isoniazid has been researched along with Liver Diseases in 90 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Liver Diseases: Pathological processes of the LIVER.
Excerpt | Relevance | Reference |
---|---|---|
"[Purpose] To investigate the frequency and risk factors of severe liver dysfunction in patients receiving isoniazid (INH) mono-therapy for latent tuberculosis infection (LTBI)." | 7.83 | [FREQUENCY AND RISK FACTORS OF SEVERE LIVER DYSFUNCTION IN ISONIAZID MONO-THERAPY FOR LATENT TUBERCULOSIS INFECTION]. ( Ito, K, 2016) |
"The cornerstone of tuberculosis management is a 6-month course of isoniazid, rifampicin, pyrazinamide and ethambutol." | 4.84 | Antituberculosis drug-induced hepatotoxicity: concise up-to-date review. ( Aarnoutse, RE; Boeree, MJ; de Lange, WC; Dekhuijzen, R; Tostmann, A; van der Ven, AJ, 2008) |
"[Purpose] To investigate the frequency and risk factors of severe liver dysfunction in patients receiving isoniazid (INH) mono-therapy for latent tuberculosis infection (LTBI)." | 3.83 | [FREQUENCY AND RISK FACTORS OF SEVERE LIVER DYSFUNCTION IN ISONIAZID MONO-THERAPY FOR LATENT TUBERCULOSIS INFECTION]. ( Ito, K, 2016) |
"Additionally, treating tuberculosis with antibiotics also poses a serious risk of hepatotoxicity in the patient's body." | 3.01 | Deciphering the emerging role of phytocompounds: Implications in the management of drug-resistant tuberculosis and ATDs-induced hepatic damage. ( Ahmad, W; Alharbi, JN; Alomary, MN; Alyahya, SA; Ansari, MA; Ansari, SMA; Ather, H; Hani, U; Imran, MA; Islam, N; Jamous, YF; Shoaib, S; Wahab, S, 2023) |
"Isoniazid LTBI treatment was associated with reduced MTB reactivation in transplant patients with latent MTB risk factors (0." | 2.45 | Tuberculosis in liver transplant recipients: a systematic review and meta-analysis of individual patient data. ( Gould, MK; Holty, JE; Keeffe, EB; Meinke, L; Ruoss, SJ, 2009) |
" Pharmacokinetics of selected anti-infective agents are altered in hepatic disease, necessitating careful monitoring and dosage titration to avoid enhanced drug concentrations and risk of toxicity." | 2.39 | Anti-infective agents and hepatic disease. ( Tschida, SJ; Vance-Bryan, K; Zaske, DE, 1995) |
"Liver diseases are common in patients with HIV due to viral hepatitis B and C co-infections, opportunistic infections or malignancies, antiretroviral drugs and drugs for opportunistic infections." | 1.35 | The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala, Uganda. ( Colebunders, R; Feld, J; Kambugu, A; Katabira, E; Katwere, M; Ocama, P; Opio, KC; Piloya, T; Ronald, A; Thomas, D, 2008) |
"Isoniazid is a widely used drug for the treatment of tuberculosis, but hepatotoxicity is a major concern during treatment." | 1.35 | Protective effects of thiopronin against isoniazid-induced hepatotoxicity in rats. ( Chen, J; Dong, G; He, C; Liu, Y; Peng, R; Yue, J, 2009) |
"Family and personal history of mental illness are also predisposing factors." | 1.31 | [Behavioral disorders after treatment with isoniazid]. ( Djibo, A; Lawan, A, 2001) |
"Acetone pretreatment reduced the inhibition of protein synthesis caused by hydrazine compared to the control." | 1.29 | Role of cytochrome P450 in hydrazine toxicity in isolated hepatocytes in vitro. ( Delaney, J; Timbrell, JA, 1995) |
"During treatment of active pulmonary tuberculosis with isoniazid, rifampicin and ethambutol in 15 patients transaminase activity increased in seven to levels of 60-340 U/l (group I)." | 1.26 | [Plasma levels of rifampicin and isoniazid and serum levels of aminotransferases in combined tuberculostatic treatment (author's transl)]. ( Austerhoff, A; Kindler, U; Knop, P, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 55 (61.11) | 18.7374 |
1990's | 11 (12.22) | 18.2507 |
2000's | 17 (18.89) | 29.6817 |
2010's | 5 (5.56) | 24.3611 |
2020's | 2 (2.22) | 2.80 |
Authors | Studies |
---|---|
Ansari, MA | 1 |
Shoaib, S | 1 |
Alomary, MN | 1 |
Ather, H | 1 |
Ansari, SMA | 1 |
Hani, U | 1 |
Jamous, YF | 1 |
Alyahya, SA | 1 |
Alharbi, JN | 1 |
Imran, MA | 1 |
Wahab, S | 1 |
Ahmad, W | 1 |
Islam, N | 1 |
Mukherjee, TI | 1 |
Hirsch-Moverman, Y | 1 |
Saito, S | 1 |
Gadisa, T | 1 |
Melaku, Z | 1 |
Howard, AA | 1 |
Bourhia, M | 1 |
Ullah, R | 1 |
S Alqahtani, A | 1 |
Ibenmoussa, S | 1 |
Moon, HH | 1 |
Park, SY | 1 |
Kim, JM | 1 |
Park, JB | 1 |
Kwon, CHD | 1 |
Peck, KR | 1 |
Kim, SJ | 1 |
Lee, SK | 1 |
Joh, JW | 1 |
Ito, K | 2 |
Leise, MD | 1 |
Poterucha, JJ | 1 |
Talwalkar, JA | 1 |
Kumar, N | 1 |
Kedarisetty, CK | 1 |
Kumar, S | 1 |
Khillan, V | 1 |
Sarin, SK | 1 |
Adhvaryu, MR | 1 |
Reddy, N | 1 |
Vakharia, BC | 1 |
Young, TH | 1 |
Tang, HS | 1 |
Chao, YC | 1 |
Lee, HS | 1 |
Hsiong, CH | 1 |
Pao, LH | 1 |
Hu, OY | 1 |
Srivastava, RK | 1 |
Sharma, S | 1 |
Verma, S | 1 |
Arora, B | 1 |
Lal, H | 1 |
Ocama, P | 1 |
Katwere, M | 1 |
Piloya, T | 1 |
Feld, J | 1 |
Opio, KC | 1 |
Kambugu, A | 1 |
Katabira, E | 1 |
Thomas, D | 1 |
Colebunders, R | 1 |
Ronald, A | 1 |
Holty, JE | 1 |
Gould, MK | 1 |
Meinke, L | 1 |
Keeffe, EB | 1 |
Ruoss, SJ | 1 |
Yue, J | 1 |
Dong, G | 1 |
He, C | 1 |
Chen, J | 1 |
Liu, Y | 1 |
Peng, R | 1 |
ORLOWSKI, EH | 1 |
EMMRICH, R | 1 |
PETZOLD, H | 1 |
CAMBA, R | 1 |
COSTA, E | 1 |
MURTAS, L | 1 |
HAMKE, H | 1 |
LE CLAIRE, B | 1 |
MCKENNIS, H | 1 |
YARD, AS | 1 |
PAHNELAS, EV | 1 |
NASU, Y | 1 |
DIECKHOFF, J | 1 |
ZIERZ, P | 1 |
PAETZOLD, OH | 1 |
IWAINSKY, H | 1 |
SIEGEL, D | 1 |
GOKCEN, M | 1 |
ZINNEMAN, HH | 1 |
ALIMOV, RSh | 1 |
TANI, P | 1 |
POPPIUS, H | 1 |
REID, JV | 1 |
WRIGHT, R | 1 |
Ubaĭdullaev, AM | 1 |
Belotserkovets, VG | 1 |
Hoshino, H | 1 |
Nakazono, T | 1 |
Masuyama, H | 1 |
Sugita, H | 1 |
Yoshiyama, T | 1 |
Kato, S | 1 |
Jinjuvadia, K | 1 |
Kwan, W | 1 |
Fontana, RJ | 1 |
Xia, YY | 1 |
Zhan, SY | 1 |
Tostmann, A | 1 |
Boeree, MJ | 1 |
Aarnoutse, RE | 1 |
de Lange, WC | 1 |
van der Ven, AJ | 1 |
Dekhuijzen, R | 1 |
Tayal, V | 1 |
Kalra, BS | 1 |
Agarwal, S | 1 |
Khurana, N | 1 |
Gupta, U | 1 |
Panchabhai, TS | 1 |
Ambarkhane, SV | 1 |
Joshi, AS | 1 |
Samant, BD | 1 |
Rege, NN | 1 |
Myles, RK | 1 |
DeSwarte, RD | 1 |
Teruel, JL | 1 |
Marcén, R | 1 |
Celma, ML | 1 |
Bueno, R | 1 |
Jiménez del Cerro, L | 1 |
Matesanz, R | 1 |
Quereda, C | 1 |
Ortuño, J | 1 |
Androsov, EE | 1 |
Vinokurov, VA | 1 |
Garvalinskiĭ, GF | 1 |
Karita, VR | 1 |
Pogrebinskiĭ, MB | 1 |
Holzbach, RT | 1 |
Lesar, TS | 1 |
Zaske, DE | 2 |
Frontera Izquierdo, P | 1 |
Unceta Aguirre, L | 1 |
Tomás Vila, M | 1 |
Calvo Rigual, F | 1 |
Pérez Tamarit, D | 1 |
Maddrey, WC | 1 |
Heathcote, J | 1 |
Wanless, IR | 1 |
Tschida, SJ | 1 |
Vance-Bryan, K | 1 |
Hortoneda Giménez, M | 1 |
Alfonso Sánchez, JL | 1 |
Cortés Vizcaíno, C | 1 |
Sabater Pons, A | 1 |
Robson, SC | 1 |
Pillans, P | 1 |
Willcox, PA | 1 |
French, SW | 1 |
Wong, K | 1 |
Jui, L | 1 |
Albano, E | 1 |
Hagbjork, AL | 1 |
Ingelman-Sundberg, M | 1 |
Ali, J | 1 |
Delaney, J | 1 |
Timbrell, JA | 1 |
Sodhi, CP | 2 |
Rana, SV | 2 |
Mehta, SK | 2 |
Vaiphei, K | 2 |
Attri, S | 1 |
Thakur, S | 1 |
Mehta, S | 2 |
Attari, S | 1 |
Wang, T | 1 |
Shankar, K | 1 |
Ronis, MJ | 1 |
Mehendale, HM | 1 |
Budak-Alpdogan, T | 1 |
Tangün, Y | 1 |
Kalayoglu-Besisik, S | 1 |
Ratip, S | 1 |
Akan, H | 1 |
Baslar, Z | 1 |
Soysal, T | 1 |
Bayik, LA | 1 |
Koç, H | 1 |
Djibo, A | 1 |
Lawan, A | 1 |
Kolpakova, TA | 1 |
Kolpakov, MA | 1 |
Bashkirova, IuV | 1 |
Rachkovskaia, LN | 1 |
Burylin, SIu | 1 |
Liubarskiĭ, MS | 1 |
Ziegler, HK | 1 |
Sinazadeh, M | 1 |
Oldershausen v, HF | 1 |
Byrd, RB | 1 |
Horn, BR | 1 |
Griggs, GA | 1 |
Solomon, DA | 1 |
Spyridis, P | 1 |
Sinaniotis, C | 1 |
Papadea, I | 1 |
Oreopoulos, L | 1 |
Hadjiyiannis, S | 1 |
Papadatos, C | 1 |
Poupon, RY | 1 |
Meyniel, D | 1 |
Petit, J | 1 |
Gustot, P | 1 |
Darnis, F | 1 |
Knop, P | 2 |
Kindler, U | 2 |
Austerhoff, A | 2 |
Rosenberg, SA | 1 |
Seipp, C | 1 |
Sears, HF | 1 |
Thompson, JE | 1 |
Prescott, LF | 1 |
Forrest, JA | 1 |
Adjepon-Yamoah, KK | 1 |
Finlayson, ND | 1 |
Mitchell, JR | 1 |
Snodgrass, WR | 1 |
Gillette, JR | 1 |
O'Brien, RJ | 1 |
Goromaru, T | 1 |
Sokolova, GB | 1 |
Nikolaev, VP | 1 |
Braude, VI | 1 |
Ziia, AV | 1 |
Donald, PR | 1 |
Schoeman, JF | 1 |
O'Kennedy, A | 1 |
Kotal, P | 1 |
Jirsa, M | 1 |
Klepacek, I | 1 |
Martasek, P | 1 |
Kordac, V | 1 |
Pillans, PI | 1 |
Kutt, H | 1 |
Levi, AJ | 1 |
Sherlock, S | 1 |
Walker, D | 1 |
Spellberg, MA | 1 |
Levin, ML | 1 |
Moodie, AS | 1 |
LaMont, JT | 1 |
Litt, IF | 1 |
Schonberg, SK | 1 |
Cohen, MI | 1 |
Sparks, FC | 1 |
Silverstein, MJ | 1 |
Hunt, JS | 1 |
Haskell, CM | 1 |
Pilch, YH | 1 |
Morton, DL | 1 |
Knieriem, HJ | 1 |
Pozzi, E | 1 |
Menghini, P | 1 |
Efrain Salvioli, J | 1 |
Acocella, G | 1 |
Clarke, GB | 1 |
Cuthbert, J | 1 |
Cuthbert, RJ | 1 |
Lees, AW | 1 |
Brummer, DL | 1 |
Verbist, L | 1 |
Rollier, F | 1 |
Tiitinen, H | 1 |
Seki, S | 1 |
Nauwald, G | 1 |
Palleschi, M | 1 |
16 reviews available for isoniazid and Liver Diseases
Article | Year |
---|---|
Deciphering the emerging role of phytocompounds: Implications in the management of drug-resistant tuberculosis and ATDs-induced hepatic damage.
Topics: Antitubercular Agents; Bacterial Proteins; Chemical and Drug Induced Liver Injury; Drug Resistance, | 2023 |
Drug-induced liver injury.
Topics: Adult; Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Causality; Chemical and Drug Induced Li | 2014 |
Antitubercular therapy in patients with cirrhosis: challenges and options.
Topics: Antitubercular Agents; Ethambutol; Humans; Immune System Diseases; Isoniazid; Latent Tuberculosis; L | 2014 |
Tuberculosis in liver transplant recipients: a systematic review and meta-analysis of individual patient data.
Topics: Adult; Antitubercular Agents; Female; Humans; Isoniazid; Liver Diseases; Liver Transplantation; Male | 2009 |
[Systematic review of anti-tuberculosis drug induced adverse reactions in China].
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; China; Drug-Related Side Effects and | 2007 |
Antituberculosis drug-induced hepatotoxicity: concise up-to-date review.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; In | 2008 |
Drug-induced liver disease.
Topics: Analgesics; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Chlorpromazine; Contracep | 1981 |
Antibiotics and hepatic disease.
Topics: Aminoglycosides; Anti-Bacterial Agents; Chloramphenicol; Clindamycin; Humans; Isoniazid; Kinetics; L | 1982 |
Hepatotoxicity: newer aspects of pathogenesis and treatment.
Topics: Acetaminophen; Acetylcysteine; Adenoma, Liver Cell; Adult; Amoxicillin; Anabolic Agents; Beverages; | 1995 |
Anti-infective agents and hepatic disease.
Topics: Anti-Infective Agents; Chloramphenicol; Clindamycin; Fluoroquinolones; Humans; Isoniazid; Liver Dise | 1995 |
[Hepatitis-like liver disorders caused by infections, poisoning and drugs].
Topics: Alcoholism; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cytomegalovirus Infection | 1976 |
Drug metabolism in liver disease.
Topics: Acetaminophen; Acute Disease; Antipyrine; Chemical and Drug Induced Liver Injury; Chronic Disease; H | 1975 |
Biochemical and genetic factors regulating dilantin metabolism in man.
Topics: Aminosalicylic Acids; Animals; Ataxia; Cats; Chlordan; Cycloserine; DDT; Dicumarol; Disulfiram; Enzy | 1971 |
Postoperative juandice.
Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju | 1974 |
[Liver diseases induced by drugs].
Topics: Animals; Arsenicals; Chemical and Drug Induced Liver Injury; Chloroform; Chlorpromazine; Contracepti | 1967 |
More about isonicotinic acid hydrazide toxicity.
Topics: Adenocarcinoma; Adenofibroma; Adenoma; Animals; Carcinoma; Chemical and Drug Induced Liver Injury; C | 1970 |
5 trials available for isoniazid and Liver Diseases
Article | Year |
---|---|
Prevention of hepatotoxicity due to anti tuberculosis treatment: a novel integrative approach.
Topics: Adult; Antitubercular Agents; Blood Sedimentation; Body Weight; Chemical and Drug Induced Liver Inju | 2008 |
[Use of lymphotropic therapy in the multimodality treatment of patients with pulmonary tuberculosis and comorbidity].
Topics: Administration, Oral; Antitubercular Agents; Diabetes Complications; Ethambutol; Humans; Hypoglycemi | 2004 |
Isoniazid chemoprophylaxis. Association with detection and incidence of liver toxicity.
Topics: Adult; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic | 1977 |
Phenylbutazone and isoniazid metabolism in patients with liver disease in relation to previous drug therapy.
Topics: Acetylesterase; Acute Disease; Alcoholism; Alkaline Phosphatase; Aspartate Aminotransferases; Barbit | 1968 |
A metabolic and kinetic study on the association rifampicin-isoniazid.
Topics: Bilirubin; Chronic Disease; Clinical Trials as Topic; Drug Combinations; Drug Interactions; Humans; | 1971 |
69 other studies available for isoniazid and Liver Diseases
Article | Year |
---|---|
Determinants of alcohol use among people living with HIV initiating isoniazid preventive therapy in Ethiopia.
Topics: Adult; Alcohol Drinking; Alcoholism; Antitubercular Agents; Catha; Cross-Sectional Studies; Ethiopia | 2019 |
Evidence of drug-induced hepatotoxicity in the Maghrebian population.
Topics: Adolescent; Adult; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug-Related Side | 2022 |
Isoniazid Prophylaxis for Latent Tuberculosis Infections in Liver Transplant Recipients in a Tuberculosis-Endemic Area.
Topics: Adolescent; Adult; Aged; Antibiotic Prophylaxis; Antitubercular Agents; Child; Child, Preschool; Fem | 2017 |
[FREQUENCY AND RISK FACTORS OF SEVERE LIVER DYSFUNCTION IN ISONIAZID MONO-THERAPY FOR LATENT TUBERCULOSIS INFECTION].
Topics: Adult; Aged; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Humans; Isoniazid; Laten | 2016 |
Quantitative rat liver function test by galactose single point method.
Topics: Alanine Transaminase; Animals; Animals, Laboratory; Aspartate Aminotransferases; Carbon Tetrachlorid | 2008 |
Influence of diabetes on liver injury induced by antitubercular drugs and on silymarin hepatoprotection in rats.
Topics: Animals; Antitubercular Agents; Bilirubin; Chemical and Drug Induced Liver Injury; Diabetes Mellitus | 2008 |
The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala, Uganda.
Topics: Anti-HIV Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Comorbidity; Female; | 2008 |
Protective effects of thiopronin against isoniazid-induced hepatotoxicity in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine Transaminase; Aniline Compounds; Animals; Aspartate Aminotransf | 2009 |
[Investigations on liver damage and disorders of carbohydrate metabolism due to isonicotinic acid hydrazide using the galactose tolerance test].
Topics: Carbohydrate Metabolism; Carbohydrates; Galactose; Isoniazid; Liver; Liver Diseases; Niacin; Nicotin | 1952 |
[Experimental investigations on liver damage by Rimifon (isonicotinic acid hydrazide)].
Topics: Abdominal Injuries; Isoniazid; Liver; Liver Diseases; Niacin; Nicotinic Acids | 1952 |
[Importance of the liver and the kidneys for the convulsant action of isonicotinic acid hydrazide].
Topics: Convulsants; Isoniazid; Kidney; Liver Diseases; Niacin; Nicotinic Acids | 1953 |
[The problem of liver lesions caused by isonicotinic acid hydrazide with special reference to blood proteins].
Topics: Blood Proteins; Gastrointestinal Diseases; Isoniazid; Liver Diseases; Niacin; Nicotinic Acids | 1955 |
The production of fatty livers in rabbits by isoniazid and other hydrazine derivatives.
Topics: Animals; Fatty Liver; Hydrazines; Isoniazid; Liver Diseases; Niacin; Nicotinic Acids; Rabbits | 1956 |
[Investigation of isonicotinic acid hydrazide (INAH) metabolism by azometry. II. INAH metabolism and liver damage].
Topics: Isoniazid; Liver Diseases | 1957 |
[Functional studies on the question of liver damage by isoniazid in children].
Topics: Abdominal Injuries; Child; Humans; Infant; Isoniazid; Liver Diseases | 1957 |
[Liver damage in isoniazid treatment of cutaneous tuberculosis].
Topics: Humans; Isoniazid; Liver Diseases; Tuberculosis; Tuberculosis, Cutaneous | 1958 |
[Metabolism of alpha-ketoacids & the effect of isonicotinic acid hydrazide in experimental liver disorders].
Topics: Biochemical Phenomena; Humans; Isoniazid; Keto Acids; Ketones; Liver Diseases | 1959 |
Liver "autoantibodies" in a case of drug-induced jaundice.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Autoantibodies; Autoimmune Diseases; Drug Hypersensitivit | 1963 |
[EXPERIMENTAL OBSERVATION ON COMPLEX ANTIBACTERIAL THERAPY IN TUBERCULOSIS].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Anti-Bacterial Agents; Guinea Pigs; Insulin; Iso | 1963 |
SIDE EFFECTS OF AN ANTITUBERCULOUS FIVE-DRUG REGIMEN: ETHIONAMIDE, CYCLOSERINE, PYRAZINAMIDE, VIOMYCIN AND ISONIAZID.
Topics: Amyloidosis; Antitubercular Agents; Cycloserine; Deafness; Drug Hypersensitivity; Duodenal Ulcer; Et | 1963 |
CHRONIC SALMONELLOSIS.
Topics: Anemia; Black People; Blood Protein Disorders; Child; Chloramphenicol; Eosinophilia; Fever; Hepatome | 1963 |
[Liver damage in treatment of latent tuberculous infection by isoniazid].
Topics: Adolescent; Adult; Antitubercular Agents; Asian People; Chemical and Drug Induced Liver Injury; Chil | 2006 |
Searching for a needle in a haystack: use of ICD-9-CM codes in drug-induced liver injury.
Topics: Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Chemical and Drug Induced Li | 2007 |
Hepatoprotective effect of tocopherol against isoniazid and rifampicin induced hepatotoxicity in albino rabbits.
Topics: Animals; Antioxidants; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cimetidine; Do | 2007 |
Protective effect of Tinospora cordifolia, Phyllanthus emblica and their combination against antitubercular drugs induced hepatic damage: an experimental study.
Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; I | 2008 |
Isoniazid hepatotoxicity and acetylation during tuberculosis chemoprophylaxis.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; gamma-Glu | 1980 |
Drug allergy--problems and strategies.
Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Respons | 1984 |
[Hepatopathy in kidney transplant patients: incidence, etiology and clinical forms of presentation].
Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Cytomegalovirus Inf | 1984 |
[Isoniazid concentrations in the blood, resected lung tissue and the gallbladder bed in relation to the method of administration to pulmonary tuberculosis patients with stomach and liver diseases].
Topics: Cholecystitis; Gallbladder; Humans; Isoniazid; Liver Diseases; Lung; Pneumonectomy; Stomach Diseases | 1984 |
[Hepatotoxicity of rifampicin and isoniazid in the treatment of tuberculous meningitis (author's transl)].
Topics: Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Hepatomegaly; Humans; Infant; Isoni | 1981 |
Isoniazid-induced liver disease.
Topics: Adult; Age Factors; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Hepatitis, Vira | 1981 |
[Antitubercular chemoprevention: hepatotoxicity and therapeutic compliance].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransf | 1993 |
Treatment of tuberculosis in patients with pre-existing liver disease or following hepatotoxic drug reactions.
Topics: Chemical and Drug Induced Liver Injury; Clinical Protocols; Contraindications; Humans; Isoniazid; Li | 1993 |
Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis.
Topics: Aldehydes; Animals; Blood Proteins; Cytochrome P-450 Enzyme System; Dietary Fats; Dose-Response Rela | 1993 |
Hepatotoxic effects of tuberculosis therapy. A practical approach to a tricky management problem.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Humans; | 1996 |
Role of cytochrome P450 in hydrazine toxicity in isolated hepatocytes in vitro.
Topics: Acetone; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A1; | 1995 |
Study of oxidative stress in isoniazid-induced hepatic injury in young rats with and without protein-energy malnutrition.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytoplasm; Frozen Sections; Glutathione; Glutathion | 1996 |
Study of oxidative-stress in isoniazid-rifampicin induced hepatic injury in young rats.
Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Per | 1997 |
Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1.
Topics: Alanine Transaminase; Allyl Compounds; Animals; Biotransformation; Chemical and Drug Induced Liver I | 2000 |
The frequency of tuberculosis in adult allogeneic stem cell transplant recipients in Turkey.
Topics: Adolescent; Adult; Antitubercular Agents; Female; Graft vs Host Disease; Hematopoietic Stem Cell Tra | 2000 |
[Behavioral disorders after treatment with isoniazid].
Topics: Aging; Alcoholism; Antitubercular Agents; Behavior; Contraindications; Diabetes Mellitus; Female; Hu | 2001 |
[Effects of the enterosorbent SUMS-1 on isoniazid pharmacokinetics and lipid peroxidation in patients with pulmonary tuberculosis and drug-induced hepatic lesions].
Topics: Adult; alpha-Tocopherol; Antitubercular Agents; Ceruloplasmin; Chemical and Drug Induced Liver Injur | 2001 |
[Anticonvulsant drugs and liver damage (Author's transl)].
Topics: Adult; Anticonvulsants; Antitubercular Agents; Autopsy; Chemical and Drug Induced Liver Injury; Chol | 1975 |
Isoniazid liver injury during chemoprophylaxis in children.
Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injur | 1979 |
[Cholestatic hepatitis during treatment with I.N.H. and rifampicin: arguments in favour of the hepatotoxicity of rifampicin (author's transl)].
Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Therapy, Combination; Female; Humans | 1979 |
[Plasma levels of rifampicin and isoniazid and serum levels of aminotransferases in combined tuberculostatic treatment (author's transl)].
Topics: Adult; Aged; Ethambutol; Female; Humans; Isoniazid; Liver Diseases; Male; Prospective Studies; Rifam | 1977 |
Clinical and immunologic studies of disseminated BCG infection.
Topics: Adult; BCG Vaccine; Bone Marrow Diseases; Female; Fever; Granuloma; Humans; Isoniazid; Liver Disease | 1978 |
How safe is isoniazid?
Topics: Adult; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Female; Hepatitis, Viral, Hu | 1978 |
The role of biotransformation in chemical-induced liver injury.
Topics: Acetaminophen; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cr | 1976 |
Hepatoxic reaction to antituberculous drugs: Adjustments to therapeutic regimen.
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Clinical Protocols; Humans; Isoniazid | 1991 |
[Therapeutic drug monitoring of antituberculosis drugs].
Topics: Age Factors; Aminosalicylic Acid; Antitubercular Agents; Biological Availability; Dosage Forms; Drug | 1990 |
[Drug prophylaxis of liver lesions induced by isoniazid and its metabolites].
Topics: Animals; Butylated Hydroxytoluene; Chemical and Drug Induced Liver Injury; Female; Inosine Diphospha | 1989 |
Hepatic toxicity during chemotherapy for severe tuberculosis meningitis.
Topics: Alanine Transaminase; Antitubercular Agents; Aspartate Aminotransferases; Chemical and Drug Induced | 1987 |
Porphyrinostatic effect of isonicotinic acid hydrazide on porphyric chick embryo and yeast.
Topics: 5-Aminolevulinate Synthetase; Animals; Chick Embryo; Isoniazid; Liver; Liver Diseases; Porphyrias; P | 1988 |
Should the dose of antituberculosis drugs be reduced in patients with liver disease?
Topics: Humans; Isoniazid; Liver Diseases; Rifampin; Tuberculosis | 1985 |
Treatment of infectious granulomas of the liver and infectious mononucleosis. Treatment of hepatic schistosomiasis, tuberculosis, syphilis and echinococcus cyst.
Topics: Aminosalicylic Acids; Antimony; Antiprotozoal Agents; Benzenesulfonates; Echinococcosis; Esophageal | 1969 |
Preventive therapy of tuberculous infection.
Topics: Administration, Oral; Adult; Age Factors; Chemical and Drug Induced Liver Injury; Child; Humans; Iso | 1974 |
Isoniazid prophylaxis and deaths in Baltimore, 1972.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Isoniazid; Liver; Liver Disease | 1974 |
Liver disease during adolescence.
Topics: Acute Disease; Adolescent; Chemical and Drug Induced Liver Injury; Chronic Disease; Contraceptives, | 1973 |
Complications of BCG immunotherapy in patients with cancer.
Topics: BCG Vaccine; Fever; Humans; Immunotherapy; Injections; Injections, Intradermal; Isoniazid; Jaundice; | 1973 |
[Liver toxicity of combined rifampicin-isoniazid-ethambutol medication (author's transl)].
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bi | 1974 |
Blood levels of rifampicin in liver diseases.
Topics: Ethambutol; Humans; Isoniazid; Jaundice; Liver; Liver Diseases; Rifampin; Sulfobromophthalein; Tuber | 1974 |
Isoniazid plus rifampicin in the initial treatment of pulmonary tuberculosis.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Drug Combinations; Drug Resistance, Mi | 1972 |
Isoniazid and liver disease.
Topics: Chemical and Drug Induced Liver Injury; Communicable Disease Control; Humans; Isoniazid; Liver Disea | 1971 |
Pharmacological study of rifampicin after repeated high dosage during intermittent combined therapy. II. Bilirubin levels and other biochemical determinations.
Topics: Alanine Transaminase; Analysis of Variance; Aspartate Aminotransferases; Bilirubin; Drug Combination | 1971 |
Isoniazid and ethionamide serum levels and inactivation in Finnish subjects.
Topics: Adolescent; Adult; Age Factors; Alcoholism; Ethionamide; Female; Finland; Humans; Injections, Intrav | 1969 |
[Basic studies on the treatment of liver dysfunction. I. Report by the Basic Study Group, Joint Study Unit on the Economic Therapy, Medical Affairs Bureau, Ministry of Health and Welfare].
Topics: Ammonia; Animals; Humans; Isoniazid; Liver Diseases; Rabbits; Tuberculosis | 1966 |
[Complications in the course of tuberculous spondylitis].
Topics: Cardiovascular Diseases; Central Nervous System Diseases; Female; Gallbladder Diseases; Gastrointest | 1966 |
[Collateral effects of isonicotinic acid hydrazide].
Topics: Blood Coagulation Disorders; Drug Hypersensitivity; Humans; Isoniazid; Liver Diseases; Nervous Syste | 1966 |