Page last updated: 2024-10-29

isoproterenol and Brain Neoplasms

isoproterenol has been researched along with Brain Neoplasms in 14 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells displays many characteristics observed in brain tissue: using nonlinear regression analysis of agonist competition binding curves, we demonstrated that the bulk of beta-adrenoceptors show high nanomolar affinity for isoproterenol; like in brain tissue, Gpp(NH)p does not shift agonist competition binding curves to the right; and the agonist isoproterenol rapidly downregulates the number of beta-adrenoceptors and deamplifies the norepinephrine signal."7.68The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells. Deamplification by isoproterenol and oxaprotiline. ( Bieck, PR; Duhl, DM; Gillespie, DD; Manier, DH; Sulser, F, 1992)
" Rat C6 glioma cells were stimulated with isoproterenol and the protein lysates were resolved by 2-DGE."3.70Probing for drug-induced multiplex signal transduction pathways using high resolution two-dimensional gel electrophoresis: application to beta-adrenoceptor stimulation in the rat C6 glioma cell. ( Khawaja, XZ; Storm, SM, 1999)
"The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells displays many characteristics observed in brain tissue: using nonlinear regression analysis of agonist competition binding curves, we demonstrated that the bulk of beta-adrenoceptors show high nanomolar affinity for isoproterenol; like in brain tissue, Gpp(NH)p does not shift agonist competition binding curves to the right; and the agonist isoproterenol rapidly downregulates the number of beta-adrenoceptors and deamplifies the norepinephrine signal."3.68The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells. Deamplification by isoproterenol and oxaprotiline. ( Bieck, PR; Duhl, DM; Gillespie, DD; Manier, DH; Sulser, F, 1992)
"Rat C 6 glioma is known to possess a beta-adrenergic receptor with which intracellular cyclic adenosine monophosphate (cAMP) levels are altered to control cell growth in vitro."1.27[Treatment of rat glioma with a beta-adrenergic agonist and a phosphodiesterase inhibitor in vivo]. ( Egawa, T; Hayakawa, T; Mogami, H; Sakamoto, Y; Shimizu, K; Ushio, Y; Yoshida, T, 1987)
"The atropine test was found to be an efficient and simple diagnostic aid in cases of brain death."1.25Electrocardiographic findings in brain death; description and presumed mechanism. ( Drory, Y; Kellermann, JJ; Kosary, IZ; Ouaknine, G, 1975)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's3 (21.43)18.2507
2000's0 (0.00)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wnorowski, A1
Such, J1
Paul, RK1
Wersto, RP1
Indig, FE1
Jozwiak, K1
Bernier, M1
Wainer, IW1
Chelmicka-Schorr, E1
Arnason, BG1
Holshouser, SJ1
Canova, C1
Baudet, C1
Chevalier, G1
Brachet, P1
Wion, D1
Storm, SM1
Khawaja, XZ1
Perkins, JP1
Moore, MM1
Kalisker, A1
Su, YF1
Lazarewicz, JW1
Kanje, M1
Sellström, A1
Hamberger, A1
Drory, Y1
Ouaknine, G1
Kosary, IZ1
Kellermann, JJ1
Manier, DH1
Bieck, PR1
Duhl, DM1
Gillespie, DD1
Sulser, F1
Yoshida, T1
Shimizu, K1
Ushio, Y1
Hayakawa, T1
Mogami, H1
Sakamoto, Y1
Egawa, T1
Magun, JG1
Shimizu, H2
Tanaka, S1
Suzuki, T1
Matsukado, Y2
Schimmer, BP1
Kodama, T1
Beaufils, F1
Bousser, P1
Chapman, A1

Reviews

1 review available for isoproterenol and Brain Neoplasms

ArticleYear
Regulation of cyclic AMP content in normal and malignant brain cells.
    Advances in cyclic nucleotide research, 1975, Volume: 5

    Topics: Adenosine; Animals; Brain; Brain Neoplasms; Cerebral Cortex; Cyclic AMP; Hydroxydopamines; Isoproter

1975

Other Studies

13 other studies available for isoproterenol and Brain Neoplasms

ArticleYear
Concurrent activation of β
    Cellular signalling, 2017, Volume: 36

    Topics: Animals; Apoptosis; Brain Neoplasms; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Movement; Ce

2017
C-6 glioma growth in rats: suppression with a beta-adrenergic agonist and a phosphodiesterase inhibitor.
    Annals of neurology, 1980, Volume: 8, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line; Cyclic AMP; Drug Therapy, Combination; Glioma; Humans; Isoprote

1980
Noradrenaline inhibits the programmed cell death induced by 1,25-dihydroxyvitamin D3 in glioma.
    European journal of pharmacology, 1997, Jan-29, Volume: 319, Issue:2-3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Apoptosis; Brain Neoplasms; Calcitri

1997
Probing for drug-induced multiplex signal transduction pathways using high resolution two-dimensional gel electrophoresis: application to beta-adrenoceptor stimulation in the rat C6 glioma cell.
    Brain research. Molecular brain research, 1999, Jul-23, Volume: 71, Issue:1

    Topics: Animals; Brain Neoplasms; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; Glioma; Isoproterenol;

1999
Calcium fluxes in cultured and bulk isolated neuronal and glial cells.
    Journal of neurochemistry, 1977, Volume: 29, Issue:3

    Topics: Acetylcholine; Animals; Astrocytes; Brain Neoplasms; Calcium; Cells, Cultured; Choline; Glioma; Huma

1977
Electrocardiographic findings in brain death; description and presumed mechanism.
    Chest, 1975, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Aged; Atropine; Brain Death; Brain Neoplasms; Child; Child, Preschool; Craniocere

1975
The beta-adrenoceptor-coupled adenylate cyclase system in rat C6 glioma cells. Deamplification by isoproterenol and oxaprotiline.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1992, Volume: 7, Issue:2

    Topics: Adenylyl Cyclases; Animals; Antidepressive Agents; Autoradiography; Blotting, Northern; Brain Neopla

1992
[Treatment of rat glioma with a beta-adrenergic agonist and a phosphodiesterase inhibitor in vivo].
    No to shinkei = Brain and nerve, 1987, Volume: 39, Issue:8

    Topics: Animals; Brain Neoplasms; Cyclic AMP; Glioma; Injections, Spinal; Isoproterenol; Meningeal Neoplasms

1987
The effect of pharmacologically increased blood pressure on brain circulation. Angiographic investigation of arterial diameter and blood flow in patients with normal and pathological angiograms.
    Zeitschrift fur Neurologie, 1973, Apr-02, Volume: 204, Issue:2

    Topics: Absorptiometry, Photon; Anthropometry; Blood Pressure; Brain Injuries; Brain Neoplasms; Carotid Arte

1973
The response of human cerebrum adenyl cyclase to biogenic amines.
    Journal of neurochemistry, 1971, Volume: 18, Issue:6

    Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Brain Neoplasms; C

1971
Effects of catecholamines and monovalent cations on adenylate cyclase activity in cultured glial tumor cells.
    Biochimica et biophysica acta, 1971, Dec-21, Volume: 252, Issue:3

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Brain Neoplasms; Ca

1971
The cyclic AMP system of human brain.
    Brain research, 1973, Feb-14, Volume: 50, Issue:1

    Topics: Adenine; Adenosine; Adenylyl Cyclases; Adult; Aged; Brain; Brain Chemistry; Brain Neoplasms; Carbon

1973
[Electrocardiographic changes and severe rhythm disorders during meningeal hemorrhages or after neurosurgical intervention].
    La Nouvelle presse medicale, 1974, Mar-02, Volume: 3, Issue:9

    Topics: Adult; Aneurysm; Basilar Artery; Bradycardia; Brain Neoplasms; Cerebral Arteries; Electric Countersh

1974