isoproterenol has been researched along with Bladder, Overactive in 7 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These compounds have been identified as potent and selective human beta(3)-AR agonists with improved oral bioavailability compared to the previous series." | 1.35 | Discovery of highly potent and selective biphenylacylsulfonamide-based beta3-adrenergic receptor agonists and evaluation of physical properties as potential overactive bladder therapies: part 5. ( Araki, T; Hamada, K; Hamashima, H; Hattori, K; Imamura, E; Imanishi, M; Ishikawa, H; Itou, S; Matsui, S; Matsumura, Y; Nakajima, Y; Nakano, K; Sakurai, M; Takamura, F; Toda, S; Tomishima, Y; Ueshima, K; Unami, N; Washizuka, K; Yamamoto, N; Yamamoto, T, 2009) |
| "L-carnitine treatment restored the hyporesponsiveness of isoprenaline and the hyperresponsiveness of adenosine-elicited relaxation." | 1.35 | L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats. ( Gur, S; Irat, AM, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hattori, K | 1 |
| Toda, S | 1 |
| Imanishi, M | 1 |
| Itou, S | 1 |
| Nakajima, Y | 1 |
| Washizuka, K | 1 |
| Araki, T | 1 |
| Hamashima, H | 1 |
| Tomishima, Y | 1 |
| Sakurai, M | 1 |
| Matsui, S | 1 |
| Imamura, E | 1 |
| Ueshima, K | 1 |
| Yamamoto, T | 1 |
| Yamamoto, N | 1 |
| Ishikawa, H | 1 |
| Nakano, K | 1 |
| Unami, N | 1 |
| Hamada, K | 1 |
| Matsumura, Y | 1 |
| Takamura, F | 1 |
| Michel, MC | 2 |
| Gur, S | 1 |
| Irat, AM | 1 |
| Otsuka, A | 1 |
| Shinbo, H | 1 |
| Hasebe, K | 1 |
| Matsumoto, R | 1 |
| Ozono, S | 1 |
| Sand, C | 1 |
| Maruyama, I | 1 |
| Goi, Y | 1 |
| Tatemichi, S | 1 |
| Maruyama, K | 1 |
| Hoyano, Y | 1 |
| Yamazaki, Y | 1 |
| Kusama, H | 1 |
| Svalø, J | 1 |
| Nordling, J | 1 |
| Bouchelouche, K | 1 |
| Andersson, KE | 1 |
| Korstanje, C | 1 |
| Bouchelouche, P | 1 |
7 other studies available for isoproterenol and Bladder, Overactive
| Article | Year |
|---|---|
Discovery of highly potent and selective biphenylacylsulfonamide-based beta3-adrenergic receptor agonists and evaluation of physical properties as potential overactive bladder therapies: part 5.
Topics: Adrenergic beta-3 Receptor Agonists; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Drug Di | 2009 |
Do β-adrenoceptor agonists induce homologous or heterologous desensitization in rat urinary bladder?
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; | 2014 |
L-carnitine treatment partially restores urinary bladder function of streptozotocin diabetic rats.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Bloo | 2008 |
Effects of a novel beta(3)-adrenoceptor agonist, AJ-9677, on relaxation of the detrusor muscle: an in vitro study.
Topics: Acetates; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Animals; Dioxoles; Female; Human | 2008 |
Effect of pre-contraction on β-adrenoceptor-mediated relaxation of rat urinary bladder.
Topics: Adrenergic beta-Agonists; Animals; Bradykinin; Carbachol; Colforsin; Dose-Response Relationship, Dru | 2009 |
Bladder selectivity of the novel β₃-agonist ritobegron (KUC-7483) explored by in vitro and in vivo studies in the rat.
Topics: Acetates; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-3 Receptor Antagonists; Adrenergic be | 2012 |
The novel β3-adrenoceptor agonist mirabegron reduces carbachol-induced contractile activity in detrusor tissue from patients with bladder outflow obstruction with or without detrusor overactivity.
Topics: Acetanilides; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Aged; Aged, 80 and over | 2013 |