isoniazid has been researched along with Neutropenia in 6 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixteen patients with TB-HIV co-infection received rifabutin 300 mg QD in combination with tuberculosis chemotherapy (initially pyrazinamide, isoniazid and ethambutol then only isoniazid), and were then randomized to receive isoniazid and LPV/r based ART with rifabutin 150 mg tiw or rifabutin 150 mg daily." | 9.19 | Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy. ( Connolly, C; Harries, A; Kellerman, T; Lienhardt, C; McIlleron, H; Naiker, S; Pym, A; Reddy, T; Wiesner, L, 2014) |
| "Sixteen patients with TB-HIV co-infection received rifabutin 300 mg QD in combination with tuberculosis chemotherapy (initially pyrazinamide, isoniazid and ethambutol then only isoniazid), and were then randomized to receive isoniazid and LPV/r based ART with rifabutin 150 mg tiw or rifabutin 150 mg daily." | 5.19 | Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy. ( Connolly, C; Harries, A; Kellerman, T; Lienhardt, C; McIlleron, H; Naiker, S; Pym, A; Reddy, T; Wiesner, L, 2014) |
| "Neutropenia is a rare complication of anti-tuberculous therapy and is usually due to a single agent, most frequently isoniazid." | 3.72 | G-CSF enables completion of tuberculosis therapy associated with iatrogenic neutropenia. ( Cormican, LJ; Milburn, HJ; Schey, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naiker, S | 1 |
| Connolly, C | 1 |
| Wiesner, L | 1 |
| Kellerman, T | 1 |
| Reddy, T | 1 |
| Harries, A | 1 |
| McIlleron, H | 1 |
| Lienhardt, C | 1 |
| Pym, A | 1 |
| HANSEN, JE | 1 |
| WADE, AB | 1 |
| STAFFORD, JL | 1 |
| Cormican, LJ | 1 |
| Schey, S | 1 |
| Milburn, HJ | 1 |
| Jenkins, PF | 1 |
| Williams, TD | 1 |
| Campbell, IA | 1 |
| Cornet, A | 1 |
| Cornu, P | 1 |
| Dubrisay, J | 1 |
| Barbier, JP | 1 |
| Hirsch, JF | 1 |
| Carnot, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in the Treatment of Tuberculosis Patient With HIV Infection in South Africa: A Phase II Trial[NCT00640887] | Phase 2 | 48 participants (Anticipated) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for isoniazid and Neutropenia
| Article | Year |
|---|---|
Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Antibiotics, Antitubercular; Black People; Coinfection; Cross-Over Studies; | 2014 |
5 other studies available for isoniazid and Neutropenia
| Article | Year |
|---|---|
Hypersensitivity to isoniazid with neutropenia and thrombocytopenia.
Topics: Agranulocytosis; Humans; Isoniazid; Leukopenia; Neutropenia; Thrombocytopenia | 1961 |
CYCLICAL NEUTROPENIA.
Topics: Agranulocytosis; Ecchymosis; Gingivitis; Gingivitis, Necrotizing Ulcerative; Humans; Isoniazid; Lymp | 1963 |
G-CSF enables completion of tuberculosis therapy associated with iatrogenic neutropenia.
Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Ethambutol; Granulocyte Colony-Stimulatin | 2004 |
Neutropenia with each standard antituberculosis drug in the same patient.
Topics: Aged; Agranulocytosis; Antibiotics, Antitubercular; Ethambutol; Humans; Isoniazid; Leukocyte Count; | 1980 |
[Hematopoietic tuberculosis].
Topics: Bone Marrow; Bone Marrow Examination; Cholestasis; Erythema; Ethambutol; Humans; Isoniazid; Leukopen | 1974 |