isoproterenol has been researched along with Cardiotoxicity in 51 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, researchers recently investigated the potential cardioprotective effects of taraxerol utilizing an isoproterenol (ISO)-induced cardiotoxicity model among Sprague Dawley rats." | 8.31 | Effects of Taraxerol on Oxidative and Inflammatory Mediators in Isoproterenol-Induced Cardiotoxicity in an Animal Model. ( Alam, A; Alkholifi, FK; Aodah, AH; Devi, S; Foudah, AI; Yusufoglu, HS, 2023) |
| "The present study investigated the cardioprotective effects of activated platelet-rich plasma (PRP) on high dose isoproterenol (ISO) induced cardiotoxicity." | 8.12 | Platelet-rich plasma exhibits anti-inflammatory effect and attenuates cardiomyocyte damage by reducing NF-κB and enhancing VEGF expression in isoproterenol induced cardiotoxicity model. ( Singh, G; Srivastava, S; Yadav, S, 2022) |
| " The study aims to understand the effect of arbutin on isoproterenol (ISO)-induced cardiac hypertrophy in mice." | 7.96 | Arbutin Attenuates Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting TLR-4/NF-κB Pathway in Mice. ( Alavala, S; Jerald, MK; Mir, SM; Nalban, N; Sangaraju, R; Sistla, R, 2020) |
| " This study aimed to evaluate protective effect of ergosterol (ER) on isoproterenol (ISO)-induced myocardial cardiotoxicity." | 7.96 | Ergosterol Attenuates Isoproterenol-Induced Myocardial Cardiotoxicity. ( Dai, C; Gao, Y; Jin, L; Li, S; Song, J; Xie, Q, 2020) |
| "This study was designed to investigate efficacy of Narirutin rich fraction (NRF), obtained from grape fruit peel, in the treatment of isoproterenol induced myocardial infarction in rats." | 7.91 | Attenuation of isoproterenol-induced cardiotoxicity in rats by Narirutin rich fraction from grape fruit. ( Barve, K; Bhatt, LK; Shaikh, S, 2019) |
| "The present study was designed to investigate the protective effect of ferulic acid (FA) against isoproterenol (ISO)-induced cardiac toxicity in rats." | 7.88 | Cardioprotective role of FA against isoproterenol induced cardiac toxicity. ( Jain, PG; Mahajan, UB; Shinde, SD; Surana, SJ, 2018) |
| " The present study was directed to investigate the effect of ATV pre- and post-treatment in isoproterenol (ISO)-induced cardiotoxicity in rats." | 7.88 | Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation. ( Ahmed, LA; Attalla, DM; Khattab, MM; Zaki, HF, 2018) |
| " This study was performed to investigate the effects of syrigaldehyde (SYD), a phytochemical against isoproterenol (ISO) induced cardiotoxicity model." | 7.88 | Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats. ( Akhtar, K; Mateen, S; Moin, S; Mubeena Mariyath, PM; Naeem, SS; Rizvi, W; Shahzad, S, 2018) |
| "Rutin, likely due to its pro-oxidative effects, can exacerbate catecholamine cardiotoxicity depending on the dose used." | 7.85 | Intravenous rutin in rat exacerbates isoprenaline-induced cardiotoxicity likely due to intracellular oxidative stress. ( Filipský, T; Hašková, P; Holečková, M; Hrdina, R; Mladěnka, P; Nováková, L; Palicka, V; Pilařová, V; Říha, M; Semecký, V; Šimůnek, T; Vávrová, J, 2017) |
| "In this study, the ability of KMP to protect heart against isoproterenol (ISO) induced oxidative stress and myocardial infarction was evaluated." | 7.83 | Kampeferol protects against oxidative stress and apoptotic damage in experimental model of isoproterenol-induced cardiac toxicity in rats. ( Arya, DS; Bhatia, J; Gamad, N; Goyal, SN; Malhotra, RK; Malik, S; Suchal, K, 2016) |
| " The mechanism of SF preventing daunorubicin-induced cardiotoxicity in juvenile rats is relevant to inhabited cardiac Troponin I expression." | 7.81 | [Sodium ferulate protects against daunorubicin-induced cardiotoxicity in juvenile rats]. ( Fang, QJ; He, RL; Lian, JB; Wu, ZJ; Yu, J, 2015) |
| " Since the pathophysiology of ISO-cardiotoxicity is complex, the aim of this study was to elucidate the effect of oral quercetin pretreatment on myocardial ISO toxicity." | 7.80 | Oral administration of quercetin is unable to protect against isoproterenol cardiotoxicity. ( Filipský, T; Holečková, M; Hrdina, R; Mladěnka, P; Nováková, L; Palicka, V; Pilařová, V; Ríha, M; Semecký, V; Vávrová, J; Vopršalová, M, 2014) |
| "781) levels with EESA treated groups compared to toxic control." | 5.72 | Protective Effects of Sauropus Androgynus Leaf Extract against Isoproterenol Induced Cardiotoxicity. ( A, SB; Ajmeer, R; C, R; Jain, V; K, N; Kumar, H; S, P, 2022) |
| "Isoproterenol (ISO) is a non-selective β-adrenergic agonist." | 5.51 | The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity. ( Czegledi, A; Gyongyosi, A; Lekli, I; Tosaki, A; Zilinyi, R, 2019) |
| " However, researchers recently investigated the potential cardioprotective effects of taraxerol utilizing an isoproterenol (ISO)-induced cardiotoxicity model among Sprague Dawley rats." | 4.31 | Effects of Taraxerol on Oxidative and Inflammatory Mediators in Isoproterenol-Induced Cardiotoxicity in an Animal Model. ( Alam, A; Alkholifi, FK; Aodah, AH; Devi, S; Foudah, AI; Yusufoglu, HS, 2023) |
| " After that, the use of the chemical compound was tested in the treatment of pregnant mice previously subjected to isoproterenol (fetal hypertrophy model) on the fifth day post coitus." | 4.31 | The sodium borate relieves the hypertrophic damage induced during pregnancy, it improves contractibility, reduces oxidative stress and stimulates cell proliferation. ( Contreras-Ramos, A; Cruz-Hernández, M; Díaz-Rosas, G; López-Torres, A; Ortega-Camarillo, C; Pedraza-Galeana, A, 2023) |
| "The present study investigated the cardioprotective effects of activated platelet-rich plasma (PRP) on high dose isoproterenol (ISO) induced cardiotoxicity." | 4.12 | Platelet-rich plasma exhibits anti-inflammatory effect and attenuates cardiomyocyte damage by reducing NF-κB and enhancing VEGF expression in isoproterenol induced cardiotoxicity model. ( Singh, G; Srivastava, S; Yadav, S, 2022) |
| " This study was conducted to assess the cardioprotective action of TPN against isoproterenol (ISO)-induced cardiotoxicity." | 4.12 | Alpha-terpineol prevents myocardial damage against isoproterenol-MI induced in Wistar-Kyoto rats: new possible to promote cardiovascular integrity. ( Bernardino, AC; de Oliveira, KRV; Machado, MLDP; Oliveira, AP; Paulino, ET; Quintans-Júnior, LJ; Ribeiro, ÊAN; Rodrigues, AKBF, 2022) |
| " Doxorubicin (DOX) and Isoproterenol (ISO) induced cardiotoxicity in wistar albino rats." | 3.96 | Investigation on protective effect of Terminalia bellirica (Roxb.) against drugs induced cardiotoxicity in wistar albino rats. ( Chaudhary, R; Kumar S, S; Kumar, N; Kumar, P; Singh, L; Singh, R; Verma, R, 2020) |
| " This study aimed to evaluate protective effect of ergosterol (ER) on isoproterenol (ISO)-induced myocardial cardiotoxicity." | 3.96 | Ergosterol Attenuates Isoproterenol-Induced Myocardial Cardiotoxicity. ( Dai, C; Gao, Y; Jin, L; Li, S; Song, J; Xie, Q, 2020) |
| " The study aims to understand the effect of arbutin on isoproterenol (ISO)-induced cardiac hypertrophy in mice." | 3.96 | Arbutin Attenuates Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting TLR-4/NF-κB Pathway in Mice. ( Alavala, S; Jerald, MK; Mir, SM; Nalban, N; Sangaraju, R; Sistla, R, 2020) |
| "This study was designed to investigate efficacy of Narirutin rich fraction (NRF), obtained from grape fruit peel, in the treatment of isoproterenol induced myocardial infarction in rats." | 3.91 | Attenuation of isoproterenol-induced cardiotoxicity in rats by Narirutin rich fraction from grape fruit. ( Barve, K; Bhatt, LK; Shaikh, S, 2019) |
| " This study was performed to investigate the effects of syrigaldehyde (SYD), a phytochemical against isoproterenol (ISO) induced cardiotoxicity model." | 3.88 | Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats. ( Akhtar, K; Mateen, S; Moin, S; Mubeena Mariyath, PM; Naeem, SS; Rizvi, W; Shahzad, S, 2018) |
| "The present study was designed to investigate the protective effect of ferulic acid (FA) against isoproterenol (ISO)-induced cardiac toxicity in rats." | 3.88 | Cardioprotective role of FA against isoproterenol induced cardiac toxicity. ( Jain, PG; Mahajan, UB; Shinde, SD; Surana, SJ, 2018) |
| "In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed." | 3.88 | Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication. ( Chen, Y; Cheng, Y; Chu, L; Duan, R; Li, H; Li, J; Xia, D; Yuan, J; Zhang, J; Zhang, Y; Zhao, S; Zhao, X, 2018) |
| " Isoproterenol (ISO)-induced cardiotoxicity challenged mice were treated with NY for 28 days at two doses (0." | 3.88 | Nanoyttria attenuates isoproterenol-induced cardiac injury. ( Godugu, C; Khurana, A; Kumari, P, 2018) |
| " The present study was directed to investigate the effect of ATV pre- and post-treatment in isoproterenol (ISO)-induced cardiotoxicity in rats." | 3.88 | Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation. ( Ahmed, LA; Attalla, DM; Khattab, MM; Zaki, HF, 2018) |
| "Rutin, likely due to its pro-oxidative effects, can exacerbate catecholamine cardiotoxicity depending on the dose used." | 3.85 | Intravenous rutin in rat exacerbates isoprenaline-induced cardiotoxicity likely due to intracellular oxidative stress. ( Filipský, T; Hašková, P; Holečková, M; Hrdina, R; Mladěnka, P; Nováková, L; Palicka, V; Pilařová, V; Říha, M; Semecký, V; Šimůnek, T; Vávrová, J, 2017) |
| "In this study, the ability of KMP to protect heart against isoproterenol (ISO) induced oxidative stress and myocardial infarction was evaluated." | 3.83 | Kampeferol protects against oxidative stress and apoptotic damage in experimental model of isoproterenol-induced cardiac toxicity in rats. ( Arya, DS; Bhatia, J; Gamad, N; Goyal, SN; Malhotra, RK; Malik, S; Suchal, K, 2016) |
| " The mechanism of SF preventing daunorubicin-induced cardiotoxicity in juvenile rats is relevant to inhabited cardiac Troponin I expression." | 3.81 | [Sodium ferulate protects against daunorubicin-induced cardiotoxicity in juvenile rats]. ( Fang, QJ; He, RL; Lian, JB; Wu, ZJ; Yu, J, 2015) |
| " Since the pathophysiology of ISO-cardiotoxicity is complex, the aim of this study was to elucidate the effect of oral quercetin pretreatment on myocardial ISO toxicity." | 3.80 | Oral administration of quercetin is unable to protect against isoproterenol cardiotoxicity. ( Filipský, T; Holečková, M; Hrdina, R; Mladěnka, P; Nováková, L; Palicka, V; Pilařová, V; Ríha, M; Semecký, V; Vávrová, J; Vopršalová, M, 2014) |
| "781) levels with EESA treated groups compared to toxic control." | 1.72 | Protective Effects of Sauropus Androgynus Leaf Extract against Isoproterenol Induced Cardiotoxicity. ( A, SB; Ajmeer, R; C, R; Jain, V; K, N; Kumar, H; S, P, 2022) |
| "Isoproterenol (ISO) is a non-selective β-adrenergic agonist." | 1.51 | The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity. ( Czegledi, A; Gyongyosi, A; Lekli, I; Tosaki, A; Zilinyi, R, 2019) |
| " Wistar rats were dosed once with either isoproterenol (1." | 1.48 | miR-21-5p as a potential biomarker of inflammatory infiltration in the heart upon acute drug-induced cardiac injury in rats. ( De Ron, P; Fleming, A; Fleurance, R; Gryshkova, V; McGhan, P; Nogueira da Costa, A; Valentin, JP, 2018) |
| "Diosmin pretreatment showed significant preventive effects on all the biochemical parameters, and the structure of mitochondria was evaluated." | 1.48 | Diosmin Prevents Isoproterenol-Induced Heart Mitochondrial Oxidative Stress in Rats. ( John, B; Sharmila Queenthy, S; Stanely Mainzen Prince, P, 2018) |
| "Cardiotoxicity is one of the most serious side effects of new drugs." | 1.46 | Screening, verification, and analysis of biomarkers for drug-induced cardiac toxicity in vitro based on RTCA coupled with PCR Array technology. ( Cheng, XL; Ren, YR; Xu, MX; Yin, QS; Zhang, L; Zhang, YJ; Zhu, CY; Zhuang, PW, 2017) |
| " Plasma miR-208 was consistently increased through 24 h after dosing in rats administered with isoproterenol, whereas plasma concentrations of cardiac troponin (cTn) showed transient elevation." | 1.42 | Plasma miR-208 as a useful biomarker for drug-induced cardiotoxicity in rats. ( Kondo, C; Morikawa, Y; Nishimura, Y; Tonomura, Y; Torii, M; Uehara, T; Yamate, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.88) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 26 (50.98) | 24.3611 |
| 2020's | 22 (43.14) | 2.80 |
| Authors | Studies |
|---|---|
| Cinar, I | 1 |
| Yayla, M | 1 |
| Tavaci, T | 1 |
| Toktay, E | 1 |
| Ugan, RA | 1 |
| Bayram, P | 1 |
| Halici, H | 1 |
| Paulino, ET | 1 |
| Rodrigues, AKBF | 1 |
| Machado, MLDP | 1 |
| de Oliveira, KRV | 1 |
| Bernardino, AC | 1 |
| Quintans-Júnior, LJ | 1 |
| Oliveira, AP | 1 |
| Ribeiro, ÊAN | 1 |
| Yadav, S | 2 |
| Srivastava, S | 2 |
| Singh, G | 2 |
| S, P | 1 |
| Kumar, H | 1 |
| C, R | 1 |
| A, SB | 1 |
| K, N | 1 |
| Ajmeer, R | 1 |
| Jain, V | 1 |
| Aodah, AH | 1 |
| Devi, S | 1 |
| Alkholifi, FK | 1 |
| Yusufoglu, HS | 1 |
| Foudah, AI | 1 |
| Alam, A | 1 |
| Chen, Y | 2 |
| Guo, X | 1 |
| Zeng, Y | 1 |
| Mo, X | 1 |
| Hong, S | 1 |
| He, H | 1 |
| Li, J | 2 |
| Steinmetz, R | 1 |
| Liu, Q | 1 |
| Díaz-Rosas, G | 1 |
| Cruz-Hernández, M | 1 |
| Ortega-Camarillo, C | 1 |
| Pedraza-Galeana, A | 1 |
| López-Torres, A | 1 |
| Contreras-Ramos, A | 1 |
| Nalban, N | 1 |
| Sangaraju, R | 1 |
| Alavala, S | 1 |
| Mir, SM | 1 |
| Jerald, MK | 1 |
| Sistla, R | 1 |
| Boshra, SA | 1 |
| Sharma, S | 1 |
| Khan, V | 1 |
| Dhyani, N | 1 |
| Najmi, AK | 1 |
| Haque, SE | 1 |
| S, M | 1 |
| Shaik, AH | 1 |
| E, MP | 1 |
| Al Omar, SY | 1 |
| Mohammad, A | 1 |
| Kodidhela, LD | 1 |
| Ryu, B | 1 |
| Choi, SW | 1 |
| Lee, SG | 1 |
| Jeong, YH | 1 |
| Kim, U | 1 |
| Kim, J | 1 |
| Jung, CR | 1 |
| Chung, HM | 1 |
| Park, JH | 1 |
| Kim, CY | 1 |
| Xie, Q | 1 |
| Li, S | 1 |
| Gao, Y | 1 |
| Jin, L | 1 |
| Dai, C | 1 |
| Song, J | 1 |
| Arai, K | 1 |
| Murata, D | 1 |
| Takao, S | 1 |
| Nakamura, A | 1 |
| Itoh, M | 1 |
| Kitsuka, T | 1 |
| Nakayama, K | 1 |
| Chaudhary, R | 1 |
| Singh, R | 1 |
| Verma, R | 1 |
| Kumar, P | 1 |
| Kumar, N | 1 |
| Singh, L | 1 |
| Kumar S, S | 1 |
| Zhang, E | 1 |
| Yang, H | 1 |
| Li, M | 1 |
| Ding, M | 1 |
| Pavithra, K | 1 |
| Sathibabu Uddandrao, VV | 1 |
| Chandrasekaran, P | 1 |
| Brahmanaidu, P | 1 |
| Sengottuvelu, S | 1 |
| Vadivukkarasi, S | 1 |
| Saravanan, G | 1 |
| Rababa'h, AM | 1 |
| Alzoubi, MA | 1 |
| Ahmad, S | 1 |
| Mahmood, T | 2 |
| Kumar, R | 1 |
| Bagga, P | 1 |
| Ahsan, F | 1 |
| Shamim, A | 1 |
| Ansari, A | 1 |
| Shariq, M | 1 |
| Bagang, N | 1 |
| Rajput, S | 1 |
| Sharma, D | 1 |
| Dahiya, A | 1 |
| Bhardwaj, L | 1 |
| Deshmukh, K | 1 |
| Joshi, JC | 1 |
| Feng, K | 1 |
| Liu, Y | 1 |
| Sun, J | 1 |
| Zhao, C | 1 |
| Duan, Y | 1 |
| Wang, W | 1 |
| Yan, K | 1 |
| Yan, X | 1 |
| Sun, H | 1 |
| Hu, Y | 1 |
| Han, J | 1 |
| Sharmila Queenthy, S | 1 |
| Stanely Mainzen Prince, P | 1 |
| John, B | 1 |
| Sözmen, M | 3 |
| Devrim, AK | 3 |
| Kabak, YB | 3 |
| Devrim, T | 3 |
| Sudagidan, M | 2 |
| Cinar, M | 1 |
| Gryshkova, V | 1 |
| Fleming, A | 1 |
| McGhan, P | 1 |
| De Ron, P | 2 |
| Fleurance, R | 1 |
| Valentin, JP | 2 |
| Nogueira da Costa, A | 2 |
| Attalla, DM | 1 |
| Ahmed, LA | 1 |
| Zaki, HF | 1 |
| Khattab, MM | 1 |
| Khwaja, S | 1 |
| Siddiqui, HH | 1 |
| Jain, PG | 1 |
| Mahajan, UB | 1 |
| Shinde, SD | 1 |
| Surana, SJ | 1 |
| Shahzad, S | 2 |
| Mateen, S | 2 |
| Mubeena Mariyath, PM | 1 |
| Naeem, SS | 2 |
| Akhtar, K | 2 |
| Rizvi, W | 2 |
| Moin, S | 2 |
| Duan, R | 1 |
| Zhang, Y | 2 |
| Zhao, X | 1 |
| Cheng, Y | 1 |
| Yuan, J | 1 |
| Li, H | 1 |
| Zhang, J | 1 |
| Chu, L | 1 |
| Xia, D | 1 |
| Zhao, S | 1 |
| Godugu, C | 1 |
| Kumari, P | 1 |
| Khurana, A | 1 |
| Shaikh, S | 1 |
| Bhatt, LK | 1 |
| Barve, K | 1 |
| Singh, PK | 1 |
| Gari, M | 1 |
| Choudhury, S | 1 |
| Shukla, A | 1 |
| Gangwar, N | 1 |
| Garg, SK | 1 |
| Gyongyosi, A | 1 |
| Zilinyi, R | 1 |
| Czegledi, A | 1 |
| Tosaki, A | 2 |
| Lekli, I | 1 |
| Asaikumar, L | 1 |
| Vennila, L | 1 |
| Akila, P | 1 |
| Sivasangari, S | 1 |
| Kanimozhi, K | 1 |
| Premalatha, V | 1 |
| Sindhu, G | 1 |
| Adaramoye, OA | 1 |
| Lawal, SO | 1 |
| Ríha, M | 2 |
| Vopršalová, M | 1 |
| Pilařová, V | 2 |
| Semecký, V | 2 |
| Holečková, M | 2 |
| Vávrová, J | 2 |
| Palicka, V | 2 |
| Filipský, T | 2 |
| Hrdina, R | 2 |
| Nováková, L | 2 |
| Mladěnka, P | 2 |
| Nishimura, Y | 1 |
| Kondo, C | 1 |
| Morikawa, Y | 1 |
| Tonomura, Y | 1 |
| Torii, M | 1 |
| Yamate, J | 1 |
| Uehara, T | 1 |
| Li, Y | 1 |
| Ju, L | 1 |
| Hou, Z | 1 |
| Deng, H | 1 |
| Zhang, Z | 1 |
| Wang, L | 1 |
| Yang, Z | 1 |
| Yin, J | 1 |
| Lian, JB | 1 |
| Wu, ZJ | 1 |
| Fang, QJ | 1 |
| Yu, J | 1 |
| He, RL | 1 |
| Glineur, SF | 1 |
| Hanon, E | 1 |
| Dremier, S | 1 |
| Kim, JY | 1 |
| Choi, YS | 1 |
| Lee, BK | 1 |
| Lee, DW | 1 |
| Hašková, P | 1 |
| Šimůnek, T | 1 |
| Suchal, K | 1 |
| Malik, S | 1 |
| Gamad, N | 1 |
| Malhotra, RK | 1 |
| Goyal, SN | 1 |
| Bhatia, J | 1 |
| Arya, DS | 1 |
| Zhang, L | 1 |
| Xu, MX | 1 |
| Yin, QS | 1 |
| Zhu, CY | 1 |
| Cheng, XL | 1 |
| Ren, YR | 1 |
| Zhuang, PW | 1 |
| Zhang, YJ | 1 |
| Zhao, Q | 1 |
| Wang, X | 1 |
| Wang, S | 1 |
| Song, Z | 1 |
| Wang, J | 1 |
| Ma, J | 1 |
| BALAZS, T | 2 |
| SAHASRABUDHE, MR | 1 |
| GRICE, HC | 2 |
| BECKER, DJ | 1 |
| NONKIN, PM | 1 |
| BENNET, LD | 1 |
| KIMBALL, SG | 1 |
| STERNBERG, MS | 1 |
| WASSERMAN, F | 1 |
| MURPHY, JB | 1 |
51 other studies available for isoproterenol and Cardiotoxicity
| Article | Year |
|---|---|
In Vivo and In Vitro Cardioprotective Effect of Gossypin Against Isoproterenol-Induced Myocardial Infarction Injury.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cardiotox | 2022 |
Alpha-terpineol prevents myocardial damage against isoproterenol-MI induced in Wistar-Kyoto rats: new possible to promote cardiovascular integrity.
Topics: Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Cardiotoxicity; Cardiovascular Diseases; Cycl | 2022 |
Platelet-rich plasma exhibits anti-inflammatory effect and attenuates cardiomyocyte damage by reducing NF-κB and enhancing VEGF expression in isoproterenol induced cardiotoxicity model.
Topics: Animals; Anti-Inflammatory Agents; Cardiotoxicity; Isoproterenol; Myocardium; Myocytes, Cardiac; NF- | 2022 |
Protective Effects of Sauropus Androgynus Leaf Extract against Isoproterenol Induced Cardiotoxicity.
Topics: Animals; Antioxidants; Cardiotoxicity; Isoproterenol; Myocardium; Plant Extracts; Rats | 2022 |
Effects of Taraxerol on Oxidative and Inflammatory Mediators in Isoproterenol-Induced Cardiotoxicity in an Animal Model.
Topics: Animals; Antioxidants; Cardiotoxicity; Disease Models, Animal; Inflammation Mediators; Isoproterenol | 2023 |
Ferroptosis contributes to catecholamine-induced cardiotoxicity and pathological remodeling.
Topics: Cardiotoxicity; Catecholamines; Ferroptosis; Heart Failure; Humans; Iron; Isoproterenol; Reactive Ox | 2023 |
The sodium borate relieves the hypertrophic damage induced during pregnancy, it improves contractibility, reduces oxidative stress and stimulates cell proliferation.
Topics: Animals; Cardiotoxicity; Cell Proliferation; Female; Glutathione; Hypertrophy; Isoproterenol; Mice; | 2023 |
Arbutin Attenuates Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting TLR-4/NF-κB Pathway in Mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arbutin; Atrial Natriuretic Factor; Cardiomegaly; C | 2020 |
Resveratrol Modulates miR-34a in Cardiotoxicity Induced by Isoproterenol.
Topics: Animals; Cardiotoxicity; Heart; Isoproterenol; Male; MicroRNAs; Myocardium; Random Allocation; Rats; | 2020 |
Icariin attenuates isoproterenol-induced cardiac toxicity in Wistar rats via modulating cGMP level and NF-κB signaling cascade.
Topics: Animals; Cardiotoxicity; Flavonoids; Heart; Isoproterenol; Models, Animal; Oxidative Stress; Rats; R | 2020 |
Combined cardio-protective ability of syringic acid and resveratrol against isoproterenol induced cardio-toxicity in rats via attenuating NF-kB and TNF-α pathways.
Topics: Animals; Cardiotonic Agents; Cardiotoxicity; Gallic Acid; Isoproterenol; Male; NF-kappa B; Rats; Rat | 2020 |
Development and evaluation of next-generation cardiotoxicity assay based on embryonic stem cell-derived cardiomyocytes.
Topics: Animals; Cardiotoxicity; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Doxorubicin; | 2020 |
Ergosterol Attenuates Isoproterenol-Induced Myocardial Cardiotoxicity.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cardiotoxicity; Cell Line; Disease | 2020 |
Drug response analysis for scaffold-free cardiac constructs fabricated using bio-3D printer.
Topics: Cardiotoxicity; Cell Survival; Doxorubicin; Drug Evaluation, Preclinical; Heterocyclic Compounds, 4 | 2020 |
Investigation on protective effect of Terminalia bellirica (Roxb.) against drugs induced cardiotoxicity in wistar albino rats.
Topics: Animals; Biomarkers; Cardiomyopathies; Cardiotoxicity; Disease Models, Animal; Doxorubicin; Fruit; I | 2020 |
A possible underlying mechanism behind the cardioprotective efficacy of tangeretin on isoproterenol triggered cardiotoxicity via modulating PI3K/Akt signaling pathway in a rat model.
Topics: Animals; Cardiotoxicity; Flavones; Isoproterenol; Male; Phosphatidylinositol 3-Kinases; Proto-Oncoge | 2020 |
Phenolic fraction extracted from Kedrostis foetidissima leaves ameliorated isoproterenol-induced cardiotoxicity in rats through restoration of cardiac antioxidant status.
Topics: Animals; Antioxidants; Cardiotoxicity; Cucurbitaceae; Isoproterenol; Plant Extracts; Plant Leaves; R | 2020 |
Origanum majorana L. Extract Protects Against Isoproterenol-Induced Cardiotoxicity in Rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cardiotoxicity; Disease Models, Animal; | 2021 |
Comparative evaluation of cardioprotective activity of
Topics: Animals; Antioxidants; Cardiotoxicity; Isoproterenol; Lipid Peroxidation; Malus; Myocardium; Oxidati | 2021 |
Evolution of β-catenin-independent Wnt-GSK3-mTOR signalling in regulation of energy metabolism in isoproterenol-induced cardiotoxicity model.
Topics: Adrenergic beta-Agonists; Animals; beta Catenin; Cardiotoxicity; Disease Models, Animal; Energy Meta | 2021 |
Compound Danshen Dripping Pill inhibits doxorubicin or isoproterenol-induced cardiotoxicity.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Camphanes; Cardiotoxicity; Cell Line; Di | 2021 |
Diosmin Prevents Isoproterenol-Induced Heart Mitochondrial Oxidative Stress in Rats.
Topics: Animals; Antioxidants; Biomarkers; Calcium Signaling; Cardiotoxicity; Cytoprotection; Diosmin; Disea | 2018 |
The Effects of Periostin in a Rat Model of Isoproterenol: Mediated Cardiotoxicity.
Topics: Animals; Apoptosis; Cardiotoxicity; Cell Adhesion Molecules; Cell Proliferation; Cytoprotection; Dis | 2018 |
Periostin normalizes levels of cardiac markers in rats with experimental isoproterenol cardiotoxicity.
Topics: Alanine Transaminase; Animals; Antioxidants; Cardiotoxicity; Catalase; Cell Adhesion Molecules; Isop | 2017 |
miR-21-5p as a potential biomarker of inflammatory infiltration in the heart upon acute drug-induced cardiac injury in rats.
Topics: Allylamine; Animals; Cardiotoxicity; Disease Models, Animal; Gene Expression Profiling; Gene Express | 2018 |
Paradoxical effects of atorvastatin in isoproterenol-induced cardiotoxicity in rats: Role of oxidative stress and inflammation.
Topics: Animals; Antioxidants; Atorvastatin; Biomarkers; Cardiotonic Agents; Cardiotoxicity; Heart; Inflamma | 2018 |
Effect of ethanolic extract of Cyperus rotundus L. against isoprenaline induced cardiotoxicity.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarker | 2016 |
Cardioprotective role of FA against isoproterenol induced cardiac toxicity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Cardiotonic Agents; Cardioto | 2018 |
Protective effect of syringaldehyde on biomolecular oxidation, inflammation and histopathological alterations in isoproterenol induced cardiotoxicity in rats.
Topics: Adenosine Triphosphatases; Animals; Antioxidants; Benzaldehydes; Biomarkers; Cardiotoxicity; Erythro | 2018 |
Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication.
Topics: Anesthesia; Animals; Blood Pressure; Bupivacaine; Cardiotoxicity; Chloral Hydrate; Disease Models, A | 2018 |
Periostin alters transcriptional profile in a rat model of isoproterenol-induced cardiotoxicity.
Topics: Animals; Cardiotoxicity; Cell Adhesion Molecules; Disease Models, Animal; Isoproterenol; Male; Rats, | 2019 |
Nanoyttria attenuates isoproterenol-induced cardiac injury.
Topics: Animals; Cardiotoxicity; Cytokines; Gene Expression Regulation; Heart; Heart Injuries; Hydroxyprolin | 2018 |
Attenuation of isoproterenol-induced cardiotoxicity in rats by Narirutin rich fraction from grape fruit.
Topics: Adrenergic beta-Agonists; Animals; Cardiotoxicity; Citrus paradisi; Disaccharides; Flavanones; Heart | 2019 |
Syringic acid protects from isoproterenol induced cardiotoxicity in rats.
Topics: Adenosine Triphosphatases; Animals; Biomarkers; Biphenyl Compounds; Body Weight; Cardiotoxicity; Cyt | 2019 |
Oleic Acid Prevents Isoprenaline-Induced Cardiac Injury: Effects on Cellular Oxidative Stress, Inflammation and Histopathological Alterations.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cardiotoxicity; Disease Models, Animal; Inflammatio | 2020 |
The Role of Autophagy and Death Pathways in Dose-dependent Isoproterenolinduced Cardiotoxicity.
Topics: Animals; Apoptosis; Autophagy; Cardiotoxicity; Heart; Isoproterenol; Male; Myocardium; Rats; Rats, S | 2019 |
Preventive effect of nerolidol on isoproterenol induced myocardial damage in Wistar rats: Evidences from biochemical and histopathological studies.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardiotonic Agents; Cardiotoxicity; Cata | 2019 |
Kolaviron, a biflavonoid fraction from Garcinia kola, protects against isoproterenol-induced injury by mitigating cardiac dysfunction and oxidative stress in rats.
Topics: Animals; Antioxidants; Cardiotonic Agents; Cardiotoxicity; Dose-Response Relationship, Drug; Flavono | 2015 |
Oral administration of quercetin is unable to protect against isoproterenol cardiotoxicity.
Topics: Administration, Oral; Animals; Aorta, Thoracic; Cardiotoxicity; Hemodynamics; Isoproterenol; Male; M | 2014 |
Plasma miR-208 as a useful biomarker for drug-induced cardiotoxicity in rats.
Topics: Animals; Biomarkers; Cardiotoxicity; Doxorubicin; Heart; Isoproterenol; Male; MicroRNAs; Muscle, Ske | 2015 |
Screening, verification, and optimization of biomarkers for early prediction of cardiotoxicity based on metabolomics.
Topics: Animals; Biomarkers; Cardiotoxicity; Doxorubicin; Fluorouracil; Heart; Isoproterenol; Male; Metabolo | 2015 |
[Sodium ferulate protects against daunorubicin-induced cardiotoxicity in juvenile rats].
Topics: Animals; Blood Pressure; Cardiotoxicity; Coumaric Acids; Daunorubicin; Heart; Heart Rate; Isoprotere | 2015 |
Paving the Route to Plasma miR-208a-3p as an Acute Cardiac Injury Biomarker: Preclinical Rat Data Supports Its Use in Drug Safety Assessment.
Topics: Acute Disease; Allylamine; Animals; Biomarkers; Cardiotoxicity; Isoproterenol; Male; MicroRNAs; Rats | 2016 |
Surface-patterned SU-8 cantilever arrays for preliminary screening of cardiac toxicity.
Topics: Animals; Astemizole; Biosensing Techniques; Cardiotoxicity; Cells, Cultured; Drug-Related Side Effec | 2016 |
Intravenous rutin in rat exacerbates isoprenaline-induced cardiotoxicity likely due to intracellular oxidative stress.
Topics: Animals; Cardiotoxicity; Cell Line; Dinoprost; Dose-Response Relationship, Drug; Electrocardiography | 2017 |
Kampeferol protects against oxidative stress and apoptotic damage in experimental model of isoproterenol-induced cardiac toxicity in rats.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cardiotoxicity; Catalase; Glutathione; Heart; Interleu | 2016 |
Screening, verification, and analysis of biomarkers for drug-induced cardiac toxicity in vitro based on RTCA coupled with PCR Array technology.
Topics: Animals; Animals, Newborn; Cardiotoxicity; Cells, Cultured; Dose-Response Relationship, Drug; Doxoru | 2017 |
Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes.
Topics: Cardiotoxicity; Cell Differentiation; Drug Discovery; Haloperidol; Human Embryonic Stem Cells; Human | 2017 |
The influence of excess body fat on the cardiotoxicity of isoproterenol in rats.
Topics: Adipose Tissue; Animals; Cardiotoxicity; Heart; Isoproterenol; Rats; Sympathomimetics | 1962 |
Effect of isoproterenol in digitalis cardiotoxicity.
Topics: Arrhythmias, Cardiac; Cardiotoxicity; Cardiovascular Diseases; Digitalis; Heart Block; Humans; Isopr | 1962 |
The influence of environmental changes on the cardiotoxicity of isoprenaline in rats.
Topics: Animals; Cardiotoxicity; Cold Temperature; Environment; Heart; Isoproterenol; Rats; Stress, Physiolo | 1962 |