isoproterenol has been researched along with Acute Liver Injury, Drug-Induced in 14 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " in isoproterenol-induced myocardial infarction and CCl4-induced hepatotoxicity in rats." | 3.70 | Antioxidant activity of AO-8, a herbal formulation in vitro and in vivo experimental models. ( Gopumadhavan, S; Mitra, SK; Sundaram, R; Venkataranganna, MV, 1999) |
| "Hepatic necrosis produced by carbon tetrachloride (0." | 3.68 | Potentiation of carbon tetrachloride hepatotoxicity by phenylpropanolamine. ( Harbison, RD; James, RC; Roberts, SM; Seng, JE, 1991) |
| "Liver dysfunction is a common side effect associated with the treatment of dasatinib and its mechanism is poorly understood." | 1.42 | Autophagy protects against dasatinib-induced hepatotoxicity via p38 signaling. ( Chen, C; Dai, J; He, Q; Luo, P; Ma, J; Ma, S; Shao, J; Wang, J; Yang, B; Yang, X, 2015) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (78.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Chen, M | 2 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 3 |
| Dawson, S | 1 |
| Stahl, S | 2 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 2 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Soeda, J | 1 |
| Mouralidarane, A | 1 |
| Ray, S | 1 |
| Novelli, M | 1 |
| Thomas, S | 1 |
| Roskams, T | 1 |
| Diehl, AM | 1 |
| Oben, JA | 2 |
| Zou, Z | 1 |
| Shen, Z | 1 |
| Cai, Y | 1 |
| Chen, Y | 2 |
| Chen, S | 1 |
| Yang, X | 1 |
| Wang, J | 1 |
| Dai, J | 1 |
| Shao, J | 1 |
| Ma, J | 1 |
| Chen, C | 1 |
| Ma, S | 1 |
| He, Q | 1 |
| Luo, P | 1 |
| Yang, B | 1 |
| Saeedi Saravi, SS | 1 |
| Ghazi-Khansari, M | 1 |
| Ejtemaei Mehr, S | 1 |
| Nobakht, M | 1 |
| Mousavi, SE | 1 |
| Dehpour, AR | 1 |
| Mitra, SK | 1 |
| Venkataranganna, MV | 1 |
| Sundaram, R | 1 |
| Gopumadhavan, S | 1 |
| Roberts, SM | 1 |
| Harbison, RD | 1 |
| Seng, JE | 1 |
| James, RC | 1 |
| Dediu, S | 1 |
1 review available for isoproterenol and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
13 other studies available for isoproterenol and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
The β-adrenoceptor agonist isoproterenol rescues acetaminophen-injured livers through increasing progenitor numbers by Wnt in mice.
Topics: Acetaminophen; Adrenergic beta-Agonists; Analgesics, Non-Narcotic; Animals; Cell Line; Chemical and | 2014 |
The β-adrenoceptor agonist isoproterenol rescues acetaminophen-injured livers: Is it really safe?
Topics: Adrenergic beta-Agonists; Animals; Chemical and Drug Induced Liver Injury; Isoproterenol; Liver; Mal | 2015 |
Reply: To PMID 24923719.
Topics: Adrenergic beta-Agonists; Animals; Chemical and Drug Induced Liver Injury; Isoproterenol; Liver; Mal | 2015 |
Autophagy protects against dasatinib-induced hepatotoxicity via p38 signaling.
Topics: Animals; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; | 2015 |
Contribution of mammalian target of rapamycin in the pathophysiology of cirrhotic cardiomyopathy.
Topics: Action Potentials; Animals; Carbon Tetrachloride; Cardiomyopathies; Cardiotonic Agents; Chemical and | 2016 |
Antioxidant activity of AO-8, a herbal formulation in vitro and in vivo experimental models.
Topics: Animals; Antioxidants; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Free | 1999 |
Potentiation of carbon tetrachloride hepatotoxicity by phenylpropanolamine.
Topics: Animals; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Clonidine; | 1991 |
[Hepatitis caused by drug allergy. (Clinico-morphological study)].
Topics: Aminosalicylic Acids; Chemical and Drug Induced Liver Injury; Chlorpromazine; Drug Hypersensitivity; | 1967 |