isoproterenol has been researched along with Asymmetric Septal Hypertrophy, Familial in 8 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arrhythmias were attenuated with the β-blocker atenolol and protein kinase A inhibitor PKI." | 1.91 | Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a model of hypertrophic cardiomyopathy. ( Barratt Ross, S; Cserne Szappanos, H; Dixon, RE; Hill, A; Holliday, M; Hool, LC; Ito, DW; Lim, S; Mangala, M; Semsarian, C; Viola, HM, 2023) |
| "Troponin T (TnT) mutations that cause familial hypertrophic cardiomyopathy (FHC) and sudden cardiac death frequently increase myofilament Ca2+ sensitivity, suggesting that their Ca2+-sensitizing effect contributes importantly to the FHC pathogenesis." | 1.33 | Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase. ( Knollmann, BC; Potter, JD; Sirenko, SG, 2006) |
| "Sudden cardiac death is related to adrenergic stress and is independent of the development of fibrosis but occurred only in male mice." | 1.32 | Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T. ( Ikeda, K; Leinwand, LA; Maass, AH; Maier, SK; Oberdorf-Maass, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Cserne Szappanos, H | 1 |
| Viola, HM | 1 |
| Ito, DW | 1 |
| Lim, S | 1 |
| Mangala, M | 1 |
| Holliday, M | 1 |
| Barratt Ross, S | 1 |
| Semsarian, C | 1 |
| Hill, A | 1 |
| Dixon, RE | 1 |
| Hool, LC | 1 |
| Peña, JR | 1 |
| Szkudlarek, AC | 1 |
| Warren, CM | 1 |
| Heinrich, LS | 1 |
| Gaffin, RD | 1 |
| Jagatheesan, G | 2 |
| del Monte, F | 1 |
| Hajjar, RJ | 1 |
| Goldspink, PH | 1 |
| Solaro, RJ | 2 |
| Wieczorek, DF | 3 |
| Wolska, BM | 1 |
| Knollmann, BC | 2 |
| Kirchhof, P | 1 |
| Sirenko, SG | 2 |
| Degen, H | 1 |
| Greene, AE | 1 |
| Schober, T | 1 |
| Mackow, JC | 1 |
| Fabritz, L | 1 |
| Potter, JD | 2 |
| Morad, M | 1 |
| WHALEN, RE | 1 |
| COHEN, AI | 1 |
| SUMNER, RG | 1 |
| McINTOSH, HD | 1 |
| Prabhakar, R | 1 |
| Petrashevskaya, N | 2 |
| Schwartz, A | 2 |
| Aronow, B | 1 |
| Boivin, GP | 1 |
| Molkentin, JD | 1 |
| Maass, AH | 1 |
| Ikeda, K | 1 |
| Oberdorf-Maass, S | 1 |
| Maier, SK | 1 |
| Leinwand, LA | 1 |
| Rajan, S | 1 |
| Boivin, G | 1 |
| Arteaga, GM | 1 |
| Liggett, SB | 1 |
8 other studies available for isoproterenol and Asymmetric Septal Hypertrophy, Familial
| Article | Year |
|---|---|
Cytoskeletal disarray increases arrhythmogenic vulnerability during sympathetic stimulation in a model of hypertrophic cardiomyopathy.
Topics: Animals; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Cardiomyopathy, Hypertrophic, Familial; | 2023 |
Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy.
Topics: Actin Cytoskeleton; Adenoviridae; Animals; Animals, Newborn; Atrial Natriuretic Factor; Calcium-Bind | 2010 |
Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling.
Topics: Action Potentials; Anesthesia; Animals; Blood Pressure; Calcium; Cardiomyopathy, Hypertrophic, Famil | 2003 |
Demonstration of the dynamic nature of idiopathic hypertrophic subaortic stenosis.
Topics: Aortic Valve Stenosis; Cardiomyopathy, Hypertrophic; Cardiomyopathy, Hypertrophic, Familial; Constri | 1963 |
A mouse model of familial hypertrophic cardiomyopathy caused by a alpha-tropomyosin mutation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Body Weight; Cardiomyopathy, Hypertrophic, Familial; Ca | 2003 |
Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Amino Acid Substitution; Angiotensin II; Animal | 2004 |
Differential effect of troponin T mutations on the inotropic responsiveness of mouse hearts--role of myofilament Ca2+ sensitivity increase.
Topics: Actin Cytoskeleton; Adrenergic beta-Antagonists; Animals; Calcium; Cardiomyopathy, Hypertrophic, Fam | 2006 |
Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis.
Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Animals; Calcium; Cardiomyopathy, Hypertrophic, Famili | 2007 |