Page last updated: 2024-10-29

isoproterenol and Adrenal Cancer

isoproterenol has been researched along with Adrenal Cancer in 20 studies

Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.

Research Excerpts

ExcerptRelevanceReference
"Six amine, amino acid and peptide derivatives derived from 1,3-dipropyl-8-(p-carboxymethylphenyl)xanthine, a functionalized congener of 1,3-dipropyl-8-phenylxanthine, have been investigated as antagonists at A2 adenosine receptors stimulatory to adenylate cyclase in membranes from rat pheochromocytoma PC 12 cells and human platelets and at A1 adenosine receptors inhibitory to adenylate cyclase from rat fat cells."7.67Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells. ( Daly, JW; Jacobson, KA; Kirk, KL; Ukena, D, 1986)
"Six amine, amino acid and peptide derivatives derived from 1,3-dipropyl-8-(p-carboxymethylphenyl)xanthine, a functionalized congener of 1,3-dipropyl-8-phenylxanthine, have been investigated as antagonists at A2 adenosine receptors stimulatory to adenylate cyclase in membranes from rat pheochromocytoma PC 12 cells and human platelets and at A1 adenosine receptors inhibitory to adenylate cyclase from rat fat cells."3.67Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells. ( Daly, JW; Jacobson, KA; Kirk, KL; Ukena, D, 1986)
"A direct binding study of radioligand [3H]dihydroalprenolol (DHA), a potent beta-adrenergic antagonist, was performed on the particulate fractions of four adrenocortical adenomas (three cortisol-producing adenomas and one aldosterone-producing adenoma) and normal adrenal tissues."3.66Presence of ectopic beta-adrenergic receptors on human adrenocortical cortisol-producing adenomas. ( Fujita, T; Hirata, Y; Matsukura, S; Sueoka, S; Uchihashi, M, 1981)
"Metanephrines were adsorbed from plasma onto a cation-exchange column and eluted with ammoniacal methanol."1.29Determination of metanephrines in plasma by liquid chromatography with electrochemical detection. ( Armando, I; Eisenhofer, G; Goldstein, DS; Keiser, HR; Kopin, IJ; Lenders, JW, 1993)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199014 (70.00)18.7374
1990's5 (25.00)18.2507
2000's1 (5.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyamura, N1
Taguchi, T1
Murata, Y1
Taketa, K1
Iwashita, S1
Matsumoto, K1
Nishikawa, T1
Toyonaga, T1
Sakakida, M1
Araki, E1
Hirata, Y1
Uchihashi, M1
Sueoka, S1
Matsukura, S1
Fujita, T1
Snavely, MD1
Motulsky, HJ1
Moustafa, E1
Mahan, LC1
Insel, PA1
Tsujimoto, G1
Manger, WM1
Hoffman, BB2
Cases, A1
Bono, M1
Gaya, J1
Jimenez, W1
Calls, J1
Esforzado, N1
Rivera, F1
Revert, L1
Radó, J1
Arányi, J1
Deák, G1
Rétai, G1
Lenders, JW1
Eisenhofer, G1
Armando, I1
Keiser, HR1
Goldstein, DS1
Kopin, IJ1
Venter, BR1
Venter, JC1
Kaplan, NO1
Greenacre, JK1
Conolly, ME1
Donta, ST1
Shanley, JD1
Carranza, MC1
Simón, MA1
Torres, A1
Calle, C1
Prokocimer, PG1
Maze, M1
Vickery, RG1
Lönnroth, P1
Wesslau, C1
Stenström, G1
Tisell, LE1
Smith, U1
Katz, MS1
Kelly, TM1
Dax, EM1
Pineyro, MA1
Partilla, JS1
Gregerman, RI1
Ratge, D1
Wisser, H1
Ukena, D1
Daly, JW1
Kirk, KL1
Jacobson, KA1
Sapira, JD1
Klaniecki, T1
Ratkin, G1
Deptalla, H1
Wiegershausen, B1
Lydtin, H1
Fujino, T1
Mashiba, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pheochromocytoma Randomised Study Comparing Adrenoreceptor Inhibiting Agents for Preoperative Treatment[NCT01379898]Phase 4134 participants (Actual)Interventional2011-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for isoproterenol and Adrenal Cancer

ArticleYear
[Beta-receptor-blocking agents and their current clinical significance].
    Das Deutsche Gesundheitswesen, 1968, Dec-12, Volume: 23, Issue:50

    Topics: Adrenal Gland Neoplasms; Amino Alcohols; Angina Pectoris; Anilides; Arrhythmias, Cardiac; Blood Pres

1968
[Beta-receptor-blocking agents and anesthesia].
    Die Medizinische Welt, 1969, Aug-30, Volume: 35

    Topics: Adrenal Gland Neoplasms; Anesthesia; Angina Pectoris; Arrhythmias, Cardiac; Asthma; Cardiomyopathy,

1969
[Catecholamine cardiopathy].
    Kokyu to junkan. Respiration & circulation, 1972, Volume: 20, Issue:11

    Topics: Adrenal Gland Neoplasms; Adult; Animals; Catecholamines; Cerebrovascular Disorders; Electrocardiogra

1972

Other Studies

17 other studies available for isoproterenol and Adrenal Cancer

ArticleYear
Inherited adrenocorticotropin-independent macronodular adrenal hyperplasia with abnormal cortisol secretion by vasopressin and catecholamines: detection of the aberrant hormone receptors on adrenal gland.
    Endocrine, 2002, Volume: 19, Issue:3

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adrenergic beta-Agonists; Adrenocor

2002
Presence of ectopic beta-adrenergic receptors on human adrenocortical cortisol-producing adenomas.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 53, Issue:5

    Topics: Adenoma; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Cell Membrane;

1981
beta-Adrenergic receptor subtypes in the rat renal cortex. Selective regulation of beta 1-adrenergic receptors by pheochromocytoma.
    Circulation research, 1982, Volume: 51, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Binding, Competitive; Epinephrine; Hydroxydopamines; Iodocyanopind

1982
Desensitization of beta-adrenergic receptors by pheochromocytoma.
    Endocrinology, 1984, Volume: 114, Issue:4

    Topics: Adipose Tissue; Adrenal Gland Neoplasms; Animals; Body Weight; Cell Membrane; Cyclic AMP; Energy Int

1984
Reversible decrease of surface beta 2-adrenoceptor number and response in lymphocytes of patients with pheochromocytoma.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Adult; Aged; Case-Control Studies; Catecholami

1995
[Pseudophaeochromocytoma (hypertensive crisis as a result of beta receptor hypersensitivity?)].
    Orvosi hetilap, 1993, Apr-25, Volume: 134, Issue:17

    Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Catecholamines; Drug Hypersensitivity; Humans;

1993
Determination of metanephrines in plasma by liquid chromatography with electrochemical detection.
    Clinical chemistry, 1993, Volume: 39, Issue:1

    Topics: Adrenal Gland Neoplasms; Chromatography, High Pressure Liquid; Epinephrine; Humans; Isoproterenol; M

1993
Affinity isolation of cultured tumor cells by means of drugs and hormones covalently bound to glass and Sepharose beads.
    Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:6

    Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Cell Membrane; Cell Separation; Cells

1976
Desensitization of the beta-adrenoceptor of lymphocytes from normal subjects and patients with phaeochromocytoma: studies in vivo.
    British journal of clinical pharmacology, 1978, Volume: 5, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenal Gland Neoplasms; Albuterol; Cyclic AMP; Humans; In Vitr

1978
Reovirus type 3 binds to antagonist domains of the beta-adrenergic receptor.
    Journal of virology, 1990, Volume: 64, Issue:2

    Topics: Adrenal Gland Neoplasms; Animals; Binding, Competitive; Dihydroalprenolol; Glioma; Isoproterenol; Ki

1990
Chronic and endogenous regulation of insulin receptors by catecholamines in adipocytes from patients with a phaeochromocytoma.
    Bioscience reports, 1990, Volume: 10, Issue:2

    Topics: Adipose Tissue; Adrenal Gland Neoplasms; Adult; Female; Glycerol; Humans; Insulin; Isoproterenol; Ma

1990
Mechanism for desensitization of beta-adrenergic receptor-stimulated lipolysis in adipocytes from rats harboring pheochromocytoma.
    Endocrinology, 1988, Volume: 123, Issue:1

    Topics: Adipose Tissue; Adrenal Gland Neoplasms; Animals; Cyclic AMP; Isoproterenol; Kinetics; Lipolysis; Ph

1988
Reduced insulin binding to human fat cells following beta-adrenergic stimulation--experimental evidence and studies in patients with a phaeochromocytoma.
    Diabetologia, 1985, Volume: 28, Issue:12

    Topics: Adipose Tissue; Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Adult; Aged; Catecholamines; F

1985
Ectopic beta-adrenergic receptors coupled to adenylate cyclase in human adrenocortical carcinomas.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:5

    Topics: Adenylyl Cyclases; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Aged

1985
Alpha- and beta-adrenergic receptor activity in circulating blood cells of patients with phaeochromocytoma: effects of adrenalectomy.
    Acta endocrinologica, 1986, Volume: 111, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Blood Platelets; Cyclic AMP; Dihydroalprenolol; Epine

1986
Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells.
    Life sciences, 1986, Mar-03, Volume: 38, Issue:9

    Topics: Adenylyl Cyclases; Adipose Tissue; Adrenal Gland Neoplasms; Animals; Blood Platelets; Cell Line; Cyc

1986
"Non-pheochromocytoma".
    JAMA, 1970, Jun-29, Volume: 212, Issue:13

    Topics: Adrenal Gland Neoplasms; Adult; Arteriovenous Fistula; Asthma; Celiac Disease; Child, Preschool; Dia

1970