isoniazid has been researched along with Polyneuropathies in 30 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Polyneuropathies: Diseases of multiple peripheral nerves simultaneously. Polyneuropathies usually are characterized by symmetrical, bilateral distal motor and sensory impairment with a graded increase in severity distally. The pathological processes affecting peripheral nerves include degeneration of the axon, myelin or both. The various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology, or by pattern of inheritance.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Development of polyneuropathy (PNP) under treatment for tuberculosis (TB), including isoniazid (INH), is a highly relevant adverse drug effect." | 7.81 | Isoniazid-induced polyneuropathy in a tuberculosis patient - implication for individual risk stratification with genotyping? ( Hartmann, CJ; Hartung, HP; Kieseier, BC; Konta, L; Pabst, T; Steinberger, D; Stettner, M, 2015) |
| " It is evident that guidelines established for the prevention and treatment of this problem differ between industrialised and developing countries, and that further research is needed to define the optimum dosing of pyridoxine supplementation in populations where there is a significant burden of TB and HIV." | 6.47 | Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review. ( Benatar, M; Harrison, TB; Heckmann, JM; van der Watt, JJ, 2011) |
| "Development of polyneuropathy (PNP) under treatment for tuberculosis (TB), including isoniazid (INH), is a highly relevant adverse drug effect." | 3.81 | Isoniazid-induced polyneuropathy in a tuberculosis patient - implication for individual risk stratification with genotyping? ( Hartmann, CJ; Hartung, HP; Kieseier, BC; Konta, L; Pabst, T; Steinberger, D; Stettner, M, 2015) |
| " It is evident that guidelines established for the prevention and treatment of this problem differ between industrialised and developing countries, and that further research is needed to define the optimum dosing of pyridoxine supplementation in populations where there is a significant burden of TB and HIV." | 2.47 | Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review. ( Benatar, M; Harrison, TB; Heckmann, JM; van der Watt, JJ, 2011) |
| " The dosage used according to this protocol varied greatly, going from 1." | 1.27 | [Value of determining plasma INH during antitubercular treatment. Retrospective analysis of 204 cases]. ( Cheminat, JC; Ducarrouge, C; Lavarenne, J; Molina, C; Paire, M, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (90.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stettner, M | 1 |
| Steinberger, D | 1 |
| Hartmann, CJ | 1 |
| Pabst, T | 1 |
| Konta, L | 1 |
| Hartung, HP | 1 |
| Kieseier, BC | 1 |
| van der Watt, JJ | 2 |
| Benatar, MG | 1 |
| Harrison, TB | 2 |
| Carrara, H | 1 |
| Heckmann, JM | 2 |
| Benatar, M | 1 |
| Cheminat, JC | 1 |
| Paire, M | 1 |
| Lavarenne, J | 1 |
| Ducarrouge, C | 1 |
| Molina, C | 1 |
| Sahn, SA | 1 |
| Lakshminarayan, S | 1 |
| Daun, H | 2 |
| Mumenthaler, M | 1 |
| Smirnov, GA | 1 |
| Poklonskaia, AIa | 1 |
| Ndiaye, IP | 1 |
| Ndiaye, MM | 1 |
| Mauferon, JB | 1 |
| Diagne, M | 1 |
| Diop, AG | 1 |
| Bammer, HG | 1 |
| Klinghardt, GW | 1 |
| Reniers, J | 1 |
| Martin, L | 1 |
| Hildebrand, J | 1 |
| Kenis, Y | 1 |
| Thibault, H | 1 |
| Lamy, M | 1 |
| Gottwald, W | 1 |
| Favez, G | 1 |
| Wiser, H | 1 |
| Evans, DA | 1 |
| Schalterand, G | 1 |
| Waser, PG | 1 |
| Selaimen, F | 1 |
| da Motta, PE | 1 |
| Cunha, DF | 1 |
| Gibbels, E | 1 |
| Wasik, A | 1 |
| Scheid, W | 1 |
| Renard, J | 1 |
| Bertrand, Y | 1 |
| Puvinel, B | 1 |
| Mezard, F | 1 |
| Suchenwirth, R | 1 |
| Faĭnberg, MG | 1 |
| Goedde, HW | 1 |
| Schloot, W | 1 |
| Kunovskiĭ, BV | 1 |
| Kats, NIa | 1 |
3 reviews available for isoniazid and Polyneuropathies
| Article | Year |
|---|---|
Polyneuropathy, anti-tuberculosis treatment and the role of pyridoxine in the HIV/AIDS era: a systematic review.
Topics: Antitubercular Agents; HIV Infections; Humans; Isoniazid; Polyneuropathies; Practice Guidelines as T | 2011 |
[Neurological aspects of the vitamin B complex].
Topics: Alcoholism; Anticonvulsants; Cyanides; Deficiency Diseases; Electroencephalography; Erythrocytes; Fo | 1972 |
Genetic factors in drug therapy.
Topics: Adolescent; Aged; Alcohol Oxidoreductases; Animals; Anticoagulants; Child; Female; Glaucoma; Humans; | 1969 |
27 other studies available for isoniazid and Polyneuropathies
| Article | Year |
|---|---|
Isoniazid-induced polyneuropathy in a tuberculosis patient - implication for individual risk stratification with genotyping?
Topics: Adult; Arylamine N-Acetyltransferase; Genetic Association Studies; Humans; Isoniazid; Male; Polymorp | 2015 |
Isoniazid exposure and pyridoxine levels in human immunodeficiency virus associated distal sensory neuropathy.
Topics: Adult; Antiretroviral Therapy, Highly Active; Arylamine N-Acetyltransferase; Coinfection; Female; HI | 2015 |
[Value of determining plasma INH during antitubercular treatment. Retrospective analysis of 204 cases].
Topics: Acetylation; Adult; Chemical and Drug Induced Liver Injury; Depression; Female; Humans; Isoniazid; K | 1983 |
Tuberculosis after corticosteroid therapy.
Topics: Adrenal Cortex Hormones; Adult; Aged; Airway Obstruction; Arthritis, Rheumatoid; Dermatitis, Exfolia | 1976 |
[Polyneuropathies as a diagnostic and therapeutic task].
Topics: Adult; Alcoholic Intoxication; Botulism; Child; Diabetic Neuropathies; Diagnosis, Differential; Diph | 1977 |
[Exotoxin-induced polyneuropathies].
Topics: Acrylamides; Carbon Tetrachloride Poisoning; DDT; Disulfiram; Ethanol; Humans; Hydralazine; Isoniazi | 1975 |
[Cocarboxylase treatment of adverse disorders caused by isoniazid].
Topics: Adult; Aged; Female; Humans; Isoniazid; Male; Middle Aged; Polyneuropathies; Thiamine Pyrophosphate | 1976 |
[Etiological aspects of polyneuritis in Senegal].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcoholism; Charcot-Marie-Tooth Disease; Child; Diabetic | 1989 |
[Relations between polyneuropathies produced by certain modern drugs, by malabsorption and by malnutrition].
Topics: Animals; Isoniazid; Malabsorption Syndromes; Nitrofurans; Peripheral Nervous System Diseases; Polyne | 1969 |
Denervation atrophy in isoniazid polyneuropathy. Histo-enzymatic study.
Topics: Adenosine Triphosphatases; Chronaxy; Electromyography; Extremities; Glucosyltransferases; Histocytoc | 1967 |
Additive toxicity of vincristine and other drugs for the peripheral nervous system. Three case reports.
Topics: Adult; Asparaginase; Female; Humans; Isoniazid; Male; Middle Aged; Neoplasms; Peripheral Nerves; Per | 1971 |
[Uncommon reactions to isoniazid].
Topics: Central Nervous System; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Drug Interact | 1973 |
[Polyneuritides caused by drugs].
Topics: Humans; Isoniazid; Nitrofurantoin; Polyneuropathies; Vincristine | 1972 |
[Pharmacogenetics].
Topics: Barbiturates; Female; Glucosephosphate Dehydrogenase Deficiency; Heterozygote; Humans; Isoniazid; Ma | 1972 |
[Neurologic-psychiatric complications of tuberculosis chemotherapy with special reference to simultaneous anticonvulsive therapy].
Topics: Antitubercular Agents; Humans; Hydantoins; Isoniazid; Polyneuropathies; Psychoses, Substance-Induced | 1973 |
[Side effects of tuberculostatics (author's transl)].
Topics: Adult; Antitubercular Agents; Drug Hypersensitivity; Ear; Ethambutol; Female; Humans; Isoniazid; Liv | 1973 |
[Management and prognosis of INH-induced neuritis?].
Topics: Brachial Plexus; Humans; Isoniazid; Paralysis; Polyneuropathies; Prognosis; Time Factors; Vitamin B | 1971 |
[Pharmacogenetics].
Topics: Anemia, Hemolytic; Antipyrine; DNA; Drug-Related Side Effects and Adverse Reactions; Europe; Glucose | 1967 |
[Use of B6, B1, B12 vitamins in polyneuritis due to the use of isonicotinic acid hydrazine].
Topics: Adult; Female; Humans; Hydrazines; Injections, Intramuscular; Isoniazid; Isonicotinic Acids; Male; M | 1970 |
[Differential diagnosis of polyneuritides].
Topics: Arsenic Poisoning; Carbon Disulfide; Diabetic Neuropathies; Diagnosis, Differential; Diphtheria; Hum | 1969 |
Mental disorders caused by isonicotinic acid hydrazide (INH) in the course of treatment of pulmonary tuberculosis.
Topics: Affective Symptoms; Age Factors; Alcoholism; Central Nervous System Diseases; Delirium; Delusions; E | 1970 |
[Toxic polyneuritis].
Topics: Arsenic; Drug-Related Side Effects and Adverse Reactions; Ethanol; Germany, West; Humans; Isoniazid; | 1970 |
[On the usefulness of vitamin B 6 during treatment with isoniazid].
Topics: Animals; Humans; Isoniazid; Mental Disorders; Polyneuropathies; Transaminases; Tuberculosis, Pulmona | 1967 |
[Polyneuritis (polyneuropathy) of drug origin].
Topics: Anticonvulsants; Humans; Isoniazid; Nitrofurantoin; Polyneuropathies; Thalidomide | 1968 |
[Clinical course and treatment of tubazide-induced polyneuritis].
Topics: Adult; Humans; Isoniazid; Middle Aged; Polyneuropathies | 1968 |
[Investigations into the polymorphism of acetylation of isonicotinic acid hydrazid (INH)].
Topics: Asian People; Female; Genetics, Population; Humans; Isoniazid; Polymorphism, Genetic; Polyneuropathi | 1968 |
[Pronounced Tubazid-induced polyneuritis in a patient with pulmonary tuberculosis].
Topics: Adult; Humans; Isoniazid; Male; Polyneuropathies; Tuberculosis, Pulmonary | 1966 |