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isopentenyl pyrophosphate and Bone Cancer

isopentenyl pyrophosphate has been researched along with Bone Cancer in 2 studies

isopentenyl pyrophosphate: substrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
isopentenyl diphosphate : A prenol phosphate comprising 3-methylbut-3-en-1-ol having an O-diphosphate substituent.

Research Excerpts

ExcerptRelevanceReference
"MDA-MB-231, T47D and MCF-7 breast cancer cells were treated with BP (zoledronic acid, risedronate, ibandronate, alendronate) and the pyrophosphate channel inhibitors probenecid and novobiocin."7.80Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells. ( Auriola, S; Coimbra de Sousa, S; Ebert, R; Graser, S; Hofbauer, LC; Jakob, F; Määttä, J; Meissner-Weigl, J; Mentrup, B; Rachner, TD; Zeck, S, 2014)
"MDA-MB-231, T47D and MCF-7 breast cancer cells were treated with BP (zoledronic acid, risedronate, ibandronate, alendronate) and the pyrophosphate channel inhibitors probenecid and novobiocin."3.80Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells. ( Auriola, S; Coimbra de Sousa, S; Ebert, R; Graser, S; Hofbauer, LC; Jakob, F; Määttä, J; Meissner-Weigl, J; Mentrup, B; Rachner, TD; Zeck, S, 2014)
" However, bisphosphonates exhibit a high affinity for bone mineral, which reduces their bioavailability for tumor cells."1.42Low-intensity continuous ultrasound triggers effective bisphosphonate anticancer activity in breast cancer. ( Clézardin, P; Gineyts, E; Melodelima, D; Ngo, J; Roux, JP; Tardoski, S, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ebert, R1
Meissner-Weigl, J1
Zeck, S1
Määttä, J1
Auriola, S1
Coimbra de Sousa, S1
Mentrup, B1
Graser, S1
Rachner, TD1
Hofbauer, LC1
Jakob, F1
Tardoski, S1
Ngo, J1
Gineyts, E1
Roux, JP1
Clézardin, P1
Melodelima, D1

Other Studies

2 other studies available for isopentenyl pyrophosphate and Bone Cancer

ArticleYear
Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells.
    Molecular cancer, 2014, Dec-11, Volume: 13

    Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Breast Neoplasms; Caspase 3; Caspase 7; Cell Line,

2014
Low-intensity continuous ultrasound triggers effective bisphosphonate anticancer activity in breast cancer.
    Scientific reports, 2015, Nov-18, Volume: 5

    Topics: Animals; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell

2015