Page last updated: 2024-10-29

isoniazid and Pulmonary Fibrosis

isoniazid has been researched along with Pulmonary Fibrosis in 31 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.

Research Excerpts

ExcerptRelevanceReference
" The Author concludes the paper, affirming that chemoprophylaxis with isoniazid, after 20 years of application, has obtained the official chrism and can furnish, besides the BCG vaccine, a remarkable contribution to the control of tuberculosis in all countries of the world."3.66[Antitubercular chemoprophylaxis after 20 years of its world-wide application]. ( Zorini, AO, 1979)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199024 (77.42)18.7374
1990's3 (9.68)18.2507
2000's0 (0.00)29.6817
2010's3 (9.68)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Kim, LB1
Putyatina, AN1
Russkikh, GS1
Shkurupy, VA1
Chung, CU1
Park, DI1
Lee, CS1
Jung, SS1
Dulgar, O1
Eskazan, AE1
Ersen, E1
Demiroz, AS1
Turna, A1
Oz, B1
Tuzuner, N1
Subbian, S1
Tsenova, L1
O'Brien, P1
Yang, G1
Koo, MS1
Peixoto, B1
Fallows, D1
Zeldis, JB1
Muller, G1
Kaplan, G1
ZAIDI, SH1
HARRISON, CV1
KING, EJ1
MITCHISON, DA1
CORPE, RF1
Larizza, P1
Comstock, GW1
Chwalibóg, B2
Petrunina, MP1
Pashkova, IN1
Cárdenas Rodríguez, M1
Pérez Gómez, P1
Lozano Mera, L1
Krebs, A3
Zorini, AO1
Gardiner, TH1
McAnalley, BH1
Heaton, J1
Reynolds, RC1
Salomaa, ER1
Ruokonen, EL1
Tevola, K1
Tala, E1
Andrzheiuk, NI1
Smirnova, NA1
Narovlianskaia, SE1
Novoselova, VP1
Kruglova, EG1
Miyai, M2
Tsubota, T2
Asano, K2
Voog, R1
Couderc, P1
Martin, H1
Pecher, Y1
Perdrix, A1
Grubier, M1
Dankova, D3
Andrews, RH1
Edwards, TA1
Davies, D1
Gacad, G1
Massaro, D1
Stýblo, K1
Reil, I1
Krivánek, J1
Olsen, GN1
Swenson, EW1
Steinbrück, P1
Edwards, LB1
Doster, B1
Livesay, VT1
Grzybowski, S1
Fishaut, H1
Rowe, J1
Brown, A1
DeRemee, RA1

Trials

5 trials available for isoniazid and Pulmonary Fibrosis

ArticleYear
New data on preventive treatment with isoniazid.
    Annals of internal medicine, 1983, Volume: 98, Issue:5 Pt 1

    Topics: Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Drug Administration Schedule; Huma

1983
[Preventive use of INH in patients with pulmonary fibrosis. Part I. Objectives, methods, material, patient acceptance and the tolerance of the treatment].
    Pneumonologia polska, 1980, Volume: 48, Issue:9

    Topics: Adult; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Humans; Isoniazid; Male; Metho

1980
[Preventive use of INH in patients with pulmonary fibrosis. Part II. Results of treatment. Discussion].
    Pneumonologia polska, 1980, Volume: 48, Issue:9

    Topics: Adult; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Pu

1980
The efficacy of preventive treatment with isoniazid in a high risk group. Results form an international Trial under the auspices of IUAT.
    Scandinavian journal of respiratory diseases. Supplementum, 1978, Volume: 102

    Topics: Clinical Trials as Topic; Drug Evaluation; Humans; Isoniazid; Placebos; Pulmonary Fibrosis; Time Fac

1978
[The role of preventive chemotherapy in the present tuberculosis epidemiology of GDR (author's transl)].
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1977, Volume: 147, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Female; Germany, East; Humans; Infant; Infant, Newborn;

1977

Other Studies

26 other studies available for isoniazid and Pulmonary Fibrosis

ArticleYear
Antifibrotics Effect of Liposome-Encapsulated Composition of Oxidized Dextran and Isonicotinic Acid Hydrazide in Mice with BCG-Induced Granulomatosis Depends on Administration Route.
    Bulletin of experimental biology and medicine, 2020, Volume: 169, Issue:1

    Topics: Animals; Antitubercular Agents; BCG Vaccine; Dextrans; Drug Compounding; Granuloma, Respiratory Trac

2020
Isoniazid and pulmonary fibrosis.
    Chinese medical journal, 2015, Mar-05, Volume: 128, Issue:5

    Topics: Adult; Antitubercular Agents; Humans; Isoniazid; Male; Pulmonary Fibrosis

2015
Pleural tuberculosis in a patient with untreated type 1 Gaucher disease.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2016, Volume: 22, Issue:1

    Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Ethambutol; Gaucher Disease; Humans; Isonia

2016
Phosphodiesterase-4 inhibition combined with isoniazid treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology.
    The American journal of pathology, 2011, Volume: 179, Issue:1

    Topics: Animals; Antitubercular Agents; Blotting, Western; Colony-Forming Units Assay; Cyclic Nucleotide Pho

2011
Experimental infective pneumoconiosis. IV. Massive pulmonary fibrosis produced by coal-mine dust and isoniazid-resistant tubercle bacilli of low virulence.
    British journal of experimental pathology, 1955, Volume: 36, Issue:6

    Topics: Bacillus; Coal; Dust; Isoniazid; Mining; Pneumoconiosis; Pulmonary Fibrosis; Tuberculosis; Tuberculo

1955
CLINICAL ASPECTS, MEDICAL AND SURGICAL, IN THE MANAGEMENT OF BATTEY-TYPE PULMONARY DISEASE.
    Diseases of the chest, 1964, Volume: 45

    Topics: Bronchiectasis; Calcification, Physiologic; Drug Resistance; Drug Resistance, Microbial; Epidemiolog

1964
[Introduction and general data on the subject of the pathology of drugs].
    Minerva medica, 1984, Aug-25, Volume: 75, Issue:32-33

    Topics: Agranulocytosis; Anemia, Hemolytic; Anemia, Megaloblastic; Anemia, Sideroblastic; Bleomycin; Bone Ma

1984
[Fibrosis formation in the lungs in tuberculosis during chemotherapy].
    Problemy tuberkuleza, 1980, Issue:5

    Topics: Adult; Antitubercular Agents; Female; Humans; Isoniazid; Male; Pulmonary Fibrosis; Radiography; Time

1980
[A health system that does not live up to expectations. A primary health care team attempt at an integrated approach to a case].
    Atencion primaria, 1996, Feb-29, Volume: 17, Issue:3

    Topics: Alcoholism; Angina Pectoris; Antitubercular Agents; Diagnosis, Differential; Humans; Isoniazid; Live

1996
[Antitubercular chemoprophylaxis after 20 years of its world-wide application].
    Minerva medica, 1979, Jan-14, Volume: 70, Issue:2

    Topics: Animals; BCG Vaccine; Cattle; Cortisone; Drug Therapy; Guinea Pigs; History, 20th Century; Hospitals

1979
Changes in the pulmonary uptake and binding of drugs in an experimental model of lung fibrosis.
    Toxicology and applied pharmacology, 1979, Volume: 49, Issue:3

    Topics: Animals; Dexamethasone; Disease Models, Animal; Isoniazid; Lung; Male; Paraquat; Penicillin G; Pulmo

1979
Pulmonary infiltrates and fever induced by isoniazid.
    Postgraduate medical journal, 1990, Volume: 66, Issue:778

    Topics: Aged; Aged, 80 and over; Bacterial Infections; Diagnosis, Differential; Drug Hypersensitivity; Femal

1990
[The pro-fibrotic and pro-oxidant action of isoniazid].
    Problemy tuberkuleza, 1990, Issue:8

    Topics: Animals; Isoniazid; Lipid Peroxidation; Pulmonary Fibrosis; Rats; Tuberculosis, Pulmonary

1990
Isoniazid-induced interstitial pneumonia.
    Respiratory medicine, 1989, Volume: 83, Issue:6

    Topics: Aged; Humans; Isoniazid; Male; Pulmonary Fibrosis

1989
[A case of interstitial pneumonia induced by isoniazid (INH)].
    Nihon Kyobu Shikkan Gakkai zasshi, 1987, Volume: 25, Issue:9

    Topics: Aged; Humans; Isoniazid; Lymphocyte Activation; Male; Pulmonary Fibrosis; Tuberculosis, Pulmonary

1987
[Results of examinations at admission time to the study of fibrous lesions and pulmonary tuberculosis].
    Bulletin of the International Union against Tuberculosis, 1974, Volume: 49, Issue:1

    Topics: Adult; Antitubercular Agents; Drug Resistance, Microbial; Humans; Isoniazid; Middle Aged; Mycobacter

1974
Chemotherapy of pulmonary tuberculosis with pneumoconiosis. Second report to the Medical Research Council from the Joint Investigators.
    Tubercle, 1967, Volume: 48, Issue:1

    Topics: Adult; Aged; Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Dr

1967
[Problems in the classification of certain types of segmentary allergic angitis].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1972, Sep-10, Volume: 48, Issue:37

    Topics: Diagnosis, Differential; Drug Hypersensitivity; Endarteritis; Humans; Hypersensitivity; Isoniazid; K

1972
[Characteristics of fibrous lesions].
    Bulletin of the International Union against Tuberculosis, 1974, Volume: 49, Issue:1

    Topics: Adult; Female; Health Surveys; Humans; Isoniazid; Male; Middle Aged; Placebos; Pulmonary Fibrosis; T

1974
Progressive lung disease in patients with tuberculosis and ankylosing spondylitis.
    Tubercle, 1974, Volume: 55, Issue:2

    Topics: Aged; Aminosalicylic Acids; Aspergillosis; Humans; Isoniazid; Male; Middle Aged; Pulmonary Fibrosis;

1974
Pulmonary fibrosis and group IV mycobacteria infection of the lungs in ankylosing spondylitis.
    The American review of respiratory disease, 1974, Volume: 109, Issue:2

    Topics: Adult; Autopsy; Ethambutol; Humans; Isoniazid; Lung Diseases; Male; Middle Aged; Mycobacterium; Myco

1974
The problem of preventive treatment with isoniazid in persons with fibrotic lesions in the lungs.
    Scandinavian journal of respiratory diseases, 1968, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Czechoslovakia; Female; Humans; Infan

1968
Polymyositis and interstitial lung disease.
    The American review of respiratory disease, 1972, Volume: 105, Issue:4

    Topics: Adult; Dermatomyositis; Female; Humans; Isoniazid; Middle Aged; Prednisone; Pulmonary Alveoli; Pulmo

1972
Tuberculosis risk in persons with "fibrotic" x-ray lesions.
    Bulletin of the International Union against Tuberculosis, 1972, Volume: 47

    Topics: Adolescent; Adult; Age Factors; Aged; Czechoslovakia; Female; Germany, East; Health Surveys; Humans;

1972
Tuberculosis among patients with various radiologic abnormalities, followed by the chest clinic service.
    The American review of respiratory disease, 1971, Volume: 104, Issue:4

    Topics: British Columbia; Humans; Isoniazid; Lung Diseases; Mass Chest X-Ray; Pleurisy; Pneumoconiosis; Pulm

1971
Serum lactic dehydrogenase activity and diffuse interstitial pneumonitis.
    JAMA, 1968, Jun-24, Volume: 204, Issue:13

    Topics: Adult; Aged; Aspartate Aminotransferases; Diagnosis, Differential; Female; Humans; Isoniazid; L-Lact

1968