Page last updated: 2024-10-21

isopentenyl pyrophosphate and Malaria

isopentenyl pyrophosphate has been researched along with Malaria in 7 studies

isopentenyl pyrophosphate: substrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
isopentenyl diphosphate : A prenol phosphate comprising 3-methylbut-3-en-1-ol having an O-diphosphate substituent.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Swift, RP1
Rajaram, K1
Liu, HB1
Dziedzic, A1
Jedlicka, AE1
Roberts, AD1
Matthews, KA1
Jhun, H1
Bumpus, NN1
Tewari, SG1
Wallqvist, A1
Prigge, ST1
Meister, TR1
Tang, Y1
Pulkoski-Gross, MJ1
Yeh, E2
Nair, SC1
Striepen, B1
DeRisi, JL1
Jomaa, H1
Wiesner, J1
Sanderbrand, S1
Altincicek, B1
Weidemeyer, C1
Hintz, M1
Türbachova, I1
Eberl, M1
Zeidler, J1
Lichtenthaler, HK1
Soldati, D1
Beck, E1
Ridley, RG1
Mbaya, B1
Rigomier, D1
Edorh, GG1
Karst, F1
Schrevel, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Comparative Assessment of the Efficacy of Fosmidomycin-Clindamycin Versus Sulfadoxine-Pyrimethamine for the Treatment of Children With Uncomplicated Plasmodium Falciparum Malaria[NCT00214643]Phase 3160 participants Interventional2005-06-30Completed
Evaluation of Fosmidomycin in Combination With Clindamycin in Children With Acute Uncomplicated Plasmodium Falciparum Malaria[NCT00217451]Phase 251 participants Interventional2002-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for isopentenyl pyrophosphate and Malaria

ArticleYear
What do human parasites do with a chloroplast anyway?
    PLoS biology, 2011, Volume: 9, Issue:8

    Topics: Animals; Chloroplasts; Hemiterpenes; Humans; Life Cycle Stages; Malaria; Organophosphorus Compounds;

2011

Other Studies

6 other studies available for isopentenyl pyrophosphate and Malaria

ArticleYear
A mevalonate bypass system facilitates elucidation of plastid biology in malaria parasites.
    PLoS pathogens, 2020, Volume: 16, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Apicoplasts; Azithromycin; Fosfomycin; Hemiterpenes; Humans; Malaria

2020
CaaX-Like Protease of Cyanobacterial Origin Is Required for Complex Plastid Biogenesis in Malaria Parasites.
    mBio, 2020, 10-06, Volume: 11, Issue:5

    Topics: Cyanobacteria; Erythrocytes; Hemiterpenes; Humans; Malaria; Organelle Biogenesis; Organophosphorus C

2020
Chemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparum.
    PLoS biology, 2011, Volume: 9, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Cell Death; Chloroplasts; Fosfomycin; Genome, Protozoan; Hemiterpene

2011
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs.
    Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433

    Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme In

1999
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs.
    Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433

    Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme In

1999
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs.
    Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433

    Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme In

1999
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs.
    Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433

    Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme In

1999
Planting the seeds of new antimalarial drugs.
    Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433

    Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Drug Design; Enzyme Inhibitors; Fosfomycin; Hemite

1999
Isoprenoid metabolism in Plasmodium falciparum during the intraerythrocytic phase of malaria.
    Biochemical and biophysical research communications, 1990, Dec-31, Volume: 173, Issue:3

    Topics: Acetates; Animals; Cells, Cultured; Erythrocytes; Hemiterpenes; Humans; Malaria; Mevalonic Acid; Org

1990