isoniazid has been researched along with Thalassemia in 4 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| TRUMAN, JT | 1 |
| TALBOT, NB | 1 |
| Brittenham, GM | 1 |
| Chalevelakis, G | 1 |
| Yalouris, AG | 1 |
| Lyberatos, C | 1 |
| Economopoulos, T | 1 |
| Anastasiou, C | 1 |
| Hatziioannou, J | 1 |
| Raptis, S | 1 |
| Sullivan, AL | 1 |
| Weintraub, LR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Chelation Therapy of Iron Overload With Oral Pyridoxal Isonicotinoyl Hydrazone[NCT00000588] | Phase 2 | 120 participants (Actual) | Interventional | 1989-06-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for isoniazid and Thalassemia
| Article | Year |
|---|---|
Pyridoxal isonicotinoyl hydrazone. Effective iron chelation after oral administration.
Topics: Administration, Oral; Animals; Drug Evaluation; Humans; Iron Chelating Agents; Isoniazid; Pyridoxal; | 1990 |
Sideroblastic anemias. An approach to diagnosis and management.
Topics: Alcoholism; Anemia, Sideroblastic; Erythrocytes, Abnormal; Female; Folic Acid Deficiency; Genes; Hem | 1973 |
1 trial available for isoniazid and Thalassemia
| Article | Year |
|---|---|
Pyridoxal isonicotinoyl hydrazone. Effective iron chelation after oral administration.
Topics: Administration, Oral; Animals; Drug Evaluation; Humans; Iron Chelating Agents; Isoniazid; Pyridoxal; | 1990 |
2 other studies available for isoniazid and Thalassemia
| Article | Year |
|---|---|
ANEMIA IN CHILDHOOD.
Topics: Anemia; Anemia, Aplastic; Child; Chloramphenicol; Classification; Diagnosis, Differential; Erythrocy | 1964 |
Effect of isoniazid, a haem inhibitor, on globin chain synthesis in reticulocytes from non-thalassaemic and beta thalassaemic subjects.
Topics: Adult; Female; Globins; Hemin; Humans; Isoniazid; Male; Middle Aged; Reticulocytes; Thalassemia | 1989 |