylcholinesterase; Alanine Transaminase; Animals; Aspartate Aminotransferases; Columbidae; Diseas

2003
Effect of garlic (Allium sativum) on lipid peroxidation in experimental myocardial infarction in rats.
    Journal of ethnopharmacology, 2004, Volume: 94, Issue:1

    Topics: Allyl Compounds; Animals; Garlic; Glutathione Transferase; Isoproterenol; Lipid Peroxidation; Male;

2004
Protective effect of Terminalia chebula against experimental myocardial injury induced by isoproterenol.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:2

    Topics: Adrenergic beta-Agonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Fruit; Heart;

2004
Role of Arogh, a polyherbal formulation to mitigate oxidative stress in experimental myocardial infarction.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:2

    Topics: Antioxidants; Catalase; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Isoproterenol;

2004
Treatment of acute myocardial infarction by hepatocyte growth factor gene transfer: the first demonstration of myocardial transfer of a "functional" gene using ultrasonic microbubble destruction.
    Journal of the American College of Cardiology, 2004, Aug-04, Volume: 44, Issue:3

    Topics: Animals; Capillaries; Cicatrix; Disease Models, Animal; Gene Expression Regulation; Gene Transfer Te

2004
Thyroid hormone analog, DITPA, improves endothelial nitric oxide and beta-adrenergic mediated vasorelaxation after myocardial infarction.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:4

    Topics: Acetylcholine; Animals; Cattle; Cells, Cultured; Coronary Vessels; Diiodothyronines; Endothelium, Va

2004
Role of myocardial neuronal nitric oxide synthase-derived nitric oxide in beta-adrenergic hyporesponsiveness after myocardial infarction-induced heart failure in rat.
    Circulation, 2004, Oct-19, Volume: 110, Issue:16

    Topics: Adrenergic beta-Agonists; Animals; Autocrine Communication; Caveolin 3; Caveolins; Dobutamine; Enzym

2004
Isoproterenol-induced myocardial infarction in rabbits. Protection by propranolol or labetalol: a proposed non-invasive procedure.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2004, Volume: 23, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Electrocardiography; Isoproterenol; Labetalol; Lipid Peroxides

2004
Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy.
    Circulation research, 2004, Nov-12, Volume: 95, Issue:10

    Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Allopurinol; Animals; Antioxidants; Calcium Signaling;

2004
Changes in beta-adrenoceptors in heart failure due to myocardial infarction are attenuated by blockade of renin-angiotensin system.
    Molecular and cellular biochemistry, 2004, Volume: 263, Issue:1-2

    Topics: Adenylyl Cyclases; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Enalap

2004
Myocardial infarction non-invasively induced in rabbits by administering isoproterenol and vasopressin: protective effects exerted by verapamil.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:6

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Electrocardiography; Hear

2004
Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice.
    Circulation research, 2005, Jan-07, Volume: 96, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Cardiomegaly; Coronary Disease; Cyclin D1; Cyclin D2; Cyclin

2005
Impact of beta-myosin heavy chain expression on cardiac function during stress.
    Journal of the American College of Cardiology, 2004, Dec-21, Volume: 44, Issue:12

    Topics: Animals; Body Weight; Cardiac Output, Low; Cardiomegaly; Cardiotonic Agents; Chronic Disease; Dobuta

2004
Inhibition of catecholamine-induced cardiac fibrosis by an aldosterone antagonist.
    Journal of cardiovascular pharmacology, 2005, Volume: 45, Issue:1

    Topics: Adrenergic beta-Agonists; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Anim

2005
Comparative effects of Aegle marmelos extract and alpha-tocopherol on serum lipids, lipid peroxides and cardiac enzyme levels in rats with isoproterenol-induced myocardial infarction.
    Singapore medical journal, 2005, Volume: 46, Issue:2

    Topics: Adrenergic beta-Agonists; Aegle; alpha-Tocopherol; Animals; Antioxidants; Biomarkers; Female; Isopro

2005
Protective effects of dantrolene against myocardial injury induced by isoproterenol in rats: biochemical and histological findings.
    International journal of cardiology, 2005, Feb-28, Volume: 98, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Dantrolene; Disease Models, Animal; Heart; Isoproterenol; Male; M

2005
The role of beta-adrenergic receptor signaling in cardioprotection.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:8

    Topics: Animals; Cardiotonic Agents; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Protein alpha Subunit

2005
Diverse phenotypes of outward currents in cells that have survived in the 5-day-infarcted heart.
    American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Cell Survival; Dogs; Electric Conductivity; In Vitro Techniques;

2005
Defective excitation-contraction coupling in hearts of rats with congestive heart failure.
    Acta physiologica Scandinavica, 2005, Volume: 184, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Echocardiography; Heart Failure; Isoproterenol; Male; My

2005
2APB- and JTV519(K201)-sensitive micro Ca2+ waves in arrhythmogenic Purkinje cells that survive in infarcted canine heart.
    Heart rhythm, 2004, Volume: 1, Issue:2

    Topics: Adrenergic beta-Agonists; Aniline Compounds; Animals; Boron Compounds; Calcium; Calcium Channel Bloc

2004
Carvedilol blockade of alpha1- and beta-adrenoceptor induced inotropic responses in rats with congestive heart failure.
    European journal of pharmacology, 2005, May-23, Volume: 516, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbaz

2005
Antioxidant activity of DHC-1, an herbal formulation, in experimentally-induced cardiac and renal damage.
    Phytotherapy research : PTR, 2005, Volume: 19, Issue:3

    Topics: Animals; Antioxidants; Bacopa; Cisplatin; Female; Glycyrrhiza; Isoproterenol; Kidney Diseases; Male;

2005
Animal models of cardiac fibrosis.
    Methods in molecular medicine, 2005, Volume: 117

    Topics: Aldosterone; Angiotensin II; Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Heart Diseases;

2005
Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury.
    The Journal of surgical research, 2006, Volume: 131, Issue:1

    Topics: Adrenergic beta-Agonists; Aging; Animals; Isoproterenol; Male; Myocardial Infarction; Myocardial Isc

2006
Liver architecture maintenance by tincture of Crataegus against isoproterenol-induced myocardially infarcted rats.
    Journal of medicinal food, 2005,Fall, Volume: 8, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Crataegus; Fruit;

2005
Protective effect of taurine on myocardial antioxidant status in isoprenaline-induced myocardial infarction in rats.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:10

    Topics: Animals; Antioxidants; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Heart; Injectio

2005
Preventive effect of Aegle marmelos leaf extract on isoprenaline-induced myocardial infarction in rats: biochemical evidence.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:10

    Topics: Administration, Oral; Aegle; Animals; Antioxidants; Aorta; Calcium-Transporting ATPases; Cell Membra

2005
Scar myofibroblasts of the infarcted rat heart express natriuretic peptides.
    Journal of cellular physiology, 2006, Volume: 207, Issue:1

    Topics: Adrenomedullin; Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Culture

2006
Synergistic interactions of ferulic acid with ascorbic acid: its cardioprotective role during isoproterenol induced myocardial infarction in rats.
    Molecular and cellular biochemistry, 2006, Volume: 283, Issue:1-2

    Topics: Animals; Antioxidants; Ascorbic Acid; Coumaric Acids; Drug Interactions; Drug Synergism; Free Radica

2006
Cardioprotective effect of mangiferin on isoproterenol induced myocardial infarction in rats.
    Indian journal of experimental biology, 2006, Volume: 44, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardiotonic Agents; Dose-Response Relati

2006
Inhibition of myocardial apoptosis by ischaemic and beta-adrenergic preconditioning is dependent on p38 MAPK.
    Cardiovascular drugs and therapy, 2006, Volume: 20, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Anisomycin; Apoptosis; Enzyme Activators; Imidazoles; In Vitro Te

2006
[Significance of isuprel infusion in unexplained syncope after myocardial infarction].
    Archives des maladies du coeur et des vaisseaux, 2006, Volume: 99, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Cardiotonic Agents; Electrophysiologic Techniq

2006
Effect of atorvastatin treatment on isoproterenol-induced myocardial infarction in rats.
    Pharmacology, 2006, Volume: 77, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Atorvastatin; Body Weight; Catalase; Glutathione; Heart; Heptano

2006
Chronic beta-adrenergic receptor stimulation induces cardiac apoptosis and aggravates myocardial ischemia/reperfusion injury by provoking inducible nitric-oxide synthase-mediated nitrative stress.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Blotting, Western; C-Reactive Protein; Heart; Immunohi

2006
Role of mangiferin on biochemical alterations and antioxidant status in isoproterenol-induced myocardial infarction in rats.
    Journal of ethnopharmacology, 2006, Aug-11, Volume: 107, Issue:1

    Topics: Animals; Antioxidants; Creatine Kinase, MB Form; Electrophoresis, Agar Gel; Isoproterenol; L-Lactate

2006
Attenuation of abnormalities in the lipid metabolism during experimental myocardial infarction induced by isoproterenol in rats: beneficial effect of ferulic acid and ascorbic acid.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Ascorbic Acid; Cardiotonic Agents; Coumaric Acids;

2006
Cardioprotective activity of A.V. Circulo in isoproterenol-induced myocardial necrosis.
    Journal of herbal pharmacotherapy, 2005, Volume: 5, Issue:4

    Topics: Administration, Oral; Animals; Cardiotonic Agents; Female; Isoproterenol; Male; Myocardial Infarctio

2005
Modulatory effect of fish oil on the myocardial antioxidant defense system in isoproterenol-induced myocardial infarction.
    Journal of basic and clinical physiology and pharmacology, 2006, Volume: 17, Issue:1

    Topics: Animals; Antioxidants; Body Weight; Catalase; Ceruloplasmin; Creatine Kinase; DNA; Fish Oils; Glutat

2006
Preventive effect of rutin, a bioflavonoid, on lipid peroxides and antioxidants in isoproterenol-induced myocardial infarction in rats.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:5

    Topics: Animals; Antioxidants; Ascorbic Acid; Aspartate Aminotransferases; Catalase; Creatine Kinase, MB For

2006
Effect of mangiferin on mitochondrial energy production in experimentally induced myocardial infarcted rats.
    Vascular pharmacology, 2006, Volume: 44, Issue:6

    Topics: Animals; Antioxidants; Blood Glucose; Disease Models, Animal; Energy Metabolism; Glutathione; Isopro

2006
PARP inhibition prevents postinfarction myocardial remodeling and heart failure via the protein kinase C/glycogen synthase kinase-3beta pathway.
    Journal of molecular and cellular cardiology, 2006, Volume: 41, Issue:1

    Topics: Animals; Cardiomegaly; Collagen Type III; Electrocardiography; Enzyme Inhibitors; Glycogen Synthase

2006
Pretreatment with alcoholic extract of Crataegus oxycantha (AEC) activates mitochondrial protection during isoproterenol - induced myocardial infarction in rats.
    Molecular and cellular biochemistry, 2006, Volume: 292, Issue:1-2

    Topics: Animals; Antioxidants; Citric Acid Cycle; Crataegus; Isoproterenol; Lipid Peroxidation; Male; Mitoch

2006
Correlation between oxidative stress and alteration of intracellular calcium handling in isoproterenol-induced myocardial infarction.
    Molecular and cellular biochemistry, 2006, Volume: 289, Issue:1-2

    Topics: Animals; Antioxidants; Calcium Signaling; Glutathione; Isoproterenol; Lipid Peroxidation; Male; Mito

2006
Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Calcium; Calcium Channel Blockers; Calcium-Binding Pro

2006
Antilipoperoxidative and antioxidant effects of S-allyl cysteine sulfoxide on isoproterenol-induced myocardial infarction in Wistar rats.
    Journal of biochemical and molecular toxicology, 2006, Volume: 20, Issue:4

    Topics: Animals; Antioxidants; Creatine Kinase; Cysteine; Isoproterenol; Lipid Peroxidation; Male; Myocardia

2006
Preventive effect of naringin on lipids, lipoproteins and lipid metabolic enzymes in isoproterenol-induced myocardial infarction in Wistar rats.
    Journal of biochemical and molecular toxicology, 2006, Volume: 20, Issue:4

    Topics: Animals; Flavanones; Hydroxymethylglutaryl CoA Reductases; Isoproterenol; Lipid Metabolism; Lipoprot

2006
Intermedin1-53 protects the heart against isoproterenol-induced ischemic injury in rats.
    European journal of pharmacology, 2006, Nov-07, Volume: 549, Issue:1-3

    Topics: Adrenomedullin; Animals; Calcitonin Receptor-Like Protein; Cyclic AMP; Dose-Response Relationship, D

2006
Differential changes in beta-adrenoceptor signal transduction in left and right ventricles of infarcted rats.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:7

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Heart Ventricles; Intracellular Fluid

2006
Synergistic salubrious effect of ferulic acid and ascorbic acid on membrane-bound phosphatases and lysosomal hydrolases during experimental myocardial infarction in rats.
    Life sciences, 2006, Dec-23, Volume: 80, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Cardiotonic Agents; C

2006
Efficacy of mangiferin on serum and heart tissue lipids in rats subjected to isoproterenol induced cardiotoxicity.
    Toxicology, 2006, Dec-07, Volume: 228, Issue:2-3

    Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Cholesterol; Fatty Acids, Nonesterified; Hear

2006
Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: biochemical and histopathological evidences.
    Toxicology, 2006, Dec-07, Volume: 228, Issue:2-3

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Ascorbic Acid; Ceruloplasmin; Enzymes; Flavanones;

2006
Antioxidant activity of Pepticare, a herbomineral formulation, in experimentally induced renal and cardiac damage.
    Journal of herbal pharmacotherapy, 2006, Volume: 6, Issue:1

    Topics: Animals; Antioxidants; Catalase; Cisplatin; Creatine Kinase, MB Form; Dose-Response Relationship, Dr

2006
Anti-ischemic effects of nimesulide, a cyclooxygenase-2 inhibitor on the ischemic model of rabbit induced by isoproterenol.
    Archives of pharmacal research, 2006, Volume: 29, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Coronary Circulation; Creatine Kinase; Cyclooxygenase 2 Inhibitor

2006
S-allylcysteine ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing cardiac mitochondrial and lysosomal enzymes.
    Life sciences, 2007, Feb-13, Volume: 80, Issue:10

    Topics: Adrenergic beta-Agonists; alpha-Tocopherol; Animals; Antineoplastic Agents; Cysteine; Electrocardiog

2007
Preventive effect of naringin on cardiac markers, electrocardiographic patterns and lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats.
    Toxicology, 2007, Feb-12, Volume: 230, Issue:2-3

    Topics: Acetylglucosaminidase; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; bet

2007
Cardioprotective effect of squalene on lipid profile in isoprenaline-induced myocardial infarction in rats.
    Journal of medicinal food, 2006,Winter, Volume: 9, Issue:4

    Topics: Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Fatty Acids, Nonesterified; Isoproterenol;

2006
Ethanolic Zingiber officinale R. extract pretreatment alleviates isoproterenol-induced oxidative myocardial necrosis in rats.
    Indian journal of experimental biology, 2006, Volume: 44, Issue:11

    Topics: Animals; Antioxidants; Biomarkers; Ethanol; Female; Isoproterenol; Lipid Peroxidation; Male; Myocard

2006
Influence of ovariectomy in the right ventricular contractility in heart failure rats.
    Archives of medical research, 2007, Volume: 38, Issue:2

    Topics: Animals; Cardiac Output, Low; Cardiotonic Agents; Estrogens; Female; Heart Ventricles; Isoproterenol

2007
Protective effect of n-3 polyunsaturated fatty acids concentrate on isoproterenol-induced myocardial infarction in rats.
    Prostaglandins, leukotrienes, and essential fatty acids, 2007, Volume: 76, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardiotonic Agents; Cholesterol; Cholest

2007
Preventive effect of naringin on isoproterenol-induced cardiotoxicity in Wistar rats: an in vivo and in vitro study.
    Toxicology, 2007, Apr-11, Volume: 232, Issue:3

    Topics: Animals; Benzothiazoles; Biphenyl Compounds; Blood Glucose; Ca(2+) Mg(2+)-ATPase; Calcium-Transporti

2007
Preventive effect of rutin on lipids, lipoproteins, and ATPases in normal and isoproterenol-induced myocardial infarction in rats.
    Journal of biochemical and molecular toxicology, 2007, Volume: 21, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Cholesterol;

2007
Enhanced beta-adrenergic response in rat papillary muscle by inhibition of inducible nitric oxide synthase after myocardial infarction.
    Acta physiologica (Oxford, England), 2007, Volume: 190, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Isoprotereno

2007
Cardioprotective effect of Azadirachta indica A. Juss. on isoprenaline induced myocardial infarction in rats.
    International journal of cardiology, 2008, May-07, Volume: 126, Issue:1

    Topics: Animals; Azadirachta; Cardiotonic Agents; Isoproterenol; Male; Myocardial Infarction; Plant Extracts

2008
Preventive effect of S-allyl cysteine sulfoxide (alliin) on lysosomal hydrolases and membrane-bound ATPases in isoproterenol-induced myocardial infarction in Wistar rats.
    Journal of biochemical and molecular toxicology, 2007, Volume: 21, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Cell Membrane; Cysteine; Enzyme Activation; Hydrolases; Isoprote

2007
Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channels, L-Type; Calcium Signaling; C

2007
Troponin T and histological characteristics of rat myocardial infarction induced by isoproterenol.
    Bosnian journal of basic medical sciences, 2007, Volume: 7, Issue:3

    Topics: Animals; Body Weight; Cardiotonic Agents; Creatine Kinase; Heart; Isoproterenol; Male; Myocardial In

2007
Susceptibility to systolic dysfunction in the myocardium from chronically infarcted spontaneously hypertensive rats.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1

    Topics: Animals; Apoptosis; Cardiotonic Agents; Coronary Vessels; Disease Models, Animal; Hypertension; Isop

2008
Cardioprotective effect of alpha-mangostin, a xanthone derivative from mangosteen on tissue defense system against isoproterenol-induced myocardial infarction in rats.
    Journal of biochemical and molecular toxicology, 2007, Volume: 21, Issue:6

    Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Garcinia mangostana; Isoproterenol; Lipid Per

2007
Preventive effect of naringin on cardiac mitochondrial enzymes during isoproterenol-induced myocardial infarction in rats: a transmission electron microscopic study.
    Journal of biochemical and molecular toxicology, 2007, Volume: 21, Issue:6

    Topics: Animals; Cardiotonic Agents; Flavanones; Isoproterenol; Male; Microscopy, Electron, Transmission; Mi

2007
Protective effect of (-)-epigallocatechin-gallate (EGCG) on lipid peroxide metabolism in isoproterenol induced myocardial infarction in male Wistar rats: a histopathological study.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2008, Volume: 62, Issue:10

    Topics: Animals; Catechin; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction; Myocardium; Rats;

2008
Exercise promotes angiogenesis and improves beta-adrenergic receptor signalling in the post-ischaemic failing rat heart.
    Cardiovascular research, 2008, May-01, Volume: 78, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Coronary Circulation; Coronary Vessels; Disease Models, Animal; D

2008
Protective effect of S-allyl cysteine sulphoxide (alliin) on glycoproteins and hematology in isoproterenol induced myocardial infarction in male Wistar rats.
    Journal of applied toxicology : JAT, 2008, Volume: 28, Issue:5

    Topics: Adrenergic beta-Agonists; Animals; Blood Cell Count; Blood Chemical Analysis; Blood Coagulation; Car

2008
(-)-Epigallocatechin gallate (EGCG) prevents isoprenaline-induced cardiac marker enzymes and membrane-bound ATPases.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:1

    Topics: Adenosine Triphosphatases; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; C

2008
Preventive effect of (-)epigallocatechin-gallate (EGCG) on lysosomal enzymes in heart and subcellular fractions in isoproterenol-induced myocardial infarcted Wistar rats.
    Chemico-biological interactions, 2008, Apr-15, Volume: 172, Issue:3

    Topics: Animals; Cardiovascular Agents; Catechin; Disease Models, Animal; Heart; Isoproterenol; Lysosomes; M

2008
Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress.
    Circulation, 2008, Mar-18, Volume: 117, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Cells, Cultured; GTP-Binding Protein alpha Subunit, Gi

2008
Isoproterenol-induced cardiotoxicity in sprague-dawley rats: correlation of reversible and irreversible myocardial injury with release of cardiac troponin T and roles of iNOS in myocardial injury.
    Toxicologic pathology, 2008, Volume: 36, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Apoptosis; Cell Count; Disease Models, Animal; Dose-Response R

2008
Electrocardiography in two models of isoproterenol-induced left ventricular remodeling.
    Physiological research, 2008, Volume: 57 Suppl 2

    Topics: Action Potentials; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiog

2008
Protective role of curcumin in myocardial oxidative damage induced by isoproterenol in rats.
    Human & experimental toxicology, 2007, Volume: 26, Issue:12

    Topics: Adrenergic beta-Agonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardiotonic Ag

2007
Cardioprotective effect of fluvastatin on isoproterenol-induced myocardial infarction in rat.
    European journal of pharmacology, 2008, May-31, Volume: 586, Issue:1-3

    Topics: Adrenergic beta-Agonists; Animals; Antioxidants; Body Weight; Electrocardiography; Fatty Acids, Mono

2008
Protective effects of N-acetylcysteine in isoproterenol-induced myocardium injury in rats.
    Molecular biology reports, 2009, Volume: 36, Issue:4

    Topics: Acetylcysteine; Animals; Creatine Kinase, MB Form; Cytokines; Gene Expression Regulation; Isoprotere

2009
Temporal gene expression profiling indicates early up-regulation of interleukin-6 in isoproterenol-induced myocardial necrosis in rat.
    Toxicologic pathology, 2008, Volume: 36, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Disease Models, Animal; Gene Expression Profiling; Heart; Injecti

2008
New aspects of cyclooxygenase-2 inhibition in myocardial infarction and ischaemia.
    Research communications in molecular pathology and pharmacology, 2005, Volume: 117-118

    Topics: Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Creatine Kinase; Cyclooxygenase 2; Cyclooxyge

2005
(-)Epigallocatechin-gallate (EGCG) prevents mitochondrial damage in isoproterenol-induced cardiac toxicity in albino Wistar rats: a transmission electron microscopic and in vitro study.
    Pharmacological research, 2008, Volume: 57, Issue:5

    Topics: Animals; Antioxidants; Catalase; Catechin; Free Radical Scavengers; Glutathione; In Vitro Techniques

2008
Haemodynamic effects of propranolol.
    British medical journal, 1967, Apr-15, Volume: 2, Issue:5545

    Topics: Adult; Aged; Atropine; Heart Rate; Humans; Hypertension; Isoproterenol; Middle Aged; Myocardial Infa

1967
Left ventricular contraction and the therapy of cardiogenic shock.
    Circulation, 1967, Volume: 35, Issue:4

    Topics: Blood Flow Velocity; Blood Pressure; Blood Viscosity; Blood Volume; Cardiac Output; Dextrans; Digita

1967
Isoproterenol conversion of tachyarrhythmia during acute myocardial infarction.
    Southern medical journal, 1967, Volume: 60, Issue:6

    Topics: Electric Countershock; Electrocardiography; Humans; Injections, Intravenous; Isoproterenol; Male; Mi

1967
Cardiomyopathies.
    Science (New York, N.Y.), 1967, Jun-23, Volume: 156, Issue:3782

    Topics: Brain Diseases; Cardiomyopathies; Electrolytes; Isoproterenol; Myocardial Infarction; Myocarditis; N

1967
Hemodynamic studies in cardiogenic shock. Treatment with isoproterenol and metaraminol.
    Circulation, 1967, Volume: 35, Issue:6

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Electrocardiography; Female; Hemodynamics; Humans; Hypo

1967
Effect of isoproterenol and norepinephrine on myocardial function in experimental cardiogenic shock.
    American heart journal, 1967, Volume: 74, Issue:3

    Topics: Animals; Blood Pressure; Coronary Vessels; Dogs; Heart Rate; Isoproterenol; Lactates; Myocardial Inf

1967
Changing treatment of shock following acute myocardial infarction--a critical evaluation.
    The American journal of cardiology, 1967, Volume: 20, Issue:6

    Topics: Acute Disease; Assisted Circulation; Digitalis; Hemodynamics; Humans; Isoproterenol; Myocardial Infa

1967
[Resuscitation in the auriculo-ventricular block of acute myocardial infarct].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1967, Jun-16, Volume: 118, Issue:10

    Topics: Electric Countershock; Glucocorticoids; Heart Block; Humans; Isoproterenol; Myocardial Infarction

1967
Treatment of arrhythmias following myocardial infarction.
    The Journal of the Indiana State Medical Association, 1967, Volume: 60, Issue:8

    Topics: Arrhythmias, Cardiac; Digitalis; Electric Countershock; Humans; Isoproterenol; Lidocaine; Metaramino

1967
The coronary care unit. A year's experience in a community hospital.
    JAMA, 1967, Aug-28, Volume: 201, Issue:9

    Topics: Aged; Anticoagulants; Atropine; Bradycardia; Community Health Services; Diet Therapy; Digitalis Glyc

1967
Ineffectiveness of isoproterenol in shock due to acute myocardial infarction.
    JAMA, 1967, Dec-25, Volume: 202, Issue:13

    Topics: Aged; Arteries; Blood Pressure; Cardiac Output; Female; Humans; Isoproterenol; Male; Middle Aged; My

1967
The treatment of cardiogenic shock. 3. The use of isoproterenol in cardiogenic shock.
    American heart journal, 1967, Volume: 74, Issue:6

    Topics: Aged; Hemodynamics; Humans; Isoproterenol; Middle Aged; Myocardial Infarction; Shock

1967
Impaired beta-adrenergic stimulation in the uninvolved ventricle post-acute myocardial infarction: reversible defect due to excessive circulating catecholamine-induced decline in number and affinity of beta-receptors.
    American heart journal, 1981, Volume: 101, Issue:5

    Topics: Adenylyl Cyclases; Animals; Catecholamines; Coronary Circulation; Female; Guinea Pigs; Isoproterenol

1981
Cardiac contractile and metabolic effects mediated via the myocardial H2-receptor adenylate cyclase system. Characterization of two new specific H2-receptor agonists, impromidine and dimaprit, in the guinea pig and human myocardium.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1981, Volume: 179, Issue:1

    Topics: Adenylyl Cyclases; Animals; Cimetidine; Cyclic AMP; Dimaprit; Dose-Response Relationship, Drug; Fema

1981
Effects of sulfinpyrazone, aspirin and propranolol on the isoproterenol-induced myocardial necrosis.
    Japanese heart journal, 1981, Volume: 22, Issue:4

    Topics: Animals; Aspirin; Body Weight; Creatine Kinase; Cyclic AMP; Heart; Isoproterenol; Male; Myocardial I

1981
An overall review on prenylamine mechanisms of action in experimental models of myocardial damage.
    Cardiology, 1982, Volume: 69, Issue:4

    Topics: Angina Pectoris; Animals; Calcium; Cebus; Disease Models, Animal; Electrocardiography; Female; Heart

1982
Modification of "depressed fast channel dependent slow conduction" by lidocaine and verapamil in the presence or absence of catecholamines--evidence for alteration of preferential ionic channels for slow conduction.
    Japanese circulation journal, 1983, Volume: 47, Issue:1

    Topics: Action Potentials; Animals; Catecholamines; Guinea Pigs; Heart Conduction System; In Vitro Technique

1983
Ventricular fibrillation threshold and myocardial cyclic AMP production in rats sensitive or resistant to isoproterenol.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 44, Issue:2

    Topics: Animals; Cyclic AMP; Drug Resistance; Electrocardiography; Isoproterenol; Male; Myocardial Infarctio

1984
Management of acute myocardial infarction with natural physiological agents.
    Medical hypotheses, 1983, Volume: 11, Issue:4

    Topics: Acute Disease; Adenosine; Animals; Carnitine; Collateral Circulation; Dipyridamole; Dogs; Epoprosten

1983
Ribose prevents the propranolol-induced reduction of myocardial adenine nucleotide biosynthesis.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt B

    Topics: Adenine Nucleotides; Animals; Female; Heart; Isoproterenol; Myocardial Infarction; Myocardium; Propr

1984
Myocardial hypertrophy in the rat. Correlation between two experimental models.
    Japanese heart journal, 1980, Volume: 21, Issue:4

    Topics: Animals; Cardiomegaly; Disease Models, Animal; Heart; Hypoxia; Isoproterenol; Male; Myocardial Infar

1980
Repetitive, monomorphic ventricular tachycardia: clinical and electrophysiologic characteristics in patients with and patients without organic heart disease.
    The American journal of cardiology, 1984, Nov-01, Volume: 54, Issue:8

    Topics: Adolescent; Adult; Aged; Cardiac Pacing, Artificial; Electrocardiography; Exercise Test; Female; Hum

1984
Depletion of myocardial potassium as a function of age and experimental necrosis.
    Indian journal of experimental biology, 1984, Volume: 22, Issue:3

    Topics: Aging; Animals; Female; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Potassium; Rats;

1984
Newer concepts in the pathophysiology of ischemic heart disease.
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:11

    Topics: Animals; Coronary Circulation; Coronary Disease; Creatine Kinase; Dogs; Heart Rate; Humans; Isoprote

1984
Effect of experimental infarct on the mortality rate in alloxan-diabetic rats.
    Experimental pathology, 1984, Volume: 25, Issue:2

    Topics: Alloxan; Animals; Creatine Kinase; Diabetes Mellitus, Experimental; Insulin, Long-Acting; Isoprotere

1984
Pharmacological studies on propafenone and its main metabolite 5-hydroxypropafenone.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:11

    Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Calcium Channel Blockers; Dogs

1984
Changes in soluble and insoluble glycoproteins in isoproterenol-induced myocardial infarction in rats.
    Indian journal of biochemistry & biophysics, 1984, Volume: 21, Issue:6

    Topics: Animals; Female; Glycoproteins; Isoproterenol; Myocardial Infarction; Rats; Rats, Inbred Strains; So

1984
[Effect of essential oil of Litsea eubeba (LOUR.) Pers on experimental myocardial infarction in rabbits and myocardial necrosis induced by isoprenaline in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1983, Volume: 18, Issue:5

    Topics: Animals; China; Electrocardiography; Fatty Acids, Nonesterified; Female; Isoproterenol; Male; Myocar

1983
Effect of ethanol administration on changes in metabolism of glycosaminoglycans in heart & aorta in isoproterenol-induced myocardial infarction in rats.
    Indian journal of biochemistry & biophysics, 1983, Volume: 20, Issue:5

    Topics: Animals; Aorta; Ethanol; Glycosaminoglycans; Isoproterenol; Male; Myocardial Infarction; Myocardium;

1983
Effect of ethanol administration on changes in the metabolism of glycoproteins in the heart produced in isoproterenol induced myocardial infarction in rats.
    Indian journal of experimental biology, 1983, Volume: 21, Issue:11

    Topics: Animals; Ethanol; Glycoproteins; Heart; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats

1983
An ultrastructural study of endocardial endothelium alterations in catecholamine-induced infarct-like necrosis.
    Revue canadienne de biologie experimentale, 1983, Volume: 42, Issue:1

    Topics: Animals; Endocardium; Endothelium; Isoproterenol; Male; Microscopy, Electron; Microscopy, Electron,

1983
Effects of amrinone on experimental acute myocardial ischaemic injury.
    Cardiovascular research, 1980, Volume: 14, Issue:7

    Topics: Aminopyridines; Amrinone; Animals; Carbon Dioxide; Cardiotonic Agents; Dogs; Electrocardiography; He

1980
Effects of antiplatelet and calcium antagonist drugs on infarct size in rats.
    Acta cardiologica, 1980, Volume: 35, Issue:6

    Topics: Acute Disease; Animals; Aspirin; Blood Platelets; Calcium; Creatine Kinase; Isoproterenol; Lysine; M

1980
Detection of acute myocardial infarction in spontaneously hypertensive rats by 99mTc-pyrrolidino methyl tetracycline.
    European journal of nuclear medicine, 1983, Volume: 8, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Hypertension; Isoproterenol; Male; Myocardial Infarction; M

1983
Mesenteric blood flow response to dopamine infusion during myocardial infarction in the awake dog.
    Circulatory shock, 1983, Volume: 10, Issue:2

    Topics: Animals; Blood Flow Velocity; Dogs; Dopamine; Infusions, Intra-Arterial; Isoproterenol; Myocardial I

1983
Hormonal and metabolic changes during acute myocardial infarction in normotensive vs hypertensive rats.
    British journal of experimental pathology, 1983, Volume: 64, Issue:2

    Topics: Animals; Body Weight; Bromocriptine; Electrocardiography; Female; Heart Rate; Hormones; Hypertension

1983
Reperfusion injury. A possible link between catecholamine-induced and ischemic myocardial alterations.
    Advances in myocardiology, 1983, Volume: 4

    Topics: Animals; Catecholamines; Cell Membrane Permeability; Coronary Circulation; Coronary Disease; Horsera

1983
Comparative effects of acetylsalicylic acid (ASA) and sulfinpyrazone on isoproterenol-induced heart damage.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Urea Nitrogen; Creatine Kinase; Isoproterenol;

1981
Morphological variants of acute myocardial necrosis and their relationship to coronary artery thrombosis.
    Acta medica Scandinavica. Supplementum, 1980, Volume: 642

    Topics: Animals; Arteriosclerosis; Coronary Disease; Coronary Vessels; Fibrinogen; Humans; Isoproterenol; My

1980
Uptake of 67Ga in the heart of rats treated with isoproterenol.
    European journal of nuclear medicine, 1982, Volume: 7, Issue:12

    Topics: Animals; Aspartate Aminotransferases; Creatine Kinase; Gallium Radioisotopes; Glucosephosphate Dehyd

1982
Elevated blood taurine levels after myocardial infarction of cardiovascular surgery: is there any significance?
    Advances in experimental medicine and biology, 1981, Volume: 139

    Topics: Animals; Cardiac Surgical Procedures; Coronary Artery Bypass; Creatine Kinase; Dogs; Heart; Humans;

1981
Newer concepts in the pathophysiology of ischemic heart disease.
    American heart journal, 1982, Volume: 103, Issue:4 Pt 2

    Topics: Animals; Cardiac Glycosides; Collateral Circulation; Coronary Circulation; Coronary Disease; Dogs; H

1982
Method for evaluating the effects of antiarrhythmic drugs on ventricular tachycardias with different electrophysiologic characteristics and different mechanisms in the infarcted canine heart.
    The American journal of cardiology, 1982, Apr-01, Volume: 49, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Dogs; Electrophysiology; Female; Isopro

1982
Beneficial effects of exercise on l-isoproterenol induced myocardial infarction in male rats.
    Medicine and science in sports and exercise, 1982, Volume: 14, Issue:1

    Topics: Animals; Electrocardiography; Exercise Therapy; Isoproterenol; Male; Myocardial Infarction; Rats; Ra

1982
Changes in glycoproteins in isoproterenol-induced myocardial infarction in rats.
    Indian journal of biochemistry & biophysics, 1982, Volume: 19, Issue:1

    Topics: Animals; Disease Models, Animal; Glycoproteins; Isoproterenol; Male; Myocardial Infarction; Myocardi

1982
[Enhancing hemodynamic effect of intraaortic balloon pumping (IABP) using cardiogenic agents in canine myocardial infarction].
    Rinsho kyobu geka = Japanese annals of thoracic surgery, 1982, Volume: 2, Issue:4

    Topics: Animals; Assisted Circulation; Dipyridamole; Dogs; Hemodynamics; Intra-Aortic Balloon Pumping; Isopr

1982
Quantitative assessment of infarct size in isoproterenol-infarcted rats.
    Japanese heart journal, 1982, Volume: 23, Issue:6

    Topics: Animals; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats; Rats, Inbred Strains

1982
Effect of norepinephrine on isolated coronary artery of normal and myocardial infarcted pigs.
    Artery, 1982, Volume: 10, Issue:5

    Topics: Animals; Arteries; Coronary Vessels; Epinephrine; Isoproterenol; Myocardial Infarction; Norepinephri

1982
Effect of indigenous drug (Pushkarmula) on experimentally induced myocardial infarction in rats.
    Activitas nervosa superior, 1982, Volume: Suppl 3, Issue:Pt 2

    Topics: Animals; Inula; Inulin; Isoproterenol; Male; Medicine, Ayurvedic; Myocardial Infarction; Plant Extra

1982
Metabolism of glycosaminoglycans in the heart of rats subjected to isoproterenol-induced myocardial infarction.
    Indian journal of biochemistry & biophysics, 1982, Volume: 19, Issue:5

    Topics: Animals; Glycosaminoglycans; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats; Rats, Inb

1982
Relative role of caloric restriction and exercise training upon susceptibility to isoproterenol-induced myocardial infarction in male rats.
    The American journal of clinical nutrition, 1981, Volume: 34, Issue:5

    Topics: Animals; Aspartate Aminotransferases; Body Weight; Creatine Kinase; Diet, Reducing; Isoproterenol; L

1981
Allopurinol amelioration of the pathophysiology of acute myocardial infarction in rats.
    Atherosclerosis, 1981, Volume: 39, Issue:1

    Topics: Allopurinol; Animals; Isoproterenol; Male; Myocardial Infarction; Rats

1981
Reduction in the severity of myocardial infarction by sulfinpyrazone.
    American heart journal, 1981, Volume: 102, Issue:2

    Topics: Animals; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats; Sulfinpyrazone

1981
Abnormal electrocardiographic activity revealed by isolated rat heart preparations at various times after experimental myocardial infarction.
    Cardiovascular research, 1981, Volume: 15, Issue:3

    Topics: Animals; Electrocardiography; In Vitro Techniques; Isoproterenol; Male; Myocardial Infarction; Myoca

1981
Changes in myocardial & aortic lipids, lipolytic activity & fecal excretion of sterols & bile acids in isoproterenol-induced myocardial infarction in rats.
    Indian journal of biochemistry & biophysics, 1981, Volume: 18, Issue:2

    Topics: Animals; Aorta; Bile Acids and Salts; Feces; Female; Heart; Isoproterenol; Lipase; Lipid Metabolism;

1981
Effect of perhexilene on 86Rb uptake in experimental myocardial infarction.
    Indian journal of experimental biology, 1981, Volume: 19, Issue:8

    Topics: Animals; Biological Transport, Active; Disease Models, Animal; Female; Heart; Isoproterenol; Male; M

1981
Changes in the magnesium content of tissues following myocardial damage in rats.
    Medical biology, 1981, Volume: 59, Issue:2

    Topics: Animals; Isoproterenol; Magnesium; Male; Myocardial Infarction; Rats; Tissue Distribution

1981
[Determination of tissue creatine phosphokinase as a direct enzymatic method for evaluation of the area of necrosis in rats with isoproterenol-induced infarctions].
    Minerva cardioangiologica, 1981, Volume: 29, Issue:11

    Topics: Animals; Creatine Kinase; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Rats; Rats, In

1981
Transient tachycardia- and bradycardia-dependent left anterior and left posterior hemiblocks. Effects of isoproterenol.
    International journal of cardiology, 1981, Volume: 1, Issue:1

    Topics: Aged; Bradycardia; Bundle-Branch Block; Electrocardiography; Female; Humans; Isoproterenol; Male; My

1981
[Effect of nifedipine on experimental myocardial infarct induced by isoproterenol].
    Bollettino della Societa italiana di cardiologia, 1981, Volume: 26, Issue:11

    Topics: Animals; Isoproterenol; Myocardial Infarction; Nifedipine; Pyridines; Rats; Rats, Inbred Strains

1981
Effect of phenelzine, a monoamine oxidase inhibitor, on isoproterenol-induced myocardial damage.
    Advances in myocardiology, 1980, Volume: 2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Heart; Isoproterenol; Male; Myocardial I

1980
Effect of extent of myocardial damage on the behavior of myocardial zinc in albino rats.
    Advances in myocardiology, 1980, Volume: 2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Heart; Isoproterenol; L-Lactate Dehydrog

1980
[Comparative study using colloidal lanthanum of defects in cardiomyocyte membrane permeability in deep ischemia and in isoproterenol exposure].
    Arkhiv patologii, 1980, Volume: 42, Issue:10

    Topics: Animals; Cell Membrane Permeability; Colloids; Coronary Disease; Dogs; Isoproterenol; Lanthanum; Mic

1980
[Isoproterenol induces ST-segment elevation without wall motion aggravation and myocardial ischemia in experimental myocardial infarction].
    Journal of cardiology, 1995, Volume: 26, Issue:3

    Topics: Animals; Cardiotonic Agents; Coronary Circulation; Dogs; Electrocardiography; Female; Hemodynamics;

1995
Effect of interventions that increase cyclic AMP levels on susceptibility to ventricular fibrillation in unanesthetized dogs.
    European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Anesthesia;

1994
[Ca2+]i transients in hypertensive and postinfarction myocytes.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 1

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiac Pacing, Artificial; Cell Separation; Diastole; F

1995
Relation between myocardial beta-adrenoceptor density and hemodynamic and neurohumoral changes in a rat model of chronic myocardial infarction: effects of ibopamine and captopril.
    Cardiovascular research, 1995, Volume: 30, Issue:3

    Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chronic Dise

1995
Effect of nitrendipine, nimodipine and nisoldipine on experimentally induced myocardial infarction in rats.
    Indian journal of experimental biology, 1995, Volume: 33, Issue:6

    Topics: Animals; Aspartate Aminotransferases; Calcium Channel Blockers; Female; Heart; Isoproterenol; L-Lact

1995
Oligotide, a new single-stranded oligodeoxyribonucleotide, preserves postsynaptic beta-adrenergic and cholinergic receptor functions in rabbit hearts after acute infarction.
    Thrombosis research, 1995, Jun-01, Volume: 78, Issue:5

    Topics: Acetylcholine; Animals; Drug Evaluation, Preclinical; Endothelium, Vascular; Epoprostenol; Infusions

1995
Effect of isoproterenol on serum potassium and magnesium.
    European heart journal, 1993, Volume: 14, Issue:5

    Topics: Adult; Aged; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Cardiomyopathy, Dilated; Diag

1993
Characteristics of the beta-adrenergic receptor complex in the epicardial border zone of the 5-day infarcted canine heart.
    Circulation, 1995, Jun-01, Volume: 91, Issue:11

    Topics: Adenylyl Cyclases; Animals; Dogs; Female; GTP-Binding Proteins; Immunoblotting; Iodocyanopindolol; I

1995
Isoproterenol-induced redistribution of endosomes in cardiac myocytes.
    European journal of cell biology, 1994, Volume: 65, Issue:1

    Topics: Animals; Cells, Cultured; Endosomes; Frozen Sections; Heart; Hydrogen-Ion Concentration; Immunohisto

1994
Effects of catecholamines on the residual sodium channel dependent slow conduction in guinea pig ventricular muscles under normoxia and hypoxia.
    Cardiovascular research, 1995, Volume: 29, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Channels; Catecholamines; Dose-Response Re

1995
Effects of oxodipine and nitrendipine on the size of experimental myocardial infarct in the rat.
    Pharmacology & toxicology, 1994, Volume: 74, Issue:6

    Topics: Administration, Oral; Animals; Calcium Channel Blockers; Dihydropyridines; Female; Heart; Isoprotere

1994
Effects of metoprolol on left ventricular function in rats with myocardial infarction.
    The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2

    Topics: Animals; Blood Pressure; Coronary Vessels; Diastole; Disease Models, Animal; Dose-Response Relations

1994
Regional myocardial downregulation of the inhibitory guanosine triphosphate-binding protein (Gi alpha 2) and beta-adrenergic receptors in a porcine model of chronic episodic myocardial ischemia.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:6

    Topics: Adenylyl Cyclases; Animals; Base Sequence; Cell Membrane; Coronary Circulation; Disease Models, Anim

1993
Collagen levels in isoproterenol induced myocardial infarction in rats.
    Indian journal of experimental biology, 1993, Volume: 31, Issue:10

    Topics: Animals; Collagen; Female; Isoproterenol; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Tim

1993
[Changes in myocardial metallothionein on isoproterenol-induced myocardial injury].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1993, Volume: 113, Issue:8

    Topics: Animals; Copper; Isoproterenol; Male; Metallothionein; Myocardial Infarction; Myocardium; Rats; Rats

1993
Effect of aspirin on mitochondrial lipids in experimental myocardial infarction in rats.
    Biochemistry and molecular biology international, 1993, Volume: 29, Issue:5

    Topics: Administration, Oral; Animals; Aspirin; Calcium-Transporting ATPases; Cholesterol; Fatty Acids; Isop

1993
Effect of curcumin on certain lysosomal hydrolases in isoproterenol-induced myocardial infarction in rats.
    Biochemical pharmacology, 1996, Jan-12, Volume: 51, Issue:1

    Topics: Animals; Cathepsin D; Curcumin; Female; Intracellular Membranes; Isoproterenol; Lysosomes; Myocardia

1996
Calcium currents in postinfarction rat cardiac myocytes.
    The American journal of physiology, 1995, Volume: 269, Issue:6 Pt 1

    Topics: Animals; Calcium; Dihydropyridines; Electric Conductivity; Heart; Isoproterenol; Isradipine; Male; M

1995
Diminished responsiveness to cardiac beta 1-adrenoceptor agonists in rats with chronic heart failure following myocardial infarction.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:10

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Animals; Cardiac Output; Chronic Dise

1995
Altered pharmacologic responsiveness of reduced L-type calcium currents in myocytes surviving in the infarcted heart.
    Journal of cardiovascular electrophysiology, 1996, Volume: 7, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1996
Angiotensin II and contraction of isolated myocytes from human, guinea pig, and infarcted rat hearts.
    The American journal of physiology, 1996, Volume: 270, Issue:6 Pt 2

    Topics: Adult; Aged; Angiotensin II; Animals; Cell Separation; Female; Guinea Pigs; Humans; Isoenzymes; Isop

1996
Protective role of curcumin against isoproterenol induced myocardial infarction in rats.
    Molecular and cellular biochemistry, 1996, Jun-21, Volume: 159, Issue:2

    Topics: Animals; Antioxidants; Cell Membrane; Creatine Kinase; Curcumin; Electrocardiography; Female; Glutat

1996
Influence of cardiac dysfunction on fast sodium current regulation by Forskolin.
    Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:11 Pt 2

    Topics: Action Potentials; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cardiotonic Agents; Colfors

1996
Impairment of cGMP- and cAMP-mediated vasorelaxations in rats with chronic heart failure.
    The American journal of physiology, 1996, Volume: 271, Issue:6 Pt 2

    Topics: Animals; Aorta, Thoracic; Cardiac Output, Low; Chronic Disease; Cyclic AMP; Cyclic GMP; Enzyme Inhib

1996
Differential regulation of natriuretic peptide genes in infarcted rat hearts.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:1

    Topics: Animals; Atrial Natriuretic Factor; Creatine Kinase; Disease Models, Animal; Gene Expression Regulat

1997
Effect of alpha-tocopherol on isoproterenol induced myocardial infarction in rats--electrocardiographic biochemical and histological evidences.
    Indian journal of physiology and pharmacology, 1996, Volume: 40, Issue:4

    Topics: Animals; Aorta; Cardiotonic Agents; Drug Interactions; Electrocardiography; Heart Rate; Isoprotereno

1996
Usefulness of isoproterenol in the induction of clinical sustained ventricular tachycardia during electrophysiological study.
    Acta cardiologica, 1997, Volume: 52, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Atenolol; Cardiac Pacing, Artificial; E

1997
Autonomic effects on noise recorded during signal-averaged electrocardiography.
    Pacing and clinical electrophysiology : PACE, 1997, Volume: 20, Issue:7

    Topics: Adrenergic alpha-Agonists; Adrenergic Antagonists; Adrenergic beta-Antagonists; Adult; Artifacts; At

1997
Myocardial infarction and regulatory myosin light chain.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:10

    Topics: Animals; Calcium; Calmodulin; Cardiotonic Agents; Cell Survival; Coronary Vessels; Heart Rate; Isopr

1997
Low-dose aspirin improves in vivo hemodynamics in conscious, chronically infarcted rats.
    Cardiovascular research, 1998, Volume: 37, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Aspirin; Drug Administration Schedule; Heart Rate; Hemodynamics;

1998
Sequential changes of energy metabolism and mitochondrial function in myocardial infarction induced by isoproterenol in rats: a long-term and integrative study.
    Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:12

    Topics: Animals; Blood Pressure; Cardiotonic Agents; Edema; Electrophysiology; Energy Metabolism; Heart; Hea

1997
Porphyrin loading of lipofuscin granules in inflamed striated muscle.
    The American journal of pathology, 1998, Volume: 153, Issue:3

    Topics: Animals; Coproporphyrins; Cytoplasmic Granules; Fluorescence; Humans; Image Processing, Computer-Ass

1998
Effect of alpha-tocopherol on mitochondrial electron transport in experimental myocardial infarction in rats.
    Indian journal of biochemistry & biophysics, 1998, Volume: 35, Issue:2

    Topics: Animals; Citric Acid Cycle; Cytochromes; Electron Transport; Isoproterenol; Lipid Peroxidation; Lipi

1998
Effect of alpha-tocopherol on lipid peroxidation in isoproterenol induced myocardial infarction in rats.
    Indian journal of physiology and pharmacology, 1997, Volume: 41, Issue:4

    Topics: Animals; Antioxidants; Free Radicals; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction

1997
Desensitization of cardiac beta-adrenoceptor signaling with heart failure produced by myocardial infarction in the rat. Evidence for the role of Gi but not Gs or phosphorylating proteins.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:6

    Topics: Adrenergic beta-Agonists; Animals; Arrestins; Autoradiography; beta-Adrenergic Receptor Kinases; bet

1999
Antioxidant activity of AO-8, a herbal formulation in vitro and in vivo experimental models.
    Phytotherapy research : PTR, 1999, Volume: 13, Issue:4

    Topics: Animals; Antioxidants; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Free

1999
Effects of propranolol treatment on left ventricular function and intracellular calcium regulation in rats with postinfarction heart failure.
    British journal of pharmacology, 1999, Volume: 127, Issue:7

    Topics: Adrenergic beta-Antagonists; Aequorin; Animals; Calcium; Cardiotonic Agents; Coronary Circulation; E

1999
Inducible nitric oxide synthase and tumor necrosis factor in animal models of myocardial necrosis induced by coronary artery ligation or isoproterenol injection.
    Journal of cardiac failure, 1999, Volume: 5, Issue:3

    Topics: Animals; Biomarkers; Blotting, Northern; Coronary Vessels; Disease Models, Animal; Heart Ventricles;

1999
Ionic basis of ventricular arrhythmias in remodeled rat heart during long-term myocardial infarction.
    Cardiovascular research, 1999, Volume: 42, Issue:2

    Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animal

1999
Effects of endothelial and inducible nitric oxide synthases inhibition on circulatory function in rats after myocardial infarction.
    Cardiovascular research, 1999, Volume: 42, Issue:3

    Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Enzyme In

1999
Differential effects of mibefradil, verapamil, and amlodipine on myocardial function and intracellular Ca(2+) handling in rats with chronic myocardial infarction.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Adrenergic beta-Agonists; Aequorin; Amlodipine; Animals; Calcium; Calcium Channel Blockers; Chronic

1999
Effects of the calcium channel antagonist mibefradil on haemodynamic parameters and myocardial Ca(2+)-handling in infarct-induced heart failure in rats.
    Cardiovascular research, 1999, Volume: 44, Issue:1

    Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Blood Pressure; Calcium; Calcium Channel Bl

1999
Cardioprotective effect of magnesium chloride in experimental acute myocardial infarction.
    Indian journal of experimental biology, 1999, Volume: 37, Issue:2

    Topics: Animals; Calcium Channel Blockers; Cardiovascular Agents; Creatine Kinase; Female; Isoproterenol; Ma

1999
Na(+)/H(+) exchange inhibition attenuates hypertrophy and heart failure in 1-wk postinfarction rat myocardium.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Cardiac Output, Low; Cardiomegaly; Guanidines; Hemodynamics; Isop

2000
Inducible nitric oxide synthase activation after ischemia/reperfusion contributes to myocardial dysfunction and extent of infarct size in rabbits: evidence for a late phase of nitric oxide-mediated reperfusion injury.
    Cardiovascular research, 1999, Aug-15, Volume: 43, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Enzyme Activation; Enzyme Inhibitors; Guanidines; Hemodynamics; I

1999
Comparison of isoproterenol-induced changes in lysosomal enzyme activity in vivo and in vitro.
    General physiology and biophysics, 1999, Volume: 18 Spec No

    Topics: Acetylglucosaminidase; Acid Phosphatase; Animals; Carcinoma, Hepatocellular; Cathepsin D; Glucuronid

1999
Reduction of infarct size by selective stimulation of prostaglandin EP(3)receptors in the reperfused ischemic pig heart.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:2

    Topics: Action Potentials; Adenylyl Cyclases; Adrenergic beta-Agonists; Alprostadil; Animals; Arrhythmias, C

2000
Altered cardiac collagen and associated changes in diastolic function of infarcted rat hearts.
    Cardiovascular research, 2000, Volume: 46, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal

2000
beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling.
    Circulation, 2000, May-02, Volume: 101, Issue:17

    Topics: Adrenergic beta-Antagonists; Animals; Cytokines; Gene Expression; Interleukin-1; Interleukin-6; Isop

2000
[A patient with myocardial infarction loosing her sight].
    Duodecim; laaketieteellinen aikakauskirja, 1997, Volume: 113, Issue:22

    Topics: Aged; Epinephrine; Female; Glaucoma, Angle-Closure; Humans; Isoproterenol; Myocardial Infarction; Sy

1997
Dyssynchronous Ca(2+) sparks in myocytes from infarcted hearts.
    Circulation research, 2000, Nov-24, Volume: 87, Issue:11

    Topics: Action Potentials; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channels, L-Type; Calcium Sig

2000
Vascular beta-adrenergic receptor system is dysfunctional after myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Aorta; Aurora Kinases; Blood Pressur

2001
Cardioprotective effects of Picrorrhiza kurroa against isoproterenol-induced myocardial stress in rats.
    Fitoterapia, 2001, Volume: 72, Issue:4

    Topics: Animals; Cardiotonic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Isoproterenol; Lipid P

2001
Enhanced in vivo and in vitro contractile responses to beta(2)-adrenergic receptor stimulation in dogs susceptible to lethal arrhythmias.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 91, Issue:4

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals;

2001
No loss in the in vivo efficacy of ischemic preconditioning in middle-aged and old rabbits.
    Journal of the American College of Cardiology, 2001, Nov-15, Volume: 38, Issue:6

    Topics: Aging; Analysis of Variance; Animals; Cardiotonic Agents; Hemodynamics; Ischemic Preconditioning, My

2001
Cardioprotective potential of ocimum sanctum in isoproterenol induced myocardial infarction in rats.
    Molecular and cellular biochemistry, 2001, Volume: 225, Issue:1-

    Topics: Animals; Cardiotonic Agents; Cell Membrane; Dose-Response Relationship, Drug; Female; Glutathione; H

2001
Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats.
    Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:2

    Topics: Administration, Oral; Angina Pectoris; Animals; Azocines; Coronary Disease; Electrocardiography; Iso

2002
Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity.
    Cardiovascular research, 2002, Feb-01, Volume: 53, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases;

2002
Synergistic effect of nicorandil and amlodipine on mitochondrial function during isoproterenol-induced myocardial infarction in rats.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:1

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Creatine Kinase; Drug Synergism; Isoproterenol; L-Lac

2002
99mTc-glucarate for detection of isoproterenol-induced myocardial infarction in rats.
    International journal of pharmaceutics, 2002, Feb-21, Volume: 233, Issue:1-2

    Topics: Animals; Cardiotonic Agents; Glucaric Acid; Isoproterenol; Male; Myocardial Infarction; Organotechne

2002
Effect of diabetes mellitus on hemodynamic and cardiometabolic correlates in experimental myocardial infarction.
    Advances in experimental medicine and biology, 2001, Volume: 498

    Topics: Analysis of Variance; Animals; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal;

2001
Antiarrhythmic efficacy of combined I(Ks) and beta-adrenergic receptor blockade.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:1

    Topics: Acetamides; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents;

2002
Effects of metabolic and pharmacologic interventions on myocardial infarct size following coronary occlusion.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 587

    Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Assisted Circulation

1976
The effect of beta-blockade on ST segment elevation after acute myocardial infarction in man with some experimental observations.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 587

    Topics: Acute Disease; Adrenergic beta-Antagonists; Coronary Circulation; Heart Rate; Humans; Isoproterenol;

1976
[Protective drug actions in experimental myocardial infarct].
    Folia medica Cracoviensia, 1976, Volume: 18, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Indomethacin; Isoproterenol; Male; Mechlorethamine; Myocardial

1976
[Use of dopamine in the treatment of cardiogenic shock. Preliminary results].
    Annales de l'anesthesiologie francaise, 1975, Volume: 16, Issue:9

    Topics: Aged; Diuresis; Dopamine; Female; Furosemide; Glucagon; Humans; Isoproterenol; Male; Middle Aged; My

1975
Interaction of anesthesia, beta-receptor blockade, and blood loss in dogs with induced myocardial infarction.
    Anesthesiology, 1976, Volume: 45, Issue:3

    Topics: Acetylcholine; Adrenergic beta-Antagonists; Anesthesia, General; Animals; Coronary Circulation; Dogs

1976
Arrhythmias in myocardial infarction.
    The Medical clinics of North America, 1976, Volume: 60, Issue:2

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac Complexes, Premature; D

1976
[Catecholamine in the myocardium; a fluorescence histochemical study].
    Japanese circulation journal, 1975, Volume: 39, Issue:3

    Topics: Animals; Atrioventricular Node; Cardiomegaly; Catecholamines; Dogs; Heart Atria; Heart Block; Heart

1975
Experimental myocardial infarction with left ventricular failure in the isolated perfused rat heart. Effects of isoproterenol and pacing.
    Journal of molecular and cellular cardiology, 1975, Volume: 7, Issue:2

    Topics: Animals; Blood Pressure; Cardiac Output; Cardiomegaly; Disease Models, Animal; Heart; Heart Failure;

1975
Quantitation of isoprenaline-induced changes in the ventricular myocardium.
    Cardiovascular research, 1975, Volume: 9, Issue:6

    Topics: Animals; Body Weight; Cardiomegaly; Collagen; Dose-Response Relationship, Drug; Heart; Heart Ventric

1975
Role of hypertension in ischemic heart disease and cerebral vascular disease in the cynomolgus monkey with coarctation of the aorta.
    Circulation research, 1977, Volume: 40, Issue:5 Suppl 1

    Topics: Animals; Aortic Coarctation; Blood Pressure; Cardiomegaly; Cardiovascular Diseases; Cerebral Arterie

1977
[Severe diphtheria with acute myocardial infarction (author's transl)].
    Wiener medizinische Wochenschrift (1946), 1979, May-15, Volume: 129, Issue:9

    Topics: Cardiomegaly; Child; Diphtheria; Diphtheria Antitoxin; Female; Humans; Hydrocortisone; Isoproterenol

1979
[Myocardial hypertrophy in the course of experimental infarct in the rat].
    Giornale italiano di cardiologia, 1979, Volume: 9, Issue:4

    Topics: Animals; Cardiomegaly; Isoproterenol; Myocardial Infarction; Myocardium; Radioisotopes; Rats; Thalli

1979
[Catecholamines for treatment of severe heart failure (author's transl)].
    Zeitschrift fur Kardiologie, 1979, Volume: 68, Issue:5

    Topics: Catecholamines; Coronary Circulation; Dobutamine; Dopamine; Epinephrine; Heart Failure; Humans; Isop

1979
[Treatment of coronary shock].
    Kardiologiia, 1975, Volume: 15, Issue:4

    Topics: Adrenergic beta-Antagonists; Cardiac Glycosides; Coronary Care Units; Electric Countershock; Humans;

1975
[Protective action of drugs against myocardial damage in rats].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1975, Oct-06, Volume: 30, Issue:40

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Disease Mode

1975
Prehospital brady-asystolic cardiac arrest.
    Annals of internal medicine, 1978, Volume: 88, Issue:6

    Topics: Aged; Arrhythmias, Cardiac; Atropine; Bicarbonates; Bradycardia; Electrocardiography; Epinephrine; F

1978
Effect of isoproterenol on regional myocardial perfusion and tissue oxygenation in acute myocardial infarction.
    American heart journal, 1979, Volume: 97, Issue:3

    Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Dogs; Heart; Hemodynamics; Isoproterenol; Lac

1979
Reticuloendothelial system function following isoproterenol-induced myocardial injury.
    The American journal of physiology, 1979, Volume: 236, Issue:6

    Topics: Animals; Isoproterenol; Liver; Male; Mononuclear Phagocyte System; Myocardial Infarction; Phagocytos

1979
Exercise stress testing and systolic time intervals.
    Japanese circulation journal, 1979, Volume: 43, Issue:3

    Topics: Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Heart Rate; Humans; Infusions

1979
Effect of gonadectomy on isoproterenol-induced myocardial infarction.
    Angiology, 1979, Volume: 30, Issue:6

    Topics: Adrenal Glands; Animals; Aspartate Aminotransferases; Body Weight; Creatine Kinase; Female; Heart; I

1979
Effect of CCL4-induced cirrhosis on the pathophysiologic course of acute myocardial infarction in nonarteriosclerotic vs arteriosclerotic male rats.
    Atherosclerosis, 1979, Volume: 32, Issue:3

    Topics: Alanine Transaminase; Animals; Arteriosclerosis; Aspartate Aminotransferases; Body Weight; Carbon Te

1979
Opposing effects of deoxycorticosterone and spironolactone on isoprenaline-induced myocardial infarction.
    Cardiovascular research, 1979, Volume: 13, Issue:2

    Topics: Animals; Body Weight; Corticosterone; Desoxycorticosterone; Isoproterenol; Lipids; Male; Myocardial

1979
A temporal profile of changes in myocardial manganese after isoprenaline induced cardiac necrosis in albino rats.
    Archivum immunologiae et therapiae experimentalis, 1979, Volume: 27, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Disease Models, Animal; Electrocardiography; Isoproterenol; L-

1979
Functional characterization of left ventricular segmental responses during the initial 24 h and 1 wk after experimental canine myocardial infarction.
    The Journal of clinical investigation, 1979, Volume: 64, Issue:4

    Topics: Animals; Dogs; Dopamine; Electrocardiography; Heart Ventricles; Isoproterenol; Myocardial Contractio

1979
Isoprenaline-induced myocardial infarction in spontaneously hypertensive rats.
    Cardiovascular research, 1979, Volume: 13, Issue:8

    Topics: Animals; Heart Failure; Hypertension; Isoproterenol; Liver; Male; Myocardial Infarction; Myocardium;

1979
On significance of plasma fibrinogen level to assess severity of myocardial damage--an experimental study.
    Indian journal of experimental biology, 1979, Volume: 17, Issue:6

    Topics: Animals; Cardiomyopathies; Female; Fibrinogen; Isoproterenol; Male; Myocardial Infarction; Myocardiu

1979
Myocardial infarction in spontaneously hypertensive rats with superimposed adrenal-regeneration hypertension.
    British journal of experimental pathology, 1979, Volume: 60, Issue:4

    Topics: Adrenal Glands; Animals; Blood Urea Nitrogen; Body Weight; Corticosterone; Enzymes; Female; Hyperten

1979
Prophylaxis of ventricular fibrillation after acute experimental coronary occlusion by chronic beta-adrenoceptor blockade with atenolol.
    Cardiovascular research, 1979, Volume: 13, Issue:10

    Topics: Animals; Arrhythmias, Cardiac; Atenolol; Dogs; Drug Administration Schedule; Heart Rate; Isoproteren

1979
Myocardial infarction complicated by heart block--treatment and long-term prognosis.
    Acta medica Scandinavica, 1979, Volume: 206, Issue:6

    Topics: Aged; Female; Heart Block; Humans; Isoproterenol; Male; Middle Aged; Myocardial Infarction; Pacemake

1979
[The role of the platelets in myocardial infarction induced by isoproterenol in the rat (author's transl)].
    Giornale italiano di cardiologia, 1979, Volume: 9, Issue:7

    Topics: Animals; Aspirin; Calcium; Coronary Circulation; Coronary Vessels; Isoproterenol; Myocardial Infarct

1979
[The role of calcium in the pathogenesis of experimental infarct induced with isoproterenol in the rat. Preliminary findings. I].
    Minerva cardioangiologica, 1979, Volume: 27, Issue:12

    Topics: Animals; Calcium; Isoproterenol; Male; Myocardial Infarction; Rats; Verapamil

1979
[Experimental infarcts induced with the combination of DOCA and isoproterenol in rats].
    Bollettino della Societa italiana di biologia sperimentale, 1977, May-30, Volume: 53, Issue:10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Creatine Kinase; Desoxycorticosterone; I

1977
[Experimental infarcts in rats due to 1-3-4 dihydroxyphenyl-isopropyl-aminoethanol chlorhydrate].
    Bollettino della Societa italiana di biologia sperimentale, 1977, Dec-15, Volume: 53, Issue:23

    Topics: Animals; Electrocardiography; Isoproterenol; Myocardial Infarction; Rats; Transaminases

1977
Pathogenesis of isoproterenol-induced myocardial lesions: its reation to human 'coagulative myocytolysis'.
    Cardiology, 1978, Volume: 63, Issue:3

    Topics: Animals; Autoradiography; Histocytochemistry; Humans; Isoproterenol; Microscopy, Electron; Myocardia

1978
A temporal profile of myocardial zinc changes after isoproterenol induced cardiac necrosis.
    Japanese circulation journal, 1978, Volume: 42, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Electrocardiography; Heart; Isoprotereno

1978
[Myocardial lesions caused by catecholamines (isoproterenol). Study with optical and electronic microscopy].
    Revista espanola de cardiologia, 1978, Volume: 31, Issue:1 Pt 2

    Topics: Animals; Humans; Isoproterenol; Microscopy, Electron; Mitochondria, Heart; Myocardial Infarction; Ne

1978
Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats.
    Atherosclerosis, 1978, Volume: 29, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Clof

1978
Subcutaneous isoproterenol: a convenient rat model for early detection of myocardial necrosis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1978, Volume: 19, Issue:8

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Radiation; Isoproterenol; Myocardial In

1978
Experimental catecholamine-induced acute myocardial necrosis.
    Advances in cardiology, 1978, Volume: 25

    Topics: Acute Disease; Animals; Catecholamines; Dogs; Heart; Hemodynamics; Infusions, Parenteral; Isoprotere

1978
Effects of pharmacological intervention on infarct size following induced myocardial infarction in rats.
    Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:11

    Topics: Animals; Creatine Kinase; Hyaluronoglucosaminidase; Insulin; Isoproterenol; Male; Myocardial Infarct

1978
[Prevention of the myocardial damaging effect of isadrin by curantil].
    Biulleten' eksperimental'noi biologii i meditsiny, 1978, Volume: 86, Issue:11

    Topics: Animals; Coronary Disease; Dipyridamole; Electrocardiography; Female; Isoproterenol; Male; Myocardia

1978
Repeated myocardial infarction in non-arteriosclerotic and arteriosclerotic Sprague-Dawley rats.
    British journal of experimental pathology, 1978, Volume: 59, Issue:6

    Topics: Animals; Arteriosclerosis; Blood Glucose; Blood Urea Nitrogen; Body Weight; Corticosterone; Isoprote

1978
Age-dependent variations in the intensity of isoprenaline-induced myocardial lesions in rats.
    Cor et vasa, 1978, Volume: 20, Issue:6

    Topics: Age Factors; Animals; Isoproterenol; Myocardial Infarction; Oxytetracycline; Rats; Technetium

1978
Effect of verapamil on the transmural energy metabolism in the isoproterenol-induced myocardial lesion.
    Japanese heart journal, 1978, Volume: 19, Issue:6

    Topics: Adenosine Triphosphate; Animals; Calcium; Energy Metabolism; Heart; Isoproterenol; Lactates; Male; M

1978
Immunofluorescent and migration inhibition studies in rats with experimental myocardial infarction.
    Acta physiologica Academiae Scientiarum Hungaricae, 1976, Volume: 47, Issue:1

    Topics: Animals; Antibodies; Antibody Specificity; Cell Migration Inhibition; Fluorescent Antibody Technique

1976
Measurement of stroke volume from pulmonary artery pressure record in man.
    British heart journal, 1975, Volume: 37, Issue:1

    Topics: Blood Pressure; Cardiac Catheterization; Cardiac Output; Cardiomyopathy, Hypertrophic; Catecholamine

1975
Effect of zinc on acute and chronic isoproterenol induced heart injury.
    Journal of molecular and cellular cardiology, 1977, Volume: 9, Issue:2

    Topics: Adrenal Glands; Animals; Calcium; Collagen; Heart; Isoproterenol; Male; Myocardial Infarction; Myoca

1977
Contrasting effects of dopamine and isoproterenol in experimental myocardial infarction.
    The American journal of cardiology, 1977, Volume: 39, Issue:3

    Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Dopamine; Electrocardiography; Heart Rate; Isop

1977
Evaluation of precordial orthogonal vectorcardiographic lead ST-segment magnitude in the assessment of myocardial ischemic injury.
    Circulation, 1977, Volume: 55, Issue:5

    Topics: Animals; Dogs; Evaluation Studies as Topic; Heart Conduction System; Isoproterenol; Methoxamine; Myo

1977
The effect of dobutamine on cardiac oxygen balance, regional blood flow, and infarction severity after coronary artery narrowing in dogs.
    Circulation research, 1977, Volume: 41, Issue:3

    Topics: Animals; Catecholamines; Coronary Circulation; Coronary Vessels; Dobutamine; Dogs; Heart; Heart Rate

1977
Effects of exercise on the severity of isoproterenol-induced myocardial infarction.
    Medicine and science in sports, 1977,Summer, Volume: 9, Issue:2

    Topics: Animals; Body Weight; Creatine Kinase; Exercise Test; Isoproterenol; Male; Myocardial Infarction; My

1977
Combined effects of acute cerebrovascular ischemia and myocardial infarction in arteriosclerotic, male Sprague-Dawley rats.
    Angiology, 1977, Volume: 28, Issue:9

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Arteriosclerosis; Blood Glucose; Blood Urea Nitrog

1977
Localization by autoradiography of tritiated isoproterenol in "infarct-like" lesions of rat myocardium.
    American heart journal, 1976, Volume: 92, Issue:3

    Topics: Animals; Autoradiography; Disease Models, Animal; Isoproterenol; Myocardial Infarction; Myocardium;

1976
Haemodynamics and treatment of right ventricular infarction.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1976, Jul-10, Volume: 50, Issue:29

    Topics: Aged; Blood Pressure; Dextrans; Female; Heart Ventricles; Hemodynamics; Humans; Isoproterenol; Male;

1976
Proceedings: Effects of tachycardia and isoprenaline on coronary blood flow: observations on pathogenesis of myocardial infarction.
    British heart journal, 1976, Volume: 38, Issue:8

    Topics: Animals; Coronary Circulation; Dogs; Heart Rate; Isoproterenol; Myocardial Infarction; Stimulation,

1976
[Comparative effects of norepinephrine, isoproterenol and dopamine on myocardial function and metabolism during experimental myocardial infarction (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1976, Volume: 65, Issue:1

    Topics: Animals; Coronary Circulation; Dogs; Dopamine; Drug Evaluation; Heart; Isoproterenol; Myocardial Inf

1976
Coronary steal: its role in detrimental effect of isoproterenol after acute coronary occlusion in dogs.
    The American journal of cardiology, 1976, Volume: 38, Issue:7

    Topics: Adenosine; Animals; Blood Pressure; Collateral Circulation; Coronary Circulation; Disease Models, An

1976
[Modification of the isoprenaline-induced myocardial necrosis using trapidil].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1976, Sep-15, Volume: 31, Issue:18

    Topics: Animals; Cardiomyopathies; Disease Models, Animal; Isoproterenol; Male; Myocardial Infarction; Necro

1976
Isoprenaline-induced changes in regional myocardial perfusion in the pathogenesis of myocardial necrosis.
    British journal of experimental pathology, 1976, Volume: 57, Issue:6

    Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Isoproterenol; Male; Myocardial Inf

1976
Comparative effects of cortisone, dianabol and enovid on isoprenaline-induced myocardial infarction in arteriosclerotic vs nonarteriosclerotic rats.
    British journal of experimental pathology, 1976, Volume: 57, Issue:6

    Topics: Adrenal Glands; Animals; Arteriosclerosis; Body Weight; Cortisone; Dose-Response Relationship, Drug;

1976
Effect of biotin on biochemical changes following isoproterenol-induced myocardial infarction in rats.
    Chemical & pharmaceutical bulletin, 1976, Volume: 24, Issue:6

    Topics: Animals; Biotin; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats

1976
[Quantitative analysis of isoproterenol induced rat heart necrosis by point counting method].
    Verhandlungen der Anatomischen Gesellschaft, 1976, Issue:70 Pt 2

    Topics: Animals; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats

1976
The role of myocardial membrane lipids in the development of cardiac necrosis.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 587

    Topics: Adenosine Triphosphate; Age Factors; Animals; Arachidonic Acids; Dietary Fats; Energy Metabolism; Fa

1976
Effects of lipolytic and inotropic stimulation on myocardial ischemic injury.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 587

    Topics: Animals; Cardiac Output; Catecholamines; Coronary Disease; Dogs; Fatty Acids, Nonesterified; Humans;

1976
Prenylamine inhibition of isoproterenol induced myocardial lesions. Histochemical and ultrastructural findings.
    Acta cardiologica, 1976, Volume: 31, Issue:5

    Topics: Animals; Calcium; Disease Models, Animal; Isoproterenol; Myocardial Infarction; Myocardium; Oxygen C

1976
Proceedings: Quantification of isoproterenol-induced myocardial necroses and the protective effect of calcium-antagonistic compounds by point counting.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 287 Suppl

    Topics: Animals; Calcium; Histological Techniques; Isoproterenol; Methods; Myocardial Infarction

1975
Pathophysiology of subendocardial ischaemia.
    British medical journal, 1975, Jan-11, Volume: 1, Issue:5949

    Topics: Anemia; Animals; Aortic Valve Insufficiency; Aortic Valve Stenosis; Arteriosclerosis; Blood Flow Vel

1975
[Key-role of intracellular calcium overload in acute necrosis of the myocardium. Cardioprotection with verapamil].
    Minerva medica, 1975, May-23, Volume: 66, Issue:38

    Topics: Adenosine Triphosphate; Animals; Calcium; Catecholamines; Dihydrotachysterol; Fludrocortisone; Heart

1975
Metabolic response after isoproterenol-induced myocardial infarction in arteriosclerotic breeder vs nonarteriosclerotic virgin intact and gonadectomized male rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 148, Issue:4

    Topics: Animals; Arteriosclerosis; Blood Glucose; Castration; Fatty Acids, Nonesterified; Insulin; Isoproter

1975
Evaluation of precordial electrocardiographic mapping as a means of assessing changes in myocardial ischemic injury.
    Circulation, 1975, Volume: 52, Issue:1

    Topics: Acute Disease; Animals; Creatine Kinase; Disease Models, Animal; Dogs; Electrocardiography; Evaluati

1975
Cardiogenic shock and its current treatment.
    Texas medicine, 1975, Volume: 71, Issue:4

    Topics: Acute Disease; Adult; Aged; Assisted Circulation; Digitalis Glycosides; Dopamine; Female; Glucagon;

1975
Proceedings: Influence on the running performance of isoprenaline damaged rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 287 Suppl

    Topics: Animals; Aspartic Acid; Isoproterenol; Magnesium; Male; Myocardial Infarction; Physical Exertion; Po

1975
An electrocardiographic pattern of acute myocardial infarction associated with excessive use of aerosolized isoproterenol.
    Chest, 1975, Volume: 68, Issue:1

    Topics: Acute Disease; Adult; Aerosols; Animals; Asthma; Electrocardiography; Female; Hemodynamics; Humans;

1975
Letter: Aerosolized isoproterenol and myocardial infarction analog.
    Chest, 1975, Volume: 68, Issue:2

    Topics: Aerosols; Humans; Isoproterenol; Myocardial Infarction

1975
Effects of hormonal pretreatment of cardiac necrosis in the Japanese quail.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 149, Issue:2

    Topics: Animals; Castration; Coturnix; Estradiol; Female; Hematocrit; Isoproterenol; Male; Myocardial Infarc

1975
Prolyl hydroxylase and collagen metabolism after experimental mycardial infarction.
    The American journal of physiology, 1975, Volume: 228, Issue:1

    Topics: Animals; Collagen; Hydroxyproline; Isoproterenol; Male; Mixed Function Oxygenases; Myocardial Infarc

1975
Morphological changes after simultaneous administration of isoproterenol (ISO) and K+,MG2+-Aspartate (KMg-ASP) as a physiological Ca2+ antagonist.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:6

    Topics: Animals; Aspartic Acid; Calcium; Dogs; Extracellular Space; Glycogen; Histocytochemistry; Isoprotere

1975
[Influencing myocardial necroses induced by isoproterenol, the physiologic antagonist of calcium, in experiments (author's transl)].
    Bratislavske lekarske listy, 1975, Volume: 64, Issue:4

    Topics: Animals; Aspartic Acid; Calcium; Dogs; Isoproterenol; Male; Myocardial Infarction; Myocardium; Necro

1975
Electrophysiologic and pharmacologic studies in a patient with acute myocardial infarction complicated by intraventricular and atrioventricular block.
    European journal of cardiology, 1975, Volume: 3, Issue:4

    Topics: Amiodarone; Bundle-Branch Block; Electrocardiography; Electrophysiology; Heart Block; Heart Conducti

1975
Metabolic and histopathologic changes in arteriosclerotic versus nonarteriosclerotic rats following isoproterenol-induced myocardial infarction with superimposed diabetes.
    Metabolism: clinical and experimental, 1975, Volume: 24, Issue:12

    Topics: Acute Disease; Animals; Arteriosclerosis; Diabetes Mellitus, Experimental; Disease Models, Animal; F

1975
Myocardial metabolism at different environmental temperatures in experimental myocardial necrosis.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Adrenal Glands; Alanine Transaminase; Animals; Ascorbic Acid; Aspartate Aminotransferases; Cardiomyo

1975
Membrane phospholipid metabolism in the isoproterenol-induced cardiomyopathy of the rat.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Animals; Cardiolipins; Cardiomyopathies; Cell Membrane; Cytidine Monophosphate; Isoproterenol; Liver

1975
Role of free fatty acids in catecholamine-induced cardiac necrosis.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 6

    Topics: Animals; Blood Pressure; Creatine Kinase; Fatty Acids, Nonesterified; Female; Heart Rate; Isoprotere

1975
The effects of isoprenaline on epicardial ST-segment elevation, lactate production, and myocardial blood flow following coronary artery ligation.
    Cardiovascular research, 1975, Volume: 9, Issue:6

    Topics: Acute Disease; Animals; Blood Pressure; Coronary Circulation; Dogs; Electrocardiography; Female; Hea

1975
Serum prolactin levels in rats following isoproterenol-induced myocardial infarction.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 150, Issue:3

    Topics: Androgens; Animals; Arteriosclerosis; Female; Isoproterenol; Male; Myocardial Infarction; Prolactin;

1975
Time-dependent changes of collateral coronary reactivity in the dog.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 10

    Topics: Animals; Catecholamines; Collateral Circulation; Coronary Circulation; Dogs; Female; Hypoxia; Isopro

1975
Effect of conditioning on myocardial metabolism after myocardial infarction.
    Recent advances in studies on cardiac structure and metabolism, 1975, Volume: 10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Creatine Kinase; Fatty Acids, Nonesterif

1975
Electrolytes in myocardial infarction.
    Comprehensive therapy, 1975, Volume: 1, Issue:7

    Topics: Animals; Calcium; Cell Membrane Permeability; Disease Models, Animal; Humans; Isoproterenol; Magnesi

1975
[Treatment of arrhythmia in general practice].
    Wiener medizinische Wochenschrift (1946), 1975, Nov-14, Volume: 125, Issue:46

    Topics: Ajmaline; Anti-Arrhythmia Agents; Aprindine; Arrhythmia, Sinus; Arrhythmias, Cardiac; Bradycardia; H

1975
[Pharmacology of cornary dilator agent, trapymin. (2) Analysis of its mode of action].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:7

    Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Glucose; Calcium Chloride; Catecholamin

1975
Inotropic agents and infarct size. Theoretical and practical considerations.
    The American journal of cardiology, 1976, Mar-31, Volume: 37, Issue:4

    Topics: Acute Disease; Animals; Cardiac Volume; Digitalis Glycosides; Heart; Heart Rate; Humans; Isoproteren

1976
Autonomic manipulation influences both temporal and frequency analyses of late potentials.
    Pacing and clinical electrophysiology : PACE, 1992, Volume: 15, Issue:11 Pt 2

    Topics: Adrenergic beta-Antagonists; Atropine; Electrocardiography; Female; Heart Conduction System; Humans;

1992
Captopril enhances intracellular calcium handling and beta-adrenergic responsiveness of myocardium from rats with postinfarction failure.
    Circulation research, 1992, Volume: 71, Issue:4

    Topics: Animals; Calcium; Captopril; Heart; Heart Failure; Hemodynamics; Isoproterenol; Male; Myocardial Con

1992
Captopril modifies the response of infarcted rat hearts to isoprenaline stimulation.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:5

    Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril;

1992
Triggered activity as arrhythmogenic mechanism after myocardial infarction: clinical and electrophysiologic study of one case.
    Clinical cardiology, 1992, Volume: 15, Issue:9

    Topics: Aged; Cardiac Pacing, Artificial; Electric Stimulation; Electrocardiography; Exercise Test; Female;

1992
Effect of aspirin on isoproterenol induced myocardial infarction--a pilot study.
    Indian journal of biochemistry & biophysics, 1992, Volume: 29, Issue:4

    Topics: Administration, Oral; Animals; Aspirin; Creatine Kinase; Isoproterenol; L-Lactate Dehydrogenase; Lip

1992
[Studies on early stage changes of peroxide lipid in isoproterenol-induced myocardial injury].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1992, Volume: 112, Issue:8

    Topics: Animals; Blood Chemical Analysis; Isoproterenol; Lipid Peroxides; Male; Myocardial Infarction; Rats;

1992
[The capacity for reactive DNA synthesis of the myocytes in the heart conduction system in experimental and clinical myocardial pathology].
    Tsitologiia, 1992, Volume: 34, Issue:5

    Topics: Adult; Aged; Animals; Autoradiography; Cardiomegaly; Cell Nucleus; Cytophotometry; DNA; Female; Hear

1992
Cardioprotective effect of cromakalim (potassium channel opener) in isoproterenol induced myocardial infarction in rats.
    Indian journal of experimental biology, 1992, Volume: 30, Issue:7

    Topics: Animals; Aspartate Aminotransferases; Benzopyrans; Blood Coagulation; Cromakalim; Female; Glycogen;

1992
Effect of aspirin on serum lipoprotein profile in rats subjected to myocardial stress by isoproterenol.
    Indian journal of experimental biology, 1992, Volume: 30, Issue:6

    Topics: Animals; Aspirin; Isoproterenol; Lipoproteins; Male; Myocardial Infarction; Rats; Rats, Inbred Strai

1992
Failure to reduce experimental myocardial infarct size with ibuprofen pre-treatment in rats.
    Indian journal of physiology and pharmacology, 1992, Volume: 36, Issue:2

    Topics: Animals; Female; Heart; Ibuprofen; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats

1992
Autonomic mechanisms in heart rate variability after isoproterenol-induced myocardial damage in rats.
    Journal of the autonomic nervous system, 1992, Volume: 38, Issue:1

    Topics: Animals; Autonomic Nervous System; Cardiomyopathies; Electrocardiography; Fourier Analysis; Heart Ra

1992
Effects of amiodarone on cardiac electrophysiology and inducibility of arrhythmias in chronically infarcted dogs: late arrhythmias, haemodynamics, and sympatholytic actions.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:6

    Topics: Action Potentials; Amiodarone; Animals; Arrhythmias, Cardiac; Chronic Disease; Dogs; Electrocardiogr

1990
Cardiovascular responses to the stereoisomers of dobutamine in isolated rat hearts 48 hours after acute myocardial infarction.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Dobutamine; Dose-Response Relationship

1991
Reduction of experimental myocardial infarct size by pre-treatment with magnesium sulfate in rats.
    Indian journal of physiology and pharmacology, 1991, Volume: 35, Issue:1

    Topics: Animals; Catecholamines; Coronary Vessels; Eosine Yellowish-(YS); Female; Hematoxylin; Isoproterenol

1991
Hypothyroidism renders protection against lethal ventricular arrhythmias in a conscious canine model of sudden death.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dogs; Electroencephalography; Electrophysiolo

1991
Evaluation of cellular viability by quantitative autoradiographic study of myocardial uptake of a fatty acid analogue in isoproterenol-induced focal rat heart necrosis.
    European journal of nuclear medicine, 1991, Volume: 18, Issue:11

    Topics: Animals; Autoradiography; Carbon Radioisotopes; Cell Survival; Fatty Acids; Heart; Iodobenzenes; Iso

1991
In vivo labeling studies on the biosynthesis and degradation of collagen in experimental myocardial infarction.
    Biochemistry international, 1991, Volume: 24, Issue:3

    Topics: Animals; Collagen; Female; Hydroxyproline; Isoproterenol; Myocardial Infarction; Proline; Radioactiv

1991
Converting enzyme inhibition after experimental myocardial infarction in rats: comparative study between spirapril and zofenopril.
    Cardiovascular research, 1991, Volume: 25, Issue:11

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Enalapril; Hea

1991
Effect of ethanol administration on metabolism of lipids in heart and aorta in isoproterenol induced myocardial infarction in rats.
    Indian journal of experimental biology, 1991, Volume: 29, Issue:3

    Topics: Animals; Aorta; Ethanol; Isoproterenol; Lipid Metabolism; Male; Myocardial Infarction; Myocardium; R

1991
Effect of coconut oil & safflower oil on lipids in isoproterenol induced myocardial infarction in rats.
    The Indian journal of medical research, 1991, Volume: 94

    Topics: Animals; Aorta; Coconut Oil; Cocos; Dietary Fats; Isoproterenol; Lipids; Male; Myocardial Infarction

1991
[Variations in arrhythmogenic response to catecholamines in acute myocardial ischemia].
    Cardiologia (Rome, Italy), 1991, Volume: 36, Issue:3

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Catecholamines; Dogs; Heart; In Vitro Techniques;

1991
Influence of isoproterenol-induced myocardial infarction on certain glycohydrolases and cathepsins in rats.
    Biochemical medicine and metabolic biology, 1991, Volume: 45, Issue:1

    Topics: Animals; Biomarkers; Cathepsins; Female; Glycoside Hydrolases; Isoproterenol; Lysosomes; Myocardial

1991
Alterations in the heart lysosomal stability in isoproterenol induced myocardial infarction in rats.
    Biochemistry international, 1990, Volume: 22, Issue:2

    Topics: Animals; Glucuronidase; Isoproterenol; Lysosomes; Myocardial Infarction; Myocardium; Rats

1990
Changes in performance of the surviving myocardium after left ventricular infarction in rats.
    Cardiovascular research, 1990, Volume: 24, Issue:9

    Topics: Animals; Blood Pressure; Calcium; Cardiomegaly; Disease Models, Animal; Female; Heart; Isoproterenol

1990
Beta-adrenergic-mediated influences on microscopic conduction in epicardial regions overlying infarcted myocardium.
    Circulation research, 1990, Volume: 67, Issue:2

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Dogs; Electric Conductivity; Electric Stimulation;

1990
Effect of isoproterenol on induction of ventricular tachyarrhythmias in the normal and infarcted canine heart.
    International journal of cardiology, 1990, Volume: 29, Issue:2

    Topics: Animals; Dogs; Electrocardiography; Heart Rate; Isoproterenol; Myocardial Infarction; Tachycardia; V

1990
Protective action of aspirin in experimental myocardial infarction induced by isoproterenol in rats and its effect on lipid peroxidation.
    Indian journal of experimental biology, 1990, Volume: 28, Issue:5

    Topics: Animals; Aspirin; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction; Rats; Rats, Inbred

1990
Alternating Wenckebach periods in acute inferior myocardial infarction: clinical, electrocardiographic, and therapeutic characterization.
    Pacing and clinical electrophysiology : PACE, 1986, Volume: 9, Issue:4

    Topics: Adult; Aged; Atropine; Blood Pressure; Bradycardia; Electrocardiography; Female; Heart Block; Humans

1986
Early myocardial infarction. A feasible histologic diagnostic procedure.
    Japanese heart journal, 1986, Volume: 27, Issue:3

    Topics: Animals; Isoproterenol; Myocardial Infarction; Myocardium; Rats; Staining and Labeling; Time Factors

1986
[The efficacy of quinazopyrine, preparation E and riboxin in experimental myocardial infarct].
    Vrachebnoe delo, 1989, Issue:12

    Topics: Animals; Cardiovascular Agents; Drug Evaluation, Preclinical; Heart; Inosine Diphosphate; Inosine Nu

1989
Changes in plasma level of alpha-atrial natriuretic polypeptide (alpha-ANP) and responsiveness of the aorta to exogenous alpha-ANP subsequent to myocardial infarction in rats.
    Japanese journal of pharmacology, 1989, Volume: 49, Issue:4

    Topics: Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Body Weight; Heart; In Vitro Techniques; Isopro

1989
Elevated blood pressure and heart rate in rats exposed to a coal-derived complex organic mixture.
    Journal of applied toxicology : JAT, 1989, Volume: 9, Issue:1

    Topics: Administration, Inhalation; Animals; Blood Pressure; Coal Tar; Diphosphates; Disease Models, Animal;

1989
Density of beta adrenoceptors in rat heart and lymphocytes 48 hours and 7 days after acute myocardial infarction.
    Cardiovascular research, 1989, Volume: 23, Issue:10

    Topics: Animals; Cell Membrane; Dobutamine; Heart; Heart Ventricles; Isoproterenol; Lymphocytes; Male; Myoca

1989
Autonomic response to coronary occlusion in animals susceptible to ventricular fibrillation.
    The American journal of physiology, 1989, Volume: 257, Issue:6 Pt 2

    Topics: Animals; Autonomic Nervous System; Blood Pressure; Coronary Disease; Coronary Vessels; Death, Sudden

1989
Effect of vitamin E on the severity of myocardial infarction induced by isoproterenol.
    The Indian journal of medical research, 1989, Volume: 90

    Topics: Animals; Enzymes; Isoproterenol; Lipids; Male; Myocardial Infarction; Rats; Rats, Inbred Strains; Vi

1989
Effect of aspartate and glutamate on experimental myocardial infarction in rats.
    Indian journal of experimental biology, 1989, Volume: 27, Issue:7

    Topics: Animals; Aspartic Acid; Female; Glutamates; Isoproterenol; Male; Myocardial Infarction; Rats

1989
Reversal of changes of lipid peroxide, xanthine oxidase and superoxide dismutase by cardio-protective drugs in isoproterenol induced myocardial necrosis in rats.
    Indian journal of experimental biology, 1989, Volume: 27, Issue:7

    Topics: Animals; Cardiovascular Agents; Isoproterenol; Lipid Peroxides; Male; Myocardial Infarction; Oxidore

1989
A morphometrical method to estimate isoproterenol-induced infarct size in the rat.
    Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:5

    Topics: Animals; Female; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Nitroblue Tetrazolium;

1989
Functional integrity of sympathetic efferent postganglionic axons in a region of stunned myocardium.
    The Canadian journal of cardiology, 1989, Volume: 5, Issue:7

    Topics: Animals; Autonomic Fibers, Postganglionic; Axons; Dogs; Efferent Pathways; Electric Stimulation; Fem

1989
Effects of chronic myocardial infarction on responsiveness to isoprenaline and the state of myocardial beta adrenoceptors in rats.
    Cardiovascular research, 1987, Volume: 21, Issue:9

    Topics: Animals; Chronic Disease; Hemodynamics; In Vitro Techniques; Isoproterenol; Male; Myocardial Contrac

1987
Effect of a synthetic short-chain ACTH 1-17 (HOE 433) on isoproterenol-induced myocardial infarction in rats.
    Indian journal of experimental biology, 1988, Volume: 26, Issue:9

    Topics: Adrenocorticotropic Hormone; Animals; Aspartate Aminotransferases; Female; Isoproterenol; L-Lactate

1988
Hypokalemia from beta 2-receptor stimulation by circulating epinephrine.
    The American journal of cardiology, 1985, Aug-30, Volume: 56, Issue:6

    Topics: Adrenergic beta-Antagonists; Digoxin; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Hum

1985
Isoprenaline-induced myocardial damage & the cardioprotective action of some beta-adrenoceptor blockers in albino rats.
    The Indian journal of medical research, 1987, Volume: 85

    Topics: Adrenergic beta-Antagonists; Animals; Female; Heart; Isoproterenol; Male; Myocardial Infarction; Myo

1987
Correlation of type A behaviour with adrenergic receptor density: implications for coronary artery disease pathogenesis.
    Lancet (London, England), 1987, Oct-24, Volume: 2, Issue:8565

    Topics: Adult; Aged; Arteriosclerosis; Blood Platelets; Coronary Disease; Cyclic AMP; Female; Humans; Interv

1987
Islet cell damage and cardiac enzyme and isoenzyme changes in isoproterenol treated rats.
    Indian journal of experimental biology, 1985, Volume: 23, Issue:6

    Topics: Animals; Female; Heart; Hexokinase; Insulin; Islets of Langerhans; Isoenzymes; Isoproterenol; L-Lact

1985
The assessment of contractile reserve after thrombolytic therapy for acute myocardial infarction.
    American heart journal, 1986, Volume: 111, Issue:5

    Topics: Adult; Blood Pressure; Female; Heart; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Myocardi

1986
Beneficial effects of defibrotide against myocardial ischemia and decline of beta-adrenoceptor function in the rabbit.
    Haemostasis, 1986, Volume: 16 Suppl 1

    Topics: Animals; Creatine Kinase; Fibrinolytic Agents; Histamine; In Vitro Techniques; Isoproterenol; Ligati

1986
Beta-adrenergic receptor properties of canine myocardium: effects of chronic myocardial infarction.
    Journal of the American College of Cardiology, 1986, Volume: 8, Issue:2

    Topics: Adenylyl Cyclases; Animals; Coronary Circulation; Dogs; Endocardium; Fluorides; Isoproterenol; Myoca

1986
[Effect of polypeptides isolated from the heart on the course of experimental myocardial infarct].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:1

    Topics: Animals; Cattle; Cytochrome c Group; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female

1987
Alterations in isoproterenol-induced cardiac metabolic changes by a quaternary analog of propranolol, UM-272.
    Acta cardiologica, 1985, Volume: 40, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Creatine Kinase; Dose-Response Relationship, Drug; Energy Metabolis

1985
Alprazolam decreases isoproterenol induced myocardial damage in the rat.
    Cardiovascular research, 1988, Volume: 22, Issue:6

    Topics: Alprazolam; Animals; Electrocardiography; Heart; Heart Rate; Isoproterenol; Male; Myocardial Infarct

1988
Effect of adenosine and inosine on experimental myocardial infarction in rats.
    Indian journal of experimental biology, 1988, Volume: 26, Issue:10

    Topics: Adenosine; Animals; Female; Inosine; Isoproterenol; Male; Myocardial Infarction; Myocardium; Rats

1988
Cardioprotective effect of prostacyclin and 7-oxo-PGI2 in rats against chronic isoproterenol damage.
    Prostaglandins, 1987, Volume: 33, Issue:4

    Topics: Animals; Epoprostenol; Heart; Isoproterenol; Male; Myocardial Infarction; Myocardium; Necrosis; Rats

1987
Effects of alloxan-induced diabetes on ischemia-reperfusion injury in rabbit hearts.
    Circulation research, 1988, Volume: 62, Issue:5

    Topics: Animals; Coronary Disease; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Heart;

1988
Changes in levels of lipid peroxides and activities of superoxide dismutase and catalase in isoproterenol induced myocardial infarction in rats.
    Indian journal of experimental biology, 1987, Volume: 25, Issue:6

    Topics: Animals; Catalase; Isoproterenol; Lipid Peroxides; Male; Myocardial Infarction; Rats; Rats, Inbred S

1987
A method of analyzing regional myocardial function: mean wall stress-area strain relationship.
    Japanese circulation journal, 1987, Volume: 51, Issue:1

    Topics: Animals; Cardiac Catheterization; Coronary Disease; Dogs; Heart Septum; Humans; Isoproterenol; Myoca

1987
Studies on the calcium antagonistic action of tetrandrine: XIII. Protective effect of tetrandrine on myocardial hypoxia and necrosis induced by isoproterenol in rats.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1986, Volume: 6, Issue:1

    Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium Channel Blockers; Coronary Disease; Electrocardiogr

1986
The co-operative action of hyaluronidase and urokinase on the isoproterenol-induced myocardial infarction in rats.
    Thrombosis research, 1986, Apr-15, Volume: 42, Issue:2

    Topics: Animals; Drug Administration Schedule; Drug Therapy, Combination; Hyaluronoglucosaminidase; Injectio

1986
ST-segment, T-wave, and U-wave changes during myocardial ischemia and after myocardial infarction.
    The Canadian journal of cardiology, 1986, Volume: Suppl A

    Topics: Acute Disease; Adult; Aged; Coronary Circulation; Coronary Disease; Electrocardiography; Exercise Te

1986
The effect of acute hypercholesterolemia on myocardial infarct size and the no-reflow phenomenon during coronary occlusion-reperfusion.
    Circulation, 1987, Volume: 75, Issue:1

    Topics: Acute Disease; Animals; Cholesterol, Dietary; Coronary Circulation; Coronary Disease; Female; Hyperc

1987
Autonomic control of ventricular tachycardia: direct effects of beta-adrenergic blockade in 24 hour old canine myocardial infarction.
    Journal of the American College of Cardiology, 1987, Volume: 9, Issue:2

    Topics: Animals; Coronary Vessels; Dogs; Female; Heart Conduction System; Hemodynamics; Injections, Intra-Ar

1987
Effect of administration of vitamin A, ascorbic acid and nicotinamide adenine dinucleotide + flavin adenine dinucleotide on severity of myocardial infarction induced by isoproterenol in rats.
    Indian journal of experimental biology, 1985, Volume: 23, Issue:9

    Topics: Animals; Ascorbic Acid; Flavin-Adenine Dinucleotide; Isoproterenol; Male; Myocardial Infarction; NAD

1985
Effect of administration of carnitine on the severity of myocardial infarction induced by isoproterenol in rats.
    The Australian journal of experimental biology and medical science, 1986, Volume: 64 ( Pt 1)

    Topics: Animals; Aspartate Aminotransferases; Carnitine; Cholesterol; Creatine Kinase; Fatty Acids; Female;

1986
Comparison in the same patient of two programmed ventricular stimulation protocols to induce ventricular tachycardia.
    The American journal of cardiology, 1985, Feb-01, Volume: 55, Issue:4

    Topics: Cardiac Pacing, Artificial; Electric Stimulation; Humans; Isoproterenol; Myocardial Infarction; Pros

1985
Effect of age and myocardial infarction on serum and heart lactic dehydrogenase.
    Experimental gerontology, 1985, Volume: 20, Issue:1

    Topics: Age Factors; Animals; Heart; Isoproterenol; L-Lactate Dehydrogenase; Myocardial Infarction; Myocardi

1985
Effect of verapamil, nifedipine and diltiazem on experimental myocardial infarction in rats.
    Indian journal of experimental biology, 1985, Volume: 23, Issue:1

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Female; Isoproterenol; Male; Myocardial Infarction; Ni

1985
Prolonged protective effects following propranolol withdrawal against isoproterenol-induced myocardial infarction in normotensive and hypertensive rats.
    British journal of experimental pathology, 1985, Volume: 66, Issue:2

    Topics: Animals; Blood Pressure; Corticosterone; Creatine Kinase; Female; Humans; Isoproterenol; L-Lactate D

1985
[The effects of TA-064, dopamine and isoproterenol on the acutely ischemic myocardium].
    Kokyu to junkan. Respiration & circulation, 1985, Volume: 33, Issue:7

    Topics: Animals; Cardiotonic Agents; Dogs; Dopamine; Drug Evaluation; Ethanolamines; Isoproterenol; Myocardi

1985
[Intravenous isoproterenol administration for diagnosing ischemic heart disease in women: a comparison with the data from bicycle ergometry and selective coronary angiography].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:9

    Topics: Adult; Cardiomyopathy, Hypertrophic; Coronary Angiography; Coronary Disease; Exercise Test; Female;

1985
Acute myocardial histopathology in normal and arteriosclerotic rats during isoproterenol-induced infarction.
    British journal of experimental pathology, 1970, Volume: 51, Issue:6

    Topics: Acidosis; Animals; Arteriosclerosis; Female; Hypoxia; Isoproterenol; Male; Myocardial Infarction; My

1970
Clinical cardiovascular pharmacology of dobutamine. A selective inotropic catecholamine.
    Lancet (London, England), 1974, Aug-17, Volume: 2, Issue:7877

    Topics: Aortic Valve; Blood Pressure; Cardiac Output; Catecholamines; Coronary Disease; Female; Heart; Heart

1974
Hemodynamic effects of adrenergic stimulating and blocking agents in cardiogenic shock and low output state after myocardial infarction.
    The American journal of cardiology, 1973, Volume: 31, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Animals; Blood Pr

1973
[The production of tachycardiac arrhythmia through extrasystoles. Mechanism and therapy].
    Deutsche medizinische Wochenschrift (1946), 1967, Nov-17, Volume: 92, Issue:46

    Topics: Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrocardiography; Humans; Isoproterenol; Li

1967
Catecholamines and the heart.
    Lancet (London, England), 1969, Jun-14, Volume: 1, Issue:7607

    Topics: Animals; Arrhythmias, Cardiac; Catecholamines; Dogs; Heart; Humans; Isoproterenol; Myocardial Infarc

1969
[Ventricular tachycardia with variable focus and dyskaliemia].
    Archives des maladies du coeur et des vaisseaux, 1969, Volume: 62, Issue:11

    Topics: Aged; Alcoholism; Bradycardia; Cardiac Complexes, Premature; Electrocardiography; Female; Heart Bloc

1969
Myocardial necrosis induced by isoproterenol in rats. Changes in serum protein, lipoprotein, lipids and glucose during active necrosis and repair in arteriosclerotic and nonarteriosclerotic animals.
    Angiology, 1968, Volume: 19, Issue:11

    Topics: Alpha-Globulins; Animals; Arteriosclerosis; Beta-Globulins; Blood Glucose; Blood Proteins; Fatty Liv

1968
[Role of ischemia in left ventricular function disorders in the initial stage of myocardial infarct].
    Archives des maladies du coeur et des vaisseaux, 1973, Volume: 66, Issue:4

    Topics: Aged; Cardiac Catheterization; Cardiac Output; Digitalis Glycosides; Echocardiography; Female; Heart

1973
Regional myocardial function during acute coronary artery occlusion and its modification by pharmacologic agents in the dog.
    Circulation research, 1974, Volume: 35, Issue:6

    Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Heart; Heart Rate; Hemodynamics; Isoproterenol; Myo

1974
Long-term conservative therapy of chronic AV block.
    Acta medica Scandinavica, 1974, Volume: 196, Issue:5

    Topics: Aged; Autopsy; Bundle-Branch Block; Chronic Disease; Digitalis; Diuretics; Female; Follow-Up Studies

1974
[A chronic model of necrotic cardiopathy induced by repeated administration of isadrin to experimental animals].
    Arkhiv patologii, 1967, Volume: 29, Issue:1

    Topics: Animals; Cardiomegaly; Isoproterenol; Models, Biological; Myocardial Infarction; Myocardium; Rabbits

1967
Behaviour of 86Rb in normal rat myocardial tissue and in tissue injured by ischaemic necrosis.
    Physiologia Bohemoslovaca, 1968, Volume: 17, Issue:5

    Topics: Animals; Coronary Vessels; Isoproterenol; Myocardial Infarction; Myocardium; Radioisotopes; Rats; Ru

1968
Myocardial connective tissue metabolism in response to injury. Histological and chemical studies of mucopolysaccharide and collagen in rat hearts after isoproterenol-induced infaraction.
    Circulation research, 1969, Volume: 25, Issue:2

    Topics: Animals; Arteriosclerosis; Cicatrix; Collagen; Connective Tissue; Female; Glycosaminoglycans; Hexosa

1969
Potassium, sodium and chlorides in the heart of rats with isoprenaline-induced experimental necrosis of the myocardium.
    Physiologia Bohemoslovaca, 1968, Volume: 17, Issue:1

    Topics: Animals; Chlorides; Electrolytes; Heart; Hyperkalemia; Isoproterenol; Male; Myocardial Infarction; M

1968
Sulfur 35 uptake in acid mucopolysaccharides of the rat heart following injury.
    The American journal of physiology, 1973, Volume: 224, Issue:2

    Topics: Animals; Blood Proteins; Cicatrix; Glycosaminoglycans; Isoproterenol; Male; Myocardial Infarction; M

1973
A study of system and regional hemodynamic changes in experimental myocardial infarction, with reference to the effects of catecholamine.
    Japanese circulation journal, 1974, Volume: 38, Issue:6

    Topics: Animals; Blood Pressure; Carotid Arteries; Catecholamines; Coronary Circulation; Coronary Vessels; D

1974
[Action of various vasoactive amines on the normal and pathological cardiac function, mainly cardiogenic shock].
    Bibliotheca cardiologica, 1966, Volume: 17

    Topics: Angiotensin II; Animals; Coronary Disease; Dogs; Electrocardiography; Epinephrine; Heart; Heart Rate

1966
[Auriculo-ventricular block during the acute phase of myocardial infarction. Apropos of 46 cases].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Jan-08, Volume: 45, Issue:2

    Topics: Adrenal Cortex Hormones; Arrhythmia, Sinus; Cerebral Ventriculography; Electric Stimulation; Electro

1969
[Thoughts on 125 cases of complete auriculo-ventricular blocks].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Jan-08, Volume: 45, Issue:2

    Topics: Aged; Atrial Fibrillation; Bradycardia; Cardiac Catheterization; Electric Countershock; Ephedrine; E

1969
Experimental left ventricular akinesis: results of excision.
    The Journal of thoracic and cardiovascular surgery, 1970, Volume: 60, Issue:5

    Topics: Acetylcholine; Angiocardiography; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cineangio

1970
Left ventricular akinesis: experimental production, haemodynamic effects, and results of excision.
    Cardiovascular research, 1972, Volume: 6, Issue:4

    Topics: Acetylcholine; Angiocardiography; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cineangio

1972
Editorial: Calcium responses ("calcium spikes").
    The American journal of cardiology, 1974, May-06, Volume: 33, Issue:5

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Coronary Disease; Cyclic AMP; E

1974
Effect of various types of sympathicolytics on isoproterenol-induced myocardial lesions.
    Acta physiologica Academiae Scientiarum Hungaricae, 1966, Volume: 29, Issue:1

    Topics: Animals; Dibenzylchlorethamine; Ethanolamines; Guanethidine; Heart; Isoproterenol; Myocardial Infarc

1966
[Group discussion: progress in cardiopathology].
    Naika. Internal medicine, 1971, Volume: 28, Issue:2

    Topics: Adrenergic beta-Antagonists; Coronary Angiography; Coronary Vessels; Extracorporeal Circulation; Glu

1971
[Influence of various drugs on infarct-like heart lesions induced in the rat by subcutaneous injections of isoproterenol].
    Bollettino chimico farmaceutico, 1972, Volume: 111, Issue:9

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics; Animals; Anti-Arrhythmia Agen

1972
[Prevention and therapy of arrhythmias due to myocardial infarct].
    Schweizerische medizinische Wochenschrift, 1972, Dec-16, Volume: 102, Issue:50

    Topics: Adrenergic beta-Antagonists; Ajmaline; Arrhythmias, Cardiac; Hemodynamics; Humans; Isoproterenol; My

1972
Blood-gas measurements in early diagnosis of shock and pulmonary edema complicating acute myocardial infarction. II. Oxygen tension in mixed venous blood, arterio-venous oxygen difference, and acid-base balance.
    Polish medical journal, 1972, Volume: 11, Issue:5

    Topics: Acid-Base Equilibrium; Adrenergic alpha-Antagonists; Arteries; Carbon Dioxide; Heart Failure; Humans

1972
The antiarrhythmic properties of UM-272, the dimethyl quaternary derivative of propranolol.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 184, Issue:1

    Topics: Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Anura; Arrhythmias, Cardiac; Cardanolides;

1973
Editorial: Accomplices in crime.
    JAMA, 1974, Aug-05, Volume: 229, Issue:6

    Topics: Acute Disease; Adenosine; Animals; Collateral Circulation; Coronary Circulation; Dogs; Drug Synergis

1974
Sinus bradycardia. Autonomic influences and clinical assessment.
    British heart journal, 1974, Volume: 36, Issue:8

    Topics: Adams-Stokes Syndrome; Adolescent; Adult; Aged; Atropine; Autonomic Nervous System; Bradycardia; Dip

1974
The pathophysiology of tachycardia-dependent paroxysmal atrioventricular block after acute myocardial ischemia. Experimental and clinical observations.
    Circulation, 1974, Volume: 50, Issue:3

    Topics: Adams-Stokes Syndrome; Aged; Animals; Bundle of His; Coronary Disease; Coronary Vessels; Disease Mod

1974
Effects of methylprednisolone administration in acute myocardial infarction.
    The American journal of cardiology, 1974, Volume: 34, Issue:6

    Topics: Adenylyl Cyclases; Animals; Calcium; Carotid Arteries; Cats; Coronary Circulation; Coronary Vessels;

1974
Progressive electrocardiographic changes in male and female arteriosclerotic and non-arteriosclerotic rats during the course of isoproterenol-induced myocardial infarction.
    Cardiovascular research, 1974, Volume: 8, Issue:4

    Topics: Animals; Arteriosclerosis; Breeding; Electrocardiography; Female; Heart; Heart Rate; Isoproterenol;

1974
Clinical appraisal of shock following acute myocardial infarction.
    Cardiology, 1974, Volume: 59, Issue:2

    Topics: Acid-Base Equilibrium; Aged; Anuria; Blood Pressure; Body Temperature; Central Venous Pressure; Conf

1974
Proceedings: The effects of practolol in the early stages of experimental myocardial infarction.
    British journal of pharmacology, 1974, Volume: 52, Issue:1

    Topics: Animals; Dogs; Heart; Heart Rate; Hemodynamics; Isoproterenol; Myocardial Infarction; Myocardium; Ox

1974
Failure of free fatty acids to influence degree of myocardial injury following acute coronary artery occlusion in pigs.
    Cardiology, 1974, Volume: 59, Issue:4

    Topics: Acute Disease; Animals; Blood Pressure; Coronary Disease; Fatty Acids, Nonesterified; Heart Rate; Is

1974
[A new method of evaluation of ventricular contractility].
    Bollettino della Societa italiana di cardiologia, 1974, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Cardiomyopathies; Child; Female; Heart Function Tests; Heart Valve Diseases; Hear

1974
Effects of isoproterenol, propranolol and artificial pacing on hemodynamics and energy liberation of the infarcted heart in dogs.
    Japanese heart journal, 1974, Volume: 15, Issue:6

    Topics: Animals; Blood Pressure; Coronary Vessels; Depression, Chemical; Dogs; Dose-Response Relationship, D

1974
Effect of beta receptor-stimulating drugs on the cardiovascular and respiratory function of critically ill patients with serious heart disorders.
    Resuscitation, 1974, Volume: 3, Issue:3

    Topics: Albuterol; Arrhythmias, Cardiac; Asthma; Blood Pressure; Cardiovascular System; Female; Heart; Heart

1974
[Experimental and clinical studies on effects of glucagon on the ischmic heart].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1974, Volume: 22, Issue:12

    Topics: Adolescent; Adult; Animals; Child; Coronary Disease; Dogs; Female; Glucagon; Heart; Humans; Isoprote

1974
Cardiac performance and metabolism in shock due to acute myocardial infarction in man: response to catecholomines and mechanical cardiac assist.
    Transactions of the New York Academy of Sciences, 1972, Volume: 34, Issue:4

    Topics: Aged; Blood Flow Velocity; Blood Pressure; Catecholamines; Coronary Circulation; Coronary Vessels; F

1972
[Atrioventricular blockade and its treatment in acute myocardial infarct].
    Kardiologiia, 1973, Volume: 13, Issue:4

    Topics: Acute Disease; Administration, Oral; Aged; Atropine; Electric Stimulation Therapy; Electrocardiograp

1973
Coronary revascularization in patients receiving propranolol.
    Circulation, 1974, Volume: 50, Issue:2 Suppl

    Topics: Angina Pectoris; Coronary Artery Bypass; Emergencies; Heart Rate; Heart Ventricles; Humans; Isoprote

1974
Right to left shunt in patients with acute myocardial infarction. A proposed mechanism.
    The American journal of cardiology, 1972, Volume: 29, Issue:6

    Topics: Blood Pressure; Body Surface Area; Carbon Dioxide; Cardiac Catheterization; Cardiac Output; Collater

1972
[Microcirculatory aspect of myocardial lesions induced by catecholamine infusion. Ultrastructural study with diffusion tracers. I. Isoproterenol].
    Pathologie-biologie, 1973, Volume: 21, Issue:8

    Topics: Animals; Coronary Circulation; Diffusion; Ferritins; Heart; Isoproterenol; Microcirculation; Microsc

1973
Simple and safe bedside method for serial measurement of left ventricular ejection fraction, cardiac output, and pulmonary blood volume.
    British heart journal, 1974, Volume: 36, Issue:2

    Topics: Blood Volume Determination; Bronchial Neoplasms; Cardiac Catheterization; Cardiac Output; Heart; Hea

1974
Immunofluorescent studies in isoproterenol-induced myocardial necrosis in rats.
    Experientia, 1974, Apr-15, Volume: 30, Issue:4

    Topics: Animals; Antibodies; Disease Models, Animal; Fluorescent Antibody Technique; Injections, Subcutaneou

1974
[Potassium variations in the coronary sinus after circumflex artery ligation. Effects of premedication with isoproteronol and of ventilation with a helium mixture].
    Archives des maladies du coeur et des vaisseaux, 1972, Volume: 65, Issue:8

    Topics: Acute Disease; Animals; Arteries; Coronary Circulation; Dogs; Heart; Helium; Hydrogen-Ion Concentrat

1972
Effect of isoproterenol on the abnormal T wave.
    The American journal of cardiology, 1972, Volume: 30, Issue:8

    Topics: Action Potentials; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atropine; Diagnosis, Differential;

1972
[Myocardial damage following overdosage with isoprenaline aerosol spray].
    Ugeskrift for laeger, 1972, Dec-04, Volume: 134, Issue:49

    Topics: Adult; Aerosols; Asthma; Female; Humans; Isoproterenol; Myocardial Infarction; Respiratory Therapy;

1972
[Myocardial infarct: possibilities and limitations of intensive care].
    Schweizerische medizinische Wochenschrift, 1972, Dec-16, Volume: 102, Issue:50

    Topics: Aged; Blood Pressure; Cardiac Output; Coronary Care Units; Dopamine; Heart Rate; Humans; Isoproteren

1972
Force-velocity and hydraulic indices in analysis of normal and marginally ischemic myocardium: effects of isoproterenol and levarteronal (norepinephrine) infusion.
    Surgical forum, 1972, Volume: 23, Issue:0

    Topics: Animals; Cardiac Output; Coronary Circulation; Dogs; Heart Ventricles; Ischemia; Isoproterenol; Myoc

1972
Pathophysiologic changes in arteriosclerotic and nonarteriosclerotic rats, following isoproterenol-induced myocardial infarction.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Adrenal Glands; Alanine Transaminase; Aldosterone; Animals; Arteriosclerosis; Aspartate Aminotransfe

1972
Myocardial loss of functional magnesium. II. In cardiomyopathies of diverse etiology.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Adult; Age Factors; Aging; Animals; Calcium; Cricetinae; Heart; Heart Diseases; Heart Failure; Human

1972
Complete heart block in acute myocardial infarction: drug therapy.
    American heart journal, 1973, Volume: 85, Issue:2

    Topics: Arrhythmias, Cardiac; Atropine; Evaluation Studies as Topic; Glucocorticoids; Heart Block; Heart Fai

1973
Deleterious effects of increased heart rate on infarct size in the conscious dog.
    The American journal of cardiology, 1973, Volume: 31, Issue:4

    Topics: Animals; Atropine; Constriction; Coronary Vessels; Creatine Kinase; Dogs; Heart Block; Heart Rate; I

1973
[Isuprel and electrodiagnosis of coronary insufficiency].
    Schweizerische medizinische Wochenschrift, 1973, Mar-03, Volume: 103, Issue:9

    Topics: Adult; Angina Pectoris; Coronary Disease; Electrocardiography; Female; Humans; Isoproterenol; Male;

1973
Effect of inhibition of lipolysis on infarct size after experimental coronary artery occlusion.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:7

    Topics: Animals; Blood Pressure; Coronary Circulation; Creatine Kinase; Dogs; Electrocardiography; Fatty Aci

1973
Interrelation between alterations in pulmonary mechanics and hemodynamics in acute myocardial infarction.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:8

    Topics: Acute Disease; Adult; Aged; Airway Obstruction; Airway Resistance; Blood Pressure; Body Water; Femal

1973
[Method of epicardial ECG registration].
    Zeitschrift fur Kardiologie, 1973, Volume: 62, Issue:5

    Topics: Animals; Coronary Disease; Dipyridamole; Dogs; Electrocardiography; Heart; Isoproterenol; Ligation;

1973
Early estimation of myocardial damage in conscious dogs and patients with evolving acute myocardial infarction.
    The Journal of clinical investigation, 1973, Volume: 52, Issue:10

    Topics: Acute Disease; Animals; Arterial Occlusive Diseases; Arteries; Coronary Vessels; Creatine Kinase; Do

1973
Prophylactic uses of antiarrhythmic drugs in acute myocardial infarction.
    Postgraduate medicine, 1973, Volume: 54, Issue:4

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Humans; Injections, Intravenous; Isoproteren

1973
Investigations on protection of the ischemic myocardium.
    Transactions of the American Clinical and Climatological Association, 1973, Volume: 84

    Topics: Animals; Assisted Circulation; Creatine Kinase; Digitalis Glycosides; Dogs; Electrocardiography; Glu

1973
Drug-induced changes in blood flow in normal and ischaemic regions of the canine myocardium.
    British journal of pharmacology, 1973, Volume: 47, Issue:3

    Topics: Amino Alcohols; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dipyridamole; Dogs;

1973
Drug therapy in cardiogenic shock.
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 7, Issue:2

    Topics: Cardiac Output; Digitalis Glycosides; Dopamine; Glucagon; Hemodynamics; Humans; Isoproterenol; Metap

1973
Changes in myocardial thiamine in arteriosclerotic and non-arteriosclerotic rats subjected to isoprenaline induced myocardial infarction.
    British journal of experimental pathology, 1973, Volume: 54, Issue:5

    Topics: Adrenal Glands; Animals; Arteriosclerosis; Breeding; Female; Isoproterenol; Kidney; Male; Myocardial

1973
Effect of exercise on arrhythmias following experimental acute myocardial infarction.
    Angiology, 1973, Volume: 24, Issue:11

    Topics: Animals; Coronary Vessels; Dogs; Electrocardiography; Exercise Test; Heart Ventricles; Isoproterenol

1973
Effects of glucagon and isoproterenol on severity of acute myocardial ischemic injury.
    Scandinavian journal of clinical and laboratory investigation, 1973, Volume: 32, Issue:2

    Topics: Alcohols; Animals; Blood Pressure; Coronary Disease; Depression, Chemical; Dogs; Electrocardiography

1973
[Diagnostic test using isoproterenol after myocardial infarct. Preliminary report].
    Schweizerische medizinische Wochenschrift, 1973, Dec-15, Volume: 103, Issue:50

    Topics: Adult; Aged; Angiography; Coronary Angiography; Electrocardiography; Exercise Test; Humans; Isoprote

1973
Calorigenic effects of isoproterenol during production of myocardial necrosis in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Oct-01, Volume: 144, Issue:1

    Topics: Animals; Heart Diseases; Isoproterenol; Male; Metabolism; Motor Activity; Muscle Contraction; Myocar

1973
[Method for hemodynamic and metabolic evaluation of patients needing intensive therapy. In reference to the experiences of Dr. Siegel and coworkers].
    Minerva anestesiologica, 1973, Volume: 39, Issue:11

    Topics: Glucagon; Heart Failure; Hemodynamics; Humans; Intensive Care Units; Isoproterenol; Liver Cirrhosis;

1973
Quantitative biochemical changes in rats following isoproterenol-induced myocardial infarction.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:11

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Proteins; Bl

1973
[Studies on the therapy of shock in acute myocardial infarct].
    Bollettino della Societa italiana di cardiologia, 1973, Volume: 18, Issue:2

    Topics: Acute Disease; Aged; Dopamine; Female; Humans; Isoproterenol; Male; Middle Aged; Myocardial Infarcti

1973
Treatment of nontraumatic cardiac emergencies.
    Postgraduate medicine, 1974, Volume: 55, Issue:1

    Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Electric Countershock; Emergency

1974
Myocardial glycoprotein changes with isoproterenol-induced necrosis and repair in the rat.
    The American journal of physiology, 1974, Volume: 226, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Glycoproteins; Isoproterenol; Myocardial Infarction; Myocardiu

1974
Adrenocortical changes associated with methylandrostenediol-induced hypertension and isoproterenol-induced myocardial infarction in arteriosclerotic versus nonarteriosclerotic rats.
    Laboratory investigation; a journal of technical methods and pathology, 1974, Volume: 30, Issue:3

    Topics: Adrenal Glands; Anabolic Agents; Animals; Aorta; Arteriosclerosis; Cholesterol; Corticosterone; Fema

1974
Modification of experimental myocardial infarct size by cardiac drugs.
    The American journal of cardiology, 1974, Volume: 33, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Catheterization; Cardiac Volume; Coronary Circulation; Coronary Ves

1974
Isoproterenol-induced myocardial infarction in the gerbil (Meriones unguiculatus).
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:3

    Topics: Adrenal Glands; Animals; Blood Glucose; Blood Urea Nitrogen; Cholesterol; Creatine Kinase; Disease M

1974
The demonstration of energy dependence of the isoproterenol-induced transcellular Ca2+ current in isolated perfused guinea pig hearts--an explanation for mechanical failure of ischemic myocardium.
    The Journal of surgical research, 1974, Volume: 16, Issue:4

    Topics: Action Potentials; Animals; Biological Transport; Caffeine; Calcium; Cell Membrane; Cell Membrane Pe

1974
[Myocardial necrosis induced with isoproterenol in rat heart].
    Acta pharmaceutica Hungarica, 1974, Volume: 44, Issue:1

    Topics: Animals; Carbon Radioisotopes; Heart; Hypoxia; Isoproterenol; Myocardial Infarction; Myocardium; Nec

1974
Effect of exercise on myocardial infarction in young vs. old male rats: electrocardiograph changes.
    American heart journal, 1974, Volume: 88, Issue:3

    Topics: Age Factors; Alanine Transaminase; Animals; Aspartate Aminotransferases; Creatine Kinase; Electrocar

1974
Vasopressors for treating shock.
    Postgraduate medicine, 1974, Volume: 56, Issue:2

    Topics: Bacteria; Chloramphenicol; Epinephrine; Humans; Isoproterenol; Metaraminol; Methoxamine; Morphine; M

1974
[Clinics and therapy of schock in myocardial infarct].
    Cardiologia pratica, 1969, Volume: 20, Issue:5

    Topics: Digitalis Glycosides; Electrocardiography; Epinephrine; Heart Arrest; Humans; Isoproterenol; Mephent

1969
[Clinical and experimental studies on the immunologic aspects of myocardial infarct].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Jan-01, Volume: 25, Issue:1

    Topics: Agglutination Tests; Anemia; Angina Pectoris; Animals; Antibody Formation; Antigen-Antibody Reaction

1970
Myocardial infarction following coronary ligation in dogs. Hemodynamic effects of isoproterenol and acetylstrophanthidin.
    Circulation research, 1967, Volume: 21, Issue:2

    Topics: Animals; Coronary Vessels; Dogs; Female; Heart; Hemodynamics; Isoproterenol; Ligation; Male; Myocard

1967
[Auricular standstill. Apropos of 4 cases with endocavitary or esophageal leads].
    Archives des maladies du coeur et des vaisseaux, 1967, Volume: 60, Issue:6

    Topics: Aged; Arrhythmias, Cardiac; Atrial Flutter; Electric Countershock; Electrocardiography; Heart Atria;

1967
A coronary care unit: results of the first year of operation.
    The Medical journal of Australia, 1968, Mar-23, Volume: 1, Issue:12

    Topics: Acute Disease; Adult; Aged; Anticoagulants; Arrhythmias, Cardiac; Digitoxin; Electrocardiography; Fe

1968
[Treatment of conduction disorders associated with the acute phase of infarct].
    Archives des maladies du coeur et des vaisseaux, 1968, Volume: 61, Issue:1

    Topics: Acute Disease; Adult; Electrocardiography; Female; Heart Block; Humans; Hydrocortisone; Injections,

1968
[Quantitative and qualitative investigations on the myosin of the rat heart using polarization microscopy].
    Virchows Archiv. B, Cell pathology, 1969, Sep-16, Volume: 3, Issue:4

    Topics: Animals; Edema; Heart; Isoproterenol; Male; Microscopy, Polarization; Muscle Proteins; Myocardial In

1969
[Protective action of a delayed preparation of trinitroglycerin on experimental cardiac infarct induced by isoproterenol in rats].
    Bollettino chimico farmaceutico, 1969, Volume: 108, Issue:9

    Topics: Animals; Isoproterenol; Male; Myocardial Infarction; Nitroglycerin; Rats

1969
[Hemodynamic study of shock in myocardial infarct].
    Archives des maladies du coeur et des vaisseaux, 1971, Volume: 64, Issue:6

    Topics: Aged; Digoxin; Female; Glucagon; Hemodynamics; Humans; Isoproterenol; Male; Myocardial Infarction; S

1971
Clinical studies on apexcardiogram. II. Cardiac movement in thyroid dysfunction and coronary heart disease from the point of apexcardiogram.
    Japanese circulation journal, 1971, Volume: 35, Issue:9

    Topics: Adolescent; Adult; Angina Pectoris; Arteriosclerosis; Coronary Disease; Electrocardiography; Female;

1971
Hemodynamic evaluation of left ventricular function in shock complicating myocardial infarction.
    Circulation, 1972, Volume: 45, Issue:1

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Dextrans; Digoxin; Electrocardiography; Epinephrine; He

1972
On relationships between synthesis of DNA and incorporation of deoxythymidine into DNA during myocardial infarctions induced in rats by isoproterenol.
    Chemico-biological interactions, 1972, Volume: 4, Issue:4

    Topics: Adenine; Animals; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Cytosine; DNA; Female; Formates; G

1972
Effect of isoproterenol,l-norepinephrine, and intraaortic counterpulsation on hemodynamics and myocardial metabolism in shock following acute myocardial infarction.
    Circulation, 1972, Volume: 45, Issue:2

    Topics: Acute Disease; Aged; Aorta; Assisted Circulation; Blood Pressure; Cardiac Output; Coronary Circulati

1972
Myocardial and plasma lactate changes in arteriosclerotic and non-arteriosclerotic rats during isoproterenol-induced infarction.
    Angiology, 1972, Volume: 23, Issue:1

    Topics: Animals; Arteriosclerosis; Autopsy; Female; Isoproterenol; Lactates; Male; Myocardial Infarction; My

1972
Validity of isoproterenol-induced myocardial lactate production: an internal control.
    American heart journal, 1972, Volume: 83, Issue:1

    Topics: Cardiac Catheterization; Heart; Humans; Isoproterenol; Lactates; Myocardial Infarction; Myocardium;

1972
Cardiac arrhythmias in anesthesia and in acute myocardial infarction.
    International anesthesiology clinics, 1972,Spring, Volume: 10, Issue:1

    Topics: Anesthesia; Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Electrocardiography;

1972
Experimental cardiac necrosis in the Japanese quail (Cotournix cotournix).
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:4

    Topics: Animals; Birds; Body Weight; Female; Heart; Isoproterenol; Male; Myocardial Infarction; Sex Factors;

1972
Mortality of heart block complicating acute myocardial infarction managed without artificial pacemakers.
    Acta medica Scandinavica, 1972, Volume: 191, Issue:5

    Topics: Aged; Electrocardiography; Female; Glucose; Heart Block; Humans; Insulin; Isoproterenol; Male; Middl

1972
Effects of intraaortic balloon counterpulsation on the severity of myocardial ischemic injury following acute coronary occlusion. Counterpulsation and myocardial injury.
    Circulation, 1972, Volume: 45, Issue:6

    Topics: Acute Disease; Animals; Assisted Circulation; Coronary Circulation; Coronary Disease; Coronary Vesse

1972
Haemodynamic effects of isoprenaline in acute myocardial infarction.
    British heart journal, 1972, Volume: 34, Issue:7

    Topics: Acute Disease; Adult; Blood Pressure; Cardiac Output; Cardiac Volume; Female; Heart Failure; Heart R

1972
Precordial S-T segment elevation mapping: an atraumatic method for assessing alterations in the extent of myocardial ischemic injury. The effects of pharmacologic and hemodynamic interventions.
    The American journal of cardiology, 1972, Volume: 29, Issue:2

    Topics: Animals; Arteries; Blood Pressure; Coronary Vessels; Dogs; Electrocardiography; Female; Heart Rate;

1972
[Experimental study on drugs for the treatment of myocardial infarction].
    Japanese circulation journal, 1972, Volume: 36, Issue:1

    Topics: Angiography; Animals; Benzyl Compounds; Body Weight; Carboxylic Acids; Dipyridamole; Disease Models,

1972
Quantification of function in normal and infarcted regions of the left ventricle.
    Cardiovascular research, 1972, Volume: 6, Issue:5

    Topics: Animals; Biometry; Blood Pressure; Cineradiography; Electrocardiography; Female; Heart; Heart Ventri

1972
Calcium as mediator of isoproterenol-induced myocardial necrosis.
    The American journal of pathology, 1972, Volume: 69, Issue:3

    Topics: Animals; Calcium; Heart; Injections, Intraperitoneal; Isoproterenol; Myocardial Infarction; Myocardi

1972
Acute enzyme and metabolic changes in arteriosclerotic vs nonarteriosclerotic rats following isoproterenol-induced myocardial infarction.
    Angiology, 1971, Volume: 22, Issue:5

    Topics: Alanine Transaminase; Animals; Arteriosclerosis; Aspartate Aminotransferases; Blood Glucose; Blood U

1971
Clinical experience with a new cardiac assist device. The dual-chambered intra-aortic balloon assist.
    The Journal of thoracic and cardiovascular surgery, 1971, Volume: 62, Issue:4

    Topics: Aorta; Cardiac Output; Coronary Vessels; Extracorporeal Circulation; Glucagon; Heart-Lung Machine; H

1971
Cigarette smoke: effects on lactate extraction in the presence of severe coronary atherosclerosis.
    American heart journal, 1971, Volume: 82, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Animals; Arrhythmias, Cardiac; Cardiac Catheterization; Coronary Disea

1971
Sinus arrest in acute myocardial infarction.
    British heart journal, 1971, Volume: 33, Issue:5

    Topics: Adult; Aged; Arrhythmia, Sinus; Electrocardiography; Female; Heart Arrest; Humans; Hypotension; Inje

1971
Effect of isoproterenol on rat plasma creatine phosphokinase activity.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 194, Issue:1

    Topics: Animals; Creatine Kinase; Isoenzymes; Isoproterenol; Male; Muscles; Myocardial Infarction; Myocardiu

1971
[Cardiogenic shock].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1971, Jul-01, Volume: 26, Issue:13

    Topics: Cardiac Volume; Digitalis Glycosides; Heart Rate; Hemodynamics; Humans; Isoproterenol; Myocardial In

1971
Metabolic and histopathological consequences of a fatty liver during the acute stages of myocardial infarction in rats.
    British journal of experimental pathology, 1971, Volume: 52, Issue:5

    Topics: Acute Disease; Adrenal Glands; Alanine Transaminase; Aldosterone; Animals; Aspartate Aminotransferas

1971
Quantitative assessment of the extent of myocardial infarction in the conscious dog by means of analysis of serial changes in serum creatine phosphokinase activity.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:12

    Topics: Animals; Blood Flow Velocity; Cardiac Output; Constriction; Coronary Vessels; Creatine Kinase; Dogs;

1971
[Result report of a control by an apparatus of 208 myocardial infarct patients in an intensive care station. Preliminary report].
    Wiener medizinische Wochenschrift (1946), 1971, Jun-19, Volume: 121, Issue:25

    Topics: Adult; Aged; Arrhythmias, Cardiac; Atropine; Austria; Digitalis Glycosides; Electric Countershock; E

1971
Treatment of arrhythmias associated with acute myocardial infarction.
    The Nebraska medical journal, 1971, Volume: 56, Issue:12

    Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Humans; Isoproterenol; Lidocaine;

1971
[Intracellular overloading with calcium as a decisive causative factor in the pathogenesis of noncoronary myocardial necroses].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1971, Volume: 37

    Topics: Animals; Calcium; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Rats

1971
Myocardial resistance to isoprenaline in rats: variations with time.
    The Journal of pathology, 1971, Volume: 105, Issue:4

    Topics: Animals; Body Weight; Coronary Vessels; Drug Resistance; Heart; Injections, Subcutaneous; Isoprotere

1971
Serum enzyme activities following administration of purified basic proteins from rattlesnake venoms.
    Chemico-biological interactions, 1971, Volume: 4, Issue:1

    Topics: Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Blood Proteins; Enzyme Induction; Fructo

1971
Study on the idiopathic cardiomyopathy. Diagnostic value of the apexcardiogram, 131 Cs scintiscanning of the heart and plasma hydroxyproline.
    Japanese circulation journal, 1971, Volume: 35, Issue:7

    Topics: Adult; Amyl Nitrite; Autopsy; Cardiomyopathies; Cesium Isotopes; Child; Collagen; Collagen Diseases;

1971
Acute coronary care: a year's experience at Napier Hospital.
    The New Zealand medical journal, 1968, Volume: 67, Issue:431

    Topics: Anticoagulants; Arrhythmias, Cardiac; Atropine; Digoxin; Electric Countershock; Heart Arrest; Humans

1968
Experimental studies on the healing of cardiac necrosis.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Connective Tissue; Female; Isoproterenol; Ligation; Male; Myocardial Infarction; Myocardium

1969
Experimental "metabolic" cardiopathies and their relationship to human heart diseases. Concluding remarks.
    Annals of the New York Academy of Sciences, 1969, Jan-31, Volume: 156, Issue:1

    Topics: Animals; Cardiomyopathies; Heart Diseases; Heart Failure; Humans; Ischemia; Isoproterenol; Myocardia

1969
The significance of atrial rate in patients with atrioventricular conduction abnormalities complicating acute myocardial infarction.
    The American journal of cardiology, 1969, Volume: 24, Issue:5

    Topics: Adult; Aged; Atropine; Carotid Sinus; Electrocardiography; Female; Heart Atria; Heart Block; Heart C

1969
[Problems in the treatment of cardiogenic shock in myocardial infarct].
    Medicina interna, 1969, Volume: 21, Issue:11

    Topics: Assisted Circulation; Humans; Isoproterenol; Morphine; Myocardial Infarction; Oxygen; Plasma Substit

1969
Management of acute myocardial infarction complicated by advanced atrioventricular block. Role of artificial pacing.
    The American journal of cardiology, 1969, Volume: 23, Issue:1

    Topics: Adult; Aged; Arrhythmias, Cardiac; Electrocardiography; Heart Block; Humans; Isoproterenol; Middle A

1969
Treatment of shock following myocardial infarction.
    Journal of the Iowa Medical Society, 1969, Volume: 59, Issue:8

    Topics: Atropine; Cardiac Glycosides; Furosemide; Humans; Isoproterenol; Metaraminol; Myocardial Infarction;

1969
Serum creatine phosphokinase activity following isoproterenol-induced myocardial infarction in male and female rats with and without arteriosclerosis.
    American heart journal, 1970, Volume: 79, Issue:1

    Topics: Animals; Arteriosclerosis; Creatine Kinase; Female; Isoproterenol; Male; Myocardial Infarction; Orga

1970
The effects of dimethylsulfoxide (DMSO) on the healing of experimental myocardial necrosis.
    American heart journal, 1970, Volume: 79, Issue:3

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Isoproterenol; Male; Myocardial Infarction; Myo

1970
[Central venous pressure].
    La Presse medicale, 1970, Feb-25, Volume: 78, Issue:10

    Topics: Aged; Blood Pressure Determination; Blood Volume; Central Venous Pressure; Digitalis; Diuretics; Hum

1970
Hemodynamics, coronary blood flow, and myocardial metabolism in coronary shock; response of 1-norepinephrine and isoproterenol.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:10

    Topics: Aged; Arteries; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Female; Heart; Hemodynamics;

1970
[Use of isoproterenol in patients with myocardial infarction].
    Masui. The Japanese journal of anesthesiology, 1970, Volume: 19, Issue:2

    Topics: Aged; Humans; Isoproterenol; Male; Myocardial Infarction

1970
Treatment of acute myocardial infarction. 3. Bradyarrhythmias.
    Postgraduate medicine, 1970, Volume: 48, Issue:2

    Topics: Acute Disease; Arrhythmias, Cardiac; Atropine; Bradycardia; Heart Block; Heart Massage; Humans; Isop

1970
Experimental myocardial infarction. V. Reaction to impaired circumflex flow in the presence of established anterior myocardial infarction in intact conscious dogs.
    The American journal of cardiology, 1970, Volume: 26, Issue:4

    Topics: Animals; Cardiac Output; Coronary Disease; Coronary Vessels; Dogs; Heart; Heart Rate; Hypotension; I

1970
Thiamine deficiency and experimental cardiac necrosis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 135, Issue:3

    Topics: Animals; Isoproterenol; Myocardial Infarction; Rats; Thiamine Deficiency

1970
Isoproterenol-induced myocardial infarction in rats. Distribution of corticosterone.
    Circulation research, 1970, Volume: 27, Issue:6

    Topics: Adrenal Glands; Animals; Brain Chemistry; Carbon Isotopes; Chromatography; Corticosterone; Dialysis;

1970
[Current treatment of atrioventricular conduction disorders].
    Medicina interna, 1970, Volume: 22, Issue:12

    Topics: Anti-Inflammatory Agents; Atropine; Ephedrine; Heart Block; Humans; Isoproterenol; Lactates; Metapro

1970
[Model of cardiogenic collapse (shock) in experimental myocardial infarct].
    Kardiologiia, 1970, Volume: 10, Issue:12

    Topics: Animals; Cats; Coronary Disease; Coronary Vessels; Isoproterenol; Myocardial Infarction; Shock, Card

1970
Stimulation of DNA synthesis and AMP deaminase activity in rat hearts during isoproterenol-induced myocardial infarction.
    Chemico-biological interactions, 1970, Volume: 2, Issue:3

    Topics: Adenosine Monophosphate; Aminohydrolases; Animals; DNA; DNA Repair; Female; Heart Atria; Heart Ventr

1970
Factors influencing infarct size following experimental coronary artery occlusions.
    Circulation, 1971, Volume: 43, Issue:1

    Topics: Animals; Blood Pressure; Bretylium Compounds; Coronary Disease; Creatine Kinase; Dogs; Electric Stim

1971
Myocardial and serum lactate changes during isoproterenol-induced infarction.
    American heart journal, 1971, Volume: 81, Issue:4

    Topics: Acidosis; Animals; Coronary Vessels; Glycolysis; Isoproterenol; Lactates; Male; Myocardial Infarctio

1971
Bretylium tosylate in the management of refractory ventricular fibrillation.
    Canadian Medical Association journal, 1971, Jul-24, Volume: 105, Issue:2

    Topics: Adult; Age Factors; Aged; Angina Pectoris; Aortic Valve Insufficiency; Aortic Valve Stenosis; Bretyl

1971
Conservative treatment of AV block in acute myocardial infarction. Results in 105 consecutive patients.
    British heart journal, 1971, Volume: 33, Issue:4

    Topics: Acute Disease; Adult; Aged; Bundle-Branch Block; Female; Heart Block; Humans; Injections, Intravenou

1971
Cineangiography of the coronary arteries: clinical function and anatomic correlation in patients with chronic chest pain.
    Canadian Medical Association journal, 1971, Aug-07, Volume: 105, Issue:3

    Topics: Adult; Age Factors; Angina Pectoris; Arteries; Blood Pressure; Cardiac Catheterization; Cardiac Outp

1971
[Therapy of acute myocardial infarct with particular reference to arrhythmia and myocardial contractibility disorders].
    Giornale di gerontologia, 1971, Volume: 19, Issue:1

    Topics: Adult; Aged; Aging; Arrhythmias, Cardiac; Atropine; Cardiac Glycosides; Cortisone; Electric Counters

1971
Plasma insulin in heart disease.
    Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:5

    Topics: Cardiac Surgical Procedures; Heart Diseases; Heart Failure; Humans; Insulin; Insulin Secretion; Isop

1971
[Atrio-ventricular block in acute myocardial infarct].
    Giornale italiano di cardiologia, 1971, Volume: 1, Issue:2

    Topics: Adrenal Cortex Hormones; Arrhythmias, Cardiac; Atropine; Electrocardiography; Heart Block; Humans; I

1971
Effect of decapitation on blood levels of creatine phosphokinase.
    American heart journal, 1971, Volume: 82, Issue:1

    Topics: Amputation, Surgical; Animals; Creatine Kinase; Female; Head; Isoproterenol; Male; Methods; Myocardi

1971
[Therapy of cardiogenic shock after heart infarct].
    Schweizerische medizinische Wochenschrift, 1967, Mar-25, Volume: 97, Issue:12

    Topics: Bicarbonates; Dextrans; Digitalis Glycosides; Humans; Isoproterenol; Morphine; Myocardial Infarction

1967
[Indications for the parenteral administration of isoproterenol].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1967, Dec-01, Volume: 22, Issue:23

    Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Asthma; Electrocardiography; Heart Arrest; Heart Rate;

1967
[Fluorescence microscopic and enzyme histochemical findings in toxically induced heart muscle necrosis].
    Gegenbaurs morphologisches Jahrbuch, 1967, Volume: 111, Issue:1

    Topics: Animals; Coronary Disease; Cytoplasmic Granules; Diagnosis, Differential; Heart; Histocytochemistry;

1967
Artificial pacing in management of complete heart block complicating acute myocaerdial infarction.
    British medical journal, 1968, Apr-20, Volume: 2, Issue:5598

    Topics: Glucose; Heart Block; Humans; Insulin; Isoproterenol; Methods; Myocardial Infarction; Pacemaker, Art

1968
Reducing mortality in myocardial infarction.
    Geriatrics, 1968, Volume: 23, Issue:4

    Topics: Arrhythmias, Cardiac; Electrocardiography; Heart Arrest; Humans; Hydrocortisone; Isoproterenol; Lido

1968
Comparison of norepinephrine and isoproterenol in experimental coronary shock. Observations on the effects of dextran infusion.
    American heart journal, 1968, Volume: 75, Issue:5

    Topics: Animals; Cardiac Output; Dextrans; Dogs; Embolism; Hemodynamics; Isoproterenol; Lidocaine; Myocardia

1968
Electrical pacing for heart block complicating acute myocardial infarction.
    The Medical journal of Australia, 1968, Mar-23, Volume: 1, Issue:12

    Topics: Acute Disease; Adams-Stokes Syndrome; Aged; Arrhythmias, Cardiac; Cardiac Catheterization; Cardiac O

1968
[Beta-receptor stimulation in infarction shock?].
    Deutsche medizinische Wochenschrift (1946), 1968, Volume: 93, Issue:23

    Topics: Humans; Isoproterenol; Myocardial Infarction; Resorcinols; Sympathomimetics

1968
Treatment of bradycardia and hypotension syndrome in patients with acute myocardial infarction.
    American heart journal, 1968, Volume: 75, Issue:6

    Topics: Atropine; Blood Pressure; Bradycardia; Cardiac Output; Hemodynamics; Humans; Hypotension; Isoprotere

1968
Complete heart block complicating myocardial infarction: experience with 33 patients.
    Australasian annals of medicine, 1968, Volume: 17, Issue:1

    Topics: Adams-Stokes Syndrome; Adult; Aged; Aspartate Aminotransferases; Atropine; Cardiac Catheterization;

1968
Therapy of atrioventricular block.
    The New England journal of medicine, 1968, Oct-10, Volume: 279, Issue:15

    Topics: Atropine; Digitalis Glycosides; Electrocardiography; Heart Block; Heart Conduction System; Humans; I

1968
Cardiac tamponade as a result of infusion. A complication of transvenous pacing.
    JAMA, 1968, Mar-18, Volume: 203, Issue:12

    Topics: Cardiac Tamponade; Electrocardiography; Heart Failure; Humans; Isoproterenol; Male; Middle Aged; Myo

1968
Obstetrical anesthesia in myocardial infarction and complete heart block.
    JAMA, 1968, May-13, Volume: 204, Issue:7

    Topics: Adult; Anesthesia, Obstetrical; Female; Heart Block; Humans; Isoproterenol; Myocardial Infarction; P

1968
[Behavior of some enzymatic activities of the myocardium and blood in infarct caused by isoproterenol].
    Atti della Societa italiana di cardiologia, 1968, Volume: 2

    Topics: Animals; Aspartate Aminotransferases; Clinical Enzyme Tests; Creatine Kinase; Fructose-Bisphosphate

1968
Myocardial necrosis induced by isoproterenol in rats. Changes in serum protein, lipoprotein, lipids and glucose druing active necrosis and repair in arteriosclerotic and nonarteriosclerotic animals.
    Angiology, 1968, Volume: 19, Issue:12

    Topics: Animals; Blood Glucose; Blood Proteins; Fatty Liver; Female; Isoproterenol; Lipids; Lipoproteins; Ma

1968
[Central venous pressure in control of cardiogenic shock].
    Medicina interna, 1968, Volume: 20, Issue:11

    Topics: Arrhythmias, Cardiac; Blood Pressure; Cardiac Tamponade; Digitalis Glycosides; Humans; Isoproterenol

1968
[Myocardial infarct and disorders of cardiac rhythm].
    L'union medicale du Canada, 1968, Volume: 97, Issue:12

    Topics: Arrhythmias, Cardiac; Coronary Care Units; Humans; Isoproterenol; Lidocaine; Myocardial Infarction;

1968
Current status of the treatment of shock complicating acute myocardial infarction.
    The Journal of trauma, 1969, Volume: 9, Issue:2

    Topics: Digitalis Glycosides; Dopamine; Humans; Hydrocortisone; Hyperbaric Oxygenation; Hypotension; Isoprot

1969
Effects of isoproterenol on hemodynamic alterations, myocardial metabolism, and coronary flow in experimental acute myocardial infarction with shock.
    American heart journal, 1969, Volume: 77, Issue:6

    Topics: Animals; Blood Pressure; Cardiac Output; Coronary Vessels; Dogs; Electrocardiography; Embolism; Hear

1969
[On the therapy of shock using isoprenaline].
    Deutsche medizinische Wochenschrift (1946), 1969, Apr-11, Volume: 94, Issue:15

    Topics: Adult; Aged; Aortic Aneurysm; Barbiturates; Blood Volume; Cardiac Output; Female; Humans; Isoprotere

1969
Acute changes in liver lipids during myocardial infarction induced by isoproterenol.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 130, Issue:4

    Topics: Animals; Cholesterol; Injections, Subcutaneous; Isoproterenol; Lipids; Liver; Male; Myocardial Infar

1969
[Stimulation of b-receptors in infarct shock].
    Minerva cardioangiologica, 1969, Volume: 17, Issue:1

    Topics: Humans; Isoproterenol; Metaproterenol; Myocardial Infarction; Resorcinols; Shock, Traumatic

1969
Treatment of shock associated with myocardial infarction.
    The Medical letter on drugs and therapeutics, 1969, Apr-04, Volume: 11, Issue:7

    Topics: Albumins; Arrhythmias, Cardiac; Dextrans; Digitalis Glycosides; Dopamine; Heart-Lung Machine; Humans

1969
Aortic pressure loading in dogs with myocardial infarction.
    American heart journal, 1969, Volume: 77, Issue:1

    Topics: Animals; Aorta; Blood Pressure; Cardanolides; Cardiac Catheterization; Cardiac Output; Coronary Vess

1969
Treatment of arrhythmias in myocardial infarction.
    Archives of internal medicine, 1969, Volume: 124, Issue:1

    Topics: Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Electric Countershock; Electrocar

1969
[Cardiogenic shock following myocardial infarct. Therapeutic results with isoprenaline and low-molecular dextran].
    Deutsche medizinische Wochenschrift (1946), 1969, Aug-15, Volume: 94, Issue:33

    Topics: Aged; Dextrans; Female; Humans; Isoproterenol; Male; Middle Aged; Molecular Weight; Myocardial Infar

1969
Glucagon: its enhancement of atrioventricular nodal pacemaker activity and failure to increase ventricular automaticity in dogs.
    Circulation research, 1969, Volume: 25, Issue:2

    Topics: Animals; Dogs; Glucagon; Heart Block; Heart Conduction System; Heart Ventricles; Hemostasis; Isoprot

1969
Myocardial contractility following cardiopulmonary bypass with and without myocardial ischemia.
    The Annals of thoracic surgery, 1969, Volume: 8, Issue:3

    Topics: Animals; Coronary Vessels; Dogs; Extracorporeal Circulation; Heart; Heart Ventricles; Ischemia; Isop

1969
Myocardial revascularization with internal mammary artery implantation: current status.
    JAMA, 1969, Feb-03, Volume: 207, Issue:5

    Topics: Aneurysm; Angina Pectoris; Angiography; Arteriosclerosis; Blood Flow Velocity; Collateral Circulatio

1969
Reevaluation of the treatment of shock secondary to cardiac infarction.
    Diseases of the chest, 1969, Volume: 56, Issue:3

    Topics: Adrenal Cortex Hormones; Animals; Blood Flow Velocity; Blood Pressure; Blood Volume; Cardiac Output;

1969
Ventricular tachycardia after experimental myocardial infarction: effects of adrenergic amines and increased aortic pressure.
    Texas reports on biology and medicine, 1965,Fall, Volume: 23, Issue:3

    Topics: Animals; Blood Pressure; Coronary Vessels; Dogs; Electrocardiography; Epinephrine; Heart Rate; Isopr

1965
Acute cardiac infarct like necrosis in high altitude adapted rats.
    Physiologia bohemoslovenica, 1965, Volume: 14, Issue:6

    Topics: Acclimatization; Altitude; Animals; Heart; Isoproterenol; Male; Myocardial Infarction; Myocardium; N

1965
[On treatment of rhythmic disorders in recent myocardial infarct].
    Deutsche medizinische Wochenschrift (1946), 1966, Nov-11, Volume: 91, Issue:45

    Topics: Aged; Atrial Fibrillation; Atrial Flutter; Electric Countershock; Electrocardiography; Female; Heart

1966
Cardio-pulmonary resuscitation. A report on two years' experience.
    Anaesthesia, 1966, Volume: 21, Issue:3

    Topics: Acidosis; Adolescent; Adult; Aged; Bicarbonates; Child; Child, Preschool; Electric Countershock; Hea

1966