isoniazid has been researched along with Weight Gain in 11 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The serum INH concentrations were higher in the undernourished group but the pharmacokinetic parameters were comparable with those in the normal nutrition group." | 6.75 | Pharmacokinetics of isoniazid in moderately malnourished children with tuberculosis. ( Gupta, D; Gupta, P; Mishra, TK; Roy, V; Sethi, GR, 2010) |
| " The serum INH concentrations were higher in the undernourished group but the pharmacokinetic parameters were comparable with those in the normal nutrition group." | 2.75 | Pharmacokinetics of isoniazid in moderately malnourished children with tuberculosis. ( Gupta, D; Gupta, P; Mishra, TK; Roy, V; Sethi, GR, 2010) |
| "Among persons who were underweight at diagnosis, weight gain of 5% or less between diagnosis and completion of 2-mo intensive phase therapy was moderately associated with an increased relapse risk (18." | 2.72 | Lack of weight gain and relapse risk in a large tuberculosis treatment trial. ( Horsburgh, CR; Khan, A; Reves, R; Sterling, TR; Vernon, A, 2006) |
| "Furosemide 20 mg/kg was administered intravenously to rats pretreated with various CYP inducers--3-methylcholanthrene, orphenadrine citrate and isoniazid, inducers of CYP1A1/2, 2B1/2 and 2E1, respectively, in rats--and inhibitors--SKF-525A (a non-specific inhibitor of CYP isozymes), sulfaphenazole, cimetidine, quinine hydrochloride and troleandomycin, inhibitors of CYP2C6, 2C11, 2D and 3A1/2, respectively, in rats." | 1.35 | Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism. ( Choi, YH; Lee, JH; Lee, MG; Lee, U; Yang, KH, 2009) |
| " Although risk-assessment procedures that attempt to utilize the quantitative information in such data have been proposed, there is no general agreement that these procedures are appreciably more efficient than common quantal dose-response procedures that operate on dichotomized continuous data." | 1.30 | A comparison of methods of benchmark-dose estimation for continuous response data. ( Kodell, RL; West, RW, 1999) |
| "Body weight gain was only depressed with the highest level of ISON (405 ppm)." | 1.28 | Effect of feeding isoniazid and cimetidine on growth and bone development in male broiler chicks. ( Jensen, LS; Rowland, GN; Wyatt, CL, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Baraki, AG | 1 |
| Gezie, LD | 1 |
| Zeleke, EG | 1 |
| Awoke, T | 1 |
| Tsegaye, AT | 1 |
| Peetluk, LS | 1 |
| Rebeiro, PF | 1 |
| Cordeiro-Santos, M | 1 |
| Kritski, A | 1 |
| Andrade, BB | 1 |
| Durovni, B | 1 |
| Calvacante, S | 1 |
| Arriaga, MB | 1 |
| Turner, MM | 1 |
| Figueiredo, MC | 1 |
| Rolla, VC | 1 |
| Sterling, TR | 2 |
| Yang, KH | 2 |
| Choi, YH | 1 |
| Lee, U | 1 |
| Lee, JH | 2 |
| Lee, MG | 2 |
| Roy, V | 1 |
| Gupta, D | 1 |
| Gupta, P | 1 |
| Sethi, GR | 1 |
| Mishra, TK | 1 |
| MUDIE, IS | 1 |
| HORNE, NW | 1 |
| CROFTON, JW | 1 |
| Hendrickson, RF | 1 |
| Alvares, AP | 1 |
| Visek, WJ | 1 |
| Khan, A | 1 |
| Reves, R | 1 |
| Vernon, A | 1 |
| Horsburgh, CR | 1 |
| Bosch, RJ | 1 |
| Wypij, D | 1 |
| Ryan, LM | 1 |
| West, RW | 1 |
| Kodell, RL | 1 |
| Wyatt, CL | 1 |
| Jensen, LS | 1 |
| Rowland, GN | 1 |
2 trials available for isoniazid and Weight Gain
| Article | Year |
|---|---|
Pharmacokinetics of isoniazid in moderately malnourished children with tuberculosis.
Topics: Antitubercular Agents; Child; Child Nutrition Disorders; Child, Preschool; Female; Humans; India; Is | 2010 |
Lack of weight gain and relapse risk in a large tuberculosis treatment trial.
Topics: Adult; Antitubercular Agents; Body Mass Index; Body Weight; Female; Humans; Isoniazid; Male; Middle | 2006 |
9 other studies available for isoniazid and Weight Gain
| Article | Year |
|---|---|
Body mass index variation over time and associated factors among HIV-positive adults on second-line ART in north-west Ethiopia: a retrospective follow-up study.
Topics: Adult; Anti-HIV Agents; Anti-Infective Agents; Antiretroviral Therapy, Highly Active; Body Mass Inde | 2019 |
Lack of Weight Gain During the First 2 Months of Treatment and Human Immunodeficiency Virus Independently Predict Unsuccessful Treatment Outcomes in Tuberculosis.
Topics: Adult; Antitubercular Agents; Brazil; Ethambutol; Female; HIV Seropositivity; Humans; Isoniazid; Mal | 2020 |
Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism.
Topics: Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cimetidine; Cytochrome P-450 Enzyme System | 2009 |
Isoniazid and weight gain: a pilot investigation.
Topics: Body Weight; Isoniazid; Niacin; Nicotinic Acids; Tuberculosis; Tuberculosis, Pulmonary; Weight Gain | 1954 |
EFFECTS OF CHLORTETRACYCLINE AND ISONIAZID ON BODY WEIGHT GAIN AND INTESTINAL UREA HYDROLYSIS OF RATS.
Topics: Body Weight; Chlortetracycline; Hydrolysis; Intestines; Isoniazid; Metabolism; Pharmacology; Rats; R | 1964 |
Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU.
Topics: Animals; Area Under Curve; Benz(a)Anthracenes; Chromatography, High Pressure Liquid; Cytochrome P-45 | 2008 |
A semiparametric approach to risk assessment for quantitative outcomes.
Topics: Animals; Environmental Exposure; Environmental Pollutants; Female; Humans; Isoniazid; Models, Statis | 1996 |
A comparison of methods of benchmark-dose estimation for continuous response data.
Topics: Animals; Antitubercular Agents; Benchmarking; Bias; Computer Simulation; Confidence Intervals; Dose- | 1999 |
Effect of feeding isoniazid and cimetidine on growth and bone development in male broiler chicks.
Topics: Animals; Bone Development; Bone Diseases; Calcium; Chickens; Cholecalciferol; Cimetidine; Isoniazid; | 1990 |