Page last updated: 2024-10-29

isoproterenol and Anesthesia

isoproterenol has been researched along with Anesthesia in 189 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"Urethane produces a level of surgical anesthesia characterized by preservation of a number of cardiovascular reflexes."8.77Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2: Cardiovascular system. ( Maggi, CA; Meli, A, 1986)
"Effects of Saiko-ka-ryukotsu-borei-to (SRBT) on theophylline-induced tachycardia in anesthetized rats and theophylline-induced locomotion and convulsions in mice were examined."7.70Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice. ( Chisaki, K; Hayashi, H; Komatsu, Y; Sanae, F, 1999)
"The isoproterenol-mediated increase in NE release is inhibited by halothane anesthesia, indicating that halothane inhibits prejunctional beta 2-adrenergic receptor regulation of NE release."7.69Regulation of norepinephrine release by beta 2-adrenergic receptors during halothane anesthesia. ( Deegan, R; He, HB; Krivoruk, Y; Wood, AJ; Wood, M, 1995)
" Flosequinan, milrinone, isoprenaline and forskolin given intravenously at similarly hypotensive doses have been evaluated in separate studies for their effect on ischaemia-induced arrhythmias and on ventricular cyclic nucleotide content following coronary artery ligation in the pentobarbitone anaesthetized rat."7.68Effect of flosequinan on ischaemia-induced arrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat. ( Dickinson, K; Foster, GA; Frodsham, G; Jones, RB, 1993)
"Isoproterenol (ISO), is a non-selective beta-adrenergic agonist, that is used widely to induce cardiac injury in mice."5.51Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice. ( Chang, S; Mandelli, A; Ren, S; Tran, A; Wang, JJ; Wang, Y, 2019)
"Cetamolol was able to block epinephrine-induced hypokalemia completely, in a dose-related manner, and to block isoproterenol-induced hypokalemia partially."5.28Comparison of the effects of cetamolol and atenolol on epinephrine- and isoproterenol-induced hypokalemia in anesthetized dogs. ( Klein, M; Nettler, S; Oshiro, G; Smith, T; Stupienski, RF, 1989)
" We have constructed isoproterenol dose-response curves in four groups of patients under general anesthesia: group I, 27 elderly normotensive patients not receiving drugs; group II, 14 hypertensive patients treated with cardioselective beta-adrenoceptor antagonists; group III, 15 hypertensive patients receiving nonselective beta-adrenoceptor antagonists; group IV, 13 patients receiving an infusion of labetalol at 0."5.27Assessment of beta-adrenoceptor blockade during anesthesia in humans: use of isoproterenol dose-response curves. ( Dagnino, J; Prys-Roberts, C, 1985)
"We found that during sevoflurane anesthesia in children, a heart rate increase > or = 10 bpm and a systolic blood pressure increase > or = 15 mm Hg, when preceded by atropine, may be reliable indicators for detecting intravascular injection."5.08Simulation of an epidural test dose with intravenous epinephrine in sevoflurane-anesthetized children. ( Nishikawa, T; Tanaka, M, 1998)
"Urethane produces a level of surgical anesthesia characterized by preservation of a number of cardiovascular reflexes."4.77Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2: Cardiovascular system. ( Maggi, CA; Meli, A, 1986)
"In order to determine the role of the adrenergic system in bupivacaine-induced cardiotoxicity, a series of experiments were performed."3.88Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication. ( Chen, Y; Cheng, Y; Chu, L; Duan, R; Li, H; Li, J; Xia, D; Yuan, J; Zhang, J; Zhang, Y; Zhao, S; Zhao, X, 2018)
" Here, we investigated the systemic and coronary arterial responses of five anesthetized juvenile American alligators (Alligator mississippiensis) to hypoxia, acetylcholine, adenosine, sodium nitroprusside, isoproterenol, and phenylephrine."3.83Coronary blood flow in the anesthetized American alligator (Alligator mississippiensis). ( Crossley, DA; Elfwing, M; Elsey, RM; Jensen, B; Wang, T, 2016)
" We report a case of severe bradycardia associated with anaphylactic shock after aprotinin in a beta-blocked child, which was resistant to intravenous epinephrine and vascular filling but was treated successfully with isoproterenol."3.74Anaphylactic shock in a beta-blocked child: usefulness of isoproterenol. ( Baele, P; Brui, B; Matta, A; Momeni, M, 2007)
"Effects of Saiko-ka-ryukotsu-borei-to (SRBT) on theophylline-induced tachycardia in anesthetized rats and theophylline-induced locomotion and convulsions in mice were examined."3.70Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice. ( Chisaki, K; Hayashi, H; Komatsu, Y; Sanae, F, 1999)
"The isoproterenol-mediated increase in NE release is inhibited by halothane anesthesia, indicating that halothane inhibits prejunctional beta 2-adrenergic receptor regulation of NE release."3.69Regulation of norepinephrine release by beta 2-adrenergic receptors during halothane anesthesia. ( Deegan, R; He, HB; Krivoruk, Y; Wood, AJ; Wood, M, 1995)
" Flosequinan, milrinone, isoprenaline and forskolin given intravenously at similarly hypotensive doses have been evaluated in separate studies for their effect on ischaemia-induced arrhythmias and on ventricular cyclic nucleotide content following coronary artery ligation in the pentobarbitone anaesthetized rat."3.68Effect of flosequinan on ischaemia-induced arrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat. ( Dickinson, K; Foster, GA; Frodsham, G; Jones, RB, 1993)
" A significant reversal of cardiac failure was attained in anaesthetised dogs subjected to propranolol induced cardiac insufficiency."3.68Cardiotonic activity of the water soluble forskolin derivative 8,13-epoxy-6 beta-(piperidinoacetoxy)- 1 alpha, 7 beta, 9 alpha-trihydroxy-labd- 14en-11-one. ( Ghate, AV; Linz, W; Rajagopalan, R; Schoelkens, BA; Subbarayan, P, 1993)
" propranolol (Prop) produced sustained pressor responses in rats but not in dogs under urethane anesthesia."3.67Different responses to beta-adrenoceptor blocking drugs of the blood pressure and heart rate in the urethane-anesthetized dog and rat. ( Himori, N; Ishimori, T, 1988)
" Therefore, we sought to clarify the role of beta-adrenergic receptor activity in carotid body function by assessing: the ventilatory response to intravenous isoproterenol infusion in awake and anesthetized carotid body intact and carotid body denervated goats, the effect of propranolol on the ventilatory response to isocapnic hypoxemia, and carotid sinus nerve chemoreceptor discharge rate response to isoproterenol and hypoxia."3.67Role of beta adrenergic receptors in carotid body function of the goat. ( Bisgard, GE; Hudgel, DW; Kressin, NA; Nielsen, AM, 1986)
" We measured arterial and venous plasma DOPA concentrations in healthy subjects at rest, patients who had undergone regional sympathectomies or were undergoing general anesthesia, and subjects during procedures (tilt, oral clonidine, or iv isoproterenol, yohimbine, trimethaphan, or diazepam) known to affect plasma norepinephrine levels."3.67Neuronal source of plasma dihydroxyphenylalanine. ( Eisenhofer, G; Goldstein, DS; Keiser, HR; Kopin, IJ; Stull, R; Udelsman, R, 1987)
" Under pentobarbital anesthesia, the bronchodilating activity of l-MTI was approx."3.66[Bronchodilating action of (--)-1-(3, 4, 5-trimethoxybenzyl)-7-hydroxy-1, 2, 3, 4-tetrahydroisoquinoloine HCl (l-MTI) (author's transl)]. ( Ikezawa, K; Irie, K; Kiyomoto, A; Nakajima, H; Sato, M; Takenaga, H, 1978)
"Isoproterenol (ISO), is a non-selective beta-adrenergic agonist, that is used widely to induce cardiac injury in mice."1.51Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice. ( Chang, S; Mandelli, A; Ren, S; Tran, A; Wang, JJ; Wang, Y, 2019)
"A novel class of biphenyl analogues containing a benzoic acid moiety based on lead compound 8i have been identified as potent and selective human beta 3 adrenergic receptor (beta 3-AR) agonists with good oral bioavailability and long plasma half-life."1.35Discovery of a novel series of biphenyl benzoic acid derivatives as potent and selective human beta3-adrenergic receptor agonists with good oral bioavailability. Part I. ( Hamada, K; Hamashima, H; Hattori, K; Imamura, E; Imanishi, M; Ishikawa, H; Itou, S; Matsui, S; Matsumura, Y; Nakajima, Y; Nakano, K; Sakurai, M; Takamura, F; Tomishima, Y; Ueshima, K; Unami, N; Washizuka, K; Yamamoto, N; Yamamoto, T, 2008)
" In a further 10 pigs, dose-response curves were obtained by graded increases in the infused dose of hormone between 0."1.32The effect of dehydroepiandrosterone on regional blood flow in prepubertal anaesthetized pigs. ( Battaglia, A; Grossini, E; Mary, DA; Molinari, C; Vacca, G; Vassanelli, C, 2004)
"Ventricular arrhythmias were evaluated as ventricular premature beats (VPBs), tachycardiac (VT) episodes and the incidences of VT and ventricular fibrillation (VF) during occlusion and following reperfusion."1.31Noradrenaline, infused locally, reduces arrhythmia severity during coronary artery occlusion in anaesthetised dogs. ( Parratt, JR; Végh, A, 2002)
" Atenolol displaced the dose-response curve to ICI 170777 to the right by 4 fold but displaced the isoprenaline dose-response curve to the right by 247 fold."1.28The cardiovascular pharmacology of ICI 170777 ((6RS)-6-methyl-5-(pyrid-4-yl)-3H,6H-1,3,4- thiadiazin-2-one) a novel compound with positive inotropic and vasodilator effects. ( Collis, MG; Keddie, JR; Rouse, W, 1989)
"Xamoterol is a partial beta 1-adrenergic agonist that has combined beta 1-stimulating and beta 1-blocking actions."1.28Effects of the partial beta 1-adrenergic agonist, xamoterol, on hemodynamics and regional myocardial function during acute coronary occlusion in dogs. ( Katayama, K; Kohno, M; Kumada, T; Kusukawa, R; Matsuzaki, M; Miura, T; Ozaki, M; Toma, Y; Yonezawa, F, 1990)
"Atenolol abolished the increase in HR by isoproterenol but did not affect the increases in coronary and muscular arterial conductances."1.28Effects of beta 1- and beta 2-adrenoceptor stimulation on hemodynamics in the anesthetized rat. ( Abdelrahman, A; Pang, CC; Tabrizchi, R, 1990)
"Cetamolol was able to block epinephrine-induced hypokalemia completely, in a dose-related manner, and to block isoproterenol-induced hypokalemia partially."1.28Comparison of the effects of cetamolol and atenolol on epinephrine- and isoproterenol-induced hypokalemia in anesthetized dogs. ( Klein, M; Nettler, S; Oshiro, G; Smith, T; Stupienski, RF, 1989)
"Isoproterenol (ISO) was administered as bolus injections before (0."1.28Beta-adrenoceptor blocking activity of diprafenone in anesthetized dogs: comparison with propafenone and propranolol. ( Cantor, E; Greenberg, S; Paul, J, 1989)
" Furthermore, in the pithed rat, the alpha 1-adrenoceptor-mediated pressor dose-response curve to cirazoline was shifted approximately 6-fold to the right by both the (+)-R- and (-)-S-enantiomers of carvedilol at a dose of 1 mg/kg, i."1.28The interaction of the enantiomers of carvedilol with alpha 1- and beta 1-adrenoceptors. ( Ashton, DJ; Hieble, JP; Nichols, AJ; Ruffolo, RR; Sulpizio, AC, 1989)
"Bisoprolol was about 2 times more effective in suppressing isoprenaline-induced increases in LVdP/dtmax than those in heart rate."1.27Bisoprolol improves perfusion of ischaemic myocardium in anaesthetized pigs. ( den Boer, MO; Rensen, RJ; Sassen, LM; Saxena, PR; Verdouw, PD, 1988)
" Dose-response curves were determined for either isoproterenol or dobutamine 30 min after treatment with hexamethonium (20mg/kg)."1.27Role of alpha-adrenergic receptors in the intrinsic inotropic selectivity of dobutamine in anesthetized dogs. ( Gorczynski, RJ; Shaffer, JE, 1985)
" We have constructed isoproterenol dose-response curves in four groups of patients under general anesthesia: group I, 27 elderly normotensive patients not receiving drugs; group II, 14 hypertensive patients treated with cardioselective beta-adrenoceptor antagonists; group III, 15 hypertensive patients receiving nonselective beta-adrenoceptor antagonists; group IV, 13 patients receiving an infusion of labetalol at 0."1.27Assessment of beta-adrenoceptor blockade during anesthesia in humans: use of isoproterenol dose-response curves. ( Dagnino, J; Prys-Roberts, C, 1985)
"The influence of different baseline values (blood pressure, heart rate) on ED50- and Emax-values of isoprenaline dose-response curves (DRC) in the presence and absence of beta-blocking drugs was assessed in urethane-anesthetized rats."1.27Assessment of adrenergic beta-blockade in the anesthetized rat at different baseline values. ( Brunner, F; Pöch, G, 1984)
"Amitraz was then tested on spontaneously beating guinea-pig isolated atria."1.27The cardiac effects of amitraz in the guinea-pig in vivo and in vitro. ( Pascoe, AL; Reynoldson, JA, 1986)
"Exaprolol also has direct electrophysiological effects on cardiac (Purkinje) tissue, reducing the rate of rise of phase 0 of the action potential."1.27Aspects of the cardiovascular pharmacology of exaprolol. ( Hughes, B; Kane, KA; McDonald, FM; Parratt, JR, 1984)
"Effects of chronic administration of denopamine on acute cardiovascular response to denopamine were studied in anesthetized rats."1.27Effect of chronic administration of denopamine (TA-064), a new positive inotropic agent, on cardiac response of rats to denopamine. ( Nagao, T; Naito, K; Yabana, H, 1986)
"Phenoxybenzamine was found to have antivagal actions which might account for some of the delayed cardiac acceleration."1.25Hemodynamic effects of phenoxybenzamine in anesthetized dogs. ( Fowler, NO; Gaffney, TE; Grupp, G; Holmes, JC; Privitera, PJ, 1970)

Research

Studies (189)

TimeframeStudies, this research(%)All Research%
pre-1990129 (68.25)18.7374
1990's37 (19.58)18.2507
2000's19 (10.05)29.6817
2010's4 (2.12)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Imanishi, M1
Tomishima, Y1
Itou, S1
Hamashima, H1
Nakajima, Y1
Washizuka, K1
Sakurai, M1
Matsui, S1
Imamura, E1
Ueshima, K1
Yamamoto, T1
Yamamoto, N1
Ishikawa, H1
Nakano, K1
Unami, N1
Hamada, K1
Matsumura, Y1
Takamura, F1
Hattori, K1
Ren, S1
Chang, S1
Tran, A1
Mandelli, A1
Wang, Y1
Wang, JJ1
Li, J1
Duan, R1
Zhang, Y1
Zhao, X1
Cheng, Y1
Chen, Y1
Yuan, J1
Li, H1
Zhang, J1
Chu, L1
Xia, D1
Zhao, S1
Jensen, B1
Elfwing, M1
Elsey, RM1
Wang, T1
Crossley, DA1
Yin, W1
Liu, JC1
Fan, R1
Sun, XQ1
Ma, J1
Feng, N1
Zhang, QY1
Yin, Z1
Zhang, SM1
Guo, HT1
Bi, H1
Wang, YM1
Sun, X1
Cheng, L1
Cui, Q1
Yu, SQ1
Yi, DH1
Pei, JM1
Lamhaut, L1
Mantz, B1
Vivien, B1
Schwarz, PB1
Yee, N1
Mir, S1
Peever, JH1
Chen, F1
Kan, H1
Hobbs, G1
Finkel, MS1
Kasture, AV1
Shingvekar, DS1
Dorle, AK1
Zhou, J1
Luan, GD1
Ren, LM1
Wu, ZG1
Wang, X1
Zhao, Y1
Crystal, GJ1
Salem, MR1
Knollmann, BC1
Kirchhof, P1
Sirenko, SG1
Degen, H1
Greene, AE1
Schober, T1
Mackow, JC1
Fabritz, L1
Potter, JD1
Morad, M1
Brooks, WW1
Conrad, CH1
Nedder, AP1
Bing, OH1
Slawsky, MT1
DARBY, TD1
SPROUSE, JH1
WALTON, RP1
LINTON, S1
ODELL, JR1
ANKERMANN, H1
HUKOVIC, S1
MUSCHOLL, E1
GOLD, MI1
BENNIKE, KA1
HAGELSTEN, JO1
GRIMMEISEN, H2
TAKAORI, M1
LOEHNING, RW1
Molinari, C2
Battaglia, A1
Grossini, E2
Mary, DA2
Vassanelli, C1
Vacca, G2
Uberti, F1
Ghigo, E1
Ribichini, F1
Surico, N1
Momeni, M1
Brui, B1
Baele, P1
Matta, A1
Levy, B2
Peres-Polon, VL1
Corrêa, FM1
Boucher, M1
Dubray, C1
Duchene-Marullaz, P1
McPherson, GA1
Malta, E3
Raper, C3
Campbell, CA1
Parratt, JR4
Brunner, F1
Pöch, G1
Beaulieu, G1
Grimes, D1
Muirhead, C1
Oshiro, G2
Hughes, B1
Kane, KA2
McDonald, FM1
Hashimoto, H1
Asano, M1
Hayashi, T1
Oguro, K1
Takiguchi, Y1
Nakashima, M1
Merican, Z1
Nott, MW1
Suzuki, M1
Satoh, S1
Ikeda, S1
Tamaoki, H1
Akahane, M4
Nebashi, Y1
Seitelberger, R1
Raberger, G1
Maccarrone, C1
Seaman, KL1
Greenway, CV1
Strubelt, O2
Nishimura, H1
Nakamura, Y1
Sumner, RP1
Khosla, MC1
Hayes, JS1
Diederen, W1
Weisenberger, H1
Okazaki, K1
Yamada, Y1
Tomino, T1
Day, MD2
Poyser, RH1
Sempik, J2
Tsuchiya, M1
Walsh, GM1
Ferrone, RA1
Ishise, S1
Frohlich, ED1
Avendano, CE1
Billman, GE1
Yamazaki, J1
Sugimoto, T1
Yabana, H3
Nagao, T4
Mazzoni, L1
Naef, R1
Chapman, ID1
Morley, J1
Hodeige, D1
Heyndrickx, JP1
Chatelain, P1
Manning, A1
García, JL1
Fernandez, N1
Garcia-Villalon, AL1
Monge, L1
Gomez, B1
Dieguez, G1
Hara, Y1
Sugimoto, S1
Ono, H1
Deegan, R1
He, HB1
Krivoruk, Y1
Wood, AJ1
Wood, M1
Takahashi, H1
Nakamura, S1
Shirahase, H1
Yoshida, T1
Nishimura, M1
Yoshimura, M1
Jones, RB1
Frodsham, G1
Dickinson, K1
Foster, GA1
Murata, S1
Narita, H1
Shimizu, R1
Miyagishima, T1
Takeda, M1
Rajagopalan, R1
Ghate, AV1
Subbarayan, P1
Linz, W1
Schoelkens, BA1
Lai, CJ1
Kou, YR1
Tanaka, M3
Nishikawa, T3
Whalen, EJ1
Johnson, AK1
Lewis, SJ1
Sanae, F1
Hayashi, H1
Chisaki, K1
Komatsu, Y2
Huang, YC1
Wu, BN1
Lin, YT1
Chen, SJ1
Chiu, CC1
Cheng, CJ1
Chen, IJ1
Sugiyama, A1
Takahara, A1
Hashimoto, K1
Hamase, K1
Homma, H1
Takigawa, Y1
Imai, K1
Murakami, M2
Tomiyama, Y2
Hayakawa, K1
Ajisawa, Y2
Park, YC2
Ohnishi, N1
Sugiyama, T1
Kurita, T2
Kimura, T1
Goyagi, T1
Ogasawara, K1
Nitta, R1
Takeda, H2
Igawa, Y2
Yamazaki, Y2
Nishizawa, O2
Miyatake, R1
Rouleau, JR1
Dagnault, A1
Simard, D1
Lavallée, B1
Bélanger, A1
Blouin, A1
Kingma, JG1
Mastronardi, CA1
Yu, WH1
Srivastava, VK1
Dees, WL1
McCann, SM1
Akahane, S1
Miyata, H1
Végh, A1
Yamashita, S1
Takai, M1
Yabuuchi, Y1
Lundgren, B1
Carlsson, E1
Herrmann, I1
Ikezawa, K2
Takenaga, H2
Irie, K1
Sato, M2
Nakajima, H2
Kiyomoto, A2
Van Den Brenk, HA1
Stone, MG1
Kelly, H1
Sharpington, C1
Vatner, SF1
Marsh, JD1
Swain, JA1
Pendleton, RG1
Finlay, E1
Sherman, S1
Mueller, RA1
Yin, FC1
Spurgeon, HA1
Greene, HL1
Lakatta, EG1
Weisfeldt, ML1
Reilly, FD1
McCuskey, RS1
Yun, JC1
Kelly, GD1
Bartter, FC1
Tate, JE1
Greenwald, SE1
Newman, DL1
Bowden, NL1
Walldius, G1
Saito, T1
Strashnov, VI1
Tuleutaev, TB1
Barch, GK1
Talbott, MW1
Martín, N1
Bardisa, L1
Pantoja, C1
Román, R1
Vargas, M1
Lee, KC1
Canniff, PC1
Hamel, DW1
Pagani, ED1
Ezrin, AM1
Miura, T1
Matsuzaki, M1
Toma, Y1
Yonezawa, F1
Kohno, M1
Katayama, K1
Ozaki, M1
Kumada, T1
Kusukawa, R1
Abdelrahman, A1
Tabrizchi, R1
Pang, CC1
Noguchi, K1
Kato, T1
Kinjo, N1
Moromizato, H1
Sakanashi, M1
Dowell, RT1
Park, KW1
Lowenstein, E1
Colbert, WE1
Turk, JA1
Williams, PD1
Buening, MK1
Eden, RJ1
Wallduck, MS1
Patel, B1
Owen, DA1
den Boer, MO3
Sassen, LM2
van der Giessen, WJ1
Saxena, PR3
Verdouw, PD2
Halbrügge, T1
Friedgen, B1
Thyen, A1
Graefe, KH1
Withrington, PG2
Dhume, VG1
Croxton, R1
Gerbes, AL1
Roquebert, J1
Alaoui, K1
Morán Benito, A1
Potter, DE1
Crosson, CE1
Heath, AR1
Ogidigben, MJ1
Villalón, CM1
Heiligers, JP1
Rigel, DF1
Lathrop, DA1
Gorodetskaya, EA1
Dugin, SF1
Golikov, MA1
Kapelko, VI1
Medvedev, OS1
Bomzon, A1
Monies-Chass, I1
Kamenetz, L1
Blendis, L1
Nakahara, H1
Nakazawa, M1
Tsukada, T1
Imai, S1
Williams, FM1
Rochette, L1
Van de Water, A1
Janssens, W1
Van Neuten, J1
Xhonneux, R1
De Cree, J1
Verhaegen, H1
Reneman, RS1
Janssen, PA1
Klein, M1
Stupienski, RF1
Nettler, S1
Smith, T1
Greenberg, S1
Cantor, E1
Paul, J1
Kazanietz, MG1
Gutkind, JS1
Puyo, A1
Armando, I1
Enero, MA1
Chess-Williams, R1
Coker, SJ1
Hadfield, SE1
Slee, SJ1
Snow, HM1
Nichols, AJ1
Sulpizio, AC1
Ashton, DJ1
Hieble, JP1
Ruffolo, RR1
Collis, MG1
Keddie, JR1
Rouse, W1
Foucart, S1
Nadeau, R1
de Champlain, J1
Probst, A1
Lill, H1
Strein, K1
Dagnino, J1
Prys-Roberts, C2
Tsushima, H1
Mori, M1
Matsuda, T1
Pascoe, AL1
Reynoldson, JA1
Beckmann, R1
Müller, B1
Schröder, G1
Stock, G1
Dunlap, ED1
Samols, E1
Waite, LC1
Pfeifer, MA1
Rankin, AJ1
Wilson, N1
Ledsome, JR1
Holloway, RH1
Blank, EL1
Takahashi, I1
Dodds, WJ1
Dent, J1
Sarna, SK1
Cambridge, D1
Whiting, MV1
Allan, G1
Himori, N1
Ishimori, T1
Rensen, RJ1
Mian, MA1
Abdel-Rahman, AR1
Ingenito, AJ1
Shaffer, JE1
Gorczynski, RJ1
Maggi, CA1
Meli, A1
Hudgel, DW1
Kressin, NA1
Nielsen, AM1
Bisgard, GE1
Schliep, HJ1
Schulze, E1
Harting, J1
Haeusler, G1
Goldstein, DS1
Udelsman, R1
Eisenhofer, G1
Stull, R1
Keiser, HR1
Kopin, IJ1
Drake, DH1
McClanahan, TB1
Ning, XH1
Gerren, RA1
Dunham, WR1
Gallagher, KP1
Vidrio, H1
García-Márquez, F1
Seyde, WC1
Stephan, H1
Rieke, H1
Eriksson, P1
Boman, K1
Jacobsson, B1
Olofsson, BO1
Naito, K1
Salvati, P1
Bianchi, G1
Engel, B1
Einstein, R1
Goodman, AH1
Coats, RA1
Dyson, DH1
Allen, DG1
McDonell, WN1
Ikeo, T1
Wasserman, MA1
Hainsworth, R1
Karim, F1
Stoker, JB1
Beckman, DL1
Bean, JW1
Baslock, DR1
Fincker, JL1
Arnold, P1
Brandt, C1
Rauscher, M1
Vergne, P1
Baïsset, A2
Montastruc, P2
Tran, MA1
Bowman, WC1
Hays, FL1
Webster, AJ1
Corssen, G1
Chodoff, P1
Cotonat, J1
Barrett, AM1
LeDouarec, JC1
Duhault, J1
Laubie, M1
Lydtin, H1
Johnstone, M2
Fowler, NO1
Holmes, JC1
Gaffney, TE1
Privitera, PJ1
Grupp, G1
Ablad, B1
Brändström, A1
Ek, L1
Sjölander, M1
Pettinger, WA1
Augusto, L1
Leon, AS1
Pettit, GW1
Vick, RL1
Yard, AC1
Kadowitz, PJ1
Neetens, A1
Gams, E1
Huntsman, LL1
Chimoskey, JE1
Beard, J1
Lodi, R1
Montanari, C1
Bondioli, A1
Del Torto, T1
Gualtieri, V1
Manenti, A1
Bruni, GC1
Romani, M1
Forni, C1
Papp, JG1
Szekeres, L1
Kaplan, HR1
La Sala, SA1
Liu, CK1
Lee, JY1
Shanks, RG1
Zaidi, SA1
Omiya, Y2
Mjös, OD1
Jenkins, LC1
Lahay, D1
Konga, K1
Mizuguchi, T1
Nakai, K1
Tavernor, WD1
Lees, P1
Toyama, S1
Amemiya, T1
Suzuki, K1
Isa, T1
Morioka, T1
Kuba, Y1
Motoyama, H1
Takenaka, F1
Vergano, F1
Zaccagna, CA1
Oggeri, A1
Marchisio, O1
Tobia, A1
Murakami, S1
Ota, Y1
Saito, S1
Fukuda, A1
Johnson, ES1
Roberts, MH1
Straughan, DW1
Galindo, A1
Brindle, GF1
Gilbert, RG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Propranolol Versus Placebo for Induction of Labor in Nulliparous Patients: a Double-blind Randomized Controlled Trial[NCT03348683]Phase 2240 participants (Actual)Interventional2017-12-11Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of Latent

Time of latent labor defined as <6cm of cervical dilation. (NCT03348683)
Timeframe: average of 24 hours

Interventionhours (Mean)
Propranolol11.0
Placebo11.2

Number of Fetus With Fetal Bradycardia

Count of fetus with fetal bradycardia (<110bpm for >10 minutes within 30 minutes of study drug administration) (NCT03348683)
Timeframe: 30 minutes from drug administration

InterventionParticipants (Count of Participants)
Propranolol1
Placebo0

Number of Fetus With Heart Rate Decelerations

Count of fetus with fetal heart rate decelerations within 30 minutes of study drug administration (NCT03348683)
Timeframe: 30 minutes from drug administration

InterventionParticipants (Count of Participants)
Propranolol15
Placebo13

Number of Neonates With Hypoglycemia

"Neonatal outcome - Number of neonates with hypoglycemia (blood glucose <50).~This population includes only the neonates who had heelsticks to check their blood glucose, which is not a universal practice and was not required by the protocol or IRB. The neonates included were those who met the nursery's risk-based protocol to check blood glucose after birth (ex: infants of diabetic mothers, fetal growth restriction, macrosomia, or symptoms suggestive of hypoglycemia)" (NCT03348683)
Timeframe: Day 1

InterventionParticipants (Count of Participants)
Propranolol11
Placebo8

Number of Neonates With Neonatal Outcome Composite Score = 1

"Composite neonatal outcome score was for any of the following morbidity: Neonatal Intensive Care Unit (NICU) admission, respiratory support (CPAP, nasal cannula, intubation), culture proven sepsis, radiographically proven intracranial hemorrhage, necrotizing enterocolitis, hypoglycemia (for those infants who had sugar checked), and neonatal death.~The composite score was computed as a score of 1 for any indication of neonatal morbidity - neonates who experienced at least one morbidity and the components are given equal weights. Patients who had no evidence of the predefined neonatal morbidities are subsequently given a score of 0. The minimum is 0 and maximum is 1." (NCT03348683)
Timeframe: Day 1

InterventionParticipants (Count of Participants)
Propranolol21
Placebo28

Number of Participants With Maternal Morbidity Composite Score = 1

"Composite maternal morbidity score consists of a count of postpartum hemorrhage, transfusion, hysterectomy, placental abruption, chorioamnionitis, shoulder dystocia, episiotomy, higher order laceration, and ICU admission.~The composite score was computed as a score of 1 for any indication of maternal morbidity, that is the participant experienced at least one maternal morbidity, and the components are given equal weights. Participants who had no evidence of the predefined maternal morbidities are subsequently given a score of 0. The minimum is 0 and maximum is 1." (NCT03348683)
Timeframe: average of 24 hours

InterventionParticipants (Count of Participants)
Propranolol35
Placebo49

Number of Participants With Postpartum Hemorrhage

Greater than 500cc of blood expelled during a vaginal delivery or greater than 1000cc of blood expelled during a cesarean section (NCT03348683)
Timeframe: 30 minutes from drug administration

InterventionParticipants (Count of Participants)
Propranolol15
Placebo26

Time From Beginning of Induction to Delivery

The time of induction (based on time of foley balloon placement for cervical ripening or misoprostol administration) to the time of delivery of the infant. (NCT03348683)
Timeframe: average of 24 hours

Interventionhours (Mean)
Propranolol13.8
Placebo14.3

Number of Participants With Various Mode of Delivery

Number of various mode of delivery - count of Vaginal delivery, vacuum assisted vaginal delivery, forceps assisted vaginal delivery, cesarean section (NCT03348683)
Timeframe: average of 24 hours

,
InterventionParticipants (Count of Participants)
Spontaneous vaginal deliveryVacuum assisted vaginal deliveryForceps assisted vaginal deliveryCesarean section
Placebo6110840
Propranolol643846

Reviews

7 reviews available for isoproterenol and Anesthesia

ArticleYear
Recent developments in the physiology of bronchomotor tone and the pharmacology of bronchodilators.
    International anesthesiology clinics, 1977,Summer, Volume: 15, Issue:2

    Topics: Aminophylline; Anesthesia; Atropine; Bronchi; Bronchodilator Agents; Histamine; Humans; Isoprotereno

1977
[Evaluation of application of cornary vasodilator agents during anesthesia].
    Masui. The Japanese journal of anesthesiology, 1975, Volume: 24, Issue:2

    Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dipyridamole

1975
Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2: Cardiovascular system.
    Experientia, 1986, Mar-15, Volume: 42, Issue:3

    Topics: Anesthesia; Angiotensin II; Animals; Blood Pressure; Calcium; Cardiac Output; Cardiovascular Physiol

1986
[Beta-receptor-blocking agents and anesthesia].
    Die Medizinische Welt, 1969, Aug-30, Volume: 35

    Topics: Adrenal Gland Neoplasms; Anesthesia; Angina Pectoris; Arrhythmias, Cardiac; Asthma; Cardiomyopathy,

1969
Reflections on beta-adrenergic blockade in anaesthetics.
    British journal of anaesthesia, 1970, Volume: 42, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Ethanolamines; Halothane; Heart Rate; Humans; Hyperthyroidi

1970
Myocardial function and anesthesia.
    International anesthesiology clinics, 1972,Winter, Volume: 10, Issue:4

    Topics: Anesthesia; Aorta; Blood Pressure; Calcium; Cardiac Output; Coronary Circulation; Depression, Chemic

1972
Venous pressure and other thoughts.
    Proceedings of the Royal Society of Medicine, 1969, Jul-07, Volume: 62, Issue:7

    Topics: Anesthesia; Blood Pressure; Blood Volume Determination; Cardiac Output; Catecholamines; Chlorpromazi

1969

Trials

2 trials available for isoproterenol and Anesthesia

ArticleYear
Simulation of an epidural test dose with intravenous epinephrine in sevoflurane-anesthetized children.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:5

    Topics: Anesthesia; Anesthetics, Inhalation; Atropine; Blood Pressure; Child; Child, Preschool; Epinephrine;

1998
Evaluating hemodynamic and T wave criteria of simulated intravascular test doses using bupivacaine or isoproterenol in anesthetized children.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:3

    Topics: Adrenergic beta-Agonists; Anesthesia; Anesthetics, Local; Blood Pressure; Bupivacaine; Child, Presch

2000

Other Studies

180 other studies available for isoproterenol and Anesthesia

ArticleYear
Discovery of a novel series of biphenyl benzoic acid derivatives as potent and selective human beta3-adrenergic receptor agonists with good oral bioavailability. Part I.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Administration, Oral; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Anesthesia; Ani

2008
Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice.
    Journal of visualized experiments : JoVE, 2019, 10-03, Issue:152

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Disease Models, Animal; Echocardiography; Heart Failu

2019
Beta-adrenergic activation induces cardiac collapse by aggravating cardiomyocyte contractile dysfunction in bupivacaine intoxication.
    PloS one, 2018, Volume: 13, Issue:10

    Topics: Anesthesia; Animals; Blood Pressure; Bupivacaine; Cardiotoxicity; Chloral Hydrate; Disease Models, A

2018
Coronary blood flow in the anesthetized American alligator (Alligator mississippiensis).
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2016, Volume: 191

    Topics: Acetylcholine; Adenosine; Alligators and Crocodiles; Anesthesia; Animals; Coronary Circulation; Coro

2016
Modulation of {beta}-adrenoceptor signaling in the hearts of 4-wk simulated weightlessness rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Anesthesia; Animals; Body Weight; Colforsin; Cyclic AMP

2008
[Warning for error risk between isoprenaline and suxamethonium injectable vials].
    Annales francaises d'anesthesie et de reanimation, 2008, Volume: 27, Issue:9

    Topics: Anesthesia; Drug Labeling; Humans; Isoproterenol; Medication Errors; Risk Factors; Succinylcholine

2008
Noradrenaline triggers muscle tone by amplifying glutamate-driven excitation of somatic motoneurones in anaesthetized rats.
    The Journal of physiology, 2008, Dec-01, Volume: 586, Issue:23

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Recep

2008
p38 MAP kinase inhibitor reverses stress-induced myocardial dysfunction in vivo.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:4

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Cardiomyopathies; Dose-Response Relationship, Drug; E

2009
Effect of adrenaline, noradrenaline and isoprenaline on hepatic bile secretion of anaesthetized dogs.
    Nature, 1966, Dec-31, Volume: 212, Issue:5070

    Topics: Anesthesia; Animals; Bile; Dogs; Dose-Response Relationship, Drug; Epinephrine; Female; Isoprotereno

1966
Pharmacologic characteristics of bladder micturition function in anesthetized mice.
    Comparative medicine, 2010, Volume: 60, Issue:6

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Agoni

2010
Beta-adrenergic stimulation restores oxygen extraction reserve during acute normovolemic hemodilution.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:4

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Carbon Monoxide; Dogs; Female; Heart Rate; Hemodiluti

2002
Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling.
    Circulation research, 2003, Mar-07, Volume: 92, Issue:4

    Topics: Action Potentials; Anesthesia; Animals; Blood Pressure; Calcium; Cardiomyopathy, Hypertrophic, Famil

2003
Thoracic massage permits use of echocardiography in unanesthetized rats.
    Comparative medicine, 2003, Volume: 53, Issue:3

    Topics: Anesthesia; Animals; Cardiotonic Agents; Consciousness; Echocardiography; Heart Massage; Heart Ventr

2003
Evaluation of sympathetic reflex effects on the inotropic action of nitroglycerin, quinidine, papaverine, aminophylline and isoproterenol.
    The Journal of pharmacology and experimental therapeutics, 1958, Volume: 122, Issue:3

    Topics: Aminophylline; Anesthesia; Anesthesia, Conduction; Humans; Isoproterenol; Nitroglycerin; Papaverine;

1958
Prevention of post-operative chest complications; a new technique using isoprenaline aerosols during anaesthesia.
    Anaesthesia, 1959, Volume: 14, Issue:1

    Topics: Aerosols; Anesthesia; Anesthesia, Inhalation; Anesthesiology; Isoproterenol; Postoperative Complicat

1959
[The effect of adrenalin, noradrenalin and isoproterenol on gas metabolism and body temperature of narcotized rats by permanent intravenous infusion].
    Acta biologica et medica Germanica, 1962, Volume: 8

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Animals; Barbiturates; Body Temperature; Epinephrin

1962
[Noradrenalin loss from the isolated rabbit heart following sympathetic nerve irritation and its pharmacological alteration].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1962, Volume: 244

    Topics: Anesthesia; Anesthesia, Local; Animals; Autonomic Nervous System; Calcium; Cocaine; Ganglia; Ganglia

1962
ANESTHESIA FOR PATIENTS WITH ASTHMA.
    The American surgeon, 1964, Volume: 30

    Topics: Adrenal Cortex Hormones; Anesthesia; Anesthesia, Intravenous; Anesthesia, Spinal; Anesthesiology; As

1964
[ALLERGY AND ANESTHESIA].
    Nordisk medicin, 1964, Nov-26, Volume: 72

    Topics: Adrenal Cortex Hormones; Allergens; Anaphylaxis; Anesthesia; Anesthetics; Drug Hypersensitivity; Dru

1964
[ON THE PREVENTION OF ASTHMOID COMPLICATIONS OF GENERAL ANESTHESIA].
    Munchener medizinische Wochenschrift (1950), 1964, Jul-17, Volume: 106

    Topics: Aerosols; Anesthesia; Anesthesia, General; Anesthesiology; Asthma; Bronchitis; Bronchodilator Agents

1964
VENTRICULAR ARRHYTHMIAS DURING HALOTHANE ANAESTHESIA: EFFECT OF ISOPROTERENOL, AMINOPHYLLINE, AND EPHEDRINE.
    Canadian Anaesthetists' Society journal, 1965, Volume: 12

    Topics: Aminophylline; Anesthesia; Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Brugada Syndrome;

1965
[LIFE-SAVING TREATMENT IN VERY SEVERE ACUTE ASTHMATIC ATTACKS (STATUS ASTHMATICUS)].
    Munchener medizinische Wochenschrift (1950), 1965, May-14, Volume: 107

    Topics: Anesthesia; Asthma; Bronchial Spasm; Drug Therapy; Humans; Intubation; Intubation, Intratracheal; Is

1965
The effect of dehydroepiandrosterone on regional blood flow in prepubertal anaesthetized pigs.
    The Journal of physiology, 2004, May-15, Volume: 557, Issue:Pt 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Anes

2004
Prolactin induces regional vasoconstriction through the beta2-adrenergic and nitric oxide mechanisms.
    Endocrinology, 2007, Volume: 148, Issue:8

    Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anest

2007
Anaphylactic shock in a beta-blocked child: usefulness of isoproterenol.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:9

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anaphylaxis; Anesthesia; Aortic Stenosis, Sub

2007
A comparison of the adrenergic receptor blocking properties of 1-(4'-methylphenyl)-2-isopropylamino-propanol-HCl and propranolol.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 156, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Dogs; Drug Antagonism; Female; Gastrointestinal Motility; Heart

1967
Central mechanisms of the isoprenaline-induced hypotension in anesthetized and conscious rats.
    General pharmacology, 1984, Volume: 15, Issue:6

    Topics: Anesthesia; Animals; Consciousness; Hypotension; Injections, Intraventricular; Isoproterenol; Male;

1984
Pharmacological evidence for differences in the beta-adrenoreceptor populations mediating atrial and ventricular chronotropic responses in the unanaesthetized dog.
    Journal of autonomic pharmacology, 1984, Volume: 4, Issue:4

    Topics: Alprenolol; Anesthesia; Animals; Dogs; Electrocardiography; Female; Heart Rate; Isoproterenol; Male;

1984
beta-Adrenoceptor mediated actions of R0363 and (-)-isoprenaline in anaesthetized cats, rats, and rabbits.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:5

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Blood Pressure; Catechols; Cats; Heart Rate; Isoprote

1980
The effect of beta-adrenoceptor blocking agents, with differing ancillary properties, on the arrhythmias resulting from acute coronary artery ligation in anaesthetized rats.
    British journal of pharmacology, 1983, Volume: 79, Issue:4

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cell

1983
Assessment of adrenergic beta-blockade in the anesthetized rat at different baseline values.
    General pharmacology, 1984, Volume: 15, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Dose-Response Relationship, Drug;

1984
Cetamolol: cardiovascular effects of a new cardioselective beta-adrenoceptor blocker possessing partial agonistic activity and lacking membrane-stabilizing activity.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:6

    Topics: Acetamides; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Ca

1984
Aspects of the cardiovascular pharmacology of exaprolol.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:9

    Topics: Action Potentials; Adrenergic beta-Antagonists; Anesthesia; Animals; Arrhythmias, Cardiac; Cats; Cor

1984
Hemodynamic effects of arotinolol in anesthetized dogs and its affinities for adrenoceptors in vitro.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 267, Issue:1

    Topics: Adrenergic beta-Antagonists; Anesthesia; Angiotensin II; Animals; Blood Pressure; Dogs; Drug Interac

1984
Effects of isoprenaline, levodopa and a phosphodiesterase inhibitor (ICI 63,197) on cyclic AMP levels and contractions of soleus muscles in anesthetized cats.
    Clinical and experimental pharmacology & physiology, 1981, Volume: 8, Issue:1

    Topics: Anesthesia; Animals; Cats; Cyclic AMP; Female; Isoproterenol; Levodopa; Male; Muscle Contraction; Mu

1981
Converting enzyme inhibition and modulation of plasma renin activity with captopril in anesthetized rats.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 253, Issue:1

    Topics: Acetylcholine; Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors;

1981
Effects of ritodrine hydrochloride, a beta 2-adrenoceptor stimulant, on uterine motilities in late pregnancy.
    Japanese journal of pharmacology, 1984, Volume: 35, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Female; Heart Rate; Isoproterenol; Isoxsuprine; Oxytocin; Pregn

1984
A canine model of transient myocardial dysfunction regional shortening in the presence of critical stenosis and cardiac stimulation.
    Journal of pharmacological methods, 1984, Volume: 12, Issue:4

    Topics: Anesthesia; Angina Pectoris; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Diseas

1984
Effects of prenalterol and its N-homoveratryl derivative in the anaesthetized cat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 323, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Cardiac Output; Cats; Female; Heart Rate; Hemodynamics; Isoprot

1983
Hepatic venoconstrictor effects of isoproterenol and nifedipine in anesthetized cats.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:6

    Topics: Adrenalectomy; Anesthesia; Animals; Blood Pressure; Cats; Denervation; Hepatic Veins; Isoproterenol;

1984
[Experimental studies on therapeutic modification of sparteine poisoning].
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:10

    Topics: Anesthesia; Animals; Antidotes; Cardiac Output; Dopamine; Electrocardiography; Heart Rate; Isoproter

1982
Vasopressor and depressor actions of angiotensin in the anesthetized fowl.
    The American journal of physiology, 1982, Volume: 242, Issue:3

    Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Chickens; Epinephr

1982
A simple technique for determining contractility, intraventricular pressure, and heart rate in the anesthetized guinea pig.
    Journal of pharmacological methods, 1982, Volume: 8, Issue:3

    Topics: Anesthesia; Animals; Guinea Pigs; Heart; Heart Rate; Imidazoles; Isoproterenol; Male; Myocardial Con

1982
Studies on the mechanism of the positive-inotropic action of AR-L 115 BS, a new cardiotonic drug.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:1a

    Topics: Anesthesia; Animals; Cardiotonic Agents; Cats; Female; Guinea Pigs; Imidazoles; In Vitro Techniques;

1981
The effect of subendocardial systolic pressure on the ascending aortic blood flow and the left coronary blood flow during an overdose of isoproterenol in anesthetized dogs.
    The Tokushima journal of experimental medicine, 1981, Volume: 28, Issue:3-4

    Topics: Anesthesia; Animals; Aorta; Blood Pressure; Coronary Circulation; Dogs; Endocardium; Isoproterenol;

1981
Effects on blood pressure of noradrenaline and isoprenaline administered into the third ventricle of the brain of anaesthetized and conscious cats.
    Journal of autonomic pharmacology, 1980, Volume: 1, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Cats; Cisterna Magna; Female; Hemodynamics; Injections, Intrave

1980
Application of combined Fick and radioactive microsphere methods for determination of systemic and regional hemodynamics in conscious rat.
    Japanese circulation journal, 1980, Volume: 44, Issue:5

    Topics: Anesthesia; Animals; Cardiac Output; Consciousness; Hemodynamics; Isoproterenol; Methods; Microspher

1980
Effect of interventions that increase cyclic AMP levels on susceptibility to ventricular fibrillation in unanesthetized dogs.
    European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Anesthesia;

1994
Hemodynamic and coronary vasodilative properties of a selective and full beta 1-adrenoceptor agonist, T-0509, in comparison with isoproterenol in anesthesized dogs.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:2

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-Agonists; Anesthesia; Animals; Coronary Circula

1994
Hyperresponsiveness of the airways following exposure of guinea-pigs to racemic mixtures and distomers of beta 2-selective sympathomimetics.
    Pulmonary pharmacology, 1994, Volume: 7, Issue:6

    Topics: Administration, Topical; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Airway Resis

1994
SR 33589, a new amiodarone-like antiarrhythmic agent: anti-adrenoceptor activity in anaesthetized and conscious dogs.
    European journal of pharmacology, 1995, Jun-06, Volume: 279, Issue:1

    Topics: Administration, Oral; Adrenergic Antagonists; Amiodarone; Anesthesia; Animals; Anti-Arrhythmia Agent

1995
Cerebral reactive hyperaemia and arterial pressure in anaesthetized goats.
    Acta physiologica Scandinavica, 1995, Volume: 153, Issue:4

    Topics: Anesthesia; Animals; Aorta, Thoracic; Arteries; Blood Pressure; Cerebrovascular Circulation; Female;

1995
[Effect of arotinolol on the incomplete tetanic contractions of the cat soleus muscle--relation to its anti-tremorgenic action].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1993, Volume: 102, Issue:2

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Cats; Dose-Response Relationship, Drug; Epinephrin

1993
Regulation of norepinephrine release by beta 2-adrenergic receptors during halothane anesthesia.
    Anesthesiology, 1995, Volume: 82, Issue:6

    Topics: Anesthesia; Animals; Dogs; Female; Halothane; Isoproterenol; Norepinephrine; Receptors, Adrenergic,

1995
Heterogenous activity of BRL 35135, a beta 3-adrenoceptor agonist, in thermogenesis and increased blood flow in brown adipose tissue in anaesthetized rats.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:7

    Topics: Adipose Tissue, Brown; Adrenergic beta-Agonists; Anesthesia; Animals; Blood Pressure; Body Temperatu

1994
Effect of flosequinan on ischaemia-induced arrhythmias and on ventricular cyclic nucleotide content in the anaesthetized rat.
    British journal of pharmacology, 1993, Volume: 108, Issue:4

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressu

1993
Selective beta 1-adrenoceptor agonist activity of denopamine and its derivatives in dogs.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:5

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Catecholamines; Dogs; Et

1993
Cardiotonic activity of the water soluble forskolin derivative 8,13-epoxy-6 beta-(piperidinoacetoxy)- 1 alpha, 7 beta, 9 alpha-trihydroxy-labd- 14en-11-one.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:3

    Topics: Adenosine Diphosphate; Anesthesia; Animals; Cardiotonic Agents; Cats; Colforsin; Cricetinae; Dogs; E

1993
Inhibitory effect of inhaled wood smoke on the discharge of pulmonary stretch receptors in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:4

    Topics: Acetazolamide; Anesthesia; Animals; Bronchodilator Agents; Carbon Dioxide; Carbonic Anhydrase Inhibi

1998
Effects of nitric oxide synthase inhibition on sympathetically-mediated tachycardia.
    European journal of pharmacology, 1999, Jan-22, Volume: 365, Issue:2-3

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Atropine; Blood Pressure; Cyclic AMP; Drug Interactions;

1999
Effects of Saiko-ka-ryukotsu-borei-to, a Japanese Kampo medicine, on tachycardia and central nervous system stimulation induced by theophylline in rats and mice.
    Japanese journal of pharmacology, 1999, Volume: 79, Issue:3

    Topics: Anesthesia; Animals; Atrial Function, Right; Blood Pressure; Cardiotonic Agents; Central Nervous Sys

1999
Effective dose of isoproterenol-containing test dose in anesthetized children.
    Anesthesia and analgesia, 1999, Volume: 88, Issue:5

    Topics: Adrenergic beta-Agonists; Anesthesia; Child; Heart Rate; Humans; Isoproterenol

1999
Eugenodilol: a third-generation beta-adrenoceptor blocker, derived from eugenol, with alpha-adrenoceptor blocking and beta2-adrenoceptor agonist-associated vasorelaxant activities.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Aorta, Thoracic; Bradyca

1999
Electrophysiologic, cardiohemodynamic and beta-blocking actions of a new ultra-short-acting beta-blocker, ONO-1101, assessed by the in vivo canine model in comparison with esmolol.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Anti-Arrhythmia Agents;

1999
Alteration in the D-amino acid content of the rat pineal gland under anesthesia.
    Amino acids, 1999, Volume: 17, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Aspartic Acid; Isoproterenol; Leucine; Male; Pinea

1999
Effects of beta-adrenergic stimulation on the acutely obstructed ureter in dogs.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:1

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Blood Pressure; Butylscopolammonium Bromide; Catheter

2000
Characterization of beta-adrenoceptor subtypes in the ferret urinary bladder in vitro and in vivo.
    European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Dioxoles

2000
Effects of isoproterenol and butylscopolamine on the friction between an artificial stone and the intraureteral wall in anesthetized rabbits.
    The Journal of urology, 2001, Volume: 166, Issue:3

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Butylscopolammonium Bromide; Friction; Isoproterenol;

2001
Effect of estrogen replacement therapy on distribution of myocardial blood flow in female anesthetized rabbits.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:3

    Topics: Acetylcholine; Anesthesia; Animals; Blood Flow Velocity; Blood Pressure; Cardiotonic Agents; Chromon

2001
Lipopolysaccharide-induced leptin release is neurally controlled.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Dec-04, Volume: 98, Issue:25

    Topics: Adipocytes; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Ane

2001
Characterization of beta-adrenoceptor subtype in bladder smooth muscle in cynomolgus monkey.
    Japanese journal of pharmacology, 2002, Volume: 88, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Female; Isoproterenol; M

2002
Noradrenaline, infused locally, reduces arrhythmia severity during coronary artery occlusion in anaesthetised dogs.
    Cardiovascular research, 2002, Volume: 55, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Anesthesia; Animals; Arrh

2002
Actions of procaterol (OPC-2009), a new beta2-adrenoceptor stimulant, on pulmonary resistance, contractions of the soleus muscle, and cardiovascular system of the anaesthetized cat.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:5

    Topics: Adrenergic beta-Agonists; Airway Resistance; Albuterol; Amino Alcohols; Anesthesia; Animals; Cats; F

1978
Beta-adrenoceptor blockade by atenolol, metoprolol and propranolol in the anaesthetized cat.
    European journal of pharmacology, 1979, May-01, Volume: 55, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Cats; Female; Heart Rate; Hemodynamics;

1979
[Bronchodilating action of (--)-1-(3, 4, 5-trimethoxybenzyl)-7-hydroxy-1, 2, 3, 4-tetrahydroisoquinoloine HCl (l-MTI) (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1978, Volume: 74, Issue:7

    Topics: Adrenalectomy; Anesthesia; Animals; Bronchodilator Agents; Cats; Dogs; Dose-Response Relationship, D

1978
Lowering of innate resistance of the lungs to the growth of blood-borne cancer cells in states of topical and systemic stress.
    British journal of cancer, 1976, Volume: 33, Issue:1

    Topics: Adrenalectomy; Aminophylline; Anesthesia; Animals; Carcinoma 256, Walker; Cell Survival; Clone Cells

1976
Effects of morphine on coronary and left ventricular dynamics in conscious dogs.
    The Journal of clinical investigation, 1975, Volume: 55, Issue:2

    Topics: Adrenalectomy; Anesthesia; Animals; Blood Pressure; Carbon Dioxide; Consciousness; Coronary Circulat

1975
Effect of bulbocapnine as a peripheral dopamine receptor antagonists in the anesthetized cat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 289, Issue:2

    Topics: Anesthesia; Animals; Aporphines; Blood Pressure; Cats; Dopamine; Female; Isoproterenol; Male; Phenox

1975
Age-associated decrease in heart rate response to isoproterenol in dogs.
    Mechanisms of ageing and development, 1979, Volume: 10, Issue:1-2

    Topics: Aging; Anesthesia; Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Is

1979
Studies of the hemopoietic microenvironment. VII. Neural mechanisms in splenic microvascular regulation in mice.
    Microvascular research, 1977, Volume: 14, Issue:3

    Topics: Adenosine; Anesthesia; Animals; Arterioles; Blood Flow Velocity; Bradykinin; Catecholamines; Female;

1977
Mechanism for the increase in plasma renin activity by pentobarbital anesthesia.
    Life sciences, 1978, May-01, Volume: 22, Issue:17

    Topics: Anesthesia; Animals; Blood Pressure; Dogs; Female; Heart Rate; Indomethacin; Isoproterenol; Pentobar

1978
Effect of centrally administered noradrenaline and isoprenaline on splanchnic nerve activity in anaesthetised and conscious cats [proceedings].
    British journal of pharmacology, 1978, Volume: 64, Issue:3

    Topics: Anesthesia; Animals; Cats; Isoproterenol; Norepinephrine; Splanchnic Nerves

1978
Comparison between theoretical and directly measured pulse propagation velocities in the aorta of the anesthetised dog.
    Cardiovascular research, 1978, Volume: 12, Issue:7

    Topics: Anesthesia; Animals; Aorta, Abdominal; Dogs; Elasticity; Isoproterenol; Norepinephrine; Pulse

1978
Fatty acid incorporation into human adipose tissue (FIAT) in hypertriglyceridaemia.
    Acta medica Scandinavica. Supplementum, 1976, Volume: 591

    Topics: Adipose Tissue; Adult; Aged; Anesthesia; Biopsy, Needle; Fatty Acids; Female; Glucose; Glucose Toler

1976
Bronchodilating actions of (+/-)-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline (TMI) derivatives in anesthetized cats.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:4

    Topics: Anesthesia; Animals; Blood Pressure; Bronchodilator Agents; Cats; Dose-Response Relationship, Drug;

1977
[Intensive acre and resuscitation in bronchial asthma and the asthmatic state].
    Terapevticheskii arkhiv, 1975, Volume: 47, Issue:8

    Topics: Acidosis; Adolescent; Adult; Aminophylline; Anesthesia; Asthma; Critical Care; Droperidol; Ephedrine

1975
Allergic bronchoconstriction and its drug-induced reversal in anesthetized, ovalbumin-sensitized cats.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 13, Issue:4

    Topics: Airway Resistance; Aminophylline; Anesthesia; Animals; Bronchi; Cats; Female; Hypersensitivity; Isop

1976
Experimental cardiovascular depressant effects of garlic (Allium sativum) dialysate.
    Journal of ethnopharmacology, 1992, Volume: 37, Issue:2

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Blood Pressure; Dialysis; Dogs; Electrocardiography; Fe

1992
Cardiovascular and renal effects of milrinone in beta-adrenoreceptor blocked and non-blocked anaesthetized dogs.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Gas Analysis; Dogs; Dopamine; Electrolytes;

1991
Effects of the partial beta 1-adrenergic agonist, xamoterol, on hemodynamics and regional myocardial function during acute coronary occlusion in dogs.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:2

    Topics: Acute Disease; Adrenergic beta-Antagonists; Anesthesia; Animals; Coronary Disease; Dogs; Heart; Hemo

1990
Effects of beta 1- and beta 2-adrenoceptor stimulation on hemodynamics in the anesthetized rat.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:5

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Blood Pressure

1990
Comparative effects of arotinolol, labetalol and propranolol on regional myocardial dysfunction induced by flow-limiting coronary stenosis in anesthetized dogs.
    Japanese journal of pharmacology, 1990, Volume: 53, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Cardiomyopathies; Coronary Vessels

1990
Comprehensive evaluation of cardiovascular function in the anesthetized rat.
    Methods and findings in experimental and clinical pharmacology, 1991, Volume: 13, Issue:9

    Topics: Adenosine Triphosphatases; Anesthesia; Animals; Blood Pressure; Calcium; Cardiac Output; Heart Funct

1991
Acute complete heart block during anesthesia in a patient with severe coronary artery disease: effect of scopolamine versus ischemia of the AV node.
    Anesthesiology, 1991, Volume: 75, Issue:2

    Topics: Aged; Anesthesia; Atrioventricular Node; Atropine; Cardiopulmonary Bypass; Coronary Disease; Electro

1991
Cardiovascular and autonomic pharmacology of the macrolide antibiotic LY281389 in anesthetized beagles and in isolated smooth and cardiac muscles.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:7

    Topics: Acetylcholine; Anesthesia; Angiotensin I; Animals; Anti-Bacterial Agents; Autonomic Nervous System;

1991
Autonomic and haemodynamic responses to SK & F 101468 (ropinirole), a DA2 agonist, in anaesthetised cats.
    European journal of pharmacology, 1990, Jan-17, Volume: 175, Issue:3

    Topics: Acetylcholine; Anesthesia; Animals; Autonomic Nervous System; Blood Pressure; Cats; Coronary Circula

1990
Effects of dilevalol in the anesthetized pig with a partially occluded coronary artery.
    Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Chloralose; Coronary

1990
The involvement of desipramine-sensitive processes in the extraction of various catecholamines from plasma in the anaesthetized rabbit.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: Anesthesia; Animals; Catecholamines; Desipramine; Dopamine; Epinephrine; Female; Isoproterenol; Male

1990
The actions of human atrial natriuretic factor on hepatic arterial and portal vascular beds of the anaesthetized dog.
    British journal of pharmacology, 1990, Volume: 99, Issue:4

    Topics: Anesthesia; Animals; Atrial Natriuretic Factor; Blood Pressure; Dogs; Hepatic Artery; Injections, In

1990
Cardiovascular effects of bromocriptine in rats: role of peripheral adrenergic and dopaminergic receptors.
    Journal of autonomic pharmacology, 1990, Volume: 10, Issue:2

    Topics: Anesthesia; Animals; Blood Pressure; Bromocriptine; Carbachol; Decerebrate State; Electric Stimulati

1990
Functional evidence for heterogeneity of ocular alpha 2-adrenoceptors.
    Proceedings of the Western Pharmacology Society, 1990, Volume: 33

    Topics: Anesthesia; Animals; Brimonidine Tartrate; Cats; Ciliary Body; Cyclic AMP; Dose-Response Relationshi

1990
Mediation of 5-hydroxytryptamine-induced tachycardia in the pig by the putative 5-HT4 receptor.
    British journal of pharmacology, 1990, Volume: 100, Issue:4

    Topics: Anesthesia; Animals; Benzamides; Blood Pressure; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo C

1990
Vasoactive intestinal polypeptide facilitates atrioventricular nodal conduction and shortens atrial and ventricular refractory periods in conscious and anesthetized dogs.
    Circulation research, 1990, Volume: 67, Issue:6

    Topics: Anesthesia; Animals; Atrial Function; Atrioventricular Node; Autonomic Nervous System; Blood Pressur

1990
The cardiac contractile function and hemodynamic control in rats after chronic adriamycin treatment.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:2

    Topics: Anesthesia; Animals; Blood Pressure; Cardiac Output; Doxorubicin; Heart Rate; Hemodynamics; Infusion

1990
Anesthesia and pressor responsiveness in chronic bile-duct-ligated dogs.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:4

    Topics: Anesthesia; Angiotensin II; Animals; Bile Ducts; Blood Pressure; Cholestasis; Dogs; Fentanyl; Haloth

1990
Mechanism of the hypotensive effect of a new beta-adrenergic blocking drug, arotinolol (S-596) in anesthetized rabbits.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:2

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine

1985
Effects of alterations in sympathetic nervous activity on the severity of reperfusion-induced arrhythmias in anaesthetised rats.
    Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Arrhythmias, Cardiac

1987
Pharmacological and hemodynamic profile of nebivolol, a chemically novel, potent, and selective beta 1-adrenergic antagonist.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anesthesia; Animals; Atenolol; Ben

1988
Comparison of the effects of cetamolol and atenolol on epinephrine- and isoproterenol-induced hypokalemia in anesthetized dogs.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:1

    Topics: Acetamides; Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Dogs; Dose-Response Relation

1989
Beta-adrenoceptor blocking activity of diprafenone in anesthetized dogs: comparison with propafenone and propranolol.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Anti-Arrhythmia Agents; Dihydroalprenolol; Dogs; F

1989
Further evidence of interaction between vasodilator beta 2- and vasoconstrictor alpha 2-adrenoceptor-mediated responses in maintaining vascular tone in anesthetized rats.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:6

    Topics: Anesthesia; Animals; Blood Pressure; Catecholamines; Clenbuterol; Heart Rate; Isoproterenol; Male; M

1989
Ventricular fibrillation is reduced in hypothyroid rats with enhanced myocardial alpha-adrenoceptor responsiveness.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Anesthesia; Animals; Coronary Disease; Hypothyroidism; Isoproterenol; Male; Myocardial Reperfusion I

1989
The cardiovascular pharmacology of xamoterol, cicloprolol, prenalterol and pindolol in the anaesthetised dog.
    British journal of clinical pharmacology, 1989, Volume: 28 Suppl 1

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Hemodynamics;

1989
The interaction of the enantiomers of carvedilol with alpha 1- and beta 1-adrenoceptors.
    Chirality, 1989, Volume: 1, Issue:4

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Carbazoles; Carvedilol; Decerebrate State; Guinea

1989
The cardiovascular pharmacology of ICI 170777 ((6RS)-6-methyl-5-(pyrid-4-yl)-3H,6H-1,3,4- thiadiazin-2-one) a novel compound with positive inotropic and vasodilator effects.
    British journal of pharmacology, 1989, Volume: 97, Issue:2

    Topics: Anesthesia; Animals; Cats; Dogs; Female; Heart Rate; Hemodynamics; Hindlimb; In Vitro Techniques; Is

1989
The relaxant properties of human calcitonin gene-related peptide on vascular and extravascular capsular) smooth muscle of the isolated blood-perfused spleen of the anaesthetized dog.
    British journal of pharmacology, 1989, Volume: 96, Issue:4

    Topics: Anesthesia; Animals; Calcitonin Gene-Related Peptide; Dogs; Humans; In Vitro Techniques; Isoproteren

1989
Local modulation of adrenal catecholamines release by beta-2 adrenoceptors in the anaesthetized dog.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:1

    Topics: Adrenal Medulla; Anesthesia; Animals; Dogs; Drug Synergism; Electric Stimulation; Epinephrine; Femal

1988
Beta-adrenergic receptor mediated release of tissue plasminogen activator in anaesthetized dogs.
    Thrombosis research, 1988, Apr-01, Volume: 50, Issue:1

    Topics: Anesthesia; Animals; Dogs; Fibrinolysis; Isoproterenol; Propranolol; Receptors, Adrenergic, beta; Ti

1988
Assessment of beta-adrenoceptor blockade during anesthesia in humans: use of isoproterenol dose-response curves.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Anesthesia; Blood Pressure; Dose-Response Relationship, Drug; Hea

1985
Antidiuretic effects of alpha- and beta-adrenoceptor agonists microinjected into the hypothalamic supraoptic nucleus in a water-loaded and ethanol-anesthetized rat.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Anesthesia; Animals; Blood Pressure; Diuresis;

1985
The cardiac effects of amitraz in the guinea-pig in vivo and in vitro.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1986, Volume: 83, Issue:2

    Topics: Acetylcholine; Anesthesia; Animals; Atropine; Guinea Pigs; Heart; Hemodynamics; Histamine; In Vitro

1986
Pharmacological studies on the intrinsic sympathomimetic activity of the beta-adrenoceptor antagonist mepindolol.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:5

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Heart; Hemodynamics; In Vitro Techniques; Isoprote

1986
Development of a method to determine autonomic nervous system function in the rat.
    Metabolism: clinical and experimental, 1987, Volume: 36, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Autonomic Nervous System; Circadian Rhythm; Diabe

1987
Influence of isoproterenol on plasma immunoreactive atrial natriuretic peptide and plasma vasopressin in the anesthetized rabbit.
    Pflugers Archiv : European journal of physiology, 1987, Volume: 408, Issue:2

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; B

1987
Electrical control activity of the lower esophageal sphincter in unanesthetized opossums.
    The American journal of physiology, 1987, Volume: 252, Issue:4 Pt 1

    Topics: Anesthesia; Animals; Atropine; Duodenum; Eating; Electrophysiology; Esophagogastric Junction; Esopha

1987
Cardiac and renovascular effects in the anaesthetized dog of BW A575C: a novel angiotensin converting enzyme inhibitor with beta-adrenoceptor blocking properties.
    British journal of pharmacology, 1988, Volume: 93, Issue:1

    Topics: Adrenergic beta-Antagonists; Anesthesia; Angiotensin-Converting Enzyme Inhibitors; Animals; Dogs; En

1988
Different responses to beta-adrenoceptor blocking drugs of the blood pressure and heart rate in the urethane-anesthetized dog and rat.
    Japanese journal of pharmacology, 1988, Volume: 47, Issue:1

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Catecholamines; Decerebrate State;

1988
Bisoprolol improves perfusion of ischaemic myocardium in anaesthetized pigs.
    British journal of pharmacology, 1988, Volume: 95, Issue:2

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Bisoprolol; Coronary Circulation; Coronary Disease; Hemod

1988
The sympathomimetic activity of (+/-)-pindolol at beta 1- and beta 2-adrenoceptor sites.
    European journal of pharmacology, 1985, Feb-12, Volume: 109, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Cats; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Iso

1985
Similarities and differences in the effects of verapamil, diltiazem and nifedipine on arterial baroreflexes of anesthetized cats.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 275, Issue:1

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Carotid Arteries; Cats; Diltiazem; Electric Stimu

1985
Role of alpha-adrenergic receptors in the intrinsic inotropic selectivity of dobutamine in anesthetized dogs.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:6

    Topics: Anesthesia; Animals; Dobutamine; Dogs; Female; Hemodynamics; Hexamethonium Compounds; Isoproterenol;

1985
Role of beta adrenergic receptors in carotid body function of the goat.
    Respiration physiology, 1986, Volume: 64, Issue:2

    Topics: Anesthesia; Animals; Carotid Body; Chemoreceptor Cells; Denervation; Goats; Hypoxia; Isoproterenol;

1986
Antagonistic effects of bisoprolol on several beta-adrenoceptor-mediated actions in anaesthetized cats.
    European journal of pharmacology, 1986, Apr-16, Volume: 123, Issue:2

    Topics: Anesthesia; Animals; Atenolol; Bisoprolol; Blood Pressure; Bronchi; Cardiovascular Physiological Phe

1986
Neuronal source of plasma dihydroxyphenylalanine.
    The Journal of clinical endocrinology and metabolism, 1987, Volume: 64, Issue:4

    Topics: Adolescent; Adrenalectomy; Adrenergic Fibers; Adult; Aged; alpha-Methyltyrosine; Anesthesia; Animals

1987
Changes in contractility fail to alter the size of the functional border zone in anesthetized dogs.
    Circulation research, 1987, Volume: 61, Issue:2

    Topics: Anesthesia; Animals; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Infusions, Intraven

1987
Reversal by hypothermia of vasodilator-induced tachycardia in anesthetized rats.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 288, Issue:2

    Topics: Acetylcholine; Anesthesia; Animals; Blood Pressure; Body Temperature; Diazoxide; Heart Rate; Hydrala

1987
[Non-invasive Doppler-ultrasound determination of cardiac output. Results and experiences with the ACCUCOM].
    Der Anaesthesist, 1987, Volume: 36, Issue:9

    Topics: Aged; Anesthesia; Cardiac Output; Heart Rate; Humans; Isoproterenol; Middle Aged; Thermodilution; Ul

1987
Cardiac arrhythmias in familial amyloid polyneuropathy during anaesthesia.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:4

    Topics: Adult; Aged; Amyloidosis; Anesthesia; Arrhythmias, Cardiac; Autonomic Nervous System Diseases; Brady

1986
Effect of chronic administration of denopamine (TA-064), a new positive inotropic agent, on cardiac response of rats to denopamine.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:1

    Topics: Anesthesia; Animals; Dihydroalprenolol; Drug Tolerance; Ethanolamines; Heart Rate; Isoproterenol; Ma

1986
Involvement of peripheral dopamine receptors in the antihypertensive effect of a new ergoline derivative (355/1057).
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 274, Issue:2

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cats; Dogs; Domperidone; Ergolines; Fe

1985
Inotropic selectivity of salbutamol and terbutaline in anaesthetised, areflexic dogs.
    European journal of pharmacology, 1985, Oct-08, Volume: 116, Issue:1-2

    Topics: Albuterol; Anesthesia; Animals; Butoxamine; Dogs; Female; Heart Rate; Ilium; Isoproterenol; Male; My

1985
The effects of adrenoceptor agonists and antagonists on plasma potassium concentration in anaesthetized guinea-pigs, rabbits and rats.
    British journal of pharmacology, 1985, Volume: 86, Issue:4

    Topics: Anesthesia; Angiotensin II; Animals; Apamin; Blood Pressure; Epinephrine; Ethanolamines; Guinea Pigs

1985
Comparison of three methods for cardiac output determination in cats.
    American journal of veterinary research, 1985, Volume: 46, Issue:12

    Topics: Anesthesia; Animals; Cardiac Output; Cats; Echocardiography; Evaluation Studies as Topic; Female; Is

1985
Effects of denopamine (TA-064), a new positive inotropic agent, on myocardial oxygen consumption and left ventricular dimension in anesthetized dogs.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:2

    Topics: Anesthesia; Animals; Blood Pressure; Cardiotonic Agents; Coronary Circulation; Dogs; Electrocardiogr

1985
Selective beta adrenergic receptor antagonism in the anesthetized dog.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 188, Issue:2

    Topics: Adrenergic beta-Antagonists; Airway Resistance; Anesthesia; Animals; Blood Pressure; Blood Vessels;

1974
Blockade of peripheral vascular responses to isoprenaline by three beta-adrenoceptor antagonists in the anaesthetized dog.
    British journal of pharmacology, 1974, Volume: 51, Issue:2

    Topics: Acetamides; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Dogs; Dose-Response Re

1974
Neurogenic influence on pulmonary compliance.
    The Journal of trauma, 1974, Volume: 14, Issue:2

    Topics: Anesthesia; Animals; Atropine; Body Weight; Craniocerebral Trauma; Electric Stimulation; Haplorhini;

1974
[Evaluation of myocardial contractility using simultaneous recording of left ventricular pressure and apex cardiogram].
    Archives des maladies du coeur et des vaisseaux, 1974, Volume: 67, Issue:4

    Topics: Anesthesia; Animals; Cardiac Catheterization; Dogs; Electrocardiography; Heart; Hemodynamics; Isopro

1974
[Influence of respiratory acidosis on the cardio-accelerative effect of catecholamines].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1970, Sep-25, Volume: 164, Issue:2

    Topics: Acidosis, Respiratory; Anesthesia; Animals; Dogs; Epinephrine; Female; Heart; Heart Rate; Hydrogen-I

1970
Effects of catecholamines on the gastrocnemius muscle of the domestic fowl.
    European journal of pharmacology, 1968, Volume: 4, Issue:3

    Topics: Anesthesia; Animals; Chickens; Drug Synergism; Epinephrine; Injections, Intravenous; Isoproterenol;

1968
Effects of cold, eating, efferent nerve stimulation and angiotensin on heart rate in sheep before and after autonomic blockade.
    The Journal of physiology, 1971, Volume: 216, Issue:1

    Topics: Anesthesia; Angiotensin II; Animals; Atropine; Autonomic Nerve Block; Cold Temperature; Eating; Elec

1971
Clinical management of the patient in shock. Neurolept analgesia.
    Clinical anesthesia, 1965, Volume: 2

    Topics: Anesthesia; Benperidol; Female; Fentanyl; Humans; Isoproterenol; Middle Aged; Neuroleptanalgesia; Ph

1965
[Influence of hypocapnic gaseous alkalosis on beta effects of sympathomimetics].
    Pathologie-biologie, 1969, Volume: 17, Issue:1

    Topics: Acid-Base Equilibrium; Alkalosis; Anesthesia; Animals; Blood Pressure; Carbon Dioxide; Dogs; Ephedri

1969
A comparison of the effects of (plus of minus)-propranolol and (plus)-propranolol in anaesthetized dogs; beta-receptor blocking and haemodynamic action.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:4

    Topics: Anesthesia; Animals; Cardiac Output; Cardiac Volume; Dogs; Female; Heart; Heart Conduction System; H

1969
[Pharmacological study of phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2 hydrochloride or fenspiride (JP 428)].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:8

    Topics: Anaphylaxis; Anesthesia; Animals; Anti-Inflammatory Agents; Atropine; Autonomic Nervous System; Bron

1969
Hemodynamic effects of phenoxybenzamine in anesthetized dogs.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:11

    Topics: Adrenal Glands; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Cardiac Output; Ca

1970
Analysis of the actions of alprenolol and propranolol on the beta adrenergic receptors controlling heart rate in the anaesthetized cat.
    European journal of pharmacology, 1971, Volume: 14, Issue:4

    Topics: Adrenal Glands; Adrenalectomy; Adrenergic beta-Antagonists; Allyl Compounds; Amino Alcohols; Anesthe

1971
Alteration of renin release by stress and adrenergic receptor and related drugs in unanesthetized rats.
    Advances in experimental medicine and biology, 1972, Volume: 22

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-A

1972
An analysis of the contribution of the endocrine pancreas to the kalemotropic actions of catecholamines.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:2

    Topics: Anesthesia; Animals; Catecholamines; Dogs; Epinephrine; Insulin; Insulin Antagonists; Iodine Radiois

1974
Facial vasomotor behaviour.
    British journal of anaesthesia, 1974, Volume: 46, Issue:10

    Topics: Adolescent; Adult; Anesthesia; Cheek; Face; Female; Fingers; Halothane; Humans; Isoproterenol; Male;

1974
Studies on the mechanism of hydrocortisone potentiation of vasoconstrictor responses to epinephrine in the anesthetized animal.
    European journal of pharmacology, 1972, Volume: 20, Issue:1

    Topics: Acetylcholine; Anesthesia; Animals; Blood Pressure; Cats; Cocaine; Denervation; Dogs; Dose-Response

1972
Proceedings: The influence of adrenergic drugs on intraocular pressure in the anaesthetized dog.
    Experimental eye research, 1973, Nov-25, Volume: 17, Issue:4

    Topics: Anesthesia; Animals; Blood Pressure; Dogs; Epinephrine; Intraocular Pressure; Isoproterenol; Norepin

1973
Correlation of maximum aortic and carotid flow acceleration in chronically instrumented dogs.
    Circulation research, 1974, Volume: 34, Issue:3

    Topics: Acetylcholine; Anesthesia; Animals; Aorta; Blood Flow Velocity; Cardiac Catheterization; Carotid Art

1974
[Orthotopic homotransplantation of the heart in the dog. Technical problems and cardiac resuscitation problems].
    Minerva chirurgica, 1971, Jun-15, Volume: 26, Issue:11

    Topics: Anesthesia; Animals; Assisted Circulation; Dogs; Extracorporeal Circulation; Heart Transplantation;

1971
The arrhythmogenic action of sympathomimetic amines.
    European journal of pharmacology, 1968, Volume: 3, Issue:1

    Topics: Amino Alcohols; Anesthesia; Animals; Arrhythmias, Cardiac; Cats; Electroshock; Epinephrine; Ergoloid

1968
Quindonium bromide: cardiac rate and rhythm disturbances in barbiturate. Anesthetized dogs.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 181, Issue:1

    Topics: Anesthesia; Animals; Barbiturates; Blood Pressure; Carotid Sinus; Denervation; Dogs; Electric Stimul

1972
Cardiac arrhythmias in anesthesia and in acute myocardial infarction.
    International anesthesiology clinics, 1972,Spring, Volume: 10, Issue:1

    Topics: Anesthesia; Arrhythmias, Cardiac; Atropine; Bradycardia; Digitalis Glycosides; Electrocardiography;

1972
Comparison of some effects of glucagon and isoprenaline on the cardiovascular system of the anaesthetized dog.
    British journal of anaesthesia, 1972, Volume: 44, Issue:5

    Topics: Anesthesia; Animals; Blood Pressure; Cardiac Output; Cardiac Volume; Dogs; Electric Stimulation; Ele

1972
[Potentiation of thiopental anesthesia by adrenaline].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:3

    Topics: Anesthesia; Animals; Blood Proteins; Brain; Brain Chemistry; Drug Synergism; Epinephrine; Fatty Acid

1971
Free fatty acids and oxygen consumption in dogs.
    Scandinavian journal of clinical and laboratory investigation, 1971, Volume: 28, Issue:2

    Topics: Anesthesia; Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dogs; Fasting; Fatty Acids

1971
Central mechanisms of vomiting related to catecholamine response: anaesthetic implication.
    Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:4

    Topics: Anesthesia; Animals; Basal Ganglia; Brain; Catecholamines; Cats; Cerebral Ventricles; Electrodes, Im

1971
Potentiation of barbiturate anesthesia by catecholamines.
    Japanese journal of pharmacology, 1967, Volume: 17, Issue:2

    Topics: Anesthesia; Animals; Barbiturates; Catecholamines; Drug Synergism; Epinephrine; Hexobarbital; Inject

1967
The influence of propranolol on cardiovascular function in conscious and anaesthetized horses.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 180, Issue:1

    Topics: Anesthesia; Animals; Cardiovascular System; Drug Antagonism; Epinephrine; Halothane; Heart Rate; Hor

1969
Effect of isopropylamino radical and isoquinoline derivatives on cardiovascular system.
    Japanese circulation journal, 1969, Volume: 33, Issue:6

    Topics: 1-Propanol; Anesthesia; Animals; Blood Pressure; Cardiovascular System; Depression, Chemical; Dogs;

1969
[Experimental and clinical studies on the effects of tetrahydroisoquinoline derivatives on the respiratory and circulatory systems].
    Masui. The Japanese journal of anesthesiology, 1967, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia; Animals; Blood Circulation; Bronchial Diseases; Dogs; Female; H

1967
[Short-term narcosis and laryngospasm].
    Minerva anestesiologica, 1968, Volume: 34, Issue:7

    Topics: Adenoidectomy; Adolescent; Adult; Anesthesia; Angiocardiography; Child; Child, Preschool; Humans; Is

1968
[Indications and effects of isoproterenol in anesthesia].
    Masui. The Japanese journal of anesthesiology, 1968, Volume: 17, Issue:5

    Topics: Adolescent; Aged; Anesthesia; Animals; Blood Circulation; Chemical Phenomena; Chemistry; Child; Coro

1968
[Do catecholamines increase basal metabolism?].
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:6

    Topics: Anesthesia; Animals; Basal Metabolism; Blood Pressure; Body Temperature; Calorimetry; Curare; Epinep

1968
The responses of cortical neurones to monoamines under differing anaesthetic conditions.
    The Journal of physiology, 1969, Volume: 203, Issue:2

    Topics: Acetylcholine; Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Barbiturates; C

1969
Hepatic circulation and hepatic function during anaesthesia and surgery. IV. Halothane anaesthesia.
    Canadian Anaesthetists' Society journal, 1966, Volume: 13, Issue:4

    Topics: Acidosis; Anesthesia; Animals; Blood Flow Velocity; Blood Pressure; Carbon Dioxide; Chloroform; Dogs

1966