isoniazid has been researched along with Status Epilepticus in 14 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoniazid (INH) is an effective treatment for tuberculosis and among the most common causes of drug-induced seizures in the United States." | 5.36 | Isoniazid-induced status epilepticus in a pediatric patient after inadequate pyridoxine therapy. ( Clark, RF; Ghafouri, N; Minns, AB, 2010) |
| "Isoniazid (INH) is an integral component of treatment of tuberculosis." | 5.35 | Isoniazid toxicity presenting as status epilepticus and severe metabolic acidosis. ( Gokhale, YA; Mehta, AD; Rathod, NN; Vaidya, MS, 2009) |
| "A 25-year-old, 54-kg Hispanic man who had recently started multidrug therapy for pulmonary tuberculosis presented in status epilepticus after ingesting 9 g of isoniazid in a suicide attempt." | 3.73 | Acute isoniazid toxicity and the need for adequate pyridoxine supplies. ( Malesker, M; Morrow, LE; Schuller, D; Wear, RE, 2006) |
| "Seizures are commonly encountered in patients who do not have epilepsy." | 2.40 | Medical causes of seizures. ( Delanty, N; French, JA; Vaughan, CJ, 1998) |
| "Isoniazid (INH) is an effective treatment for tuberculosis and among the most common causes of drug-induced seizures in the United States." | 1.36 | Isoniazid-induced status epilepticus in a pediatric patient after inadequate pyridoxine therapy. ( Clark, RF; Ghafouri, N; Minns, AB, 2010) |
| "Isoniazid (INH) is an integral component of treatment of tuberculosis." | 1.35 | Isoniazid toxicity presenting as status epilepticus and severe metabolic acidosis. ( Gokhale, YA; Mehta, AD; Rathod, NN; Vaidya, MS, 2009) |
| "Isoniazid (INH) is the cause of one of the most common serious drug overdoses and can cause severe metabolic acidosis." | 1.27 | Profound acidosis caused by isoniazid ingestion. ( Faville, RJ; Hankins, DG; Saxena, K; Warren, BJ, 1987) |
| "Each had an obvious cause for repeated seizures." | 1.26 | Postictal pleocytosis. ( Schmidley, JW; Simon, RP, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gokhale, YA | 1 |
| Vaidya, MS | 1 |
| Mehta, AD | 1 |
| Rathod, NN | 1 |
| Minns, AB | 1 |
| Ghafouri, N | 1 |
| Clark, RF | 1 |
| Zell-Kanter, M | 1 |
| Osterhoudt, KC | 1 |
| Henretig, FM | 1 |
| Caksen, H | 1 |
| Odabas, D | 1 |
| Erol, M | 1 |
| Anlar, O | 1 |
| Tuncer, O | 1 |
| Atas, B | 1 |
| Tibussek, D | 1 |
| Mayatepek, E | 1 |
| Distelmaier, F | 1 |
| Rosenbaum, T | 1 |
| Morrow, LE | 1 |
| Wear, RE | 1 |
| Schuller, D | 1 |
| Malesker, M | 1 |
| Schmidley, JW | 1 |
| Simon, RP | 1 |
| Nixon, GM | 1 |
| Stanley, TV | 1 |
| Nelson, LS | 1 |
| Rella, J | 1 |
| Hoffman, RS | 1 |
| Delanty, N | 1 |
| Vaughan, CJ | 1 |
| French, JA | 1 |
| Dixon, AC | 1 |
| Shikuma, L | 1 |
| Duvauchelle, DA | 1 |
| Rappaport, DS | 1 |
| Nakamura, JW | 1 |
| Dippenaar, J | 1 |
| Jameson, C | 1 |
| Dowse, R | 1 |
| Hankins, DG | 1 |
| Saxena, K | 1 |
| Faville, RJ | 1 |
| Warren, BJ | 1 |
1 review available for isoniazid and Status Epilepticus
| Article | Year |
|---|---|
Medical causes of seizures.
Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Blood Pressure; Brain Diseases; Broncho | 1998 |
13 other studies available for isoniazid and Status Epilepticus
| Article | Year |
|---|---|
Isoniazid toxicity presenting as status epilepticus and severe metabolic acidosis.
Topics: Acidosis; Adult; Antitubercular Agents; Bicarbonates; Buffers; Diuretics, Osmotic; Female; Humans; I | 2009 |
Isoniazid-induced status epilepticus in a pediatric patient after inadequate pyridoxine therapy.
Topics: Antitubercular Agents; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Overdose; Hum | 2010 |
Oral pyridoxine in the management of isoniazid poisoning.
Topics: Administration, Oral; Antidotes; Humans; Intubation, Gastrointestinal; Isoniazid; Pyridoxine; Status | 2010 |
A 16-year-old with recalcitrant seizures.
Topics: Acidosis; Adolescent; Antitubercular Agents; Female; Humans; Isoniazid; Status Epilepticus | 2012 |
Do not overlook acute isoniazid poisoning in children with status epilepticus.
Topics: Acidosis; Antitubercular Agents; Child, Preschool; Diagnosis, Differential; Diazepam; Drug Overdose; | 2003 |
Status epilepticus due to attempted suicide with isoniazid.
Topics: Antitubercular Agents; Child; Drug Overdose; Female; Humans; Isoniazid; Status Epilepticus; Suicide, | 2006 |
Acute isoniazid toxicity and the need for adequate pyridoxine supplies.
Topics: Acute Disease; Adult; Antidotes; Antitubercular Agents; Drug Overdose; Drugs, Essential; Humans; Inf | 2006 |
Postictal pleocytosis.
Topics: Adult; Blood-Brain Barrier; Cerebrospinal Fluid; Female; Humans; Isoniazid; Male; Middle Aged; Seizu | 1981 |
Status epilepticus due to accidental overdose of isoniazid in an infant.
Topics: Drug Overdose; Female; Humans; Infant; Isoniazid; Status Epilepticus; Tuberculosis | 1996 |
Status epilepticus.
Topics: Drug Overdose; Humans; Isoniazid; Pyridoxine; Status Epilepticus | 1998 |
Isoniazid overdose: a case report.
Topics: Adult; Half-Life; Humans; Isoniazid; Male; Status Epilepticus | 1988 |
Side effects of isoniazid.
Topics: Female; Humans; Isoniazid; Middle Aged; Status Epilepticus | 1987 |
Profound acidosis caused by isoniazid ingestion.
Topics: Acidosis, Lactic; Adolescent; Humans; Hydrogen-Ion Concentration; Isoniazid; Male; Poisoning; Status | 1987 |