isoniazid has been researched along with Liver Steatosis in 16 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoniazid (INH) treatment can cause serious liver injury and autoimmunity." | 1.40 | Paradoxical attenuation of autoimmune hepatitis by oral isoniazid in wild-type and N-acetyltransferase-deficient mice. ( Cai, P; Grant, DM; Metushi, IG; Uetrecht, J; Vega, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (50.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Song, Y | 1 |
| Qu, X | 1 |
| Tao, L | 1 |
| Gao, H | 1 |
| Zhang, Y | 1 |
| Zhai, J | 1 |
| Gong, J | 1 |
| Hu, T | 1 |
| Zhang, G | 1 |
| Chen, L | 1 |
| Wen, Y | 1 |
| Rao, Z | 1 |
| Wei, Y | 1 |
| Wu, X | 1 |
| Metushi, IG | 1 |
| Cai, P | 1 |
| Vega, L | 1 |
| Grant, DM | 1 |
| Uetrecht, J | 1 |
| Church, RJ | 1 |
| Wu, H | 1 |
| Mosedale, M | 1 |
| Sumner, SJ | 1 |
| Pathmasiri, W | 1 |
| Kurtz, CL | 1 |
| Pletcher, MT | 1 |
| Eaddy, JS | 1 |
| Pandher, K | 1 |
| Singer, M | 1 |
| Batheja, A | 1 |
| Watkins, PB | 1 |
| Adkins, K | 1 |
| Harrill, AH | 1 |
| Hassan, HM | 1 |
| Guo, H | 1 |
| Yousef, BA | 1 |
| Guerram, M | 1 |
| Hamdi, AM | 1 |
| Zhang, L | 1 |
| Jiang, Z | 1 |
| MCKENNIS, H | 1 |
| YARD, AS | 1 |
| PAHNELAS, EV | 1 |
| SCHMIDT, B | 1 |
| MODDE, H | 1 |
| Chowdhury, A | 1 |
| Santra, A | 1 |
| Bhattacharjee, K | 1 |
| Ghatak, S | 1 |
| Saha, DR | 1 |
| Dhali, GK | 1 |
| Thaler, H | 1 |
| Sarich, TC | 1 |
| Adams, SP | 1 |
| Zhou, T | 1 |
| Wright, JM | 1 |
| Novaro, GM | 1 |
| Ziegler, HK | 1 |
| Sinazadeh, M | 1 |
| Zimmerman, HJ | 1 |
| Austerhoff, A | 1 |
| Kindler, U | 1 |
| Knop, P | 1 |
| Knieriem, HJ | 1 |
| Sosnowski, W | 1 |
| Rozniecki, J | 1 |
| Tomaszkiewicz, L | 1 |
| Bechcińska, B | 1 |
| Cyperling, I | 1 |
| Schmid, M | 1 |
16 other studies available for isoniazid and Liver Steatosis
| Article | Year |
|---|---|
Exploration of the underlying mechanisms of isoniazid/rifampicin-induced liver injury in mice using an integrated proteomics and metabolomics approach.
Topics: Animals; Chemical and Drug Induced Liver Injury; Fatty Liver; Inflammation; Isoniazid; Liver; Male; | 2022 |
Pyridoxal isonicotinoyl hydrazone inhibition of FXR is involved in the pathogenesis of isoniazid-induced liver injury.
Topics: Animals; Apoptosis; Behavior, Animal; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; | 2020 |
Paradoxical attenuation of autoimmune hepatitis by oral isoniazid in wild-type and N-acetyltransferase-deficient mice.
Topics: Administration, Oral; Animals; Arylamine N-Acetyltransferase; Fatty Liver; Female; Hepatitis, Autoim | 2014 |
A systems biology approach utilizing a mouse diversity panel identifies genetic differences influencing isoniazid-induced microvesicular steatosis.
Topics: Animals; Antitubercular Agents; Cholesterol; Fatty Liver; Female; Gene Expression; Isoniazid; Liver; | 2014 |
Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment.
Topics: Animals; Antitubercular Agents; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cytoch | 2016 |
The production of fatty livers in rabbits by isoniazid and other hydrazine derivatives.
Topics: Animals; Fatty Liver; Hydrazines; Isoniazid; Liver Diseases; Niacin; Nicotinic Acids; Rabbits | 1956 |
[Is there an isoniazid fatty liver?].
Topics: Fatty Liver; Isoniazid; Liver | 1961 |
Mitochondrial oxidative stress and permeability transition in isoniazid and rifampicin induced liver injury in mice.
Topics: Animals; Disease Models, Animal; Fatty Liver; Glutathione; Isoniazid; Liver; Male; Mice; Mice, Inbre | 2006 |
[Liver damage following antituberculous therapy].
Topics: Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Ethambutol; Fatty Liver; Humans; Isoniazi | 1982 |
Isoniazid-induced hepatic necrosis and steatosis in rabbits: absence of effect of gender.
Topics: Animals; Antitubercular Agents; Argininosuccinate Lyase; Fatty Liver; Female; Hypertriglyceridemia; | 1997 |
Isoniazid and nonalcoholic steatohepatitis.
Topics: Adult; Antitubercular Agents; Fatty Liver; Female; Humans; Isoniazid; Liver; Tuberculosis | 1999 |
[Anticonvulsant drugs and liver damage (Author's transl)].
Topics: Adult; Anticonvulsants; Antitubercular Agents; Autopsy; Chemical and Drug Induced Liver Injury; Chol | 1975 |
Liver disease caused by medicinal agents.
Topics: Adrenal Cortex Hormones; Analgesics; Chemical and Drug Induced Liver Injury; Cholestasis; Contracept | 1975 |
[Liver toxicity of combined rifampicin-isoniazid-ethambutol medication (author's transl)].
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bi | 1974 |
[Results of treatment of experimental tuberculosis in guinea pigs with isoniazid or with isoniazid combined with ethambutol, either in continous or in intermittent regimen].
Topics: Animals; Drug Resistance, Microbial; Drug Synergism; Ethambutol; Fatty Liver; Guinea Pigs; Isoniazid | 1970 |
[Hepatotoxic reactions caused by drugs].
Topics: Adolescent; Aminosalicylic Acids; Anabolic Agents; Bilirubin; Carbon Tetrachloride Poisoning; Chemic | 1967 |