Compounds > isoniazid
Page last updated: 2024-10-29

isoniazid and Nervous System Disorders

isoniazid has been researched along with Nervous System Disorders in 44 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Research Excerpts

ExcerptRelevanceReference
"Thirty nine cases of borderline tuberculoid leprosy having nerve abscesses (15 with sinuses) were treated with daily dose of rifampicin and isoniazid for six months along with standard multidrug therapy."7.69Rifampicin and isoniazid in the treatment of leprous nerve abscesses. ( Husain, S; Malaviya, GN; Mishra, B, 1997)
" - The LTT was performed with isoniazid and rifampicin in 15 tuberculosis and 2 MOTT (Mycobacteria other than tuberculosis)-infection patients who suffered drug reactions, in 23 patients without any adverse reactions, in 7 controls previously exposed to antituberculous drugs, and in 14 controls who had never been exposed."3.70Lymphocyte transformation test for the evaluation of adverse effects of antituberculous drugs. ( Greinert, U; Müller-Quernheim, J; Schlaak, M; Schreiber, J; Zissel, G, 1999)
"Over the past 10 years the reported incidence of acute isoniazid (INH)-related poisonings has increased, with 507 cases reported in 1996."3.70Acute isoniazid exposures and antidote availability. ( Linakis, JG; Santucci, KA; Shah, BR, 1999)
"Thirty nine cases of borderline tuberculoid leprosy having nerve abscesses (15 with sinuses) were treated with daily dose of rifampicin and isoniazid for six months along with standard multidrug therapy."3.69Rifampicin and isoniazid in the treatment of leprous nerve abscesses. ( Husain, S; Malaviya, GN; Mishra, B, 1997)
"Tuberculomas are best treated medically."2.37CNS tuberculosis. ( Des Prez, RM; Sheller, JR, 1986)
"Possible toxic side-effects of antituberculous chemotherapy are studied in 718 children affected with pulmonary tuberculosis."1.27[Toxicity in the current treatment of pulmonary tuberculosis in children]. ( Alcáide Megías, J; Altet Gómez, MN; Boque Genovard, MA, 1984)
"gamma-Aminobutyric acid (GABA) was measured in CSF as such and following acid hydrolysis by the ion-exchange/fluorometric method."1.27Free and conjugated GABA in human cerebrospinal fluid: effect of degenerative neurologic diseases and isoniazid. ( Manyam, BV; Tremblay, RD, 1984)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199038 (86.36)18.7374
1990's4 (9.09)18.2507
2000's2 (4.55)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kittisupamongkol, W1
LETAILLEUR, M1
SCHMIDT, P1
PETROVICKY, O1
BROZ, J1
NICK, J3
Carlson, HB1
Anthony, EM1
Russell, WF1
Middlebrook, G1
ANQUEZ, L2
CONTAMIN, F2
LEMPERIERE, T2
DIXON, GJ2
ROBERTS, GB2
TYRRELL, WF2
BRAGE, D1
CHLOPICKI, L1
PALACIOS, E1
KAHAN, A1
KAHAN, IL1
BENKO, A1
BONDAREV, IM1
PALMER, AC1
NOEL, PR1
BLOEDORN, H1
RAUTERBERG, W1
GUNELLA, P1
Lysov, AV1
Mordyk, AV1
Zatvornitskiĭ, VA1
Kondria, AV1
Carlton, WW1
Altet Gómez, MN1
Alcáide Megías, J1
Boque Genovard, MA1
Manyam, BV1
Tremblay, RD1
Romá, J1
Soria, B1
Siskind, MS1
Thienemann, D1
Kirlin, L1
Husain, S1
Mishra, B1
Malaviya, GN1
Schreiber, J1
Zissel, G1
Greinert, U1
Schlaak, M1
Müller-Quernheim, J1
Santucci, KA1
Shah, BR1
Linakis, JG1
Newton, RW1
Sobue, I1
Daun, H1
Sanders, WE1
Sanders, CC1
Cavanagh, JB1
Naess, K1
Doğanay, M1
Bakir, M1
Dökmetaş, I1
Bunker, E1
Friede, RL1
Sheller, JR1
Des Prez, RM1
Ohnishi, A1
Chua, CL1
Kuroiwa, Y1
Bammer, HG1
Schröder, JM1
Tateishi, J1
Weinstein, L1
Dalton, AC1
Osuntokun, BO1
Adeuja, AO1
Familusi, JB1
Wasik, A1
Palleschi, M1

Reviews

8 reviews available for isoniazid and Nervous System Disorders

ArticleYear
Isoniazid-induced neurotoxicity in chronic dialysis patients: report of three cases and a review of the literature.
    Nephron, 1993, Volume: 64, Issue:2

    Topics: Aged; Aged, 80 and over; Female; Humans; Isoniazid; Kidney Failure, Chronic; Male; Middle Aged; Nerv

1993
[Exogenous toxic neuropathy (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1976, Aug-10, Volume: 65, Issue:8

    Topics: Acrylamides; Adolescent; Adult; Aged; Aldrin; Carbon Disulfide; Chloramphenicol; Clioquinol; DDT; Di

1976
Toxicity of antibacterial agents: mechanism of action on mammalian cells.
    Annual review of pharmacology and toxicology, 1979, Volume: 19

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Carbohydrate Metabolism; Cel

1979
The 'dying back' process. A common denominator in many naturally occurring and toxic neuropathies.
    Archives of pathology & laboratory medicine, 1979, Volume: 103, Issue:13

    Topics: Acrylamides; Animals; Arsenic Poisoning; Carbon Disulfide; Humans; Isoniazid; Nerve Degeneration; Ne

1979
CNS tuberculosis.
    Neurologic clinics, 1986, Volume: 4, Issue:1

    Topics: Biopsy; Cerebral Ventricles; Cerebrospinal Fluid; Ethambutol; Humans; Hyaluronoglucosaminidase; Ison

1986
[Neurological aspects of the vitamin B complex].
    Zeitschrift fur Neurologie, 1972, Volume: 202, Issue:3

    Topics: Alcoholism; Anticonvulsants; Cyanides; Deficiency Diseases; Electroencephalography; Erythrocytes; Fo

1972
Host determinants of response to antimicrobial agents.
    The New England journal of medicine, 1968, Sep-05, Volume: 279, Issue:10

    Topics: Anemia, Hypochromic; Anemia, Pernicious; Anti-Infective Agents; Cystic Fibrosis; Diabetes Complicati

1968
Vitamin B6 deficiency following isoniazid therapy.
    Nutrition reviews, 1968, Volume: 26, Issue:10

    Topics: Humans; Isoniazid; Nervous System Diseases; Tuberculosis; Vitamin B 6 Deficiency

1968

Other Studies

36 other studies available for isoniazid and Nervous System Disorders

ArticleYear
Pyridoxine in pregnant women receiving antituberculous drugs.
    BJOG : an international journal of obstetrics and gynaecology, 2009, Volume: 116, Issue:9

    Topics: Antitubercular Agents; Female; Humans; Isoniazid; Nervous System Diseases; Pregnancy; Pregnancy Comp

2009
[Mental and neurological disorders caused by toxic effects of isonicotinic acid hydrazide].
    Annales medico-psychologiques, 1953, Volume: 111, Issue:1 2

    Topics: Isoniazid; Mental Disorders; Nervous System Diseases; Niacin; Nicotinic Acids; Psychoses, Substance-

1953
[Neurological complications following isonicotinic acid hydrazide therapy of pulmonary tuberculosis].
    Casopis lekaru ceskych, 1956, Jan-20, Volume: 95, Issue:3

    Topics: Isoniazid; Nervous System; Nervous System Diseases; Niacin; Nicotinic Acids; Tuberculosis; Tuberculo

1956
[Phenomenon of perseveration of painful and thermal sensations in toxic polyneuritis caused by isoniazid].
    Revue neurologique, 1955, Volume: 93, Issue:5

    Topics: Isoniazid; Nervous System Diseases; Neuritis; Niacin; Nicotinic Acids; Pain

1955
Prophylaxis of isoniazid neuropathy with pyridoxine.
    The New England journal of medicine, 1956, 07-19, Volume: 255, Issue:3

    Topics: Humans; Isomerism; Isoniazid; Nervous System Diseases; Niacin; Nicotinic Acids; Peripheral Nervous S

1956
[Unilateral sensory and motor neurological manifestations secondary to therapeutic use of isoniazid. Is it correct to retain the concept of polyneuritis caused by isonicotinic acid hydrazid?].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1956, Oct-12, Volume: 72, Issue:24-25

    Topics: Databases, Genetic; Humans; Isoniazid; Isonicotinic Acids; Nervous System Diseases; Neuritis

1956
[Unilateral sensory and motor neurological manifestations secondary to therapeutic use of isoniazid. Is it correct to retain the concept of polyneuritis caused by isonicotinic acid hydrazid?].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1956, Oct-12, Volume: 72, Issue:24-25

    Topics: Databases, Genetic; Humans; Isoniazid; Isonicotinic Acids; Nervous System Diseases; Neuritis

1956
[Unilateral sensory and motor neurological manifestations secondary to therapeutic use of isoniazid. Is it correct to retain the concept of polyneuritis caused by isonicotinic acid hydrazid?].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1956, Oct-12, Volume: 72, Issue:24-25

    Topics: Databases, Genetic; Humans; Isoniazid; Isonicotinic Acids; Nervous System Diseases; Neuritis

1956
[Unilateral sensory and motor neurological manifestations secondary to therapeutic use of isoniazid. Is it correct to retain the concept of polyneuritis caused by isonicotinic acid hydrazid?].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1956, Oct-12, Volume: 72, Issue:24-25

    Topics: Databases, Genetic; Humans; Isoniazid; Isonicotinic Acids; Nervous System Diseases; Neuritis

1956
The relationship of neuropathy to the treatment of tuberculosis with isoniazid.
    Scottish medical journal, 1956, Volume: 1, Issue:11

    Topics: Humans; Isoniazid; Nervous System Diseases; Tuberculosis

1956
The relationship of neuropathy to the treatment of tuberculosis with isoniazid.
    Scottish medical journal, 1956, Volume: 1, Issue:11

    Topics: Humans; Isoniazid; Nervous System Diseases; Tuberculosis

1956
The relationship of neuropathy to the treatment of tuberculosis with isoniazid.
    Scottish medical journal, 1956, Volume: 1, Issue:11

    Topics: Humans; Isoniazid; Nervous System Diseases; Tuberculosis

1956
The relationship of neuropathy to the treatment of tuberculosis with isoniazid.
    Scottish medical journal, 1956, Volume: 1, Issue:11

    Topics: Humans; Isoniazid; Nervous System Diseases; Tuberculosis

1956
[Therapeutic tests of various neurological syndromes with isoniazid].
    Medicina panamericana, 1958, Mar-15, Volume: 10, Issue:6

    Topics: Databases, Genetic; Humans; Isoniazid; Nervous System Diseases; Syndrome

1958
[On the neurological disorders during treatment with isoniazid].
    Revue neurologique, 1959, Volume: 100

    Topics: Humans; Isoniazid; Nervous System; Nervous System Diseases

1959
[NEUROLOGIC COMPLICATIONS OF INFECTIOUS DISEASES].
    Revista chilena de pediatria, 1963, Volume: 34

    Topics: Adrenocorticotropic Hormone; Child; Communicable Diseases; Humans; Immunization; Infant; Isoniazid;

1963
ACQUIRED ACANTHOCYTOSIS AND MYELOPHTHISIS IN A CASE OF EALES'S DISEASE.
    The British journal of ophthalmology, 1963, Volume: 47

    Topics: Abetalipoproteinemia; Clinical Laboratory Techniques; Drug Therapy; Erythrocytes; Eye Diseases; Huma

1963
[EXPERIMENTAL STUDY OF THE HEALING MECHANISM OF TUBERCULOUS CAVERNS].
    Problemy tuberkuleza, 1964, Volume: 42

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Caves; Dogs; Electroencephalography; Isoniazid; Lung; Ner

1964
NEUROPATHOLOGICAL EFFECTS OF DOSING DOGS WITH ISONICOTINIC HYDRAZIDE AND WITH ITS METHANOSULPHONATE DERIVATIVE.
    Nature, 1965, Jan-30, Volume: 205

    Topics: Brain Diseases; Brain Edema; Capillaries; Cerebrovascular Circulation; Dogs; Hyperplasia; Isoniazid;

1965
[Vitamin B12 treatment of neurotoxic side effects of isoniazid therapy].
    Deutsches medizinisches Journal, 1955, Feb-15, Volume: 6, Issue:3-4

    Topics: Corrinoids; Isoniazid; Nervous System Diseases; Niacin; Nicotinic Acids; Vitamin B 12; Vitamin B Com

1955
[Treatment of neurological complications during isonicotinic acid hydrazide therapy].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1955, Apr-15, Volume: 10, Issue:8

    Topics: Isomerism; Isoniazid; Nervous System Diseases; Niacin; Nicotinic Acids

1955
[First impressions of use of isonicotinic acid hydrazide in pulmonary tuberculosis bedridden subjects in the Rasori Sanatorium].
    Giornale di clinica medica, 1952, Volume: 33, Issue:5

    Topics: Isoniazid; Nervous System Diseases; Niacin; Nicotinic Acids; Tuberculosis; Tuberculosis, Pulmonary

1952
[Adverse neurotoxic reactions of chemotherapy for tuberculosis and their treatment].
    Problemy tuberkuleza i boleznei legkikh, 2006, Issue:9

    Topics: Adult; Antitubercular Agents; Female; Follow-Up Studies; Glutamates; Humans; Incidence; Intercellula

2006
Neural toxicity of isonicotinic acid hydrazide (isoniazid) for chickens.
    Avian diseases, 1967, Volume: 11, Issue:2

    Topics: Animals; Cerebellum; Hematocrit; Isoniazid; Kidney; Liver; Male; Myocardium; Nervous System Diseases

1967
[Toxicity in the current treatment of pulmonary tuberculosis in children].
    Anales espanoles de pediatria, 1984, Volume: 20, Issue:1

    Topics: Adolescent; Antitubercular Agents; Blood Coagulation Disorders; Chemical and Drug Induced Liver Inju

1984
Free and conjugated GABA in human cerebrospinal fluid: effect of degenerative neurologic diseases and isoniazid.
    Brain research, 1984, Jul-30, Volume: 307, Issue:1-2

    Topics: Adult; Age Factors; Aged; Cerebellar Ataxia; Dementia; Epilepsy; gamma-Aminobutyric Acid; Humans; Hu

1984
Isonicotinic acid hydrazide: early effects on peripheral nerve conduction velocity.
    Experientia, 1984, Apr-15, Volume: 40, Issue:4

    Topics: Animals; Body Weight; Isoniazid; Kinetics; Nervous System Diseases; Neural Conduction; Peripheral Ne

1984
Rifampicin and isoniazid in the treatment of leprous nerve abscesses.
    Acta leprologica, 1997, Volume: 10, Issue:3

    Topics: Abscess; Adult; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isoniazid; Leprostatic

1997
Lymphocyte transformation test for the evaluation of adverse effects of antituberculous drugs.
    European journal of medical research, 1999, Feb-25, Volume: 4, Issue:2

    Topics: Adult; Anaphylaxis; Anti-Bacterial Agents; Antitubercular Agents; Bromodeoxyuridine; Cells, Cultured

1999
Acute isoniazid exposures and antidote availability.
    Pediatric emergency care, 1999, Volume: 15, Issue:2

    Topics: Acute Disease; Antidotes; Antitubercular Agents; Child; Drug Storage; Emergency Medicine; Emergency

1999
Side effects of drugs used to treat tuberculosis.
    Scottish medical journal, 1975, Volume: 20, Issue:2

    Topics: Aminosalicylic Acids; Animals; Antitubercular Agents; Capreomycin; Chemical and Drug Induced Liver I

1975
[Polyneuropathies as a diagnostic and therapeutic task].
    Fortschritte der Medizin, 1977, Apr-14, Volume: 95, Issue:14

    Topics: Adult; Alcoholic Intoxication; Botulism; Child; Diabetic Neuropathies; Diagnosis, Differential; Diph

1977
[Isoniazid; adverse effects].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Sep-30, Volume: 95, Issue:27

    Topics: Gastrointestinal Diseases; Humans; Isoniazid; Nervous System Diseases; Pyridoxine

1975
Treatment of tuberculous meningitis in adults with a combination of isoniazid, rifampicin and streptomycin: a prospective study.
    Scandinavian journal of infectious diseases, 1989, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Middle Ag

1989
Changes in the histograms of nerves resulting from growth and various modalities of damage. A computer simulation.
    Acta neuropathologica, 1989, Volume: 78, Issue:5

    Topics: Animals; Computer Simulation; Humans; Isoniazid; Nerve Fibers; Nerve Regeneration; Nervous System; N

1989
Axonal degeneration distal to the site of accumulation of vesicular profiles in the myelinated fiber axon in experimental isoniazid neuropathy.
    Acta neuropathologica, 1985, Volume: 67, Issue:3-4

    Topics: Animals; Axons; Histological Techniques; Isoniazid; Male; Microscopy, Electron; Nerve Degeneration;

1985
[The pathogenesis of INH-neuropathy. II. Phase and electron microscopic studies of spinal cord, spinal ganglia and muscle spindles].
    Acta neuropathologica, 1970, Volume: 16, Issue:4

    Topics: Animals; Ganglia, Spinal; Isoniazid; Microscopy, Electron; Microscopy, Phase-Contrast; Mitochondria;

1970
Comparative study of neurotoxicity of clioquinol, ethambutol, isoniazid and chloramphenicol in dogs.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:1

    Topics: Abdomen; Administration, Oral; Animals; Axons; Chloramphenicol; Clioquinol; Dogs; Ethambutol; Isonia

1974
Tuberculous meningitis in Nigerians. A study of 194 patients.
    Tropical and geographical medicine, 1971, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Femal

1971
Mental disorders caused by isonicotinic acid hydrazide (INH) in the course of treatment of pulmonary tuberculosis.
    Polish medical journal, 1970, Volume: 9, Issue:6

    Topics: Affective Symptoms; Age Factors; Alcoholism; Central Nervous System Diseases; Delirium; Delusions; E

1970
Vitamins of the B complex.
    British medical journal, 1968, Dec-14, Volume: 4, Issue:5632

    Topics: Aged; Alcoholism; Anemia, Hypochromic; Avitaminosis; Beriberi; Heart Failure; Humans; Isoniazid; Ner

1968
[Collateral effects of isonicotinic acid hydrazide].
    La Clinica terapeutica, 1966, Volume: 39, Issue:6

    Topics: Blood Coagulation Disorders; Drug Hypersensitivity; Humans; Isoniazid; Liver Diseases; Nervous Syste

1966