isoniazid has been researched along with Porphyrias in 17 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of our previous studies demonstrated that isonicotinic acid hydrazide (INH) can aggravate griseofulvin (GF)-induced protoporphyria in mice." | 3.69 | Relationship between N-acetyltransferase (NAT) activity and liver protoporphyrin level in experimental porphyria. ( Irifune, H; Nonaka, S; Ohgami, T; Watanabe, M, 1996) |
| "In patients with peripheral neuropathies it was often possible to obtain nerve velocities with signal amplitudes as low as 0·1 μV and these were often slower than those obtained from the normal subjects." | 1.25 | Sensory conduction in peroneal and posterior tibial nerves using averaging techniques. ( Lovelace, RE; Myers, SJ; Zablow, L, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (88.24) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| RUMLER, W | 1 |
| SANTAGOSTINI, F | 1 |
| Watanabe, M | 2 |
| Irifune, H | 1 |
| Ohgami, T | 1 |
| Nonaka, S | 1 |
| Daun, H | 1 |
| Diukov, VA | 1 |
| Kotal, P | 2 |
| Klepácek, I | 2 |
| Jirsa, M | 2 |
| Kordac, V | 2 |
| Martasek, P | 1 |
| Cavanagh, JB | 1 |
| Lovelace, RE | 1 |
| Myers, SJ | 1 |
| Zablow, L | 1 |
| Solís Herruzo, JA | 1 |
| Pérez Peña, F | 1 |
| Lamy, M | 1 |
| Gryglewski, R | 1 |
| Pruzanski, W | 1 |
| Adler, H | 1 |
| Kalow, W | 1 |
| Kalmus, H | 1 |
| Kosower, NS | 1 |
| Rock, RA | 1 |
4 reviews available for isoniazid and Porphyrias
| Article | Year |
|---|---|
[Pharmacogenetic research in clinical psychiatry].
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Chlorpromazine; Cholinesteras | 1976 |
Peripheral neuropathy caused by chemical agents.
Topics: Acrylamides; Animals; Arsenic; Axons; Carbon Disulfide; Disulfiram; Humans; In Vitro Techniques; Iso | 1973 |
[Erythropoietic protoporphyria (II. Pathogenesis, physiopathology and treatment)].
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Antimalarials; Diet Therapy; Erythropoiesis; Glucoc | 1973 |
[Medical pharmacogenetics. I. Methods applied in pharmacogenetic studies].
Topics: Catecholamines; Genetics, Medical; Humans; Isoniazid; Methemoglobinemia; Methods; Pharmacogenetics; | 1967 |
13 other studies available for isoniazid and Porphyrias
| Article | Year |
|---|---|
[ON PHARMACOGENETICS].
Topics: Abnormalities, Drug-Induced; Catalase; Enzyme Inhibitors; Glucosephosphate Dehydrogenase Deficiency; | 1963 |
[PHARMACOGENETICS].
Topics: Anemia; Anemia, Hemolytic; Barbiturates; Catalase; Cholinesterases; Genetics, Medical; Glucosephosph | 1964 |
Relationship between N-acetyltransferase (NAT) activity and liver protoporphyrin level in experimental porphyria.
Topics: Animals; Arylamine N-Acetyltransferase; Drug Synergism; Griseofulvin; Isoniazid; Liver; Male; Mice; | 1996 |
[Polyneuropathies as a diagnostic and therapeutic task].
Topics: Adult; Alcoholic Intoxication; Botulism; Child; Diabetic Neuropathies; Diagnosis, Differential; Diph | 1977 |
The synergistic effect of isonicotinic acid hydrazide (INH) and griseofulvin (GF) on porphyrin metabolism.
Topics: Animals; Drug Synergism; Drug Therapy, Combination; Griseofulvin; Isoniazid; Liver; Mice; Porphyrias | 1991 |
[Inhibition of porphyrin synthesis by isonicotinic acid hydrazide in models simulating porphyria].
Topics: Animals; Chick Embryo; Isoniazid; Liver; Porphyrias; Porphyrins; Pyridoxal Phosphate; Saccharomyces | 1989 |
Porphyrinostatic effect of isonicotinic acid hydrazide on porphyric chick embryo and yeast.
Topics: 5-Aminolevulinate Synthetase; Animals; Chick Embryo; Isoniazid; Liver; Liver Diseases; Porphyrias; P | 1988 |
Sensory conduction in peroneal and posterior tibial nerves using averaging techniques.
Topics: Action Potentials; Adolescent; Adult; Aged; Computers, Analog; Diabetic Neuropathies; Electric Stimu | 1973 |
[Pharmacogenetics].
Topics: Barbiturates; Female; Glucosephosphate Dehydrogenase Deficiency; Heterozygote; Humans; Isoniazid; Ma | 1972 |
Myotonic dystrophy, acute intermittent porphyria and neurofibromatosis in one patient.
Topics: Aminosalicylic Acids; Cataract; Cervical Vertebrae; Humans; Isoniazid; Male; Middle Aged; Myotonic D | 1966 |
Genetic factors in adverse drug reactions.
Topics: Anesthesia, General; Barbiturates; Cholinesterases; Drug-Related Side Effects and Adverse Reactions; | 1971 |
Scope and limitations of pharmacogenetics.
Topics: Animals; Barbiturates; Cholinesterases; Dextrans; Favism; Genes; Genetics; Genetics, Medical; Glucos | 1968 |
Seizures in experimental porphyria.
Topics: Amides; Animals; Female; Isoniazid; Porphyrias; Porphyrins; Pyridoxal Phosphate; Pyridoxine; Rats; S | 1968 |