isoproterenol has been researched along with Aging in 515 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Long non-coding RNA myocardial infarction associated transcript (LncMIAT) is closely related to heart disease, and here, we were the first to discover that LncMIAT may act as an miR-144 sponge in isoproterenol-induced cardiac hypertrophy." | 7.96 | The Expression of microRNA in Adult Rat Heart with Isoproterenol-Induced Cardiac Hypertrophy. ( Bai, L; Chen, L; Fan, Y; Gan, M; Guo, Z; Hao, X; Jiang, D; Li, X; Shen, L; Tan, Y; Zhang, S; Zhu, L, 2020) |
| "The diagnosis of neuromediated syncope is often established with isoproterenol head-up tilt-table testing." | 7.69 | Effects of aging on responses to isoproterenol tilt-table testing in patients with syncope. ( Sheldon, R, 1994) |
| "Prolonged beta-adrenergic stimulation obtained by subcutaneous injection of isoproterenol in unanesthetized, unrestrained rats elicited ventricular fibrillation in approximately 80% of animals at 10-12 months of age." | 7.67 | Increased incidence of isoproterenol-induced ventricular fibrillation in aging rats. ( Anversa, P; Guideri, G; Hiler, B; Olivetti, G; Ricci, R, 1987) |
| " A histological analysis revealed that chronic intake of MEL diminished the age-dependent changes in the structure of muscle fibers of the left ventricle, muscle fiber swelling, and injury zones characteristic of acute cardiac failure caused by ISO." | 5.48 | Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. ( Akatov, V; Baburina, Y; Fadeeva, I; Krestinina, O; Kruglov, A; Odinokova, I; Sotnikova, L; Zvyagina, A, 2018) |
| " Dose-response curves for bradykinin were constructed using the dorsal hand vein compliance technique in veins preconstricted with phenylephrine in 27 volunteers (16 male, 11 female) aged 18 to 81 years." | 5.28 | Bradykinin-induced venodilation is not impaired with aging in humans. ( Blaschke, TF; Dachman, WD; Ford, GA; Hoffman, BB, 1992) |
| "These results show that, in humans, hypertension does not lead to a decrease in chronotropic responses to infusion of the beta-agonist isoproterenol and causes only a modest decrease in left ventricular responses." | 5.08 | Age, hypertension, and cardiac responses to beta-agonist in humans. ( Fourney, A; Leenen, FH; White, M, 1998) |
| " Long non-coding RNA myocardial infarction associated transcript (LncMIAT) is closely related to heart disease, and here, we were the first to discover that LncMIAT may act as an miR-144 sponge in isoproterenol-induced cardiac hypertrophy." | 3.96 | The Expression of microRNA in Adult Rat Heart with Isoproterenol-Induced Cardiac Hypertrophy. ( Bai, L; Chen, L; Fan, Y; Gan, M; Guo, Z; Hao, X; Jiang, D; Li, X; Shen, L; Tan, Y; Zhang, S; Zhu, L, 2020) |
| " However, Mstn-/- mice responded better to isoproterenol stress tests with greater increases in fractional shortening and ejection fraction-differences that were again more apparent in females and which are consistent with physiological cardiac hypertrophy." | 3.78 | The aging myostatin null phenotype: reduced adiposity, cardiac hypertrophy, enhanced cardiac stress response, and sexual dimorphism. ( Garikipati, DK; Jackson, MF; Luong, D; Nelson, OL; Rodgers, BD; Stanton, JB; Vang, DD, 2012) |
| "Isolated perfused hearts from young (3-5 months) and aging (24-25 months) rats were subjected to 60 min of 50% coronary flow reduction and 30 min of isoproterenol (Iso) stimulation starting at 30 min of ischemia." | 3.73 | Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury. ( Gao, F; Grunwald, Z; Hu, A; Li, D; Liu, H; Ma, XL; Qu, Y; Sharifi-Azad, S; Sun, JZ; Tao, L, 2006) |
| "To determine if centrally reducing sympathetic tone with clonidine will reverse the downregulation in the alpha-adrenergic (alphaAR) and beta-adrenergic (betaAR) responses seen with normal aging." | 3.73 | Normal aging impairs upregulation of the beta-adrenergic but not the alpha-adrenergic response: aging and adrenergic upregulation. ( Levy, WC; Madden, KM; Stratton, JR, 2006) |
| "The diagnosis of neuromediated syncope is often established with isoproterenol head-up tilt-table testing." | 3.69 | Effects of aging on responses to isoproterenol tilt-table testing in patients with syncope. ( Sheldon, R, 1994) |
| " The effects of aging on the responsiveness of the isolated pacemaker of the rat to the chronotropic effect of norepinephrine, isoproterenol and soterenol were studied." | 3.68 | Subsensitivity to beta-adrenoceptor agonists in pacemakers isolated from senescent rats. ( de Moraes, S; Spadari, RC, 1991) |
| " The effects of isoproterenol (ISP) and chemical sympathectomy (6-hydroxydopamine treatment) on myocardial beta-receptors were also investigated in 10 and 24 week-old SHRS and WKY to examine the effects of hypertension and aging on receptor regulation." | 3.68 | Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP. ( Ikawa, H; Suzuki, A, 1991) |
| "Cardiac aging is characterized by a reduced heart rate response to beta-agonist stimulation with isoproterenol, but whether the ejection fraction and other cardiovascular responses are reduced in humans is largely unknown." | 3.68 | Differences in cardiovascular responses to isoproterenol in relation to age and exercise training in healthy men. ( Abrass, IB; Cerqueira, MD; Kahn, SE; Levy, WC; Schwartz, RS; Stratton, JR; Veith, RC, 1992) |
| "We determined the effects of D-fenfluramine treatment on the changes in vascular reactivity induced by aging." | 3.68 | Effect of aging and drug-induced weight reduction on rat vascular reactivity. ( Boulanger, M; Duhault, J; Feletou, M; Moreau, N, 1993) |
| "Passive head-up tilt testing with or without infusion of isoproterenol is used in the investigation and management of patients with syncope." | 3.68 | Head-up tilt testing with and without isoproterenol infusion in healthy subjects of different ages. ( Lurie, K; Newman, D; Rosenqvist, M; Scheinman, MM; Schwartz, J; Washington, C, 1993) |
| "The ability of the muscarinic receptor agonist, carbachol, to inhibit beta-adrenergic activation of adenylate cyclase was examined in cardiac membranes from 6-month (young adult) and 24-month (aged) old rats in an effort to assess the effect of aging on adrenergic-cholinergic interactions in the heart." | 3.67 | Autonomic interactions in the aging heart: age-associated decrease in muscarinic cholinergic receptor mediated inhibition of beta-adrenergic activation of adenylate cyclase. ( Narayanan, N; Tucker, L, 1986) |
| "To study potential cardiac receptor alterations during the development of spontaneous hypertension, specific binding of [3H]-2-N(2,6-dimethoxyphenoxyethyl)amino-methyl-1,4-benzodioxane, (-)-[3H]dihydroalprenolol and (-)-[3H]quinuclidinyl benzilate in ventricles of Wistar Kyoto rats (WKY), spontaneously hypertensive rats (SHR) and stroke-prone SHR (SHRSP) at different ages was determined." | 3.67 | Alterations in cardiac alpha and beta adrenoceptors during the development of spontaneous hypertension. ( Hayashi, E; Hayashi, M; Ishima, T; Okada, T; Tomita, T; Yamada, S, 1984) |
| "To elucidate the association of beta-adrenergic receptors with decreased myocardial catecholamine responsiveness in aging, we investigated the chronotropic response to isoproterenol and myocardial beta-adrenergic receptors in Fisher 344 rats of 3, 12, and 24 months of age." | 3.66 | Isoproterenol responsiveness and myocardial beta-adrenergic receptors in young and old rats. ( Abrass, IB; Davis, JL; Scarpace, PJ, 1982) |
| "Isoproterenol alone was infused in 14 young subjects (age, 30 +/- 2 years) and 15 older healthy volunteers (age, 60 +/- 2 years) and together with ganglionic blockade (trimethaphan) in eight young and eight older subjects." | 2.67 | Aging and cardiovascular responsiveness to beta-agonist in humans: role of changes in beta-receptor responses versus baroreflex activity. ( Leenen, FH; White, M, 1994) |
| " A histological analysis revealed that chronic intake of MEL diminished the age-dependent changes in the structure of muscle fibers of the left ventricle, muscle fiber swelling, and injury zones characteristic of acute cardiac failure caused by ISO." | 1.48 | Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. ( Akatov, V; Baburina, Y; Fadeeva, I; Krestinina, O; Kruglov, A; Odinokova, I; Sotnikova, L; Zvyagina, A, 2018) |
| "While Huntington's disease (HD) is classified as a neurological disorder, HD patients exhibit a high incidence of cardiovascular events leading to heart failure and death." | 1.43 | Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease. ( Colwell, CS; Coppola, G; Fishbein, MC; Gao, F; Ghiani, CA; Jordan, MC; Park, S; Roos, KP; Schroeder, AM; Wang, HB, 2016) |
| "Isoproterenol (10(-4)M) was infused for 20 min, 4h 10 min after the beginning of the perifusion." | 1.33 | Old rats are more sensitive to photoperiodic changes. A study on pineal melatonin. ( Charbuy, H; Djeridane, Y; Touitou, Y, 2005) |
| "isoproterenol were not reduced in 24-m." | 1.33 | Differential effects of aging on fluid intake in response to hypovolemia, hypertonicity, and hormonal stimuli in Munich Wistar rats. ( Denton, DA; Mathai, ML; McKinley, MJ; Thomas, CJ; Woods, RL, 2006) |
| "Ventricular tachyarrhythmias were initiated in TG mice by programmed stimulation but not in WT and were accelerated by isoproterenol." | 1.32 | Electrophysiological consequences of human IKs channel expression in adult murine heart. ( Cabo, C; Chiello Tracy, C; Coromilas, J; Kass, RS; Kurokawa, J; Wit, AL, 2003) |
| "Treatment with isoproterenol on PN2-5 did not result in any significant changes in G(s)alpha expression but robustly decreased G(i)alpha1,2." | 1.31 | Ontogeny of G-protein expression: control by beta-adrenoceptors. ( Seidler, FJ; Slotkin, TA; Zeiders, JL, 2000) |
| "Nicotine is a neuroteratogen that targets synaptic function during critical developmental stages and recent studies indicate that CNS vulnerability extends into adolescence, the age at which smoking typically commences." | 1.31 | Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase. ( Cousins, MM; Seidler, FJ; Slikker, W; Slotkin, TA; Xu, Z, 2002) |
| " There was a significant decrease with age in the maximal relaxation to cholera toxin as well as a rightward shift in the dose-response curve." | 1.30 | Impaired cholera toxin relaxation with age in rat aorta. ( Chapman, J; Mader, SL; Schutzer, WE; Watts, VJ, 1999) |
| "Isoproterenol pretreatment failed to cause beta-receptor down-regulation in 6-d-old animals, but by 15 d of age, down-regulation was detected along with slight desensitization of the cyclase response." | 1.29 | Atypical regulation of hepatic adenylyl cyclase and adrenergic receptors during a critical developmental period: agonists evoke supersensitivity accompanied by failure of receptor down-regulation. ( Galluzzo, JM; McCook, EC; Seidler, FJ; Slotkin, TA; Thai, L, 1996) |
| "Isoproterenol stimulation was reduced markedly in passaged cells." | 1.28 | Beta-adrenergic responsiveness in cultured aorta smooth muscle cells. Effects of subculture and aging. ( Borst, SE; Crass, MF; Scarpace, PJ, 1992) |
| " Dose-response curves for bradykinin were constructed using the dorsal hand vein compliance technique in veins preconstricted with phenylephrine in 27 volunteers (16 male, 11 female) aged 18 to 81 years." | 1.28 | Bradykinin-induced venodilation is not impaired with aging in humans. ( Blaschke, TF; Dachman, WD; Ford, GA; Hoffman, BB, 1992) |
| "coli, a fever was evident in 2." | 1.28 | The association of E. coli peritonitis with an impaired and delayed fever response in senescent rats. ( Bender, BS; Borst, SE; Scarpace, PJ, 1992) |
| " Isoproterenol-stimulated dose-response activation of adenylate cyclase was unchanged between 3 and 12 months but decreased at 24 months (p less than ." | 1.28 | Beta-adrenergic signal transduction in aging parotid and submandibular salivary glands. ( Rajakumar, G; Scarpace, PJ, 1991) |
| "Certain clinical manifestations of Parkinson's disease (PD) (speech or/and balance disturbances) are not linked to brain dopamine deficiency." | 1.28 | Cardiac beta-adrenoceptor sensitivity and Parkinson's disease. ( Allain, H; Bentue-Ferrer, D; Decombe, R; Lemaitre, MH; Martinet, JP; Milon, D, 1991) |
| " Dose-response curves showed that in foetal rat hepatocytes glucose release was already increased by 10(-8) M isoproterenol, whereas in female rat hepatocytes at least 10(-6) M isoproterenol was required." | 1.28 | Differences in the accessibility of the beta-adrenergic receptor in isolated hepatocytes from foetal and adult rats. ( Dettmer, D; Hermsdorf, T; Hofmann, E, 1991) |
| "Isoproterenol (IPR) was given to mice 27 and 29 months old to assess whether levels of mucin could be restored to levels similar to those in younger mice." | 1.28 | Increased mucin levels in submandibular glands of aged male mice after chronic isoproterenol treatment. ( Denny, PA; Denny, PC; Klauser, DK; Villa, BJ, 1991) |
| " This dosage regimen of dexamethasone also suppressed renal cyclic AMP responses to isoproterenol, but exposure to a lower dose (0." | 1.28 | Dose-dependent effect of prenatal dexamethasone treatment on beta-adrenergic receptor coupling to ornithine decarboxylase and cyclic AMP. ( Bartolome, J; Bartolome, M; Bian, XP; Kavlock, RJ; Seidler, FJ; Slotkin, TA, 1990) |
| "Both isoproterenol and ACTH were significantly less effective in promoting cAMP accumulation in adipocytes isolated from 12-mo-old rats." | 1.27 | Age-related decrement in hormone-stimulated lipolysis. ( Chang, H; Farahbakhsh, ZT; Hoffman, BB; Reaven, GM, 1984) |
| "Adenosine deaminase was added to media containing the adipocytes from older rats to remove endogenous adenosine." | 1.27 | Inhibition of lipolysis by adenosine is potentiated with age. ( Chang, H; Farahbakhsh, Z; Hoffman, BB; Reaven, G, 1984) |
| " The dose-response curves were shifted to the right with advancing age, suggesting reduced beta-agonist potency of the maturing tissue." | 1.27 | Postnatal development of beta-adrenergic response in ventricular muscle of the rat heart. ( Vornanen, M, 1988) |
| " Dose-response curves of isoproterenol revealed a progressive increase in the activation constant (Kact) with advancing age." | 1.27 | Age-related reduction of beta-adrenoceptor sensitivity in rat heart occurs by multiple mechanisms. ( Banerjee, SP; Fan, TH, 1985) |
| " Cumulative dose-response curves of plasma cyclic AMP concentration obtained in another group of rats after successive subcutaneous injections of isoproterenol showed that the ED50 value of this drug was higher in SHR than in WKY and increased in a parallel manner in the two strains between 7 and 18 weeks of age (respectively from 0." | 1.27 | Age-related changes of in vivo beta-adrenergic responsiveness in normotensive and spontaneously hypertensive rats. ( Bucher, B; Heitz, C; Stoclet, JC, 1984) |
| "Isoproterenol pretreatment (1 mg/kg s." | 1.27 | Age-dependent changes in electrophysiologic characteristics of fast and slow action potentials in rat papillary muscle. ( Balazs, T; Ehrreich, S; Johnson, G; Kojima, M; Sperelakis, N, 1983) |
| " Results were similar for isoproterenol, although the positive inotropic effect occurred over a wider dosage range for this drug." | 1.27 | Milrinone effects in the isolated immature rabbit heart. ( Ayres, N; Brannon, TS; Fixler, DE; Parrish, MD; Payne, A, 1988) |
| " The release of free acids (FFA) into the incubation medium was measured after addition of increasing concentrations of catecholamines and the dose-response curves were evaluated." | 1.26 | Responsiveness of the trimmed rat subcutaneous adipose tissue beta-receptors to catecholamines in ontogenesis. ( Mourek, J; Mühlbachová, E, 1982) |
| "Isoproterenol was infused in doses of 0." | 1.26 | The comparative hemodynamic effects of isoproterenol in chronically instrumented puppies and adult dogs. ( Driscoll, DJ; Entman, ML; Fukushige, J; Hartley, CJ; Lewis, RM, 1981) |
| "3." | 1.26 | Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the pre-weanling rat. ( Seidler, FJ; Slotkin, TA, 1979) |
| " The mean log dose-response curve for the elderly group was displaced to the right and the mean maximum response was less than that for the young subjects." | 1.26 | Age and beta adrenoceptor-mediated function. ( Chung, S; Dillon, N; Kelly, J; O'Malley, K, 1980) |
| " No age differences were seen in the time course of amylase release following (-)-isoproterenol stimulation or in the (-)-isoproterenol dose-response curve." | 1.26 | Beta-adrenergic regulation of rat parotid gland exocrine protein secretion during aging. ( Baum, BJ; Ito, H; Roth, GS, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 241 (46.80) | 18.7374 |
| 1990's | 190 (36.89) | 18.2507 |
| 2000's | 54 (10.49) | 29.6817 |
| 2010's | 26 (5.05) | 24.3611 |
| 2020's | 4 (0.78) | 2.80 |
| Authors | Studies |
|---|---|
| Yáñez-Bisbe, L | 1 |
| Garcia-Elias, A | 1 |
| Tajes, M | 1 |
| Almendros, I | 1 |
| Rodríguez-Sinovas, A | 1 |
| Inserte, J | 1 |
| Ruiz-Meana, M | 1 |
| Farré, R | 1 |
| Farré, N | 1 |
| Benito, B | 1 |
| Holmuhamedov, EL | 1 |
| Chakraborty, P | 1 |
| Oberlin, A | 1 |
| Liu, X | 1 |
| Yousufuddin, M | 1 |
| Shen, WK | 1 |
| Terzic, A | 1 |
| Jahangir, A | 1 |
| Hardy, CC | 1 |
| Keilich, SR | 1 |
| Harrison, AG | 1 |
| Knight, BE | 1 |
| Baker, DS | 1 |
| Smith, PP | 1 |
| Gan, M | 1 |
| Zhang, S | 1 |
| Fan, Y | 1 |
| Tan, Y | 1 |
| Guo, Z | 1 |
| Chen, L | 1 |
| Bai, L | 1 |
| Jiang, D | 1 |
| Hao, X | 1 |
| Li, X | 1 |
| Shen, L | 1 |
| Zhu, L | 1 |
| Cao, H | 1 |
| Hu, Y | 1 |
| Zhu, X | 1 |
| Yao, N | 1 |
| Gu, J | 1 |
| Wang, Y | 2 |
| Zhu, W | 1 |
| Ulla, A | 1 |
| Mohamed, MK | 1 |
| Sikder, B | 1 |
| Rahman, AT | 1 |
| Sumi, FA | 1 |
| Hossain, M | 1 |
| Reza, HM | 1 |
| Rahman, GMS | 1 |
| Alam, MA | 1 |
| Hardy, RN | 1 |
| Simsek, ZD | 1 |
| Curry, B | 1 |
| Core, SL | 1 |
| Beltz, T | 1 |
| Xue, B | 1 |
| Johnson, AK | 2 |
| Thunhorst, RL | 2 |
| Curtis, KS | 1 |
| Odinokova, I | 1 |
| Baburina, Y | 1 |
| Kruglov, A | 1 |
| Fadeeva, I | 1 |
| Zvyagina, A | 1 |
| Sotnikova, L | 1 |
| Akatov, V | 1 |
| Krestinina, O | 1 |
| Fu, YC | 1 |
| Chen, R | 1 |
| Chen, MY | 1 |
| Chen, Y | 1 |
| Wang, YL | 1 |
| Xu, B | 1 |
| Yang, J | 1 |
| Yin, T | 1 |
| Li, Y | 2 |
| Morgan-Bathke, M | 1 |
| Lin, HH | 1 |
| Chibly, AM | 1 |
| Zhang, W | 1 |
| Sun, X | 1 |
| Chen, CH | 1 |
| Flodby, P | 1 |
| Borok, Z | 1 |
| Wu, R | 1 |
| Arnett, D | 1 |
| Klein, RR | 1 |
| Ann, DK | 1 |
| Limesand, KH | 1 |
| Ross, AJ | 1 |
| Gao, Z | 1 |
| Pollock, JP | 1 |
| Leuenberger, UA | 1 |
| Sinoway, LI | 1 |
| Muller, MD | 1 |
| Carillion, A | 1 |
| Feldman, S | 1 |
| Jiang, C | 1 |
| Atassi, F | 1 |
| Na, N | 1 |
| Mougenot, N | 1 |
| Besse, S | 1 |
| Hulot, JS | 1 |
| Riou, B | 1 |
| Amour, J | 1 |
| Gonzalez-Valdes, I | 1 |
| Hidalgo, I | 1 |
| Bujarrabal, A | 1 |
| Lara-Pezzi, E | 1 |
| Padron-Barthe, L | 1 |
| Garcia-Pavia, P | 1 |
| Gómez-del Arco, P | 1 |
| Gomez, P | 1 |
| Redondo, JM | 1 |
| Ruiz-Cabello, JM | 1 |
| Jimenez-Borreguero, LJ | 1 |
| Enriquez, JA | 1 |
| de la Pompa, JL | 1 |
| Hidalgo, A | 1 |
| Gonzalez, S | 1 |
| Fernandois, D | 1 |
| Na, E | 1 |
| Cuevas, F | 1 |
| Cruz, G | 1 |
| Lara, HE | 1 |
| Paredes, AH | 1 |
| Schroeder, AM | 1 |
| Wang, HB | 1 |
| Park, S | 1 |
| Jordan, MC | 1 |
| Gao, F | 2 |
| Coppola, G | 1 |
| Fishbein, MC | 1 |
| Roos, KP | 1 |
| Ghiani, CA | 1 |
| Colwell, CS | 1 |
| Yaniv, Y | 1 |
| Ahmet, I | 1 |
| Tsutsui, K | 1 |
| Behar, J | 1 |
| Moen, JM | 1 |
| Okamoto, Y | 1 |
| Guiriba, TR | 1 |
| Liu, J | 1 |
| Bychkov, R | 1 |
| Lakatta, EG | 6 |
| Wang, J | 1 |
| Song, Y | 1 |
| Li, H | 1 |
| Shen, Q | 1 |
| Shen, J | 1 |
| An, X | 1 |
| Wu, J | 1 |
| Zhang, J | 2 |
| Wu, Y | 1 |
| Xiao, H | 2 |
| Zhang, Y | 1 |
| Gergs, U | 1 |
| Neumann, J | 1 |
| Simm, A | 1 |
| Silber, RE | 1 |
| Remmers, FO | 1 |
| Läer, S | 1 |
| Bellinger, DL | 1 |
| Silva, D | 1 |
| Millar, AB | 1 |
| Molinaro, C | 1 |
| Ghamsary, M | 1 |
| Carter, J | 1 |
| Perez, S | 1 |
| Lorton, D | 1 |
| Lubahn, C | 1 |
| Araujoa, G | 1 |
| Thyagarajan, S | 1 |
| Mongue-Din, H | 1 |
| Salmon, A | 1 |
| Fiszman, MY | 1 |
| Fromes, Y | 1 |
| Yuan, Q | 1 |
| Han, P | 1 |
| Dong, M | 1 |
| Ren, X | 1 |
| Zhou, X | 1 |
| Chen, S | 1 |
| Jones, WK | 1 |
| Chu, G | 1 |
| Wang, HS | 1 |
| Kranias, EG | 2 |
| Maier, T | 1 |
| Schreckenberg, R | 1 |
| Schlüter, KD | 1 |
| Terrien, J | 1 |
| Ambid, L | 1 |
| Nibbelink, M | 1 |
| Saint-Charles, A | 1 |
| Aujard, F | 1 |
| Salameh, A | 1 |
| Dhein, S | 1 |
| Fleischmann, B | 1 |
| Grohe, C | 1 |
| Hescheler, J | 1 |
| Linz, KW | 1 |
| Meyer, R | 1 |
| Zhang, YY | 1 |
| Du, XJ | 2 |
| Lu, ZZ | 1 |
| Koyanagi, Y | 1 |
| Yamamoto, K | 1 |
| Oi, Y | 1 |
| Koshikawa, N | 1 |
| Kobayashi, M | 1 |
| Sarma, S | 1 |
| Li, N | 1 |
| van Oort, RJ | 1 |
| Reynolds, C | 1 |
| Skapura, DG | 1 |
| Wehrens, XH | 1 |
| Grobe, CL | 1 |
| Beltz, TG | 1 |
| Muscogiuri, G | 1 |
| Kamat, A | 2 |
| Balas, B | 1 |
| Giaccari, A | 1 |
| Defronzo, RA | 1 |
| Musi, N | 1 |
| Katz, MS | 3 |
| Durgan, DJ | 1 |
| Tsai, JY | 1 |
| Grenett, MH | 1 |
| Pat, BM | 1 |
| Ratcliffe, WF | 1 |
| Villegas-Montoya, C | 1 |
| Garvey, ME | 1 |
| Nagendran, J | 1 |
| Dyck, JR | 1 |
| Bray, MS | 1 |
| Gamble, KL | 1 |
| Gimble, JM | 1 |
| Young, ME | 1 |
| Tang, T | 1 |
| Hammond, HK | 1 |
| Firth, A | 1 |
| Yang, Y | 1 |
| Gao, MH | 1 |
| Yuan, JX | 1 |
| Lai, NC | 1 |
| Liles, JT | 1 |
| Ida, KK | 1 |
| Joly, KM | 1 |
| Chapo, J | 1 |
| Plato, CF | 1 |
| Owen, SJ | 1 |
| Massa, HH | 1 |
| Rose'Meyer, RB | 1 |
| Jackson, MF | 1 |
| Luong, D | 1 |
| Vang, DD | 1 |
| Garikipati, DK | 1 |
| Stanton, JB | 1 |
| Nelson, OL | 1 |
| Rodgers, BD | 1 |
| Ghosh, PM | 1 |
| Shu, ZJ | 1 |
| Zhu, B | 1 |
| Lu, Z | 1 |
| Ikeno, Y | 1 |
| Barnes, JL | 1 |
| Yeh, CK | 1 |
| Zhang, BX | 1 |
| Baamonde, C | 1 |
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| MartInez-Cué, C | 1 |
| Vallina, IF | 1 |
| Flórez, J | 1 |
| Dierssen, M | 3 |
| Xu, Z | 1 |
| Seidler, FJ | 9 |
| Cousins, MM | 1 |
| Slikker, W | 1 |
| Slotkin, TA | 12 |
| Chiello Tracy, C | 1 |
| Cabo, C | 1 |
| Coromilas, J | 1 |
| Kurokawa, J | 1 |
| Kass, RS | 1 |
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| Seckin, I | 1 |
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| Hrbasová, M | 1 |
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| Boyden, PA | 1 |
| Djeridane, Y | 2 |
| Khavinson, VKh | 1 |
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| Skelly, RR | 1 |
| Steinberg, AD | 1 |
| Plescia, OJ | 1 |
| Grand, RJ | 1 |
| Schay, MI | 1 |
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| Denckla, WD | 1 |
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| Adelman, RC | 4 |
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| Azain, MJ | 1 |
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| Maeda, N | 1 |
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| Màrmol, F | 2 |
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| Blaschke, TF | 4 |
| Bender, BS | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00005284] | 0 participants | Observational | 1985-01-31 | Completed | |||
| [NCT00005282] | 0 participants | Observational | 1981-12-31 | Completed | |||
| [NCT00005298] | 0 participants | Observational | 1990-07-31 | Completed | |||
| Effects of Insulin on Hypotension and Sarcopenia[NCT03248271] | 0 participants (Actual) | Observational | 2017-10-01 | Withdrawn (stopped due to Study design was changed to the study was changed to Insulin, hypotension and sarcopenia.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for isoproterenol and Aging
| Article | Year |
|---|---|
Beta-adrenergic receptors: biochemical mechanisms of physiological regulation.
Topics: Adenylyl Cyclases; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; A | 1984 |
Sympathetic nervous system and aging in man.
Topics: Adolescent; Adrenal Medulla; Adult; Aged; Aging; Animals; Blood Pressure; Child; Circadian Rhythm; C | 1980 |
Myocardial aging: functional alterations and related cellular mechanisms.
Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Cardiac Glycosides; Cardiomegaly; Coronary Circulat | 1982 |
Adrenoceptor function and ageing.
Topics: Adult; Aged; Aging; Animals; Cyclic AMP; Guinea Pigs; Heart Rate; Humans; In Vitro Techniques; Isopr | 1984 |
Aging and hormone-sensitive lipolysis: reconciling the literature.
Topics: Adenosine; Aging; Animals; Cyclic AMP; Epinephrine; Isoproterenol; Lipolysis; Rats; Rats, Inbred Str | 1994 |
Dynamics of n-3 and n-6 fatty acids in phospholipids of heart muscle.
Topics: Aging; Animals; Animals, Newborn; Catecholamines; Death, Sudden; Dietary Fats; Fatty Acids, Unsatura | 1989 |
11 trials available for isoproterenol and Aging
| Article | Year |
|---|---|
β-Adrenergic receptor blockade impairs coronary exercise hyperemia in young men but not older men.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aging; Coronary Ves | 2014 |
Cardiac sensitivity to isoprenaline, lymphocyte beta-adrenoceptors and age.
Topics: Adult; Aging; Cyclic AMP; Heart Rate; Humans; Isoproterenol; Lymphocytes; Middle Aged; Receptors, Ad | 1984 |
Age-dependent changes in the beta-adrenoceptor-G-protein(s)-adenylyl cyclase system in human right atrium.
Topics: Adenylyl Cyclases; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Blot | 1995 |
Effects of age and hypertension on adrenoceptor-sensitivity evaluated with CD25 and QT/QS2.
Topics: Adult; Aged; Aged, 80 and over; Aging; Electrocardiography; Female; Heart Rate; Humans; Hypertension | 1995 |
Aging and cardiovascular responsiveness to beta-agonist in humans: role of changes in beta-receptor responses versus baroreflex activity.
Topics: Adult; Aged; Aging; Atropine; Baroreflex; Female; Forearm; Heart Rate; Hemodynamics; Humans; Isoprot | 1994 |
Influence of age on venodilator effect of isoproterenol and amrinone.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Amrinone; Blood Pressure; Cross-Ove | 1996 |
Age, hypertension, and cardiac responses to beta-agonist in humans.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Antihypertensive Agents; Blood Pressure; Catecholamine | 1998 |
Effects of age and gender on the cardiovascular responses to isoproterenol.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Cardiovascular System; Female; Humans; Isoproterenol; | 1999 |
Adipose tissue metabolism in young and middle-aged men after control for total body fatness.
Topics: Adipose Tissue; Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists; | 2000 |
Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adult; Aged; Aging; Blood Pressure; Body Composition; Brady | 2002 |
Comparison of hypokalaemic, electrocardiographic and haemodynamic responses to inhaled isoprenaline and salbutamol in young and elderly subjects.
Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Aging; Albuterol; Dose-Response Relation | 1991 |
498 other studies available for isoproterenol and Aging
| Article | Year |
|---|---|
Aging Impairs Reverse Remodeling and Recovery of Ventricular Function after Isoproterenol-Induced Cardiomyopathy.
Topics: Aging; Animals; Cardiomyopathies; Collagen; Disease Models, Animal; Female; Fibrosis; Gene Expressio | 2021 |
Aging-associated susceptibility to stress-induced ventricular arrhythmogenesis is attenuated by tetrodotoxin.
Topics: 4-Aminopyridine; Action Potentials; Aging; Animals; Arrhythmias, Cardiac; Isoproterenol; Male; Myocy | 2022 |
The aging bladder phenotype is not the direct consequence of bladder aging.
Topics: Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Fem | 2019 |
The Expression of microRNA in Adult Rat Heart with Isoproterenol-Induced Cardiac Hypertrophy.
Topics: Aging; Animals; Atrial Natriuretic Factor; Base Sequence; Cardiomegaly; Gene Expression Regulation, | 2020 |
O-GlcNAc transferase affects the signal transduction of β1 adrenoceptor in adult rat cardiomyocytes by increasing the O-GlcNAcylation of β1 adrenoceptor.
Topics: Adenoviridae; Aging; Animals; Calcium; Calcium-Binding Proteins; Cell Death; Cyclic AMP; Cyclic AMP- | 2020 |
Coenzyme Q10 prevents oxidative stress and fibrosis in isoprenaline induced cardiac remodeling in aged rats.
Topics: Aging; Animals; Fibrosis; Isoproterenol; Male; Oxidative Stress; Rats; Rats, Long-Evans; Ubiquinone; | 2017 |
Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Astrocytes; Brain; Drinking; Drinking Water; Female; Isopr | 2018 |
Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Aging; Animals; Calcium; Cell Respiration; Cryoultrami | 2018 |
[Age-related changes in transient outward potassium current of rat ventricular myocyte].
Topics: 4-Aminopyridine; Aging; Animals; Cells, Cultured; Heart Ventricles; Isoproterenol; Myocytes, Cardiac | 2013 |
Deletion of ATG5 shows a role of autophagy in salivary homeostatic control.
Topics: Acinar Cells; Aging; Amylases; Animals; Apoptosis; Aquaporin 5; Autophagy; Autophagy-Related Protein | 2013 |
Overexpression of cyclic adenosine monophosphate effluent protein MRP4 induces an altered response to β-adrenergic stimulation in the senescent rat heart.
Topics: Adrenergic beta-Agonists; Aging; Animals; Arterial Pressure; Bronchodilator Agents; Calcium; Echocar | 2015 |
Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.
Topics: Aging; Animals; Cardiomyopathy, Dilated; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; | 2015 |
Kisspeptin is involved in ovarian follicular development during aging in rats.
Topics: Aging; Animals; Female; Gene Expression; Isoproterenol; Kisspeptins; Ovarian Follicle; Ovary; Ovulat | 2016 |
Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease.
Topics: Adrenergic beta-Agonists; Aging; Animals; Apoptosis; Cardiomegaly; Disease Models, Animal; Fibrosis; | 2016 |
Deterioration of autonomic neuronal receptor signaling and mechanisms intrinsic to heart pacemaker cells contribute to age-associated alterations in heart rate variability in vivo.
Topics: Aging; Animals; Autonomic Nervous System; Carbachol; Heart Rate; Isoproterenol; Longevity; Mice, Inb | 2016 |
Exacerbated cardiac fibrosis induced by β-adrenergic activation in old mice due to decreased AMPK activity.
Topics: Adrenergic beta-Agonists; Aging; AMP-Activated Protein Kinases; Animals; Fibrosis; Heart; Isoprotere | 2016 |
Phosphorylation of phospholamban and troponin I through 5-HT4 receptors in the isolated human atrium.
Topics: Aged; Aging; Atrial Function; Calcium-Binding Proteins; Cyclic AMP; Electric Stimulation; Female; Ge | 2009 |
Sympathetic nervous system and lymphocyte proliferation in the Fischer 344 rat spleen: a longitudinal study.
Topics: 1-Methyl-3-isobutylxanthine; Aging; alpha-Methyltyrosine; Animals; Concanavalin A; Cyclic AMP; Cytok | 2008 |
Periodic variation in R-R intervals and cardiovascular autonomic regulation in young adult Syrian hamsters.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Anti-Arrhythmia Agents; Atrop | 2009 |
Partial downregulation of junctin enhances cardiac calcium cycling without eliciting ventricular arrhythmias in mice.
Topics: Aging; Animals; Arrhythmias, Cardiac; Caffeine; Calcium Signaling; Calcium-Binding Proteins; Disease | 2009 |
Effect of preischemic beta-adrenoceptor stimulation on postischemic contractile dysfunction.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Female; Hemodynamics; Hyperte | 2009 |
Non-shivering thermogenesis activation and maintenance in the aging gray mouse lemur (Microcebus murinus).
Topics: Adaptation, Physiological; Adipose Tissue, Brown; Age Factors; Aging; Animals; Arousal; Blotting, We | 2010 |
The aging heart: changes in the pharmacodynamic electrophysiological response to verapamil in aged rabbit hearts.
Topics: Age Factors; Aging; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Carbachol; Electrop | 2010 |
Developmental changes in the geometry, function and responsiveness of the mouse heart to beta-adrenergic stimulation as determined by high-resolution echocardiography.
Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Echocardiography; Exercise Test; Heart; | 2010 |
Presynaptic interneuron subtype- and age-dependent modulation of GABAergic synaptic transmission by beta-adrenoceptors in rat insular cortex.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Cerebral Cor | 2010 |
Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy.
Topics: Aging; Animals; Calcium; Cardiomyopathies; Cyclic AMP-Dependent Protein Kinases; Death, Sudden; Fibr | 2010 |
Effects of β-adrenergic receptor agonists on drinking and arterial blood pressure in young and old rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Albuterol; Animals; Blood Pressure; Dr | 2011 |
β-Adrenergic Responsive Induction of Insulin Resistance in Liver of Aging Rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Glucose; Insulin; Insulin Resistance; Insulin Secretion; I | 2011 |
Evidence suggesting that the cardiomyocyte circadian clock modulates responsiveness of the heart to hypertrophic stimuli in mice.
Topics: Aging; Animals; Body Temperature; Cardiomegaly; Cardiotonic Agents; Circadian Clocks; CLOCK Proteins | 2011 |
Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged hearts.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Calcium; Calcium-Binding Proteins; Cycl | 2011 |
Age exacerbates chronic catecholamine-induced impairments in contractile reserve in the rat.
Topics: Aging; Animals; Cardiotonic Agents; Catecholamines; Digoxin; Drug Administration Schedule; Isoproter | 2011 |
Loss of adenosine A2B receptor mediated relaxant responses in the aged female rat bladder; effects of dietary phytoestrogens.
Topics: Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Aging; Animals; Carbachol; Diet; Estrog | 2012 |
The aging myostatin null phenotype: reduced adiposity, cardiac hypertrophy, enhanced cardiac stress response, and sexual dimorphism.
Topics: Adipose Tissue, Brown; Adiposity; Aging; Animals; Bone Density; Cardiomegaly; Cardiotonic Agents; Fe | 2012 |
Role of β-adrenergic receptors in regulation of hepatic fat accumulation during aging.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Cells, Cul | 2012 |
Postnatal handling induces long-term modifications in central beta-noradrenergic signalling in rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Cerebellum; | 2002 |
Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Brain Chemistry; Colforsin; Female; GTP | 2002 |
Electrophysiological consequences of human IKs channel expression in adult murine heart.
Topics: Adrenergic beta-Agonists; Aging; Animals; Blood Pressure; Cardiac Pacing, Artificial; Delayed Rectif | 2003 |
Volatile anesthetics and regulation of cardiac Na+/Ca2+ exchange in neonates versus adults.
Topics: Aging; Anesthetics, Inhalation; Animals; Animals, Newborn; Calcium; Halothane; Heart; Heart Ventricl | 2002 |
Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of G(s)alpha protein and deranged signaling of adenylyl cyclase.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Cardiomegaly; Cardiotonic Agents; Colforsin; Fl | 2003 |
Calcium and potassium currents in cells from adult and aged canine right atria.
Topics: Action Potentials; Adrenergic beta-Agonists; Aging; Animals; Barium; Calcium; Calcium Channels; Chel | 2003 |
Effect of a synthetic pineal tetrapeptide (Ala-Glu-Asp-GLy) on melatonin secretion by the pineal gland of young and old rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; In Vitro Techniques; Isoproterenol; Male; Melatonin; Oligo | 2003 |
Gender differences on the effects of aging on cardiac and peripheral adrenergic stimulation in old conscious monkeys.
Topics: Aging; Animals; Colforsin; Consciousness; Dihydropyridines; Female; Isoproterenol; Macaca fascicular | 2003 |
Age-related smooth muscle reactivity changes in the rat bladder: an in vitro study.
Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techni | 2003 |
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
Topics: Adenosine; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Cyclic AMP; Electrophysiolog | 2003 |
The effect of breed, age, and sex on myocardial necrosis produced by isoproterenol in the rat.
Topics: Aging; Animals; Cardiomyopathies; Disease; Heart Diseases; Isoproterenol; Myocardial Infarction; Myo | 1959 |
Developmental differences in L-type calcium current of human atrial myocytes.
Topics: Adolescent; Adrenergic beta-Agonists; Aged; Aging; Calcium Channels, L-Type; Cyclic AMP; Electrophys | 2004 |
Insulin responses to glucose and isoproterenol decrease with age.
Topics: Adrenergic beta-Agonists; Adult; Aging; Female; Glucose; Glucose Clamp Technique; Glucose Intoleranc | 2005 |
Adenylate cyclase-mediated forms of neuronal plasticity in hippocampal area CA1 are reduced with aging.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Aging; Analysis of Variance; Animals; Colf | 2005 |
Old rats are more sensitive to photoperiodic changes. A study on pineal melatonin.
Topics: Adrenergic beta-Agonists; Aging; Animals; Isoproterenol; Male; Melatonin; Photoperiod; Pineal Gland; | 2005 |
Characterization of [3H]-forskolin binding sites in young and adult rat brain cortex: identification of suramin as a competitive inhibitor of [3H]-forskolin binding.
Topics: Adrenergic beta-Agonists; Aging; Animals; Baclofen; Binding, Competitive; Cell Membrane; Cerebral Co | 2005 |
Myocardial dysfunction induced by food restriction is related to morphological damage in normotensive middle-aged rats.
Topics: Aging; Animal Feed; Animals; Body Weight; Calcium; Calcium Chloride; Echocardiography; Food Deprivat | 2005 |
Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury.
Topics: Adrenergic beta-Agonists; Aging; Animals; Isoproterenol; Male; Myocardial Infarction; Myocardial Isc | 2006 |
Synchronous progression of calcium transient-dependent beating and sarcomere destruction in apoptotic adult cardiomyocytes.
Topics: Adrenergic beta-Agonists; Aging; Animals; Apoptosis; Calcium; Calcium Signaling; Cells, Cultured; Is | 2006 |
Effect of recombinant human growth hormone administration on body composition and vascular function and structure in old male Wistar rats.
Topics: Acetylcholine; Adipose Tissue; Aging; Animals; Aorta, Thoracic; Body Composition; Dose-Response Rela | 2005 |
Differential effects of aging on fluid intake in response to hypovolemia, hypertonicity, and hormonal stimuli in Munich Wistar rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Body Weight; Dehydration; Drinking; Eating; Germany; Hypov | 2006 |
Are myocardial eNOS and nNOS involved in the beta-adrenergic and muscarinic regulation of inotropy? A systematic investigation.
Topics: Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cell Size; Cholinergic Agonists; Electric Stimu | 2006 |
Effect of age on vascular beta2-adrenergic receptor desensitization is not mediated by the receptor coupling to Galphai proteins.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Aorta; GTP | 2006 |
Ageing and exercise training alter adrenergic vasomotor responses of rat skeletal muscle arterioles.
Topics: Adrenergic beta-Agonists; Aging; Animals; Arterioles; Colforsin; Enzyme Inhibitors; Hindlimb; Isopro | 2007 |
Normal aging impairs upregulation of the beta-adrenergic but not the alpha-adrenergic response: aging and adrenergic upregulation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Clonidine; Female; Humans; Isoproterenol; Mal | 2006 |
The role of Gi proteins in reduced vasorelaxation response to beta-adrenoceptor agonists in rat aorta during maturation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Aorta; Cyclic AMP | 2007 |
A role for cyclooxygenase in aging-related changes of beta-adrenoceptor-mediated relaxation in rat aortas.
Topics: 6-Ketoprostaglandin F1 alpha; Aging; Animals; Aorta, Thoracic; Aspirin; Immunohistochemistry; Indome | 2007 |
Exercise training and beta-blocker treatment ameliorate age-dependent impairment of beta-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Blood Pres | 2007 |
Dopamine induces apoptosis in young, but not in neonatal, neurons via Ca2+-dependent signal.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Aging; Animals; Apoptosis; Basal Ganglia; | 2007 |
The effects of isoproterenol on abnormal electrical and contractile activity and diastolic calcium are attenuated in myocytes from aged Fischer 344 rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Calcium; Diastole; Electrophysiology; Isoproterenol; Male; | 2007 |
Tonic beta-adrenergic drive provokes proinflammatory and proapoptotic changes in aging mouse heart.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Amidines; Animals; Apoptosis; Benzylam | 2008 |
Age-related changes of in vivo beta-adrenergic responsiveness in normotensive and spontaneously hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Cyclic AMP; Hypertension; Isoproterenol; Male; Propranolol; Rats; Ra | 1984 |
Acute desensitization of lymphocyte beta-adrenergic-stimulated adenylate cyclase in old age and Alzheimer's disease.
Topics: Adenylyl Cyclases; Adult; Aged; Aging; Alzheimer Disease; Cyclic AMP; Female; Humans; In Vitro Techn | 1984 |
Inhibition of lipolysis by adenosine is potentiated with age.
Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Aging; Animals; Isoproterenol; Lipid Mobilization; M | 1984 |
Thymus-endocrine interactions during ageing.
Topics: Aging; Animals; Biological Clocks; Endocrine Glands; Humans; Isoproterenol; Mice; Receptors, Adrener | 1980 |
Contractile and biochemical correlates of beta-adrenergic stimulation of the aged heart.
Topics: Adrenergic beta-Agonists; Aging; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; | 1980 |
Adrenergic and cholinergic mediated glucose oxidation by rat parotid gland acinar cells during aging.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cell Aggregation; Ep | 1981 |
Selected phenotypic induction of null lymphocytes from mice with thymic and nonthymic agents.
Topics: Aging; Animals; Antigens, Surface; Cell Differentiation; Chromosomal Proteins, Non-Histone; Cyclic A | 1982 |
Alterations in cardiac alpha and beta adrenoceptors during the development of spontaneous hypertension.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Dihydroalprenolol; Dioxanes; Heart Ventricles; Hyperte | 1984 |
Alterations in leukocyte beta-receptor affinity with aging. A potential explanation for altered beta-adrenergic sensitivity in the elderly.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Epinephrine; Humans; Isoproterenol; Leukocytes; Male; | 1984 |
Age-related decrement in hormone-stimulated lipolysis.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Aging; Animals; Biomechanical | 1984 |
Beta-adrenergic regulation of rat parotid gland exocrine protein secretion during aging.
Topics: Aging; Amylases; Animals; Dihydroalprenolol; Dose-Response Relationship, Drug; In Vitro Techniques; | 1981 |
[Ultrastructure and metabolic heterogeneity of cardiomyocytes in acute myocardial injury during aging].
Topics: Aging; Animals; Autoradiography; Cardiomyopathies; Histocytochemistry; Isoproterenol; Male; Microsco | 1982 |
Secretion of alpha-amylase from parotid lobules of young and old rats.
Topics: Aging; Amylases; Animals; Isoproterenol; Male; Microscopy, Electron; Parotid Gland; Propranolol; Rat | 1982 |
Effect of clenbuterol, a new beta 2 selective adrenoceptor stimulant, on the release of histamine and SRS-A from passively sensitized guinea-pig chopped lungs.
Topics: Aging; Albuterol; Animals; Chromones; Clenbuterol; Ethanolamines; Guinea Pigs; Histamine Release; In | 1984 |
Effect of aging and cellularity on lipolysis in isolated mouse fat cells.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Aging; Animals; Body Weight; Bucladesine; Epididymis; G | 1980 |
Dual mechanism for inhibition of calcium-dependent action potentials by acetylcholine in avian ventricular muscle. Relationship to cyclic AMP.
Topics: Acetylcholine; Action Potentials; Aging; Animals; Calcium; Catecholamines; Chick Embryo; Cyclic AMP; | 1980 |
Dietary manipulation of age-related decline in vascular smooth muscle function.
Topics: Aging; Animals; Aorta; Food Deprivation; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Va | 1980 |
Age and beta adrenoceptor-mediated function.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Binding Sites; Cyclic AMP; Dose-Response Relationship, | 1980 |
Plasma catecholamines and cardiac, renal and peripheral vascular adrenoceptor-mediated responses in different age groups of normal and hypertensive subjects.
Topics: Adult; Aging; Epinephrine; Heart Rate; Humans; Hypertension; Isoproterenol; Kidney; Middle Aged; Nor | 1980 |
Ontogenetic development of isoproterenol subsensitivity of myocardial adenylate cyclase and beta-adrenergic receptors in spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Aging; Animals; Body Weight; Cell Membrane; Dihydroalprenolol; Heart; Hypertensio | 1980 |
Regulation of protein kinase inhibitor by follicle-stimulating hormone in Sertoli cells in vitro.
Topics: Aging; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Follicle | 1981 |
Age-related elevation of plasma catecholamine concentration and reduced responsiveness of lymphocyte adenylate cyclase.
Topics: Adenylyl Cyclases; Adult; Aging; Cyclic AMP; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Lymph | 1981 |
Human lymphocyte beta-adrenergic receptors are unaltered with age.
Topics: Adolescent; Adult; Aged; Aging; Dihydroalprenolol; Epinephrine; Female; Humans; Isoproterenol; Lymph | 1981 |
The effect of aging on beta-adrenoceptor-stimulated cyclic AMP formation in human lymphocytes.
Topics: Adolescent; Adult; Aged; Aging; Cyclic AMP; Female; Humans; Isoproterenol; Lymphocytes; Male; Stimul | 1981 |
Age-associated decrease of adenylate cyclase activity in rat myocardium.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Female; Guanosine Triphosphat | 1981 |
Quantitative analysis of the lipid-mobilizing effects of corticotropin, beta 1-24--corticotropin (tetracosactide) and isoprenaline in older rats and rabbits.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Aging; Animals; Cosyntropin; Dose-Response Relationship | 1981 |
The development of pre- and postsynaptic components of the noradrenergic system in the rat cerebellum.
Topics: Adenylyl Cyclases; Aging; Animals; Brain; Cerebellum; Dihydroalprenolol; Female; Isoproterenol; Kine | 1981 |
Isoproterenol responsiveness and myocardial beta-adrenergic receptors in young and old rats.
Topics: Aging; Animals; Dihydroalprenolol; Female; Heart Rate; Isoproterenol; Lung; Lymphocytes; Myocardium; | 1982 |
Age-related decrease of in vitro isoproterenol-induced cyclic AMP accumulation in rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Arteries; Cyclic AMP; DNA; Isoproterenol; Male; Muscle Relaxation; | 1982 |
Maturation-related changes in catecholamine-dependent cyclic AMP and protein kinase in the rabbit myocardium.
Topics: Adenylyl Cyclases; Aging; Animals; Catecholamines; Cyclic AMP; Isoproterenol; Myocardium; Phentolami | 1981 |
Responsiveness of the trimmed rat subcutaneous adipose tissue beta-receptors to catecholamines in ontogenesis.
Topics: Adipose Tissue; Aging; Animals; Catecholamines; Epinephrine; Fatty Acids, Nonesterified; Female; In | 1982 |
Beta-receptors during aging in respiratory tissues.
Topics: Aging; Animals; Benzyl Alcohols; Bronchi; Female; Guinea Pigs; Histamine; Isoproterenol; Muscle Rela | 1982 |
Adenylate cyclase and beta adrenergic receptor development in the mouse heart.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Dihydroalprenolol; Female; Fetal Heart; Heart; | 1982 |
Comparison of the effects of age and phorbol myristate acetate on the beta-adrenergic system in mouse epidermis.
Topics: Aging; Animals; Cyclic AMP; Epidermis; Female; Isoproterenol; Mice; Mice, Inbred ICR; Phorbols; Tetr | 1982 |
Decreased beta-adrenergic agonist affinity and adenylate cyclase activity in senescent rat lung.
Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Colforsin; Dihydroalprenolol; Diterpenes; F | 1983 |
Ageing as a factor governing the effect of isoproterenol on the cyclic AMP level in isolated aorta from spontaneously hypertensive and normotensive rats.
Topics: Aging; Animals; Aorta; Cyclic AMP; DNA; Hypertension; In Vitro Techniques; Isoproterenol; Male; Rats | 1983 |
Age-related changes in the control of hepatic cyclic AMP levels by alpha 1- and beta 2-adrenergic receptors in male rats.
Topics: Aging; Animals; Cyclic AMP; Epinephrine; Isoproterenol; Liver; Male; Prazosin; Propranolol; Rats; Ra | 1983 |
Decreased neutrophil cyclic AMP response to isoprenaline stimulation in the elderly.
Topics: Adult; Aged; Aging; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Isoproterenol; Neutrophils | 1983 |
Lymphocyte adenylate cyclase and human aging.
Topics: Adenylyl Cyclases; Adult; Aged; Aging; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; | 1983 |
Beta-adrenergic control of phosphatidylcholine synthesis by transmethylation in hepatocytes from juvenile, adult and adrenalectomized rats.
Topics: Adrenalectomy; Aging; Animals; Cyclic AMP; Ethanolamines; In Vitro Techniques; Insulin; Isoprotereno | 1983 |
Beta-1 and beta-2 adrenoceptor-mediated responses in preparations of pulmonary artery and aorta from young and aged rats.
Topics: Aging; Animals; Aorta; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Tec | 1984 |
[Effect of drugs on cyclic AMP levels in the tissues of animals at different stages of ontogenesis. I. Experimental studies on the effect of adrenomimetic drugs on cyclic AMP concentration in the brain of 7-day-old and adult rats].
Topics: Aging; Animals; Blood-Brain Barrier; Brain; Cyclic AMP; Female; Isoproterenol; Male; Norepinephrine; | 1983 |
Intercellular communication in rat seminiferous tubules.
Topics: Aging; Animals; Calcimycin; Cell Communication; Electrophysiology; Freeze Fracturing; Isoproterenol; | 1983 |
Effects of timed melatonin infusions on reproductive development in the Djungarian hamster (Phodopus sungorus).
Topics: Aging; Animals; Cricetinae; Follicle Stimulating Hormone; Infusions, Parenteral; Isoproterenol; Male | 1984 |
Adenylate cyclase activity in crude plasma membranes of subcutaneous adipocytes during ontogenetic development of rats.
Topics: Adenylyl Cyclases; Adipose Tissue; Aging; Animals; Cell Membrane; Cosyntropin; Female; Guanosine Tri | 1982 |
Ontogenetic studies on adrenergic lipolysis in rat adipocytes from subcutaneous adipose tissue.
Topics: Adipose Tissue; Aging; Animals; Cell Count; Epinephrine; Fatty Acids, Nonesterified; Female; In Vitr | 1982 |
Noradrenergic influences on blocking: interactions with development.
Topics: Aging; Animals; Attention; Avoidance Learning; Conditioning, Operant; Female; Growth; Isoproterenol; | 1984 |
Effect of age on adrenergic neuronal uptake in rat heart.
Topics: Aging; Analysis of Variance; Animals; Catecholamines; Cocaine; Heart Rate; Isoproterenol; Male; Myoc | 1984 |
Age-related changes in sensitivity of rat urinary bladder to autonomic agents.
Topics: Acetylcholine; Aging; Animals; Autonomic Agents; In Vitro Techniques; Isoproterenol; Male; Muscle Co | 1984 |
Effects of age on the adrenergic cardiac neuroeffector junction.
Topics: Aging; Animals; Cardiac Output; Dogs; Epinephrine; Heart; Heart Rate; Humans; Isoproterenol; Nerve E | 1984 |
Depletion of myocardial potassium as a function of age and experimental necrosis.
Topics: Aging; Animals; Female; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Potassium; Rats; | 1984 |
Secretory protein synthesis in parotid glands of young and old rats.
Topics: Aging; alpha-Amylases; Animals; Electrophoresis, Polyacrylamide Gel; Isoproterenol; Male; Parotid Gl | 1983 |
Influence of motor activity on the development of isoprenaline induced heart lesions.
Topics: Aging; Animals; Body Weight; Heart Diseases; Isoproterenol; Male; Motor Activity; Rats; Rats, Inbred | 1983 |
Age-dependent changes in electrophysiologic characteristics of fast and slow action potentials in rat papillary muscle.
Topics: Action Potentials; Aging; Animals; Dose-Response Relationship, Drug; Electrophysiology; In Vitro Tec | 1983 |
Age-dependent alterations in the formation of cyclic nucleotides caused by various agents in guinea-pig tracheal smooth muscle.
Topics: Aging; Animals; Animals, Newborn; Carbachol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; | 1983 |
Higher sensitivity of cerebral arteries isolated from premature and newborn baboons to adrenergic and cholinergic stimulation.
Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Cerebral Arteries; Female; Gestational Age; In Vitr | 1984 |
[Perifusion study of the secretion of calcitonin in the young rat: effect of isoproterenol and theophylline].
Topics: Aging; Animals; Calcitonin; Isoproterenol; Rats; Theophylline; Thyroid Gland | 1981 |
Growth, food intake, motor activity and experimental cardiac necrosis in early malnourished male rats.
Topics: Aging; Animals; Cardiomyopathies; Diet; Growth; Isoproterenol; Male; Motor Activity; Myocardium; Nec | 1982 |
Circulatory effects of chemical sympathectomy in fetal, neonatal, and adult sheep.
Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Blood Pressure; Cardiovascular Physiological Phenom | 1982 |
Catalytic unit of adenylate cyclase: reduced activity in aged-human lymphocytes.
Topics: Adenylyl Cyclases; Adult; Aged; Aging; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosph | 1982 |
Non-developmental modifications induced in submandibular glands of young rats by chronic isoproterenol administration.
Topics: Aging; Animals; Electrophoresis; Isoproterenol; Male; Rats; Salivary Proteins and Peptides; Submandi | 1981 |
Age-related decrease in cardiac and peripheral vascular responsiveness to isoprenaline: studies in normal subjects.
Topics: Adolescent; Adult; Aged; Aging; Blood Pressure; Epinephrine; Female; Forearm; Heart Rate; Humans; Is | 1981 |
Comparative response of the developing canine myocardium to inotropic agents.
Topics: Aging; Animals; Calcium; Dogs; Heart; Isoproterenol; Myocardial Contraction; Ventricular Function | 1982 |
The comparative hemodynamic effects of propranolol in chronically instrumented puppies and adult dogs.
Topics: Aging; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Isoproterenol; Kidne | 1982 |
Age-related changes in pineal "synaptic" ribbon populations in rats exposed to continuous light or darkness.
Topics: Aging; Animals; Darkness; Female; Isoproterenol; Light; Pineal Gland; Propranolol; Rats; Time Factor | 1982 |
Changes in the synthesis of exportable and nonexportable proteins in parotid glands during aging.
Topics: Aging; Animals; Electrophoresis, Polyacrylamide Gel; Isoproterenol; Male; Parotid Gland; Protein Bio | 1982 |
Functional significance of reduced cardiac sympathetic innervation in the newborn dog.
Topics: Adrenalectomy; Aging; Animals; Animals, Newborn; Dogs; Heart; Heart Conduction System; Heart Rate; H | 1982 |
The influences of glucagon, epinephrine and adrenergic agents on glycogen phosphorylase a and pyruvate kinase activities in hepatocytes from juvenile and adult rabbits.
Topics: Aging; Animals; Epinephrine; Glucagon; Isoproterenol; Liver; Male; Phentolamine; Phenylephrine; Phos | 1982 |
[The effect of adrenaline and isoprenaline on calcium level in the plasma of rats of various ages].
Topics: Aging; Animals; Calcium; Epinephrine; Female; Isoproterenol; Male; Rats; Rats, Inbred Strains | 1982 |
The postnatal development of adrenoceptor responses in isolated papillary muscles from rat.
Topics: Aging; Animals; Animals, Newborn; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Norepinep | 1980 |
Secretin and VIP-stimulated adenylate cyclase from rat heart. II. Impairment in spontaneous hypertension.
Topics: Adenylyl Cyclases; Aging; Animals; Brain; Enzyme Activation; Gastrointestinal Hormones; Glucagon; Hy | 1980 |
Morphological response of blood platelets to increased venular permeability in vivo.
Topics: Aging; Animals; Blood Platelets; Cell Membrane Permeability; Eye; Isoproterenol; Male; Rats; Time Fa | 1981 |
Age-dependent changes in the myocardial adenylate cyclase of normotensive and spontaneously hypertensive rat.
Topics: Adenylyl Cyclases; Aging; Animals; Body Weight; Hypertension; Isoproterenol; Male; Microsomes; Muscl | 1981 |
Role of aortic input impedance in the decreased cardiovascular response to exercise with aging in dogs.
Topics: Aging; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dogs; Electric Conductiv | 1981 |
The effect of calcium on the inotropy of catecholamine and paired electrical stimulation in the newborn and adult myocardium.
Topics: Aging; Animals; Animals, Newborn; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; H | 1981 |
Adenylate cyclase activity in the uterine cervix of neonatal and immature mice: influence of oestradiol-17 beta.
Topics: Adenylyl Cyclases; Aging; Animals; Cervix Uteri; DNA; Estradiol; Female; Guanylyl Imidodiphosphate; | 1980 |
Effect of beta adrenergic agents on blood vessels of the rat iris. I. Permeability to carbon particles.
Topics: Aging; Aminophylline; Animals; Capillary Permeability; Carbon; Iris; Isoproterenol; Male; Propanolam | 1980 |
Effect of beta adrenergic agents on blood vessels of the rat iris. II. Morphological modifications of the vessel wall.
Topics: Aging; Animals; Capillary Permeability; Carbon; Endothelium; Iris; Isoproterenol; Male; Microscopy, | 1980 |
Response and sensitivity of female guinea-pig respiratory tissues to agonists during ontogenesis.
Topics: Age Factors; Aging; Albuterol; Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomet | 1980 |
Comparison of the inotropic action of digitalis and isoproterenol in younger and older individuals.
Topics: Adolescent; Adult; Aged; Aging; Digitalis Glycosides; Electrocardiography; Female; Humans; Isoproter | 1980 |
[Stress/strain ratio of the left ventricle in systole. Influence of age and of some drugs (author's transl)].
Topics: Adult; Aged; Aging; Echocardiography; Electrocardiography; Female; Health; Heart; Heart Ventricles; | 1980 |
The comparative hemodynamic effects of isoproterenol in chronically instrumented puppies and adult dogs.
Topics: Aging; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Isoproterenol; Regio | 1981 |
Decreased contractile responses to isoproterenol in isolated cardiac myocytes from aging guinea-pigs.
Topics: Adrenergic beta-Agonists; Aging; Animals; Calcium; Dose-Response Relationship, Drug; Guinea Pigs; He | 1995 |
Age-dependent changes in response of rat prostatic tissues to isoproterenol and forskolin: changes with sexual maturation in function of G proteins.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Cell Nucl | 1995 |
Developmental changes in modulation of calcium currents of rabbit ventricular cells by phosphodiesterase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Animals, Newborn; Calcium; Dose-Response Relationship, | 1994 |
Developmental changes in modulation of contractility of rabbit hearts.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Blood Pressure; Co | 1995 |
G protein alterations in hypertension and aging.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Aging; Aluminum Compoun | 1995 |
Age-related changes in the noradrenergic pattern and receptor responses of the rat cardiovascular system after repeated microwave exposure.
Topics: Aging; Animals; Cardiovascular System; Histocytochemistry; Isoproterenol; Male; Microwaves; Norepine | 1995 |
Effect of ageing and propranolol administration on myocardial beta-adrenoceptor receptor function in mature rats.
Topics: Age Factors; Aging; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Heart; Isoproterenol; Mal | 1995 |
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured; | 1993 |
Effect of aging and drug-induced weight reduction on rat vascular reactivity.
Topics: Administration, Oral; Aging; Animals; Aorta; Blood Glucose; Body Weight; Endothelium, Vascular; Fenf | 1993 |
Head-up tilt testing with and without isoproterenol infusion in healthy subjects of different ages.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Carotid Sinus; Catecholamines; Electrocardiog | 1993 |
Age-dependent alterations in beta-adrenergic responsiveness of rat detrusor smooth muscle.
Topics: Aging; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Electric Stimulation; Isoproteren | 1995 |
Vasomotor reactivity and catecholamine, arginine vasopressin plasma levels during ageing and development in rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Arterial Occlusive Diseases; Blood Pressure; Carotid Artery | 1994 |
The role of adenosine in promoting cardiac beta-adrenergic subsensitivity in aging humans.
Topics: Adenosine; Adult; Aged; Aging; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; | 1995 |
The effects of chronic treatment with N-tert-butyl-alpha-phenylnitrone on cerebellar noradrenergic receptor function in aged F344 rats.
Topics: Aging; Animals; Cerebellum; Cyclic N-Oxides; gamma-Aminobutyric Acid; Isoproterenol; Male; Membrane | 1994 |
Influence of age and gender on skin vessel reactivity to endothelium-dependent and endothelium-independent vasodilators tested with iontophoresis and a laser Doppler perfusion imager.
Topics: Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anesthetics, Local; Endothelium, V | 1995 |
Norepinephrine and posttraining memory consolidation in neonatal rats.
Topics: Aging; Animals; Animals, Newborn; Appetitive Behavior; Association Learning; Brain; Conditioning, Cl | 1994 |
Beta-adrenergic effects on left ventricular filling: influence of aging and exercise training.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Coronary Circulation; D | 1994 |
Expression of beta 1- and beta 3-adrenergic-receptor messages and adenylate cyclase beta-adrenergic response in bovine perirenal adipose tissue during its transformation from brown into white fat.
Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Adrenergic beta-Agonists; Aging; Amino Aci | 1994 |
Age-related changes in DNA synthesis stimulated by epinephrine and isoproterenol in primary cultured rat hepatocytes.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals; Cells, Cultured; DNA; Epi | 1994 |
Atypical beta-adrenergic receptors in rat liver: evidence for transient expression during aging.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Isoproterenol; Liver; Male; Propanol | 1994 |
Beta-adrenergic regulation of action potentials and automaticity in young and adult canine purkinje fibers.
Topics: Action Potentials; Adrenergic beta-Antagonists; Aging; Albuterol; Animals; Cardiac Pacing, Artificia | 1994 |
Age-related changes in the response of the rat urinary bladder to neurotransmitters.
Topics: Aging; Animals; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Neur | 1993 |
Noradrenergic innervation and receptor responses of cardiovascular tissues from young and aged rats after acute microwave exposure.
Topics: Aging; Animals; Aorta, Abdominal; Cardiovascular System; Dose-Response Relationship, Radiation; Envi | 1994 |
Electrophysiological basis for the enhanced cardiac arrhythmogenic effect of isoprenaline in aged spontaneously hypertensive rats.
Topics: Action Potentials; Aging; Animals; Arrhythmias, Cardiac; Hypertension; In Vitro Techniques; Isoprote | 1994 |
Influence of exercise training on myocardial beta-adrenergic signal transduction: differential regulation with age.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Female; GTP-Binding Proteins; Heart | 1994 |
Effects of aging on responses to isoproterenol tilt-table testing in patients with syncope.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Female; Hemodynamics; Humans; Isoprotereno | 1994 |
The effect of age on the beta-adrenergic lipolytic response in healthy humans.
Topics: Adult; Aged; Aging; Blood Glucose; Blood Pressure; Catecholamines; Fatty Acids; Female; Glycerol; He | 1994 |
Effect of age on beta-receptors, Gs alpha- and Gi alpha- proteins in rat heart.
Topics: Adenylyl Cyclases; Aging; Amino Acid Sequence; Animals; Body Weight; GTP-Binding Proteins; Heart Ven | 1994 |
Norepinephrine-induced relaxations in rat aorta mediated by endothelial beta adrenoceptors. Impairment by ageing and hypertension.
Topics: Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isoproter | 1994 |
Relationship between cAMP production and protein secretion in rat submandibular acini: evidence for loss of reserve capacity with age.
Topics: Aging; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Isopro | 1994 |
Age-related changes in beta-adrenergic neuroeffector systems in the human heart.
Topics: Adenylyl Cyclases; Adolescent; Adult; Aging; Binding, Competitive; Child; Child, Preschool; Denervat | 1994 |
Developmental appearance of pineal adrenergic-->guanosine 3',5'-monophosphate response is determined by a process down-stream from elevation of intracellular Ca2+: possible involvement of a diffusible factor.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenal Glands; Aging; Animals; Arachidonic Acid; Calcium; Cell | 1993 |
Alpha-2 adrenergic receptor activity in porcine adipocytes is androgen and age/cell size dependent.
Topics: Adipose Tissue; Aging; Androgens; Animals; Cell Size; Epinephrine; Isoproterenol; Lipolysis; Male; P | 1993 |
Are there any differences in the excitation-contraction coupling of the working myocardium of adult and newborn guinea-pigs?
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Caffeine; Calcium; Electrophysiology; Guinea Pi | 1993 |
Secretion of ions and pharmacological responsiveness in the mouse paw sweat gland.
Topics: Aging; Animals; Colforsin; Culture Techniques; Cyclic AMP; Eccrine Glands; Forelimb; Isoproterenol; | 1994 |
Maturation of catecholamine response and extraneuronal uptake in rabbit trachea.
Topics: Aging; Animals; Animals, Newborn; Catecholamines; In Vitro Techniques; Isoproterenol; Neurons; Norep | 1994 |
Impaired beta-adrenergic receptor-mediated regulation of gene expression in adipocytes from older rats.
Topics: Adenosine Deaminase; Adipocytes; Aging; Animals; Animals, Newborn; Base Sequence; Gene Expression Re | 1994 |
Age-dependent changes in the phosphorylation of nuclear proteins of submandibular glands in isoproterenol-treated rats.
Topics: Aging; Animals; DNA; Isoproterenol; Male; Nuclear Proteins; Phosphorylation; Protein Kinases; Rats; | 1993 |
Adrenoceptor coupling mechanisms which regulate salivary secretion during aging.
Topics: Aging; Animals; Cell Membrane; Cyclic AMP; In Vitro Techniques; Inositol Phosphates; Isoproterenol; | 1993 |
Desipramine desensitizes beta-adrenergic signal transduction in salivary glands: differential regulation with age.
Topics: Adenylyl Cyclases; Aging; Analysis of Variance; Animals; Cerebral Cortex; Desipramine; Down-Regulati | 1993 |
Regulation of capillary exchange capacity in postnatal swine intestine.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Blood Pressure; Capillaries; Hemodynamics; H | 1993 |
Postnatal decrease in muscarinic cholinergic influence on Ca2+ currents of rabbit ventricular cells.
Topics: Adenylate Cyclase Toxin; Aging; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Carbac | 1993 |
Age-related alterations in the phosphorylation of sarcoplasmic reticulum and myofibrillar proteins and diminished contractile response to isoproterenol in intact rat ventricle.
Topics: Aging; Animals; Isoproterenol; Male; Myocardial Contraction; Myofibrils; Phosphorylation; Rats; Rats | 1993 |
The effects of ethanol on gamma-aminobutyric acid-induced depressions of cerebellar Purkinje neurons: influence of beta adrenergic receptor action in young and aged Fischer 344 rats.
Topics: Aging; Animals; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Isoproterenol; Male; Purkinje Cell | 1993 |
Effects of exercise on myocardial adenylate cyclase and Gi alpha expression in senescence.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Aging; Amino Acid Sequence; Animals; Cell Membrane; Cycl | 1993 |
Diminished cardiac contractile response to burn injury in aged guinea pigs.
Topics: Aging; Animals; Burns; Calcium Channels; Depression, Chemical; Diltiazem; Guinea Pigs; Isoproterenol | 1993 |
Motor learning deficits in aged rats are correlated with loss of cerebellar noradrenergic function.
Topics: Aging; Animals; Cerebellum; Drug Synergism; Electrophysiology; gamma-Aminobutyric Acid; Isoprotereno | 1993 |
Cardiac contractile and calcium transport function after burn injury in adult and aged guinea pigs.
Topics: Aging; Animals; Biological Transport; Blood Pressure; Burns; Calcium; Electric Stimulation; Guinea P | 1993 |
Ontogeny of rat myocardial A1 adenosine receptors.
Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Binding, Competitive; Cells, Cultured; C | 1995 |
Adenosine attenuation of isoproterenol-stimulated adenylyl cyclase activity is enhanced with aging in the adult heart.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; | 1996 |
Role of muscarinic M2 receptors in regulating beta-adrenergic responsiveness in maturing rabbit airway smooth muscle.
Topics: Aging; Animals; Diamines; Dose-Response Relationship, Drug; Gallamine Triethiodide; GTP-Binding Prot | 1995 |
A role of asialoglycoproteins for plasma-membrane-induced inhibition of the switching from alpha 1 to beta subtypes in adrenergic response during primary culture of rat hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; As | 1996 |
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Cell Membr | 1996 |
Adenosine and carbachol are not equivalent in their effects on L-type calcium current in rabbit ventricular cells.
Topics: Adenosine; Aging; Amino Acid Sequence; Animals; Animals, Newborn; Calcium Channels; Carbachol; Colfo | 1996 |
Myocardial adenosine A1 and A2 receptor activities during juvenile and adult stages of development.
Topics: Adenosine; Aging; Animals; Coronary Vessels; Drug Synergism; Heart; Isoproterenol; Male; Myocardial | 1996 |
Lymphocyte norepinephrine and epinephrine, but not plasma catecholamines predict lymphocyte cAMP production.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Aged, 80 and over; Aging; Cyclic AMP; Epinephrine; Humans; | 1996 |
Beta-adrenergic modulation of Na-K pump activity in young and adult canine cardiac Purkinje fibers.
Topics: Adrenergic beta-Agonists; Aging; Animals; Dogs; Electrophysiology; Isoproterenol; Models, Biological | 1996 |
Occurrence and properties of the hyperpolarization-activated current If in ventricular myocytes from normotensive and hypertensive rats during aging.
Topics: Aging; Animals; Cardiomegaly; Electric Conductivity; Electrophysiology; Hypertension; Isoproterenol; | 1996 |
Atypical regulation of hepatic adenylyl cyclase and adrenergic receptors during a critical developmental period: agonists evoke supersensitivity accompanied by failure of receptor down-regulation.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Down-Regulation; Female; Heart; Isoprot | 1996 |
Beta-adrenoceptor function changes with age of subject in myocytes from non-failing human ventricle.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Calcium; Cell Size; Cells, Cultured; Child; Coronary D | 1996 |
Age-related differences in beta-adrenergic regulation of repolarization in canine epicardial myocytes.
Topics: Action Potentials; Adrenergic beta-Agonists; Aging; Animals; Calcium; Dogs; Electric Conductivity; I | 1996 |
cAMP signaling mechanisms with aging in rats.
Topics: Aging; Animals; Aorta; Blotting, Western; Catalysis; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase | 1996 |
The effects of aging on cerebellar beta-adrenergic receptor activation and motor learning in female F344 rats.
Topics: Action Potentials; Adrenergic beta-Agonists; Aging; Animals; Cerebellum; Female; gamma-Aminobutyric | 1996 |
Exercise training improves lusitropy by isoproterenol in papillary muscles from aged rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Calcium; Heart; In Vitro Techniques; Isometric Contraction | 1996 |
Ontogeny of beta-adrenergic desensitization in rabbit tracheal smooth muscle.
Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Dinoprostone; Dose-Response Relationship | 1996 |
P48: a novel nuclear protein possibly associated with aging and mortality.
Topics: Aging; Animals; Bone Marrow Cells; Cell Nucleus; Electrophoresis, Gel, Two-Dimensional; Electrophore | 1996 |
Beta-adrenoceptor control of cardiac adenylyl cyclase during development: agonist pretreatment in the neonate uniquely causes heterologous sensitization, not desensitization.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Female; Fluorides; GT | 1995 |
Differences in isoproterenol stimulation of Ca2+ current of rat ventricular myocytes in neonatal compared to adult.
Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Calcium Channel Agonists; Calcium Channe | 1996 |
Properties and modulation of If in newborn versus adult cardiac SA node.
Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Cells, Cultured; Diastole; Heart Rate; Isoprotereno | 1997 |
Thermoregulation with age: role of beta-adrenergic signal transduction.
Topics: Adipose Tissue, Brown; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Body T | 1997 |
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; | 1997 |
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; | 1997 |
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; | 1997 |
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; | 1997 |
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; | 1997 |
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; | 1997 |
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; | 1997 |
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; | 1997 |
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; | 1997 |
Desensitization of alpha 1-, beta- and glucagon receptors in rat hepatocytes: influence of ageing.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Centrifugation, Density Gradien | 1994 |
Effect of donor age on porcine insulin secretion.
Topics: Aging; Animals; Carbachol; Cells, Cultured; Glucose; Insulin; Insulin Secretion; Islets of Langerhan | 1997 |
Expression of adenylyl cyclase mRNAs in the adult, in developing, and in the Brattleboro rat kidney.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Arginine Vasopressin; Calcium; Cell Membrane; C | 1997 |
Impairment of vasodilator function in basilar arteries from aged rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Basilar Artery; Bradykinin; Dose-Response Relationship, Dr | 1997 |
Light-induced changes in frog pineal gland N-acetyltransferase activity.
Topics: Aging; Animals; Arylamine N-Acetyltransferase; Darkness; Eye Enucleation; Isoproterenol; Light; Ligh | 1997 |
Effects of adenosine and isoprenaline in left atria from both neonatal and middle-aged noninsulin-dependent diabetic rat models.
Topics: Adenosine; Aging; Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Diabete | 1997 |
Beta-adrenergic regulation of constitutive nitric oxide synthase in cardiac myocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl | 1997 |
Aging and fluid homeostasis in rats.
Topics: Aging; Angiotensins; Animals; Appetite; Avoidance Learning; Body Fluids; Diuresis; Drinking; Female; | 1997 |
Effect of long-term food restriction on cardiac mechanics.
Topics: Aging; Analysis of Variance; Animals; Body Weight; Calcium; Energy Intake; Heart; In Vitro Technique | 1997 |
Myocardial action potential prolongation by calcium channel activation under calcium free-EGTA conditions in guinea-pigs: developmental and regional variations.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adrenergic b | 1997 |
Differential adrenergic regulation of rat pineal cyclic AMP production and N-acetyltransferase activity during postnatal development: involvement of G alpha s and G alpha i1-2 proteins.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; An | 1997 |
Cardiac muscarinic receptors decrease with age. In vitro and in vivo studies.
Topics: Acetylcholine; Adenylyl Cyclases; Adult; Aged; Aging; Child; Dose-Response Relationship, Drug; Heart | 1998 |
Beta-adrenergic-mediated improvement in left ventricular function by exercise training in older men.
Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Aging; Blood | 1998 |
Myocardial adenosine A1-receptor sensitivity during juvenile and adult stages of maturation.
Topics: Adenosine; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Heart; Heart Rate; Isoproter | 1998 |
Reduced DNA synthesis in primary cultures of hepatocytes from old mice is restored by thymus grafts.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Animals, Newborn; Blood Physi | 1998 |
Effect of aging on beta-adrenergically mediated thermogenesis in men.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Aged; Aging; Basal Metabolism; Body Composition; Bo | 1998 |
Involvement of IsK-associated K+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome.
Topics: Aging; Animals; Blotting, Northern; Cardiotonic Agents; Cells, Cultured; Disease Models, Animal; Ele | 1998 |
Effect of age on in vitro magnesium modulation of vascular reactivity in the rat aorta.
Topics: Acetylcholine; Aging; Animals; Aorta; Calcium Chloride; Dose-Response Relationship, Drug; Endotheliu | 1998 |
Food restriction alters the age-related decline in cardiac beta-adrenergic responsiveness.
Topics: Adrenergic beta-Agonists; Aging; Animals; Food Deprivation; Heart; In Vitro Techniques; Isoprotereno | 1998 |
Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Anti-Inflammatory Agents; Cerebellum; C | 1998 |
Pharmacological and molecular characterisation of beta-adrenoceptors in adult rat diaphragm muscle.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Dose-Respo | 1998 |
Control of arterial tone after long-term coenzyme Q10 supplementation in senescent rats.
Topics: Acetylcholine; Aging; Animals; Coenzymes; Isoproterenol; Male; Mesenteric Arteries; Muscle Contracti | 1998 |
The myocardial beta-adrenergic system in spontaneously hypertensive heart failure (SHHF) rats.
Topics: Aging; Animals; beta-Adrenergic Receptor Kinases; Cyclic AMP-Dependent Protein Kinases; Disease Mode | 1999 |
Influence of chronic ethanol consumption on arterial tone in young and aged rats.
Topics: Acetylcholine; Aging; Alcohol Drinking; Animals; Cromakalim; In Vitro Techniques; Isoproterenol; Mal | 1999 |
Lack of an effect of age on beta-adrenoceptor-mediated lipolysis in isolated human adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; A | 1999 |
Characterisation of the function of adult guinea-pig ventricular myocytes following co-culture with neonatal rat myocytes.
Topics: Aging; Animals; Animals, Newborn; Calcium; Cardiotonic Agents; Cells, Cultured; Coculture Techniques | 1999 |
[The involvement of muscarinic M1 receptor in the regulation of action potentials in mouse isolated right atria].
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Action Potentia | 1998 |
Effects of age on outcome of tilt-table testing.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Child; Female; Heart Rate; Humans | 1999 |
Impaired cholera toxin relaxation with age in rat aorta.
Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Aging; Animals; Aorta, Thoracic; Cholera Toxin; Col | 1999 |
Impaired isoproterenol-induced hyperpolarization in isolated mesenteric arteries of aged rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Age Factors; Aging; Animal | 1999 |
Regulation of myocardial beta-adrenergic receptor function in adult and neonatal rabbits.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; GTP-Binding Proteins; | 1999 |
The influence of animal age on beta-adrenoceptor density and function in tracheal airway smooth muscle.
Topics: Adrenergic beta-Agonists; Aging; Animals; Autoradiography; Catechol O-Methyltransferase; Cricetinae; | 1999 |
Beta-adrenergically stimulated fat oxidation is diminished in middle-aged compared to young subjects.
Topics: Adrenergic beta-Agonists; Adult; Aging; Carbohydrate Metabolism; Dose-Response Relationship, Drug; E | 1999 |
Impaired lusitropy-frequency in the aging mouse: role of Ca(2+)-handling proteins and effects of isoproterenol.
Topics: Adrenergic beta-Agonists; Aging; Animals; Blood Pressure; Calcium-Binding Proteins; Calcium-Transpor | 1999 |
Effects of age and gender on the cardiovascular responses to isoproterenol.
Topics: Adrenergic beta-Agonists; Aging; Cardiovascular System; Humans; Isoproterenol; Receptors, Adrenergic | 1999 |
Left ventricular response to beta-adrenergic stimulation in aging rats.
Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Aging; Analysis of Variance; Animals; Atrial Na | 2000 |
Negative inotropic effects of isoprenaline on isolated left atrial assays from aged transgenic mice with cardiac over-expression of human beta(2)-adrenoceptors.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 2000 |
Functional and morphological modifications of the urinary bladder in aging female rats.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Arecoli | 2000 |
Effects of cyclopentyladenosine on isoproterenol response in adult and senescent cardiac tissue from Fischer 344 rats.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; | 2000 |
Ontogeny of G-protein expression: control by beta-adrenoceptors.
Topics: Adrenergic beta-Agonists; Aging; Animals; Colforsin; Drug Tolerance; Female; Fluorides; Gene Express | 2000 |
Age-related involvement of the endothelium in beta-adrenoceptor-mediated relaxation of rat aorta.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Aorta, Thoracic; Apamin; Aten | 2000 |
Alterations in G-proteins and beta-adrenergic responsive adenylyl cyclase in rat urinary bladder during aging.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; | 2000 |
Adolescent nicotine exposure alters cardiac autonomic responsiveness: beta-adrenergic and m2-muscarinic receptors and their linkage to adenylyl cyclase.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Autonomic Nervous Sys | 2000 |
Angiotensin II enhances beta-adrenergic receptor-mediated vasorelaxation in aortas from young but not old rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Angiotensin II; Animals; Aorta, Thorac | 2000 |
Adaptations in beta-adrenergic cardiovascular responses to training in older women.
Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Aged; Aging; Atropine; Blood Pressure; Cardiova | 2000 |
Age-related differences in messenger ribonucleic acid expression of key proteins involved in adipose cell differentiation and metabolism.
Topics: Abdomen; Adipocytes; Adipose Tissue; Adult; Aging; Bucladesine; Canada; Cell Differentiation; Colfor | 2001 |
Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Calcium-Binding Proteins; Cardiomyop | 2001 |
Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma.
Topics: Adrenergic beta-Agonists; Age Factors; Aging; Animals; Arginine; Blotting, Western; Citrulline; Cycl | 2001 |
No loss in the in vivo efficacy of ischemic preconditioning in middle-aged and old rabbits.
Topics: Aging; Analysis of Variance; Animals; Cardiotonic Agents; Hemodynamics; Ischemic Preconditioning, My | 2001 |
Impaired cardiac contractility response to hemodynamic stress in S100A1-deficient mice.
Topics: Adrenergic beta-Agonists; Aging; Animals; Calcium Signaling; Calcium-Binding Proteins; Gene Targetin | 2002 |
Effects of different inotropic interventions on myocardial function in the developing rabbit heart.
Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Azetidines; Calcium; Calcium-Transportin | 2002 |
Adrenergic-cholinergic interaction that modulates repolarization in the atrium is altered with aging.
Topics: Acetylcholine; Action Potentials; Adrenergic beta-Agonists; Aging; Animals; Dogs; Dose-Response Rela | 2002 |
Biochemical and morphological effects of testosterone treatment on developing sympathetic neurons.
Topics: Aging; Animals; Cell Count; Ganglia, Autonomic; Isoproterenol; Neurons; Rats; Submandibular Gland; T | 1978 |
A comparative study of pineal acetyl-CoA hydrolase and N-acetyltransferase activities.
Topics: Acetyl-CoA Hydrolase; Acetyltransferases; Aging; Animals; Animals, Newborn; Circadian Rhythm; Female | 1979 |
Alpha- and beta-adrenergic mechanisms in the aorta of newborn rabbits and guinea-pigs.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Aorta; Female | 1979 |
Maturation- and species-related differences in inotropic response to isoproterenol.
Topics: Aging; Animals; Animals, Newborn; Guinea Pigs; Isoproterenol; Myocardial Contraction; Rabbits; Speci | 1979 |
Alterations in the cardiovascular system that occur in advanced age.
Topics: Adult; Aged; Aging; Blood Pressure; Cardiomegaly; Cardiovascular Physiological Phenomena; Chemorecep | 1979 |
Effects of 6-hydroxydopamine Treatment at birth on the submaxillary gland of the rat.
Topics: Aging; Animals; Animals, Newborn; Autonomic Fibers, Postganglionic; Choline O-Acetyltransferase; Coc | 1975 |
Biochemical aspects of cardiac muscle differentiation. Possible control of deoxyribonucleic acid synthesis and cell differentiation by adrenergic innervation and cyclic adenosine 3':5'-monophosphate.
Topics: Aging; Animals; Animals, Newborn; Bucladesine; Cell Differentiation; Cyclic AMP; Cyclic GMP; DNA Rep | 1976 |
Vascular adenylate cyclase: role of age and guanine nucleotide activation.
Topics: Adenosine; Adenylyl Cyclases; Aging; Animals; Aorta; Cyclic AMP; Guanine Nucleotides; Guanosine Trip | 1977 |
Age-related parallel decline in beta-adrenergic receptors, adenylate cyclase and phosphodiesterase activity in rat erythrocyte membranes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Aging; Alprenolol; Animals; Benzyl Alcohols; | 1977 |
Regulation of antigen induced changes in cyclic nucleotide levels in NZB/wf1 mice.
Topics: Aging; Animals; Antigens; Antilymphocyte Serum; Complement System Proteins; Cyclic AMP; Dose-Respons | 1978 |
Development of secretory function in rat parotid gland.
Topics: Aging; Amylases; Animals; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Parotid Gland | 1978 |
beta-Adrenergic receptors and catecholamine-sensitive adenylate cyclase in rat fat-cell membranes: influence of growth, cell size and aging.
Topics: Adenylyl Cyclases; Adipose Tissue; Aging; Animals; Binding, Competitive; Isoproterenol; Kinetics; Ma | 1978 |
Vascular relaxation, aging and thyroid hormones.
Topics: Aging; Animals; Aorta; Blood Vessels; Dose-Response Relationship, Drug; Female; Hypophysectomy; Isop | 1978 |
Effect of intra-amnial administration of a cardiotoxic dose of isoproterenol on cyclic AMP levels in the chick embryo heart.
Topics: Aging; Amnion; Animals; Chick Embryo; Cyclic AMP; Heart; Injections; Isoproterenol; Myocardium | 1979 |
Age related changes in hormone binding by target cells and tissues; possible role in altered adaptive responsiveness.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aging; Animals; Aorta; Child; Female; Glucocor | 1975 |
Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the pre-weanling rat.
Topics: Aging; Animals; Atropine; Chlorisondamine; Electrocardiography; Female; Heart Rate; Isoproterenol; M | 1979 |
Age-associated decrease in heart rate response to isoproterenol in dogs.
Topics: Aging; Anesthesia; Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Is | 1979 |
Adrenergic control of glycolysis and pyruvate kinase activity in hepatocytes from young and old rats.
Topics: Aging; Animals; Epinephrine; Glucagon; Glucose; Glycolysis; In Vitro Techniques; Isoproterenol; Lact | 1979 |
Renal circulatory effects of adrenergic stimuli in anesthetized piglets and mature swine.
Topics: Aging; Animals; Electric Stimulation; Isoproterenol; Kidney; Norepinephrine; Regional Blood Flow; Sw | 1979 |
Morphological and functional study of the effect of isoproterenol on salivary gland cells.
Topics: Aging; Animals; Cytoplasmic Granules; Isoproterenol; Protein Biosynthesis; Rats; Submandibular Gland | 1979 |
Postnatal development of adrenergic and cholinergic sensitivity in the isolated rat atria.
Topics: Acetylcholine; Aging; Animals; Carbachol; Heart; Heart Atria; Isoproterenol; Male; Norepinephrine; P | 1977 |
Isoprenaline relaxation in vascular smooth muscle of aged rats. Effect of flunarizine.
Topics: Aging; Animals; Blood Vessels; Drug Interactions; In Vitro Techniques; Isoproterenol; Muscle Contrac | 1977 |
Advanced age as a factor in the response of rodents to drugs [proceedings].
Topics: Aging; Animals; Cricetinae; Female; Hexobarbital; Hydralazine; Isoproterenol; Male; Mesocricetus; Mi | 1978 |
Cardiac output changes during neonatal growth.
Topics: Aging; Animals; Animals, Newborn; Atropine; Cardiac Output; Female; Heart Rate; Isoproterenol; Propr | 1978 |
The postnatal development of adrenoceptor responses to agonists and electrical stimulation in rat isolated atria.
Topics: Aging; Animals; Electric Stimulation; Female; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; | 1978 |
Influence of ageing on the isoprenaline relaxation of aortae from normal and hypertensive rats.
Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; In Vitro Techniques; Isoproterenol; M | 1978 |
Alternative mechanisms for the potentiation of the relaxation evoked by isoprenaline in aortae from young and aged rats.
Topics: Aging; Animals; Aorta, Thoracic; Blood Vessels; Cinnarizine; Drug Synergism; Isoproterenol; Muscle C | 1979 |
The relationship between age and relaxation of vascular smooth muscle in the rabbit and rat.
Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; Isoproterenol; Male; Musc | 1976 |
Sensitivity of the developing chick myocardium to the positive inotropic effects of calcium and isoproterenol.
Topics: Aging; Animals; Animals, Newborn; Calcium; Chick Embryo; Chickens; Heart; In Vitro Techniques; Isopr | 1977 |
Age-related changes in course of restitution of secretory material in rat submandibular gland stimulated with isoproterenol.
Topics: Aging; Animals; Histocytochemistry; Isoproterenol; Leucine; Male; Rats; Submandibular Gland | 1977 |
Concentration of sialic acids in submandibular glands of young and old rats treated with isoproterenol.
Topics: Aging; Animals; Isoproterenol; Male; Rats; Sialic Acids; Submandibular Gland; Time Factors | 1976 |
Effect of aging on regeneration of glandular secretion in rat salivaries.
Topics: Aging; Animals; Isoproterenol; Male; Rats; Regeneration; Salivary Glands; Secretory Rate | 1976 |
Diminished inotropic response of aged myocardium to catecholamines.
Topics: Aging; Animals; Calcium; Heart; Heart Rate; Isoproterenol; Male; Norepinephrine; Rats | 1975 |
[Dependence on age of the effects of catecholamines in man I. Effect of noradrenaline, adrenaline and isoprenaline on blood pressure and heart rate].
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Blood Pressure; Child, Preschool; Epinephrine; Female; | 1975 |
Studies of aqueous humor dynamics in man. V. Effects of acetazolamide and isoproterenol in young and old normal volunteers.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aging; Aqueous Humor; Fem | 1976 |
Drop in the "atypical" beta-adrenergic response and modification of the beta/alpha 2-adrenoceptor balance in fat cells from aging rabbits.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Aging; Animals; Brimonidine Tartrate; Epinephrine; Etha | 1992 |
Influence of animal age on the beta-adrenergic system in cultured rat aortic and mesenteric artery smooth muscle cells.
Topics: Aging; Alprostadil; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response | 1992 |
The effect of donor age on human fibroblast beta-adrenergic receptor response and agonist-induced desensitization.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cyclic AMP; Drug Resistance; Fibroblasts; Humans; In Vitro Te | 1992 |
Beta-adrenergic responsiveness in cultured aorta smooth muscle cells. Effects of subculture and aging.
Topics: Adenylyl Cyclases; Aging; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme A | 1992 |
Age and beta-adrenergic receptor sensitivity to S(-)- and R,S(+/-)-propranolol in humans.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Blood Pressure; Heart Rate; Humans; Isoprotereno | 1992 |
Age-related alterations of isoproterenol-stimulated adenylyl-cyclase activity are partially corrected by thymic graft.
Topics: Adenylyl Cyclases; Aging; Animals; Enzyme Activation; Isoproterenol; Mice; Mice, Inbred BALB C; Mice | 1992 |
The effect of in vitro aging on human lung fibroblast beta-adrenergic receptor density, coupling and response.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Cell Line; Cellular Senescence; Fibroblasts; Guanosine Tripho | 1992 |
Isolated ventricular myocytes from failing and non-failing human heart; the relation of age and clinical status of patients to isoproterenol response.
Topics: Adolescent; Adult; Aged; Aging; Calcium; Cardiotonic Agents; Child; Female; Heart; Heart Failure; Hu | 1992 |
Relationship between potency of L-isoprenaline and beta-adrenoceptor density estimated in single cells from tracheal smooth muscles of guinea pigs of different ages.
Topics: Aging; Animals; Binding, Competitive; Dihydroalprenolol; Guinea Pigs; In Vitro Techniques; Isoproter | 1992 |
Influence of exercise and age on myocardial beta-adrenergic receptor properties.
Topics: Aging; Analysis of Variance; Animals; Binding, Competitive; Female; Heart Rate; Iodocyanopindolol; I | 1992 |
Vascular beta-adrenoceptor-mediated responses in hypertension and ageing in rats.
Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; Isoproterenol; Male; Muscle Contracti | 1992 |
Reduced contractile responses to forskolin and a cyclic AMP analogue in myocytes from failing human ventricle.
Topics: Adult; Aging; Bucladesine; Calcium; Colforsin; Diuretics; Female; Heart Failure; Heart Ventricles; H | 1992 |
Beta-adrenergic receptors and salivary gland secretion during aging.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Female; Iodocyanopindolol; Isoproterenol; Pilocarp | 1992 |
Somatostatin and growth hormone-releasing factor release from Zucker rat hypothalamic tissue.
Topics: Aging; Animals; Growth Hormone-Releasing Hormone; Hypothalamus, Middle; In Vitro Techniques; Iodine | 1992 |
A biochemical analysis of parotid and submandibular salivary gland function with age after simultaneous stimulation with pilocarpine and isoproterenol in female NIA Fischer 344 rats.
Topics: Aging; alpha-Amylases; Animals; DNA; Epidermal Growth Factor; Female; Isoproterenol; Parotid Gland; | 1992 |
Amylase mRNA synthesis and ageing in rat parotid glands following isoproterenol-stimulated secretion.
Topics: Aging; Amylases; Animals; Antisense Elements (Genetics); Blotting, Northern; Immunoblotting; Isoprot | 1992 |
Post-train administration of 9-amino-1,2,3,4-tetrahydroacridine enhances passive avoidance retention and decreases beta-adrenoceptor-linked cyclic AMP formation in middle-aged rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Avoidance Learning; Cerebral Cortex; Conditioning, Psyc | 1992 |
Aging: inotropic effects of Bay K-8644 and nifedipine on rat cardiac muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
[Response of the cardiovascular system in elderly patients to intravenous infusion of isoproterenol and adrenaline].
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Blood Pressure; Dose-Response Relationship, Drug; Epine | 1992 |
Bradykinin-induced venodilation is not impaired with aging in humans.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Bradykinin; Dose-Response Relationship, Drug; Fem | 1992 |
The association of E. coli peritonitis with an impaired and delayed fever response in senescent rats.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Aging; Animals; Escherichia coli Infections; Female; Fever | 1992 |
Effects of subacute exposure to noise on the noradrenergic innervation of the cardiovascular system in young and aged rats: a morphofunctional study.
Topics: Aging; Animals; Aorta; Atrial Function; Cardiovascular Physiological Phenomena; Cardiovascular Syste | 1992 |
Differences in cardiovascular responses to isoproterenol in relation to age and exercise training in healthy men.
Topics: Adult; Aged; Aged, 80 and over; Aging; Hemodynamics; Humans; Isoproterenol; Male; Middle Aged; Oxyge | 1992 |
Nuclear estradiol binding in rat adipocytes. Regional variations and regulatory influences of hormones.
Topics: Adipose Tissue; Aging; Animals; Bucladesine; Cell Nucleus; Estradiol; Insulin; Isoproterenol; Kineti | 1991 |
Beta-adrenergic responsiveness in cultured vascular smooth muscle cells and fibroblasts: effect of age.
Topics: Aging; Analysis of Variance; Animals; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; Fibroblasts; Is | 1991 |
Beta-adrenergic regulation of insulin secretion: evidence of tissue heterogeneity of beta-adrenergic responsiveness in the elderly.
Topics: Adult; Aged; Aging; Blood Glucose; Cyclic AMP; Epinephrine; Female; Heart Rate; Humans; Insulin; Ins | 1991 |
Regional differences in adrenoreceptor status of adipose tissue in adults and prepubertal children.
Topics: Adipose Tissue; Adult; Aging; Analysis of Variance; Child; Female; Humans; In Vitro Techniques; Isop | 1991 |
Beta-adrenergic signal transduction in aging parotid and submandibular salivary glands.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; F | 1991 |
Ontogeny of beta-adrenergic receptor-mediated cyclic AMP generating system in primary cultured neurons.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Aging; Animals; Brain; Cell Division; Cells, Cultured; C | 1991 |
Cardiac beta-adrenoceptor sensitivity and Parkinson's disease.
Topics: Aged; Aging; Blood Pressure; Bromocriptine; Dose-Response Relationship, Drug; Female; Heart Rate; Hu | 1991 |
Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP.
Topics: 5'-Nucleotidase; Aging; Animals; Cardiomegaly; Cerebrovascular Disorders; Disease Susceptibility; Do | 1991 |
Multiple adrenergic receptor subtypes controlling cyclic AMP formation: comparison of brain slices and primary neuronal and glial cultures.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Colfo | 1991 |
Beta-adrenergic receptor activity of cerebral microvessels is reduced in aged rats.
Topics: Adenylyl Cyclases; Aging; Alkaline Phosphatase; Animals; Brain; Cerebrovascular Circulation; gamma-G | 1991 |
Differences in the accessibility of the beta-adrenergic receptor in isolated hepatocytes from foetal and adult rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Female; Glucose; Isoproterenol; Live | 1991 |
Subsensitivity to beta-adrenoceptor agonists in pacemakers isolated from senescent rats.
Topics: Adrenergic beta-Agonists; Aging; Animals; Cocaine; Ethanolamines; Heart; Heart Rate; In Vitro Techni | 1991 |
Beta-adrenoceptor responsiveness in intact leukocytes from adults and newborn infants; effect of phosphodiesterase inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Aging; Cyclic AMP; Humans; | 1990 |
Ontogeny of the adenylate cyclase system in the pulmonary vascular smooth muscle of the fetal lamb.
Topics: Adenylyl Cyclases; Aging; Animals; Cell Membrane; Colforsin; Cyclic AMP; Embryonic and Fetal Develop | 1991 |
Decreased beta-adrenoceptor-mediated vasodilation in aorta from aged rats: possible involvement of a stimulatory GTP-binding protein.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Aorta; Clenbuterol; Colforsin; Cycli | 1991 |
Use-dependent decline in rat aorta sensitivity to contraction by potassium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Acute effects of tetrahydroaminoacridine on beta-adrenoceptor-linked cyclic AMP accumulation in brain of young and middle-aged rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Brain; Cerebral Cortex; Cholinesterase Inhibitors; Cycl | 1991 |
Beta adrenergically mediated cardiac chronotropic and vascular smooth muscle responses during propranolol therapy and withdrawal in young and elderly persons.
Topics: Adult; Aged; Aging; Blood Pressure; Female; Heart Rate; Humans; Isoproterenol; Male; Muscle, Smooth, | 1992 |
Effects of physiological aging on cardiac electrophysiology in perfused Fischer 344 rat hearts.
Topics: Aging; Animals; Atrioventricular Node; Bundle of His; Dose-Response Relationship, Drug; Electrophysi | 1992 |
Age-related impairment of signal transduction and its correction with antioxidants.
Topics: Adenylyl Cyclases; Aging; Animals; Brain; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; | 1991 |
Increased mucin levels in submandibular glands of aged male mice after chronic isoproterenol treatment.
Topics: Aging; Analysis of Variance; Animals; Circadian Rhythm; Female; Injections, Intraperitoneal; Isoprot | 1991 |
Agonist-induced Ca2+ mobilization in the rat submandibular gland during aging and subsequent to chronic propranolol treatment.
Topics: Aging; Animals; Calcium; Carbachol; Female; In Vitro Techniques; Intracellular Fluid; Isoproterenol; | 1991 |
Waning cardiovascular responses to adrenergic drugs in conscious ageing rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascul | 1991 |
Ontogeny of responses of rabbit aorta to atrial natriuretic factor and isoproterenol.
Topics: Aging; Animals; Atrial Natriuretic Factor; Drug Interactions; Isoproterenol; Muscle Contraction; Mus | 1991 |
Ontogeny of renal renin release in spontaneously hypertensive rat and Wistar-Kyoto rat.
Topics: Aging; Angiotensin II; Animals; Hypertension; Isoproterenol; Kidney Cortex; Kidney Tubules, Proximal | 1991 |
Left ventricular responses to experimental aortic coarctation in growing puppies.
Topics: Aging; Animals; Aortic Coarctation; Blood Pressure; Collateral Circulation; Dogs; Heart Ventricles; | 1991 |
[Effects of cernitin pollen extract (CN-009) on the isolated bladder smooth muscles and the intravesical pressure].
Topics: Aging; Animals; Atropine; Cats; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Drug | 1991 |
Norepinephrine and isoproterenol increase the phosphorylation of synapsin I and synapsin II in dentate slices of young but not aged Fisher 344 rats.
Topics: Aging; Animals; Cytoskeletal Proteins; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Mi | 1991 |
Isoproterenol activation of prostaglandin production in guinea-pig airway muscle preparations from immature and mature animals.
Topics: Aging; Animals; Bronchi; Dinoprost; Dinoprostone; Enzyme Activation; Guinea Pigs; Histamine; Isoprot | 1991 |
Dose-dependent effect of prenatal dexamethasone treatment on beta-adrenergic receptor coupling to ornithine decarboxylase and cyclic AMP.
Topics: Aging; Analysis of Variance; Animals; Body Weight; Cyclic AMP; Dexamethasone; Dose-Response Relation | 1990 |
Regulation of postnatal beta-adrenergic receptor/adenylate cyclase development by prenatal agonist stimulation and steroids: alterations in rat kidney and lung after exposure to terbutaline or dexamethasone.
Topics: Adenylyl Cyclases; Aging; Analysis of Variance; Animals; Binding Sites; Body Weight; Colforsin; Dexa | 1990 |
Ontogeny of renal beta adrenoceptors in the sheep.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Binding, Competitive; Ethanol | 1990 |
Age-related changes in responses to nerve stimulation and catecholamines in isolated monkey cerebral arteries.
Topics: Aging; Animals; Cerebral Arteries; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol; | 1991 |
Cardiotoxicity of hydralazine and minoxidil in the rat. Influence of age.
Topics: Aging; Animals; Blood Pressure; Heart Diseases; Heart Rate; Hydralazine; Isoproterenol; Minoxidil; M | 1991 |
Age-associated differences in beta adrenergic-stimulated lipolysis in adipocytes from Sprague-Dawley and Fischer 344 rats.
Topics: Adipose Tissue; Aging; Animals; Body Weight; Glycerol; In Vitro Techniques; Isoproterenol; Lipolysis | 1991 |
[Changes of three types in the secretory systems present in the rat submandibular glands during aging].
Topics: Aging; Animals; Clonidine; Isoproterenol; Male; Norepinephrine; Rats; Receptors, Adrenergic; Saliva; | 1990 |
Age-related changes in relaxant response of vascular smooth muscles to atrial natriuretic peptide.
Topics: Acetylcholine; Aging; Animals; Aorta; Atrial Natriuretic Factor; Body Weight; Dose-Response Relation | 1990 |
The beta-adrenergic transduction system in kidneys from young and senescent rats.
Topics: Adenylyl Cyclase Inhibitors; Aging; Animals; Cyclic AMP; Guanylyl Imidodiphosphate; In Vitro Techniq | 1990 |
Age-dependent alterations in beta-adrenergic receptor function in guinea pig ureter.
Topics: Aging; Animals; Cyclic AMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Isoproterenol; M | 1990 |
Developmental changes in beta-adrenergic and cholinergic interactions on calcium-dependent slow action potentials in rat ventricular muscles.
Topics: Acetylcholine; Action Potentials; Aging; Animals; Calcium; Female; Heart; Heart Ventricles; In Vitro | 1990 |
Catecholamine-induced lipolysis in adipose tissue of the elderly.
Topics: Adipose Tissue; Adult; Age Factors; Aged; Aging; Cells, Cultured; Humans; Isoproterenol; Kinetics; L | 1990 |
Age-related deficit in beta receptor stimulation of cAMP binding in blood vessels.
Topics: Aging; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Kinetics | 1990 |
Role of beta-adrenoceptor-adenylate cyclase system in the developmental decrease in sensitivity to isoprenaline in foetal and neonatal rat heart.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Colforsin; Dihydroalprenolol; Enzyme Activation | 1990 |
Effect of aging on the response of guinea pig trachea to isoprenaline.
Topics: Aging; Animals; Corticosterone; Dihydroalprenolol; Guinea Pigs; In Vitro Techniques; Isoproterenol; | 1990 |
Age-related differences in cyclic AMP metabolism and their consequences on relaxation induced by isoproterenol and phosphodiesterase inhibitors in rat isolated aorta.
Topics: Adenylyl Cyclases; Aging; Animals; Aorta, Thoracic; Cyclic AMP; Isoproterenol; Male; Muscle Relaxati | 1990 |
Prenatal nicotine exposure impairs beta-adrenergic function: persistent chronotropic subsensitivity despite recovery from deficits in receptor binding.
Topics: Aging; Animals; Body Weight; Female; Heart; Heart Rate; Isoproterenol; Maternal-Fetal Exchange; Nico | 1990 |
Effects of age and adenosine in the modulation of insulin action on rat adipocyte metabolism.
Topics: Adenosine; Adipose Tissue; Aging; Animals; Dose-Response Relationship, Drug; Insulin; Isoproterenol; | 1990 |
Protein secretion by rat submandibular glands in response to isoproterenol, alpha-methylnoradrenaline and clonidine during aging.
Topics: Aging; Animals; Clonidine; Isoelectric Focusing; Isoproterenol; Male; Nordefrin; Organ Size; Rats; R | 1990 |
Dietary crude protein levels and the effect of isoproterenol on in vitro lipogenesis in the chicken.
Topics: Aging; Animals; Body Weight; Chickens; Dietary Proteins; Fatty Acid Synthases; Isocitrate Dehydrogen | 1990 |
Age-related differences in the depressor responses to sodium nitroprusside and nifedipine in anaesthetized rats.
Topics: Aging; Animals; Blood Pressure; Ferricyanides; Heart Rate; Isoproterenol; Male; Nifedipine; Nitropru | 1990 |
Force and oxygen consumption in the immature rabbit heart.
Topics: Aging; Animals; Animals, Newborn; Heart Rate; Isoproterenol; Myocardial Contraction; Myocardium; Oxy | 1990 |
Changes in lipid composition and isoproterenol- and ethanol-stimulated adenylate cyclase activity in aging Fischer rat bladders.
Topics: Adenylyl Cyclases; Aging; Animals; Ethanol; Glucose; Guanylyl Imidodiphosphate; Isoproterenol; Lipid | 1990 |
Age-related changes in myocardial relaxation and sarcoplasmic reticulum function.
Topics: Aging; Animals; Biological Transport; Blood Pressure; Calcium; Compliance; Diastole; Guinea Pigs; He | 1990 |
Sympathomimetic protein secretion by young and aged lacrimal gland.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Cyclic AMP; Isoenzymes; Isoproterenol; Lacrimal Apparat | 1986 |
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; B | 1986 |
Beta adrenergic control of macromolecule synthesis in neonatal rat heart, kidney and lung: relationship to sympathetic neuronal development.
Topics: Aging; Animals; DNA; DNA Replication; Heart; Heart Conduction System; Isoproterenol; Kidney; Lung; N | 1987 |
Subsensitivity of the failing human heart to isoprenaline and milrinone is related to beta-adrenoceptor downregulation.
Topics: Aging; Cardiotonic Agents; Coronary Disease; Electric Stimulation; Heart Failure; Humans; In Vitro T | 1988 |
Developmental increase in the inotropic and cyclic AMP response to isoproterenol in embryonic and newly hatched chicks.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Animals, Newborn; Chick Embryo; Chickens; Cyclic AMP; I | 1989 |
Ontogeny of isoproterenol-stimulated renin secretion from sheep renal cortical slices.
Topics: Aging; Animals; Animals, Newborn; Aspirin; Edetic Acid; Fetus; Gestational Age; Isoproterenol; Kidne | 1989 |
Dissociation between c-fos gene expression and DNA synthesis in rat parotid glands.
Topics: Aging; Animals; Blotting, Northern; Carbachol; DNA; Epinephrine; Gene Expression; Isoproterenol; Mal | 1989 |
Comparison of age-related changes in prostaglandin E1 and beta-adrenergic responsiveness of vascular smooth muscle in adult males.
Topics: Adult; Aging; Alprostadil; Dose-Response Relationship, Drug; Hand; Humans; Infusions, Intravenous; I | 1989 |
Physiological response to isoproterenol and coupling of beta-adrenergic receptors in young and elderly human subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Epinephrine; Heart Rate; Humans; Isoproterenol; Middle Aged; | 1989 |
Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age.
Topics: Aging; Animals; Aorta; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mesenteric A | 1989 |
[Lack of negative regulation of beta-adrenoreceptor affinity by guanine nucleotides in embryonic membranes and its induction by the GTP-binding protein from mature protein].
Topics: Aging; Animals; Chick Embryo; Chickens; GTP-Binding Proteins; Guanine Nucleotides; Intracellular Mem | 1989 |
Effect of age on acute regulation of beta-adrenergic responses in mononuclear leukocytes.
Topics: Adult; Aged; Aging; Alprostadil; Blood Pressure; Catecholamines; Cyclic AMP; Heart Rate; Humans; Iso | 1989 |
A functional study of the development of the cardiac sympathetic neuroeffector junction in the SHR.
Topics: Aging; Animals; Blood Pressure; Clonidine; Desipramine; Dose-Response Relationship, Drug; Electric S | 1989 |
Lymphocyte beta-adrenoceptor/effector complex in aging and dementia of the Alzheimer type.
Topics: Adult; Aged; Aging; Alzheimer Disease; Cyclic AMP; Humans; Isoproterenol; Lymphocytes; Receptors, Ad | 1989 |
Age-related alteration in the catecholamine-sensitive adenylate cyclase system of the rat cerebral cortex.
Topics: Adenylyl Cyclases; Aging; Animals; Catecholamines; Cell Membrane; Cerebral Cortex; Enzyme Activation | 1989 |
Effects of age on urinary bladder function in the male rat.
Topics: Aging; Animals; Bethanechol; Bethanechol Compounds; Isoproterenol; Male; Muscle Contraction; Muscle, | 1989 |
Altered beta-adrenoceptor internalization does not explain reduced beta-adrenergic responsiveness in the elderly.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Animals; Epinephrine; H | 1989 |
Intracellular distribution of cardiac beta-adrenoceptors in SHR and WKY.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Heart; Hypertension; In Vitro Techni | 1989 |
Lipolytic response of bovine adipose tissue to alpha and beta adrenergic agents 30 days pre- and 120 days postpartum.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; A | 1989 |
Myocardial response to alpha-agonist (phenylephrine) in relation to age.
Topics: Adult; Aging; Animals; Depression, Chemical; Heart; Heart Atria; Heart Ventricles; Humans; In Vitro | 1989 |
The response to isoproterenol-stimulated adenylate cyclase activity after administration of L-triiodothyronine is reduced in aged rats.
Topics: Adenylyl Cyclases; Aging; Animals; Drug Interactions; Guanosine Triphosphate; Heart; Isoproterenol; | 1989 |
Effects of isoproterenol treatment on the parathyroid glands in golden hamsters of different ages, with special reference to the frequency of lipid droplets.
Topics: Aging; Animals; Calcium; Cricetinae; Female; Isoproterenol; Lipids; Male; Mesocricetus; Microscopy, | 1989 |
Cardiovascular regulatory functions in elderly patients with hypertension.
Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Blood Pressure; Cardiovascular System; Female; Heart; H | 1989 |
Vasodilator responses to dopamine in rat perfused mesentery are age-dependent.
Topics: Aging; Animals; Dopamine; Drug Interactions; In Vitro Techniques; Isoproterenol; Male; Nitroprusside | 1989 |
The effects of ageing on neuronal uptake of noradrenaline in the rat.
Topics: Aging; Animals; Cocaine; Corticosterone; Decerebrate State; Heart; Heart Rate; Hemodynamics; Isoprot | 1989 |
Age-associated alterations in hepatic beta-adrenergic receptor/adenylate cyclase complex.
Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Cell Separation; Enzyme Activation; Glycoge | 1987 |
Emergence of beta adrenergic-responsive hepatic glycogenolysis in male rats during post-maturational aging.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Epinephrine; Glucagon; Glucose; Gly | 1987 |
Stimulation and inhibition of lipolysis in isolated rat adipocytes: evidence for age-related changes in responses to forskolin and PGE1.
Topics: Adipose Tissue; Aging; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Lipolysis | 1987 |
Age-related and testicular regression-induced changes in adenosine 3',5'-monophosphate responses in cultured hamster Sertoli cells.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Aging; Animals; Cells, Cultured; Cholera Toxin; Col | 1988 |
Iontophoretic study of adrenergic and cholinergic skin vessel reactivity in normal ageing and Alzheimer's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Autonomic Agents; Humans; Iont | 1987 |
Age-associated decrease in beta-adrenergic receptors and adenylate cyclase activity in rat brown adipose tissue.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Aging; Animals; Body Temperature Regulation; Colforsin; El | 1988 |
Effects of chronic isoproterenol administration on beta 1-adrenoceptors and growth of pancreas of young and adult rats.
Topics: Aging; Animals; Atenolol; Butoxamine; Cell Differentiation; Cell Membrane; Dihydroalprenolol; DNA; I | 1988 |
Glandular adenylate cyclase system in genetic hypertension: age-dependent response to catecholamines.
Topics: Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Fluorides; Hyperten | 1988 |
[Tetracycline and energy metabolism of cardiac mitochondria in old rabbits after isoproterenol premedication].
Topics: Adenine Nucleotides; Adenosine Triphosphatases; Aging; Animals; Electron Transport Complex IV; Energ | 1988 |
Noradrenergic modulation of olfactory bulb excitability in the postnatal rat.
Topics: Action Potentials; Aging; Animals; Electric Stimulation; Female; Isoproterenol; Male; Norepinephrine | 1988 |
Age does not alter human vascular and nonvascular beta 2-adrenergic responses to isoproterenol.
Topics: Adult; Aged; Aging; Blood Glucose; Humans; Infusions, Intravenous; Insulin; Isoproterenol; Male; Mid | 1988 |
Increased beta-adrenergic receptors in the light-density membrane fraction in lungs from senescent rats.
Topics: Aging; Animals; Centrifugation; Female; Isoproterenol; Lung; Membranes; Myocardium; Rats; Rats, Inbr | 1988 |
Ontogeny of alpha- and beta-adrenergic anorexia in rats.
Topics: Aging; Animals; Anorexia; Appetite; Appetite Depressants; Feeding and Eating Disorders; Female; Isop | 1988 |
Properties of cardiac alpha- and beta-adrenoceptors in spontaneously hypertensive rats.
Topics: Aging; Animals; Cardiomegaly; Electric Stimulation; Hypertension; In Vitro Techniques; Isoproterenol | 1988 |
Isoproterenol-sensitive adenylate cyclase in glomeruli isolated from young and adult rat renal cortex.
Topics: Adenylyl Cyclases; Aging; Alkaline Phosphatase; Animals; Enzyme Activation; Fluorides; gamma-Glutamy | 1985 |
Cyclic AMP in normal and sympathetically aneural chick hearts during development.
Topics: Adrenergic beta-Antagonists; Aging; Animals; Chick Embryo; Cyclic AMP; Embryonic and Fetal Developme | 1986 |
Accumulation of adenosine 3',5'-monophosphate in slices of rat cerebral cortex induced by alpha-adrenergic agonists. I. Responses to methoxamine and norepinephrine in adult and neonatal tissue.
Topics: Adenosine; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Cerebral Cortex; Cyclic A | 1987 |
Postnatal development of beta-adrenergic response in ventricular muscle of the rat heart.
Topics: Adrenergic beta-Agonists; Aging; Animals; Female; Heart; In Vitro Techniques; Isoproterenol; Male; R | 1988 |
Comparison between the effects of aging on antagonist and agonist interactions with beta-adrenergic receptors on human mononuclear and polymorphonuclear leukocyte membranes.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aging; Drug Interactions; Female | 1988 |
Effects of neonatal treatment with 6-aminonicotinamide on basal and isoproterenol-stimulated ornithine decarboxylase activity in cerebellum of the development rat.
Topics: 6-Aminonicotinamide; Aging; Animals; Animals, Newborn; Body Weight; Cerebellum; Enzyme Activation; I | 1985 |
cAMP metabolism and lipolysis in brown adipocytes of hamsters consuming a cafeteria diet.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Aging; Animals; Body Temperature Regulation; Colforsin; Cr | 1985 |
Influences of age on the positive inotropic effect mediated by alpha- and beta-adrenoceptors in rat ventricular strips.
Topics: Aging; Animals; Atenolol; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Phenylep | 1985 |
Hepatic adenylate cyclase. Development-dependent coupling to the beta-adrenergic receptor in the neonate.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Cell Membrane; Cholera Toxin; Dihydroalprenolol | 1985 |
Effect of aging on the response of the cerebral cortex to noradrenergic denervation.
Topics: Adenylyl Cyclases; Aging; Animals; Cerebral Cortex; Cyclic AMP; Dominance, Cerebral; Hydroxydopamine | 1985 |
Age-related reduction of beta-adrenoceptor sensitivity in rat heart occurs by multiple mechanisms.
Topics: Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Dihydroalprenolol; Heart; Isoproterenol; Kinetics; Ma | 1985 |
Decreased beta-adrenergic responsiveness during senescence.
Topics: Adenylyl Cyclases; Aging; Animals; Blood Platelets; Heart; Humans; In Vitro Techniques; Isoprotereno | 1986 |
Effect of age on beta adrenergic relaxation of the rat jugular vein.
Topics: Age Factors; Aging; Animals; In Vitro Techniques; Isoproterenol; Jugular Veins; Male; Rats; Rats, In | 1986 |
Lymphocyte protein kinase activity in cells from young and elderly men and women.
Topics: Adult; Aged; Aging; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Humans; Isoprotere | 1985 |
Sarcolemmal Na+-Ca2+ exchange during the development of genetically determined cardiomyopathy.
Topics: Aging; Animals; Biological Transport; Calcium; Cardiomyopathies; Cricetinae; Isoproterenol; Mesocric | 1985 |
Developmental alteration in adrenergic regulation of hepatic glycogen phosphorylase.
Topics: Aging; Animals; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Liver; Liver Glycogen; | 1986 |
Autonomic interactions in the aging heart: age-associated decrease in muscarinic cholinergic receptor mediated inhibition of beta-adrenergic activation of adenylate cyclase.
Topics: Adenylyl Cyclases; Aging; Animals; Atropine; Carbachol; Cell Membrane; Enzyme Activation; Guanosine | 1986 |
Beta-adrenergic receptors in the elderly are not less sensitive to timolol.
Topics: Adult; Aged; Aging; Blood Pressure; Female; Heart Rate; Humans; Injections, Intravenous; Isoproteren | 1986 |
Effect of age on the formation of cyclic nucleotides in guinea-pig tracheal smooth muscle in response to pharmacological agents.
Topics: Aging; Alprostadil; Animals; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pig | 1986 |
Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man.
Topics: Adult; Aged; Aging; Cyclic AMP; Humans; Isoproterenol; Male; Middle Aged; Muscle Relaxation; Muscle, | 1986 |
Regulation of beta adrenergic receptors on rat mononuclear leukocytes by stress: receptor redistribution and down-regulation are altered with aging.
Topics: Aging; Animals; Cyclic AMP; Dihydroalprenolol; Isoproterenol; Male; Monocytes; Propanolamines; Propr | 1987 |
[Age dependent quantitative evaluations of sensitivity changes in beta adrenergic receptors to isoprenaline and propranolol].
Topics: Adult; Aged; Aging; Humans; Isoproterenol; Male; Middle Aged; Propranolol; Receptors, Adrenergic, be | 1986 |
Effects of thyroid hormone on beta-adrenergic responsiveness of aging cardiovascular systems.
Topics: Aging; Animals; Body Weight; Cardiovascular Physiological Phenomena; Catecholamines; Decerebrate Sta | 1987 |
Beta-adrenergic receptors, glucagon receptors, and their relationship to adenylate cyclase in rat liver during aging.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Glucagon; Guanine Nucleotides; Guan | 1987 |
Role of alpha-adrenoceptors for adipocyte size in man.
Topics: Adipose Tissue; Adolescent; Adult; Aging; Child; Child, Preschool; Cross-Sectional Studies; Female; | 1987 |
Decrease in force potentiation and appearance of alpha-adrenergic mediated contracture in aging rat skeletal muscle.
Topics: Aging; Animals; Catecholamines; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Musc | 1987 |
Diet restriction retards the age-related loss of beta-adrenergic receptors and adenylate cyclase activity in rat lung.
Topics: Adenylyl Cyclases; Aging; Animal Nutritional Physiological Phenomena; Animals; Colforsin; Diet; Epin | 1987 |
Increased incidence of isoproterenol-induced ventricular fibrillation in aging rats.
Topics: Aging; Animals; Blood Pressure; Electrocardiography; Heart Rate; Isoproterenol; Male; Rats; Receptor | 1987 |
Differential regulation of testicular transferrin and androgen-binding protein secretion in primary cultures of rat Sertoli cells.
Topics: Aging; Androgen-Binding Protein; Animals; Blood; Cell Count; Cells, Cultured; Deferoxamine; Epiderma | 1986 |
Melanocyte-stimulating hormone and the regulation of tyrosinase activity in hair follicular melanocytes of the mouse.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aging; Animals; Catechol Oxidase; Female; Hair; Hair Color; | 1986 |
Regulation of lipolysis during the neonatal period. Importance of thyrotropin.
Topics: Adenosine Deaminase; Adipose Tissue; Adult; Aging; Child; Child, Preschool; Epinephrine; Gestational | 1988 |
Effects of arterial hypoxia and isoproterenol on in vitro postnatal intestinal circulation.
Topics: Aging; Animals; Animals, Newborn; Hypoxia; Intestines; Isoproterenol; Jejunum; Oxygen Consumption; R | 1988 |
Heart lactate dehydrogenase isoenzymes as a function of age, exercise and experimental necrosis.
Topics: Aging; Animals; Isoenzymes; Isoproterenol; L-Lactate Dehydrogenase; Myocardium; Necrosis; Physical C | 1988 |
[Age-related characteristics of a change in cardiac systolic and diastolic functions under the influence of the adrenergic stimulants isadrin and mezaton (based on data from a computer analysis of the echocardiogram)].
Topics: Adult; Aged; Aged, 80 and over; Aging; Computers; Diastole; Echocardiography; Humans; Isoproterenol; | 1988 |
Metabolic hyperemia is reduced in adult vs. immature guinea pig hearts.
Topics: Adenosine; Aging; Animals; Coronary Circulation; Guinea Pigs; Heart; In Vitro Techniques; Isoprotere | 1988 |
Milrinone effects in the isolated immature rabbit heart.
Topics: Aging; Animals; Blood Pressure; Cardiotonic Agents; Heart; Heart Rate; In Vitro Techniques; Isoprote | 1988 |
Comparative electrophysiological response of young and old rat myocardium to pharmacological agents.
Topics: Action Potentials; Aging; Amiloride; Animals; Electric Stimulation; Female; Heart; Isoproterenol; Ni | 1988 |
[Aging and cardiac function].
Topics: Adult; Aged; Aged, 80 and over; Aging; Echocardiography; Female; Heart; Heart Function Tests; Hemody | 1988 |
Cloning and sequencing of cDNA encoding a rat salivary cysteine proteinase inhibitor inducible by beta-adrenergic agonists.
Topics: Aging; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cloning, Molecular; Cysteine | 1988 |
Aging and aortic impedance in beagle dogs.
Topics: Aging; Animals; Aorta; Dogs; Female; Hemodynamics; Isoproterenol; Nitroprusside; Phenylephrine; Vasc | 1988 |
Inotropic responses change during postnatal maturation in rabbit.
Topics: Aging; Animals; Animals, Newborn; Cardiotonic Agents; Colforsin; Female; Heart; Imidazoles; Isoprote | 1988 |
Aging and rat pacemaker sensitivity to beta-adrenoceptor agonists.
Topics: Action Potentials; Aging; Animals; Heart Atria; Heart Rate; Isoproterenol; Male; Myocardial Contract | 1987 |
Age-dependent changes in the response of isolated beagle coronary arteries to transmural electrical stimulation and catecholamines.
Topics: Acetylcholine; Aging; Animals; Catecholamines; Coronary Circulation; Coronary Vessels; Dinoprost; Do | 1986 |
Responsiveness to vasoconstrictor and dilator agents of senescent beagle cerebral arteries.
Topics: Adenosine; Aging; Animals; Basilar Artery; Cerebral Arteries; Dogs; Epoprostenol; Female; Histamine; | 1986 |
Alterations with age of the response to vasodilator agents in isolated mesenteric arteries of the beagle.
Topics: Acetylcholine; Adenosine; Aging; Animals; Dogs; Endothelium; Epoprostenol; Female; Histamine; In Vit | 1986 |
Altered endothelial modulation of vascular tone in aging and hypertension.
Topics: Adenosine; Aging; Animals; Blood Vessels; Desoxycorticosterone; Dose-Response Relationship, Drug; En | 1987 |
Temperature-dependence of maturation of chronotropic and inotropic responses to isoproterenol.
Topics: Aging; Animals; Animals, Newborn; Electric Stimulation; Female; Heart Rate; Isoproterenol; Male; Myo | 1987 |
Development and properties of the secretory response in rat sweat glands: relationship to the induction of cholinergic function in sweat gland innervation.
Topics: Aging; Animals; Atropine; Electric Stimulation; Isoproterenol; Norepinephrine; Rats; Sciatic Nerve; | 1987 |
[Regulation of isoproterenol-induced salivary gland hyperplasia in young and old mice by substances affecting the serotonin- and dopaminergic systems].
Topics: Aging; Animals; Female; Freund's Adjuvant; Hyperplasia; Isoproterenol; Levodopa; Mice; Mice, Inbred | 1986 |
Ornithine decarboxylase activity in the neonatal rat heart following prenatal exposure to ethylene glycol monomethyl ether.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Ethylene Glycols; Female; Isoproterenol; Male; Myocar | 1986 |
Alterations of rat cardiac adenylate cyclase activity with age.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Glucagon; Guanylyl Imidodiphosphate; Isoproterenol; Ma | 1986 |
Age dependence of adenylate cyclase in guinea pig ureter homogenate.
Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Colforsin; Enzyme Activation; Ethanol; Guanosine Tri | 1986 |
Effect of age on blood pressure and small vessel reactivity in male rabbits.
Topics: Aging; Animals; Blood Pressure; Female; Heart Rate; Histamine; Isoproterenol; Male; Muscle, Smooth, | 1986 |
Effects of dystrophy and age on hamster tracheal smooth muscle function.
Topics: Aging; Airway Resistance; Animals; Carbachol; Cricetinae; Histamine; In Vitro Techniques; Isoprotere | 1986 |
Developmental changes in the effects of beta-adrenergic blocking concentrations of propranolol on canine Purkinje fibers.
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Dogs; Heart Conduction System; Isoproterenol; P | 1986 |
Chronotropic and inotropic effects on atria of chronic ethanol ingestion in the aging rat.
Topics: Aging; Animals; Arrhythmias, Cardiac; Depression, Chemical; Ethanol; Heart Atria; Heart Rate; Isopro | 1987 |
Developmental considerations in neonatal failure.
Topics: Aging; Animals; Blood Circulation; Body Temperature Regulation; Cardiac Output; Digitalis; Digoxin; | 1985 |
Neonatal steroid treatment reduces catecholamine-induced increases in pineal serotonin N-acetyltransferase activity.
Topics: Acetyltransferases; Aging; Animals; Animals, Newborn; Arylamine N-Acetyltransferase; Catecholamines; | 1985 |
Drinking by senescent and adult rats in response to regulatory challenges.
Topics: Aging; Animals; Drinking; Eating; Female; Isoproterenol; Male; Rats; Rats, Inbred Strains; Saline So | 1985 |
Electrophysiological analysis of the nature of adrenoceptors in the rat basilar artery during development.
Topics: Action Potentials; Aging; Animals; Basilar Artery; Female; Iontophoresis; Isoproterenol; Male; Membr | 1985 |
Regulation of the adenosine cyclic 3',5'-monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine.
Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic alp | 1973 |
Changes in the carotid pulse which occur with age and hypertension.
Topics: Adult; Aging; Amyl Nitrite; Angiotensin II; Arteriosclerosis; Blood Pressure; Carotid Arteries; Elec | 1966 |
Adenylate cyclase activity in rat submandibular gland during postnatal development.
Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Body Weight; Carbon Radioisotopes; Cyclic AMP; | 1974 |
Increased sensitivity of sinoatrial pace-maker to acetylcholine and to catecholamines at the onset of autonomic neuroeffector transmission in chick embryo heart.
Topics: Acetylcholine; Aging; Animals; Atropine; Autonomic Fibers, Postganglionic; Chick Embryo; Electric St | 1974 |
Change of the relative proportion of various forms of phosphoenolpyruvate carboxykinase in chicken liver possibly associated with enhanced gluconeogenesis.
Topics: Aging; Animals; Bicarbonates; Carbon Radioisotopes; Chickens; Chromatography, Ion Exchange; Cold Tem | 1974 |
The effect of prostaglandin E2 on the arterial blood pressure of normotensive and spontaneously hypertensive rats.
Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, | 1974 |
Interrelation of aging, gonadial steroidal hormone activity and lipid metabolism.
Topics: Aging; Animals; Castration; Cholesterol; Female; Gonadal Steroid Hormones; Gonads; Humans; Isoproter | 1974 |
Myocardial loss of functional magnesium. II. In cardiomyopathies of diverse etiology.
Topics: Adult; Age Factors; Aging; Animals; Calcium; Cricetinae; Heart; Heart Diseases; Heart Failure; Human | 1972 |
Possible changes in tissue sensitivity in the age-dependent stimulation of DNA synthesis in vivo.
Topics: Aging; Animals; Body Weight; DNA; Isoproterenol; Male; Rats; Submandibular Gland; Thymidine; Time Fa | 1973 |
The effect of age on -adrenoceptor activity in tracheal smooth muscle.
Topics: Aging; Animals; Guinea Pigs; Isoproterenol; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Adr | 1973 |
Age-dependent regulation of mammalian DNA synthesis and cell division in vivo by glucocorticoids.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Age Factors; Aging; Animals; Cell Division; DNA; Drug Resist | 1974 |
Age-dependent regulation of isoproterenol-stimulated DNA synthesis in rat salivary gland in vivo.
Topics: Age Factors; Aging; Animals; Circadian Rhythm; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; I | 1974 |
Rat atrial alkaline phosphatase activity and its response to isoprenaline (isoproterenol) during postnatal development.
Topics: Aging; Alkaline Phosphatase; Animals; Animals, Newborn; Enzyme Induction; Heart Atria; Histocytochem | 1972 |
The supersensitivity of isolated rabbit atria and aortic strips produced by 6-hydroxydopamine.
Topics: Aging; Animals; Aorta; Barium; Dimethylphenylpiperazinium Iodide; Dopamine; Drug Interactions; Drug | 1972 |
Further studies on the effect of ageing on beta-adrenoceptor activity of rat aorta.
Topics: Aging; Animals; Aorta, Thoracic; Female; In Vitro Techniques; Isoproterenol; Male; Nitrites; Phentol | 1971 |
[Therapy of acute myocardial infarct with particular reference to arrhythmia and myocardial contractibility disorders].
Topics: Adult; Aged; Aging; Arrhythmias, Cardiac; Atropine; Cardiac Glycosides; Cortisone; Electric Counters | 1971 |
Characteristics of reactive hyperemia in old and young dogs.
Topics: Acetylcholine; Aging; Animals; Blood Flow Velocity; Dogs; Epinephrine; Histamine; Hyperemia; Isoprot | 1965 |
[The relaxing response of the coronary vessels to sympathic stimuli diminishes with age].
Topics: Aging; Animals; Cattle; Coronary Vessels; Epinephrine; Horses; In Vitro Techniques; Isoproterenol; T | 1965 |