isoniazid has been researched along with Peripheral Nerve Diseases in 79 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is well known that in the treatment of tuberculosis with isoniazid the complication of peripheral neuritis may arise." | 7.64 | Peripheral neuritis due to isoniazid. ( ANDREWS, RH; DEVADATTA, S; FOX, W; GANGADHARAM, PR; RAMAKRISHNAN, CV; SELKON, JB; VELU, S, 1960) |
| " Prophylactic pyridoxine supplementation during short-course chemotherapy for tuberculosis is not generally necessary in the daily 'A' regimen, but should be maintained in the twice-weekly (high-dose isoniazid) 'B' regimen for adults and children over 20 kg." | 4.77 | Acetylator phenotype and short-course chemotherapy for tuberculosis in Papua New Guinea. ( Currie, B; Hudson, B; Krause, V; Mondia, P, 1989) |
| "A 56-year old patient presented 3 months after initiation of an antituberculous regimen with Isoniacid (INH, 5 mg/kg daily), Ethambutol (20 mg/kg daily) and Rifampicin (675 mg daily) a mild sensory polyneuropathy and a bilateral retrobulbar neuritis which progressed to a severe optic atrophy." | 3.67 | Neurotoxicity of antituberculous drugs in a patient without active tuberculosis. ( Leppert, D; Waespe, W, 1988) |
| "Large single doses if isoniazid by mouth (1--2g/kg) have been shown to produce in rats Wallerian degeneration visible with the light microscope from the third day onwards." | 3.66 | Studies on the early changes in acute isoniazid neuropathy in the rat. ( Cavanagh, JB; Jacobs, JM; Miller, RH; Whittle, A, 1979) |
| "It is well known that in the treatment of tuberculosis with isoniazid the complication of peripheral neuritis may arise." | 3.64 | Peripheral neuritis due to isoniazid. ( ANDREWS, RH; DEVADATTA, S; FOX, W; GANGADHARAM, PR; RAMAKRISHNAN, CV; SELKON, JB; VELU, S, 1960) |
| "Isoniazid is an essential drug in the management of tuberculosis but there is a high degree of variation in the Indian population's capacity to acetylate or inactivate isoniazid to the inactive metabolite acetyl isoniazid, and they can be distinctly characterized phenotypically as being either slow or rapid inactivators (the concentration of the enzyme being higher in rapid inactivators)." | 1.56 | A case series of three patients presenting with isoniazid induced toxicity and N-acetyl transferase 2 gene mutation: A management conundrum for programmatic therapy of tuberculosis in India. ( Darole, P; Munshi, R; Panchal, F; Shetty, P; Sundar, U, 2020) |
| " However, their neurotoxicity could cause adverse effect and the patients with end-stage renal disease are especially vulnerable due to the reduction in renal drug clearance." | 1.48 | Ethambutol and isoniazid induced severe neurotoxicity in a patient undergoing continuous ambulatory peritoneal dialysis. ( Chen, Y; Li, H; Peng, H; Si, M, 2018) |
| " Pyridoxine is preventative in low dosage and curative in high dosage." | 1.33 | [Isoniazid induced neuropathy: consider prevention]. ( De Broucker, T; Martinez-Almoyna, L; Steichen, O, 2006) |
| "Pyridoxine may cause peripheral neuropathy and this case illustrates the need for caution in the use of this vitamin in the prevention and treatment of isoniazid induced peripheral neuropathy." | 1.28 | Exacerbation of isoniazid induced peripheral neuropathy by pyridoxine. ( Agnew, RA; Bucknall, RC; Nisar, M; Watkin, SW, 1990) |
| "Chronic dosing of rats with isoniazid (INH) leads to an increase in the incidence of short "spontaneous" sprouts on motor end plates in the rat sternocostalis muscle." | 1.27 | The effects of chronic isoniazid intoxication on motor end plate sprouting in rat sternocostalis muscle and on responses to partial denervation and local botulinum toxin. ( Cavanagh, JB; Kemplay, S, 1984) |
| " The conduction velocity tended to decrease in the high ethambutol dosage (200 gm or more) group compared with the low dosage (200 gm or less) group." | 1.26 | Peripheral nerve conduction function in patients treated with antituberculotic agents, with special reference to ethambutol and isoniazid. ( Sanagi, S; Takahashi, M; Takenaka, H; Takeuchi, H; Tarui, S, 1980) |
| "In patients with peripheral neuropathies it was often possible to obtain nerve velocities with signal amplitudes as low as 0·1 μV and these were often slower than those obtained from the normal subjects." | 1.25 | Sensory conduction in peroneal and posterior tibial nerves using averaging techniques. ( Lovelace, RE; Myers, SJ; Zablow, L, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 57 (72.15) | 18.7374 |
| 1990's | 7 (8.86) | 18.2507 |
| 2000's | 4 (5.06) | 29.6817 |
| 2010's | 9 (11.39) | 24.3611 |
| 2020's | 2 (2.53) | 2.80 |
| Authors | Studies |
|---|---|
| Shetty, P | 1 |
| Panchal, F | 1 |
| Munshi, R | 1 |
| Sundar, U | 1 |
| Darole, P | 1 |
| Choudhary, CR | 1 |
| Kumari, J | 1 |
| Advani, M | 1 |
| Si, M | 1 |
| Li, H | 1 |
| Chen, Y | 1 |
| Peng, H | 1 |
| Jortner, BS | 1 |
| Conradie, F | 1 |
| Mabiletsa, T | 1 |
| Sefoka, M | 1 |
| Mabaso, S | 1 |
| Louw, R | 1 |
| Evans, D | 2 |
| Van Rie, A | 1 |
| Kiwuwa-Muyingo, S | 1 |
| Kikaire, B | 1 |
| Mambule, I | 1 |
| Musana, H | 2 |
| Musoro, G | 2 |
| Gilks, CF | 1 |
| Levin, JB | 1 |
| Walker, AS | 2 |
| Arenas-Pinto, A | 1 |
| Thompson, J | 1 |
| Lugemwa, A | 1 |
| Kambugu, A | 2 |
| Mweemba, A | 1 |
| Atwongyeire, D | 1 |
| Thomason, MJ | 1 |
| Paton, NI | 1 |
| Arsalan, R | 1 |
| Sabzwari, S | 1 |
| Sekaggya-Wiltshire, C | 1 |
| von Braun, A | 1 |
| Scherrer, AU | 1 |
| Manabe, YC | 1 |
| Buzibye, A | 1 |
| Muller, D | 1 |
| Ledergerber, B | 1 |
| Gutteck, U | 1 |
| Corti, N | 1 |
| Byakika-Kibwika, P | 1 |
| Lamorde, M | 1 |
| Castelnuovo, B | 1 |
| Fehr, J | 1 |
| Kamya, MR | 1 |
| Takuva, S | 1 |
| Rassool, M | 1 |
| Firnhaber, C | 1 |
| Maskew, M | 1 |
| Zaoui, A | 1 |
| Abdelghani, A | 1 |
| Ben Salem, H | 1 |
| Ouanes, W | 1 |
| Hayouni, A | 1 |
| Khachnaoui, F | 1 |
| Rejeb, N | 1 |
| Benzarti, M | 1 |
| JONES, WA | 1 |
| JONES, GP | 1 |
| LUBING, HN | 1 |
| GAUTHIER, M | 1 |
| Carlson, HB | 1 |
| Anthony, EM | 1 |
| Russell, WF | 1 |
| Middlebrook, G | 1 |
| DEVADATTA, S | 2 |
| GANGADHARAM, PR | 2 |
| ANDREWS, RH | 1 |
| FOX, W | 1 |
| RAMAKRISHNAN, CV | 1 |
| SELKON, JB | 1 |
| VELU, S | 1 |
| BAHRS, G | 1 |
| SPILLANE, JD | 1 |
| WHEATE, HW | 1 |
| ASPINALL, DL | 1 |
| SCHALAEPFER, WW | 1 |
| HAGER, H | 3 |
| SCHLAEPFER, WW | 2 |
| MARTIN, U | 1 |
| MANDEL, W | 1 |
| Steichen, O | 1 |
| Martinez-Almoyna, L | 1 |
| De Broucker, T | 1 |
| Hori, S | 1 |
| Bahemuka, M | 2 |
| Kioy, PM | 1 |
| Wanjama, M | 1 |
| Wainaina, CM | 1 |
| Takeuchi, H | 1 |
| Takahashi, M | 1 |
| Tarui, S | 1 |
| Sanagi, S | 1 |
| Takenaka, H | 1 |
| Colip, MP | 1 |
| Baughman, S | 1 |
| Peterson, RG | 1 |
| Kanareĭkin, KF | 1 |
| Babenkova, SV | 1 |
| Manvelov, LS | 1 |
| Eskin, MA | 1 |
| Snider, DE | 1 |
| Caselli, MA | 1 |
| Prywes, HC | 1 |
| Sharnoff, DG | 1 |
| Chua, CL | 1 |
| Ohnishi, A | 1 |
| Tateishi, J | 1 |
| Kuroiwa, Y | 1 |
| Pickwell, SM | 1 |
| Kemplay, S | 1 |
| Cavanagh, JB | 4 |
| Gohel, D | 1 |
| Oza, JJ | 1 |
| Panicker, MG | 1 |
| Yamamoto, M | 1 |
| Sobue, G | 1 |
| Mukoyama, M | 1 |
| Matsuoka, Y | 1 |
| Mitsuma, T | 1 |
| Breen, RA | 1 |
| Lipman, MC | 1 |
| Johnson, MA | 1 |
| Naba, I | 1 |
| Yoshikawa, H | 1 |
| Sakoda, S | 1 |
| Itabe, H | 1 |
| Suzuki, H | 1 |
| Kodama, T | 1 |
| Yanagihara, T | 1 |
| Hernán, MA | 1 |
| Robins, JM | 1 |
| Daun, H | 1 |
| Jacobs, JM | 2 |
| Miller, RH | 2 |
| Whittle, A | 1 |
| Duroux, P | 1 |
| Goel, UC | 1 |
| Bajaj, S | 1 |
| Gupta, OP | 1 |
| Dwivedi, NC | 1 |
| Dubey, AL | 1 |
| Mahashur, AA | 1 |
| Figg, WD | 1 |
| Nisar, M | 1 |
| Watkin, SW | 1 |
| Bucknall, RC | 1 |
| Agnew, RA | 1 |
| Currie, B | 1 |
| Krause, V | 1 |
| Mondia, P | 1 |
| Hudson, B | 1 |
| Leppert, D | 1 |
| Waespe, W | 1 |
| Beuche, W | 1 |
| Friede, RL | 1 |
| Thomas, PK | 2 |
| Smith, B | 1 |
| Schröder, JM | 3 |
| Klinghardt, GW | 1 |
| Gibson, FD | 1 |
| Phillips, S | 1 |
| Levy, L | 1 |
| Higgins, LJ | 1 |
| Burbridge, TN | 1 |
| Olsson, Y | 2 |
| Fullerton, PM | 1 |
| Ochoa, J | 1 |
| Johansson, B | 1 |
| Bischoff, A | 1 |
| Hildebrand, J | 1 |
| Kenis, Y | 1 |
| Hopkins, AP | 1 |
| Lambert, EH | 1 |
| Goldman, AL | 1 |
| Braman, SS | 1 |
| Aita, JF | 1 |
| Calame, TR | 1 |
| Lovelace, RE | 1 |
| Myers, SJ | 1 |
| Zablow, L | 1 |
| Tomkin, GH | 1 |
| Schulze, B | 1 |
| Takayanagi, T | 1 |
| Sobue, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Trial to Describe the Pharmacokinetics, Safety and Efficacy of Pharmacogenetics-guided Dosing of Isoniazid in Patients With HIV-associated TB[NCT05124678] | Phase 2 | 40 participants (Anticipated) | Interventional | 2021-12-07 | Recruiting | ||
| A Randomized, Four-arm Open Label Phase Two-b Clinical Trial to Evaluate the Pharmacokinetics, Safety/Tolerability and Efficacy of High Dose Rifampicin in TB-HIV Co-infected Patients on Efavirenz- or Dolutegravir-based Antiretroviral Therapy[NCT03982277] | Phase 2 | 130 participants (Actual) | Interventional | 2019-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for isoniazid and Peripheral Nerve Diseases
| Article | Year |
|---|---|
[Adverse effects and safety of antimicrobial agents-neurotoxicities].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; beta-Lactams; Central Nervous System Diseases; Drug | 2007 |
[Exogenous toxic polyneuropathies].
Topics: Adult; Anti-Bacterial Agents; Antineoplastic Agents; Carbon Disulfide; Carbon Monoxide Poisoning; Fe | 1981 |
Pyridoxine supplementation during isoniazid therapy.
Topics: Humans; Isoniazid; Peripheral Nervous System Diseases; Pyridoxine; Tuberculosis; Vitamin B 6 Deficie | 1980 |
Acetylator phenotype and short-course chemotherapy for tuberculosis in Papua New Guinea.
Topics: Acetylation; Drug Administration Schedule; Humans; Isoniazid; Papua New Guinea; Peripheral Nervous S | 1989 |
The morphological basis for alterations in nerve conduction in peripheral neuropathy.
Topics: Amyloidosis; Animals; Axons; Beriberi; Cresols; Demyelinating Diseases; Diabetic Neuropathies; Diffu | 1971 |
Peripheral neuropathy.
Topics: Arsenic Poisoning; Deficiency Diseases; Humans; Isoniazid; Lead Poisoning; Metabolic Diseases; Neopl | 1970 |
[Side effects of drugs. 4. Drug induced polyneuropathies and myopathies].
Topics: Adrenocorticotropic Hormone; Chloroquine; Glucocorticoids; Humans; Hydralazine; Isoniazid; Muscular | 1969 |
Peripheral neuropathy caused by chemical agents.
Topics: Acrylamides; Animals; Arsenic; Axons; Carbon Disulfide; Disulfiram; Humans; In Vitro Techniques; Iso | 1973 |
3 trials available for isoniazid and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Prevalence, incidence and predictors of peripheral neuropathy in African adults with HIV infection within the DART trial.
Topics: Adolescent; Adult; Aged; Anti-Retroviral Agents; Antitubercular Agents; Didanosine; Female; HIV Infe | 2014 |
Peripheral neuropathy in HIV patients in sub-Saharan Africa failing first-line therapy and the response to second-line ART in the EARNEST trial.
Topics: Adult; Africa South of the Sahara; Alcohol Abstinence; Anti-HIV Agents; Antiretroviral Therapy, High | 2016 |
Isoniazid-induced vitamin B6 deficiency. Metabolic studies and preliminary vitamin B6 excretion studies.
Topics: Aspartate Aminotransferases; Blood Urea Nitrogen; Erythrocytes; Humans; Isoniazid; Leukocyte Count; | 1967 |
68 other studies available for isoniazid and Peripheral Nerve Diseases
| Article | Year |
|---|---|
A case series of three patients presenting with isoniazid induced toxicity and N-acetyl transferase 2 gene mutation: A management conundrum for programmatic therapy of tuberculosis in India.
Topics: Adolescent; Adult; Antitubercular Agents; Arylamine N-Acetyltransferase; Chemical and Drug Induced L | 2020 |
Isoniazid induced early-onset of motor dominant neuropathy and treatment with high dose of pyridoxine.
Topics: Adult; Antitubercular Agents; Diagnosis, Differential; Female; Humans; Isoniazid; Peripheral Nervous | 2018 |
Ethambutol and isoniazid induced severe neurotoxicity in a patient undergoing continuous ambulatory peritoneal dialysis.
Topics: Adult; Antitubercular Agents; Ethambutol; Humans; Isoniazid; Kidney Failure, Chronic; Male; Optic Ne | 2018 |
Nerve Fiber Regeneration in Toxic Peripheral Neuropathy.
Topics: Animals; Axons; Carbon Disulfide; Isoniazid; Nerve Fibers; Nerve Regeneration; Organophosphates; Per | 2020 |
Prevalence and incidence of symmetrical symptomatic peripheral neuropathy in patients with multidrug-resistant TB.
Topics: Humans; Incidence; Isoniazid; Isoxazoles; Oxazolidinones; Peripheral Nervous System Diseases; Preval | 2013 |
Isoniazid induced motor-dominant neuropathy.
Topics: Antitubercular Agents; Female; Humans; Isoniazid; Middle Aged; Muscle Weakness; Peripheral Nervous S | 2015 |
Anti-TB drug concentrations and drug-associated toxicities among TB/HIV-coinfected patients.
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Coinfection; Female; HIV Infec | 2017 |
Anti-TB drug concentrations and drug-associated toxicities among TB/HIV-coinfected patients.
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Coinfection; Female; HIV Infec | 2017 |
Anti-TB drug concentrations and drug-associated toxicities among TB/HIV-coinfected patients.
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Coinfection; Female; HIV Infec | 2017 |
Anti-TB drug concentrations and drug-associated toxicities among TB/HIV-coinfected patients.
Topics: Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Coinfection; Female; HIV Infec | 2017 |
Prevalence of peripheral neuropathy in antiretroviral therapy naïve HIV-positive patients and the impact on treatment outcomes--a retrospective study from a large urban cohort in Johannesburg, South Africa.
Topics: Adult; Anti-HIV Agents; Antitubercular Agents; Coinfection; Female; HIV Infections; HIV-1; Humans; I | 2012 |
Early-onset severe isoniazid-induced motor-dominant neuropathy: a case report.
Topics: Adult; Antitubercular Agents; Humans; Isoniazid; Male; Motor Neuron Disease; Peripheral Nervous Syst | 2012 |
Peripheral neuropathy due to isoniazid; report of two cases.
Topics: Disease; Isoniazid; Niacin; Nicotinic Acids; Peripheral Nerves; Peripheral Nervous System Diseases; | 1953 |
Peripheral neuropathy in tuberculosis patients treated with isoniazid.
Topics: Isoniazid; Niacin; Nicotinic Acids; Peripheral Nerves; Peripheral Nervous System Diseases; Tuberculo | 1953 |
[Peripheral nerve disorders in pulmonary tuberculosis patients treated with isoniazid and its derivatives].
Topics: Disease; Isoniazid; Niacin; Nicotinic Acids; Peripheral Nerves; Peripheral Nervous System Diseases; | 1955 |
Prophylaxis of isoniazid neuropathy with pyridoxine.
Topics: Humans; Isomerism; Isoniazid; Nervous System Diseases; Niacin; Nicotinic Acids; Peripheral Nervous S | 1956 |
Peripheral neuritis due to isoniazid.
Topics: Africa, Eastern; Folic Acid; Humans; India; Isoniazid; Neuritis; Peripheral Nervous System Diseases; | 1960 |
[On the effect of INHG (gluronacid) on experimental INH rat neuropathy].
Topics: Animals; Isoniazid; Paralysis; Peripheral Nerves; Peripheral Nervous System Diseases; Rats | 1961 |
IATROGENIC NEUROLOGICAL DISEASES. DRUG-INDUCED NEUROLOGICAL DISORDERS.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antihypertensive Agents | 1964 |
TWO UNUSUAL CASES OF NERVE ABSCESS.
Topics: Abscess; Humans; Isoniazid; Leprosy; Nerve Tissue; Peripheral Nervous System Diseases; Prednisolone; | 1964 |
MULTIPLE DEFICIENCY STATE ASSOCIATED WITH ISONIAZID THERAPY.
Topics: Anxiety; Depression; Ethionamide; Feeding and Eating Disorders; Isoniazid; Mental Disorders; Niacin; | 1964 |
ULTRASTRUCTURAL STUDIES OF INH-INDUCED NEUROPATHY IN RATS. I. EARLY AXONAL CHANGES.
Topics: Axons; Electrons; Isoniazid; Microscopy; Microscopy, Electron; Microscopy, Phase-Contrast; Pathology | 1964 |
ULTRASTRUCTURAL STUDIES OF INH-INDUCED NEUROPATHY IN RATS. II. ALTERATION AND DECOMPOSITION OF THE MYELIN SHEATH.
Topics: Cytoplasm; Demyelinating Diseases; Electrons; Isoniazid; Macrophages; Microscopy; Microscopy, Electr | 1964 |
ULTRASTRUCTURAL STUDIES OF INH-INDUCED NEUROPATHY IN RATS. 3. REPAIR AND REGENERATION.
Topics: Axons; Electrons; Isoniazid; Microscopy; Microscopy, Electron; Microscopy, Phase-Contrast; Myelin Sh | 1964 |
ISONIAZID-INDUCED ENCEPHALOPATHY.
Topics: Brain Diseases; Drug Therapy; Epilepsy; Epilepsy, Tonic-Clonic; Isoniazid; Peripheral Nervous System | 1965 |
[Burning-feet-syndrome caused by overdose of isoniazid].
Topics: Drug Overdose; Foot Diseases; Isoniazid; Niacin; Nicotinic Acids; Peripheral Nervous System Diseases | 1955 |
Pyridoxine and the isoniazid-induced neuropathy.
Topics: Humans; Isoniazid; Peripheral Nervous System Diseases; Pyridoxine; Vitamin B 6 | 1959 |
[Isoniazid induced neuropathy: consider prevention].
Topics: Acetylation; Achilles Tendon; Adult; Antiretroviral Therapy, Highly Active; Antitubercular Agents; E | 2006 |
Electrophysiological evidence of peripheral nerve damage in patients treated with isoniazid.
Topics: Adolescent; Adult; Antitubercular Agents; Child; Drug Combinations; Electromyography; Female; Humans | 1982 |
Peripheral nerve conduction function in patients treated with antituberculotic agents, with special reference to ethambutol and isoniazid.
Topics: Action Potentials; Adolescent; Adult; Aged; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged | 1980 |
Alteration of fucose/leucine incorporation into PNS myelin by isoniazid neuropathy.
Topics: Animals; Fucose; Isoniazid; Leucine; Male; Myelin Proteins; Peripheral Nervous System Diseases; Rats | 1981 |
Neurotoxicity in relation to tropical peripheral neuropathy: a re-appraisal.
Topics: Antidiarrheals; Cyanides; Hereditary Sensory and Autonomic Neuropathies; Humans; Isoniazid; Nutritio | 1981 |
Isoniazid toxicity as a cause of peripheral neuropathy. Case presentation and discussion.
Topics: Female; Foot Diseases; Humans; Isoniazid; Middle Aged; Peripheral Nervous System Diseases; Pyridoxin | 1981 |
Morphometric evaluation of degenerative and regenerative changes in isoniazid-induced neuropathy.
Topics: Animals; Axons; Isoniazid; Male; Microscopy, Electron; Nerve Degeneration; Peripheral Nerves; Periph | 1983 |
Positive tuberculin skin tests and isoniazid chemoprophylaxis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Isoniazid; Middle Aged; Neuritis; Nur | 1984 |
The effects of chronic isoniazid intoxication on motor end plate sprouting in rat sternocostalis muscle and on responses to partial denervation and local botulinum toxin.
Topics: Animals; Botulinum Toxins; Cystathionine; Cysteine; Cystine; Drug Interactions; Female; Glutathione; | 1984 |
Pyridoxine and isonex.
Topics: Humans; Isoniazid; Peripheral Nervous System Diseases; Pyridoxine | 1993 |
Demonstration of slow acetylator genotype of N-acetyltransferase in isoniazid neuropathy using an archival hematoxylin and eosin section of a sural nerve biopsy specimen.
Topics: Acetylation; Alleles; Antitubercular Agents; Arylamine N-Acetyltransferase; Base Sequence; Biopsy; D | 1996 |
Increased incidence of peripheral neuropathy with co-administration of stavudine and isoniazid in HIV-infected individuals.
Topics: Adult; Aged; Anti-HIV Agents; Antitubercular Agents; Drug Therapy, Combination; HIV Infections; Huma | 2000 |
Successful generation of peripheral neuropathy with onion-bulb formation in the macrophage scavenger receptor classA knockout mouse treated with isoniazid.
Topics: Animals; Antitubercular Agents; Female; Injections, Intraperitoneal; Isoniazid; Mice; Mice, Inbred A | 2000 |
Method for conducting sensitivity analysis.
Topics: Biometry; Humans; Isoniazid; Models, Statistical; Peripheral Nervous System Diseases; Polymorphism, | 1999 |
[Polyneuropathies as a diagnostic and therapeutic task].
Topics: Adult; Alcoholic Intoxication; Botulism; Child; Diabetic Neuropathies; Diagnosis, Differential; Diph | 1977 |
Studies on the early changes in acute isoniazid neuropathy in the rat.
Topics: Acute Disease; Animals; Axons; Endoplasmic Reticulum; Isoniazid; Microscopy, Electron; Microtubules; | 1979 |
[Surveillance and complications of antituberculosis chemotherapy].
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Hypersensitivity | 1979 |
The distribution of degenerative changes in INH neuropathy. Further evidence for focal axonal lesions.
Topics: Animals; Axons; Isoniazid; Male; Microscopy, Electron; Nerve Degeneration; Nerve Regeneration; Perip | 1979 |
Isoniazid induced neuropathy in slow versus rapid acetylators: an electrophysiological study.
Topics: Acetylation; Action Potentials; Adolescent; Adult; Aged; Child; Electromyography; Female; Humans; Is | 1992 |
Isoniazid induced peripheral neuropathy.
Topics: Humans; Isoniazid; Peripheral Nervous System Diseases; Pyridoxine; Sensation Disorders | 1992 |
Peripheral neuropathy in HIV patient after isoniazid therapy initiated.
Topics: Adult; HIV Seropositivity; Humans; Isoniazid; Male; Peripheral Nervous System Diseases | 1991 |
Exacerbation of isoniazid induced peripheral neuropathy by pyridoxine.
Topics: Acetylation; Arthritis, Rheumatoid; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Mycobacterium | 1990 |
Neurotoxicity of antituberculous drugs in a patient without active tuberculosis.
Topics: Antitubercular Agents; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Optic Atrophy; Peripheral N | 1988 |
Isoniazid, rifampin, and hepatotoxicity.
Topics: Acetylation; Asian; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug Interactions; Hu | 1986 |
Remodelling of nerve structure in experimental isoniazid neuropathy in the rat.
Topics: Animals; Isoniazid; Male; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Sciatic Ne | 1986 |
The myenteric plexus in drug-induced neuropathy.
Topics: Animals; Ganglia, Autonomic; Injections, Intraperitoneal; Injections, Intravenous; Intestine, Large; | 1967 |
[Supernumerary schwann cells during remyelination of regenerated and segmentally demyelinated axons in peripheral nerves].
Topics: Animals; Demyelinating Diseases; Drug Hypersensitivity; Isoniazid; Microscopy, Electron; Myelin Shea | 1968 |
[Relations between polyneuropathies produced by certain modern drugs, by malabsorption and by malnutrition].
Topics: Animals; Isoniazid; Malabsorption Syndromes; Nitrofurans; Peripheral Nervous System Diseases; Polyne | 1969 |
Peripheral neuritis after long-term isoniazid.
Topics: Aged; Humans; Isoniazid; Male; Neuritis; Peripheral Nervous System Diseases; Tuberculosis, Pulmonary | 1966 |
Mast cells in INH-induced neuropathy of the rat.
Topics: Animals; Capillary Permeability; Cytoplasmic Granules; Injections, Intraperitoneal; Isoniazid; Mast | 1968 |
Studies on vascular permeability in peripheral nerves. 3. Permeability changes of vasa nervorum and exudation of serum albumin in INH-induced neuropathy of the rat.
Topics: Animals; Blood Vessels; Isoniazid; Nerve Degeneration; Peripheral Nerves; Peripheral Nervous System | 1968 |
Toxic chemicals and peripheral neuropathy: clinical and epidemiological features.
Topics: Acrylates; Carbon Disulfide; Diagnosis, Differential; Herbicides; Humans; Isoniazid; Lead Poisoning; | 1969 |
[Ultrastructure of unmyelinated(Remak) nerve fibers in isoniazid neuropathy].
Topics: Animals; Axons; Isoniazid; Microscopy, Electron; Microscopy, Phase-Contrast; Mitochondria; Nerve Deg | 1970 |
Isoniazid neuropathy in man: quantitative electron microscope study.
Topics: Adult; Aged; Biopsy; Demyelinating Diseases; Humans; Isoniazid; Microscopy, Electron; Middle Aged; N | 1970 |
[The pathogenesis of INH-neuropathy. I. Fine structural similarities and differences to wallerian degeneration].
Topics: Animals; Edema; Endoplasmic Reticulum; Isoniazid; Microscopy, Electron; Microscopy, Phase-Contrast; | 1970 |
[Drug-induced polyneuropathy].
Topics: Abnormalities, Drug-Induced; Adult; Animals; Drug-Related Side Effects and Adverse Reactions; Female | 1970 |
Additive toxicity of vincristine and other drugs for the peripheral nervous system. Three case reports.
Topics: Adult; Asparaginase; Female; Humans; Isoniazid; Male; Middle Aged; Neoplasms; Peripheral Nerves; Per | 1971 |
Conduction in unmyelinated fibres in experimental neuropathy.
Topics: Acrylamides; Action Potentials; Animals; Disease Models, Animal; Electric Stimulation; Ganglia, Spin | 1972 |
Isoniazid: a review with emphasis on adverse effects.
Topics: Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Desensitization, Immunologic; Drug Hypers | 1972 |
Peripheral neuropathy secondary to isoniazid-induced pyridoxine deficiency.
Topics: Humans; Isoniazid; Male; Middle Aged; Peripheral Nervous System Diseases; Pyridoxine; Vitamin B 6 De | 1972 |
Sensory conduction in peroneal and posterior tibial nerves using averaging techniques.
Topics: Action Potentials; Adolescent; Adult; Aged; Computers, Analog; Diabetic Neuropathies; Electric Stimu | 1973 |
Isoniazid as a cause of neuropathy and sideroblastic anaemia.
Topics: Aged; Anemia, Sideroblastic; Humans; Isoniazid; Male; Peripheral Nervous System Diseases; Tuberculos | 1973 |
[Clinical relevance of photosensitivity in psychiatric EEG diagnosis].
Topics: Bipolar Disorder; Brain; Electroencephalography; Epilepsy; Humans; Isoniazid; Light; Mental Disorder | 1974 |
[Peripheral neuropathy caused by drug in toxication--direct invasion by drugs and ultrastructural changes of the tissue].
Topics: Animals; Chloramphenicol; Ethambutol; Iodine; Isoniazid; Mice; Microscopy, Electron; Peripheral Nerv | 1974 |