Page last updated: 2024-10-29

isoproterenol and Burns

isoproterenol has been researched along with Burns in 15 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
"Alprenolol (10 microM) was used to determine nonspecific binding."1.29Characterization of cardiac beta-adrenergic receptors in the guinea pig heart: application to study of beta-adrenergic receptors in shock models. ( Horton, JW; Kaufman, TM, 1993)
"Pretreatment with ritanserin, BW A1433U83, atropine, ICI 118551, diphenhydramine, ranitidine, meclofenamate, L-nitro-arginine methyl ester, 3-amino-1,2,4-triazine, and U 37883A had no effect on the increased femoral blood flow response to scald, suggesting this vasodilator response is not dependent upon activation of serotonergic2, adenosineA1, muscarinic, beta 2-adrenergic, histaminergic1 or histaminergic2 receptors, on cyclooxygenase products, endothelium-derived relaxing factor derived from nitric oxide (NO) synthase III, NO derived from NO synthase II, or KATP channels, respectively."1.29Analysis of regional hemodynamic regulation in response to scald injury. ( Ferrara, JJ; Flint, LM; Force, SD; Franklin, EW; Hyman, AL; Lippton, HL; Taheri, PA, 1994)
" Isoproterenol dose-response curves were generated in isolated perfused hearts from sham-burned and burned guinea pigs."1.28Burn-induced alterations in cardiac beta-adrenergic receptors. ( Horton, JW; Kaufman, TM, 1992)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's9 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colombo, JL1
Hopkins, RL1
Waring, WW1
Kaufman, TM3
Horton, JW7
Taheri, PA1
Lippton, HL1
Force, SD1
Franklin, EW1
Hyman, AL1
Flint, LM1
Ferrara, JJ1
White, DJ3
Mahony, L1
Wang, C1
Martyn, JA1
Koshy, US1
Burton, KP1
Le, TH1
Xia, ZF1
Zhao, P1
Lin, C1
Sherry, AD1
Malloy, CR1
Aprille, JR1
Aikawa, N1
Bell, TC1
Bode, HH1
Malamud, DF1
Loegering, DJ1
Commins, LM1
Wilmore, DW1
Long, JM1
Mason, AD1
Skreen, RW1
Pruitt, BA1
Stoner, HB1
Moncrief, JA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Acute Burn Resuscitation Multicenter Prospective Observational Trial[NCT03144427]400 participants (Actual)Observational2017-02-24Completed
The Acute Burn ResUscitation Multicenter Prospective Trial (ABRUPT2)[NCT04356859]400 participants (Anticipated)Interventional2021-04-22Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

15 other studies available for isoproterenol and Burns

ArticleYear
Steam vaporizer injuries.
    Pediatrics, 1981, Volume: 67, Issue:5

    Topics: Aminophylline; Burns; Child, Preschool; Dexamethasone; Drug Therapy, Combination; Facial Injuries; F

1981
Characterization of cardiac beta-adrenergic receptors in the guinea pig heart: application to study of beta-adrenergic receptors in shock models.
    The Journal of surgical research, 1993, Volume: 55, Issue:5

    Topics: Alprenolol; Animals; Binding, Competitive; Burns; Cell Membrane; Filtration; Guanylyl Imidodiphospha

1993
Analysis of regional hemodynamic regulation in response to scald injury.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: Adamantane; Animals; Arginine; Atropine; Blood Pressure; Burns; Diphenhydramine; Dogs; Femoral Arter

1994
Diminished cardiac contractile response to burn injury in aged guinea pigs.
    The Journal of trauma, 1993, Volume: 34, Issue:3

    Topics: Aging; Animals; Burns; Calcium Channels; Depression, Chemical; Diltiazem; Guinea Pigs; Isoproterenol

1993
Cardiac contractile and calcium transport function after burn injury in adult and aged guinea pigs.
    The Journal of surgical research, 1993, Volume: 55, Issue:1

    Topics: Aging; Animals; Biological Transport; Blood Pressure; Burns; Calcium; Electric Stimulation; Guinea P

1993
Burn injury alters beta-adrenergic receptor and second messenger function in rat ventricular muscle.
    Critical care medicine, 1996, Volume: 24, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Burns; Cell Membrane; Colforsin; Cyclic AMP; Heart Ventricles; In

1996
Altered ionic calcium and cell motion in ventricular myocytes after cutaneous thermal injury.
    The Journal of surgical research, 1997, Volume: 68, Issue:2

    Topics: Animals; Burns; Caffeine; Calcium; Cardiotonic Agents; Cations, Divalent; Cell Movement; Central Ner

1997
Relationship between energetic, ionic, and functional status in the perfused rat heart following thermal injury: a 31P and 23Na NMR study.
    The Journal of surgical research, 1997, Volume: 69, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Burns; Calcium; Energy Metabolism; Heart; Heart Injuries; In Vitr

1997
Adenylate cyclase after burn injury: resistance to desensitization by catecholamines.
    The Journal of trauma, 1979, Volume: 19, Issue:11

    Topics: Adenylyl Cyclases; Animals; Burns; Cold Temperature; Desensitization, Immunologic; Isoproterenol; Ma

1979
Burn-induced alterations in cardiac beta-adrenergic receptors.
    The American journal of physiology, 1992, Volume: 262, Issue:5 Pt 2

    Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Burns; Catecholamines; Dose-Response Relati

1992
Hypertonic saline dextran resuscitation fails to improve cardiac function in neonatal and senescent burned guinea pigs.
    The Journal of trauma, 1991, Volume: 31, Issue:11

    Topics: Age Factors; Animals; Animals, Newborn; Burns; Coronary Circulation; Dextrans; Guinea Pigs; Heart; H

1991
Effect of beta-receptor stimulation on Kupffer cell complement receptor clearance function.
    Circulatory shock, 1988, Volume: 25, Issue:4

    Topics: Animals; Burns; Epinephrine; Isoproterenol; Kupffer Cells; Male; Norepinephrine; Propranolol; Rats;

1988
Catecholamines: mediator of the hypermetabolic response to thermal injury.
    Annals of surgery, 1974, Volume: 180, Issue:4

    Topics: Adolescent; Adult; Aged; Body Surface Area; Body Temperature; Body Temperature Regulation; Burns; Ca

1974
3. Metabolism, heat loss and toxic factors. Mechanism of body temperature changes after burns and other injuries.
    Annals of the New York Academy of Sciences, 1968, Aug-14, Volume: 150, Issue:3

    Topics: Acclimatization; Animals; Body Temperature Regulation; Body Weight; Burns; Cold Temperature; Colon;

1968
Effect of various fluid regimens and pharmacologic agents on the circulatory hemodynamics of the immediate postburn period.
    Annals of surgery, 1966, Volume: 164, Issue:4

    Topics: Animals; Blood Pressure; Burns; Cardiac Output; Dextrans; Dogs; Glucose; Hematocrit; Hydralazine; Is

1966
Effect of various fluid regimens and pharmacologic agents on the circulatory hemodynamics of the immediate postburn period.
    Annals of surgery, 1966, Volume: 164, Issue:4

    Topics: Animals; Blood Pressure; Burns; Cardiac Output; Dextrans; Dogs; Glucose; Hematocrit; Hydralazine; Is

1966
Effect of various fluid regimens and pharmacologic agents on the circulatory hemodynamics of the immediate postburn period.
    Annals of surgery, 1966, Volume: 164, Issue:4

    Topics: Animals; Blood Pressure; Burns; Cardiac Output; Dextrans; Dogs; Glucose; Hematocrit; Hydralazine; Is

1966
Effect of various fluid regimens and pharmacologic agents on the circulatory hemodynamics of the immediate postburn period.
    Annals of surgery, 1966, Volume: 164, Issue:4

    Topics: Animals; Blood Pressure; Burns; Cardiac Output; Dextrans; Dogs; Glucose; Hematocrit; Hydralazine; Is

1966