Page last updated: 2024-10-29

isoproterenol and Aging

isoproterenol has been researched along with Aging in 515 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" Long non-coding RNA myocardial infarction associated transcript (LncMIAT) is closely related to heart disease, and here, we were the first to discover that LncMIAT may act as an miR-144 sponge in isoproterenol-induced cardiac hypertrophy."7.96The Expression of microRNA in Adult Rat Heart with Isoproterenol-Induced Cardiac Hypertrophy. ( Bai, L; Chen, L; Fan, Y; Gan, M; Guo, Z; Hao, X; Jiang, D; Li, X; Shen, L; Tan, Y; Zhang, S; Zhu, L, 2020)
"The diagnosis of neuromediated syncope is often established with isoproterenol head-up tilt-table testing."7.69Effects of aging on responses to isoproterenol tilt-table testing in patients with syncope. ( Sheldon, R, 1994)
"Prolonged beta-adrenergic stimulation obtained by subcutaneous injection of isoproterenol in unanesthetized, unrestrained rats elicited ventricular fibrillation in approximately 80% of animals at 10-12 months of age."7.67Increased incidence of isoproterenol-induced ventricular fibrillation in aging rats. ( Anversa, P; Guideri, G; Hiler, B; Olivetti, G; Ricci, R, 1987)
" A histological analysis revealed that chronic intake of MEL diminished the age-dependent changes in the structure of muscle fibers of the left ventricle, muscle fiber swelling, and injury zones characteristic of acute cardiac failure caused by ISO."5.48Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. ( Akatov, V; Baburina, Y; Fadeeva, I; Krestinina, O; Kruglov, A; Odinokova, I; Sotnikova, L; Zvyagina, A, 2018)
" Dose-response curves for bradykinin were constructed using the dorsal hand vein compliance technique in veins preconstricted with phenylephrine in 27 volunteers (16 male, 11 female) aged 18 to 81 years."5.28Bradykinin-induced venodilation is not impaired with aging in humans. ( Blaschke, TF; Dachman, WD; Ford, GA; Hoffman, BB, 1992)
"These results show that, in humans, hypertension does not lead to a decrease in chronotropic responses to infusion of the beta-agonist isoproterenol and causes only a modest decrease in left ventricular responses."5.08Age, hypertension, and cardiac responses to beta-agonist in humans. ( Fourney, A; Leenen, FH; White, M, 1998)
" Long non-coding RNA myocardial infarction associated transcript (LncMIAT) is closely related to heart disease, and here, we were the first to discover that LncMIAT may act as an miR-144 sponge in isoproterenol-induced cardiac hypertrophy."3.96The Expression of microRNA in Adult Rat Heart with Isoproterenol-Induced Cardiac Hypertrophy. ( Bai, L; Chen, L; Fan, Y; Gan, M; Guo, Z; Hao, X; Jiang, D; Li, X; Shen, L; Tan, Y; Zhang, S; Zhu, L, 2020)
" However, Mstn-/- mice responded better to isoproterenol stress tests with greater increases in fractional shortening and ejection fraction-differences that were again more apparent in females and which are consistent with physiological cardiac hypertrophy."3.78The aging myostatin null phenotype: reduced adiposity, cardiac hypertrophy, enhanced cardiac stress response, and sexual dimorphism. ( Garikipati, DK; Jackson, MF; Luong, D; Nelson, OL; Rodgers, BD; Stanton, JB; Vang, DD, 2012)
"Isolated perfused hearts from young (3-5 months) and aging (24-25 months) rats were subjected to 60 min of 50% coronary flow reduction and 30 min of isoproterenol (Iso) stimulation starting at 30 min of ischemia."3.73Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury. ( Gao, F; Grunwald, Z; Hu, A; Li, D; Liu, H; Ma, XL; Qu, Y; Sharifi-Azad, S; Sun, JZ; Tao, L, 2006)
"To determine if centrally reducing sympathetic tone with clonidine will reverse the downregulation in the alpha-adrenergic (alphaAR) and beta-adrenergic (betaAR) responses seen with normal aging."3.73Normal aging impairs upregulation of the beta-adrenergic but not the alpha-adrenergic response: aging and adrenergic upregulation. ( Levy, WC; Madden, KM; Stratton, JR, 2006)
"The diagnosis of neuromediated syncope is often established with isoproterenol head-up tilt-table testing."3.69Effects of aging on responses to isoproterenol tilt-table testing in patients with syncope. ( Sheldon, R, 1994)
" The effects of aging on the responsiveness of the isolated pacemaker of the rat to the chronotropic effect of norepinephrine, isoproterenol and soterenol were studied."3.68Subsensitivity to beta-adrenoceptor agonists in pacemakers isolated from senescent rats. ( de Moraes, S; Spadari, RC, 1991)
" The effects of isoproterenol (ISP) and chemical sympathectomy (6-hydroxydopamine treatment) on myocardial beta-receptors were also investigated in 10 and 24 week-old SHRS and WKY to examine the effects of hypertension and aging on receptor regulation."3.68Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP. ( Ikawa, H; Suzuki, A, 1991)
"Cardiac aging is characterized by a reduced heart rate response to beta-agonist stimulation with isoproterenol, but whether the ejection fraction and other cardiovascular responses are reduced in humans is largely unknown."3.68Differences in cardiovascular responses to isoproterenol in relation to age and exercise training in healthy men. ( Abrass, IB; Cerqueira, MD; Kahn, SE; Levy, WC; Schwartz, RS; Stratton, JR; Veith, RC, 1992)
"We determined the effects of D-fenfluramine treatment on the changes in vascular reactivity induced by aging."3.68Effect of aging and drug-induced weight reduction on rat vascular reactivity. ( Boulanger, M; Duhault, J; Feletou, M; Moreau, N, 1993)
"Passive head-up tilt testing with or without infusion of isoproterenol is used in the investigation and management of patients with syncope."3.68Head-up tilt testing with and without isoproterenol infusion in healthy subjects of different ages. ( Lurie, K; Newman, D; Rosenqvist, M; Scheinman, MM; Schwartz, J; Washington, C, 1993)
"The ability of the muscarinic receptor agonist, carbachol, to inhibit beta-adrenergic activation of adenylate cyclase was examined in cardiac membranes from 6-month (young adult) and 24-month (aged) old rats in an effort to assess the effect of aging on adrenergic-cholinergic interactions in the heart."3.67Autonomic interactions in the aging heart: age-associated decrease in muscarinic cholinergic receptor mediated inhibition of beta-adrenergic activation of adenylate cyclase. ( Narayanan, N; Tucker, L, 1986)
"To study potential cardiac receptor alterations during the development of spontaneous hypertension, specific binding of [3H]-2-N(2,6-dimethoxyphenoxyethyl)amino-methyl-1,4-benzodioxane, (-)-[3H]dihydroalprenolol and (-)-[3H]quinuclidinyl benzilate in ventricles of Wistar Kyoto rats (WKY), spontaneously hypertensive rats (SHR) and stroke-prone SHR (SHRSP) at different ages was determined."3.67Alterations in cardiac alpha and beta adrenoceptors during the development of spontaneous hypertension. ( Hayashi, E; Hayashi, M; Ishima, T; Okada, T; Tomita, T; Yamada, S, 1984)
"To elucidate the association of beta-adrenergic receptors with decreased myocardial catecholamine responsiveness in aging, we investigated the chronotropic response to isoproterenol and myocardial beta-adrenergic receptors in Fisher 344 rats of 3, 12, and 24 months of age."3.66Isoproterenol responsiveness and myocardial beta-adrenergic receptors in young and old rats. ( Abrass, IB; Davis, JL; Scarpace, PJ, 1982)
"Isoproterenol alone was infused in 14 young subjects (age, 30 +/- 2 years) and 15 older healthy volunteers (age, 60 +/- 2 years) and together with ganglionic blockade (trimethaphan) in eight young and eight older subjects."2.67Aging and cardiovascular responsiveness to beta-agonist in humans: role of changes in beta-receptor responses versus baroreflex activity. ( Leenen, FH; White, M, 1994)
" A histological analysis revealed that chronic intake of MEL diminished the age-dependent changes in the structure of muscle fibers of the left ventricle, muscle fiber swelling, and injury zones characteristic of acute cardiac failure caused by ISO."1.48Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats. ( Akatov, V; Baburina, Y; Fadeeva, I; Krestinina, O; Kruglov, A; Odinokova, I; Sotnikova, L; Zvyagina, A, 2018)
"While Huntington's disease (HD) is classified as a neurological disorder, HD patients exhibit a high incidence of cardiovascular events leading to heart failure and death."1.43Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease. ( Colwell, CS; Coppola, G; Fishbein, MC; Gao, F; Ghiani, CA; Jordan, MC; Park, S; Roos, KP; Schroeder, AM; Wang, HB, 2016)
"Isoproterenol (10(-4)M) was infused for 20 min, 4h 10 min after the beginning of the perifusion."1.33Old rats are more sensitive to photoperiodic changes. A study on pineal melatonin. ( Charbuy, H; Djeridane, Y; Touitou, Y, 2005)
"isoproterenol were not reduced in 24-m."1.33Differential effects of aging on fluid intake in response to hypovolemia, hypertonicity, and hormonal stimuli in Munich Wistar rats. ( Denton, DA; Mathai, ML; McKinley, MJ; Thomas, CJ; Woods, RL, 2006)
"Ventricular tachyarrhythmias were initiated in TG mice by programmed stimulation but not in WT and were accelerated by isoproterenol."1.32Electrophysiological consequences of human IKs channel expression in adult murine heart. ( Cabo, C; Chiello Tracy, C; Coromilas, J; Kass, RS; Kurokawa, J; Wit, AL, 2003)
"Treatment with isoproterenol on PN2-5 did not result in any significant changes in G(s)alpha expression but robustly decreased G(i)alpha1,2."1.31Ontogeny of G-protein expression: control by beta-adrenoceptors. ( Seidler, FJ; Slotkin, TA; Zeiders, JL, 2000)
"Nicotine is a neuroteratogen that targets synaptic function during critical developmental stages and recent studies indicate that CNS vulnerability extends into adolescence, the age at which smoking typically commences."1.31Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase. ( Cousins, MM; Seidler, FJ; Slikker, W; Slotkin, TA; Xu, Z, 2002)
" There was a significant decrease with age in the maximal relaxation to cholera toxin as well as a rightward shift in the dose-response curve."1.30Impaired cholera toxin relaxation with age in rat aorta. ( Chapman, J; Mader, SL; Schutzer, WE; Watts, VJ, 1999)
"Isoproterenol pretreatment failed to cause beta-receptor down-regulation in 6-d-old animals, but by 15 d of age, down-regulation was detected along with slight desensitization of the cyclase response."1.29Atypical regulation of hepatic adenylyl cyclase and adrenergic receptors during a critical developmental period: agonists evoke supersensitivity accompanied by failure of receptor down-regulation. ( Galluzzo, JM; McCook, EC; Seidler, FJ; Slotkin, TA; Thai, L, 1996)
"Isoproterenol stimulation was reduced markedly in passaged cells."1.28Beta-adrenergic responsiveness in cultured aorta smooth muscle cells. Effects of subculture and aging. ( Borst, SE; Crass, MF; Scarpace, PJ, 1992)
" Dose-response curves for bradykinin were constructed using the dorsal hand vein compliance technique in veins preconstricted with phenylephrine in 27 volunteers (16 male, 11 female) aged 18 to 81 years."1.28Bradykinin-induced venodilation is not impaired with aging in humans. ( Blaschke, TF; Dachman, WD; Ford, GA; Hoffman, BB, 1992)
"coli, a fever was evident in 2."1.28The association of E. coli peritonitis with an impaired and delayed fever response in senescent rats. ( Bender, BS; Borst, SE; Scarpace, PJ, 1992)
" Isoproterenol-stimulated dose-response activation of adenylate cyclase was unchanged between 3 and 12 months but decreased at 24 months (p less than ."1.28Beta-adrenergic signal transduction in aging parotid and submandibular salivary glands. ( Rajakumar, G; Scarpace, PJ, 1991)
"Certain clinical manifestations of Parkinson's disease (PD) (speech or/and balance disturbances) are not linked to brain dopamine deficiency."1.28Cardiac beta-adrenoceptor sensitivity and Parkinson's disease. ( Allain, H; Bentue-Ferrer, D; Decombe, R; Lemaitre, MH; Martinet, JP; Milon, D, 1991)
" Dose-response curves showed that in foetal rat hepatocytes glucose release was already increased by 10(-8) M isoproterenol, whereas in female rat hepatocytes at least 10(-6) M isoproterenol was required."1.28Differences in the accessibility of the beta-adrenergic receptor in isolated hepatocytes from foetal and adult rats. ( Dettmer, D; Hermsdorf, T; Hofmann, E, 1991)
"Isoproterenol (IPR) was given to mice 27 and 29 months old to assess whether levels of mucin could be restored to levels similar to those in younger mice."1.28Increased mucin levels in submandibular glands of aged male mice after chronic isoproterenol treatment. ( Denny, PA; Denny, PC; Klauser, DK; Villa, BJ, 1991)
" This dosage regimen of dexamethasone also suppressed renal cyclic AMP responses to isoproterenol, but exposure to a lower dose (0."1.28Dose-dependent effect of prenatal dexamethasone treatment on beta-adrenergic receptor coupling to ornithine decarboxylase and cyclic AMP. ( Bartolome, J; Bartolome, M; Bian, XP; Kavlock, RJ; Seidler, FJ; Slotkin, TA, 1990)
"Both isoproterenol and ACTH were significantly less effective in promoting cAMP accumulation in adipocytes isolated from 12-mo-old rats."1.27Age-related decrement in hormone-stimulated lipolysis. ( Chang, H; Farahbakhsh, ZT; Hoffman, BB; Reaven, GM, 1984)
"Adenosine deaminase was added to media containing the adipocytes from older rats to remove endogenous adenosine."1.27Inhibition of lipolysis by adenosine is potentiated with age. ( Chang, H; Farahbakhsh, Z; Hoffman, BB; Reaven, G, 1984)
" The dose-response curves were shifted to the right with advancing age, suggesting reduced beta-agonist potency of the maturing tissue."1.27Postnatal development of beta-adrenergic response in ventricular muscle of the rat heart. ( Vornanen, M, 1988)
" Dose-response curves of isoproterenol revealed a progressive increase in the activation constant (Kact) with advancing age."1.27Age-related reduction of beta-adrenoceptor sensitivity in rat heart occurs by multiple mechanisms. ( Banerjee, SP; Fan, TH, 1985)
" Cumulative dose-response curves of plasma cyclic AMP concentration obtained in another group of rats after successive subcutaneous injections of isoproterenol showed that the ED50 value of this drug was higher in SHR than in WKY and increased in a parallel manner in the two strains between 7 and 18 weeks of age (respectively from 0."1.27Age-related changes of in vivo beta-adrenergic responsiveness in normotensive and spontaneously hypertensive rats. ( Bucher, B; Heitz, C; Stoclet, JC, 1984)
"Isoproterenol pretreatment (1 mg/kg s."1.27Age-dependent changes in electrophysiologic characteristics of fast and slow action potentials in rat papillary muscle. ( Balazs, T; Ehrreich, S; Johnson, G; Kojima, M; Sperelakis, N, 1983)
" Results were similar for isoproterenol, although the positive inotropic effect occurred over a wider dosage range for this drug."1.27Milrinone effects in the isolated immature rabbit heart. ( Ayres, N; Brannon, TS; Fixler, DE; Parrish, MD; Payne, A, 1988)
" The release of free acids (FFA) into the incubation medium was measured after addition of increasing concentrations of catecholamines and the dose-response curves were evaluated."1.26Responsiveness of the trimmed rat subcutaneous adipose tissue beta-receptors to catecholamines in ontogenesis. ( Mourek, J; Mühlbachová, E, 1982)
"Isoproterenol was infused in doses of 0."1.26The comparative hemodynamic effects of isoproterenol in chronically instrumented puppies and adult dogs. ( Driscoll, DJ; Entman, ML; Fukushige, J; Hartley, CJ; Lewis, RM, 1981)
"3."1.26Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the pre-weanling rat. ( Seidler, FJ; Slotkin, TA, 1979)
" The mean log dose-response curve for the elderly group was displaced to the right and the mean maximum response was less than that for the young subjects."1.26Age and beta adrenoceptor-mediated function. ( Chung, S; Dillon, N; Kelly, J; O'Malley, K, 1980)
" No age differences were seen in the time course of amylase release following (-)-isoproterenol stimulation or in the (-)-isoproterenol dose-response curve."1.26Beta-adrenergic regulation of rat parotid gland exocrine protein secretion during aging. ( Baum, BJ; Ito, H; Roth, GS, 1981)

Research

Studies (515)

TimeframeStudies, this research(%)All Research%
pre-1990241 (46.80)18.7374
1990's190 (36.89)18.2507
2000's54 (10.49)29.6817
2010's26 (5.05)24.3611
2020's4 (0.78)2.80

Authors

AuthorsStudies
Yáñez-Bisbe, L1
Garcia-Elias, A1
Tajes, M1
Almendros, I1
Rodríguez-Sinovas, A1
Inserte, J1
Ruiz-Meana, M1
Farré, R1
Farré, N1
Benito, B1
Holmuhamedov, EL1
Chakraborty, P1
Oberlin, A1
Liu, X1
Yousufuddin, M1
Shen, WK1
Terzic, A1
Jahangir, A1
Hardy, CC1
Keilich, SR1
Harrison, AG1
Knight, BE1
Baker, DS1
Smith, PP1
Gan, M1
Zhang, S1
Fan, Y1
Tan, Y1
Guo, Z1
Chen, L1
Bai, L1
Jiang, D1
Hao, X1
Li, X1
Shen, L1
Zhu, L1
Cao, H1
Hu, Y1
Zhu, X1
Yao, N1
Gu, J1
Wang, Y2
Zhu, W1
Ulla, A1
Mohamed, MK1
Sikder, B1
Rahman, AT1
Sumi, FA1
Hossain, M1
Reza, HM1
Rahman, GMS1
Alam, MA1
Hardy, RN1
Simsek, ZD1
Curry, B1
Core, SL1
Beltz, T1
Xue, B1
Johnson, AK2
Thunhorst, RL2
Curtis, KS1
Odinokova, I1
Baburina, Y1
Kruglov, A1
Fadeeva, I1
Zvyagina, A1
Sotnikova, L1
Akatov, V1
Krestinina, O1
Fu, YC1
Chen, R1
Chen, MY1
Chen, Y1
Wang, YL1
Xu, B1
Yang, J1
Yin, T1
Li, Y2
Morgan-Bathke, M1
Lin, HH1
Chibly, AM1
Zhang, W1
Sun, X1
Chen, CH1
Flodby, P1
Borok, Z1
Wu, R1
Arnett, D1
Klein, RR1
Ann, DK1
Limesand, KH1
Ross, AJ1
Gao, Z1
Pollock, JP1
Leuenberger, UA1
Sinoway, LI1
Muller, MD1
Carillion, A1
Feldman, S1
Jiang, C1
Atassi, F1
Na, N1
Mougenot, N1
Besse, S1
Hulot, JS1
Riou, B1
Amour, J1
Gonzalez-Valdes, I1
Hidalgo, I1
Bujarrabal, A1
Lara-Pezzi, E1
Padron-Barthe, L1
Garcia-Pavia, P1
Gómez-del Arco, P1
Gomez, P1
Redondo, JM1
Ruiz-Cabello, JM1
Jimenez-Borreguero, LJ1
Enriquez, JA1
de la Pompa, JL1
Hidalgo, A1
Gonzalez, S1
Fernandois, D1
Na, E1
Cuevas, F1
Cruz, G1
Lara, HE1
Paredes, AH1
Schroeder, AM1
Wang, HB1
Park, S1
Jordan, MC1
Gao, F2
Coppola, G1
Fishbein, MC1
Roos, KP1
Ghiani, CA1
Colwell, CS1
Yaniv, Y1
Ahmet, I1
Tsutsui, K1
Behar, J1
Moen, JM1
Okamoto, Y1
Guiriba, TR1
Liu, J1
Bychkov, R1
Lakatta, EG6
Wang, J1
Song, Y1
Li, H1
Shen, Q1
Shen, J1
An, X1
Wu, J1
Zhang, J2
Wu, Y1
Xiao, H2
Zhang, Y1
Gergs, U1
Neumann, J1
Simm, A1
Silber, RE1
Remmers, FO1
Läer, S1
Bellinger, DL1
Silva, D1
Millar, AB1
Molinaro, C1
Ghamsary, M1
Carter, J1
Perez, S1
Lorton, D1
Lubahn, C1
Araujoa, G1
Thyagarajan, S1
Mongue-Din, H1
Salmon, A1
Fiszman, MY1
Fromes, Y1
Yuan, Q1
Han, P1
Dong, M1
Ren, X1
Zhou, X1
Chen, S1
Jones, WK1
Chu, G1
Wang, HS1
Kranias, EG2
Maier, T1
Schreckenberg, R1
Schlüter, KD1
Terrien, J1
Ambid, L1
Nibbelink, M1
Saint-Charles, A1
Aujard, F1
Salameh, A1
Dhein, S1
Fleischmann, B1
Grohe, C1
Hescheler, J1
Linz, KW1
Meyer, R1
Zhang, YY1
Du, XJ2
Lu, ZZ1
Koyanagi, Y1
Yamamoto, K1
Oi, Y1
Koshikawa, N1
Kobayashi, M1
Sarma, S1
Li, N1
van Oort, RJ1
Reynolds, C1
Skapura, DG1
Wehrens, XH1
Grobe, CL1
Beltz, TG1
Muscogiuri, G1
Kamat, A2
Balas, B1
Giaccari, A1
Defronzo, RA1
Musi, N1
Katz, MS3
Durgan, DJ1
Tsai, JY1
Grenett, MH1
Pat, BM1
Ratcliffe, WF1
Villegas-Montoya, C1
Garvey, ME1
Nagendran, J1
Dyck, JR1
Bray, MS1
Gamble, KL1
Gimble, JM1
Young, ME1
Tang, T1
Hammond, HK1
Firth, A1
Yang, Y1
Gao, MH1
Yuan, JX1
Lai, NC1
Liles, JT1
Ida, KK1
Joly, KM1
Chapo, J1
Plato, CF1
Owen, SJ1
Massa, HH1
Rose'Meyer, RB1
Jackson, MF1
Luong, D1
Vang, DD1
Garikipati, DK1
Stanton, JB1
Nelson, OL1
Rodgers, BD1
Ghosh, PM1
Shu, ZJ1
Zhu, B1
Lu, Z1
Ikeno, Y1
Barnes, JL1
Yeh, CK1
Zhang, BX1
Baamonde, C1
Lumbreras, MA1
MartInez-Cué, C1
Vallina, IF1
Flórez, J1
Dierssen, M3
Xu, Z1
Seidler, FJ9
Cousins, MM1
Slikker, W1
Slotkin, TA12
Chiello Tracy, C1
Cabo, C1
Coromilas, J1
Kurokawa, J1
Kass, RS1
Wit, AL1
Prakash, YS1
Hunter, LW1
Seckin, I1
Sieck, GC1
Novotny, J2
Hrbasová, M1
Kolár, F1
Svoboda, P2
Dun, W1
Yagi, T1
Rosen, MR6
Boyden, PA1
Djeridane, Y2
Khavinson, VKh1
Anisimov, VN1
Touitou, Y2
Takagi, G1
Asai, K1
Vatner, SF1
Kudej, RK1
Rossi, F2
Peppas, A1
Takagi, I1
Resuello, RR1
Natividad, F1
Shen, YT1
Vatner, DE1
Tugay, M1
Yildiz, F1
Utkan, T1
Gacar, N1
Ulak, G1
Erden, F1
Rebola, N1
Sebastião, AM1
de Mendonca, A1
Oliveira, CR1
Ribeiro, JA1
Cunha, RA1
RONA, G1
CHAPPEL, CI1
BALAZS, T2
GAUDRY, R1
Tipparaju, SM1
Kumar, R5
Joyner, RW5
Wagner, MB1
Watters, JM1
Reis, GF1
Lee, MB1
Huang, AS1
Parfitt, KD2
Charbuy, H1
Stöhr, J1
Sugizaki, MM1
Carvalho, RF1
Aragon, FF1
Padovani, CR1
Okoshi, K1
Okoshi, MP1
Zanati, SG1
Pai-Silva, MD1
Novelli, EL1
Cicogna, AC1
Li, D1
Qu, Y1
Tao, L1
Liu, H1
Hu, A2
Sharifi-Azad, S2
Grunwald, Z2
Ma, XL2
Sun, JZ2
Maruyama, R1
Takemura, G1
Tohse, N1
Ohkusa, T1
Ikeda, Y1
Tsuchiya, K1
Minatoguchi, S1
Matsuzaki, M1
Fujiwara, T1
Fujiwara, H1
Castillo, C1
Cruzado, M1
Ariznavarreta, C1
Gil-Loyzaga, P1
Lahera, V1
Cachofeiro, V1
Tresguerres, JA1
McKinley, MJ1
Denton, DA1
Thomas, CJ1
Woods, RL1
Mathai, ML1
Martin, SR1
Emanuel, K1
Sears, CE1
Zhang, YH1
Casadei, B1
Schutzer, WE3
Xue, H2
Reed, JF2
Mader, SL5
Donato, AJ1
Lesniewski, LA1
Delp, MD1
Madden, KM1
Levy, WC3
Stratton, JR4
Baloğlu, E1
Kiziltepe, O1
Gürdal, H1
Kang, KB2
Rajanayagam, MA1
van der Zypp, A2
Majewski, H2
Leosco, D1
Rengo, G1
Iaccarino, G1
Filippelli, A2
Lymperopoulos, A1
Zincarelli, C1
Fortunato, F1
Golino, L1
Marchese, M1
Esposito, G1
Rapacciuolo, A1
Rinaldi, B1
Ferrara, N3
Koch, WJ2
Rengo, F2
Iwatsubo, K1
Suzuki, S1
Li, C1
Tsunematsu, T1
Nakamura, F1
Okumura, S1
Sato, M1
Minamisawa, S1
Toya, Y1
Umemura, S1
Ishikawa, Y3
Farrell, SR1
Howlett, SE1
Jiao, X1
Gao, E1
Bucher, B1
Heitz, C1
Stoclet, JC4
Oppenheim, G1
Mintzer, J1
Halperin, Y1
Eliakim, R1
Stessman, J1
Ebstein, RP1
Hoffman, BB15
Chang, H3
Farahbakhsh, Z1
Reaven, G1
Piantanelli, L3
Muzzioli, M1
Fabris, N1
Guarnieri, T1
Filburn, CR1
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Mather, JP1
Burchill, SA1
Thody, AJ1
Ehrén, H1
Bolme, P1
Haun, SE1
Korkushko, OV1
Moroz, GZ1
Toma, BS1
Wangler, RD1
Sparks, HV1
Brannon, TS1
Payne, A1
Ayres, N1
Fixler, DE1
Jullien, T1
Verdetti, J1
Yokota, Y1
Chou, HT1
Tsumura, Y1
Takeuchi, Y1
Usuki, S1
Fukuzaki, H1
Takarada, A1
Yoshida, Y1
Shaw, PA1
Cox, JL1
Barka, T2
Naito, Y1
Artman, M1
Kithas, PA1
Wike, JS1
Strada, SJ1
De-Moraes, S1
Okamura, T1
Miyazaki, M2
Shimizu, I2
Lee, TJ1
Shirasaki, Y1
Nickols, GA1
Johnson, JM1
Stevens, LM1
Landis, SC1
Dontsov, VI1
Toraason, M1
Stringer, B1
Smith, R1
Gillard, M1
Waelbroeck, M1
Housman, A1
Owen, TL1
Mardini, IA1
Schlenker, EH1
Burbach, JA1
Spinelli, W1
Danilo, P1
Buchthal, SD1
Posner, P1
Baker, SP1
Hunter, B1
Walker, DW1
Rudolph, AM1
Yuwiler, A1
Martin, JR1
Fuchs, A1
Harting, J1
Byrne, NG1
Hirst, GD1
Large, WA1
Perkins, JP1
Moore, MM1
Freis, ED1
Heath, WC1
Luchsinger, PC1
Snell, RE1
Van der Noen, H1
Löffelholz, K1
Jo, JS1
Ishihara, N1
Kikuchi, G1
Simpson, LL1
Seelig, MS1
Aberg, G1
Adler, G1
Karoly, K1
Britton, VJ1
Müller, E1
Pearse, AG1
Moss, DW1
Shibata, S1
Kuchii, M1
Kurahashi, K1
Robelli, F1
De Vita, C1
Cadel, A1
Geber, WF1
Schwinghamer, JM1
Siro-Brigiani, G1
Chieppa, D1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00005284]0 participants Observational1985-01-31Completed
[NCT00005282]0 participants Observational1981-12-31Completed
[NCT00005298]0 participants Observational1990-07-31Completed
Effects of Insulin on Hypotension and Sarcopenia[NCT03248271]0 participants (Actual)Observational2017-10-01Withdrawn (stopped due to Study design was changed to the study was changed to Insulin, hypotension and sarcopenia.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for isoproterenol and Aging

ArticleYear
Beta-adrenergic receptors: biochemical mechanisms of physiological regulation.
    Physiological reviews, 1984, Volume: 64, Issue:2

    Topics: Adenylyl Cyclases; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; A

1984
Sympathetic nervous system and aging in man.
    Endocrine reviews, 1980,Spring, Volume: 1, Issue:2

    Topics: Adolescent; Adrenal Medulla; Adult; Aged; Aging; Animals; Blood Pressure; Child; Circadian Rhythm; C

1980
Myocardial aging: functional alterations and related cellular mechanisms.
    The American journal of physiology, 1982, Volume: 242, Issue:6

    Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Cardiac Glycosides; Cardiomegaly; Coronary Circulat

1982
Adrenoceptor function and ageing.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:5

    Topics: Adult; Aged; Aging; Animals; Cyclic AMP; Guinea Pigs; Heart Rate; Humans; In Vitro Techniques; Isopr

1984
Aging and hormone-sensitive lipolysis: reconciling the literature.
    Journal of gerontology, 1994, Volume: 49, Issue:4

    Topics: Adenosine; Aging; Animals; Cyclic AMP; Epinephrine; Isoproterenol; Lipolysis; Rats; Rats, Inbred Str

1994
Dynamics of n-3 and n-6 fatty acids in phospholipids of heart muscle.
    Journal of internal medicine. Supplement, 1989, Volume: 731

    Topics: Aging; Animals; Animals, Newborn; Catecholamines; Death, Sudden; Dietary Fats; Fatty Acids, Unsatura

1989

Trials

11 trials available for isoproterenol and Aging

ArticleYear
β-Adrenergic receptor blockade impairs coronary exercise hyperemia in young men but not older men.
    American journal of physiology. Heart and circulatory physiology, 2014, Nov-15, Volume: 307, Issue:10

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aging; Coronary Ves

2014
Cardiac sensitivity to isoprenaline, lymphocyte beta-adrenoceptors and age.
    Clinical science (London, England : 1979), 1984, Volume: 66, Issue:6

    Topics: Adult; Aging; Cyclic AMP; Heart Rate; Humans; Isoproterenol; Lymphocytes; Middle Aged; Receptors, Ad

1984
Age-dependent changes in the beta-adrenoceptor-G-protein(s)-adenylyl cyclase system in human right atrium.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1

    Topics: Adenylyl Cyclases; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Blot

1995
Effects of age and hypertension on adrenoceptor-sensitivity evaluated with CD25 and QT/QS2.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50A, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Electrocardiography; Female; Heart Rate; Humans; Hypertension

1995
Aging and cardiovascular responsiveness to beta-agonist in humans: role of changes in beta-receptor responses versus baroreflex activity.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:5

    Topics: Adult; Aged; Aging; Atropine; Baroreflex; Female; Forearm; Heart Rate; Hemodynamics; Humans; Isoprot

1994
Influence of age on venodilator effect of isoproterenol and amrinone.
    European journal of clinical pharmacology, 1996, Volume: 50, Issue:1-2

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Amrinone; Blood Pressure; Cross-Ove

1996
Age, hypertension, and cardiac responses to beta-agonist in humans.
    Clinical pharmacology and therapeutics, 1998, Volume: 63, Issue:6

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Antihypertensive Agents; Blood Pressure; Catecholamine

1998
Effects of age and gender on the cardiovascular responses to isoproterenol.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1999, Volume: 54, Issue:9

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Cardiovascular System; Female; Humans; Isoproterenol;

1999
Adipose tissue metabolism in young and middle-aged men after control for total body fatness.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:7

    Topics: Adipose Tissue; Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Agonists;

2000
Evidence for agonist-specific endothelial vasodilator dysfunction with ageing in healthy humans.
    The Journal of physiology, 2002, Jul-01, Volume: 542, Issue:Pt 1

    Topics: Acetylcholine; Adrenergic beta-Agonists; Adult; Aged; Aging; Blood Pressure; Body Composition; Brady

2002
Comparison of hypokalaemic, electrocardiographic and haemodynamic responses to inhaled isoprenaline and salbutamol in young and elderly subjects.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:3

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Aging; Albuterol; Dose-Response Relation

1991

Other Studies

498 other studies available for isoproterenol and Aging

ArticleYear
Aging Impairs Reverse Remodeling and Recovery of Ventricular Function after Isoproterenol-Induced Cardiomyopathy.
    International journal of molecular sciences, 2021, Dec-24, Volume: 23, Issue:1

    Topics: Aging; Animals; Cardiomyopathies; Collagen; Disease Models, Animal; Female; Fibrosis; Gene Expressio

2021
Aging-associated susceptibility to stress-induced ventricular arrhythmogenesis is attenuated by tetrodotoxin.
    Biochemical and biophysical research communications, 2022, 10-01, Volume: 623

    Topics: 4-Aminopyridine; Action Potentials; Aging; Animals; Arrhythmias, Cardiac; Isoproterenol; Male; Myocy

2022
The aging bladder phenotype is not the direct consequence of bladder aging.
    Neurourology and urodynamics, 2019, Volume: 38, Issue:8

    Topics: Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Fem

2019
The Expression of microRNA in Adult Rat Heart with Isoproterenol-Induced Cardiac Hypertrophy.
    Cells, 2020, 05-08, Volume: 9, Issue:5

    Topics: Aging; Animals; Atrial Natriuretic Factor; Base Sequence; Cardiomegaly; Gene Expression Regulation,

2020
O-GlcNAc transferase affects the signal transduction of β1 adrenoceptor in adult rat cardiomyocytes by increasing the O-GlcNAcylation of β1 adrenoceptor.
    Biochemical and biophysical research communications, 2020, 07-12, Volume: 528, Issue:1

    Topics: Adenoviridae; Aging; Animals; Calcium; Calcium-Binding Proteins; Cell Death; Cyclic AMP; Cyclic AMP-

2020
Coenzyme Q10 prevents oxidative stress and fibrosis in isoprenaline induced cardiac remodeling in aged rats.
    BMC pharmacology & toxicology, 2017, 04-20, Volume: 18, Issue:1

    Topics: Aging; Animals; Fibrosis; Isoproterenol; Male; Oxidative Stress; Rats; Rats, Long-Evans; Ubiquinone;

2017
Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats.
    Physiology & behavior, 2018, 08-01, Volume: 192

    Topics: Adrenergic beta-Agonists; Aging; Animals; Astrocytes; Brain; Drinking; Drinking Water; Female; Isopr

2018
Effect of Melatonin on Rat Heart Mitochondria in Acute Heart Failure in Aged Rats.
    International journal of molecular sciences, 2018, 05-23, Volume: 19, Issue:6

    Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Aging; Animals; Calcium; Cell Respiration; Cryoultrami

2018
[Age-related changes in transient outward potassium current of rat ventricular myocyte].
    Sheng li xue bao : [Acta physiologica Sinica], 2013, Apr-25, Volume: 65, Issue:2

    Topics: 4-Aminopyridine; Aging; Animals; Cells, Cultured; Heart Ventricles; Isoproterenol; Myocytes, Cardiac

2013
Deletion of ATG5 shows a role of autophagy in salivary homeostatic control.
    Journal of dental research, 2013, Volume: 92, Issue:10

    Topics: Acinar Cells; Aging; Amylases; Animals; Apoptosis; Aquaporin 5; Autophagy; Autophagy-Related Protein

2013
Overexpression of cyclic adenosine monophosphate effluent protein MRP4 induces an altered response to β-adrenergic stimulation in the senescent rat heart.
    Anesthesiology, 2015, Volume: 122, Issue:2

    Topics: Adrenergic beta-Agonists; Aging; Animals; Arterial Pressure; Bronchodilator Agents; Calcium; Echocar

2015
Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.
    Nature communications, 2015, Mar-09, Volume: 6

    Topics: Aging; Animals; Cardiomyopathy, Dilated; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16;

2015
Kisspeptin is involved in ovarian follicular development during aging in rats.
    The Journal of endocrinology, 2016, Volume: 228, Issue:3

    Topics: Aging; Animals; Female; Gene Expression; Isoproterenol; Kisspeptins; Ovarian Follicle; Ovary; Ovulat

2016
Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Adrenergic beta-Agonists; Aging; Animals; Apoptosis; Cardiomegaly; Disease Models, Animal; Fibrosis;

2016
Deterioration of autonomic neuronal receptor signaling and mechanisms intrinsic to heart pacemaker cells contribute to age-associated alterations in heart rate variability in vivo.
    Aging cell, 2016, Volume: 15, Issue:4

    Topics: Aging; Animals; Autonomic Nervous System; Carbachol; Heart Rate; Isoproterenol; Longevity; Mice, Inb

2016
Exacerbated cardiac fibrosis induced by β-adrenergic activation in old mice due to decreased AMPK activity.
    Clinical and experimental pharmacology & physiology, 2016, Volume: 43, Issue:11

    Topics: Adrenergic beta-Agonists; Aging; AMP-Activated Protein Kinases; Animals; Fibrosis; Heart; Isoprotere

2016
Phosphorylation of phospholamban and troponin I through 5-HT4 receptors in the isolated human atrium.
    Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 379, Issue:4

    Topics: Aged; Aging; Atrial Function; Calcium-Binding Proteins; Cyclic AMP; Electric Stimulation; Female; Ge

2009
Sympathetic nervous system and lymphocyte proliferation in the Fischer 344 rat spleen: a longitudinal study.
    Neuroimmunomodulation, 2008, Volume: 15, Issue:4-6

    Topics: 1-Methyl-3-isobutylxanthine; Aging; alpha-Methyltyrosine; Animals; Concanavalin A; Cyclic AMP; Cytok

2008
Periodic variation in R-R intervals and cardiovascular autonomic regulation in young adult Syrian hamsters.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 296, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Anti-Arrhythmia Agents; Atrop

2009
Partial downregulation of junctin enhances cardiac calcium cycling without eliciting ventricular arrhythmias in mice.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Aging; Animals; Arrhythmias, Cardiac; Caffeine; Calcium Signaling; Calcium-Binding Proteins; Disease

2009
Effect of preischemic beta-adrenoceptor stimulation on postischemic contractile dysfunction.
    Life sciences, 2009, Mar-27, Volume: 84, Issue:13-14

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Female; Hemodynamics; Hyperte

2009
Non-shivering thermogenesis activation and maintenance in the aging gray mouse lemur (Microcebus murinus).
    Experimental gerontology, 2010, Volume: 45, Issue:6

    Topics: Adaptation, Physiological; Adipose Tissue, Brown; Age Factors; Aging; Animals; Arousal; Blotting, We

2010
The aging heart: changes in the pharmacodynamic electrophysiological response to verapamil in aged rabbit hearts.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:2

    Topics: Age Factors; Aging; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Carbachol; Electrop

2010
Developmental changes in the geometry, function and responsiveness of the mouse heart to beta-adrenergic stimulation as determined by high-resolution echocardiography.
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:8

    Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Echocardiography; Exercise Test; Heart;

2010
Presynaptic interneuron subtype- and age-dependent modulation of GABAergic synaptic transmission by beta-adrenoceptors in rat insular cortex.
    Journal of neurophysiology, 2010, Volume: 103, Issue:5

    Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Cerebral Cor

2010
Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jul-20, Volume: 107, Issue:29

    Topics: Aging; Animals; Calcium; Cardiomyopathies; Cyclic AMP-Dependent Protein Kinases; Death, Sudden; Fibr

2010
Effects of β-adrenergic receptor agonists on drinking and arterial blood pressure in young and old rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 300, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Albuterol; Animals; Blood Pressure; Dr

2011
β-Adrenergic Responsive Induction of Insulin Resistance in Liver of Aging Rats.
    Endocrine research, 2011, Volume: 36, Issue:2

    Topics: Adrenergic beta-Agonists; Aging; Animals; Glucose; Insulin; Insulin Resistance; Insulin Secretion; I

2011
Evidence suggesting that the cardiomyocyte circadian clock modulates responsiveness of the heart to hypertrophic stimuli in mice.
    Chronobiology international, 2011, Volume: 28, Issue:3

    Topics: Aging; Animals; Body Temperature; Cardiomegaly; Cardiotonic Agents; Circadian Clocks; CLOCK Proteins

2011
Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged hearts.
    Journal of the American College of Cardiology, 2011, May-03, Volume: 57, Issue:18

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Calcium; Calcium-Binding Proteins; Cycl

2011
Age exacerbates chronic catecholamine-induced impairments in contractile reserve in the rat.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:2

    Topics: Aging; Animals; Cardiotonic Agents; Catecholamines; Digoxin; Drug Administration Schedule; Isoproter

2011
Loss of adenosine A2B receptor mediated relaxant responses in the aged female rat bladder; effects of dietary phytoestrogens.
    Naunyn-Schmiedeberg's archives of pharmacology, 2012, Volume: 385, Issue:5

    Topics: Adenosine-5'-(N-ethylcarboxamide); Adrenergic beta-Agonists; Aging; Animals; Carbachol; Diet; Estrog

2012
The aging myostatin null phenotype: reduced adiposity, cardiac hypertrophy, enhanced cardiac stress response, and sexual dimorphism.
    The Journal of endocrinology, 2012, Volume: 213, Issue:3

    Topics: Adipose Tissue, Brown; Adiposity; Aging; Animals; Bone Density; Cardiomegaly; Cardiotonic Agents; Fe

2012
Role of β-adrenergic receptors in regulation of hepatic fat accumulation during aging.
    The Journal of endocrinology, 2012, Volume: 213, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Cells, Cul

2012
Postnatal handling induces long-term modifications in central beta-noradrenergic signalling in rats.
    Stress (Amsterdam, Netherlands), 2002, Volume: 5, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Cerebellum;

2002
Adolescent nicotine administration alters serotonin receptors and cell signaling mediated through adenylyl cyclase.
    Brain research, 2002, Oct-04, Volume: 951, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Brain Chemistry; Colforsin; Female; GTP

2002
Electrophysiological consequences of human IKs channel expression in adult murine heart.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:1

    Topics: Adrenergic beta-Agonists; Aging; Animals; Blood Pressure; Cardiac Pacing, Artificial; Delayed Rectif

2003
Volatile anesthetics and regulation of cardiac Na+/Ca2+ exchange in neonates versus adults.
    Annals of the New York Academy of Sciences, 2002, Volume: 976

    Topics: Aging; Anesthetics, Inhalation; Animals; Animals, Newborn; Calcium; Halothane; Heart; Heart Ventricl

2002
Cardiomegaly induced by pressure overload in newborn rats is accompanied by altered expression of the long isoform of G(s)alpha protein and deranged signaling of adenylyl cyclase.
    Molecular and cellular biochemistry, 2003, Volume: 245, Issue:1-2

    Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Cardiomegaly; Cardiotonic Agents; Colforsin; Fl

2003
Calcium and potassium currents in cells from adult and aged canine right atria.
    Cardiovascular research, 2003, Jun-01, Volume: 58, Issue:3

    Topics: Action Potentials; Adrenergic beta-Agonists; Aging; Animals; Barium; Calcium; Calcium Channels; Chel

2003
Effect of a synthetic pineal tetrapeptide (Ala-Glu-Asp-GLy) on melatonin secretion by the pineal gland of young and old rats.
    Journal of endocrinological investigation, 2003, Volume: 26, Issue:3

    Topics: Adrenergic beta-Agonists; Aging; Animals; In Vitro Techniques; Isoproterenol; Male; Melatonin; Oligo

2003
Gender differences on the effects of aging on cardiac and peripheral adrenergic stimulation in old conscious monkeys.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:2

    Topics: Aging; Animals; Colforsin; Consciousness; Dihydropyridines; Female; Isoproterenol; Macaca fascicular

2003
Age-related smooth muscle reactivity changes in the rat bladder: an in vitro study.
    Pharmacological research, 2003, Volume: 48, Issue:4

    Topics: Adenosine Triphosphate; Aging; Animals; Carbachol; Dose-Response Relationship, Drug; In Vitro Techni

2003
Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged rats.
    Journal of neurophysiology, 2003, Volume: 90, Issue:2

    Topics: Adenosine; Adrenergic beta-Agonists; Aging; Animals; Blotting, Western; Cyclic AMP; Electrophysiolog

2003
The effect of breed, age, and sex on myocardial necrosis produced by isoproterenol in the rat.
    Journal of gerontology, 1959, Volume: 14, Issue:2

    Topics: Aging; Animals; Cardiomyopathies; Disease; Heart Diseases; Isoproterenol; Myocardial Infarction; Myo

1959
Developmental differences in L-type calcium current of human atrial myocytes.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:5

    Topics: Adolescent; Adrenergic beta-Agonists; Aged; Aging; Calcium Channels, L-Type; Cyclic AMP; Electrophys

2004
Insulin responses to glucose and isoproterenol decrease with age.
    Canadian journal of surgery. Journal canadien de chirurgie, 2005, Volume: 48, Issue:2

    Topics: Adrenergic beta-Agonists; Adult; Aging; Female; Glucose; Glucose Clamp Technique; Glucose Intoleranc

2005
Adenylate cyclase-mediated forms of neuronal plasticity in hippocampal area CA1 are reduced with aging.
    Journal of neurophysiology, 2005, Volume: 93, Issue:6

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Aging; Analysis of Variance; Animals; Colf

2005
Old rats are more sensitive to photoperiodic changes. A study on pineal melatonin.
    Experimental gerontology, 2005, Volume: 40, Issue:5

    Topics: Adrenergic beta-Agonists; Aging; Animals; Isoproterenol; Male; Melatonin; Photoperiod; Pineal Gland;

2005
Characterization of [3H]-forskolin binding sites in young and adult rat brain cortex: identification of suramin as a competitive inhibitor of [3H]-forskolin binding.
    Canadian journal of physiology and pharmacology, 2005, Volume: 83, Issue:7

    Topics: Adrenergic beta-Agonists; Aging; Animals; Baclofen; Binding, Competitive; Cell Membrane; Cerebral Co

2005
Myocardial dysfunction induced by food restriction is related to morphological damage in normotensive middle-aged rats.
    Journal of biomedical science, 2005, Volume: 12, Issue:4

    Topics: Aging; Animal Feed; Animals; Body Weight; Calcium; Calcium Chloride; Echocardiography; Food Deprivat

2005
Inhibition of iNOS protects the aging heart against beta-adrenergic receptor stimulation-induced cardiac dysfunction and myocardial ischemic injury.
    The Journal of surgical research, 2006, Volume: 131, Issue:1

    Topics: Adrenergic beta-Agonists; Aging; Animals; Isoproterenol; Male; Myocardial Infarction; Myocardial Isc

2006
Synchronous progression of calcium transient-dependent beating and sarcomere destruction in apoptotic adult cardiomyocytes.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:4

    Topics: Adrenergic beta-Agonists; Aging; Animals; Apoptosis; Calcium; Calcium Signaling; Cells, Cultured; Is

2006
Effect of recombinant human growth hormone administration on body composition and vascular function and structure in old male Wistar rats.
    Biogerontology, 2005, Volume: 6, Issue:5

    Topics: Acetylcholine; Adipose Tissue; Aging; Animals; Aorta, Thoracic; Body Composition; Dose-Response Rela

2005
Differential effects of aging on fluid intake in response to hypovolemia, hypertonicity, and hormonal stimuli in Munich Wistar rats.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Feb-28, Volume: 103, Issue:9

    Topics: Adrenergic beta-Agonists; Aging; Animals; Body Weight; Dehydration; Drinking; Eating; Germany; Hypov

2006
Are myocardial eNOS and nNOS involved in the beta-adrenergic and muscarinic regulation of inotropy? A systematic investigation.
    Cardiovascular research, 2006, Apr-01, Volume: 70, Issue:1

    Topics: Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cell Size; Cholinergic Agonists; Electric Stimu

2006
Effect of age on vascular beta2-adrenergic receptor desensitization is not mediated by the receptor coupling to Galphai proteins.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2006, Volume: 61, Issue:9

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Aorta; GTP

2006
Ageing and exercise training alter adrenergic vasomotor responses of rat skeletal muscle arterioles.
    The Journal of physiology, 2007, Feb-15, Volume: 579, Issue:Pt 1

    Topics: Adrenergic beta-Agonists; Aging; Animals; Arterioles; Colforsin; Enzyme Inhibitors; Hindlimb; Isopro

2007
Normal aging impairs upregulation of the beta-adrenergic but not the alpha-adrenergic response: aging and adrenergic upregulation.
    Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Clonidine; Female; Humans; Isoproterenol; Mal

2006
The role of Gi proteins in reduced vasorelaxation response to beta-adrenoceptor agonists in rat aorta during maturation.
    European journal of pharmacology, 2007, Jun-14, Volume: 564, Issue:1-3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Aorta; Cyclic AMP

2007
A role for cyclooxygenase in aging-related changes of beta-adrenoceptor-mediated relaxation in rat aortas.
    Naunyn-Schmiedeberg's archives of pharmacology, 2007, Volume: 375, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Aging; Animals; Aorta, Thoracic; Aspirin; Immunohistochemistry; Indome

2007
Exercise training and beta-blocker treatment ameliorate age-dependent impairment of beta-adrenergic receptor signaling and enhance cardiac responsiveness to adrenergic stimulation.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Blood Pres

2007
Dopamine induces apoptosis in young, but not in neonatal, neurons via Ca2+-dependent signal.
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:5

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Aging; Animals; Apoptosis; Basal Ganglia;

2007
The effects of isoproterenol on abnormal electrical and contractile activity and diastolic calcium are attenuated in myocytes from aged Fischer 344 rats.
    Mechanisms of ageing and development, 2007, Volume: 128, Issue:10

    Topics: Adrenergic beta-Agonists; Aging; Animals; Calcium; Diastole; Electrophysiology; Isoproterenol; Male;

2007
Tonic beta-adrenergic drive provokes proinflammatory and proapoptotic changes in aging mouse heart.
    Rejuvenation research, 2008, Volume: 11, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Amidines; Animals; Apoptosis; Benzylam

2008
Age-related changes of in vivo beta-adrenergic responsiveness in normotensive and spontaneously hypertensive rats.
    European journal of pharmacology, 1984, Jun-15, Volume: 102, Issue:1

    Topics: Aging; Animals; Blood Pressure; Cyclic AMP; Hypertension; Isoproterenol; Male; Propranolol; Rats; Ra

1984
Acute desensitization of lymphocyte beta-adrenergic-stimulated adenylate cyclase in old age and Alzheimer's disease.
    Life sciences, 1984, Oct-22, Volume: 35, Issue:17

    Topics: Adenylyl Cyclases; Adult; Aged; Aging; Alzheimer Disease; Cyclic AMP; Female; Humans; In Vitro Techn

1984
Inhibition of lipolysis by adenosine is potentiated with age.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:5

    Topics: Adenosine; Adenosine Deaminase; Adipose Tissue; Aging; Animals; Isoproterenol; Lipid Mobilization; M

1984
Thymus-endocrine interactions during ageing.
    Aktuelle Gerontologie, 1980, Volume: 10, Issue:5

    Topics: Aging; Animals; Biological Clocks; Endocrine Glands; Humans; Isoproterenol; Mice; Receptors, Adrener

1980
Contractile and biochemical correlates of beta-adrenergic stimulation of the aged heart.
    The American journal of physiology, 1980, Volume: 239, Issue:4

    Topics: Adrenergic beta-Agonists; Aging; Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug;

1980
Adrenergic and cholinergic mediated glucose oxidation by rat parotid gland acinar cells during aging.
    Biochemical and biophysical research communications, 1981, Jan-15, Volume: 98, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Carbachol; Cell Aggregation; Ep

1981
Selected phenotypic induction of null lymphocytes from mice with thymic and nonthymic agents.
    Cellular immunology, 1982, Sep-01, Volume: 72, Issue:1

    Topics: Aging; Animals; Antigens, Surface; Cell Differentiation; Chromosomal Proteins, Non-Histone; Cyclic A

1982
Alterations in cardiac alpha and beta adrenoceptors during the development of spontaneous hypertension.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:2

    Topics: Adrenergic alpha-Antagonists; Aging; Animals; Dihydroalprenolol; Dioxanes; Heart Ventricles; Hyperte

1984
Alterations in leukocyte beta-receptor affinity with aging. A potential explanation for altered beta-adrenergic sensitivity in the elderly.
    The New England journal of medicine, 1984, Mar-29, Volume: 310, Issue:13

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Epinephrine; Humans; Isoproterenol; Leukocytes; Male;

1984
Age-related decrement in hormone-stimulated lipolysis.
    The American journal of physiology, 1984, Volume: 247, Issue:6 Pt 1

    Topics: Adipose Tissue; Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Aging; Animals; Biomechanical

1984
Beta-adrenergic regulation of rat parotid gland exocrine protein secretion during aging.
    Mechanisms of ageing and development, 1981, Volume: 15, Issue:2

    Topics: Aging; Amylases; Animals; Dihydroalprenolol; Dose-Response Relationship, Drug; In Vitro Techniques;

1981
[Ultrastructure and metabolic heterogeneity of cardiomyocytes in acute myocardial injury during aging].
    Biulleten' eksperimental'noi biologii i meditsiny, 1982, Volume: 94, Issue:10

    Topics: Aging; Animals; Autoradiography; Cardiomyopathies; Histocytochemistry; Isoproterenol; Male; Microsco

1982
Secretion of alpha-amylase from parotid lobules of young and old rats.
    Experimental gerontology, 1982, Volume: 17, Issue:5

    Topics: Aging; Amylases; Animals; Isoproterenol; Male; Microscopy, Electron; Parotid Gland; Propranolol; Rat

1982
Effect of clenbuterol, a new beta 2 selective adrenoceptor stimulant, on the release of histamine and SRS-A from passively sensitized guinea-pig chopped lungs.
    General pharmacology, 1984, Volume: 15, Issue:4

    Topics: Aging; Albuterol; Animals; Chromones; Clenbuterol; Ethanolamines; Guinea Pigs; Histamine Release; In

1984
Effect of aging and cellularity on lipolysis in isolated mouse fat cells.
    Journal of lipid research, 1980, Volume: 21, Issue:1

    Topics: Adipose Tissue; Adrenocorticotropic Hormone; Aging; Animals; Body Weight; Bucladesine; Epididymis; G

1980
Dual mechanism for inhibition of calcium-dependent action potentials by acetylcholine in avian ventricular muscle. Relationship to cyclic AMP.
    Circulation research, 1980, Volume: 46, Issue:3

    Topics: Acetylcholine; Action Potentials; Aging; Animals; Calcium; Catecholamines; Chick Embryo; Cyclic AMP;

1980
Dietary manipulation of age-related decline in vascular smooth muscle function.
    The American journal of physiology, 1980, Volume: 238, Issue:5

    Topics: Aging; Animals; Aorta; Food Deprivation; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Va

1980
Age and beta adrenoceptor-mediated function.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aging; Binding Sites; Cyclic AMP; Dose-Response Relationship,

1980
Plasma catecholamines and cardiac, renal and peripheral vascular adrenoceptor-mediated responses in different age groups of normal and hypertensive subjects.
    Clinical and experimental hypertension, 1980, Volume: 2, Issue:3-4

    Topics: Adult; Aging; Epinephrine; Heart Rate; Humans; Hypertension; Isoproterenol; Kidney; Middle Aged; Nor

1980
Ontogenetic development of isoproterenol subsensitivity of myocardial adenylate cyclase and beta-adrenergic receptors in spontaneously hypertensive rats.
    Biochimica et biophysica acta, 1980, Nov-03, Volume: 632, Issue:4

    Topics: Adenylyl Cyclases; Aging; Animals; Body Weight; Cell Membrane; Dihydroalprenolol; Heart; Hypertensio

1980
Regulation of protein kinase inhibitor by follicle-stimulating hormone in Sertoli cells in vitro.
    Endocrinology, 1981, Volume: 108, Issue:2

    Topics: Aging; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Follicle

1981
Age-related elevation of plasma catecholamine concentration and reduced responsiveness of lymphocyte adenylate cyclase.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 52, Issue:5

    Topics: Adenylyl Cyclases; Adult; Aging; Cyclic AMP; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Lymph

1981
Human lymphocyte beta-adrenergic receptors are unaltered with age.
    Journal of gerontology, 1981, Volume: 36, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Dihydroalprenolol; Epinephrine; Female; Humans; Isoproterenol; Lymph

1981
The effect of aging on beta-adrenoceptor-stimulated cyclic AMP formation in human lymphocytes.
    Clinical science (London, England : 1979), 1981, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Cyclic AMP; Female; Humans; Isoproterenol; Lymphocytes; Male; Stimul

1981
Age-associated decrease of adenylate cyclase activity in rat myocardium.
    Mechanisms of ageing and development, 1981, Volume: 16, Issue:1

    Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Female; Guanosine Triphosphat

1981
Quantitative analysis of the lipid-mobilizing effects of corticotropin, beta 1-24--corticotropin (tetracosactide) and isoprenaline in older rats and rabbits.
    Physiologia Bohemoslovaca, 1981, Volume: 30, Issue:3

    Topics: Adipose Tissue; Adrenocorticotropic Hormone; Aging; Animals; Cosyntropin; Dose-Response Relationship

1981
The development of pre- and postsynaptic components of the noradrenergic system in the rat cerebellum.
    Journal of neurochemistry, 1981, Volume: 37, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Brain; Cerebellum; Dihydroalprenolol; Female; Isoproterenol; Kine

1981
Isoproterenol responsiveness and myocardial beta-adrenergic receptors in young and old rats.
    Journal of gerontology, 1982, Volume: 37, Issue:2

    Topics: Aging; Animals; Dihydroalprenolol; Female; Heart Rate; Isoproterenol; Lung; Lymphocytes; Myocardium;

1982
Age-related decrease of in vitro isoproterenol-induced cyclic AMP accumulation in rat aorta.
    European journal of pharmacology, 1982, Jan-22, Volume: 77, Issue:2-3

    Topics: Aging; Animals; Aorta, Thoracic; Arteries; Cyclic AMP; DNA; Isoproterenol; Male; Muscle Relaxation;

1982
Maturation-related changes in catecholamine-dependent cyclic AMP and protein kinase in the rabbit myocardium.
    Developmental pharmacology and therapeutics, 1981, Volume: 3, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Catecholamines; Cyclic AMP; Isoproterenol; Myocardium; Phentolami

1981
Responsiveness of the trimmed rat subcutaneous adipose tissue beta-receptors to catecholamines in ontogenesis.
    Physiologia Bohemoslovaca, 1982, Volume: 31, Issue:1

    Topics: Adipose Tissue; Aging; Animals; Catecholamines; Epinephrine; Fatty Acids, Nonesterified; Female; In

1982
Beta-receptors during aging in respiratory tissues.
    European journal of pharmacology, 1982, Feb-19, Volume: 78, Issue:1

    Topics: Aging; Animals; Benzyl Alcohols; Bronchi; Female; Guinea Pigs; Histamine; Isoproterenol; Muscle Rela

1982
Adenylate cyclase and beta adrenergic receptor development in the mouse heart.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 222, Issue:1

    Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Dihydroalprenolol; Female; Fetal Heart; Heart;

1982
Comparison of the effects of age and phorbol myristate acetate on the beta-adrenergic system in mouse epidermis.
    Mechanisms of ageing and development, 1982, Volume: 18, Issue:3

    Topics: Aging; Animals; Cyclic AMP; Epidermis; Female; Isoproterenol; Mice; Mice, Inbred ICR; Phorbols; Tetr

1982
Decreased beta-adrenergic agonist affinity and adenylate cyclase activity in senescent rat lung.
    Journal of gerontology, 1983, Volume: 38, Issue:2

    Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Colforsin; Dihydroalprenolol; Diterpenes; F

1983
Ageing as a factor governing the effect of isoproterenol on the cyclic AMP level in isolated aorta from spontaneously hypertensive and normotensive rats.
    European journal of pharmacology, 1983, Jan-21, Volume: 86, Issue:3-4

    Topics: Aging; Animals; Aorta; Cyclic AMP; DNA; Hypertension; In Vitro Techniques; Isoproterenol; Male; Rats

1983
Age-related changes in the control of hepatic cyclic AMP levels by alpha 1- and beta 2-adrenergic receptors in male rats.
    The Journal of biological chemistry, 1983, Apr-25, Volume: 258, Issue:8

    Topics: Aging; Animals; Cyclic AMP; Epinephrine; Isoproterenol; Liver; Male; Prazosin; Propranolol; Rats; Ra

1983
Decreased neutrophil cyclic AMP response to isoprenaline stimulation in the elderly.
    Clinical science (London, England : 1979), 1983, Volume: 65, Issue:2

    Topics: Adult; Aged; Aging; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Isoproterenol; Neutrophils

1983
Lymphocyte adenylate cyclase and human aging.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1983, Volume: 173, Issue:4

    Topics: Adenylyl Cyclases; Adult; Aged; Aging; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism;

1983
Beta-adrenergic control of phosphatidylcholine synthesis by transmethylation in hepatocytes from juvenile, adult and adrenalectomized rats.
    The Biochemical journal, 1983, Dec-15, Volume: 216, Issue:3

    Topics: Adrenalectomy; Aging; Animals; Cyclic AMP; Ethanolamines; In Vitro Techniques; Insulin; Isoprotereno

1983
Beta-1 and beta-2 adrenoceptor-mediated responses in preparations of pulmonary artery and aorta from young and aged rats.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:3

    Topics: Aging; Animals; Aorta; Cocaine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Tec

1984
[Effect of drugs on cyclic AMP levels in the tissues of animals at different stages of ontogenesis. I. Experimental studies on the effect of adrenomimetic drugs on cyclic AMP concentration in the brain of 7-day-old and adult rats].
    Problemy medycyny wieku rozwojowego, 1983, Volume: 12

    Topics: Aging; Animals; Blood-Brain Barrier; Brain; Cyclic AMP; Female; Isoproterenol; Male; Norepinephrine;

1983
Intercellular communication in rat seminiferous tubules.
    Developmental biology, 1983, Volume: 100, Issue:1

    Topics: Aging; Animals; Calcimycin; Cell Communication; Electrophysiology; Freeze Fracturing; Isoproterenol;

1983
Effects of timed melatonin infusions on reproductive development in the Djungarian hamster (Phodopus sungorus).
    Endocrinology, 1984, Volume: 114, Issue:6

    Topics: Aging; Animals; Cricetinae; Follicle Stimulating Hormone; Infusions, Parenteral; Isoproterenol; Male

1984
Adenylate cyclase activity in crude plasma membranes of subcutaneous adipocytes during ontogenetic development of rats.
    Physiologia Bohemoslovaca, 1982, Volume: 31, Issue:1

    Topics: Adenylyl Cyclases; Adipose Tissue; Aging; Animals; Cell Membrane; Cosyntropin; Female; Guanosine Tri

1982
Ontogenetic studies on adrenergic lipolysis in rat adipocytes from subcutaneous adipose tissue.
    Physiologia Bohemoslovaca, 1982, Volume: 31, Issue:1

    Topics: Adipose Tissue; Aging; Animals; Cell Count; Epinephrine; Fatty Acids, Nonesterified; Female; In Vitr

1982
Noradrenergic influences on blocking: interactions with development.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:1

    Topics: Aging; Animals; Attention; Avoidance Learning; Conditioning, Operant; Female; Growth; Isoproterenol;

1984
Effect of age on adrenergic neuronal uptake in rat heart.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:2

    Topics: Aging; Analysis of Variance; Animals; Catecholamines; Cocaine; Heart Rate; Isoproterenol; Male; Myoc

1984
Age-related changes in sensitivity of rat urinary bladder to autonomic agents.
    Mechanisms of ageing and development, 1984, Oct-15, Volume: 27, Issue:2

    Topics: Acetylcholine; Aging; Animals; Autonomic Agents; In Vitro Techniques; Isoproterenol; Male; Muscle Co

1984
Effects of age on the adrenergic cardiac neuroeffector junction.
    Life sciences, 1984, Dec-24, Volume: 35, Issue:26

    Topics: Aging; Animals; Cardiac Output; Dogs; Epinephrine; Heart; Heart Rate; Humans; Isoproterenol; Nerve E

1984
Depletion of myocardial potassium as a function of age and experimental necrosis.
    Indian journal of experimental biology, 1984, Volume: 22, Issue:3

    Topics: Aging; Animals; Female; Isoproterenol; Myocardial Infarction; Myocardium; Necrosis; Potassium; Rats;

1984
Secretory protein synthesis in parotid glands of young and old rats.
    Archives of oral biology, 1983, Volume: 28, Issue:1

    Topics: Aging; alpha-Amylases; Animals; Electrophoresis, Polyacrylamide Gel; Isoproterenol; Male; Parotid Gl

1983
Influence of motor activity on the development of isoprenaline induced heart lesions.
    Physiologia Bohemoslovaca, 1983, Volume: 32, Issue:3

    Topics: Aging; Animals; Body Weight; Heart Diseases; Isoproterenol; Male; Motor Activity; Rats; Rats, Inbred

1983
Age-dependent changes in electrophysiologic characteristics of fast and slow action potentials in rat papillary muscle.
    Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:12

    Topics: Action Potentials; Aging; Animals; Dose-Response Relationship, Drug; Electrophysiology; In Vitro Tec

1983
Age-dependent alterations in the formation of cyclic nucleotides caused by various agents in guinea-pig tracheal smooth muscle.
    The Tokushima journal of experimental medicine, 1983, Volume: 30, Issue:3-4

    Topics: Aging; Animals; Animals, Newborn; Carbachol; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male;

1983
Higher sensitivity of cerebral arteries isolated from premature and newborn baboons to adrenergic and cholinergic stimulation.
    Life sciences, 1984, Jul-16, Volume: 35, Issue:3

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Cerebral Arteries; Female; Gestational Age; In Vitr

1984
[Perifusion study of the secretion of calcitonin in the young rat: effect of isoproterenol and theophylline].
    Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 1981, Jan-19, Volume: 292, Issue:3

    Topics: Aging; Animals; Calcitonin; Isoproterenol; Rats; Theophylline; Thyroid Gland

1981
Growth, food intake, motor activity and experimental cardiac necrosis in early malnourished male rats.
    Annals of nutrition & metabolism, 1982, Volume: 26, Issue:2

    Topics: Aging; Animals; Cardiomyopathies; Diet; Growth; Isoproterenol; Male; Motor Activity; Myocardium; Nec

1982
Circulatory effects of chemical sympathectomy in fetal, neonatal, and adult sheep.
    The American journal of physiology, 1982, Volume: 243, Issue:1

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Blood Pressure; Cardiovascular Physiological Phenom

1982
Catalytic unit of adenylate cyclase: reduced activity in aged-human lymphocytes.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 55, Issue:5

    Topics: Adenylyl Cyclases; Adult; Aged; Aging; Colforsin; Diterpenes; Enzyme Activation; Guanosine Triphosph

1982
Non-developmental modifications induced in submandibular glands of young rats by chronic isoproterenol administration.
    Archives of oral biology, 1981, Volume: 26, Issue:4

    Topics: Aging; Animals; Electrophoresis; Isoproterenol; Male; Rats; Salivary Proteins and Peptides; Submandi

1981
Age-related decrease in cardiac and peripheral vascular responsiveness to isoprenaline: studies in normal subjects.
    Clinical science (London, England : 1979), 1981, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Blood Pressure; Epinephrine; Female; Forearm; Heart Rate; Humans; Is

1981
Comparative response of the developing canine myocardium to inotropic agents.
    The American journal of physiology, 1982, Volume: 242, Issue:1

    Topics: Aging; Animals; Calcium; Dogs; Heart; Isoproterenol; Myocardial Contraction; Ventricular Function

1982
The comparative hemodynamic effects of propranolol in chronically instrumented puppies and adult dogs.
    Biology of the neonate, 1982, Volume: 41, Issue:1-2

    Topics: Aging; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Isoproterenol; Kidne

1982
Age-related changes in pineal "synaptic" ribbon populations in rats exposed to continuous light or darkness.
    The American journal of anatomy, 1982, Volume: 163, Issue:2

    Topics: Aging; Animals; Darkness; Female; Isoproterenol; Light; Pineal Gland; Propranolol; Rats; Time Factor

1982
Changes in the synthesis of exportable and nonexportable proteins in parotid glands during aging.
    Mechanisms of ageing and development, 1982, Volume: 18, Issue:3

    Topics: Aging; Animals; Electrophoresis, Polyacrylamide Gel; Isoproterenol; Male; Parotid Gland; Protein Bio

1982
Functional significance of reduced cardiac sympathetic innervation in the newborn dog.
    The American journal of physiology, 1982, Volume: 243, Issue:1

    Topics: Adrenalectomy; Aging; Animals; Animals, Newborn; Dogs; Heart; Heart Conduction System; Heart Rate; H

1982
The influences of glucagon, epinephrine and adrenergic agents on glycogen phosphorylase a and pyruvate kinase activities in hepatocytes from juvenile and adult rabbits.
    Biochimica et biophysica acta, 1982, Jul-16, Volume: 717, Issue:1

    Topics: Aging; Animals; Epinephrine; Glucagon; Isoproterenol; Liver; Male; Phentolamine; Phenylephrine; Phos

1982
[The effect of adrenaline and isoprenaline on calcium level in the plasma of rats of various ages].
    Sbornik lekarsky, 1982, Volume: 84, Issue:7

    Topics: Aging; Animals; Calcium; Epinephrine; Female; Isoproterenol; Male; Rats; Rats, Inbred Strains

1982
The postnatal development of adrenoceptor responses in isolated papillary muscles from rat.
    Pflugers Archiv : European journal of physiology, 1980, Volume: 383, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Norepinep

1980
Secretin and VIP-stimulated adenylate cyclase from rat heart. II. Impairment in spontaneous hypertension.
    Pflugers Archiv : European journal of physiology, 1980, Volume: 389, Issue:1

    Topics: Adenylyl Cyclases; Aging; Animals; Brain; Enzyme Activation; Gastrointestinal Hormones; Glucagon; Hy

1980
Morphological response of blood platelets to increased venular permeability in vivo.
    Microvascular research, 1981, Volume: 21, Issue:1

    Topics: Aging; Animals; Blood Platelets; Cell Membrane Permeability; Eye; Isoproterenol; Male; Rats; Time Fa

1981
Age-dependent changes in the myocardial adenylate cyclase of normotensive and spontaneously hypertensive rat.
    Pharmacology, 1981, Volume: 22, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Body Weight; Hypertension; Isoproterenol; Male; Microsomes; Muscl

1981
Role of aortic input impedance in the decreased cardiovascular response to exercise with aging in dogs.
    The Journal of clinical investigation, 1981, Volume: 68, Issue:1

    Topics: Aging; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dogs; Electric Conductiv

1981
The effect of calcium on the inotropy of catecholamine and paired electrical stimulation in the newborn and adult myocardium.
    Journal of molecular and cellular cardiology, 1981, Volume: 13, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; H

1981
Adenylate cyclase activity in the uterine cervix of neonatal and immature mice: influence of oestradiol-17 beta.
    The Journal of endocrinology, 1980, Volume: 84, Issue:2

    Topics: Adenylyl Cyclases; Aging; Animals; Cervix Uteri; DNA; Estradiol; Female; Guanylyl Imidodiphosphate;

1980
Effect of beta adrenergic agents on blood vessels of the rat iris. I. Permeability to carbon particles.
    Experimental eye research, 1980, Volume: 31, Issue:3

    Topics: Aging; Aminophylline; Animals; Capillary Permeability; Carbon; Iris; Isoproterenol; Male; Propanolam

1980
Effect of beta adrenergic agents on blood vessels of the rat iris. II. Morphological modifications of the vessel wall.
    Experimental eye research, 1980, Volume: 31, Issue:3

    Topics: Aging; Animals; Capillary Permeability; Carbon; Endothelium; Iris; Isoproterenol; Male; Microscopy,

1980
Response and sensitivity of female guinea-pig respiratory tissues to agonists during ontogenesis.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 215, Issue:2

    Topics: Age Factors; Aging; Albuterol; Animals; Female; Guinea Pigs; Histamine; In Vitro Techniques; Indomet

1980
Comparison of the inotropic action of digitalis and isoproterenol in younger and older individuals.
    American heart journal, 1980, Volume: 100, Issue:6 Pt 1

    Topics: Adolescent; Adult; Aged; Aging; Digitalis Glycosides; Electrocardiography; Female; Humans; Isoproter

1980
[Stress/strain ratio of the left ventricle in systole. Influence of age and of some drugs (author's transl)].
    Giornale italiano di cardiologia, 1980, Volume: 10, Issue:5

    Topics: Adult; Aged; Aging; Echocardiography; Electrocardiography; Female; Health; Heart; Heart Ventricles;

1980
The comparative hemodynamic effects of isoproterenol in chronically instrumented puppies and adult dogs.
    Developmental pharmacology and therapeutics, 1981, Volume: 2, Issue:2

    Topics: Aging; Animals; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Hemodynamics; Isoproterenol; Regio

1981
Decreased contractile responses to isoproterenol in isolated cardiac myocytes from aging guinea-pigs.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:5

    Topics: Adrenergic beta-Agonists; Aging; Animals; Calcium; Dose-Response Relationship, Drug; Guinea Pigs; He

1995
Age-dependent changes in response of rat prostatic tissues to isoproterenol and forskolin: changes with sexual maturation in function of G proteins.
    Mechanisms of ageing and development, 1995, Jun-30, Volume: 81, Issue:1

    Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Cell Nucl

1995
Developmental changes in modulation of calcium currents of rabbit ventricular cells by phosphodiesterase inhibitors.
    Circulation, 1994, Volume: 90, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Animals, Newborn; Calcium; Dose-Response Relationship,

1994
Developmental changes in modulation of contractility of rabbit hearts.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Blood Pressure; Co

1995
G protein alterations in hypertension and aging.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:5

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Adult; Aging; Aluminum Compoun

1995
Age-related changes in the noradrenergic pattern and receptor responses of the rat cardiovascular system after repeated microwave exposure.
    The International journal of neuroscience, 1995, Volume: 82, Issue:1-2

    Topics: Aging; Animals; Cardiovascular System; Histocytochemistry; Isoproterenol; Male; Microwaves; Norepine

1995
Effect of ageing and propranolol administration on myocardial beta-adrenoceptor receptor function in mature rats.
    European journal of pharmacology, 1995, Apr-28, Volume: 289, Issue:2

    Topics: Age Factors; Aging; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Heart; Isoproterenol; Mal

1995
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured;

1993
Effect of aging and drug-induced weight reduction on rat vascular reactivity.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:1

    Topics: Administration, Oral; Aging; Animals; Aorta; Blood Glucose; Body Weight; Endothelium, Vascular; Fenf

1993
Head-up tilt testing with and without isoproterenol infusion in healthy subjects of different ages.
    Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:4 Pt 1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Carotid Sinus; Catecholamines; Electrocardiog

1993
Age-dependent alterations in beta-adrenergic responsiveness of rat detrusor smooth muscle.
    The Journal of urology, 1995, Volume: 153, Issue:5

    Topics: Aging; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Electric Stimulation; Isoproteren

1995
Vasomotor reactivity and catecholamine, arginine vasopressin plasma levels during ageing and development in rats.
    Mechanisms of ageing and development, 1994, Nov-25, Volume: 77, Issue:1

    Topics: Acetylcholine; Aging; Animals; Arginine; Arterial Occlusive Diseases; Blood Pressure; Carotid Artery

1994
The role of adenosine in promoting cardiac beta-adrenergic subsensitivity in aging humans.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50, Issue:3

    Topics: Adenosine; Adult; Aged; Aging; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate;

1995
The effects of chronic treatment with N-tert-butyl-alpha-phenylnitrone on cerebellar noradrenergic receptor function in aged F344 rats.
    Brain research, 1994, Oct-17, Volume: 660, Issue:2

    Topics: Aging; Animals; Cerebellum; Cyclic N-Oxides; gamma-Aminobutyric Acid; Isoproterenol; Male; Membrane

1994
Influence of age and gender on skin vessel reactivity to endothelium-dependent and endothelium-independent vasodilators tested with iontophoresis and a laser Doppler perfusion imager.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50, Issue:2

    Topics: Acetylcholine; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anesthetics, Local; Endothelium, V

1995
Norepinephrine and posttraining memory consolidation in neonatal rats.
    Behavioral neuroscience, 1994, Volume: 108, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Appetitive Behavior; Association Learning; Brain; Conditioning, Cl

1994
Beta-adrenergic effects on left ventricular filling: influence of aging and exercise training.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:6

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Coronary Circulation; D

1994
Expression of beta 1- and beta 3-adrenergic-receptor messages and adenylate cyclase beta-adrenergic response in bovine perirenal adipose tissue during its transformation from brown into white fat.
    The Biochemical journal, 1994, Jan-01, Volume: 297 ( Pt 1)

    Topics: Adenylyl Cyclases; Adipose Tissue; Adipose Tissue, Brown; Adrenergic beta-Agonists; Aging; Amino Aci

1994
Age-related changes in DNA synthesis stimulated by epinephrine and isoproterenol in primary cultured rat hepatocytes.
    Journal of cellular physiology, 1994, Volume: 158, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aging; Animals; Cells, Cultured; DNA; Epi

1994
Atypical beta-adrenergic receptors in rat liver: evidence for transient expression during aging.
    Journal of gerontology, 1994, Volume: 49, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Isoproterenol; Liver; Male; Propanol

1994
Beta-adrenergic regulation of action potentials and automaticity in young and adult canine purkinje fibers.
    The American journal of physiology, 1994, Volume: 266, Issue:6 Pt 2

    Topics: Action Potentials; Adrenergic beta-Antagonists; Aging; Albuterol; Animals; Cardiac Pacing, Artificia

1994
Age-related changes in the response of the rat urinary bladder to neurotransmitters.
    Neurourology and urodynamics, 1993, Volume: 12, Issue:2

    Topics: Aging; Animals; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; Neur

1993
Noradrenergic innervation and receptor responses of cardiovascular tissues from young and aged rats after acute microwave exposure.
    The International journal of neuroscience, 1994, Volume: 76, Issue:3-4

    Topics: Aging; Animals; Aorta, Abdominal; Cardiovascular System; Dose-Response Relationship, Radiation; Envi

1994
Electrophysiological basis for the enhanced cardiac arrhythmogenic effect of isoprenaline in aged spontaneously hypertensive rats.
    Journal of molecular and cellular cardiology, 1994, Volume: 26, Issue:7

    Topics: Action Potentials; Aging; Animals; Arrhythmias, Cardiac; Hypertension; In Vitro Techniques; Isoprote

1994
Influence of exercise training on myocardial beta-adrenergic signal transduction: differential regulation with age.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:2

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Female; GTP-Binding Proteins; Heart

1994
Effects of aging on responses to isoproterenol tilt-table testing in patients with syncope.
    The American journal of cardiology, 1994, Sep-01, Volume: 74, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Child; Female; Hemodynamics; Humans; Isoprotereno

1994
The effect of age on the beta-adrenergic lipolytic response in healthy humans.
    Clinical pharmacology and therapeutics, 1994, Volume: 56, Issue:2

    Topics: Adult; Aged; Aging; Blood Glucose; Blood Pressure; Catecholamines; Fatty Acids; Female; Glycerol; He

1994
Effect of age on beta-receptors, Gs alpha- and Gi alpha- proteins in rat heart.
    Biochemical pharmacology, 1994, Aug-03, Volume: 48, Issue:3

    Topics: Adenylyl Cyclases; Aging; Amino Acid Sequence; Animals; Body Weight; GTP-Binding Proteins; Heart Ven

1994
Norepinephrine-induced relaxations in rat aorta mediated by endothelial beta adrenoceptors. Impairment by ageing and hypertension.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2

    Topics: Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isoproter

1994
Relationship between cAMP production and protein secretion in rat submandibular acini: evidence for loss of reserve capacity with age.
    Life sciences, 1994, Volume: 55, Issue:10

    Topics: Aging; Animals; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Isopro

1994
Age-related changes in beta-adrenergic neuroeffector systems in the human heart.
    Circulation, 1994, Volume: 90, Issue:3

    Topics: Adenylyl Cyclases; Adolescent; Adult; Aging; Binding, Competitive; Child; Child, Preschool; Denervat

1994
Developmental appearance of pineal adrenergic-->guanosine 3',5'-monophosphate response is determined by a process down-stream from elevation of intracellular Ca2+: possible involvement of a diffusible factor.
    Endocrinology, 1993, Volume: 132, Issue:3

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenal Glands; Aging; Animals; Arachidonic Acid; Calcium; Cell

1993
Alpha-2 adrenergic receptor activity in porcine adipocytes is androgen and age/cell size dependent.
    Comparative biochemistry and physiology. Comparative physiology, 1993, Volume: 105, Issue:2

    Topics: Adipose Tissue; Aging; Androgens; Animals; Cell Size; Epinephrine; Isoproterenol; Lipolysis; Male; P

1993
Are there any differences in the excitation-contraction coupling of the working myocardium of adult and newborn guinea-pigs?
    Physiological research, 1993, Volume: 42, Issue:5

    Topics: Action Potentials; Aging; Animals; Animals, Newborn; Caffeine; Calcium; Electrophysiology; Guinea Pi

1993
Secretion of ions and pharmacological responsiveness in the mouse paw sweat gland.
    Clinical science (London, England : 1979), 1994, Volume: 86, Issue:2

    Topics: Aging; Animals; Colforsin; Culture Techniques; Cyclic AMP; Eccrine Glands; Forelimb; Isoproterenol;

1994
Maturation of catecholamine response and extraneuronal uptake in rabbit trachea.
    The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 1

    Topics: Aging; Animals; Animals, Newborn; Catecholamines; In Vitro Techniques; Isoproterenol; Neurons; Norep

1994
Impaired beta-adrenergic receptor-mediated regulation of gene expression in adipocytes from older rats.
    The American journal of physiology, 1994, Volume: 266, Issue:4 Pt 1

    Topics: Adenosine Deaminase; Adipocytes; Aging; Animals; Animals, Newborn; Base Sequence; Gene Expression Re

1994
Age-dependent changes in the phosphorylation of nuclear proteins of submandibular glands in isoproterenol-treated rats.
    Mechanisms of ageing and development, 1993, Aug-01, Volume: 70, Issue:1-2

    Topics: Aging; Animals; DNA; Isoproterenol; Male; Nuclear Proteins; Phosphorylation; Protein Kinases; Rats;

1993
Adrenoceptor coupling mechanisms which regulate salivary secretion during aging.
    Life sciences, 1993, Volume: 53, Issue:25

    Topics: Aging; Animals; Cell Membrane; Cyclic AMP; In Vitro Techniques; Inositol Phosphates; Isoproterenol;

1993
Desipramine desensitizes beta-adrenergic signal transduction in salivary glands: differential regulation with age.
    European journal of pharmacology, 1993, Sep-15, Volume: 247, Issue:1

    Topics: Adenylyl Cyclases; Aging; Analysis of Variance; Animals; Cerebral Cortex; Desipramine; Down-Regulati

1993
Regulation of capillary exchange capacity in postnatal swine intestine.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1

    Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Blood Pressure; Capillaries; Hemodynamics; H

1993
Postnatal decrease in muscarinic cholinergic influence on Ca2+ currents of rabbit ventricular cells.
    The American journal of physiology, 1993, Volume: 264, Issue:6 Pt 2

    Topics: Adenylate Cyclase Toxin; Aging; Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Carbac

1993
Age-related alterations in the phosphorylation of sarcoplasmic reticulum and myofibrillar proteins and diminished contractile response to isoproterenol in intact rat ventricle.
    Circulation research, 1993, Volume: 72, Issue:1

    Topics: Aging; Animals; Isoproterenol; Male; Myocardial Contraction; Myofibrils; Phosphorylation; Rats; Rats

1993
The effects of ethanol on gamma-aminobutyric acid-induced depressions of cerebellar Purkinje neurons: influence of beta adrenergic receptor action in young and aged Fischer 344 rats.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Aging; Animals; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Isoproterenol; Male; Purkinje Cell

1993
Effects of exercise on myocardial adenylate cyclase and Gi alpha expression in senescence.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 2

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Aging; Amino Acid Sequence; Animals; Cell Membrane; Cycl

1993
Diminished cardiac contractile response to burn injury in aged guinea pigs.
    The Journal of trauma, 1993, Volume: 34, Issue:3

    Topics: Aging; Animals; Burns; Calcium Channels; Depression, Chemical; Diltiazem; Guinea Pigs; Isoproterenol

1993
Motor learning deficits in aged rats are correlated with loss of cerebellar noradrenergic function.
    Brain research, 1993, Aug-20, Volume: 620, Issue:1

    Topics: Aging; Animals; Cerebellum; Drug Synergism; Electrophysiology; gamma-Aminobutyric Acid; Isoprotereno

1993
Cardiac contractile and calcium transport function after burn injury in adult and aged guinea pigs.
    The Journal of surgical research, 1993, Volume: 55, Issue:1

    Topics: Aging; Animals; Biological Transport; Blood Pressure; Burns; Calcium; Electric Stimulation; Guinea P

1993
Ontogeny of rat myocardial A1 adenosine receptors.
    Biology of the neonate, 1995, Volume: 68, Issue:2

    Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Binding, Competitive; Cells, Cultured; C

1995
Adenosine attenuation of isoproterenol-stimulated adenylyl cyclase activity is enhanced with aging in the adult heart.
    Life sciences, 1996, Volume: 58, Issue:6

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals;

1996
Role of muscarinic M2 receptors in regulating beta-adrenergic responsiveness in maturing rabbit airway smooth muscle.
    The American journal of physiology, 1995, Volume: 269, Issue:6 Pt 1

    Topics: Aging; Animals; Diamines; Dose-Response Relationship, Drug; Gallamine Triethiodide; GTP-Binding Prot

1995
A role of asialoglycoproteins for plasma-membrane-induced inhibition of the switching from alpha 1 to beta subtypes in adrenergic response during primary culture of rat hepatocytes.
    The Biochemical journal, 1996, Jun-15, Volume: 316 ( Pt 3)

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; As

1996
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-09, Volume: 93, Issue:14

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Cell Membr

1996
Adenosine and carbachol are not equivalent in their effects on L-type calcium current in rabbit ventricular cells.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:2

    Topics: Adenosine; Aging; Amino Acid Sequence; Animals; Animals, Newborn; Calcium Channels; Carbachol; Colfo

1996
Myocardial adenosine A1 and A2 receptor activities during juvenile and adult stages of development.
    The American journal of physiology, 1996, Volume: 271, Issue:1 Pt 2

    Topics: Adenosine; Aging; Animals; Coronary Vessels; Drug Synergism; Heart; Isoproterenol; Male; Myocardial

1996
Lymphocyte norepinephrine and epinephrine, but not plasma catecholamines predict lymphocyte cAMP production.
    Life sciences, 1996, Volume: 59, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Adult; Aged; Aged, 80 and over; Aging; Cyclic AMP; Epinephrine; Humans;

1996
Beta-adrenergic modulation of Na-K pump activity in young and adult canine cardiac Purkinje fibers.
    The American journal of physiology, 1996, Volume: 271, Issue:2 Pt 2

    Topics: Adrenergic beta-Agonists; Aging; Animals; Dogs; Electrophysiology; Isoproterenol; Models, Biological

1996
Occurrence and properties of the hyperpolarization-activated current If in ventricular myocytes from normotensive and hypertensive rats during aging.
    Circulation, 1996, Oct-01, Volume: 94, Issue:7

    Topics: Aging; Animals; Cardiomegaly; Electric Conductivity; Electrophysiology; Hypertension; Isoproterenol;

1996
Atypical regulation of hepatic adenylyl cyclase and adrenergic receptors during a critical developmental period: agonists evoke supersensitivity accompanied by failure of receptor down-regulation.
    Pediatric research, 1996, Volume: 39, Issue:4 Pt 1

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Down-Regulation; Female; Heart; Isoprot

1996
Beta-adrenoceptor function changes with age of subject in myocytes from non-failing human ventricle.
    Cardiovascular research, 1996, Volume: 31, Issue:1

    Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Calcium; Cell Size; Cells, Cultured; Child; Coronary D

1996
Age-related differences in beta-adrenergic regulation of repolarization in canine epicardial myocytes.
    The American journal of physiology, 1996, Volume: 271, Issue:3 Pt 2

    Topics: Action Potentials; Adrenergic beta-Agonists; Aging; Animals; Calcium; Dogs; Electric Conductivity; I

1996
cAMP signaling mechanisms with aging in rats.
    Mechanisms of ageing and development, 1996, Jan-05, Volume: 86, Issue:1

    Topics: Aging; Animals; Aorta; Blotting, Western; Catalysis; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase

1996
The effects of aging on cerebellar beta-adrenergic receptor activation and motor learning in female F344 rats.
    Neuroscience letters, 1996, Sep-20, Volume: 216, Issue:1

    Topics: Action Potentials; Adrenergic beta-Agonists; Aging; Animals; Cerebellum; Female; gamma-Aminobutyric

1996
Exercise training improves lusitropy by isoproterenol in papillary muscles from aged rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1996, Volume: 81, Issue:4

    Topics: Adrenergic beta-Agonists; Aging; Animals; Calcium; Heart; In Vitro Techniques; Isometric Contraction

1996
Ontogeny of beta-adrenergic desensitization in rabbit tracheal smooth muscle.
    Pediatric pulmonology, 1996, Volume: 22, Issue:4

    Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Dinoprostone; Dose-Response Relationship

1996
P48: a novel nuclear protein possibly associated with aging and mortality.
    Aging (Milan, Italy), 1996, Volume: 8, Issue:5

    Topics: Aging; Animals; Bone Marrow Cells; Cell Nucleus; Electrophoresis, Gel, Two-Dimensional; Electrophore

1996
Beta-adrenoceptor control of cardiac adenylyl cyclase during development: agonist pretreatment in the neonate uniquely causes heterologous sensitization, not desensitization.
    Brain research, 1995, Oct-02, Volume: 694, Issue:1-2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Female; Fluorides; GT

1995
Differences in isoproterenol stimulation of Ca2+ current of rat ventricular myocytes in neonatal compared to adult.
    European journal of pharmacology, 1996, Dec-19, Volume: 317, Issue:2-3

    Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Calcium Channel Agonists; Calcium Channe

1996
Properties and modulation of If in newborn versus adult cardiac SA node.
    The American journal of physiology, 1997, Volume: 272, Issue:3 Pt 2

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Cells, Cultured; Diastole; Heart Rate; Isoprotereno

1997
Thermoregulation with age: role of beta-adrenergic signal transduction.
    Annals of the New York Academy of Sciences, 1997, Mar-15, Volume: 813

    Topics: Adipose Tissue, Brown; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Body T

1997
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents;

1997
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents;

1997
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents;

1997
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents;

1997
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents;

1997
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents;

1997
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents;

1997
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents;

1997
Volume history effects and airway responsiveness in middle-aged and older men. The Normative Aging Study.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:3

    Topics: Aged; Aging; Bronchi; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents;

1997
Desensitization of alpha 1-, beta- and glucagon receptors in rat hepatocytes: influence of ageing.
    Mechanisms of ageing and development, 1994, Volume: 75, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Centrifugation, Density Gradien

1994
Effect of donor age on porcine insulin secretion.
    Transplantation proceedings, 1997, Volume: 29, Issue:4

    Topics: Aging; Animals; Carbachol; Cells, Cultured; Glucose; Insulin; Insulin Secretion; Islets of Langerhan

1997
Expression of adenylyl cyclase mRNAs in the adult, in developing, and in the Brattleboro rat kidney.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Arginine Vasopressin; Calcium; Cell Membrane; C

1997
Impairment of vasodilator function in basilar arteries from aged rats.
    Stroke, 1997, Volume: 28, Issue:9

    Topics: Adrenergic beta-Agonists; Aging; Animals; Basilar Artery; Bradykinin; Dose-Response Relationship, Dr

1997
Light-induced changes in frog pineal gland N-acetyltransferase activity.
    Neurochemistry international, 1997, Volume: 31, Issue:4

    Topics: Aging; Animals; Arylamine N-Acetyltransferase; Darkness; Eye Enucleation; Isoproterenol; Light; Ligh

1997
Effects of adenosine and isoprenaline in left atria from both neonatal and middle-aged noninsulin-dependent diabetic rat models.
    General pharmacology, 1997, Volume: 29, Issue:4

    Topics: Adenosine; Aging; Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Diabete

1997
Beta-adrenergic regulation of constitutive nitric oxide synthase in cardiac myocytes.
    The American journal of physiology, 1997, Volume: 273, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifl

1997
Aging and fluid homeostasis in rats.
    The American journal of physiology, 1997, Volume: 273, Issue:4

    Topics: Aging; Angiotensins; Animals; Appetite; Avoidance Learning; Body Fluids; Diuresis; Drinking; Female;

1997
Effect of long-term food restriction on cardiac mechanics.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Aging; Analysis of Variance; Animals; Body Weight; Calcium; Energy Intake; Heart; In Vitro Technique

1997
Myocardial action potential prolongation by calcium channel activation under calcium free-EGTA conditions in guinea-pigs: developmental and regional variations.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 97, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Action Potentials; Adrenergic b

1997
Differential adrenergic regulation of rat pineal cyclic AMP production and N-acetyltransferase activity during postnatal development: involvement of G alpha s and G alpha i1-2 proteins.
    The Journal of endocrinology, 1997, Volume: 155, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; An

1997
Cardiac muscarinic receptors decrease with age. In vitro and in vivo studies.
    The Journal of clinical investigation, 1998, Jan-15, Volume: 101, Issue:2

    Topics: Acetylcholine; Adenylyl Cyclases; Adult; Aged; Aging; Child; Dose-Response Relationship, Drug; Heart

1998
Beta-adrenergic-mediated improvement in left ventricular function by exercise training in older men.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Aging; Blood

1998
Myocardial adenosine A1-receptor sensitivity during juvenile and adult stages of maturation.
    The American journal of physiology, 1998, Volume: 274, Issue:2

    Topics: Adenosine; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Heart; Heart Rate; Isoproter

1998
Reduced DNA synthesis in primary cultures of hepatocytes from old mice is restored by thymus grafts.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1998, Volume: 53, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Animals, Newborn; Blood Physi

1998
Effect of aging on beta-adrenergically mediated thermogenesis in men.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Adipose Tissue; Adrenergic beta-Agonists; Adult; Aged; Aging; Basal Metabolism; Body Composition; Bo

1998
Involvement of IsK-associated K+ channel in heart rate control of repolarization in a murine engineered model of Jervell and Lange-Nielsen syndrome.
    Circulation research, 1998, Jul-13, Volume: 83, Issue:1

    Topics: Aging; Animals; Blotting, Northern; Cardiotonic Agents; Cells, Cultured; Disease Models, Animal; Ele

1998
Effect of age on in vitro magnesium modulation of vascular reactivity in the rat aorta.
    Magnesium research, 1998, Volume: 11, Issue:2

    Topics: Acetylcholine; Aging; Animals; Aorta; Calcium Chloride; Dose-Response Relationship, Drug; Endotheliu

1998
Food restriction alters the age-related decline in cardiac beta-adrenergic responsiveness.
    Mechanisms of ageing and development, 1998, Jun-01, Volume: 103, Issue:1

    Topics: Adrenergic beta-Agonists; Aging; Animals; Food Deprivation; Heart; In Vitro Techniques; Isoprotereno

1998
Glucocorticoid-targeting of the adenylyl cyclase signaling pathway in the cerebellum of young vs. aged rats.
    Brain research, 1998, Aug-03, Volume: 800, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Anti-Inflammatory Agents; Cerebellum; C

1998
Pharmacological and molecular characterisation of beta-adrenoceptors in adult rat diaphragm muscle.
    Respiration physiology, 1998, Volume: 112, Issue:1

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Dose-Respo

1998
Control of arterial tone after long-term coenzyme Q10 supplementation in senescent rats.
    British journal of pharmacology, 1998, Volume: 124, Issue:7

    Topics: Acetylcholine; Aging; Animals; Coenzymes; Isoproterenol; Male; Mesenteric Arteries; Muscle Contracti

1998
The myocardial beta-adrenergic system in spontaneously hypertensive heart failure (SHHF) rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Aging; Animals; beta-Adrenergic Receptor Kinases; Cyclic AMP-Dependent Protein Kinases; Disease Mode

1999
Influence of chronic ethanol consumption on arterial tone in young and aged rats.
    The American journal of physiology, 1999, Volume: 276, Issue:2

    Topics: Acetylcholine; Aging; Alcohol Drinking; Animals; Cromakalim; In Vitro Techniques; Isoproterenol; Mal

1999
Lack of an effect of age on beta-adrenoceptor-mediated lipolysis in isolated human adipocytes.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1999, Volume: 54, Issue:2

    Topics: Adipocytes; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; A

1999
Characterisation of the function of adult guinea-pig ventricular myocytes following co-culture with neonatal rat myocytes.
    Basic research in cardiology, 1999, Volume: 94, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Calcium; Cardiotonic Agents; Cells, Cultured; Coculture Techniques

1999
[The involvement of muscarinic M1 receptor in the regulation of action potentials in mouse isolated right atria].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1998, Volume: 112 Suppl 1

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Action Potentia

1998
Effects of age on outcome of tilt-table testing.
    The American journal of cardiology, 1999, Apr-01, Volume: 83, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Child; Female; Heart Rate; Humans

1999
Impaired cholera toxin relaxation with age in rat aorta.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1999, Volume: 54, Issue:4

    Topics: Adenosine Diphosphate; Adrenergic beta-Agonists; Aging; Animals; Aorta, Thoracic; Cholera Toxin; Col

1999
Impaired isoproterenol-induced hyperpolarization in isolated mesenteric arteries of aged rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Age Factors; Aging; Animal

1999
Regulation of myocardial beta-adrenergic receptor function in adult and neonatal rabbits.
    Biology of the neonate, 1999, Volume: 76, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; GTP-Binding Proteins;

1999
The influence of animal age on beta-adrenoceptor density and function in tracheal airway smooth muscle.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:2

    Topics: Adrenergic beta-Agonists; Aging; Animals; Autoradiography; Catechol O-Methyltransferase; Cricetinae;

1999
Beta-adrenergically stimulated fat oxidation is diminished in middle-aged compared to young subjects.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:10

    Topics: Adrenergic beta-Agonists; Adult; Aging; Carbohydrate Metabolism; Dose-Response Relationship, Drug; E

1999
Impaired lusitropy-frequency in the aging mouse: role of Ca(2+)-handling proteins and effects of isoproterenol.
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Adrenergic beta-Agonists; Aging; Animals; Blood Pressure; Calcium-Binding Proteins; Calcium-Transpor

1999
Effects of age and gender on the cardiovascular responses to isoproterenol.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1999, Volume: 54, Issue:9

    Topics: Adrenergic beta-Agonists; Aging; Cardiovascular System; Humans; Isoproterenol; Receptors, Adrenergic

1999
Left ventricular response to beta-adrenergic stimulation in aging rats.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2000, Volume: 55, Issue:1

    Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Aging; Analysis of Variance; Animals; Atrial Na

2000
Negative inotropic effects of isoprenaline on isolated left atrial assays from aged transgenic mice with cardiac over-expression of human beta(2)-adrenoceptors.
    British journal of pharmacology, 2000, Volume: 129, Issue:7

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta

2000
Functional and morphological modifications of the urinary bladder in aging female rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:4

    Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Arecoli

2000
Effects of cyclopentyladenosine on isoproterenol response in adult and senescent cardiac tissue from Fischer 344 rats.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals;

2000
Ontogeny of G-protein expression: control by beta-adrenoceptors.
    Brain research. Developmental brain research, 2000, Apr-14, Volume: 120, Issue:2

    Topics: Adrenergic beta-Agonists; Aging; Animals; Colforsin; Drug Tolerance; Female; Fluorides; Gene Express

2000
Age-related involvement of the endothelium in beta-adrenoceptor-mediated relaxation of rat aorta.
    European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Aorta, Thoracic; Apamin; Aten

2000
Alterations in G-proteins and beta-adrenergic responsive adenylyl cyclase in rat urinary bladder during aging.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists;

2000
Adolescent nicotine exposure alters cardiac autonomic responsiveness: beta-adrenergic and m2-muscarinic receptors and their linkage to adenylyl cyclase.
    Brain research, 2000, Sep-29, Volume: 878, Issue:1-2

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Autonomic Nervous Sys

2000
Angiotensin II enhances beta-adrenergic receptor-mediated vasorelaxation in aortas from young but not old rats.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Angiotensin II; Animals; Aorta, Thorac

2000
Adaptations in beta-adrenergic cardiovascular responses to training in older women.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 89, Issue:6

    Topics: Adaptation, Physiological; Adrenergic beta-Agonists; Aged; Aging; Atropine; Blood Pressure; Cardiova

2000
Age-related differences in messenger ribonucleic acid expression of key proteins involved in adipose cell differentiation and metabolism.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:2

    Topics: Abdomen; Adipocytes; Adipose Tissue; Adult; Aging; Bucladesine; Canada; Cell Differentiation; Colfor

2001
Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality.
    Circulation, 2001, Feb-13, Volume: 103, Issue:6

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Calcium-Binding Proteins; Cardiomyop

2001
Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:10

    Topics: Adrenergic beta-Agonists; Age Factors; Aging; Animals; Arginine; Blotting, Western; Citrulline; Cycl

2001
No loss in the in vivo efficacy of ischemic preconditioning in middle-aged and old rabbits.
    Journal of the American College of Cardiology, 2001, Nov-15, Volume: 38, Issue:6

    Topics: Aging; Analysis of Variance; Animals; Cardiotonic Agents; Hemodynamics; Ischemic Preconditioning, My

2001
Impaired cardiac contractility response to hemodynamic stress in S100A1-deficient mice.
    Molecular and cellular biology, 2002, Volume: 22, Issue:8

    Topics: Adrenergic beta-Agonists; Aging; Animals; Calcium Signaling; Calcium-Binding Proteins; Gene Targetin

2002
Effects of different inotropic interventions on myocardial function in the developing rabbit heart.
    Basic research in cardiology, 2002, Volume: 97, Issue:1

    Topics: Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Azetidines; Calcium; Calcium-Transportin

2002
Adrenergic-cholinergic interaction that modulates repolarization in the atrium is altered with aging.
    Journal of cardiovascular electrophysiology, 2002, Volume: 13, Issue:4

    Topics: Acetylcholine; Action Potentials; Adrenergic beta-Agonists; Aging; Animals; Dogs; Dose-Response Rela

2002
Biochemical and morphological effects of testosterone treatment on developing sympathetic neurons.
    Journal of neurochemistry, 1978, Volume: 30, Issue:6

    Topics: Aging; Animals; Cell Count; Ganglia, Autonomic; Isoproterenol; Neurons; Rats; Submandibular Gland; T

1978
A comparative study of pineal acetyl-CoA hydrolase and N-acetyltransferase activities.
    Journal of neurochemistry, 1979, Volume: 32, Issue:1

    Topics: Acetyl-CoA Hydrolase; Acetyltransferases; Aging; Animals; Animals, Newborn; Circadian Rhythm; Female

1979
Alpha- and beta-adrenergic mechanisms in the aorta of newborn rabbits and guinea-pigs.
    General pharmacology, 1979, Volume: 10, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aging; Animals; Animals, Newborn; Aorta; Female

1979
Maturation- and species-related differences in inotropic response to isoproterenol.
    Comparative biochemistry and physiology. C: Comparative pharmacology, 1979, Volume: 63C, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Guinea Pigs; Isoproterenol; Myocardial Contraction; Rabbits; Speci

1979
Alterations in the cardiovascular system that occur in advanced age.
    Federation proceedings, 1979, Volume: 38, Issue:2

    Topics: Adult; Aged; Aging; Blood Pressure; Cardiomegaly; Cardiovascular Physiological Phenomena; Chemorecep

1979
Effects of 6-hydroxydopamine Treatment at birth on the submaxillary gland of the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 289, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Autonomic Fibers, Postganglionic; Choline O-Acetyltransferase; Coc

1975
Biochemical aspects of cardiac muscle differentiation. Possible control of deoxyribonucleic acid synthesis and cell differentiation by adrenergic innervation and cyclic adenosine 3':5'-monophosphate.
    The Journal of biological chemistry, 1976, Oct-10, Volume: 251, Issue:19

    Topics: Aging; Animals; Animals, Newborn; Bucladesine; Cell Differentiation; Cyclic AMP; Cyclic GMP; DNA Rep

1976
Vascular adenylate cyclase: role of age and guanine nucleotide activation.
    Blood vessels, 1977, Volume: 14, Issue:1

    Topics: Adenosine; Adenylyl Cyclases; Aging; Animals; Aorta; Cyclic AMP; Guanine Nucleotides; Guanosine Trip

1977
Age-related parallel decline in beta-adrenergic receptors, adenylate cyclase and phosphodiesterase activity in rat erythrocyte membranes.
    Life sciences, 1977, Aug-01, Volume: 21, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Aging; Alprenolol; Animals; Benzyl Alcohols;

1977
Regulation of antigen induced changes in cyclic nucleotide levels in NZB/wf1 mice.
    Cellular immunology, 1978, Mar-15, Volume: 36, Issue:2

    Topics: Aging; Animals; Antigens; Antilymphocyte Serum; Complement System Proteins; Cyclic AMP; Dose-Respons

1978
Development of secretory function in rat parotid gland.
    Pediatric research, 1978, Volume: 12, Issue:2

    Topics: Aging; Amylases; Animals; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Parotid Gland

1978
beta-Adrenergic receptors and catecholamine-sensitive adenylate cyclase in rat fat-cell membranes: influence of growth, cell size and aging.
    European journal of biochemistry, 1978, Volume: 90, Issue:2

    Topics: Adenylyl Cyclases; Adipose Tissue; Aging; Animals; Binding, Competitive; Isoproterenol; Kinetics; Ma

1978
Vascular relaxation, aging and thyroid hormones.
    Mechanisms of ageing and development, 1978, Volume: 8, Issue:6

    Topics: Aging; Animals; Aorta; Blood Vessels; Dose-Response Relationship, Drug; Female; Hypophysectomy; Isop

1978
Effect of intra-amnial administration of a cardiotoxic dose of isoproterenol on cyclic AMP levels in the chick embryo heart.
    Journal of molecular and cellular cardiology, 1979, Volume: 11, Issue:11

    Topics: Aging; Amnion; Animals; Chick Embryo; Cyclic AMP; Heart; Injections; Isoproterenol; Myocardium

1979
Age related changes in hormone binding by target cells and tissues; possible role in altered adaptive responsiveness.
    Experimental gerontology, 1975, Volume: 10, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Aging; Animals; Aorta; Child; Female; Glucocor

1975
Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the pre-weanling rat.
    British journal of pharmacology, 1979, Volume: 65, Issue:3

    Topics: Aging; Animals; Atropine; Chlorisondamine; Electrocardiography; Female; Heart Rate; Isoproterenol; M

1979
Age-associated decrease in heart rate response to isoproterenol in dogs.
    Mechanisms of ageing and development, 1979, Volume: 10, Issue:1-2

    Topics: Aging; Anesthesia; Animals; Atropine; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Is

1979
Adrenergic control of glycolysis and pyruvate kinase activity in hepatocytes from young and old rats.
    The Journal of biological chemistry, 1979, Aug-25, Volume: 254, Issue:16

    Topics: Aging; Animals; Epinephrine; Glucagon; Glucose; Glycolysis; In Vitro Techniques; Isoproterenol; Lact

1979
Renal circulatory effects of adrenergic stimuli in anesthetized piglets and mature swine.
    The American journal of physiology, 1979, Volume: 237, Issue:6

    Topics: Aging; Animals; Electric Stimulation; Isoproterenol; Kidney; Norepinephrine; Regional Blood Flow; Sw

1979
Morphological and functional study of the effect of isoproterenol on salivary gland cells.
    Cell and tissue research, 1979, Volume: 203, Issue:2

    Topics: Aging; Animals; Cytoplasmic Granules; Isoproterenol; Protein Biosynthesis; Rats; Submandibular Gland

1979
Postnatal development of adrenergic and cholinergic sensitivity in the isolated rat atria.
    Experientia, 1977, Dec-15, Volume: 33, Issue:12

    Topics: Acetylcholine; Aging; Animals; Carbachol; Heart; Heart Atria; Isoproterenol; Male; Norepinephrine; P

1977
Isoprenaline relaxation in vascular smooth muscle of aged rats. Effect of flunarizine.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 230, Issue:2

    Topics: Aging; Animals; Blood Vessels; Drug Interactions; In Vitro Techniques; Isoproterenol; Muscle Contrac

1977
Advanced age as a factor in the response of rodents to drugs [proceedings].
    Advances in experimental medicine and biology, 1978, Volume: 97

    Topics: Aging; Animals; Cricetinae; Female; Hexobarbital; Hydralazine; Isoproterenol; Male; Mesocricetus; Mi

1978
Cardiac output changes during neonatal growth.
    The American journal of physiology, 1978, Volume: 234, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Atropine; Cardiac Output; Female; Heart Rate; Isoproterenol; Propr

1978
The postnatal development of adrenoceptor responses to agonists and electrical stimulation in rat isolated atria.
    British journal of pharmacology, 1978, Volume: 64, Issue:1

    Topics: Aging; Animals; Electric Stimulation; Female; Heart; Heart Rate; In Vitro Techniques; Isoproterenol;

1978
Influence of ageing on the isoprenaline relaxation of aortae from normal and hypertensive rats.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 236, Issue:2

    Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; In Vitro Techniques; Isoproterenol; M

1978
Alternative mechanisms for the potentiation of the relaxation evoked by isoprenaline in aortae from young and aged rats.
    European journal of pharmacology, 1979, Jan-15, Volume: 53, Issue:3

    Topics: Aging; Animals; Aorta, Thoracic; Blood Vessels; Cinnarizine; Drug Synergism; Isoproterenol; Muscle C

1979
The relationship between age and relaxation of vascular smooth muscle in the rabbit and rat.
    Circulation research, 1976, Volume: 38, Issue:4

    Topics: Aging; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; Isoproterenol; Male; Musc

1976
Sensitivity of the developing chick myocardium to the positive inotropic effects of calcium and isoproterenol.
    Experientia, 1977, Jan-15, Volume: 33, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Calcium; Chick Embryo; Chickens; Heart; In Vitro Techniques; Isopr

1977
Age-related changes in course of restitution of secretory material in rat submandibular gland stimulated with isoproterenol.
    Experimental gerontology, 1977, Volume: 12, Issue:3-4

    Topics: Aging; Animals; Histocytochemistry; Isoproterenol; Leucine; Male; Rats; Submandibular Gland

1977
Concentration of sialic acids in submandibular glands of young and old rats treated with isoproterenol.
    Experimental gerontology, 1976, Volume: 11, Issue:5-6

    Topics: Aging; Animals; Isoproterenol; Male; Rats; Sialic Acids; Submandibular Gland; Time Factors

1976
Effect of aging on regeneration of glandular secretion in rat salivaries.
    Folia morphologica, 1976, Volume: 35, Issue:4

    Topics: Aging; Animals; Isoproterenol; Male; Rats; Regeneration; Salivary Glands; Secretory Rate

1976
Diminished inotropic response of aged myocardium to catecholamines.
    Circulation research, 1975, Volume: 36, Issue:2

    Topics: Aging; Animals; Calcium; Heart; Heart Rate; Isoproterenol; Male; Norepinephrine; Rats

1975
[Dependence on age of the effects of catecholamines in man I. Effect of noradrenaline, adrenaline and isoprenaline on blood pressure and heart rate].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1975, Feb-01, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Aging; Blood Pressure; Child, Preschool; Epinephrine; Female;

1975
Studies of aqueous humor dynamics in man. V. Effects of acetazolamide and isoproterenol in young and old normal volunteers.
    Investigative ophthalmology, 1976, Volume: 15, Issue:5

    Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aging; Aqueous Humor; Fem

1976
Drop in the "atypical" beta-adrenergic response and modification of the beta/alpha 2-adrenoceptor balance in fat cells from aging rabbits.
    Endocrinology, 1992, Volume: 130, Issue:1

    Topics: Adipose Tissue; Adrenocorticotropic Hormone; Aging; Animals; Brimonidine Tartrate; Epinephrine; Etha

1992
Influence of animal age on the beta-adrenergic system in cultured rat aortic and mesenteric artery smooth muscle cells.
    Journal of gerontology, 1992, Volume: 47, Issue:2

    Topics: Aging; Alprostadil; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response

1992
The effect of donor age on human fibroblast beta-adrenergic receptor response and agonist-induced desensitization.
    Mechanisms of ageing and development, 1992, Volume: 62, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Cyclic AMP; Drug Resistance; Fibroblasts; Humans; In Vitro Te

1992
Beta-adrenergic responsiveness in cultured aorta smooth muscle cells. Effects of subculture and aging.
    Biochemical pharmacology, 1992, Apr-15, Volume: 43, Issue:8

    Topics: Adenylyl Cyclases; Aging; Animals; Aorta, Thoracic; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme A

1992
Age and beta-adrenergic receptor sensitivity to S(-)- and R,S(+/-)-propranolol in humans.
    Clinical pharmacology and therapeutics, 1992, Volume: 51, Issue:5

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Blood Pressure; Heart Rate; Humans; Isoprotereno

1992
Age-related alterations of isoproterenol-stimulated adenylyl-cyclase activity are partially corrected by thymic graft.
    Annals of the New York Academy of Sciences, 1992, Apr-15, Volume: 650

    Topics: Adenylyl Cyclases; Aging; Animals; Enzyme Activation; Isoproterenol; Mice; Mice, Inbred BALB C; Mice

1992
The effect of in vitro aging on human lung fibroblast beta-adrenergic receptor density, coupling and response.
    Mechanisms of ageing and development, 1992, Volume: 63, Issue:3

    Topics: Adenylyl Cyclases; Aging; Alprostadil; Cell Line; Cellular Senescence; Fibroblasts; Guanosine Tripho

1992
Isolated ventricular myocytes from failing and non-failing human heart; the relation of age and clinical status of patients to isoproterenol response.
    Journal of molecular and cellular cardiology, 1992, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Calcium; Cardiotonic Agents; Child; Female; Heart; Heart Failure; Hu

1992
Relationship between potency of L-isoprenaline and beta-adrenoceptor density estimated in single cells from tracheal smooth muscles of guinea pigs of different ages.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:4

    Topics: Aging; Animals; Binding, Competitive; Dihydroalprenolol; Guinea Pigs; In Vitro Techniques; Isoproter

1992
Influence of exercise and age on myocardial beta-adrenergic receptor properties.
    Experimental gerontology, 1992, Volume: 27, Issue:2

    Topics: Aging; Analysis of Variance; Animals; Binding, Competitive; Female; Heart Rate; Iodocyanopindolol; I

1992
Vascular beta-adrenoceptor-mediated responses in hypertension and ageing in rats.
    Journal of autonomic pharmacology, 1992, Volume: 12, Issue:6

    Topics: Aging; Animals; Aorta, Thoracic; Blood Pressure; Hypertension; Isoproterenol; Male; Muscle Contracti

1992
Reduced contractile responses to forskolin and a cyclic AMP analogue in myocytes from failing human ventricle.
    European journal of pharmacology, 1992, Nov-13, Volume: 223, Issue:1

    Topics: Adult; Aging; Bucladesine; Calcium; Colforsin; Diuretics; Female; Heart Failure; Heart Ventricles; H

1992
Beta-adrenergic receptors and salivary gland secretion during aging.
    Growth, development, and aging : GDA, 1992,Winter, Volume: 56, Issue:4

    Topics: Aging; Animals; Dose-Response Relationship, Drug; Female; Iodocyanopindolol; Isoproterenol; Pilocarp

1992
Somatostatin and growth hormone-releasing factor release from Zucker rat hypothalamic tissue.
    Brain research bulletin, 1992, Volume: 29, Issue:6

    Topics: Aging; Animals; Growth Hormone-Releasing Hormone; Hypothalamus, Middle; In Vitro Techniques; Iodine

1992
A biochemical analysis of parotid and submandibular salivary gland function with age after simultaneous stimulation with pilocarpine and isoproterenol in female NIA Fischer 344 rats.
    Archives of oral biology, 1992, Volume: 37, Issue:3

    Topics: Aging; alpha-Amylases; Animals; DNA; Epidermal Growth Factor; Female; Isoproterenol; Parotid Gland;

1992
Amylase mRNA synthesis and ageing in rat parotid glands following isoproterenol-stimulated secretion.
    Archives of oral biology, 1992, Volume: 37, Issue:5

    Topics: Aging; Amylases; Animals; Antisense Elements (Genetics); Blotting, Northern; Immunoblotting; Isoprot

1992
Post-train administration of 9-amino-1,2,3,4-tetrahydroacridine enhances passive avoidance retention and decreases beta-adrenoceptor-linked cyclic AMP formation in middle-aged rats.
    Brain research, 1992, Jul-17, Volume: 586, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Avoidance Learning; Cerebral Cortex; Conditioning, Psyc

1992
Aging: inotropic effects of Bay K-8644 and nifedipine on rat cardiac muscle.
    European journal of pharmacology, 1992, Jun-17, Volume: 216, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
[Response of the cardiovascular system in elderly patients to intravenous infusion of isoproterenol and adrenaline].
    Przeglad lekarski, 1992, Volume: 49, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aging; Blood Pressure; Dose-Response Relationship, Drug; Epine

1992
Bradykinin-induced venodilation is not impaired with aging in humans.
    Journal of gerontology, 1992, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Bradykinin; Dose-Response Relationship, Drug; Fem

1992
The association of E. coli peritonitis with an impaired and delayed fever response in senescent rats.
    Journal of gerontology, 1992, Volume: 47, Issue:4

    Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Aging; Animals; Escherichia coli Infections; Female; Fever

1992
Effects of subacute exposure to noise on the noradrenergic innervation of the cardiovascular system in young and aged rats: a morphofunctional study.
    Journal of neural transmission. General section, 1992, Volume: 88, Issue:2

    Topics: Aging; Animals; Aorta; Atrial Function; Cardiovascular Physiological Phenomena; Cardiovascular Syste

1992
Differences in cardiovascular responses to isoproterenol in relation to age and exercise training in healthy men.
    Circulation, 1992, Volume: 86, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Hemodynamics; Humans; Isoproterenol; Male; Middle Aged; Oxyge

1992
Nuclear estradiol binding in rat adipocytes. Regional variations and regulatory influences of hormones.
    Biochimica et biophysica acta, 1991, Jun-07, Volume: 1093, Issue:1

    Topics: Adipose Tissue; Aging; Animals; Bucladesine; Cell Nucleus; Estradiol; Insulin; Isoproterenol; Kineti

1991
Beta-adrenergic responsiveness in cultured vascular smooth muscle cells and fibroblasts: effect of age.
    Mechanisms of ageing and development, 1991, Volume: 57, Issue:3

    Topics: Aging; Analysis of Variance; Animals; Aorta; Cells, Cultured; Colforsin; Cyclic AMP; Fibroblasts; Is

1991
Beta-adrenergic regulation of insulin secretion: evidence of tissue heterogeneity of beta-adrenergic responsiveness in the elderly.
    Journal of gerontology, 1991, Volume: 46, Issue:4

    Topics: Adult; Aged; Aging; Blood Glucose; Cyclic AMP; Epinephrine; Female; Heart Rate; Humans; Insulin; Ins

1991
Regional differences in adrenoreceptor status of adipose tissue in adults and prepubertal children.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 73, Issue:2

    Topics: Adipose Tissue; Adult; Aging; Analysis of Variance; Child; Female; Humans; In Vitro Techniques; Isop

1991
Beta-adrenergic signal transduction in aging parotid and submandibular salivary glands.
    Journal of gerontology, 1991, Volume: 46, Issue:6

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; F

1991
Ontogeny of beta-adrenergic receptor-mediated cyclic AMP generating system in primary cultured neurons.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1991, Volume: 9, Issue:4

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Aging; Animals; Brain; Cell Division; Cells, Cultured; C

1991
Cardiac beta-adrenoceptor sensitivity and Parkinson's disease.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:6

    Topics: Aged; Aging; Blood Pressure; Bromocriptine; Dose-Response Relationship, Drug; Female; Heart Rate; Hu

1991
Effects of aging and drugs on myocardial beta-adrenergic receptors in M-SHRSP and SHRSP.
    Clinical and experimental hypertension. Part A, Theory and practice, 1991, Volume: 13, Issue:5

    Topics: 5'-Nucleotidase; Aging; Animals; Cardiomegaly; Cerebrovascular Disorders; Disease Susceptibility; Do

1991
Multiple adrenergic receptor subtypes controlling cyclic AMP formation: comparison of brain slices and primary neuronal and glial cultures.
    Journal of neurochemistry, 1991, Volume: 56, Issue:2

    Topics: Adrenergic alpha-Agonists; Aging; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Colfo

1991
Beta-adrenergic receptor activity of cerebral microvessels is reduced in aged rats.
    Neurochemical research, 1991, Volume: 16, Issue:4

    Topics: Adenylyl Cyclases; Aging; Alkaline Phosphatase; Animals; Brain; Cerebrovascular Circulation; gamma-G

1991
Differences in the accessibility of the beta-adrenergic receptor in isolated hepatocytes from foetal and adult rats.
    Cellular signalling, 1991, Volume: 3, Issue:4

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Female; Glucose; Isoproterenol; Live

1991
Subsensitivity to beta-adrenoceptor agonists in pacemakers isolated from senescent rats.
    General pharmacology, 1991, Volume: 22, Issue:5

    Topics: Adrenergic beta-Agonists; Aging; Animals; Cocaine; Ethanolamines; Heart; Heart Rate; In Vitro Techni

1991
Beta-adrenoceptor responsiveness in intact leukocytes from adults and newborn infants; effect of phosphodiesterase inhibitors.
    Scandinavian journal of clinical and laboratory investigation, 1990, Volume: 50, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Aging; Cyclic AMP; Humans;

1990
Ontogeny of the adenylate cyclase system in the pulmonary vascular smooth muscle of the fetal lamb.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:1

    Topics: Adenylyl Cyclases; Aging; Animals; Cell Membrane; Colforsin; Cyclic AMP; Embryonic and Fetal Develop

1991
Decreased beta-adrenoceptor-mediated vasodilation in aorta from aged rats: possible involvement of a stimulatory GTP-binding protein.
    European journal of pharmacology, 1991, Jun-06, Volume: 198, Issue:2-3

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Aging; Animals; Aorta; Clenbuterol; Colforsin; Cycli

1991
Use-dependent decline in rat aorta sensitivity to contraction by potassium.
    Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1991
Acute effects of tetrahydroaminoacridine on beta-adrenoceptor-linked cyclic AMP accumulation in brain of young and middle-aged rats.
    Neuroscience letters, 1991, Oct-28, Volume: 132, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Brain; Cerebral Cortex; Cholinesterase Inhibitors; Cycl

1991
Beta adrenergically mediated cardiac chronotropic and vascular smooth muscle responses during propranolol therapy and withdrawal in young and elderly persons.
    Journal of gerontology, 1992, Volume: 47, Issue:1

    Topics: Adult; Aged; Aging; Blood Pressure; Female; Heart Rate; Humans; Isoproterenol; Male; Muscle, Smooth,

1992
Effects of physiological aging on cardiac electrophysiology in perfused Fischer 344 rat hearts.
    The American journal of physiology, 1992, Volume: 262, Issue:1 Pt 2

    Topics: Aging; Animals; Atrioventricular Node; Bundle of His; Dose-Response Relationship, Drug; Electrophysi

1992
Age-related impairment of signal transduction and its correction with antioxidants.
    Annals of the New York Academy of Sciences, 1991, Volume: 640

    Topics: Adenylyl Cyclases; Aging; Animals; Brain; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-;

1991
Increased mucin levels in submandibular glands of aged male mice after chronic isoproterenol treatment.
    Archives of oral biology, 1991, Volume: 36, Issue:7

    Topics: Aging; Analysis of Variance; Animals; Circadian Rhythm; Female; Injections, Intraperitoneal; Isoprot

1991
Agonist-induced Ca2+ mobilization in the rat submandibular gland during aging and subsequent to chronic propranolol treatment.
    Mechanisms of ageing and development, 1991, Nov-15, Volume: 61, Issue:1

    Topics: Aging; Animals; Calcium; Carbachol; Female; In Vitro Techniques; Intracellular Fluid; Isoproterenol;

1991
Waning cardiovascular responses to adrenergic drugs in conscious ageing rats.
    Mechanisms of ageing and development, 1991, Dec-31, Volume: 61, Issue:3

    Topics: Aging; Angiotensin II; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascul

1991
Ontogeny of responses of rabbit aorta to atrial natriuretic factor and isoproterenol.
    Developmental pharmacology and therapeutics, 1991, Volume: 16, Issue:2

    Topics: Aging; Animals; Atrial Natriuretic Factor; Drug Interactions; Isoproterenol; Muscle Contraction; Mus

1991
Ontogeny of renal renin release in spontaneously hypertensive rat and Wistar-Kyoto rat.
    The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 2

    Topics: Aging; Angiotensin II; Animals; Hypertension; Isoproterenol; Kidney Cortex; Kidney Tubules, Proximal

1991
Left ventricular responses to experimental aortic coarctation in growing puppies.
    Acta physiologica Scandinavica, 1991, Volume: 141, Issue:3

    Topics: Aging; Animals; Aortic Coarctation; Blood Pressure; Collateral Circulation; Dogs; Heart Ventricles;

1991
[Effects of cernitin pollen extract (CN-009) on the isolated bladder smooth muscles and the intravesical pressure].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 97, Issue:5

    Topics: Aging; Animals; Atropine; Cats; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Drug

1991
Norepinephrine and isoproterenol increase the phosphorylation of synapsin I and synapsin II in dentate slices of young but not aged Fisher 344 rats.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Mar-15, Volume: 88, Issue:6

    Topics: Aging; Animals; Cytoskeletal Proteins; Hippocampus; In Vitro Techniques; Isoproterenol; Kinetics; Mi

1991
Isoproterenol activation of prostaglandin production in guinea-pig airway muscle preparations from immature and mature animals.
    Prostaglandins, 1991, Volume: 41, Issue:3

    Topics: Aging; Animals; Bronchi; Dinoprost; Dinoprostone; Enzyme Activation; Guinea Pigs; Histamine; Isoprot

1991
Dose-dependent effect of prenatal dexamethasone treatment on beta-adrenergic receptor coupling to ornithine decarboxylase and cyclic AMP.
    Journal of developmental physiology, 1990, Volume: 14, Issue:3

    Topics: Aging; Analysis of Variance; Animals; Body Weight; Cyclic AMP; Dexamethasone; Dose-Response Relation

1990
Regulation of postnatal beta-adrenergic receptor/adenylate cyclase development by prenatal agonist stimulation and steroids: alterations in rat kidney and lung after exposure to terbutaline or dexamethasone.
    Journal of developmental physiology, 1990, Volume: 14, Issue:5

    Topics: Adenylyl Cyclases; Aging; Analysis of Variance; Animals; Binding Sites; Body Weight; Colforsin; Dexa

1990
Ontogeny of renal beta adrenoceptors in the sheep.
    Pediatric nephrology (Berlin, Germany), 1990, Volume: 4, Issue:6

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Binding, Competitive; Ethanol

1990
Age-related changes in responses to nerve stimulation and catecholamines in isolated monkey cerebral arteries.
    The American journal of physiology, 1991, Volume: 260, Issue:5 Pt 2

    Topics: Aging; Animals; Cerebral Arteries; Electric Stimulation; Female; In Vitro Techniques; Isoproterenol;

1991
Cardiotoxicity of hydralazine and minoxidil in the rat. Influence of age.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 71, Issue:2

    Topics: Aging; Animals; Blood Pressure; Heart Diseases; Heart Rate; Hydralazine; Isoproterenol; Minoxidil; M

1991
Age-associated differences in beta adrenergic-stimulated lipolysis in adipocytes from Sprague-Dawley and Fischer 344 rats.
    Journal of gerontology, 1991, Volume: 46, Issue:4

    Topics: Adipose Tissue; Aging; Animals; Body Weight; Glycerol; In Vitro Techniques; Isoproterenol; Lipolysis

1991
[Changes of three types in the secretory systems present in the rat submandibular glands during aging].
    Fukuoka Shika Daigaku Gakkai zasshi, 1990, Volume: 17, Issue:2

    Topics: Aging; Animals; Clonidine; Isoproterenol; Male; Norepinephrine; Rats; Receptors, Adrenergic; Saliva;

1990
Age-related changes in relaxant response of vascular smooth muscles to atrial natriuretic peptide.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:3

    Topics: Acetylcholine; Aging; Animals; Aorta; Atrial Natriuretic Factor; Body Weight; Dose-Response Relation

1990
The beta-adrenergic transduction system in kidneys from young and senescent rats.
    European journal of pharmacology, 1990, Mar-13, Volume: 188, Issue:2-3

    Topics: Adenylyl Cyclase Inhibitors; Aging; Animals; Cyclic AMP; Guanylyl Imidodiphosphate; In Vitro Techniq

1990
Age-dependent alterations in beta-adrenergic receptor function in guinea pig ureter.
    Progress in clinical and biological research, 1990, Volume: 327

    Topics: Aging; Animals; Cyclic AMP; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Isoproterenol; M

1990
Developmental changes in beta-adrenergic and cholinergic interactions on calcium-dependent slow action potentials in rat ventricular muscles.
    British journal of pharmacology, 1990, Volume: 99, Issue:2

    Topics: Acetylcholine; Action Potentials; Aging; Animals; Calcium; Female; Heart; Heart Ventricles; In Vitro

1990
Catecholamine-induced lipolysis in adipose tissue of the elderly.
    The Journal of clinical investigation, 1990, Volume: 85, Issue:5

    Topics: Adipose Tissue; Adult; Age Factors; Aged; Aging; Cells, Cultured; Humans; Isoproterenol; Kinetics; L

1990
Age-related deficit in beta receptor stimulation of cAMP binding in blood vessels.
    Mechanisms of ageing and development, 1990, Apr-09, Volume: 53, Issue:2

    Topics: Aging; Animals; Aorta, Thoracic; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Kinetics

1990
Role of beta-adrenoceptor-adenylate cyclase system in the developmental decrease in sensitivity to isoprenaline in foetal and neonatal rat heart.
    British journal of pharmacology, 1990, Volume: 100, Issue:1

    Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Colforsin; Dihydroalprenolol; Enzyme Activation

1990
Effect of aging on the response of guinea pig trachea to isoprenaline.
    Japanese journal of pharmacology, 1990, Volume: 53, Issue:3

    Topics: Aging; Animals; Corticosterone; Dihydroalprenolol; Guinea Pigs; In Vitro Techniques; Isoproterenol;

1990
Age-related differences in cyclic AMP metabolism and their consequences on relaxation induced by isoproterenol and phosphodiesterase inhibitors in rat isolated aorta.
    Mechanisms of ageing and development, 1990, Volume: 54, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Aorta, Thoracic; Cyclic AMP; Isoproterenol; Male; Muscle Relaxati

1990
Prenatal nicotine exposure impairs beta-adrenergic function: persistent chronotropic subsensitivity despite recovery from deficits in receptor binding.
    Brain research bulletin, 1990, Volume: 25, Issue:2

    Topics: Aging; Animals; Body Weight; Female; Heart; Heart Rate; Isoproterenol; Maternal-Fetal Exchange; Nico

1990
Effects of age and adenosine in the modulation of insulin action on rat adipocyte metabolism.
    Journal of gerontology, 1990, Volume: 45, Issue:5

    Topics: Adenosine; Adipose Tissue; Aging; Animals; Dose-Response Relationship, Drug; Insulin; Isoproterenol;

1990
Protein secretion by rat submandibular glands in response to isoproterenol, alpha-methylnoradrenaline and clonidine during aging.
    Mechanisms of ageing and development, 1990, Volume: 54, Issue:3

    Topics: Aging; Animals; Clonidine; Isoelectric Focusing; Isoproterenol; Male; Nordefrin; Organ Size; Rats; R

1990
Dietary crude protein levels and the effect of isoproterenol on in vitro lipogenesis in the chicken.
    The Journal of nutrition, 1990, Volume: 120, Issue:12

    Topics: Aging; Animals; Body Weight; Chickens; Dietary Proteins; Fatty Acid Synthases; Isocitrate Dehydrogen

1990
Age-related differences in the depressor responses to sodium nitroprusside and nifedipine in anaesthetized rats.
    Journal of autonomic pharmacology, 1990, Volume: 10, Issue:1

    Topics: Aging; Animals; Blood Pressure; Ferricyanides; Heart Rate; Isoproterenol; Male; Nifedipine; Nitropru

1990
Force and oxygen consumption in the immature rabbit heart.
    Pediatric research, 1990, Volume: 27, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Heart Rate; Isoproterenol; Myocardial Contraction; Myocardium; Oxy

1990
Changes in lipid composition and isoproterenol- and ethanol-stimulated adenylate cyclase activity in aging Fischer rat bladders.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1

    Topics: Adenylyl Cyclases; Aging; Animals; Ethanol; Glucose; Guanylyl Imidodiphosphate; Isoproterenol; Lipid

1990
Age-related changes in myocardial relaxation and sarcoplasmic reticulum function.
    The American journal of physiology, 1990, Volume: 259, Issue:2 Pt 2

    Topics: Aging; Animals; Biological Transport; Blood Pressure; Calcium; Compliance; Diastole; Guinea Pigs; He

1990
Sympathomimetic protein secretion by young and aged lacrimal gland.
    Current eye research, 1986, Volume: 5, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Cyclic AMP; Isoenzymes; Isoproterenol; Lacrimal Apparat

1986
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Aging; B

1986
Beta adrenergic control of macromolecule synthesis in neonatal rat heart, kidney and lung: relationship to sympathetic neuronal development.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Aging; Animals; DNA; DNA Replication; Heart; Heart Conduction System; Isoproterenol; Kidney; Lung; N

1987
Subsensitivity of the failing human heart to isoprenaline and milrinone is related to beta-adrenoceptor downregulation.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:6

    Topics: Aging; Cardiotonic Agents; Coronary Disease; Electric Stimulation; Heart Failure; Humans; In Vitro T

1988
Developmental increase in the inotropic and cyclic AMP response to isoproterenol in embryonic and newly hatched chicks.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:9

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Animals, Newborn; Chick Embryo; Chickens; Cyclic AMP; I

1989
Ontogeny of isoproterenol-stimulated renin secretion from sheep renal cortical slices.
    The American journal of physiology, 1989, Volume: 256, Issue:6 Pt 2

    Topics: Aging; Animals; Animals, Newborn; Aspirin; Edetic Acid; Fetus; Gestational Age; Isoproterenol; Kidne

1989
Dissociation between c-fos gene expression and DNA synthesis in rat parotid glands.
    Archives of oral biology, 1989, Volume: 34, Issue:7

    Topics: Aging; Animals; Blotting, Northern; Carbachol; DNA; Epinephrine; Gene Expression; Isoproterenol; Mal

1989
Comparison of age-related changes in prostaglandin E1 and beta-adrenergic responsiveness of vascular smooth muscle in adult males.
    Journal of gerontology, 1989, Volume: 44, Issue:1

    Topics: Adult; Aging; Alprostadil; Dose-Response Relationship, Drug; Hand; Humans; Infusions, Intravenous; I

1989
Physiological response to isoproterenol and coupling of beta-adrenergic receptors in young and elderly human subjects.
    Journal of gerontology, 1989, Volume: 44, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Epinephrine; Heart Rate; Humans; Isoproterenol; Middle Aged;

1989
Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:3

    Topics: Aging; Animals; Aorta; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mesenteric A

1989
[Lack of negative regulation of beta-adrenoreceptor affinity by guanine nucleotides in embryonic membranes and its induction by the GTP-binding protein from mature protein].
    Biokhimiia (Moscow, Russia), 1989, Volume: 54, Issue:3

    Topics: Aging; Animals; Chick Embryo; Chickens; GTP-Binding Proteins; Guanine Nucleotides; Intracellular Mem

1989
Effect of age on acute regulation of beta-adrenergic responses in mononuclear leukocytes.
    Journal of gerontology, 1989, Volume: 44, Issue:5

    Topics: Adult; Aged; Aging; Alprostadil; Blood Pressure; Catecholamines; Cyclic AMP; Heart Rate; Humans; Iso

1989
A functional study of the development of the cardiac sympathetic neuroeffector junction in the SHR.
    Journal of hypertension, 1989, Volume: 7, Issue:5

    Topics: Aging; Animals; Blood Pressure; Clonidine; Desipramine; Dose-Response Relationship, Drug; Electric S

1989
Lymphocyte beta-adrenoceptor/effector complex in aging and dementia of the Alzheimer type.
    Alzheimer disease and associated disorders, 1989,Fall, Volume: 3, Issue:3

    Topics: Adult; Aged; Aging; Alzheimer Disease; Cyclic AMP; Humans; Isoproterenol; Lymphocytes; Receptors, Ad

1989
Age-related alteration in the catecholamine-sensitive adenylate cyclase system of the rat cerebral cortex.
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1989, Volume: 9, Issue:4

    Topics: Adenylyl Cyclases; Aging; Animals; Catecholamines; Cell Membrane; Cerebral Cortex; Enzyme Activation

1989
Effects of age on urinary bladder function in the male rat.
    The Journal of urology, 1989, Volume: 141, Issue:1

    Topics: Aging; Animals; Bethanechol; Bethanechol Compounds; Isoproterenol; Male; Muscle Contraction; Muscle,

1989
Altered beta-adrenoceptor internalization does not explain reduced beta-adrenergic responsiveness in the elderly.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 68, Issue:1

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Aging; Animals; Epinephrine; H

1989
Intracellular distribution of cardiac beta-adrenoceptors in SHR and WKY.
    Japanese circulation journal, 1989, Volume: 53, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Heart; Hypertension; In Vitro Techni

1989
Lipolytic response of bovine adipose tissue to alpha and beta adrenergic agents 30 days pre- and 120 days postpartum.
    General pharmacology, 1989, Volume: 20, Issue:3

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; A

1989
Myocardial response to alpha-agonist (phenylephrine) in relation to age.
    Critical care medicine, 1989, Volume: 17, Issue:12

    Topics: Adult; Aging; Animals; Depression, Chemical; Heart; Heart Atria; Heart Ventricles; Humans; In Vitro

1989
The response to isoproterenol-stimulated adenylate cyclase activity after administration of L-triiodothyronine is reduced in aged rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1989, Volume: 21, Issue:11

    Topics: Adenylyl Cyclases; Aging; Animals; Drug Interactions; Guanosine Triphosphate; Heart; Isoproterenol;

1989
Effects of isoproterenol treatment on the parathyroid glands in golden hamsters of different ages, with special reference to the frequency of lipid droplets.
    Acta anatomica, 1989, Volume: 136, Issue:3

    Topics: Aging; Animals; Calcium; Cricetinae; Female; Isoproterenol; Lipids; Male; Mesocricetus; Microscopy,

1989
Cardiovascular regulatory functions in elderly patients with hypertension.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Aldosterone; Blood Pressure; Cardiovascular System; Female; Heart; H

1989
Vasodilator responses to dopamine in rat perfused mesentery are age-dependent.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Aging; Animals; Dopamine; Drug Interactions; In Vitro Techniques; Isoproterenol; Male; Nitroprusside

1989
The effects of ageing on neuronal uptake of noradrenaline in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:2

    Topics: Aging; Animals; Cocaine; Corticosterone; Decerebrate State; Heart; Heart Rate; Hemodynamics; Isoprot

1989
Age-associated alterations in hepatic beta-adrenergic receptor/adenylate cyclase complex.
    The American journal of physiology, 1987, Volume: 253, Issue:3 Pt 1

    Topics: Adenylyl Cyclases; Aging; Animals; Binding, Competitive; Cell Separation; Enzyme Activation; Glycoge

1987
Emergence of beta adrenergic-responsive hepatic glycogenolysis in male rats during post-maturational aging.
    Biochemical and biophysical research communications, 1987, Sep-15, Volume: 147, Issue:2

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Epinephrine; Glucagon; Glucose; Gly

1987
Stimulation and inhibition of lipolysis in isolated rat adipocytes: evidence for age-related changes in responses to forskolin and PGE1.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1987, Volume: 19, Issue:8

    Topics: Adipose Tissue; Aging; Animals; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Lipolysis

1987
Age-related and testicular regression-induced changes in adenosine 3',5'-monophosphate responses in cultured hamster Sertoli cells.
    Endocrinology, 1988, Volume: 122, Issue:2

    Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Aging; Animals; Cells, Cultured; Cholera Toxin; Col

1988
Iontophoretic study of adrenergic and cholinergic skin vessel reactivity in normal ageing and Alzheimer's disease.
    Gerontology, 1987, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Autonomic Agents; Humans; Iont

1987
Age-associated decrease in beta-adrenergic receptors and adenylate cyclase activity in rat brown adipose tissue.
    Journal of gerontology, 1988, Volume: 43, Issue:3

    Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Aging; Animals; Body Temperature Regulation; Colforsin; El

1988
Effects of chronic isoproterenol administration on beta 1-adrenoceptors and growth of pancreas of young and adult rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 188, Issue:2

    Topics: Aging; Animals; Atenolol; Butoxamine; Cell Differentiation; Cell Membrane; Dihydroalprenolol; DNA; I

1988
Glandular adenylate cyclase system in genetic hypertension: age-dependent response to catecholamines.
    European journal of pharmacology, 1988, Mar-15, Volume: 147, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Dose-Response Relationship, Drug; Fluorides; Hyperten

1988
[Tetracycline and energy metabolism of cardiac mitochondria in old rabbits after isoproterenol premedication].
    Bratislavske lekarske listy, 1988, Volume: 89, Issue:5

    Topics: Adenine Nucleotides; Adenosine Triphosphatases; Aging; Animals; Electron Transport Complex IV; Energ

1988
Noradrenergic modulation of olfactory bulb excitability in the postnatal rat.
    Brain research, 1988, Jul-01, Volume: 470, Issue:1

    Topics: Action Potentials; Aging; Animals; Electric Stimulation; Female; Isoproterenol; Male; Norepinephrine

1988
Age does not alter human vascular and nonvascular beta 2-adrenergic responses to isoproterenol.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:5

    Topics: Adult; Aged; Aging; Blood Glucose; Humans; Infusions, Intravenous; Insulin; Isoproterenol; Male; Mid

1988
Increased beta-adrenergic receptors in the light-density membrane fraction in lungs from senescent rats.
    Journal of gerontology, 1988, Volume: 43, Issue:6

    Topics: Aging; Animals; Centrifugation; Female; Isoproterenol; Lung; Membranes; Myocardium; Rats; Rats, Inbr

1988
Ontogeny of alpha- and beta-adrenergic anorexia in rats.
    The American journal of physiology, 1988, Volume: 255, Issue:6 Pt 2

    Topics: Aging; Animals; Anorexia; Appetite; Appetite Depressants; Feeding and Eating Disorders; Female; Isop

1988
Properties of cardiac alpha- and beta-adrenoceptors in spontaneously hypertensive rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:4

    Topics: Aging; Animals; Cardiomegaly; Electric Stimulation; Hypertension; In Vitro Techniques; Isoproterenol

1988
Isoproterenol-sensitive adenylate cyclase in glomeruli isolated from young and adult rat renal cortex.
    General pharmacology, 1985, Volume: 16, Issue:3

    Topics: Adenylyl Cyclases; Aging; Alkaline Phosphatase; Animals; Enzyme Activation; Fluorides; gamma-Glutamy

1985
Cyclic AMP in normal and sympathetically aneural chick hearts during development.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:8

    Topics: Adrenergic beta-Antagonists; Aging; Animals; Chick Embryo; Cyclic AMP; Embryonic and Fetal Developme

1986
Accumulation of adenosine 3',5'-monophosphate in slices of rat cerebral cortex induced by alpha-adrenergic agonists. I. Responses to methoxamine and norepinephrine in adult and neonatal tissue.
    Molecular and cellular biochemistry, 1987, Volume: 73, Issue:2

    Topics: Adenosine; Adrenergic alpha-Antagonists; Aging; Animals; Animals, Newborn; Cerebral Cortex; Cyclic A

1987
Postnatal development of beta-adrenergic response in ventricular muscle of the rat heart.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:3

    Topics: Adrenergic beta-Agonists; Aging; Animals; Female; Heart; In Vitro Techniques; Isoproterenol; Male; R

1988
Comparison between the effects of aging on antagonist and agonist interactions with beta-adrenergic receptors on human mononuclear and polymorphonuclear leukocyte membranes.
    Journal of gerontology, 1988, Volume: 43, Issue:6

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aging; Drug Interactions; Female

1988
Effects of neonatal treatment with 6-aminonicotinamide on basal and isoproterenol-stimulated ornithine decarboxylase activity in cerebellum of the development rat.
    Biochemical pharmacology, 1985, Sep-15, Volume: 34, Issue:18

    Topics: 6-Aminonicotinamide; Aging; Animals; Animals, Newborn; Body Weight; Cerebellum; Enzyme Activation; I

1985
cAMP metabolism and lipolysis in brown adipocytes of hamsters consuming a cafeteria diet.
    The American journal of physiology, 1985, Volume: 248, Issue:2 Pt 1

    Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Aging; Animals; Body Temperature Regulation; Colforsin; Cr

1985
Influences of age on the positive inotropic effect mediated by alpha- and beta-adrenoceptors in rat ventricular strips.
    Developmental pharmacology and therapeutics, 1985, Volume: 8, Issue:1

    Topics: Aging; Animals; Atenolol; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Phenylep

1985
Hepatic adenylate cyclase. Development-dependent coupling to the beta-adrenergic receptor in the neonate.
    The Journal of biological chemistry, 1985, Sep-05, Volume: 260, Issue:19

    Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Cell Membrane; Cholera Toxin; Dihydroalprenolol

1985
Effect of aging on the response of the cerebral cortex to noradrenergic denervation.
    Gerontology, 1985, Volume: 31, Issue:5

    Topics: Adenylyl Cyclases; Aging; Animals; Cerebral Cortex; Cyclic AMP; Dominance, Cerebral; Hydroxydopamine

1985
Age-related reduction of beta-adrenoceptor sensitivity in rat heart occurs by multiple mechanisms.
    Gerontology, 1985, Volume: 31, Issue:6

    Topics: Adenylyl Cyclases; Aging; Animals; Cyclic AMP; Dihydroalprenolol; Heart; Isoproterenol; Kinetics; Ma

1985
Decreased beta-adrenergic responsiveness during senescence.
    Federation proceedings, 1986, Volume: 45, Issue:1

    Topics: Adenylyl Cyclases; Aging; Animals; Blood Platelets; Heart; Humans; In Vitro Techniques; Isoprotereno

1986
Effect of age on beta adrenergic relaxation of the rat jugular vein.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:1

    Topics: Age Factors; Aging; Animals; In Vitro Techniques; Isoproterenol; Jugular Veins; Male; Rats; Rats, In

1986
Lymphocyte protein kinase activity in cells from young and elderly men and women.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:3

    Topics: Adult; Aged; Aging; Colforsin; Cyclic AMP; Cyclic GMP; Enzyme Activation; Female; Humans; Isoprotere

1985
Sarcolemmal Na+-Ca2+ exchange during the development of genetically determined cardiomyopathy.
    Biochemical and biophysical research communications, 1985, Dec-17, Volume: 133, Issue:2

    Topics: Aging; Animals; Biological Transport; Calcium; Cardiomyopathies; Cricetinae; Isoproterenol; Mesocric

1985
Developmental alteration in adrenergic regulation of hepatic glycogen phosphorylase.
    Japanese journal of pharmacology, 1986, Volume: 40, Issue:1

    Topics: Aging; Animals; Cyclic AMP; Epinephrine; In Vitro Techniques; Isoproterenol; Liver; Liver Glycogen;

1986
Autonomic interactions in the aging heart: age-associated decrease in muscarinic cholinergic receptor mediated inhibition of beta-adrenergic activation of adenylate cyclase.
    Mechanisms of ageing and development, 1986, Volume: 34, Issue:3

    Topics: Adenylyl Cyclases; Aging; Animals; Atropine; Carbachol; Cell Membrane; Enzyme Activation; Guanosine

1986
Beta-adrenergic receptors in the elderly are not less sensitive to timolol.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:2

    Topics: Adult; Aged; Aging; Blood Pressure; Female; Heart Rate; Humans; Injections, Intravenous; Isoproteren

1986
Effect of age on the formation of cyclic nucleotides in guinea-pig tracheal smooth muscle in response to pharmacological agents.
    European journal of pharmacology, 1986, Jun-17, Volume: 125, Issue:2

    Topics: Aging; Alprostadil; Animals; Carbachol; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Guinea Pig

1986
Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: Adult; Aged; Aging; Cyclic AMP; Humans; Isoproterenol; Male; Middle Aged; Muscle Relaxation; Muscle,

1986
Regulation of beta adrenergic receptors on rat mononuclear leukocytes by stress: receptor redistribution and down-regulation are altered with aging.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: Aging; Animals; Cyclic AMP; Dihydroalprenolol; Isoproterenol; Male; Monocytes; Propanolamines; Propr

1987
[Age dependent quantitative evaluations of sensitivity changes in beta adrenergic receptors to isoprenaline and propranolol].
    Kardiologia polska, 1986, Volume: 29, Issue:7

    Topics: Adult; Aged; Aging; Humans; Isoproterenol; Male; Middle Aged; Propranolol; Receptors, Adrenergic, be

1986
Effects of thyroid hormone on beta-adrenergic responsiveness of aging cardiovascular systems.
    The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2

    Topics: Aging; Animals; Body Weight; Cardiovascular Physiological Phenomena; Catecholamines; Decerebrate Sta

1987
Beta-adrenergic receptors, glucagon receptors, and their relationship to adenylate cyclase in rat liver during aging.
    Endocrinology, 1987, Volume: 120, Issue:4

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Glucagon; Guanine Nucleotides; Guan

1987
Role of alpha-adrenoceptors for adipocyte size in man.
    European journal of clinical investigation, 1987, Volume: 17, Issue:1

    Topics: Adipose Tissue; Adolescent; Adult; Aging; Child; Child, Preschool; Cross-Sectional Studies; Female;

1987
Decrease in force potentiation and appearance of alpha-adrenergic mediated contracture in aging rat skeletal muscle.
    Pflugers Archiv : European journal of physiology, 1987, Volume: 408, Issue:3

    Topics: Aging; Animals; Catecholamines; Female; In Vitro Techniques; Isoproterenol; Muscle Contraction; Musc

1987
Diet restriction retards the age-related loss of beta-adrenergic receptors and adenylate cyclase activity in rat lung.
    Journal of gerontology, 1987, Volume: 42, Issue:4

    Topics: Adenylyl Cyclases; Aging; Animal Nutritional Physiological Phenomena; Animals; Colforsin; Diet; Epin

1987
Increased incidence of isoproterenol-induced ventricular fibrillation in aging rats.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:4

    Topics: Aging; Animals; Blood Pressure; Electrocardiography; Heart Rate; Isoproterenol; Male; Rats; Receptor

1987
Differential regulation of testicular transferrin and androgen-binding protein secretion in primary cultures of rat Sertoli cells.
    Endocrinology, 1986, Volume: 118, Issue:1

    Topics: Aging; Androgen-Binding Protein; Animals; Blood; Cell Count; Cells, Cultured; Deferoxamine; Epiderma

1986
Melanocyte-stimulating hormone and the regulation of tyrosinase activity in hair follicular melanocytes of the mouse.
    The Journal of endocrinology, 1986, Volume: 111, Issue:2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aging; Animals; Catechol Oxidase; Female; Hair; Hair Color;

1986
Regulation of lipolysis during the neonatal period. Importance of thyrotropin.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:5

    Topics: Adenosine Deaminase; Adipose Tissue; Adult; Aging; Child; Child, Preschool; Epinephrine; Gestational

1988
Effects of arterial hypoxia and isoproterenol on in vitro postnatal intestinal circulation.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 2

    Topics: Aging; Animals; Animals, Newborn; Hypoxia; Intestines; Isoproterenol; Jejunum; Oxygen Consumption; R

1988
Heart lactate dehydrogenase isoenzymes as a function of age, exercise and experimental necrosis.
    Indian journal of experimental biology, 1988, Volume: 26, Issue:8

    Topics: Aging; Animals; Isoenzymes; Isoproterenol; L-Lactate Dehydrogenase; Myocardium; Necrosis; Physical C

1988
[Age-related characteristics of a change in cardiac systolic and diastolic functions under the influence of the adrenergic stimulants isadrin and mezaton (based on data from a computer analysis of the echocardiogram)].
    Kardiologiia, 1988, Volume: 28, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aging; Computers; Diastole; Echocardiography; Humans; Isoproterenol;

1988
Metabolic hyperemia is reduced in adult vs. immature guinea pig hearts.
    The American journal of physiology, 1988, Volume: 255, Issue:6 Pt 2

    Topics: Adenosine; Aging; Animals; Coronary Circulation; Guinea Pigs; Heart; In Vitro Techniques; Isoprotere

1988
Milrinone effects in the isolated immature rabbit heart.
    Developmental pharmacology and therapeutics, 1988, Volume: 11, Issue:6

    Topics: Aging; Animals; Blood Pressure; Cardiotonic Agents; Heart; Heart Rate; In Vitro Techniques; Isoprote

1988
Comparative electrophysiological response of young and old rat myocardium to pharmacological agents.
    General pharmacology, 1988, Volume: 19, Issue:6

    Topics: Action Potentials; Aging; Amiloride; Animals; Electric Stimulation; Female; Heart; Isoproterenol; Ni

1988
[Aging and cardiac function].
    Rinsho byori. The Japanese journal of clinical pathology, 1988, Volume: 36, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aging; Echocardiography; Female; Heart; Heart Function Tests; Hemody

1988
Cloning and sequencing of cDNA encoding a rat salivary cysteine proteinase inhibitor inducible by beta-adrenergic agonists.
    The Journal of biological chemistry, 1988, Dec-05, Volume: 263, Issue:34

    Topics: Aging; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cloning, Molecular; Cysteine

1988
Aging and aortic impedance in beagle dogs.
    Mechanisms of ageing and development, 1988, Volume: 42, Issue:1

    Topics: Aging; Animals; Aorta; Dogs; Female; Hemodynamics; Isoproterenol; Nitroprusside; Phenylephrine; Vasc

1988
Inotropic responses change during postnatal maturation in rabbit.
    The American journal of physiology, 1988, Volume: 255, Issue:2 Pt 2

    Topics: Aging; Animals; Animals, Newborn; Cardiotonic Agents; Colforsin; Female; Heart; Imidazoles; Isoprote

1988
Aging and rat pacemaker sensitivity to beta-adrenoceptor agonists.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1987, Volume: 20, Issue:5

    Topics: Action Potentials; Aging; Animals; Heart Atria; Heart Rate; Isoproterenol; Male; Myocardial Contract

1987
Age-dependent changes in the response of isolated beagle coronary arteries to transmural electrical stimulation and catecholamines.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Acetylcholine; Aging; Animals; Catecholamines; Coronary Circulation; Coronary Vessels; Dinoprost; Do

1986
Responsiveness to vasoconstrictor and dilator agents of senescent beagle cerebral arteries.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:4

    Topics: Adenosine; Aging; Animals; Basilar Artery; Cerebral Arteries; Dogs; Epoprostenol; Female; Histamine;

1986
Alterations with age of the response to vasodilator agents in isolated mesenteric arteries of the beagle.
    British journal of pharmacology, 1986, Volume: 89, Issue:4

    Topics: Acetylcholine; Adenosine; Aging; Animals; Dogs; Endothelium; Epoprostenol; Female; Histamine; In Vit

1986
Altered endothelial modulation of vascular tone in aging and hypertension.
    Blood vessels, 1987, Volume: 24, Issue:3

    Topics: Adenosine; Aging; Animals; Blood Vessels; Desoxycorticosterone; Dose-Response Relationship, Drug; En

1987
Temperature-dependence of maturation of chronotropic and inotropic responses to isoproterenol.
    Developmental pharmacology and therapeutics, 1987, Volume: 10, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Electric Stimulation; Female; Heart Rate; Isoproterenol; Male; Myo

1987
Development and properties of the secretory response in rat sweat glands: relationship to the induction of cholinergic function in sweat gland innervation.
    Developmental biology, 1987, Volume: 123, Issue:1

    Topics: Aging; Animals; Atropine; Electric Stimulation; Isoproterenol; Norepinephrine; Rats; Sciatic Nerve;

1987
[Regulation of isoproterenol-induced salivary gland hyperplasia in young and old mice by substances affecting the serotonin- and dopaminergic systems].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:4

    Topics: Aging; Animals; Female; Freund's Adjuvant; Hyperplasia; Isoproterenol; Levodopa; Mice; Mice, Inbred

1986
Ornithine decarboxylase activity in the neonatal rat heart following prenatal exposure to ethylene glycol monomethyl ether.
    Drug and chemical toxicology, 1986, Volume: 9, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Ethylene Glycols; Female; Isoproterenol; Male; Myocar

1986
Alterations of rat cardiac adenylate cyclase activity with age.
    European journal of pharmacology, 1986, Jul-15, Volume: 126, Issue:1-2

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Glucagon; Guanylyl Imidodiphosphate; Isoproterenol; Ma

1986
Age dependence of adenylate cyclase in guinea pig ureter homogenate.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1

    Topics: Adenylyl Cyclases; Aging; Alprostadil; Animals; Colforsin; Enzyme Activation; Ethanol; Guanosine Tri

1986
Effect of age on blood pressure and small vessel reactivity in male rabbits.
    Blood vessels, 1986, Volume: 23, Issue:6

    Topics: Aging; Animals; Blood Pressure; Female; Heart Rate; Histamine; Isoproterenol; Male; Muscle, Smooth,

1986
Effects of dystrophy and age on hamster tracheal smooth muscle function.
    Respiration physiology, 1986, Volume: 66, Issue:2

    Topics: Aging; Airway Resistance; Animals; Carbachol; Cricetinae; Histamine; In Vitro Techniques; Isoprotere

1986
Developmental changes in the effects of beta-adrenergic blocking concentrations of propranolol on canine Purkinje fibers.
    Developmental pharmacology and therapeutics, 1986, Volume: 9, Issue:6

    Topics: Action Potentials; Aging; Animals; Animals, Newborn; Dogs; Heart Conduction System; Isoproterenol; P

1986
Chronotropic and inotropic effects on atria of chronic ethanol ingestion in the aging rat.
    Alcohol and drug research, 1987, Volume: 7, Issue:4

    Topics: Aging; Animals; Arrhythmias, Cardiac; Depression, Chemical; Ethanol; Heart Atria; Heart Rate; Isopro

1987
Developmental considerations in neonatal failure.
    Hospital practice (Office ed.), 1985, Jan-15, Volume: 20, Issue:1

    Topics: Aging; Animals; Blood Circulation; Body Temperature Regulation; Cardiac Output; Digitalis; Digoxin;

1985
Neonatal steroid treatment reduces catecholamine-induced increases in pineal serotonin N-acetyltransferase activity.
    Journal of neurochemistry, 1985, Volume: 44, Issue:4

    Topics: Acetyltransferases; Aging; Animals; Animals, Newborn; Arylamine N-Acetyltransferase; Catecholamines;

1985
Drinking by senescent and adult rats in response to regulatory challenges.
    Neurobiology of aging, 1985,Spring, Volume: 6, Issue:1

    Topics: Aging; Animals; Drinking; Eating; Female; Isoproterenol; Male; Rats; Rats, Inbred Strains; Saline So

1985
Electrophysiological analysis of the nature of adrenoceptors in the rat basilar artery during development.
    British journal of pharmacology, 1985, Volume: 86, Issue:1

    Topics: Action Potentials; Aging; Animals; Basilar Artery; Female; Iontophoresis; Isoproterenol; Male; Membr

1985
Regulation of the adenosine cyclic 3',5'-monophosphate content of rat cerebral cortex: ontogenetic development of the responsiveness to catecholamines and adenosine.
    Molecular pharmacology, 1973, Volume: 9, Issue:6

    Topics: Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic alp

1973
Changes in the carotid pulse which occur with age and hypertension.
    American heart journal, 1966, Volume: 71, Issue:6

    Topics: Adult; Aging; Amyl Nitrite; Angiotensin II; Arteriosclerosis; Blood Pressure; Carotid Arteries; Elec

1966
Adenylate cyclase activity in rat submandibular gland during postnatal development.
    Life sciences, 1974, Jan-16, Volume: 14, Issue:2

    Topics: Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Body Weight; Carbon Radioisotopes; Cyclic AMP;

1974
Increased sensitivity of sinoatrial pace-maker to acetylcholine and to catecholamines at the onset of autonomic neuroeffector transmission in chick embryo heart.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 191, Issue:3

    Topics: Acetylcholine; Aging; Animals; Atropine; Autonomic Fibers, Postganglionic; Chick Embryo; Electric St

1974
Change of the relative proportion of various forms of phosphoenolpyruvate carboxykinase in chicken liver possibly associated with enhanced gluconeogenesis.
    FEBS letters, 1974, Aug-01, Volume: 43, Issue:3

    Topics: Aging; Animals; Bicarbonates; Carbon Radioisotopes; Chickens; Chromatography, Ion Exchange; Cold Tem

1974
The effect of prostaglandin E2 on the arterial blood pressure of normotensive and spontaneously hypertensive rats.
    British journal of pharmacology, 1974, Volume: 51, Issue:4

    Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship,

1974
Interrelation of aging, gonadial steroidal hormone activity and lipid metabolism.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1974, Volume: 141

    Topics: Aging; Animals; Castration; Cholesterol; Female; Gonadal Steroid Hormones; Gonads; Humans; Isoproter

1974
Myocardial loss of functional magnesium. II. In cardiomyopathies of diverse etiology.
    Recent advances in studies on cardiac structure and metabolism, 1972, Volume: 1

    Topics: Adult; Age Factors; Aging; Animals; Calcium; Cricetinae; Heart; Heart Diseases; Heart Failure; Human

1972
Possible changes in tissue sensitivity in the age-dependent stimulation of DNA synthesis in vivo.
    Journal of gerontology, 1973, Volume: 28, Issue:3

    Topics: Aging; Animals; Body Weight; DNA; Isoproterenol; Male; Rats; Submandibular Gland; Thymidine; Time Fa

1973
The effect of age on -adrenoceptor activity in tracheal smooth muscle.
    British journal of pharmacology, 1973, Volume: 47, Issue:1

    Topics: Aging; Animals; Guinea Pigs; Isoproterenol; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Adr

1973
Age-dependent regulation of mammalian DNA synthesis and cell division in vivo by glucocorticoids.
    Experimental gerontology, 1974, Volume: 9, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenalectomy; Age Factors; Aging; Animals; Cell Division; DNA; Drug Resist

1974
Age-dependent regulation of isoproterenol-stimulated DNA synthesis in rat salivary gland in vivo.
    Experimental gerontology, 1974, Volume: 9, Issue:1

    Topics: Age Factors; Aging; Animals; Circadian Rhythm; Cycloheximide; Dactinomycin; DNA; Enzyme Induction; I

1974
Rat atrial alkaline phosphatase activity and its response to isoprenaline (isoproterenol) during postnatal development.
    Journal of molecular and cellular cardiology, 1972, Volume: 4, Issue:3

    Topics: Aging; Alkaline Phosphatase; Animals; Animals, Newborn; Enzyme Induction; Heart Atria; Histocytochem

1972
The supersensitivity of isolated rabbit atria and aortic strips produced by 6-hydroxydopamine.
    European journal of pharmacology, 1972, Volume: 18, Issue:2

    Topics: Aging; Animals; Aorta; Barium; Dimethylphenylpiperazinium Iodide; Dopamine; Drug Interactions; Drug

1972
Further studies on the effect of ageing on beta-adrenoceptor activity of rat aorta.
    British journal of pharmacology, 1971, Volume: 42, Issue:2

    Topics: Aging; Animals; Aorta, Thoracic; Female; In Vitro Techniques; Isoproterenol; Male; Nitrites; Phentol

1971
[Therapy of acute myocardial infarct with particular reference to arrhythmia and myocardial contractibility disorders].
    Giornale di gerontologia, 1971, Volume: 19, Issue:1

    Topics: Adult; Aged; Aging; Arrhythmias, Cardiac; Atropine; Cardiac Glycosides; Cortisone; Electric Counters

1971
Characteristics of reactive hyperemia in old and young dogs.
    Angiology, 1965, Volume: 16, Issue:10

    Topics: Acetylcholine; Aging; Animals; Blood Flow Velocity; Dogs; Epinephrine; Histamine; Hyperemia; Isoprot

1965
[The relaxing response of the coronary vessels to sympathic stimuli diminishes with age].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Aug-31, Volume: 41, Issue:16

    Topics: Aging; Animals; Cattle; Coronary Vessels; Epinephrine; Horses; In Vitro Techniques; Isoproterenol; T

1965