isopentenyl pyrophosphate has been researched along with Multiple Myeloma in 3 studies
isopentenyl pyrophosphate: substrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
isopentenyl diphosphate : A prenol phosphate comprising 3-methylbut-3-en-1-ol having an O-diphosphate substituent.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have addressed this issue in multiple myeloma (MM), a prototypic disease with several immune dysfunctions that also affect γδ T cells and DC." | 1.37 | Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells. ( Boccadoro, M; Bosia, A; Canepari, ME; Castella, B; Coscia, M; Fiore, F; Foglietta, M; Massaia, M; Palumbo, A; Pantaleoni, F; Peola, S; Riganti, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashihara, E | 1 |
| Munaka, T | 1 |
| Kimura, S | 1 |
| Nakagawa, S | 1 |
| Nakagawa, Y | 1 |
| Kanai, M | 1 |
| Hirai, H | 1 |
| Abe, H | 1 |
| Miida, T | 1 |
| Yamato, S | 1 |
| Shoji, S | 1 |
| Maekawa, T | 1 |
| Castella, B | 1 |
| Riganti, C | 1 |
| Fiore, F | 1 |
| Pantaleoni, F | 1 |
| Canepari, ME | 1 |
| Peola, S | 1 |
| Foglietta, M | 1 |
| Palumbo, A | 1 |
| Bosia, A | 1 |
| Coscia, M | 1 |
| Boccadoro, M | 1 |
| Massaia, M | 1 |
| Lin, YS | 1 |
| Park, J | 1 |
| De Schutter, JW | 1 |
| Huang, XF | 1 |
| Berghuis, AM | 1 |
| Sebag, M | 1 |
| Tsantrizos, YS | 1 |
3 other studies available for isopentenyl pyrophosphate and Multiple Myeloma
| Article | Year |
|---|---|
Isopentenyl pyrophosphate secreted from Zoledronate-stimulated myeloma cells, activates the chemotaxis of γδT cells.
Topics: Cell Line, Tumor; Chemotaxis, Leukocyte; Culture Media, Conditioned; Diphosphonates; Hemiterpenes; H | 2015 |
Immune modulation by zoledronic acid in human myeloma: an advantageous cross-talk between Vγ9Vδ2 T cells, αβ CD8+ T cells, regulatory T cells, and dendritic cells.
Topics: B7-1 Antigen; Bone Density Conservation Agents; CD8-Positive T-Lymphocytes; Cell Communication; Cell | 2011 |
Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells.
Topics: Aminopyridines; Aniline Compounds; Antineoplastic Agents; Apoptosis; Catalytic Domain; Cell Survival | 2012 |