isoproterenol has been researched along with Astrocytoma in 64 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Substance P (SP) stimulated [3H]taurine release from human astrocytoma cells (U-373 MG)." | 7.68 | Effects of tachykinins on [3H]taurine release from human astrocytoma cells (U-373 MG). ( Lee, CM; Tung, WL, 1991) |
| "The ligand-induced internalization of beta-adrenergic receptors and the receptor-mediated internalization of epidermal growth factor were blocked, under similar conditions, by phenylarsine oxide (PAO) in human astrocytoma cells (1321N1)." | 7.67 | A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide. ( Coulter, SJ; Hertel, C; Perkins, JP, 1985) |
| "Incubation of human astrocytoma cells (1321N1) with low concentrations of isoproterenol results in a specific loss of responsiveness to catecholamines as evidenced by a decreased accumulation of cAMP in intact cells, a reduction in isoproterenol-stimulated adenylate cyclase activity, and a decrease in beta-adrenergic receptor density, as measured by the specific binding of 125I-hydroxybenzylpindolol." | 7.66 | Isoproterenol-induced desensitization of adenylate cyclase in human astrocytoma cells. Relation of loss of hormonal responsiveness and decrement in beta-adrenergic receptors. ( Harden, TK; Perkins, JP; Su, YF, 1979) |
| " In 1321N1 human astrocytoma cells, the endogenous PDE1 (identified as PDE1A by reverse transcriptase-PCR) was largely insensitive to Ca2+ released from carbachol-sensitive stores but was robustly stimulated by a similar rise in [Ca2+]i due to carbachol-induced Ca2+ influx." | 3.72 | Sustained entry of Ca2+ is required to activate Ca2+-calmodulin-dependent phosphodiesterase 1A. ( Ciruela, A; Cooper, DM; Goraya, TA; Masada, N, 2004) |
| " In human astrocytoma 1321N1 cells RGS2 expression was increased by activation of muscarinic receptors coupled to phosphoinositide signaling with carbachol, or by increased cyclic AMP production, demonstrating that both signaling systems can increase the expression of a RGS family member in a single cell type." | 3.71 | Second messengers regulate RGS2 expression which is targeted to the nucleus. ( Cobbs, CS; Harkins, L; Jope, RS; Song, L; Zmijewski, JW, 2001) |
| "Pretreatment of 1321N1 human astrocytoma cells with exogenously added bacterial phospholipase C (PLC) induced an increase in subsequent stimulation of cyclic AMP accumulation by the beta-adrenergic receptor agonist isoproterenol and by the direct adenylyl cyclase activator forskolin, a phenomenon referred to as sensitization." | 3.69 | Modulation of cyclic AMP accumulation in glial cells by exogenous phospholipase C. ( Hoffman, J; Toews, M; Whittle, S, 1996) |
| "Exposure of 1321N1 human astrocytoma cells to fresh medium containing fetal bovine serum induced a marked increase in the subsequent ability of isoproterenol and forskolin to stimulate cAMP accumulation in intact cells, compared with cells exposed to fresh medium without serum." | 3.68 | Serum-induced sensitization of cyclic AMP accumulation in 1321N1 human astrocytoma cells. ( Arneson-Rotert, LJ; Hoffman, JM; Johnson, RA; Toews, ML, 1991) |
| "Substance P (SP) stimulated [3H]taurine release from human astrocytoma cells (U-373 MG)." | 3.68 | Effects of tachykinins on [3H]taurine release from human astrocytoma cells (U-373 MG). ( Lee, CM; Tung, WL, 1991) |
| "Competition by beta-adrenergic agonists and antagonists for 125I-pindolol binding sites on intact cells (1321N1 human astrocytoma and C62B rat glioma) was measured using short time binding assays as previously described (Toews, M." | 3.67 | Agonist-induced changes in beta-adrenergic receptors on intact cells. ( Perkins, JP; Toews, ML, 1984) |
| "Agonist occupation of muscarinic cholinergic receptors of 1321N1 human astrocytoma cells results in an activation of phosphodiesterase and a resultant 50-75% attenuation of isoproterenol-stimulated cyclic AMP accumulation." | 3.67 | Identification of the phosphodiesterase regulated by muscarinic cholinergic receptors of 1321N1 human astrocytoma cells. ( Harden, TK; Martin, MW; Tanner, LI; Wells, JN, 1986) |
| "C6-2B rat astrocytoma cells were used to test whether the increase of cellular nerve growth factor (NGF) content and secretion induced by isoproterenol treatment are associated with an increase in the content of mRNA that encodes NGF (NGF mRNA)." | 3.67 | Beta adrenergic and prostaglandin receptor activation increases nerve growth factor mRNA content in C6-2B rat astrocytoma cells. ( Brooker, G; Costa, E; Dal Toso, R; De Bernardi, MA; Mocchetti, I, 1988) |
| "In C6-2B astrocytoma cells the Beta NGF content and secretion rate are increased by isoproterenol activation of beta-adrenergic receptors (Schwartz and Costa, 1977)." | 3.67 | Beta-adrenergic receptor regulation of NGF-mRNA content in rat C6-2B glioma cells. ( Costa, E; Dal Toso, R; De Bernardi, MA; Mocchetti, I, 1987) |
| "The ligand-induced internalization of beta-adrenergic receptors and the receptor-mediated internalization of epidermal growth factor were blocked, under similar conditions, by phenylarsine oxide (PAO) in human astrocytoma cells (1321N1)." | 3.67 | A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide. ( Coulter, SJ; Hertel, C; Perkins, JP, 1985) |
| "Beta-Adrenergic receptors and epidermal growth factor receptors are both expressed on the cell surface of human astrocytoma cells." | 3.67 | The involvement of cellular ATP in receptor-mediated internalization of epidermal growth factor and hormone-induced internalization of beta-adrenergic receptors. ( Coulter, SJ; Hertel, C; Perkins, JP, 1986) |
| "Digitonin-permeabilized monolayers of C6-2B rat astrocytoma cells exhibit adenylate cyclase activity in the presence of exogenously added ATP." | 3.67 | Maintenance of whole cell isoproterenol and forskolin responsiveness in adenylate cyclase of permeabilized cells. ( Brooker, G; Pedone, C, 1986) |
| "Inhibiting protein synthesis by incubating C6-2B rat astrocytoma cells with cycloheximide or emetine for periods up to 24 hours caused a progressive decrease in the accumulation of adenosine 3',5'-monophosphate (cyclic AMP) when the cells were challenged for 30 minutes with 100 microM forskolin." | 3.66 | Selective reduction of forskolin-stimulated cyclic AMP accumulation by inhibitors of protein synthesis. ( Barovsky, K; Brooker, G; Pedone, C, 1983) |
| "As a part of the process of agonist-induced desensitization, 1321N1 human astrocytoma cells lose up to 95% of their beta-adrenergic receptors, as detected by 125I-hydroxybenzylpindolol (125IHYP) binding, after 12-24 h of exposure to isoproterenol." | 3.66 | Recovery of beta-adrenergic receptors following long term exposure of astrocytoma cells to catecholamine. Role of protein synthesis. ( Doss, RC; Harden, TK; Perkins, JP, 1981) |
| "Activation of muscarinic cholinergic receptors on 1321N1 human astrocytoma cells results in a 40-70% inhibition of isoproterenol- or prostaglandin E1 (PGE1)-stimulated accumulation of cyclic AMP." | 3.66 | Muscarinic cholinergic receptor-mediated control of cyclic AMP metabolism. Agonist-induced changes in nucleotide synthesis and degradation. ( Harden, TK; Meeker, RB, 1983) |
| "Incubation of 1321N1 human astrocytoma cells with 1 microM isoproterenol rapidly results in the conversion of a portion of the beta-adrenergic receptors to a membrane form that can be separated from markers for the plasma membrane by sucrose density gradient or differential centrifugation." | 3.66 | Characterization of an altered membrane form of the beta-adrenergic receptor produced during agonist-induced desensitization. ( Harden, TK; Northup, JK; Perkins, JP; Waldo, GL, 1983) |
| "Intracellular cyclic AMP was increased more than 100-fold when rat C6-2B astrocytoma cells were treated with isoproterenol in the cold (4 degrees C)." | 3.66 | Temperature sensitivity of cyclic AMP production and catecholamine-induced refractoriness in a rat astrocytoma cell line. ( Brooker, G; Nickols, GA, 1978) |
| "Incubation of human astrocytoma cells (1321N1) with low concentrations of isoproterenol results in a specific loss of responsiveness to catecholamines as evidenced by a decreased accumulation of cAMP in intact cells, a reduction in isoproterenol-stimulated adenylate cyclase activity, and a decrease in beta-adrenergic receptor density, as measured by the specific binding of 125I-hydroxybenzylpindolol." | 3.66 | Isoproterenol-induced desensitization of adenylate cyclase in human astrocytoma cells. Relation of loss of hormonal responsiveness and decrement in beta-adrenergic receptors. ( Harden, TK; Perkins, JP; Su, YF, 1979) |
| "Incubation of 1321N1 astrocytoma cells for 15 min with 1 microM (-)-isoproterenol resulted in a 50-65% loss of isoproterenol-stimulated adenylate cyclase activity." | 3.66 | Catecholamine-induced desensitization involves an uncoupling of beta-adrenergic receptors and adenylate cyclase. ( Harden, TK; Perkins, JP; Su, YF, 1979) |
| "The characteristics of the effects of catecholamines, prostaglandins, and adenosine on the adenosine 3',5'-monophosphate (cAMP) content of human astrocytoma cells are described." | 3.65 | Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells. ( Clark, RB; Cubeddu, L; Johnson, GL; Ortmann, R; Perkins, JP; Su, YF, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (73.44) | 18.7374 |
| 1990's | 13 (20.31) | 18.2507 |
| 2000's | 4 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goraya, TA | 1 |
| Masada, N | 1 |
| Ciruela, A | 1 |
| Cooper, DM | 2 |
| Toews, ML | 5 |
| Waldo, GL | 5 |
| Harden, TK | 20 |
| Perkins, JP | 20 |
| Doss, RC | 3 |
| Barovsky, K | 4 |
| Brooker, G | 10 |
| Moylan, RD | 1 |
| Meeker, RB | 2 |
| Pedone, C | 3 |
| Mallorga, P | 1 |
| Tallman, JF | 1 |
| Henneberry, RC | 1 |
| Hirata, F | 1 |
| Strittmatter, WT | 1 |
| Axelrod, J | 1 |
| Su, YF | 4 |
| Foster, SJ | 2 |
| Cotton, CU | 1 |
| Lutton, JK | 1 |
| Barrett, PN | 1 |
| Koschel, K | 1 |
| Northup, JK | 1 |
| Frederich, RC | 1 |
| McKenzie, RC | 1 |
| Brophy, PJ | 1 |
| Cadman, ED | 1 |
| Naugles, DD | 1 |
| Lee, CM | 2 |
| Kreps, DM | 1 |
| Whittle, SM | 1 |
| Hoffman, JM | 2 |
| Wu-Wong, JR | 1 |
| Chiou, W | 1 |
| Magnuson, SR | 1 |
| Bianchi, BR | 1 |
| Lin, CW | 1 |
| Hoffman, J | 1 |
| Whittle, S | 1 |
| Toews, M | 1 |
| Wong, MP | 1 |
| Young, KW | 1 |
| Young, JM | 1 |
| Slamon, ND | 1 |
| Pentreath, VW | 1 |
| Zmijewski, JW | 1 |
| Song, L | 1 |
| Harkins, L | 1 |
| Cobbs, CS | 1 |
| Jope, RS | 1 |
| Johnson, GL | 4 |
| Nickols, GA | 2 |
| Clark, RB | 2 |
| Ortmann, R | 3 |
| Cubeddu, L | 1 |
| Gross, RA | 1 |
| Drummond, AH | 1 |
| Baguley, BC | 1 |
| Staehelin, M | 1 |
| Wolfe, BB | 1 |
| Molinoff, PB | 1 |
| Kon, C | 1 |
| Breckenridge, BM | 1 |
| Nutto, D | 1 |
| Waldmeyer, J | 1 |
| Morgan, AJ | 1 |
| Murray, KJ | 1 |
| Challiss, RA | 1 |
| Kurz, JB | 1 |
| Couraud, PO | 2 |
| Durieu-Trautmann, O | 2 |
| Nguyen, DL | 1 |
| Marin, P | 1 |
| Glibert, F | 1 |
| Strosberg, AD | 2 |
| Foignant-Chaverot, N | 1 |
| Johnson, RA | 2 |
| Arneson-Rotert, LJ | 1 |
| Tung, WL | 1 |
| Ruck, A | 1 |
| Millns, P | 1 |
| Kendall, DA | 1 |
| Hill, SJ | 1 |
| Nakahata, N | 1 |
| Abe, MT | 1 |
| Nakanishi, H | 1 |
| Tanner, LI | 1 |
| Wells, JN | 1 |
| Martin, MW | 2 |
| Dal Toso, R | 2 |
| De Bernardi, MA | 3 |
| Costa, E | 3 |
| Mocchetti, I | 3 |
| Balmforth, AJ | 3 |
| Yasunari, K | 2 |
| Vaughan, PF | 3 |
| Ball, SG | 3 |
| Szekely, AM | 1 |
| Alho, H | 1 |
| Smith, AA | 1 |
| Brooker, T | 1 |
| Kramarcy, NR | 1 |
| Masters, SB | 1 |
| Brown, JH | 2 |
| Hertel, C | 2 |
| Coulter, SJ | 2 |
| Freshney, RI | 1 |
| Graham, DI | 1 |
| McNamee, HB | 1 |
| Heng, MM | 1 |
| Gilman, AG | 1 |
| Nirenberg, M | 1 |
64 other studies available for isoproterenol and Astrocytoma
| Article | Year |
|---|---|
Sustained entry of Ca2+ is required to activate Ca2+-calmodulin-dependent phosphodiesterase 1A.
Topics: Adenylyl Cyclases; Astrocytoma; Calcium; Carbachol; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cho | 2004 |
Relationship between an altered membrane form and a low affinity form of the beta-adrenergic receptor occurring during catecholamine-induced desensitization. Evidence for receptor internalization.
Topics: Astrocytoma; Cell Line; Centrifugation, Density Gradient; Concanavalin A; Humans; Isoproterenol; Met | 1984 |
Use of a density shift method to assess beta-adrenergic receptor synthesis during recovery from catecholamine-induced down-regulation in human astrocytoma cells.
Topics: Ascorbic Acid; Astrocytoma; Cell Line; Humans; Iodocyanopindolol; Isoproterenol; Kinetics; Pindolol; | 1984 |
(-)-[125I]-iodopindolol, a new highly selective radioiodinated beta-adrenergic receptor antagonist: measurement of beta-receptors on intact rat astrocytoma cells.
Topics: Adrenergic beta-Antagonists; Animals; Astrocytoma; Binding Sites; Cells, Cultured; Iodine Radioisoto | 1980 |
Agonist-induced changes in beta-adrenergic receptors on intact cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytoma; Binding, Competitive; C | 1984 |
N6,O2'-Dibutyryl cyclic AMP and cholera toxin-induced beta-adrenergic receptor loss in cultured cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytoma; Bucladesine; Cell Line; Cholera Toxin; Isoprotere | 1982 |
Muscarinic cholinergic receptor-mediated activation of phosphodiesterase.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Astro | 1982 |
Selective reduction of forskolin-stimulated cyclic AMP accumulation by inhibitors of protein synthesis.
Topics: Animals; Astrocytoma; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dichlororibofu | 1983 |
Mepacrine blocks beta-adrenergic agonist-induced desensitization in astrocytoma cells.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acids; Astrocytoma; Cells, Cultured; Isoproterenol; Melitten | 1980 |
Catecholamine-specific desensitization of adenylate cyclase. Evidence for a multistep process.
Topics: Adenylyl Cyclases; Animals; Astrocytoma; Catecholamines; Cell Membrane; Enzyme Activation; Epinephri | 1980 |
Dexamethasone increases beta-adrenoceptor density in human astrocytoma cells.
Topics: Adenylyl Cyclases; Astrocytoma; Cells, Cultured; Cycloheximide; Dexamethasone; Humans; Isoproterenol | 1980 |
Catecholamine-induced alteration in sedimentation behavior of membrane bound beta-adrenergic receptors.
Topics: Adenylyl Cyclases; Astrocytoma; Cell Line; Centrifugation, Density Gradient; Concanavalin A; Endocyt | 1980 |
Recovery of beta-adrenergic receptors following long term exposure of astrocytoma cells to catecholamine. Role of protein synthesis.
Topics: Astrocytoma; Cell Line; Cell Membrane; Cycloheximide; Humans; Isoproterenol; Kinetics; Neoplasm Prot | 1981 |
Muscarinic cholinergic receptor-mediated control of cyclic AMP metabolism. Agonist-induced changes in nucleotide synthesis and degradation.
Topics: Alprostadil; Astrocytoma; Carbachol; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Humans | 1983 |
Effect of antibody-induced modulation of measles (SSPE) virus membrane proteins on beta-adrenergic receptor-mediated adenylate cyclase activity.
Topics: Adenylyl Cyclases; Animals; Antigens, Viral; Astrocytoma; Cell Line; Cell Membrane; Cyclic AMP; Immu | 1983 |
Characterization of an altered membrane form of the beta-adrenergic receptor produced during agonist-induced desensitization.
Topics: Adenylyl Cyclases; Astrocytoma; Cell Line; Cell Membrane; Humans; Isoproterenol; Molecular Weight; P | 1983 |
Characterization of agonist-induced beta-adrenergic receptor-specific desensitization in C62B glioma cells.
Topics: Adenylyl Cyclases; Animals; Astrocytoma; Catecholamines; Cells, Cultured; Centrifugation, Density Gr | 1983 |
Isoproterenol stimulates lipid methylation in C6 cells without affecting membrane fluidity.
Topics: Animals; Astrocytoma; Cyclic AMP; Electron Spin Resonance Spectroscopy; Isoproterenol; Lipid Metabol | 1983 |
Distinct mechanisms of forskolin-stimulated cyclic AMP accumulation and forskolin-potentiated hormone responses in C6-2B cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Astrocytoma; Cells, Cultured; Cholera Toxin; Colforsin; Cyc | 1984 |
cAMP is not involved in interleukin-1-induced interleukin-6 release from human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Astrocytoma; Bucladesine; Colforsin; Cyclic AMP; Hum | 1994 |
Lysophosphatidic acid mimics serum-induced sensitization of cyclic AMP accumulation.
Topics: Alprostadil; Animals; Astrocytoma; Blood; Colforsin; Cyclic AMP; Drug Interactions; Glioma; Humans; | 1993 |
Human astrocytoma U138MG cells express predominantly type-A endothelin receptor.
Topics: Astrocytoma; Base Sequence; Binding, Competitive; Cell Membrane; Colforsin; Cyclic AMP; DNA Primers; | 1996 |
Modulation of cyclic AMP accumulation in glial cells by exogenous phospholipase C.
Topics: Adenylate Cyclase Toxin; Astrocytoma; Colforsin; Cyclic AMP; Down-Regulation; Glioma; Humans; Isopro | 1996 |
Characteristics of the Ca(2+)-dependent inhibition of cyclic AMP accumulation by histamine and thapsigargin in human U373 MG astrocytoma cells.
Topics: Adenylyl Cyclase Inhibitors; Astrocytoma; Calcium; Cyclic AMP; Enzyme Inhibitors; Histamine; Humans; | 2000 |
Antioxidant defense against antidepressants in C6 and 1321N1 cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Antidepressive Agents; Antimetabolit | 2000 |
Second messengers regulate RGS2 expression which is targeted to the nucleus.
Topics: Astrocytoma; Blotting, Western; Carbachol; Cell Membrane; Cell Nucleus; Colforsin; Cyclic AMP; Cytos | 2001 |
Drug-induced modification of the responsiveness of adenylate cyclase to hormones.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Astrocytoma; Catecholamines; Cholera Toxin; Drug Int | 1978 |
Temperature sensitivity of cyclic AMP production and catecholamine-induced refractoriness in a rat astrocytoma cell line.
Topics: 1-Methyl-3-isobutylxanthine; Astrocytoma; Cell Line; Cyclic AMP; Isoproterenol; Kinetics; Temperatur | 1978 |
Induction of refractoriness to isoproterenol by prior treatment of C6-2B rat astrocytoma cells with cholera toxin.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Astrocytoma; Cell Line; Cholera Toxin; Cycl | 1979 |
Factors influencing the effect of hormones on the accumulation of cyclic AMP in cultured human astrocytoma cells.
Topics: Adenine; Adenosine; Adenosine Monophosphate; Astrocytoma; Catecholamines; Cells, Cultured; Cyclic AM | 1975 |
Regulation of adenosine 3',5'-monophosphate content in human astrocytoma cells by isoproterenol and carbachol.
Topics: Adenosine; Ascorbic Acid; Astrocytoma; Calcium; Carbachol; Cell Line; Cyclic AMP; Drug Interactions; | 1977 |
Stimulation of adenosine 3':5'-monophosphate formation by prostaglandins in human astrocytoma cells. Inhibition by nonsteroidal anti-inflammatory agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Astrocytoma; Cell Line; Cyclic AMP; Isoproterenol; Kinetics | 1977 |
Beta adrenergic regulation of glycogen phosphorylase activity and adenosine cyclic 3', 5'-monophosphate accumulation in control and desensitized C-6 astrocytoma cells.
Topics: Animals; Astrocytoma; Calcimycin; Cells, Cultured; Cyclic AMP; Isoproterenol; Neoplasm Proteins; Pho | 1977 |
Regulation of adenosine 3':5'-monophosphate content of rous sarcoma virus-transformed human astrocytoma cells. Effects of cholera toxin on the responsiveness to catecholamines and prostaglandins.
Topics: Adenylyl Cyclases; Astrocytoma; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Viral; Choler | 1978 |
Role of beta-adrenergic receptors in catecholamine-induced desensitization of adenylate cyclase in human astrocytoma cells.
Topics: Adenylyl Cyclases; Astrocytoma; Cell Line; Cyclic AMP; Humans; Isoproterenol; Kinetics; Propranolol; | 1978 |
Isoproterenol-induced desensitization of adenylate cyclase in human astrocytoma cells. Relation of loss of hormonal responsiveness and decrement in beta-adrenergic receptors.
Topics: Adenylyl Cyclases; Astrocytoma; Cell Line; Cell Membrane; Cyclic AMP; Humans; Isoproterenol; Kinetic | 1979 |
Differential expression of components of the adenylate cyclase system during growth of astrocytoma cells in culture.
Topics: Adenylyl Cyclases; Animals; Astrocytoma; Cell Division; Cell Line; Humans; Isoproterenol; Kinetics; | 1979 |
Potentiation of guanosine 3':5'-monophosphate accumulation in C-6 glial tumor cells.
Topics: Adenylyl Cyclases; Astrocytes; Astrocytoma; Azides; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Isop | 1979 |
Catecholamine-induced desensitization involves an uncoupling of beta-adrenergic receptors and adenylate cyclase.
Topics: Adenylyl Cyclases; Astrocytoma; Benzyl Alcohols; Binding Sites; Cell Line; Dose-Response Relationshi | 1979 |
Phloretin and related compounds inhibit agonist stimulated cAMP accumulation in cultured cells of CNS origin.
Topics: Adenosine; Animals; Astrocytoma; Cells, Cultured; Central Nervous System; Cyclic AMP; Glycosides; Hu | 1979 |
Comparison of methods to assess cyclic AMP turnover under conditions of agonist stimulation in 1321N1 astrocytoma cells.
Topics: Adenine; Adenosine Triphosphate; Animals; Astrocytoma; Carbon Radioisotopes; Cell Line; Cyclic AMP; | 1992 |
Isoproterenol-initiated beta-adrenergic receptor diacytosis in cultured cells.
Topics: Adrenergic beta-Antagonists; Astrocytoma; Cell Membrane; Half-Life; Humans; Iodine Radioisotopes; Is | 1992 |
Functional endothelin-1 receptors in rat astrocytoma C6.
Topics: Animals; Aorta; Astrocytoma; Cell Membrane; Colforsin; Cyclic AMP; DNA, Neoplasm; Endothelins; Inosi | 1991 |
cAMP-dependent down-regulation of endothelin-1 receptors on rat astrocytoma C6 cells.
Topics: Animals; Astrocytoma; Bucladesine; Colforsin; Cyclic AMP; Down-Regulation; Endothelins; Iodine Radio | 1991 |
Protein kinase C activators sensitize cyclic AMP accumulation by intact 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Astrocytoma; Carbachol; Colforsin; Cyclic AMP; | 1990 |
Serum-induced sensitization of cyclic AMP accumulation in 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Astrocytoma; Blo | 1991 |
Effects of tachykinins on [3H]taurine release from human astrocytoma cells (U-373 MG).
Topics: Astrocytoma; Cell Line; Cyclic AMP; Humans; Isoproterenol; Kinetics; Neurokinin A; Substance P; Tach | 1991 |
Expression of beta 2-adrenoceptors mediating cyclic AMP accumulation in astroglial and neuronal cell lines derived from the rat CNS.
Topics: Animals; Astrocytoma; Cell Line; Central Nervous System; Cyclic AMP; Isoproterenol; Neurons; Norepin | 1990 |
PGJ2 and delta 12PGJ2 inhibit cell growth accompanied with inhibition of phosphoinositide turnover in human astrocytoma cells.
Topics: Astrocytoma; Carbachol; Cell Division; Cyclic AMP; DNA; GTP-Binding Proteins; Histamine; Humans; Ino | 1990 |
Identification of the phosphodiesterase regulated by muscarinic cholinergic receptors of 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Astrocytoma; Calcium; Carba | 1986 |
Beta adrenergic and prostaglandin receptor activation increases nerve growth factor mRNA content in C6-2B rat astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Astrocytoma; Cell Line; Isoproterenol; Male; Mice | 1988 |
Characterization of dopamine and beta-adrenergic receptors linked to cyclic AMP formation in intact cells of the clone D384 derived from a human astrocytoma.
Topics: 1-Methyl-3-isobutylxanthine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic | 1988 |
Glucocorticoids modify differentially dopamine- and prostaglandin E1-mediated cyclic AMP formation by the cultured human astrocytoma clone D384.
Topics: Adenylyl Cyclases; Alprostadil; Astrocytoma; Colforsin; Cyclic AMP; Cycloheximide; Dexamethasone; Do | 1989 |
Regulation of nerve growth factor biosynthesis by beta-adrenergic receptor activation in astrocytoma cells: a potential role of c-Fos protein.
Topics: 2-Aminopurine; Animals; Astrocytoma; Blotting, Northern; Cyclic AMP; Cycloheximide; Gene Expression | 1989 |
Expression of rat mRNA coding for hormone-stimulated adenylate cyclase in Xenopus oocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Astrocytoma; Cell Membrane; Colf | 1987 |
Beta-adrenergic receptor regulation of NGF-mRNA content in rat C6-2B glioma cells.
Topics: Animals; Astrocytoma; Glioma; Isoproterenol; Nerve Growth Factors; Rats; Receptors, Adrenergic, beta | 1987 |
Effects of tunicamycin on the expression of beta-adrenergic receptors in human astrocytoma cells during growth and recovery from agonist-induced down-regulation.
Topics: Astrocytoma; Cell Count; Cells, Cultured; Cycloheximide; Glucosamine; Humans; Isoproterenol; Recepto | 1985 |
Pertussis toxin does not inhibit muscarinic-receptor-mediated phosphoinositide hydrolysis or calcium mobilization.
Topics: Animals; Astrocytoma; Calcium; Carbachol; Cells, Cultured; Chick Embryo; GTP-Binding Proteins; Heart | 1985 |
A comparison of catecholamine-induced internalization of beta-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells. Inhibition by phenylarsine oxide.
Topics: Adenosine Triphosphate; Arsenicals; Astrocytoma; Catecholamines; Cell Line; Dithiothreitol; Endocyto | 1985 |
The involvement of cellular ATP in receptor-mediated internalization of epidermal growth factor and hormone-induced internalization of beta-adrenergic receptors.
Topics: Adenosine Triphosphate; Antimycin A; Astrocytoma; Binding, Competitive; Cell Line; Deoxyglucose; End | 1986 |
D-1 dopaminergic and beta-adrenergic stimulation of adenylate cyclase in a clone derived from the human astrocytoma cell line G-CCM.
Topics: Adenylyl Cyclases; Astrocytoma; Cell Line; Clone Cells; Cyclic AMP; Dopamine; Flupenthixol; Humans; | 1986 |
Receptor reserve in the calcium-dependent cyclic AMP response of astrocytoma cells to muscarinic receptor stimulation: demonstration by agonist-induced desensitization, receptor inactivation, and phorbol ester treatment.
Topics: Astrocytoma; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; Inositol Phosphates; Isoproterenol; Ox | 1986 |
Maintenance of whole cell isoproterenol and forskolin responsiveness in adenylate cyclase of permeabilized cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Astrocytoma; Cell Line; Cell Membrane Permeabili | 1986 |
Effect of catecholamines on the adenosine 3':5'-cyclic monophosphate concentrations of clonal satellite cells of neurons.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aminobutyrates; Animals; Astrocytoma; Car | 1971 |