isoniazid has been researched along with Liver Neoplasms in 26 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using the on-chip activity assay, hepatocellular carcinoma patients (n = 24), but not hepatitis (n = 24) or liver cirrhosis patients (n = 41), had significantly lower FXIII activities (p < 0." | 1.37 | Rapid determination of blood coagulation factor XIII activity using protein arrays for serodiagnosis of human plasma. ( Ha, KS; Jung, SH; Kim, YM; Kong, DH; Kwon, MH; Suh, IB, 2011) |
| "Liver diseases are common in patients with HIV due to viral hepatitis B and C co-infections, opportunistic infections or malignancies, antiretroviral drugs and drugs for opportunistic infections." | 1.35 | The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala, Uganda. ( Colebunders, R; Feld, J; Kambugu, A; Katabira, E; Katwere, M; Ocama, P; Opio, KC; Piloya, T; Ronald, A; Thomas, D, 2008) |
| "Isoniazid (INH) continues to be a sheet anchor in treatment of tuberculosis, however its chronic administration is known to cause hepatotoxicity through a poorly defined mechanism." | 1.34 | Isoniazid induces oxidative stress, mitochondrial dysfunction and apoptosis in Hep G2 cells. ( Bhadauria, S; Singh, G; Sinha, N; Srivastava, S, 2007) |
| "The human hepatoma line HepG2, the human lymphoblastoid line AHH-1 and the murine lymphoma cells YAC-1 were used as test systems." | 1.32 | In vitro studies on the toxicity of isoniazid in different cell lines. ( Schwab, CE; Tuschl, H, 2003) |
| "National Cancer Institute and two Federal Agencies, seven drugs were listed." | 1.26 | Epidemiological studies of medically used drugs. ( Clemmesen, J; Hjalgrim-Jensen, S, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (53.85) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boechat, N | 2 |
| Ferreira, VF | 1 |
| Ferreira, SB | 1 |
| de Lourdes G Ferreira, M | 1 |
| de C da Silva, F | 1 |
| Bastos, MM | 1 |
| Dos S Costa, M | 1 |
| Lourenço, MC | 1 |
| Pinto, AC | 1 |
| Krettli, AU | 1 |
| Aguiar, AC | 1 |
| Teixeira, BM | 1 |
| da Silva, NV | 1 |
| Martins, PR | 1 |
| Bezerra, FA | 1 |
| Camilo, AL | 1 |
| da Silva, GP | 1 |
| Costa, CC | 1 |
| Ocama, P | 1 |
| Katwere, M | 1 |
| Piloya, T | 1 |
| Feld, J | 1 |
| Opio, KC | 1 |
| Kambugu, A | 1 |
| Katabira, E | 1 |
| Thomas, D | 1 |
| Colebunders, R | 1 |
| Ronald, A | 1 |
| Kriki, P | 1 |
| Thodis, E | 1 |
| Deftereos, S | 1 |
| Panagoutsos, S | 1 |
| Theodoridis, M | 1 |
| Kantartzi, K | 1 |
| Mourvati, E | 1 |
| Prassopoulos, P | 1 |
| Passadakis, P | 1 |
| Vargemezis, V | 1 |
| Kwon, MH | 1 |
| Kong, DH | 1 |
| Jung, SH | 1 |
| Suh, IB | 1 |
| Kim, YM | 1 |
| Ha, KS | 1 |
| BIANCIFIORI, C | 2 |
| BUCCIARELLI, E | 1 |
| CLAYSON, DB | 1 |
| SANTILLI, FE | 1 |
| GRACEY, L | 1 |
| Schwab, CE | 1 |
| Tuschl, H | 1 |
| Kobayashi, K | 1 |
| Yano, S | 1 |
| Ikeda, T | 1 |
| Tokuda, Y | 1 |
| Touge, H | 1 |
| Ishikawa, S | 1 |
| Takeyama, H | 1 |
| Bhadauria, S | 1 |
| Singh, G | 1 |
| Sinha, N | 1 |
| Srivastava, S | 1 |
| Fujii, K | 1 |
| Watanabe, M | 1 |
| Clemmesen, J | 1 |
| Hjalgrim-Jensen, S | 1 |
| Heathcote, J | 1 |
| Wanless, IR | 1 |
| Carroccio, A | 1 |
| Wu, D | 1 |
| Cederbaum, AI | 1 |
| Van Asten, JG | 1 |
| Te Koppele, JM | 1 |
| Horbach, GJ | 1 |
| Nicod, L | 1 |
| Viollon, C | 1 |
| Regnier, A | 1 |
| Jacqueson, A | 1 |
| Richert, L | 1 |
| Mitchell, JR | 1 |
| Potter, WZ | 1 |
| Rosenoer, VM | 1 |
| Tornay, AS | 1 |
| Sherlock, S | 1 |
| Khanina, SB | 1 |
| Dresviannikov, BB | 1 |
| Kiparisov, LN | 1 |
| Linnik, AB | 1 |
| Grasso, P | 1 |
| Crampton, RF | 1 |
| Klastersky, J | 1 |
| Weerts, D | 1 |
| Hensgens, C | 1 |
| Debusscher, L | 1 |
| Szende, B | 1 |
| Juhász, J | 1 |
| Kendrey, G | 1 |
| Severi, L | 1 |
4 reviews available for isoniazid and Liver Neoplasms
| Article | Year |
|---|---|
Hepatotoxicity: newer aspects of pathogenesis and treatment.
Topics: Acetaminophen; Acetylcysteine; Adenoma, Liver Cell; Adult; Amoxicillin; Anabolic Agents; Beverages; | 1995 |
Drug metabolism in the production of liver injury.
Topics: Acetaminophen; Acetanilides; Alkylating Agents; Bromobenzenes; Chemical and Drug Induced Liver Injur | 1975 |
The value of the mouse in carcinogenicity testing.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Epithelium; Ethers, Cycli | 1972 |
More about isonicotinic acid hydrazide toxicity.
Topics: Adenocarcinoma; Adenofibroma; Adenoma; Animals; Carcinoma; Chemical and Drug Induced Liver Injury; C | 1970 |
22 other studies available for isoniazid and Liver Neoplasms
| Article | Year |
|---|---|
Novel 1,2,3-triazole derivatives for use against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain.
Topics: Antitubercular Agents; Carcinoma, Hepatocellular; Cell Proliferation; Click Chemistry; Humans; Isoni | 2011 |
Editorial: new developments in the search for agents to treat tuberculosis.
Topics: Antitubercular Agents; Carcinoma, Hepatocellular; Cell Proliferation; Humans; Isoniazid; Liver Neopl | 2013 |
The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala, Uganda.
Topics: Anti-HIV Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Comorbidity; Female; | 2008 |
A tumor-like manifestation of extrapulmonary tuberculosis in a hemodialysis patient.
Topics: Diabetic Nephropathies; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol; Humans; Ison | 2009 |
Rapid determination of blood coagulation factor XIII activity using protein arrays for serodiagnosis of human plasma.
Topics: Amines; Biomarkers, Tumor; Biotin; Blood Specimen Collection; Carcinoma, Hepatocellular; Factor XIII | 2011 |
INDUCTION OF HEPATOMAS IN CBA-CB-SE MICE BY HYDRAZINE SULPHATE AND THE LACK OF EFFECT OF CROTON OIL ON TUMOUR INDUCTION IN BALB-C-CB-SE MICE.
Topics: Animals; Carcinoma, Hepatocellular; Croton Oil; Hydrazines; Isoniazid; Isonicotinic Acids; Liver; Li | 1964 |
TUBERCULOSIS ABSCESS OF THE LIVER.
Topics: Abscess; Aminosalicylic Acid; Aminosalicylic Acids; Biopsy; Cholecystitis; Diagnosis, Differential; | 1965 |
In vitro studies on the toxicity of isoniazid in different cell lines.
Topics: Animals; Antitubercular Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; DNA Damage; Humans | 2003 |
[Case of liver tuberculosis requiring differentiation from liver metastasis of cancer].
Topics: Aged; Antitubercular Agents; Diagnosis, Differential; Ethambutol; Female; Humans; Isoniazid; Liver N | 2007 |
Isoniazid induces oxidative stress, mitochondrial dysfunction and apoptosis in Hep G2 cells.
Topics: Animals; Antitubercular Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Shape; | 2007 |
Comparative study of tumorigenicity in mice administered transplacentally or neonatally with metabolites of tryptophan and its related compounds.
Topics: 3-Hydroxyanthranilic Acid; Adenoma; Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellula | 1980 |
Epidemiological studies of medically used drugs.
Topics: 2-Naphthylamine; Brain Neoplasms; Epidemiologic Methods; Female; Humans; Isoniazid; Liver Neoplasms; | 1980 |
Ethanol increases content and activity of human cytochrome P4502E1 in a transduced HepG2 cell line.
Topics: Blotting, Western; Carcinoma, Hepatocellular; Cell Line; Cytochrome P-450 CYP2E1; Cytochrome P-450 E | 1994 |
The influence of aging on dimethylnitrosamine-demethylase enzyme kinetics in rat liver microsomes.
Topics: Aging; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Glutathione Transferase; Is | 1995 |
Rifampicin and isoniazid increase acetaminophen and isoniazid cytotoxicity in human HepG2 hepatoma cells.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitubercular Agents; Carcinoma, Hepatocellular; Cell Surv | 1997 |
Drugs and the liver.
Topics: Acetaminophen; Adult; Animals; Chemical and Drug Induced Liver Injury; Chronic Disease; Contraceptiv | 1979 |
Hepatic reactions to drugs.
Topics: Acetaminophen; Adenoma; Adult; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1979 |
[Conservative treatment in carcinoid].
Topics: Adenoma, Basophil; Carcinoid Tumor; Cecum; Colonic Neoplasms; Female; Glucocorticoids; Heart Neoplas | 1970 |
[The possible blastomogenic effect of tubazid and phthivazid in experiments on animals].
Topics: Adenoma; Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Isoniazid; Leukemia, Experimental; | 1972 |
Fever of unexplained origin in patients with cancer.
Topics: Bacterial Infections; Carbenicillin; Cephalothin; Endocarditis; Ethambutol; Female; Fever of Unknown | 1973 |
[Electronmicroscopic studies on INH-induced liver changes and liver tumors in white rats].
Topics: Animals; Cell Membrane; Cell Nucleolus; Cell Nucleus; Endoplasmic Reticulum; Isoniazid; Liver Neopla | 1967 |
Hepatic carcinogenesis in CBA-Cb-Se mice and Cb-Se rats by isonicotinic acid hydrazide and hydrazine sulfate.
Topics: Adenofibroma; Animals; Female; Genetics; Hydrazines; Isoniazid; Liver; Liver Neoplasms; Lung Neoplas | 1968 |