isoproterenol has been researched along with Cancer of Lung in 23 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Different pharmacologic drugs (isadrin, obsidan, phentolamine) changing adrenergic processes are shown to have different effect on the growth and development of lung metastases." | 3.67 | [Changes in the metastasis of experimental tumors and in the antimetastatic effect of cytostatics in their pharmacological action on adrenergic processes]. ( Balitskiĭ, KP; Riabukha, VN; Smelkova, MI; Veksler, IG, 1984) |
| "Treatment with isoproterenol (ISO), an analog of the stress signal epinephrine, increased the expression of HDAC6 protein and mRNA in H1299 lung cancer cells." | 1.43 | Isoproterenol increases histone deacetylase 6 expression and cell migration by inhibiting ERK signaling via PKA and Epac pathways in human lung cancer cells. ( Juhnn, YS; Lim, JA, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (30.43) | 18.7374 |
| 1990's | 7 (30.43) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, D | 1 |
| Zha, L | 1 |
| Liu, Y | 1 |
| Zhao, X | 1 |
| Xu, X | 1 |
| Liu, S | 1 |
| Ma, W | 1 |
| Zheng, J | 1 |
| Shi, M | 1 |
| Shan, M | 1 |
| Qin, J | 1 |
| Jin, F | 1 |
| Han, X | 1 |
| Guan, H | 1 |
| Li, X | 1 |
| Zhang, J | 1 |
| Zhang, H | 1 |
| Wang, Y | 1 |
| Herrero, R | 1 |
| Tanino, M | 1 |
| Smith, LS | 1 |
| Kajikawa, O | 1 |
| Wong, VA | 1 |
| Mongovin, S | 1 |
| Matute-Bello, G | 1 |
| Martin, TR | 1 |
| Lim, JA | 1 |
| Juhnn, YS | 1 |
| Sarria, B | 1 |
| Naline, E | 1 |
| Zhang, Y | 1 |
| Cortijo, J | 1 |
| Molimard, M | 1 |
| Moreau, J | 1 |
| Therond, P | 1 |
| Advenier, C | 1 |
| Morcillo, EJ | 1 |
| Lavi, S | 1 |
| Aharon-Peretz, J | 1 |
| Haim, N | 1 |
| Vlodavsky, E | 1 |
| Jacob, G | 1 |
| Adissu, HA | 1 |
| Schuller, HM | 3 |
| Plummer, HK | 1 |
| Dhar, MS | 1 |
| Cekanova, M | 1 |
| Laburthe, M | 1 |
| Boissard, C | 1 |
| Chevalier, G | 1 |
| Zweibaum, A | 1 |
| Rosselin, G | 1 |
| Veksler, IG | 1 |
| Riabukha, VN | 1 |
| Smelkova, MI | 1 |
| Balitskiĭ, KP | 1 |
| Shen, BQ | 1 |
| Finkbeiner, WE | 2 |
| Wine, JJ | 2 |
| Mrsny, RJ | 1 |
| Widdicombe, JH | 2 |
| Haws, C | 1 |
| Park, PG | 1 |
| Merryman, J | 1 |
| Orloff, M | 1 |
| Bai, TR | 1 |
| Bramley, AM | 1 |
| Droms, KA | 2 |
| Wittau, N | 1 |
| Grosse, R | 1 |
| Kalkbrenner, F | 1 |
| Gohla, A | 1 |
| Schultz, G | 1 |
| Gudermann, T | 1 |
| Van Den Brenk, HA | 1 |
| Stone, MG | 1 |
| Kelly, H | 1 |
| Sharpington, C | 1 |
| Lange-Carter, CA | 1 |
| Vuillequez, JJ | 1 |
| Malkinson, AM | 1 |
| Nakane, T | 1 |
| Szentendrei, T | 1 |
| Stern, L | 1 |
| Virmani, M | 1 |
| Seely, J | 1 |
| Kunos, G | 1 |
| Palmer, KC | 1 |
| Grammas, P | 1 |
| Cerrina, J | 1 |
| Le Roy Ladurie, M | 1 |
| Labat, C | 1 |
| Raffestin, B | 1 |
| Bayol, A | 1 |
| Brink, C | 1 |
| Marsden, CD | 1 |
| Meadows, JC | 1 |
| Lange, GW | 1 |
| Watson, RS | 1 |
| Kobayashi, T | 1 |
| Nakayama, R | 1 |
| Kimura, K | 1 |
| Yoneyama, T | 1 |
23 other studies available for isoproterenol and Cancer of Lung
| Article | Year |
|---|---|
β2-AR activation promotes cleavage and nuclear translocation of Her2 and metastatic potential of cancer cells.
Topics: ADAM10 Protein; Adrenergic beta-2 Receptor Agonists; Amyloid Precursor Protein Secretases; Animals; | 2020 |
Autophagy suppresses isoprenaline-induced M2 macrophage polarization via the ROS/ERK and mTOR signaling pathway.
Topics: Adenine; Animals; Antibiotics, Antineoplastic; Autophagy; Cell Line, Tumor; Epithelial Cells; Female | 2017 |
The Fas/FasL pathway impairs the alveolar fluid clearance in mouse lungs.
Topics: Acute Lung Injury; Adenoma; Adrenergic beta-Agonists; Animals; Apoptosis; Bronchoalveolar Lavage Flu | 2013 |
Isoproterenol increases histone deacetylase 6 expression and cell migration by inhibiting ERK signaling via PKA and Epac pathways in human lung cancer cells.
Topics: A549 Cells; Cell Line, Tumor; Cell Movement; Cyclic AMP-Dependent Protein Kinases; Epinephrine; Gene | 2016 |
Muscarinic M2 receptors in acetylcholine-isoproterenol functional antagonism in human isolated bronchus.
Topics: Acetylcholine; Bronchi; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoproterenol; Lung Neop | 2002 |
Unusual cause of partially reversible severe cardiovascular autonomic failure.
Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Cardiovascular Diseases; Cardiovascular | 2003 |
Antagonistic growth regulation of cell lines derived from human lung adenocarcinomas of Clara cell and aveolar type II cell lineage: Implications for chemoprevention.
Topics: Adenocarcinoma; Adrenergic beta-Agonists; Bronchi; Cell Division; Cell Lineage; Chemoprevention; Col | 2004 |
Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic | 2005 |
Peptide receptors in human lung tumor cells in culture: vasoactive intestinal peptide (VIP) and secretin interaction with the Calu-1 and SW-900 cell lines.
Topics: 1-Methyl-3-isobutylxanthine; Carcinoma, Squamous Cell; Cell Line; Cyclic AMP; Gastrointestinal Hormo | 1981 |
[Changes in the metastasis of experimental tumors and in the antimetastatic effect of cytostatics in their pharmacological action on adrenergic processes].
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Evaluation, Preclinical; Drug Therapy, Combin | 1984 |
Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl- secretion.
Topics: Bradykinin; Bumetanide; Calcimycin; Cell Line; Cell Membrane; Cell Membrane Permeability; Chloride C | 1994 |
CFTR in Calu-3 human airway cells: channel properties and role in cAMP-activated Cl- conductance.
Topics: Adenosine Triphosphate; Cell Line; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-D | 1994 |
Beta-adrenergic mitogenic signal transduction in peripheral lung adenocarcinoma: implications for individuals with preexisting chronic lung disease.
Topics: Adenocarcinoma; Cell Division; Colforsin; Cyclic AMP; Epinephrine; Humans; In Vitro Techniques; Iodo | 1995 |
Effect of an inhibitor of nitric oxide synthase on neural relaxation of human bronchi.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bronchi; Chymotrypsin; Dose-Response Relationship, Dr | 1993 |
Beta-adrenergic signalling in neoplastic lung type 2 cells: glucocorticoid-dependent and -independent defects.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Dexamethasone; GTP-Binding Proteins; Guanylyl Imid | 1996 |
The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to G(q), G(i) and G(12) proteins.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Actin Cytoskeleton; Actins; Animals; Calcium Signaling; Carc | 2000 |
Lowering of innate resistance of the lungs to the growth of blood-borne cancer cells in states of topical and systemic stress.
Topics: Adrenalectomy; Aminophylline; Anesthesia; Animals; Carcinoma 256, Walker; Cell Survival; Clone Cells | 1976 |
Differential responsiveness to agents which stimulate cAMP production in normal versus neoplastic mouse lung epithelial cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Epithelial Cells; Epith | 1992 |
Effects of IL-1 and cortisol on beta-adrenergic receptors, cell proliferation, and differentiation in cultured human A549 lung tumor cells.
Topics: Cell Adhesion; Cell Differentiation; Cell Division; Cyclic AMP; Cycloheximide; Dose-Response Relatio | 1990 |
Beta-adrenergic regulation of secretion from Clara cell adenomas of the mouse lung.
Topics: Adenoma; Animals; Cytoplasmic Granules; Female; Iodocyanopindolol; Isoproterenol; Lung Neoplasms; Mi | 1987 |
Comparison of human bronchial muscle responses to histamine in vivo with histamine and isoproterenol agonists in vitro.
Topics: Adult; Aged; Airway Resistance; Bronchi; Bronchial Provocation Tests; Carcinoma; Female; Forced Expi | 1986 |
Effect of deafferentation on human physiological tremor.
Topics: Arm; Denervation; Epinephrine; Feedback; Female; Fingers; Horner Syndrome; Humans; Infusions, Parent | 1967 |
Cardiovascular responses to intravenous isoproterenol infusion in subjects with and without left ventricular hypertrophy.
Topics: Blood Pressure; Cardiac Output; Heart; Heart Diseases; Heart Rate; Heart Ventricles; Humans; Hypertr | 1970 |