Page last updated: 2024-10-29

isoproterenol and Airway Hyper-Responsiveness

isoproterenol has been researched along with Airway Hyper-Responsiveness in 25 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Research Excerpts

ExcerptRelevanceReference
" The possible acute occurrence of airway hyperreactivity after immediate-type bronchial anaphylaxis has been investigated in anaesthetized guinea-pigs actively sensitized to ovalbumin (OA)."3.67Immediate anaphylactic bronchoconstriction induces airway hyperreactivity in anaesthetized guinea-pigs. ( Daffonchio, L; Lees, IW; Payne, AN; Whittle, BJ, 1988)
" Intratracheal administration of IL-1beta or chronic administration of albuterol significantly decreased (p < 0."1.30An in vivo model of beta-adrenoceptor desensitization. ( Agrawal, DK; Chong, BT; Romero, FA; Townley, RG, 1998)
" Isometric tension was measured and dose-response curves were constructed for levcromakalim (a KATP opener), Y-26763 (another KATP opener), isoprenaline and theophylline in guinea-pig isolated trachea that was challenged with ovalbumin or pretreated in vitro with either isoprenaline or the KATP openers."1.29Allergic responses reduce the relaxant effect of beta-agonists but not potassium channel openers in guinea-pig isolated trachea. ( Dobashi, K; Houjou, S; Iizuka, K; Nakazawa, T, 1996)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199018 (72.00)18.7374
1990's5 (20.00)18.2507
2000's0 (0.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matusovsky, OS1
Kachmar, L1
Ijpma, G1
Panariti, A1
Benedetti, A1
Martin, JG1
Lauzon, AM1
Jo-Avila, MJ1
Al-Jumaily, AM1
MITSUSE, J1
Shelhamer, JH1
Marom, Z1
Kaliner, M1
Jolobe, OM2
Meurs, H1
Koëter, GH1
de Vries, K1
Kauffman, HF1
Rola-Pleszczynski, M1
Blanchard, R1
Brink, C1
Duncan, PG1
Midzenski, M1
Douglas, JS1
Houjou, S1
Iizuka, K1
Dobashi, K1
Nakazawa, T1
Chong, BT1
Agrawal, DK1
Romero, FA1
Townley, RG2
Schmidt, D1
Ruehlmann, E1
Branscheid, D1
Magnussen, H1
Rabe, KF1
McGeady, S1
Bewtra, A1
Butcher, BT1
Salvaggio, JE1
O'Neil, CE1
Weill, H1
Garg, O1
Webb-Johnson, DC1
Andrews, JL1
Mazzoni, L1
Chapman, ID2
Morley, J2
Boubekeur, K1
Engels, F1
Folkerts, G1
van Heuven-Nolsen, D1
Nijkamp, FP1
Daffonchio, L1
Payne, AN1
Lees, IW1
Whittle, BJ1
Hay, DW1
Raeburn, D1
Farmer, SG1
Fleming, WW1
Fedan, JS1
Rachelefsky, GS1
Osher, A1
Dooley, RE1
Ank, B1
Stiehm, ER1
Rowe, AH1
Rowe, A1
Sinclair, C1
Franz, T1
McMurrain, KD1
Brooks, S1
Bernstein, IL1
Balbi, L1
Dolcetti, A1
Motta, PE1
Gaino, T1
Schlueter, DP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005280]0 participants Observational1972-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for isoproterenol and Airway Hyper-Responsiveness

ArticleYear
Airway eosinophilia and airway hyperreactivity are parallel rather than sequential events in the guinea-pig.
    Agents and actions. Supplements, 1991, Volume: 34

    Topics: Allergens; Animals; Asthma; Cytokines; Eosinophilia; Eosinophils; Guinea Pigs; Humans; Isoproterenol

1991

Other Studies

24 other studies available for isoproterenol and Airway Hyper-Responsiveness

ArticleYear
Contractile Properties of Intrapulmonary Airway Smooth Muscle in Cystic Fibrosis.
    American journal of respiratory cell and molecular biology, 2019, Volume: 60, Issue:4

    Topics: Adult; Asthma; Bronchoconstrictor Agents; Bronchodilator Agents; Cystic Fibrosis; Cystic Fibrosis Tr

2019
Superimposed pressure oscillations: An alternative to treat airway hyperresponsiveness in an acute sensitized airways mouse model.
    Respiratory physiology & neurobiology, 2017, Volume: 238

    Topics: Acetylcholine; Acute Disease; Animals; Bronchodilator Agents; Disease Models, Animal; Female; Isopro

2017
[RECURRENCE OF BRONCHIAL ASTHMA, FACTORS CAUSING EXACERBATION AND THERAPY].
    [Sogo rinsho] Clinic all-round, 1963, Volume: 12

    Topics: Aminophylline; Anti-Allergic Agents; Asthma; Autonomic Nervous System Diseases; Ephedrine; Epinephri

1963
Abnormal beta-adrenergic responsiveness in allergic subjects. II. The role of selective beta 2-adrenergic hyporeactivity.
    The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:1 Pt 1

    Topics: Adrenergic beta-Agonists; Adult; Blood Pressure; Female; Heart Rate; Humans; Isoproterenol; Male; Re

1983
Reversible airflow obstruction: clinical spectrum and responsiveness to anticholinergic drugs.
    Respiration; international review of thoracic diseases, 1984, Volume: 45, Issue:3

    Topics: Adult; Aged; Airway Resistance; Albuterol; Asthma; Atropine Derivatives; Bronchitis; Female; Forced

1984
Asthma vs. non-specific reversible airflow obstruction: clinical features and responsiveness to anticholinergic drugs.
    Respiration; international review of thoracic diseases, 1984, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Aged; Airway Resistance; Albuterol; Asthma; Atropine Derivatives; Bronchial Provo

1984
Dynamics of the lymphocyte beta-adrenoceptor system in patients with allergic bronchial asthma.
    European journal of respiratory diseases. Supplement, 1984, Volume: 135

    Topics: Adenylyl Cyclases; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Cell Membrane; Dihydroalp

1984
Suppressor cell function in respiratory allergy. Modulation by aminophylline and isoproterenol.
    International archives of allergy and applied immunology, 1981, Volume: 64, Issue:4

    Topics: Adolescent; Adult; Aminophylline; Child; Child, Preschool; Concanavalin A; Humans; Immunoglobulin E;

1981
Response and sensitivity of female guinea-pig respiratory tissues to agonists during ontogenesis.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:2

    Topics: Age Factors; Aging; Albuterol; Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomet

1980
Allergic responses reduce the relaxant effect of beta-agonists but not potassium channel openers in guinea-pig isolated trachea.
    The European respiratory journal, 1996, Volume: 9, Issue:10

    Topics: Adrenergic beta-Agonists; Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Dose-Response Rel

1996
An in vivo model of beta-adrenoceptor desensitization.
    Journal of pharmacological and toxicological methods, 1998, Volume: 40, Issue:2

    Topics: Administration, Inhalation; Adrenergic beta-Agonists; Albuterol; Animals; Asthma; Bronchoconstrictor

1998
Passive sensitization of human airways increases responsiveness to leukotriene C4.
    The European respiratory journal, 1999, Volume: 14, Issue:2

    Topics: Adult; Aged; Allergens; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Carbachol; Dose-Re

1999
The effect of beta adrenergic blockade on bronchial sensitivity to acetyl-beta-methacholine in normal and allergic rhinitis subjects.
    The Journal of allergy and clinical immunology, 1976, Volume: 57, Issue:4

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Bronchi; Forced Expiratory Volume; Humans; Isoproter

1976
Toluene diisocyanate pulmonary disease: immunopharmacologic and mecholyl challenge studies.
    The Journal of allergy and clinical immunology, 1977, Volume: 59, Issue:3

    Topics: Administration, Intranasal; Aerosols; Cyanates; Cyclic AMP; Histamine Release; Isoproterenol; Lympho

1977
Drug therapy: Bronchodilator therapy (first of two parts).
    The New England journal of medicine, 1977, Sep-01, Volume: 297, Issue:9

    Topics: Adrenergic beta-Agonists; Adult; Bronchi; Bronchial Spasm; Bronchodilator Agents; Cyclic AMP; Cyclic

1977
Changes in airway sensitivity to histamine are not necessarily paralleled by changed sensitivity to acetylcholine.
    Agents and actions. Supplements, 1991, Volume: 34

    Topics: Acetylcholine; Airway Obstruction; Airway Resistance; Animals; Guinea Pigs; Histamine; Injections, I

1991
Haemophilus influenzae-induced decreases in lung beta-adrenoceptor function and number coincide with decreases in spleen noradrenaline.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:3

    Topics: Airway Resistance; Animals; Carbachol; Dihydroalprenolol; Guinea Pigs; Haemophilus influenzae; Isopr

1987
Immediate anaphylactic bronchoconstriction induces airway hyperreactivity in anaesthetized guinea-pigs.
    British journal of pharmacology, 1988, Volume: 94, Issue:3

    Topics: Airway Resistance; Anaphylaxis; Animals; Bronchi; Guinea Pigs; Isoproterenol; Lung; Male; Neutrophil

1988
Epithelium modulates the reactivity of ovalbumin-sensitized guinea-pig airway smooth muscle.
    Life sciences, 1986, Jun-30, Volume: 38, Issue:26

    Topics: Animals; Epithelium; Guinea Pigs; Histamine; Immunization; Isoproterenol; Male; Methacholine Chlorid

1986
Coexistent respiratory allergy and cystic fibrosis.
    American journal of diseases of children (1960), 1974, Volume: 128, Issue:3

    Topics: Adolescent; Adult; Airway Obstruction; Asthma; California; Child; Child, Preschool; Cystic Fibrosis;

1974
Bronchial asthma in infants and children due to food and inhalant allergies.
    The Journal of asthma research, 1967, Volume: 4, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aminophylline; Asthma; Bronchodila

1967
Clinical, immunologic, and physiologic observations in factory workers exposed to B. subtilis enzyme dust.
    The Journal of allergy, 1971, Volume: 47, Issue:3

    Topics: Adult; Bacillus subtilis; Bronchi; Carbon Monoxide; Detergents; Diffusion; Dust; Environmental Expos

1971
[Dynamic pulmonary non-elastic resistance and compliance in the various phases of the Altounyan test].
    Minerva medica, 1970, Mar-17, Volume: 61, Issue:22

    Topics: Adult; Asthma; Atropine; Bronchitis; Diagnosis, Differential; Elasticity; Female; Humans; Isoprotere

1970
Diagnosis and treatment of hypersensitivity pneumonitis.
    Medical times, 1970, Volume: 98, Issue:11

    Topics: Acute Disease; Animals; Bronchodilator Agents; Chronic Disease; Columbidae; Corticosterone; Dust; Hu

1970