isopentenyl pyrophosphate has been researched along with Malaria, Falciparum in 7 studies
isopentenyl pyrophosphate: substrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
isopentenyl diphosphate : A prenol phosphate comprising 3-methylbut-3-en-1-ol having an O-diphosphate substituent.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sayers, CP | 1 |
| Mollard, V | 1 |
| Buchanan, HD | 1 |
| McFadden, GI | 3 |
| Goodman, CD | 2 |
| Uddin, T | 1 |
| Kennedy, K | 1 |
| Cobbold, SA | 1 |
| Hanssen, E | 1 |
| Birnbaum, J | 1 |
| Spillman, NJ | 1 |
| McHugh, E | 1 |
| Brown, H | 1 |
| Tilley, L | 1 |
| Spielmann, T | 1 |
| McConville, MJ | 1 |
| Ralph, SA | 2 |
| van Dooren, GG | 1 |
| Waller, RF | 1 |
| Crawford, MJ | 1 |
| Fraunholz, MJ | 1 |
| Foth, BJ | 1 |
| Tonkin, CJ | 1 |
| Roos, DS | 1 |
| Jomaa, H | 1 |
| Wiesner, J | 1 |
| Sanderbrand, S | 1 |
| Altincicek, B | 1 |
| Weidemeyer, C | 1 |
| Hintz, M | 1 |
| Türbachova, I | 1 |
| Eberl, M | 1 |
| Zeidler, J | 1 |
| Lichtenthaler, HK | 1 |
| Soldati, D | 1 |
| Beck, E | 1 |
| Ridley, RG | 1 |
| Daubenberger, CA | 1 |
| Salomon, M | 1 |
| Vecino, W | 1 |
| Hübner, B | 1 |
| Troll, H | 1 |
| Rodriques, R | 1 |
| Patarroyo, ME | 1 |
| Pluschke, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparative Assessment of the Efficacy of Fosmidomycin-Clindamycin Versus Sulfadoxine-Pyrimethamine for the Treatment of Children With Uncomplicated Plasmodium Falciparum Malaria[NCT00214643] | Phase 3 | 160 participants | Interventional | 2005-06-30 | Completed | ||
| Evaluation of Fosmidomycin in Combination With Clindamycin in Children With Acute Uncomplicated Plasmodium Falciparum Malaria[NCT00217451] | Phase 2 | 51 participants | Interventional | 2002-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for isopentenyl pyrophosphate and Malaria, Falciparum
| Article | Year |
|---|---|
Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast.
Topics: Animals; Antimalarials; Energy Metabolism; Fatty Acids; Heme; Hemiterpenes; Host-Parasite Interactio | 2004 |
6 other studies available for isopentenyl pyrophosphate and Malaria, Falciparum
| Article | Year |
|---|---|
A genetic screen in rodent malaria parasites identifies five new apicoplast putative membrane transporters, one of which is essential in human malaria parasites.
Topics: Animals; Apicoplasts; Biological Transport; Gene Knockout Techniques; Hemiterpenes; Humans; Malaria, | 2018 |
Validation of Putative Apicoplast-Targeting Drugs Using a Chemical Supplementation Assay in Cultured Human Malaria Parasites.
Topics: Antimalarials; Apicoplasts; Azithromycin; Cells, Cultured; Drug Evaluation, Preclinical; Fatty Acids | 2018 |
Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking.
Topics: Animals; Antimalarials; Apicoplasts; Cell Death; Hemiterpenes; Humans; Intracellular Space; Malaria, | 2019 |
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs.
Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme In | 1999 |
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs.
Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme In | 1999 |
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs.
Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme In | 1999 |
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs.
Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme In | 1999 |
Planting the seeds of new antimalarial drugs.
Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Drug Design; Enzyme Inhibitors; Fosfomycin; Hemite | 1999 |
Functional and structural similarity of V gamma 9V delta 2 T cells in humans and Aotus monkeys, a primate infection model for Plasmodium falciparum malaria.
Topics: Amino Acid Sequence; Animals; Aotidae; Base Sequence; Cells, Cultured; Disease Models, Animal; Gene | 2001 |