isoproterenol has been researched along with Cardiac Output, Low in 45 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In eight anesthetized ventilated goats, the hemodynamic effect of isoproterenol (ISU), dopamine (DOP), norepinephrine (NE), nitroglycerin (NTG), and Ringer's lactate (RL) infusion was evaluated after inducing acute pulmonary hypertension (PHN) to decrease cardiac output." | 3.67 | Treatment of low cardiac output complicating acute pulmonary hypertension in normovolemic goats. ( Mathru, M; Shirakawa, Y; Smith, RA; Sugiura, A; Venus, B, 1986) |
| " Slope of log dose-response for heart rate and QS2i was similar with dobutamine and with isoprenaline, corresponding to stimulation of the same type of beta-adrenergic receptors (beta 1-subtype)." | 2.68 | Evaluation of cardiac beta 1-adrenergic sensitivity with dobutamine in healthy volunteers. ( Chalon, S; Diquet, B; Lechat, P; Pousset, F; Thomaré, P, 1995) |
| "Three stages of cardiac hypertrophy due to volume overload were recognized during the 16-wk period." | 1.32 | Characterization of cardiac hypertrophy and heart failure due to volume overload in the rat. ( Dhalla, NS; Liu, S; Ren, B; Sentex, E; Tappia, PS; Wang, X, 2003) |
| "The relation between cardiac hypertrophy, shunt size, myocardial contractility, capillary density, adrenergic responsiveness, and neurohumoral stimulation was evaluated in dogs with compensated and decompensated cardiac hypertrophy caused by an infrarenal aorto-caval shunt." | 1.28 | Functional and morphological characteristics of compensated and decompensated cardiac hypertrophy in dogs with chronic infrarenal aorto-caval fistulas. ( Juneau, C; Legault, F; Rakusan, K; Rose, C; Rouleau, JL, 1990) |
| " In concordance with this decreased receptor density and increased affinity, the maximal contractile response of right ventricular trabeculae from failing right ventricles was decreased by 61%, and the dose-response curve to VIP was left-shifted approximately threefold." | 1.28 | Vasoactive intestinal peptide receptor in failing human ventricular myocardium exhibits increased affinity and decreased density. ( Anderson, FL; Bristow, MR; Hershberger, RE, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (20.00) | 18.7374 |
| 1990's | 24 (53.33) | 18.2507 |
| 2000's | 12 (26.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, XP | 1 |
| Tada, H | 1 |
| Wang, Z | 1 |
| Hintze, TH | 1 |
| Wang, X | 1 |
| Ren, B | 1 |
| Liu, S | 1 |
| Sentex, E | 1 |
| Tappia, PS | 1 |
| Dhalla, NS | 1 |
| Hodgson, DM | 1 |
| Zingman, LV | 1 |
| Kane, GC | 1 |
| Perez-Terzic, C | 1 |
| Bienengraeber, M | 1 |
| Ozcan, C | 1 |
| Gumina, RJ | 1 |
| Pucar, D | 1 |
| O'Coclain, F | 1 |
| Mann, DL | 1 |
| Alekseev, AE | 1 |
| Terzic, A | 1 |
| ROE, BB | 1 |
| BRUNS, DL | 1 |
| Brixius, K | 2 |
| Wollmer, A | 1 |
| Bölck, B | 1 |
| Mehlhorn, U | 1 |
| Schwinger, RH | 3 |
| Ziolo, MT | 1 |
| Maier, LS | 1 |
| Piacentino, V | 1 |
| Bossuyt, J | 1 |
| Houser, SR | 2 |
| Bers, DM | 1 |
| Krenz, M | 1 |
| Robbins, J | 1 |
| Moalem, J | 1 |
| Weiss, HR | 1 |
| Davidov, T | 1 |
| Rodriguez, R | 1 |
| Molino, B | 1 |
| Lazar, MJ | 1 |
| Scholz, PM | 1 |
| Giuberti, K | 1 |
| Pereira, RB | 1 |
| Bianchi, PR | 1 |
| Paigel, AS | 1 |
| Vassallo, DV | 1 |
| Stefanon, I | 1 |
| Krishnamurthy, P | 1 |
| Subramanian, V | 1 |
| Singh, M | 1 |
| Singh, K | 1 |
| Wei, SK | 1 |
| McCurley, JM | 1 |
| Hanlon, SU | 1 |
| Haigney, MC | 1 |
| Bourdarias, JP | 1 |
| Dubourg, O | 1 |
| Gueret, P | 1 |
| Ferrier, A | 1 |
| Bardet, J | 1 |
| Parisi, F | 1 |
| Corno, A | 1 |
| La Vigna, G | 1 |
| Catena, G | 1 |
| Marcelletti, C | 1 |
| Montero Benzo, R | 1 |
| Vicente Sánchez, JL | 1 |
| Alepuz Ferrer, R | 1 |
| Vatner, DE | 2 |
| Sato, N | 2 |
| Kiuchi, K | 2 |
| Shannon, RP | 2 |
| Vatner, SF | 2 |
| Klabunde, RE | 1 |
| Coston, AF | 1 |
| Pousset, F | 1 |
| Chalon, S | 1 |
| Thomaré, P | 1 |
| Diquet, B | 1 |
| Lechat, P | 1 |
| Morgan, K | 1 |
| Porsa, E | 1 |
| Freeman, GL | 1 |
| Herlihy, JT | 1 |
| Böhm, M | 2 |
| Müller-Ehmsen, J | 2 |
| Uhlmann, R | 1 |
| Schmidt, U | 1 |
| Stäblein, A | 1 |
| Uberfuhr, P | 1 |
| Kreuzer, E | 1 |
| Reichart, B | 1 |
| Eissner, HJ | 1 |
| Ungerer, M | 1 |
| Elce, JS | 1 |
| Erdmann, E | 1 |
| Lohse, MJ | 1 |
| Jaggers, J | 1 |
| Fullerton, DA | 1 |
| Campbell, DN | 1 |
| Andrea, B | 1 |
| Jones, SD | 1 |
| Brown, JM | 1 |
| Wolfel, EE | 1 |
| Lindenfeld, J | 1 |
| Grover, FL | 1 |
| Bristow, MR | 2 |
| Xiong, L | 1 |
| Bouanani, NE | 1 |
| Su, JB | 1 |
| Crozatier, B | 1 |
| Nasa, Y | 2 |
| Toyoshima, H | 2 |
| Ohaku, H | 1 |
| Hashizume, Y | 1 |
| Sanbe, A | 2 |
| Takeo, S | 2 |
| Todaka, K | 1 |
| Leibowitz, D | 1 |
| Homma, S | 1 |
| Fisher, PE | 1 |
| Derosa, C | 1 |
| Stennett, R | 1 |
| Packer, M | 1 |
| Burkhoff, D | 1 |
| Kohsaka, Y | 1 |
| Isayama, Y | 1 |
| Yamaguchi, F | 1 |
| Bellomo, R | 1 |
| Cole, L | 1 |
| Ronco, C | 1 |
| Davia, K | 1 |
| Harding, SE | 4 |
| Bavendiek, U | 1 |
| Münch, G | 1 |
| Zobel, C | 1 |
| Dipla, K | 1 |
| Mattiello, JA | 1 |
| Margulies, KB | 1 |
| Jeevanandam, V | 1 |
| Yoshida, H | 1 |
| Karmazyn, M | 1 |
| Sprung, J | 1 |
| Ogletree-Hughes, ML | 1 |
| Moravec, CS | 1 |
| Tamura, H | 1 |
| Ogawa, K | 1 |
| Atobe, M | 1 |
| Nagara, H | 1 |
| Matsumoto, M | 1 |
| Hiratsuka, H | 1 |
| Juneau, C | 2 |
| Calderone, A | 1 |
| Rouleau, JL | 2 |
| Brown, LA | 2 |
| Schneider, J | 1 |
| Beck, E | 1 |
| Heers, C | 1 |
| Conrad, C | 1 |
| de Chaffoy de Courcelles, D | 1 |
| Wilffert, B | 1 |
| Peters, T | 1 |
| De Broux, E | 1 |
| Lagacé, G | 1 |
| Chartrand, C | 1 |
| Jones, SM | 1 |
| O'Gara, P | 1 |
| Vescovo, G | 1 |
| Poole-Wilson, PA | 1 |
| Humphrey, SM | 1 |
| Legault, F | 1 |
| Rose, C | 1 |
| Rakusan, K | 1 |
| Balady, GJ | 1 |
| Jacobs, AK | 1 |
| Faxon, DP | 1 |
| Ryan, TJ | 1 |
| Hershberger, RE | 1 |
| Anderson, FL | 1 |
| Frey, MJ | 1 |
| Lanoce, V | 1 |
| Molinoff, PB | 1 |
| Wilson, JR | 1 |
| Stefenelli, T | 1 |
| Wu, ST | 1 |
| Parmley, WW | 1 |
| Mason, DT | 1 |
| Wikman-Coffelt, J | 1 |
| Mathru, M | 1 |
| Venus, B | 1 |
| Smith, RA | 1 |
| Shirakawa, Y | 1 |
| Sugiura, A | 1 |
2 reviews available for isoproterenol and Cardiac Output, Low
| Article | Year |
|---|---|
Inotropic agents in the treatment of cardiogenic shock.
Topics: Cardiac Output, Low; Cardiac Tamponade; Cardiotonic Agents; Catecholamines; Digitalis; Dobutamine; D | 1983 |
Hemodynamic support and the role of dopamine.
Topics: Acute Kidney Injury; Cardiac Output, Low; Cardiotonic Agents; Critical Care; Dobutamine; Dopamine; E | 1998 |
1 trial available for isoproterenol and Cardiac Output, Low
| Article | Year |
|---|---|
Evaluation of cardiac beta 1-adrenergic sensitivity with dobutamine in healthy volunteers.
Topics: Adult; Analysis of Variance; Cardiac Output, Low; Dobutamine; Dose-Response Relationship, Drug; Hear | 1995 |
42 other studies available for isoproterenol and Cardiac Output, Low
| Article | Year |
|---|---|
cAMP signal transduction, a potential compensatory pathway for coronary endothelial NO production after heart failure.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adrenomedullin; Animals; Bradykinin; Cardiac | 2002 |
Characterization of cardiac hypertrophy and heart failure due to volume overload in the rat.
Topics: Animals; Arteries; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Heart; Hemodynamics; Hyp | 2003 |
Cellular remodeling in heart failure disrupts K(ATP) channel-dependent stress tolerance.
Topics: Adenosine Triphosphate; Animals; Calcium; Cardiac Output, Low; Cardiotonic Agents; Creatine Kinase; | 2003 |
THE ARTIFICIAL CARDIAC PACEMAKER. INDICATIONS FOR IMPLANTATION.
Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atrioventricular Block; Bradycardia; Brugada Syndrome; | 1964 |
Ser16-, but not Thr17-phosphorylation of phospholamban influences frequency-dependent force generation in human myocardium.
Topics: Adrenergic beta-Agonists; Adult; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cardiac Out | 2003 |
Myocyte nitric oxide synthase 2 contributes to blunted beta-adrenergic response in failing human hearts by decreasing Ca2+ transients.
Topics: Adrenergic beta-Agonists; Calcium; Cardiac Output, Low; Cells, Cultured; Culture Techniques; Enzyme | 2004 |
Impact of beta-myosin heavy chain expression on cardiac function during stress.
Topics: Animals; Body Weight; Cardiac Output, Low; Cardiomegaly; Cardiotonic Agents; Chronic Disease; Dobuta | 2004 |
Heart failure reduces both the effects and interaction between cyclic GMP and cyclic AMP.
Topics: Animals; Cardiac Output, Low; Cardiotonic Agents; Coronary Circulation; Coronary Vessels; Cyclic AMP | 2006 |
Influence of ovariectomy in the right ventricular contractility in heart failure rats.
Topics: Animals; Cardiac Output, Low; Cardiotonic Agents; Estrogens; Female; Heart Ventricles; Isoproterenol | 2007 |
Beta1 integrins modulate beta-adrenergic receptor-stimulated cardiac myocyte apoptosis and myocardial remodeling.
Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Cardiac Output, Low; Echocardiography; Extracellular S | 2007 |
Gender differences in Na/Ca exchanger current and beta-adrenergic responsiveness in heart failure in pig myocytes.
Topics: Adrenergic beta-Agonists; Animals; Cardiac Output, Low; Cells, Cultured; Female; Furosemide; Heart V | 2007 |
[Use of sympathomimetic amines in the newborn infant: our experience].
Topics: Cardiac Output, Low; Child; Child, Preschool; Dopamine; Drug Therapy, Combination; Epinephrine; Hear | 1984 |
[Dobutamine in low cardiac output syndrome. Haemodynamic study (author's transl)].
Topics: Adult; Cardiac Output, Low; Catecholamines; Dobutamine; Dopamine; Female; Heart Failure; Hemodynamic | 1981 |
Decrease in myocardial ryanodine receptors and altered excitation-contraction coupling early in the development of heart failure.
Topics: Animals; Calcium Channels; Calcium Channels, L-Type; Cardiac Complexes, Premature; Cardiac Output, L | 1994 |
Nitric oxide synthase inhibition does not prevent cardiac depression in endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cardiac Output, Low; Dexamethasone; Guanidines; Heart | 1995 |
Depressed beta-adrenergic receptor- and endothelium-mediated vasodilation in conscious dogs with heart failure.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Cardiac Output, Low; Dogs; Endothelium, Vascular | 1993 |
Tachycardia heart failure alters rabbit aortic smooth muscle responsiveness to angiotensin II.
Topics: Angiotensin II; Animals; Aorta; Calcium; Cardiac Output, Low; Isoproterenol; Male; Muscle, Smooth; P | 1994 |
Effect of inotropic stimulation on the negative force-frequency relationship in the failing human heart.
Topics: Adult; Azetidines; Calcium; Cardiac Output, Low; Cardiotonic Agents; Cyclic AMP; Electric Stimulatio | 1993 |
Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.
Topics: Adult; Base Sequence; beta-Adrenergic Receptor Kinases; Binding, Competitive; Calcium; Cardiac Outpu | 1993 |
Cardiac allograft failure: successful use of biventricular assist device.
Topics: Adult; Cardiac Output, Low; Cardiotonic Agents; Combined Modality Therapy; Graft Rejection; Heart Tr | 1995 |
Propranolol therapy in experimental heart failure in rabbits improves cardiac response to catecholamines without beta-adrenoceptor up-regulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Cardiac Output, Low; Catecholamines | 1995 |
Impairment of cGMP- and cAMP-mediated vasorelaxations in rats with chronic heart failure.
Topics: Animals; Aorta, Thoracic; Cardiac Output, Low; Chronic Disease; Cyclic AMP; Cyclic GMP; Enzyme Inhib | 1996 |
Characterizing ventricular mechanics and energetics following repeated coronary microembolization.
Topics: Adrenergic beta-Agonists; Animals; Biomechanical Phenomena; Blood Pressure; Cardiac Output, Low; Chr | 1997 |
The effect of chronic treatment with trandolapril on cyclic AMP-and cyclic GMP-dependent relaxations in aortic segments of rats with chronic heart failure.
Topics: Acetylcholine; Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihype | 1998 |
Post-rest contraction amplitude in myocytes from failing human ventricle.
Topics: Analysis of Variance; Calcium; Cardiac Output, Low; Cardiotonic Agents; Colforsin; Digoxigenin; Drug | 1998 |
Effect of inotropic interventions on the force-frequency relation in the human heart.
Topics: Adrenergic beta-Agonists; Azetidines; Biomechanical Phenomena; Cardiac Output, Low; Cardiotonic Agen | 1998 |
The sarcoplasmic reticulum and the Na+/Ca2+ exchanger both contribute to the Ca2+ transient of failing human ventricular myocytes.
Topics: Action Potentials; Adrenergic beta-Agonists; Aged; Aged, 80 and over; Caffeine; Calcium; Calcium-Tra | 1999 |
Na(+)/H(+) exchange inhibition attenuates hypertrophy and heart failure in 1-wk postinfarction rat myocardium.
Topics: Adrenergic beta-Agonists; Animals; Cardiac Output, Low; Cardiomegaly; Guanidines; Hemodynamics; Isop | 2000 |
The effects of etomidate on the contractility of failing and nonfailing human heart muscle.
Topics: Adolescent; Adrenergic beta-Agonists; Aged; Anesthetics, Intravenous; Cardiac Output, Low; Coronary | 2000 |
[Hemodynamic comparison between isoproterenol and dopamine immediately after open heart surgery (author's transl)].
Topics: Adult; Blood Pressure; Cardiac Output, Low; Dopamine; Female; Heart Valve Prosthesis; Humans; Isopro | 1979 |
Myocardial beta-adrenergic and mechanical properties in pacing-induced heart failure in dogs.
Topics: Animals; Cardiac Output, Low; Cardiac Pacing, Artificial; Cyclic AMP; Dogs; Exercise Test; Heart; In | 1992 |
The effect of pertussis toxin on beta-adrenoceptor responses in isolated cardiac myocytes from noradrenaline-treated guinea-pigs and patients with cardiac failure.
Topics: Adult; Analysis of Variance; Animals; Calcium; Cardiac Output, Low; Child; Female; GTP-Binding Prote | 1992 |
Cardiac effects of R 79595 and its isomers (R 80122 and R 80123) in an acute heart failure model. A new class of cardiotonic agents with highly selective phosphodiesterase III inhibitory properties.
Topics: Animals; Cardiac Output; Cardiac Output, Low; Cardiotonic Agents; Female; Guinea Pigs; Heart; Heart | 1992 |
Efficacy of isoproterenol on the failing transplanted heart during early acute rejection.
Topics: Acute Disease; Animals; Cardiac Output, Low; Dogs; Graft Rejection; Heart Transplantation; Hemodynam | 1992 |
Reduced beta-agonist sensitivity in single atrial cells from failing human hearts.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cardiac Output, Low; Cardiotonic Agents; Cell Separation | 1990 |
The anti-adrenergic effect of adenosine and its blockade by pertussis toxin: a comparative study in myocytes isolated from guinea-pig, rat and failing human hearts.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Cardiac Output, Low; Guinea Pigs; Humans; In Vitro | 1990 |
Functional and morphological characteristics of compensated and decompensated cardiac hypertrophy in dogs with chronic infrarenal aorto-caval fistulas.
Topics: Adaptation, Physiological; Animals; Aorta; Arteriovenous Shunt, Surgical; Biomechanical Phenomena; C | 1990 |
Dynamic arm exercise during cardiac catheterization in the assessment of stenotic valvular disease.
Topics: Adult; Aged; Aortic Valve Stenosis; Arm; Blood Pressure; Cardiac Catheterization; Cardiac Output; Ca | 1990 |
Vasoactive intestinal peptide receptor in failing human ventricular myocardium exhibits increased affinity and decreased density.
Topics: Binding Sites; Cardiac Output, Low; Dose-Response Relationship, Drug; Heart Ventricles; Humans; In V | 1989 |
Skeletal muscle beta-receptors and isoproterenol-stimulated vasodilation in canine heart failure.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cardiac Output, Low; Data Interpretation, Statisti | 1989 |
Influence of positive inotropic agents on intracellular calcium transients. Part II. Cardiomyopathic hamster hearts.
Topics: Animals; Biomechanical Phenomena; Calcium; Cardiac Output, Low; Cardiomyopathies; Cardiotonic Agents | 1989 |
Treatment of low cardiac output complicating acute pulmonary hypertension in normovolemic goats.
Topics: Animals; Cardiac Output, Low; Dopamine; Goats; Hemodynamics; Hypertension, Pulmonary; Isoproterenol; | 1986 |