isoproterenol has been researched along with Breast Cancer in 13 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among these breast cancers those that are estrogen-responsive respond well to existing therapeutic regimens while estrogen non-responsive cancers metastasize widely, demonstrate a high relapse rate, and respond poorly to therapy." | 5.31 | Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines. ( Cakir, Y; Plummer, HK; Schuller, HM; Tithof, PK, 2002) |
| "Using L-[3H]dihydroalprenolol [( 3H]DHA), a potent beta-adrenergic antagonist, we demonstrated in breast cancer cells the presence of beta-adrenergic receptors with high affinity (Kd 1-9 nM) as shown by Scatchard analyses." | 3.68 | Functional beta-adrenergic receptors in breast cancer cells. ( Lefebvre, J; Revillion, F; Vandewalle, B, 1990) |
| "Furthermore, we report that breast cancer cell migration is decreased by the FDA-approved β-blocker, propranolol." | 1.42 | β-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells. ( Lorimer, E; Tyburski, MD; Williams, CL; Wilson, JM, 2015) |
| "Breast cancer is the most frequent malignancy in women." | 1.40 | Differential β₂-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines. ( Bruzzone, A; Copsel, S; Davio, C; Galés, C; Gargiulo, L; Lüthy, IA; Rivero, EM; Sénard, JM, 2014) |
| "MDA-MB-231 human breast cancer cells express high beta-adrenoceptor levels, predominantly the beta2 subtype." | 1.31 | Beta-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells. ( Dancel, R; Garcia, SJ; Seidler, FJ; Slotkin, TA; Willis, C; Zhang, J, 2000) |
| "Among these breast cancers those that are estrogen-responsive respond well to existing therapeutic regimens while estrogen non-responsive cancers metastasize widely, demonstrate a high relapse rate, and respond poorly to therapy." | 1.31 | Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines. ( Cakir, Y; Plummer, HK; Schuller, HM; Tithof, PK, 2002) |
| "The effect of estradiol treatment of the human mammary carcinoma cell MCF-7 on the adenylyl cyclase system was examined." | 1.29 | Estradiol up-regulates the stimulatory GTP-binding protein expression in the MCF-7 human mammary carcinoma cell line. ( Kimura, N; Nagata, N; Shimada, N; Yasutomo, Y, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, D | 2 |
| Zha, L | 1 |
| Liu, Y | 1 |
| Zhao, X | 1 |
| Xu, X | 1 |
| Liu, S | 1 |
| Ma, W | 1 |
| Zheng, J | 1 |
| Shi, M | 2 |
| Gargiulo, L | 2 |
| Copsel, S | 2 |
| Rivero, EM | 2 |
| Galés, C | 1 |
| Sénard, JM | 1 |
| Lüthy, IA | 3 |
| Davio, C | 2 |
| Bruzzone, A | 3 |
| Wilson, JM | 1 |
| Lorimer, E | 1 |
| Tyburski, MD | 1 |
| Williams, CL | 1 |
| May, M | 1 |
| Lamb, C | 1 |
| Lydon, J | 1 |
| Lanari, C | 1 |
| Duan, H | 1 |
| Qian, L | 1 |
| Wang, L | 1 |
| Niu, L | 1 |
| Zhang, H | 1 |
| Yong, Z | 1 |
| Gong, Z | 1 |
| Song, L | 1 |
| Yu, M | 1 |
| Hu, M | 1 |
| Xia, Q | 1 |
| Shen, B | 1 |
| Guo, N | 1 |
| Pérez Piñero, C | 1 |
| Sarappa, MG | 1 |
| Castillo, LF | 1 |
| García-Solís, P | 1 |
| Aceves, C | 1 |
| STRATFORD, EC | 1 |
| TANAKA, KR | 1 |
| Yasutomo, Y | 1 |
| Shimada, N | 1 |
| Kimura, N | 1 |
| Nagata, N | 1 |
| Slotkin, TA | 1 |
| Zhang, J | 1 |
| Dancel, R | 1 |
| Garcia, SJ | 1 |
| Willis, C | 1 |
| Seidler, FJ | 1 |
| Cakir, Y | 1 |
| Plummer, HK | 1 |
| Tithof, PK | 1 |
| Schuller, HM | 1 |
| Vandewalle, B | 1 |
| Revillion, F | 1 |
| Lefebvre, J | 1 |
| Wu, TL | 1 |
| Insogna, KL | 1 |
| Hough, LM | 1 |
| Milstone, L | 1 |
| Stewart, AF | 1 |
13 other studies available for isoproterenol and Breast Cancer
| Article | Year |
|---|---|
β2-AR activation promotes cleavage and nuclear translocation of Her2 and metastatic potential of cancer cells.
Topics: ADAM10 Protein; Adrenergic beta-2 Receptor Agonists; Amyloid Precursor Protein Secretases; Animals; | 2020 |
Differential β₂-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines.
Topics: Adrenergic beta-2 Receptor Agonists; Breast Neoplasms; Cell Adhesion; Cell Line; Cell Line, Tumor; C | 2014 |
β-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Antagonists; Aminopyridines; Breast Neoplasms; | 2015 |
A Novel Effect of β-Adrenergic Receptor on Mammary Branching Morphogenesis and its Possible Implications in Breast Cancer.
Topics: Animals; Breast Neoplasms; Catecholamines; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Ce | 2017 |
The β2-adrenergic receptor and Her2 comprise a positive feedback loop in human breast cancer cells.
Topics: Base Sequence; Blotting, Western; Breast Neoplasms; Catecholamines; Cell Line, Tumor; Epinephrine; E | 2011 |
Involvement of α2- and β2-adrenoceptors on breast cancer cell proliferation and tumour growth regulation.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Albuterol; Animals; Antineoplastic Agents; Breast Neopl | 2012 |
5'Deiodinase in two breast cancer cell lines: effect of triiodothyronine, isoproterenol and retinoids.
Topics: Adrenergic beta-Agonists; Breast Neoplasms; Cell Differentiation; DNA Primers; Female; Humans; Iodid | 2003 |
MICROANGIOPATHIC HEMOLYTIC ANEMIA IN METASTATIC CARCINOMA. REPORT OF A CASE AND BIOCHEMICAL STUDIES.
Topics: Anemia, Hemolytic; Bone Marrow Cells; Breast Neoplasms; Chemical Phenomena; Chemistry; Clinical Enzy | 1965 |
Estradiol up-regulates the stimulatory GTP-binding protein expression in the MCF-7 human mammary carcinoma cell line.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Breast Neoplasms; Calcitonin; Cholera Toxin; Colforsin; | 1993 |
Beta-adrenoceptor signaling and its control of cell replication in MDA-MB-231 human breast cancer cells.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Analysis of Variance; Anti-Inflammatory Agents; Breast | 2000 |
Beta-adrenergic and arachidonic acid-mediated growth regulation of human breast cancer cell lines.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Arachidonate 5-Lipoxygenase; Arachidonic Acid | 2002 |
Functional beta-adrenergic receptors in breast cancer cells.
Topics: Breast Neoplasms; Cyclic AMP; Dihydroalprenolol; Female; Humans; Isoproterenol; Receptors, Adrenergi | 1990 |
Skin-derived fibroblasts respond to human parathyroid hormone-like adenylate cyclase-stimulating proteins.
Topics: Adenylyl Cyclases; Breast Neoplasms; Cells, Cultured; Cyclic AMP; Enzyme Activation; Fibroblasts; Hu | 1987 |