isoniazid and Skin Diseases studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Research Excerpts

Excerpt	Relevance	Reference
"Ethionamide is a structural analogue of isoniazid and the two drugs share other similarities, including their metabolism, therapeutic targets, hepato-toxicity patterns and drug resistance."	2.80	Lack of cross-toxicity between isoniazid and ethionamide in severe cutaneous adverse drug reactions: a series of 25 consecutive confirmed cases. ( Dheda, K; Dlamini, S; Gantsho, N; Lehloenya, RJ; Muloiwa, R; Todd, G, 2015)
"To study the frequency and degree of adverse effect, other than liver dysfunction, of isoniazid (INH) preventive therapy in Japanese people."	1.34	[Adverse effect other than liver dysfunction in treatment of latent tuberculous infection by isoniazid]. ( Hoshino, H; Ito, K; Kato, S; Masuyama, H; Nakazono, T; Sugita, H; Yoshiyama, T, 2007)
" Major toxic effects occurred in 22 patients; in 14 during the daily phase and in 8 during the twice-weekly phase."	1.27	Undesirable side effects of isoniazid and rifampin in largely twice-weekly short-course chemotherapy for tuberculosis. ( Dutt, AK; Moers, D; Stead, WW, 1983)

Timeframe	Studies, this research(%)	All Research%
pre-1990	46 (88.46)	18.7374
1990's	1 (1.92)	18.2507
2000's	2 (3.85)	29.6817
2010's	2 (3.85)	24.3611
2020's	1 (1.92)	2.80

Authors	Studies
Kigawa, T	1
Kawai, M	1
Yamaoka, H	1
Kondoh, A	1
Tojo, M	1
Mabuchi, T	1
Lehloenya, RJ	1
Muloiwa, R	1
Dlamini, S	1
Gantsho, N	1
Todd, G	1
Dheda, K	1
Usui, T	1
Meng, X	1
Saide, K	1
Farrell, J	1
Thomson, P	1
Whitaker, P	1
Watson, J	1
French, NS	1
Kevin Park, B	1
Naisbitt, DJ	1
Marzano, AV	1
Vezzoli, P	1
Crosti, C	1
LEIDER, M	1
SAWICKY, HH	1
COTTINI, GB	1
PISACANE, C	1
CORMIA, FE	1
COSTELLO, MJ	1
BARKER, LP	1
NELSON, CT	1
WILSON, EW	1
CRAMER, JA	1
GOLDBERG, LC	1
SIMON, CR	1
OBERSTE-LEHN, H	1
RADENBACH, KL	2
ROSENOW, H	2
EISENBLATTER, J	2
NOUSSITOU, F	1
SEOANE, M	1
MOSTO, A	1
WEISS, HJ	1
DIETEL, H	1
SILVERSTRI, U	1
SAPUPPO, A	2
BECKER, SW	2
MOUNCE, SH	2
MELAMED, AJ	1
DI LAURO, E	1
HELFMAN, RJ	1
AMANN, W	1
PROSSER, M	1
HEKELE, K	1
Ito, K	1
Hoshino, H	1
Nakazono, T	1
Masuyama, H	1
Sugita, H	1
Yoshiyama, T	1
Kato, S	1
Cott, RE	1
Carter, DM	1
Sall, T	1
Park, RK	1
Goltz, RW	1
Carey, TB	1
Dutt, AK	1
Moers, D	1
Stead, WW	1
Padmini, R	1
Srinivasan, S	1
Nalini, P	1
Mahadevan, S	1
Rossouw, JE	1
Saunders, SJ	1
Smith, NP	1
Ryan, TJ	1
Sanderson, KV	1
Sarkany, I	1
Holdiness, MR	1
Machtey, I	1
Bandmann, M	1
Palant, A	1
Bureau, Y	1
Barriere, H	1
Bureau, L	1
Litoux, P	1
Falcone, MW	1
Garagusi, VF	1
Cuni, LJ	1
Grünwald, H	1
Rosner, F	1
Degos, R	1
Lortat-Jacob, E	1
Belaïch, S	1
Bonvalet, D	1
Lebrun, J	1
Simon, HB	1
Wolff, SM	1
Javadpour, N	1
Shah, MS	1
Farivari, A	1
Sadoughi, N	1
Fisher, DA	1
Lyss, RS	1
Shaposhnikov, OK	1
Krupko, MI	1
Harmon, R	1
Peterson, P	1
Abello, VB	1
Riley, HD	1
Rubio, T	1
Bazex, A	1
Dupré, A	1
Parant, M	1
Christol, B	1
Cantala, P	1
Kopf, AW	1
Sibulkin, D	1
Blair, AW	1
Lèques, B	1
Bordas, J	1
Pellegrin, J	1
Chenu, V	1
Höfer, W	2
Ache, D	1
Höneann, W	1
Nauwald, G	1

Article	Year
Drug-induced lupus: an update on its dermatologic aspects. Lupus, 2009, Volume: 18, Issue:11 Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antihypertensive Agents; Antitubercular Agents; Autoa	2009
Adverse cutaneous reactions to antituberculosis drugs. International journal of dermatology, 1985, Volume: 24, Issue:5 Topics: Acne Vulgaris; Adult; Amikacin; Antitubercular Agents; Drug Hypersensitivity; Ethambutol; Ethionamid	1985

Article	Year
Lack of cross-toxicity between isoniazid and ethionamide in severe cutaneous adverse drug reactions: a series of 25 consecutive confirmed cases. The Journal of antimicrobial chemotherapy, 2015, Volume: 70, Issue:9 Topics: Adolescent; Adult; Antitubercular Agents; Drug Interactions; Drug-Related Side Effects and Adverse R	2015
A controlled clinical trial of the role of thiacetazone-containing regimens in the treatment of pulmonary tuberculosis in Singapore. Singapore Tuberculosis Services-Brompton Hospital-British Medical Research Council Investigation. Tubercle, 1971, Volume: 52, Issue:2 Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Resistance, Microbial; Female; Humans; Isoniazid;	1971
Co-operative controlled trial of a standard regimen of streptomycin, PAS and isoniazid and three alternative regimens of chemotherapy in Britain. A report from the British Medical Research Council. Tubercle, 1973, Volume: 54, Issue:2 Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Chemical and Drug Induced Liver Injury; Clinical Tria	1973

Article	Year
Two Cases of Subcutaneous Tuberculous Granuloma Associated with BCG Vaccination. The Tokai journal of experimental and clinical medicine, 2020, Sep-20, Volume: 45, Issue:3 Topics: Antitubercular Agents; BCG Vaccine; Female; Granuloma; Humans; Infant; Isoniazid; Male; Skin Disease	2020
From the Cover: Characterization of Isoniazid-Specific T-Cell Clones in Patients with anti-Tuberculosis Drug-Related Liver and Skin Injury. Toxicological sciences : an official journal of the Society of Toxicology, 2017, Volume: 155, Issue:2 Topics: Adolescent; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Clone Cells; Female	2017
Therapeutic assays of the Skin and Cancer Unit of the New York University Hospital. VIII. Isonicotinylhydrazine (rimifon) in the treatment of tuberculosis cutis, some other granulomatous processes and miscellaneous dermatoses of doubtful cause. The Journal of investigative dermatology, 1953, Volume: 21, Issue:1 Topics: Hospitals, University; Isoniazid; Neoplasms; New York; Niacin; Nicotinic Acids; Skin Diseases; Tuber	1953
[Use of isonicotinic acid hydrazide in tuberculous and non tuberculous dermatoses]. Minerva dermatologica, 1953, Volume: 28, Issue:5 Topics: Isoniazid; Niacin; Nicotinic Acids; Skin Diseases; Tuberculosis; Tuberculosis, Cutaneous	1953
[Isonicotinic acid hydrazide in field of dermatology; early results]. Minerva dermatologica, 1953, Volume: 28, Issue:5 Topics: Dermatology; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Skin Diseases	1953
Isoniazid (nydrazid) in treatment of cutaneous diseases; Cutaneous tuberculosis, leprosy, sarcoidosis, and miscellaneous dermatoses. A.M.A. archives of dermatology and syphilology, 1953, Volume: 68, Issue:5 Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids; Sarcoidosis; Skin Diseases; Tuberculosis; Tuberculosis,	1953
Isoniazid therapy of chronic dermatoses. A.M.A. archives of dermatology and syphilology, 1953, Volume: 68, Issue:5 Topics: Chronic Disease; Isoniazid; Niacin; Nicotinic Acids; Skin Diseases	1953
[Experimental studies on the effect of isonicotinic acid hydrazide on hyaluronic acid-hyaluronidase system in mesenchyma]. Klinische Wochenschrift, 1954, Jan-15, Volume: 32, Issue:3-4 Topics: Humans; Hyaluronic Acid; Hyaluronoglucosaminidase; Isoniazid; Mesoderm; Niacin; Nicotinic Acids; Ski	1954
[Striae cutis atrophicae in connection with endocrine disorders in the treatment of tuberculosis with isonicotinic acid hydrazide; clinical aspects and pathogenesis. I]. Medizinische Monatsschrift, 1954, Volume: 8, Issue:1 Topics: Endocrine System Diseases; Isoniazid; Niacin; Nicotinic Acids; Skin Diseases; Tuberculosis; Tubercul	1954
[Therapeutic trial of isoniazid in various dermatoses; preliminary report]. Prensa medica argentina, 1954, Mar-05, Volume: 41, Issue:10 Topics: Isomerism; Isoniazid; Niacin; Nicotinic Acids; Skin Diseases	1954
[Striae cutis atrophicae in connection with endocrine disorders in the treatment of tuberculosis with isoniazid; clinical aspects and pathogenesis. II..]. Medizinische Monatsschrift, 1954, Volume: 8, Issue:2 Topics: Endocrine System Diseases; Isoniazid; Niacin; Nicotinic Acids; Skin Diseases; Tuberculosis; Tubercul	1954
[Interesting clinical and roentgenological observations on INH therapy (rimifon, bacillin)]. Therapie der Gegenwart, 1954, Volume: 93, Issue:3 Topics: Dipeptides; Hemorrhagic Disorders; Isoniazid; Niacin; Nicotinic Acids; Skin Diseases	1954
[Toxicoderma after administration of isoniazid]. Dermatologische Wochenschrift, 1954, Volume: 129, Issue:25 Topics: Drug Eruptions; Immune System Diseases; Isoniazid; Niacin; Nicotinic Acids; Skin Diseases	1954
[The use of isoniazid in the treatment of skin affections. I. Review of literature]. Archivio italiano di dermatologia, sifilografia, e venereologia, 1955, Volume: 27, Issue:4 Topics: Isoniazid; Niacin; Nicotinic Acids; Skin; Skin Diseases	1955
[Clinical aspects of the treatment of some dermatoses with the isopropyl derivative of isoniazid; preliminary report]. Minerva dermatologica, 1956, Volume: 31, Issue:11 Topics: Humans; Isoniazid; Skin Diseases	1956
[Clinical aspects of the treatment of some dermatoses with the isopropyl derivative of isoniazid; preliminary report]. Minerva dermatologica, 1956, Volume: 31, Issue:11 Topics: Humans; Isoniazid; Skin Diseases	1956
[Clinical aspects of the treatment of some dermatoses with the isopropyl derivative of isoniazid; preliminary report]. Minerva dermatologica, 1956, Volume: 31, Issue:11 Topics: Humans; Isoniazid; Skin Diseases	1956
[Clinical aspects of the treatment of some dermatoses with the isopropyl derivative of isoniazid; preliminary report]. Minerva dermatologica, 1956, Volume: 31, Issue:11 Topics: Humans; Isoniazid; Skin Diseases	1956
Dermatoses in patients receiving chemotherapy for systemic tuberculosis. A.M.A. archives of dermatology, 1957, Volume: 75, Issue:3 Topics: Drug Eruptions; Humans; Isoniazid; Skin Diseases; Streptomycin; Tuberculosis	1957
Dermatoses in patients receiving chemotherapy for systemic tuberculosis. A.M.A. archives of dermatology, 1957, Volume: 75, Issue:3 Topics: Drug Eruptions; Humans; Isoniazid; Skin Diseases; Streptomycin; Tuberculosis	1957
Dermatoses in patients receiving chemotherapy for systemic tuberculosis. A.M.A. archives of dermatology, 1957, Volume: 75, Issue:3 Topics: Drug Eruptions; Humans; Isoniazid; Skin Diseases; Streptomycin; Tuberculosis	1957
Dermatoses in patients receiving chemotherapy for systemic tuberculosis. A.M.A. archives of dermatology, 1957, Volume: 75, Issue:3 Topics: Drug Eruptions; Humans; Isoniazid; Skin Diseases; Streptomycin; Tuberculosis	1957
[Cortisone-life effects of isoniazid in dermatology]. El Dia medico, 1957, Oct-17, Volume: 29, Issue:74 Topics: Cortisone; Dermatology; Isoniazid; Life; Skin Diseases; Skin Physiological Phenomena	1957
[Treatment of nasal ozena with isonicotinic acid hydrazide; tuberculous etiopathogenesis of ozena]. La Riforma medica, 1957, Oct-05, Volume: 71, Issue:40 Topics: Atrophy; Humans; Isoniazid; Nose; Rhinitis; Rhinitis, Atrophic; Skin Diseases; Tuberculosis	1957
TOXIC EPIDERMAL NECROLYSIS. Southern medical journal, 1964, Volume: 57 Topics: Amobarbital; Conjunctivitis; Drug Therapy; Humans; Isoniazid; Kanamycin; Phenytoin; Skin Diseases; S	1964
[CAN ACNEIFORM SKIN LESIONS CAUSED BY INH-MEDICATION BE CONSIDERED AS BEING WITHIN THE CONCEPT OF ACNE VULGARIS?]. Dermatologische Wochenschrift, 1964, Dec-19, Volume: 150 Topics: Acne Vulgaris; Humans; Isoniazid; Skin Diseases; Toxicology	1964
[The use of isonicotinic acid hydrazide in skin tuberculosis and other skin diseases]. Zeitschrift fur Haut- und Geschlechtskrankheiten, 1954, Aug-28, Volume: 17, Issue:5 Topics: Isoniazid; Niacin; Nicotinic Acids; Skin Diseases; Tuberculosis; Tuberculosis, Cutaneous	1954
[Adverse effect other than liver dysfunction in treatment of latent tuberculous infection by isoniazid]. Kekkaku : [Tuberculosis], 2007, Volume: 82, Issue:1 Topics: Adolescent; Adult; Antitubercular Agents; Central Nervous System Diseases; Chemical and Drug Induced	2007
Cutaneous disease caused by atypical Mycobacteria. Report of two chromogen infections and review of the subject. Archives of dermatology, 1967, Volume: 95, Issue:3 Topics: Adolescent; Adult; Aminosalicylic Acids; Female; Humans; Isoniazid; Male; Mycobacterium; Mycobacteri	1967
Unusual cutaneous infections associated with immunosuppressive therapy. Archives of dermatology, 1967, Volume: 95, Issue:4 Topics: Adolescent; Adult; Azathioprine; Chickenpox; Child; Female; Herpes Simplex; Histoplasmosis; Humans;	1967
Undesirable side effects of isoniazid and rifampin in largely twice-weekly short-course chemotherapy for tuberculosis. The American review of respiratory disease, 1983, Volume: 128, Issue:3 Topics: Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Female;	1983
Short course chemotherapy for tuberculosis in children. Journal of tropical pediatrics, 1993, Volume: 39, Issue:6 Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Dose-Response Relations	1993
Hepatic complications of antituberculous therapy. The Quarterly journal of medicine, 1975, Volume: 44, Issue:173 Topics: Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Hypersensi	1975
Lichen scrofulosorum. A report of four cases. The British journal of dermatology, 1976, Volume: 94, Issue:3 Topics: Adolescent; Adult; Aged; Female; Humans; Isoniazid; Lymph Nodes; Male; Middle Aged; Skin; Skin Disea	1976
Unusual reaction to B.C.G. Lancet (London, England), 1968, Jan-20, Volume: 1, Issue:7534 Topics: Adolescent; Aminosalicylic Acids; BCG Vaccine; Drug Hypersensitivity; Humans; Isoniazid; Joint Disea	1968
[Reticulo-histiocytoma or multinodular giant cell histiocytosis]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1966, Volume: 17, Issue:1 Topics: Biopsy; Diagnosis, Differential; Histiocytoma, Benign Fibrous; Humans; Isoniazid; Male; Middle Aged;	1966
Sporotrichosis and nocardiosis in a patient with Boeck's sarcoid. Southern medical journal, 1969, Volume: 62, Issue:3 Topics: Adult; Amphotericin B; Bacteriological Techniques; Biopsy; Brain Abscess; Cerebrospinal Fluid Protei	1969
Bullous pemphigoid in chronic lymphocytic leukemia with the demonstration of antibasement membrane antibodies. The American journal of medicine, 1974, Volume: 57, Issue:6 Topics: Autoantibodies; Basement Membrane; Bilirubin; Biopsy; Blood Glucose; Blood Urea Nitrogen; Chlorambuc	1974
[Besnier-Boeck-Schaumann disease (soft tissues and eyelids)]. Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1972, Volume: 79, Issue:3 Topics: Adult; Eyelid Diseases; Fingers; Humans; Isoniazid; Male; Sarcoidosis; Skin Diseases; Syndrome; Tube	1972
Granulomatous hepatitis and prolonged fever of unknown origin: a study of 13 patients. Medicine, 1973, Volume: 52, Issue:1 Topics: Adult; Ascites; Dexamethasone; Edema; Female; Fever; Fever of Unknown Origin; Granuloma; Hepatitis;	1973
Ureter in renal tuberculosis. Urology, 1973, Volume: 2, Issue:3 Topics: Aminosalicylic Acids; Debridement; Dietary Proteins; Drainage; Fistula; Humans; Isoniazid; Male; Mid	1973
Letter: Mycobacterium marinum infection. Archives of dermatology, 1974, Volume: 109, Issue:4 Topics: Adult; Arm; Ethambutol; Granuloma; Hand; Humans; Isoniazid; Male; Mycobacterium Infections; Skin Dis	1974
[Selection of method of treating patients with different forms of sarcoidosis]. Vestnik dermatologii i venerologii, 1972, Volume: 46, Issue:4 Topics: Adrenal Cortex Hormones; Adult; Aged; Female; Humans; Isoniazid; Male; Middle Aged; Sarcoidosis; Ski	1972
Cutaneous sarcoidosis with hypopigmentation and asthma. Rocky Mountain medical journal, 1972, Volume: 69, Issue:10 Topics: Adult; Asthma; Humans; Isoniazid; Male; Pigmentation Disorders; Prednisone; Sarcoidosis; Skin Diseas	1972
Atypical mycobacterial infections in children. Scandinavian journal of infectious diseases, 1971, Volume: 3, Issue:2 Topics: Adolescent; Aminosalicylic Acids; Antigens; Biopsy; Child; Child, Preschool; Female; Gastric Juice;	1971
[Atrophying Besnier-Boeck-Schaumann disease of Pick-Herxheimer type]. Annales de dermatologie et de syphiligraphie, 1971, Volume: 98, Issue:4 Topics: Adult; Cortisone; Humans; Isoniazid; Male; Middle Aged; Sarcoidosis; Skin; Skin Diseases	1971
Paratuberculosis cutis caused by Mycobacterium marinum. Archives of dermatology, 1971, Volume: 104, Issue:4 Topics: Adult; Animals; Humans; Isoniazid; Male; Mycobacterium; Paratuberculosis; Pyridoxine; Skin Diseases;	1971
Indolent non-caseating Mycobacterial tuberculosis. Archives of disease in childhood, 1967, Volume: 42, Issue:223 Topics: Aminosalicylic Acids; Child, Preschool; Diagnosis, Differential; Female; Humans; Isoniazid; Male; Ra	1967
[Purple weals due to rimifon]. Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1970, Volume: 77, Issue:1 Topics: Adrenocortical Hyperfunction; Adult; Humans; Isoniazid; Male; Skin Diseases; Tuberculosis, Pulmonary	1970
Hazard from the home aquarium. British medical journal, 1970, May-23, Volume: 1, Issue:5707 Topics: Aminosalicylic Acids; Animals; Disease Vectors; Female; Fishes; Humans; Isoniazid; Male; Mycobacteri	1970
[Striae cutis atrophica following INH medication]. Zeitschrift fur Haut- und Geschlechtskrankheiten, 1967, Aug-01, Volume: 42, Issue:15 Topics: Adult; Atrophy; Connective Tissue; Female; Humans; Isoniazid; Skin Diseases; Tuberculosis, Pulmonary	1967
[Peutz-Jeghers syndrome with lichenoid tuberculid]. Dermatologische Wochenschrift, 1967, Dec-09, Volume: 153, Issue:49 Topics: Cholangiography; Female; Humans; Intestinal Diseases; Isoniazid; Middle Aged; Peutz-Jeghers Syndrome	1967
[Complications in the course of tuberculous spondylitis]. Archiv fur orthopadische und Unfall-Chirurgie, 1966, Volume: 60, Issue:4 Topics: Cardiovascular Diseases; Central Nervous System Diseases; Female; Gallbladder Diseases; Gastrointest	1966

isoniazid and Skin Diseases

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