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isoniazid and Nerve Degeneration

isoniazid has been researched along with Nerve Degeneration in 20 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"Cerebellar changes have been reported in relationship to epilepsy alone as well as to phenytoin therapy for the control of seizures."3.65Phenytoin-related cerebellar degeneration without seizures. ( Rapport, RL; Shaw, CM, 1977)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199018 (90.00)18.7374
1990's1 (5.00)18.2507
2000's0 (0.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SCHLAEPFER, WW1
HAGER, H1
Chua, CL2
Ohnishi, A2
Tateishi, J1
Kuroiwa, Y2
Cavanagh, JB4
Gysbers, MF1
Schmued, L1
Slikker, W1
Jacobs, JM1
Miller, RH1
Rapport, RL1
Shaw, CM1
Sea, CP1
Peterson, RG1
Thomas, PK1
Olsson, Y1
Schröder, JM2
Hopkins, AP1
Lambert, EH1
Castellano, MA1
Tórtora, JL1
Germino, NI1
Rama, F1
Ohanian, C1
Lampert, PW1
Schochet, SS1
Hildebrand, J1
Joffroy, A1
Coërs, C1
Chen, FC1
Kyu, MH1
Ridley, A1
Tomczyk, S1
Buzgariu, W1
Perruchoud, C1
Fisher, K1
Austad, S1
Galliot, B1
Davis, LE1
Bursztajn, S1

Reviews

2 reviews available for isoniazid and Nerve Degeneration

ArticleYear
The 'dying back' process. A common denominator in many naturally occurring and toxic neuropathies.
    Archives of pathology & laboratory medicine, 1979, Volume: 103, Issue:13

    Topics: Acrylamides; Animals; Arsenic Poisoning; Carbon Disulfide; Humans; Isoniazid; Nerve Degeneration; Ne

1979
The morphological basis for alterations in nerve conduction in peripheral neuropathy.
    Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:3

    Topics: Amyloidosis; Animals; Axons; Beriberi; Cresols; Demyelinating Diseases; Diabetic Neuropathies; Diffu

1971

Other Studies

18 other studies available for isoniazid and Nerve Degeneration

ArticleYear
ULTRASTRUCTURAL STUDIES OF INH-INDUCED NEUROPATHY IN RATS. 3. REPAIR AND REGENERATION.
    The American journal of pathology, 1964, Volume: 45

    Topics: Axons; Electrons; Isoniazid; Microscopy; Microscopy, Electron; Microscopy, Phase-Contrast; Myelin Sh

1964
Morphometric evaluation of degenerative and regenerative changes in isoniazid-induced neuropathy.
    Acta neuropathologica, 1983, Volume: 60, Issue:3-4

    Topics: Animals; Axons; Isoniazid; Male; Microscopy, Electron; Nerve Degeneration; Peripheral Nerves; Periph

1983
"Dying back" above a nerve ligature produced by acrylamide.
    Acta neuropathologica, 1980, Volume: 51, Issue:3

    Topics: Acrylamides; Animals; Dose-Response Relationship, Drug; Female; Hexanones; Isoniazid; Ketones; Ligat

1980
Black-gold: a simple, high-resolution histochemical label for normal and pathological myelin in brain tissue sections.
    Brain research, 1999, Aug-07, Volume: 837, Issue:1-2

    Topics: Animals; Axonal Transport; Brain; Cerebral Cortex; Coloring Agents; Fluorescent Dyes; Histocytochemi

1999
The distribution of degenerative changes in INH neuropathy. Further evidence for focal axonal lesions.
    Acta neuropathologica, 1979, Volume: 48, Issue:1

    Topics: Animals; Axons; Isoniazid; Male; Microscopy, Electron; Nerve Degeneration; Nerve Regeneration; Perip

1979
Phenytoin-related cerebellar degeneration without seizures.
    Annals of neurology, 1977, Volume: 2, Issue:5

    Topics: Cerebellum; Epilepsy; Female; Gliosis; Humans; Isoniazid; Middle Aged; Nerve Degeneration; Neuroglia

1977
Ultrastructure and biochemistry of myelin after isoniazid-induced nerve degeneration in rats.
    Experimental neurology, 1975, Volume: 48, Issue:2

    Topics: Animals; Electrophoresis; Isoniazid; Male; Microscopy, Electron; Myelin Sheath; Nerve Degeneration;

1975
Axonal degeneration distal to the site of accumulation of vesicular profiles in the myelinated fiber axon in experimental isoniazid neuropathy.
    Acta neuropathologica, 1985, Volume: 67, Issue:3-4

    Topics: Animals; Axons; Histological Techniques; Isoniazid; Male; Microscopy, Electron; Nerve Degeneration;

1985
Studies on vascular permeability in peripheral nerves. 3. Permeability changes of vasa nervorum and exudation of serum albumin in INH-induced neuropathy of the rat.
    Acta neuropathologica, 1968, Sep-02, Volume: 11, Issue:2

    Topics: Animals; Blood Vessels; Isoniazid; Nerve Degeneration; Peripheral Nerves; Peripheral Nervous System

1968
[Ultrastructure of unmyelinated(Remak) nerve fibers in isoniazid neuropathy].
    Acta neuropathologica, 1970, Volume: 15, Issue:2

    Topics: Animals; Axons; Isoniazid; Microscopy, Electron; Microscopy, Phase-Contrast; Mitochondria; Nerve Deg

1970
[The pathogenesis of INH-neuropathy. I. Fine structural similarities and differences to wallerian degeneration].
    Acta neuropathologica, 1970, Volume: 16, Issue:4

    Topics: Animals; Edema; Endoplasmic Reticulum; Isoniazid; Microscopy, Electron; Microscopy, Phase-Contrast;

1970
Conduction in unmyelinated fibres in experimental neuropathy.
    Journal of neurology, neurosurgery, and psychiatry, 1972, Volume: 35, Issue:2

    Topics: Acrylamides; Action Potentials; Animals; Disease Models, Animal; Electric Stimulation; Ganglia, Spin

1972
The effects of isonicotinic acid hydrazide on the early chick embryo.
    Journal of embryology and experimental morphology, 1973, Volume: 29, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Epithelium; Isoniazid; Nerve Degeneration; Neuro

1973
Electron microscopic observations on experimental spongy degeneration of the cerebellar white matter.
    Journal of neuropathology and experimental neurology, 1968, Volume: 27, Issue:2

    Topics: Animals; Axons; Brain Stem; Cerebellar Ataxia; Cerebellum; Demyelinating Diseases; Ducks; Encephalom

1968
Myoneural changes in experimental isoniazid neuropathy. Electrophysiological and histological study.
    Archives of neurology, 1968, Volume: 19, Issue:1

    Topics: Action Potentials; Animals; Electric Stimulation; Isoniazid; Motor Activity; Muscles; Muscular Atrop

1968
The experimental neuropathy in rats caused by p-bromophenylacetylurea.
    Journal of neurology, neurosurgery, and psychiatry, 1968, Volume: 31, Issue:5

    Topics: Animals; Brain; Extremities; Female; Gliosis; Guinea Pigs; Isoniazid; Male; Motor Neurons; Nerve Deg

1968
Loss of Neurogenesis in Aging Hydra.
    Developmental neurobiology, 2019, Volume: 79, Issue:5

    Topics: Aging; Animals; Cold Temperature; Eating; Gene Expression; Hydra; Movement; Nerve Degeneration; Neur

2019
The role of the nervous system in regeneration, growth and cell differentiation in Hydra. II. Ultrastructural study of nerve cell elements during hypostomal regeneration.
    Cell and tissue research, 1974, Jul-12, Volume: 150, Issue:2

    Topics: Animals; Cell Differentiation; Cell Nucleus; Cytoplasmic Granules; Endoplasmic Reticulum; Extracellu

1974