Page last updated: 2024-10-29

isoniazid and Uveitis

isoniazid has been researched along with Uveitis in 27 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Uveitis: Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Sixteen patients with TB-HIV co-infection received rifabutin 300 mg QD in combination with tuberculosis chemotherapy (initially pyrazinamide, isoniazid and ethambutol then only isoniazid), and were then randomized to receive isoniazid and LPV/r based ART with rifabutin 150 mg tiw or rifabutin 150 mg daily."9.19Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy. ( Connolly, C; Harries, A; Kellerman, T; Lienhardt, C; McIlleron, H; Naiker, S; Pym, A; Reddy, T; Wiesner, L, 2014)
"Of 38 cases of uveitis examined from 1970 to 1980 in which a tuberculous cause was considered, we classified 18 as presumed tuberculous on the basis of a positive response to isoniazid."7.66The role of the isoniazid therapeutic test in tuberculous uveitis. ( Abrams, J; Schlaegel, TF, 1982)
"Sixteen patients with TB-HIV co-infection received rifabutin 300 mg QD in combination with tuberculosis chemotherapy (initially pyrazinamide, isoniazid and ethambutol then only isoniazid), and were then randomized to receive isoniazid and LPV/r based ART with rifabutin 150 mg tiw or rifabutin 150 mg daily."5.19Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy. ( Connolly, C; Harries, A; Kellerman, T; Lienhardt, C; McIlleron, H; Naiker, S; Pym, A; Reddy, T; Wiesner, L, 2014)
"Of 38 cases of uveitis examined from 1970 to 1980 in which a tuberculous cause was considered, we classified 18 as presumed tuberculous on the basis of a positive response to isoniazid."3.66The role of the isoniazid therapeutic test in tuberculous uveitis. ( Abrams, J; Schlaegel, TF, 1982)
"Retinal vasculitis was occlusive in six patients (50%)."1.48Review of people with retinal vasculitis and positive QuantiFERON ( Barthelmes, D; Böni, C; Brunner, DR; Meier, F; Zweifel, SA, 2018)
"The uveitis was treated with local and systemic anti-inflammatory and immunosuppressive therapy in all patients."1.48Effect of Antituberculous Therapy on Uveitis Associated With Latent Tuberculosis. ( Leong, BCS; Lightman, S; McCluskey, PJ; Tomkins-Netzer, O; Zhang, X, 2018)
"Papulonecrotic tuberculids represent an immunological expression of an internal focus of tuberculosis in an individual with a moderate or high degree of immunity."1.35Papulonecrotic tuberculids associated with uveitis. ( Awan, S; Dar, NR; Raza, N; Zafar, O, 2008)
"Tuberculosis and syphilis are often missed by ophthalmologists."1.26Bacterial and protozoal uveitis. ( Schlaegel, TF, 1981)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199015 (55.56)18.7374
1990's2 (7.41)18.2507
2000's3 (11.11)29.6817
2010's7 (25.93)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yaghoubi, GH1
Abedi, F1
Ziaee, M1
Norouzpour, A1
Brunner, DR1
Zweifel, SA1
Barthelmes, D1
Meier, F1
Böni, C1
Tomkins-Netzer, O1
Leong, BCS1
Zhang, X1
Lightman, S1
McCluskey, PJ1
Naiker, S1
Connolly, C1
Wiesner, L1
Kellerman, T1
Reddy, T1
Harries, A1
McIlleron, H1
Lienhardt, C1
Pym, A1
Ang, M1
Htoon, HM1
Chee, SP1
Mackensen, F1
Becker, M1
Zimmermann, S1
Basu, S1
Padhi, TR1
Llorenç, V1
González-Martin, J1
Keller, J1
Rey, A1
Pelegrín, L1
Mesquida, M1
Adán, A1
SCHLAEGEL, TF6
HUNGERFORD, LN1
KAERKELAE, A1
MIETTINEN, P1
TUOVINEN, E1
Chirazi, MS1
Dar, NR1
Raza, N1
Zafar, O1
Awan, S1
Arrell, RW1
Abrams, J2
Abbott, CJ1
Kim, JY1
Carroll, CP1
Opremcak, EM1
Gupta, V1
Arora, S1
Gupta, A1
Ram, J1
Bambery, P1
Sehgal, S1
Morimura, Y1
Okada, AA1
Kawahara, S1
Miyamoto, Y1
Kawai, S1
Hirakata, A1
Hida, T1
O'Connor, GR1
Laffers, Z1
Donaldson, RC1
Canaan, SA1
McLean, RB1
Ackerman, LV1
Cernea, P1
Constantin, F1
Freedman, J1
Kay, ML1
Yanoff, M1
Katowitz, JA1
Weber, JC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in the Treatment of Tuberculosis Patient With HIV Infection in South Africa: A Phase II Trial[NCT00640887]Phase 248 participants (Anticipated)Interventional2009-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for isoniazid and Uveitis

ArticleYear
Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy.
    BMC pharmacology & toxicology, 2014, Nov-19, Volume: 15

    Topics: Adult; Anti-HIV Agents; Antibiotics, Antitubercular; Black People; Coinfection; Cross-Over Studies;

2014
Double-blind therapeutic trial of isoniazid in 344 patients with uveitis.
    The British journal of ophthalmology, 1969, Volume: 53, Issue:6

    Topics: Clinical Trials as Topic; Humans; Isoniazid; Placebos; Tuberculin Test; Tuberculosis; Uveitis

1969

Other Studies

25 other studies available for isoniazid and Uveitis

ArticleYear
Tuberculosis: A Cunning Disease Presenting with Endopericarditis-Associated Bilateral Uveitis
    Turkish journal of ophthalmology, 2019, 12-31, Volume: 49, Issue:6

    Topics: Antitubercular Agents; Drug Therapy, Combination; Endocarditis; Ethambutol; Humans; Isoniazid; Male;

2019
Review of people with retinal vasculitis and positive QuantiFERON
    International ophthalmology, 2018, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Antitubercular Agents; Child; Female; Glucocorticoids; Humans; Interferon-gamma R

2018
Effect of Antituberculous Therapy on Uveitis Associated With Latent Tuberculosis.
    American journal of ophthalmology, 2018, Volume: 190

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination;

2018
Diagnosis of tuberculous uveitis: clinical application of an interferon-gamma release assay.
    Ophthalmology, 2009, Volume: 116, Issue:7

    Topics: Adult; Antitubercular Agents; Area Under Curve; Drug Therapy, Combination; Enzyme-Linked Immunosorbe

2009
Tuberculous uveitis.
    Ophthalmology, 2010, Volume: 117, Issue:2

    Topics: Antitubercular Agents; Area Under Curve; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assa

2010
Tuberculous uveitis.
    Ophthalmology, 2010, Volume: 117, Issue:5

    Topics: Antitubercular Agents; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Humans; Interfe

2010
Indirect supportive evidence for diagnosis of tuberculosis-related uveitis: from the tuberculin skin test to the new interferon gamma release assays.
    Acta ophthalmologica, 2013, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Drug Therapy, Combination;

2013
Isoniazid in tuberculous uveitis.
    A.M.A. archives of ophthalmology, 1954, Volume: 51, Issue:4

    Topics: Eye; Isoniazid; Niacin; Nicotinic Acids; Tuberculosis; Tuberculosis, Ocular; Uveitis

1954
COMPARATIVE STUDIES IN ISONIAZID AND ACETYLISONIAZID CONCENTRATIONS IN AQUEOUS HUMOUR AND SERUM.
    Annales medicinae experimentalis et biologiae Fenniae, 1963, Volume: 41

    Topics: Aqueous Humor; Blood Chemical Analysis; Chorioretinitis; Chromatography; Eye; Glaucoma; Humans; Ison

1963
[Tuberculosis of young children with sensory changes. (Report of two cases)].
    Annales de pediatrie, 1976, Feb-02, Volume: 23, Issue:2

    Topics: Aminosalicylic Acid; Antitubercular Agents; Child; Child, Preschool; Drug Therapy, Combination; Faci

1976
Papulonecrotic tuberculids associated with uveitis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2008, Volume: 18, Issue:4

    Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Glucocorticoids; Humans; Isonia

2008
Acute tuberculous panophthalmitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1967, Volume: 78, Issue:1

    Topics: Acetazolamide; Aged; Aminosalicylic Acids; Atropine; Choroid Neoplasms; Exophthalmos; Female; Glauco

1967
The tuberculin skin test in the diagnosis of tuberculous uveitis.
    American journal of ophthalmology, 1983, Volume: 96, Issue:3

    Topics: Adolescent; Adult; Female; Humans; Isoniazid; Male; Middle Aged; Tuberculin Test; Tuberculosis, Ocul

1983
Tuberculous uveitis.
    American journal of ophthalmology, 1983, Volume: 95, Issue:1

    Topics: Humans; Isoniazid; Tuberculosis, Ocular; Uveitis

1983
The role of the isoniazid therapeutic test in tuberculous uveitis.
    American journal of ophthalmology, 1982, Volume: 94, Issue:4

    Topics: Adult; Humans; Isoniazid; Middle Aged; Tuberculin Test; Tuberculosis, Ocular; Uveitis; Uveitis, Ante

1982
Bacterial and protozoal uveitis.
    Transactions of the ophthalmological societies of the United Kingdom, 1981, Volume: 101 (Pt 3), Issue:3

    Topics: Humans; Isoniazid; Serologic Tests; Syphilis; Toxoplasmosis, Ocular; Tuberculin Test; Tuberculosis,

1981
Antibiotic-resistant tuberculous choroiditis.
    American journal of ophthalmology, 1993, Feb-15, Volume: 115, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Choroiditis; Drug Resistance, Microbial; Drug Therapy, Combination; Eth

1993
Management of presumed intraocular tuberculosis: possible role of the polymerase chain reaction.
    Acta ophthalmologica Scandinavica, 1998, Volume: 76, Issue:6

    Topics: Adolescent; Adult; Antibiotics, Antitubercular; Aqueous Humor; Child; DNA Primers; DNA, Bacterial; F

1998
Tuberculin skin testing in uveitis patients and treatment of presumed intraocular tuberculosis in Japan.
    Ophthalmology, 2002, Volume: 109, Issue:5

    Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Female; Fluorescein Angiography; Fundus Ocu

2002
Metastatic nonsuppurative uveitis.
    International ophthalmology clinics, 1977,Fall, Volume: 17, Issue:3

    Topics: Choroiditis; Endophthalmitis; Humans; Isoniazid; Leprosy; Pigment Epithelium of Eye; Syphilis; Syphi

1977
[Complete destruction of the orbit by a malignant tumor (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1974, Volume: 165, Issue:3

    Topics: Cortisone; Diagnostic Errors; Dihydrostreptomycin Sulfate; Eye, Artificial; Female; Humans; Isoniazi

1974
Uveitis and vitiligo associated with BCG treatment for malignant melanoma.
    Surgery, 1974, Volume: 76, Issue:5

    Topics: Adult; Aged; Axilla; BCG Vaccine; Drug Therapy, Combination; Female; Humans; Injections, Intradermal

1974
[Clinical features of tuberculosis of the optic disc (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1974, Volume: 165, Issue:3

    Topics: Adult; Aminosalicylic Acids; Atrophy; Chorioretinitis; Ethionamide; Female; Humans; Isoniazid; Middl

1974
Anterior uveitis in Bantu children.
    The British journal of ophthalmology, 1973, Volume: 57, Issue:5

    Topics: Adolescent; Black or African American; Black People; Cataract; Cataract Extraction; Child; Child, Pr

1973
Development of sympathetic uveitis in spite of corticosteroid therapy.
    American journal of ophthalmology, 1974, Volume: 78, Issue:1

    Topics: Ampicillin; Choroid; Eye Injuries; Humans; Isoniazid; Male; Middle Aged; Ophthalmia, Sympathetic; Pr

1974