Page last updated: 2024-10-29

isoniazid and Wallerian Degeneration

isoniazid has been researched along with Wallerian Degeneration in 2 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Wallerian Degeneration: Degeneration of distal aspects of a nerve axon following injury to the cell body or proximal portion of the axon. The process is characterized by fragmentation of the axon and its MYELIN SHEATH.

Research Excerpts

ExcerptRelevanceReference
"Large single doses if isoniazid by mouth (1--2g/kg) have been shown to produce in rats Wallerian degeneration visible with the light microscope from the third day onwards."3.66Studies on the early changes in acute isoniazid neuropathy in the rat. ( Cavanagh, JB; Jacobs, JM; Miller, RH; Whittle, A, 1979)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colip, MP1
Baughman, S1
Peterson, RG1
Jacobs, JM1
Miller, RH1
Whittle, A1
Cavanagh, JB1

Other Studies

2 other studies available for isoniazid and Wallerian Degeneration

ArticleYear
Alteration of fucose/leucine incorporation into PNS myelin by isoniazid neuropathy.
    Journal of neurobiology, 1981, Volume: 12, Issue:2

    Topics: Animals; Fucose; Isoniazid; Leucine; Male; Myelin Proteins; Peripheral Nervous System Diseases; Rats

1981
Studies on the early changes in acute isoniazid neuropathy in the rat.
    Acta neuropathologica, 1979, Jul-13, Volume: 47, Issue:2

    Topics: Acute Disease; Animals; Axons; Endoplasmic Reticulum; Isoniazid; Microscopy, Electron; Microtubules;

1979