isoniazid has been researched along with Leprosy in 123 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A clinical trial was initiated at ALERT, Addis Ababa, Ethiopia, to study the effect of one-year supplementary treatment on the incidence of dapsone-resistant leprosy in lepromatous patients already on dapsone monotherapy." | 9.05 | Relapse rate and incidence of dapsone resistance in lepromatous leprosy patients in Addis Ababa: risk factors and effect of short-term supplementary treatment. ( Mengistu, G; Warndorff van Diepen, T, 1985) |
| "In Paraguay, the National Leprosy/Tuberculosis Program is based on a combined chemotherapy with isoprodian and rifampicin." | 7.67 | Isoprodian and rifampicin in the treatment of leprosy: a descriptive evaluation of therapy durations in 475 Paraguayan leprosy patients. ( Alvarenga, AE; Haubitz, I; Leguizamon, O; Pritze, S, 1989) |
| "Since 1970, when the lifelong monotherapy with dapsone (DDS) in leprosy could be replaced by short-term combination therapy with rifampicin + isoniazid + protionamide + DDS (Isoprodian-RMP), chemotherapeutic research was faced with two problems: (1) to find alternative treatment regimens for cases of intolerance, and (2) to work out forms of therapy allowing a further reduction of the average treatment time of 2 years." | 7.67 | New forms of multidrug therapy for the treatment of leprosy. First report for the practice on rifampicin + sulfamethoxazole-trimethoprim + protionamide and rifampicin + sulfamethoxazole-trimethoprim + isoniazid. ( Freerksen, E; Rosenfeld, M; Spannuth, G, 1989) |
| "Pyrazinamide in a dose of 1500 mg was given to 63 borderline lepromatous (BL) and lepromatous (LL) leprosy patients on different drug regimens for the initial 2 months of therapy." | 5.06 | Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report. ( Katoch, K; Ramanathan, U; Ramu, G, 1988) |
| "A clinical trial was initiated at ALERT, Addis Ababa, Ethiopia, to study the effect of one-year supplementary treatment on the incidence of dapsone-resistant leprosy in lepromatous patients already on dapsone monotherapy." | 5.05 | Relapse rate and incidence of dapsone resistance in lepromatous leprosy patients in Addis Ababa: risk factors and effect of short-term supplementary treatment. ( Mengistu, G; Warndorff van Diepen, T, 1985) |
| " leprae has been reported to be a pseudogene, implicating that isoniazid, which is activated to a potent tuberculocidal agent by catalase, is unlikely to be of therapeutic benefit to leprosy patients." | 3.71 | Identification of catalase-like activity from Mycobacterium leprae and the relationship between catalase and isonicotinic acid hydrazide (INH). ( Chae, GT; Kang, TJ; You, JC, 2001) |
| "In Paraguay, the National Leprosy/Tuberculosis Program is based on a combined chemotherapy with isoprodian and rifampicin." | 3.67 | Isoprodian and rifampicin in the treatment of leprosy: a descriptive evaluation of therapy durations in 475 Paraguayan leprosy patients. ( Alvarenga, AE; Haubitz, I; Leguizamon, O; Pritze, S, 1989) |
| "Since 1970, when the lifelong monotherapy with dapsone (DDS) in leprosy could be replaced by short-term combination therapy with rifampicin + isoniazid + protionamide + DDS (Isoprodian-RMP), chemotherapeutic research was faced with two problems: (1) to find alternative treatment regimens for cases of intolerance, and (2) to work out forms of therapy allowing a further reduction of the average treatment time of 2 years." | 3.67 | New forms of multidrug therapy for the treatment of leprosy. First report for the practice on rifampicin + sulfamethoxazole-trimethoprim + protionamide and rifampicin + sulfamethoxazole-trimethoprim + isoniazid. ( Freerksen, E; Rosenfeld, M; Spannuth, G, 1989) |
| "A comparative study with 2 tier and 3 tier combination of Rifampicin, Clofazimine, DDS, INAH and Thiacetazone was conducted on fifty lepromatous leprosy cases for varying periods." | 3.66 | Multiple drug therapy--a comparative study with 2 tier and 3 tier combination of rifampicin, clofazimine, DDS, INAH and thiacetazone in lepromatous cases. ( Chaudhury, S; Ghosh, S; Hazra, S; Kundu, SK, 1981) |
| "In Africa leprosy is considered endemic." | 1.28 | [Leprosy in Africa. Current status and epidemiological significance]. ( Stingl, P, 1992) |
| " The results revealed that the strain, SR61-L74, was almost completely resistant to DDS, and responded only to the long-term administration of Streptomycin and Isoniazid." | 1.26 | In vitro resistance test of human leprosy bacilli to anti-leprous drugs. ( Fujuda, T; Hagiwara, S; Ishihara, S, 1977) |
| " The common side effect in all cases consisted of red and dark skin pigmentation of varying intensity occuring within 10 weeks of the commencement of therapy." | 1.26 | Side effects of clofazimine therapy. ( Iyer, GG; Ramu, G, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 113 (91.87) | 18.7374 |
| 1990's | 6 (4.88) | 18.2507 |
| 2000's | 2 (1.63) | 29.6817 |
| 2010's | 2 (1.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bera, S | 1 |
| Mondal, D | 1 |
| Jacobson, RR | 1 |
| Gatt, P | 1 |
| Trindade, MÂ | 1 |
| Miyamoto, D | 1 |
| Benard, G | 1 |
| Sakai-Valente, NY | 1 |
| Vasconcelos, Dde M | 1 |
| Naafs, B | 1 |
| LOWE, J | 1 |
| SECRET, E | 2 |
| GOULDING, R | 1 |
| ROBSON, JM | 3 |
| REES, RJ | 4 |
| LEVADITI, C | 1 |
| VAISMAN, A | 1 |
| CHAIGNEAU-ERHARD, H | 1 |
| FERNANDEZ, JM | 1 |
| COMPA, F | 1 |
| MERCAN, AR | 1 |
| GRUNBERG, E | 1 |
| TITSWORTH, EH | 1 |
| COSTELLO, MJ | 2 |
| LATAPI, F | 1 |
| BARBA RUBIO, J | 1 |
| RODRIGUEZ, O | 1 |
| CASTRO ESTRADA, S | 1 |
| BERTACCINI, G | 1 |
| ARGUELLO PITT, L | 1 |
| CONSIGLI, CA | 1 |
| TAYLOR, WH | 1 |
| DIRECTOR, W | 1 |
| LYSIAK, R | 1 |
| CORMIA, FE | 1 |
| BARKER, LP | 1 |
| NELSON, CT | 1 |
| WILSON, EW | 1 |
| CRAMER, JA | 1 |
| PREZIOSI, P | 1 |
| CHAUSSINAND, R | 4 |
| VIETTE, M | 4 |
| KRUG, O | 3 |
| DEZEST, G | 1 |
| GABBAI, A | 1 |
| DORENLOT, H | 1 |
| FLOCH, H | 2 |
| SUREAU, P | 1 |
| DE LIMA, SO | 1 |
| JOPLING, WH | 2 |
| RIDLEY, DS | 2 |
| SIGALL, O | 1 |
| DAVIDSON, WS | 2 |
| MARKIANOS, J | 1 |
| JAIME MELAMED, A | 1 |
| CRUICKSHANK, JC | 1 |
| MUDROW-REICHENOW, L | 1 |
| GUSSENHOVEN, GA | 2 |
| HOBBY, GL | 1 |
| DONIKIAN, MA | 1 |
| FIOL, H | 1 |
| GARRETT, A | 1 |
| SCRAGG, RF | 1 |
| MAGALHAES, MJ | 1 |
| NAGUIB, M | 1 |
| HIRANO, N | 6 |
| SUSHIDA, K | 6 |
| KIMMIG, J | 1 |
| MEYER-ROHN, J | 1 |
| DREISBACH, J | 1 |
| COCHRANE, RG | 1 |
| OCHIAI, Y | 1 |
| MATSUDA, S | 1 |
| HEITE, HJ | 1 |
| RAUSCH, L | 1 |
| EKAMBARAM, V | 1 |
| SHARMA, CS | 1 |
| SHEPARD, CC | 1 |
| CHANG, YT | 1 |
| SMITH, AE | 1 |
| WHEATE, HW | 1 |
| FLOCH, T | 1 |
| KAWAGUCHI, Y | 1 |
| Karat, AB | 1 |
| Rao, PS | 1 |
| Karat, S | 1 |
| Job, CK | 1 |
| Kundu, SK | 1 |
| Ghosh, S | 1 |
| Hazra, S | 1 |
| Chaudhury, S | 1 |
| Ramu, G | 4 |
| Stanley, JN | 2 |
| Pearson, JM | 2 |
| Ellard, GA | 4 |
| Freerksen, E | 8 |
| Styblo, K | 1 |
| Pattyn, SR | 1 |
| Portaels, F | 1 |
| Van Loo, G | 1 |
| Van den Breen, L | 1 |
| Venkatesan, K | 1 |
| Bharadwaj, VP | 1 |
| Desikan, KV | 1 |
| Smith, TC | 1 |
| Richardus, JH | 1 |
| Verduin, PR | 1 |
| van Brakel, WH | 1 |
| Drever, W | 1 |
| Eiglmeier, K | 1 |
| Fsihi, H | 1 |
| Heym, B | 1 |
| Cole, ST | 1 |
| Kang, TJ | 1 |
| You, JC | 1 |
| Chae, GT | 1 |
| Schlaegel, TF | 1 |
| O'Connor, GR | 1 |
| Rosenfeld, M | 5 |
| Ishihara, S | 1 |
| Hagiwara, S | 1 |
| Fujuda, T | 1 |
| Bonnici, E | 2 |
| Depasquale, G | 4 |
| Kriiger-Thiemer, M | 1 |
| Iyer, GG | 1 |
| De Las Aguas, JT | 1 |
| Terencio de las Aguas, J | 1 |
| Innami, S | 1 |
| Leguizamón, OR | 1 |
| Alvarenga, AE | 3 |
| Hamzah, M | 1 |
| Kosasih, A | 1 |
| Krenzien, HN | 1 |
| Rohde, R | 1 |
| Aschhoff, M | 1 |
| Stingl, P | 1 |
| Aoyagi, T | 1 |
| Toyoda, T | 1 |
| Warndorff van Diepen, T | 1 |
| Mengistu, G | 1 |
| Katoch, K | 1 |
| Ramanathan, U | 1 |
| Pritze, S | 1 |
| Leguizamon, O | 1 |
| Haubitz, I | 1 |
| Spannuth, G | 1 |
| Antia, NH | 1 |
| Ambrose, EJ | 1 |
| Upleker, MW | 1 |
| Mahadevan, PR | 1 |
| Mester, L | 1 |
| Grosset, JH | 1 |
| Baohong, J | 1 |
| Ito, T | 1 |
| Leiker, DL | 1 |
| Dietrich, M | 1 |
| Wabitsch, R | 1 |
| Chum, HJ | 1 |
| Parikh, DA | 1 |
| Maniar, JK | 1 |
| Parikh, AC | 1 |
| Ganapati, R | 1 |
| Schirren, C | 1 |
| Piening, E | 1 |
| Wagner, WH | 1 |
| Contreras Duenas, F | 1 |
| Banerjee, DK | 1 |
| Gammon, PT | 2 |
| Waters, MF | 1 |
| Helmy, HS | 1 |
| Leiber, DL | 1 |
| Verhagen, AR | 2 |
| Blenska, W | 1 |
| Kolakowska, E | 1 |
| Agius-Ferrante, A | 1 |
| Paris, C | 1 |
| Grima, W | 1 |
| Urabe, K | 1 |
| Saito, H | 1 |
| Hosokawa, H | 1 |
| Ilardi, I | 1 |
| Mazzacurati, G | 1 |
| Vischer, WA | 1 |
| Yeats, RO | 1 |
| Peters, JH | 1 |
| Levy, L | 1 |
| Lal, HM | 1 |
| Sasaki, N | 1 |
| Schulz, EJ | 1 |
| Egnal, ML | 1 |
| Doevendans, G | 1 |
| Laugier, P | 1 |
| Ellena, V | 1 |
| Barale, T | 1 |
6 reviews available for isoniazid and Leprosy
| Article | Year |
|---|---|
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Leprosy and tuberculosis co-infection: clinical and immunological report of two cases and review of the literature.
Topics: Adult; Brazil; Coinfection; Female; Humans; Immunity, Cellular; Interferon-gamma; Interleukin-12; Is | 2013 |
Leprosy. A preliminary review of the experimental evaluation of drugs for the treatment of leprosy.
Topics: Aminosalicylic Acids; Animals; Anti-Bacterial Agents; Antitubercular Agents; Cycloserine; Ethambutol | 1967 |
[New methods of experimental chemotherapy in leprosy].
Topics: Aminobenzoates; Animals; Culture Techniques; Dapsone; Ethambutol; Isoniazid; Leprosy; Mice; Mycobact | 1969 |
Recent advances in the study of the leprosy bacillus.
Topics: Animals; Cricetinae; Dapsone; Drug Resistance, Microbial; Humans; Isoniazid; Leprosy; Mice; Microbia | 1969 |
[Therapy of leprosy].
Topics: Cycloserine; Humans; Isoniazid; Leprosy; Oils; Plant Extracts; Prognosis; Salicylates; Streptomycin; | 1969 |
10 trials available for isoniazid and Leprosy
| Article | Year |
|---|---|
Treatment of leprosy with rifampicin and isoprodian (L73A).
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Iso | 1975 |
Clinical and bacteriological effects of rifampicin in combination with L73A in leprosy: observation for six months.
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; | 1975 |
Rifampicin and isoprodian in combination in the treatment of leprosy.
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; | 1975 |
Preliminary experience with rifampicin and isoprodian (L73A)--combination in lepromatous leprosy.
Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, | 1975 |
Preliminary experience with rifampicin and isoprodian in combination in leprosy treatment.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Drug Combinations; Dr | 1975 |
Report of combined therapy in leprosy with rifampicin and isoprodian conducted at the Bisidimo-center, Ethiopia.
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Ethiopia; Female; H | 1975 |
Relapse rate and incidence of dapsone resistance in lepromatous leprosy patients in Addis Ababa: risk factors and effect of short-term supplementary treatment.
Topics: Adolescent; Adult; Dapsone; Drug Combinations; Drug Resistance; Humans; Isoniazid; Leprosy; Recurren | 1985 |
Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report.
Topics: Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniaz | 1988 |
Effect of deoxyfructoserotonin (DFS) on lepromatous leprosy.
Topics: Adult; Biopsy; Capsules; Clinical Trials as Topic; Humans; Isoniazid; Leprostatic Agents; Leprosy; M | 1988 |
Comparison of DDS with two combined chemotherapy regimens for multibacillary leprosy. Results after 3 years of treatment. A prospective randomized multicentre study.
Topics: Adult; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotini | 1986 |
107 other studies available for isoniazid and Leprosy
| Article | Year |
|---|---|
Can leprosy be eradicated with chemotherapy? An evaluation of the Malta Leprosy Eradication Project.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprostatic Agents | 2008 |
Isoniazid in leprosy.
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1952 |
[Trial treatment of leprosy with isoniazid].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1952 |
Intracorneal murine leprosy and its response to isoniazid.
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
[Isonicotinic acid hydrazide in the treatment of leprosy].
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1952 |
[Therapeutic activity of isonicotinic acid hydrazide in murine leprosy].
Topics: Actinomycetales Infections; Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
[Treatment of leprosy with isonicotinic acid hydrazide; preliminary communication].
Topics: Communication; Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
Preliminary note on the effect of isoniazid and iproniazid in murine leprosy.
Topics: Actinomycetales Infections; Iproniazid; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
Leprosy (lepromatous type) improved by isoniazid (hydrazid; isonicotinic acid hydrazid).
Topics: Isomerism; Isoniazid; Isonicotinic Acids; Leprosy; Niacin; Nicotinic Acids | 1953 |
Report on 9 months' treatment of leprosy with isoniazid (nydrazid).
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
[First tests of isonicotinic acid hydrazide therapy of leprosy].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
[Treatment of leprosy with isonicotinic acid hydrazide; preliminary communication].
Topics: Communication; Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
The treatment of leprosy with isonicotinyl hydrazine; a case report.
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
Leprosy, lepromatous type: response to isoniazid therapy.
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
Isoniazid (nydrazid) in treatment of cutaneous diseases; Cutaneous tuberculosis, leprosy, sarcoidosis, and miscellaneous dermatoses.
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids; Sarcoidosis; Skin Diseases; Tuberculosis; Tuberculosis, | 1953 |
[Use of isoniazid in leprosy].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
[Treatment of leprosy by isoniazid].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
[Effect of isonicotinic acid hydrazide on the rat infected with Mycobacterium lepraemurium].
Topics: Animals; Isomerism; Isoniazid; Leprosy; Mycobacterium lepraemurium; Niacin; Nicotinic Acids; Rats | 1953 |
[Sixty-two cases of leprosy treated with isoniazid].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1953 |
[Development of infection with Mycobacterium lepraemurium in the rat treated with isonicotinic acid hydrazide].
Topics: Animals; Isomerism; Isoniazid; Leprosy; Mycobacterium lepraemurium; Niacin; Nicotinic Acids; Rats | 1953 |
[Effect of isonicotinic acid hydrazide on Hansen's disease].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids; Sulfones | 1953 |
[Place of isoniazid in leprosy therapy].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids; Sulfones; Thiosemicarbazones | 1953 |
[Treatment of pulmonary tuberculosis with Hansen's disease by streptomycin-isoniazid injections].
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids; Streptomycin; Tuberculosis; Tuberculosis, Pulmonary | 1954 |
Isoniazid in lepromatous leprosy.
Topics: Isoniazid; Leprosy; Leprosy, Lepromatous; Niacin; Nicotinic Acids | 1954 |
[Treatment of lepromatous leprosy with isonicotinic acid hydrazide: advance notice].
Topics: Isomerism; Isoniazid; Leprosy; Leprosy, Lepromatous; Niacin; Nicotinic Acids | 1953 |
Isoniazid alone and in combination with other drugs in the treatment of leprosy.
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1954 |
[Therapeutic effect of isonicotinic acid hydrazide in leprosy].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1954 |
[Leprosy reaction: prophylactic action of isoniazid].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1954 |
Isoniazid in the treatment of rat leprosy.
Topics: Animals; Isoniazid; Leprosy; Niacin; Nicotinic Acids; Rats | 1954 |
[The effects of isoniazid on the pathogen of rat leprosy].
Topics: Animals; Isomerism; Isoniazid; Leprosy; Mycobacterium; Niacin; Nicotinic Acids; Rats | 1954 |
[Isonicotinic acid hydrazide therapy of leprosy].
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1954 |
Isoniazid alone and combined with thiosemicarbazone.
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids; Thiosemicarbazones | 1955 |
Treatment of leprosy patients with isonicotinic acid hydrazide.
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1955 |
Isoniazid with sulphones in lepromatous leprosy.
Topics: Adrenal Cortex; Isoniazid; Leprosy; Leprosy, Lepromatous; Niacin; Nicotinic Acids; Sulfones | 1955 |
The intermittent use of streptomycin and isoniazid singly and together in murine leprosy.
Topics: Actinomycetales Infections; Animals; Humans; Isoniazid; Leprosy; Mice; Niacin; Nicotinic Acids; Stre | 1955 |
[Treatment of leprosy with isonicotinic acid hydrazide].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1955 |
Isoniazid in leprosy treatment.
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1955 |
Isoniazid in leprosy.
Topics: Isoniazid; Leprosy; Niacin; Nicotinic Acids | 1955 |
[The place of isoniazid and the thiosemicarbazones in the treatment of leprosy].
Topics: Isomerism; Isoniazid; Leprosy; Niacin; Nicotinic Acids; Thiosemicarbazones | 1955 |
The activity of diethyldithiolisophthalate alone and combined with isoniazid in the treatment of murine leprosy in the mouse cornea.
Topics: Cornea; Isoniazid; Leprosy; Niacin; Nicotinic Acids; Sulfhydryl Compounds | 1956 |
[Chemotherapy of murine leprosy; the effects of isonicotinoyl-3-methoxy-4-hydroxybenzal hydrazone].
Topics: Actinomycetales Infections; Animals; Humans; Hydrazones; Isoniazid; Leprosy; Mice | 1956 |
[Chemotherapy of murine leprosy; the effects of isonicotinoyl-3-methoxy-4-hydroxybenzal hydrazone].
Topics: Actinomycetales Infections; Animals; Humans; Hydrazones; Isoniazid; Leprosy; Mice | 1956 |
[Chemotherapy of murine leprosy; the effects of isonicotinoyl-3-methoxy-4-hydroxybenzal hydrazone].
Topics: Actinomycetales Infections; Animals; Humans; Hydrazones; Isoniazid; Leprosy; Mice | 1956 |
[Chemotherapy of murine leprosy; the effects of isonicotinoyl-3-methoxy-4-hydroxybenzal hydrazone].
Topics: Actinomycetales Infections; Animals; Humans; Hydrazones; Isoniazid; Leprosy; Mice | 1956 |
[New observations on the effect of isonicotinic acid hydrazide in murine infection caused by Stefansky bacillus].
Topics: Animals; Bacillus; Insecta; Isoniazid; Leprosy; Mice | 1955 |
Chemotherapy of murine leprosy. II. The effects of isonicotinoyl-3. 4-dimethoxybenzal hydrazone.
Topics: Actinomycetales Infections; Animals; Humans; Hydrazones; Isoniazid; Leprosy; Mice | 1957 |
[Chemotherapy of Stefansky leprosy with N-acetyl-D-glucosaminyl-isoniazid & [beta-methyl-mercaptopropionaldehyde]isonicotinic acid hydrazone].
Topics: Aldehydes; Glucosamine; Hydrazones; Isoniazid; Isonicotinic Acids; Leprosy | 1957 |
Chemotherapy of murine leprosy. 3. The effects of isonicotinoyl-3-methoxy-4-ethoxybenzal hydrazone and isoniciotinoyl-3.4-diethoxybenzal hydrazone.
Topics: Animals; Humans; Hydrazones; Isoniazid; Leprosy; Mice | 1958 |
A study of the effect of streptohydrazid on lepromatous leprosy over a period of about three years.
Topics: Isoniazid; Leprosy; Leprosy, Lepromatous; Streptomycin | 1958 |
Paper electrophoretic analysis of sera from leprous mice treated with INH and its derivatives.
Topics: Animals; Blood Proteins; Electrophoresis, Paper; Isoniazid; Leprosy; Mice; Oxidation-Reduction | 1959 |
Chemotherapy of murine leprosy. 4. The effects of isonicotinoyl-3, 4-diethoxybenzal hydrazone on murine leprosy.
Topics: Actinomycetales Infections; Animals; Humans; Hydrazones; Isoniazid; Leprosy; Mice | 1959 |
[On the influence of INH-treatment of rat leprosy on the number of leproma in respect to lowmolecular weight SH-compounds].
Topics: Animals; Isoniazid; Leprosy; Rats | 1960 |
Treatment of reactions in leprosy by aqueous sulphetrone injections and oral INH in a rural centre.
Topics: Isoniazid; Leprosy; Rural Population; Sulfones | 1961 |
Effect of several anti-leprosy drugs on multiplication of human leprosy bacilli in footpads of mice.
Topics: Aminosalicylic Acid; Animals; Cycloserine; Isoniazid; Leprosy; Mice; Mycobacterium leprae; Sulfones | 1962 |
METABOLIC PATHWAY AND ITS RELATIONSHIP TO THE BIOLOGICAL ACTIVITY OF SOME TUBERCULOSTATIC AND LEPROSTATIC AGENTS.
Topics: Antitubercular Agents; Azoles; Drug Resistance; Drug Resistance, Microbial; Humans; Isoniazid; Lepro | 1964 |
TWO UNUSUAL CASES OF NERVE ABSCESS.
Topics: Abscess; Humans; Isoniazid; Leprosy; Nerve Tissue; Peripheral Nervous System Diseases; Prednisolone; | 1964 |
[THE CHEMOTHERAPY OF LEPROSY].
Topics: Cycloserine; Dapsone; Drug Therapy; Humans; Isoniazid; Leprosy; Sulfamethoxypyridazine; Sulfones; Th | 1964 |
[Relation between host resistance and disease type in leprosy. 7. Effects of chemotherapy in primary infection on leproma development in superinfection in benign murine leprosy].
Topics: Actinomycetales Infections; Animals; Communicable Diseases; Humans; Isoniazid; Leprosy; Mice; Superi | 1962 |
Streptomycin and INAH in the treatment of leprosy. A preliminary communication.
Topics: Female; Humans; Isoniazid; Leprosy; Male; Streptomycin | 1967 |
Multiple drug therapy--a comparative study with 2 tier and 3 tier combination of rifampicin, clofazimine, DDS, INAH and thiacetazone in lepromatous cases.
Topics: Adolescent; Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid | 1981 |
Evaluation of drug regimen in lepromatous leprosy--II.
Topics: Adult; Animals; Clofazimine; Dapsone; Drug Administration Schedule; Drug Resistance, Microbial; Huma | 1983 |
An investigation of dapsone compliance using an isoniazid-marked formulation.
Topics: Adolescent; Adult; Aged; Capsules; Creatinine; Dapsone; Drug Combinations; Female; Humans; Isoniazid | 1983 |
Treatment of leprosy using combination therapy--but how?
Topics: Humans; Isoniazid; Leprostatic Agents; Leprosy; Prothionamide | 1983 |
Tuberculosis and its control: lessons to be learned from past experience, and implications for leprosy control programmes.
Topics: Adolescent; Adult; BCG Vaccine; Child; Child, Preschool; Developing Countries; Drug Resistance, Micr | 1983 |
Activity of the combination of isoniazid, protionamide and dapsone against Mycobacterium leprae and some other mycobacteria.
Topics: Animals; Dapsone; Drug Interactions; Drug Therapy, Combination; Isoniazid; Isonicotinic Acids; Lepro | 1981 |
Study on drug interactions.
Topics: Adult; Clofazimine; Dapsone; Drug Interactions; Drug Therapy, Combination; Humans; Isoniazid; Lepros | 1980 |
Relapse rates in patients treated with dapsone monotherapy and combinations of dapsone and thiambutosine, thiacetazone, isoniazid and streptomycin in the pre-MDT era.
Topics: Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprostatic Agents; Leprosy; Male; Ph | 1994 |
Isoniazid and hepatotoxicity.
Topics: Female; Humans; Isoniazid; Leprosy; Liver; Pregnancy | 1993 |
Side-effects of Isoprodian compared with WHO-MDT in rural Nepal.
Topics: Adolescent; Adult; Aged; Child; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Human | 1993 |
On the catalase-peroxidase gene, katG, of Mycobacterium leprae and the implications for treatment of leprosy with isoniazid.
Topics: Antitubercular Agents; Bacterial Proteins; Cloning, Molecular; Cosmids; Genes, Bacterial; Isoniazid; | 1997 |
Identification of catalase-like activity from Mycobacterium leprae and the relationship between catalase and isonicotinic acid hydrazide (INH).
Topics: Ammonium Sulfate; Animals; Antitubercular Agents; Bacterial Proteins; Base Sequence; Benzidines; Cat | 2001 |
Controlling the spread of leprosy--some observations on.
Topics: Allied Health Personnel; Antitubercular Agents; Dapsone; Drug Resistance, Microbial; Drug Therapy, C | 1976 |
Metastatic nonsuppurative uveitis.
Topics: Choroiditis; Endophthalmitis; Humans; Isoniazid; Leprosy; Pigment Epithelium of Eye; Syphilis; Syphi | 1977 |
Leprosy eradication project of Malta. First published report after 5 years running.
Topics: Adolescent; Adult; Aged; Bacteriological Techniques; Child; Dapsone; Drug Therapy, Combination; Fema | 1977 |
In vitro resistance test of human leprosy bacilli to anti-leprous drugs.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Isoniazid; Leprostatic Agents; Leprosy; Microbial Sensi | 1977 |
[Research in the campaign against leprosy (author's transl)].
Topics: Animals; Armadillos; Dapsone; Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Mice; Models, B | 1977 |
Combined therapy in leprosy. Background and findings.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic Agents; Lepros | 1978 |
Side effects of clofazimine therapy.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Female; Humans; Ichthyosis; Isoniazid; Leprosy; Male; Skin | 1976 |
[New drugs in the treatment of leprosy].
Topics: Dapsone; Drug Combinations; Drug Evaluation; Humans; Isoniazid; Isonicotinic Acids; Leprosy; Prothio | 1976 |
Preliminary experience with combined therapy using rifampicin and isoprodian (L73A).
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Lepros | 1975 |
Treatment of leprosy with rifampicin and isoprodian in 38 patients at St. Thomas Hospital, Chetput, Sout India.
Topics: Adolescent; Adult; Child; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Ind | 1975 |
[Leprosy in Africa. Current status and epidemiological significance].
Topics: Adolescent; Adult; Africa; Child; Cross-Sectional Studies; Drug Therapy, Combination; Humans; Isonia | 1992 |
[Drugs used in tuberculosis and leprosy].
Topics: Administration, Oral; Antibiotics, Antitubercular; Clofazimine; Dapsone; Humans; Injections, Intramu | 1990 |
Ethionamide, prothionamide and thiacetazone self-administration. Studies of patient compliance using isoniazid-marked formulations.
Topics: Adolescent; Adult; Aged; Dapsone; Drug Therapy, Combination; Ethionamide; Female; Humans; Isoniazid; | 1986 |
Isoprodian and rifampicin in the treatment of leprosy: a descriptive evaluation of therapy durations in 475 Paraguayan leprosy patients.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Lepros | 1989 |
New forms of multidrug therapy for the treatment of leprosy. First report for the practice on rifampicin + sulfamethoxazole-trimethoprim + protionamide and rifampicin + sulfamethoxazole-trimethoprim + isoniazid.
Topics: Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Leprosy; Prothionamide; Sulfametho | 1989 |
The first joint THELEP-Sasakawa Memorial Health Foundation workshop on experimental chemotherapy of leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Isoniazid; Leprosy; Mycobacterium leprae; Mycobacterium | 1987 |
The Malta experience. Isoprodian-rifampicin combination treatment for leprosy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Dapsone; Drug Combinations; Drug Therapy, Combina | 1986 |
First assessment of the Malta Leprosy Eradication Project.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Evaluation Studies as Topic; Follow-Up Studie | 1986 |
Report of the joint leprosy-tuberculosis project in Paraguay.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic Agents; Lepros | 1986 |
The impact of MDT implementation in the Tanzania National TB-Leprosy Programme.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotinic Acids | 1986 |
Recent trends in chemotherapy of leprosy.
Topics: Clofazimine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic A | 1985 |
[Chemotherapy of leprosy].
Topics: Dapsone; Female; Humans; Isoniazid; Leprosy; Male; Sulfadiazine; Sulfones; Thioacetazone; Urea; Vita | 1970 |
[Early diagnosis, therapy, and research in the control of leprosy].
Topics: Aniline Compounds; Drug Synergism; Europe; Humans; Hyperbaric Oxygenation; Isoniazid; Leprosy; Phena | 1970 |
Some observations on the pharmacology of clofazimine (B663).
Topics: Aniline Compounds; Animals; Clofazimine; Dose-Response Relationship, Drug; Feces; Humans; Isoniazid; | 1974 |
Dapsone acetylation and the treatment of leprosy.
Topics: Acetates; Dapsone; Humans; Isoniazid; Leprosy | 1972 |
Assessment of the bacteriological effect of combined treatment with rifadin, sulfamethoxypyrazine, and isoniazide in lepromatous leprosy.
Topics: Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Microbial Sensitivity Tests; Muscle, Smooth; | 1973 |
Fundamental data, methods and goals of present research on the treatment of leprosy.
Topics: Animals; Animals, Laboratory; Antitubercular Agents; Clofazimine; Dapsone; Ethionamide; Humans; In V | 1973 |
A new analogous model for the detection and evaluation of chemotherapeutic products effective in leprosy.
Topics: Aniline Compounds; Animals; Dapsone; Disease Models, Animal; Drug Combinations; Ethionamide; Humans; | 1972 |
A pilot study of leprosy treatment with a combination of various antileprosy drugs. Preliminary report.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Male; Pilot Pro | 1973 |
[Administration of a new antimycobacterial combined therapy in leprosy in East Africa].
Topics: Africa, Eastern; Antitubercular Agents; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazi | 1973 |
The leprosy eradication-project of Malta.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Ethionamide; Female; Humans; Infant; Infant, Newbo | 1973 |
A photochromogenic acid-fast bacillus isolated from mouse-leproma.
Topics: Acid Phosphatase; Amides; Amidohydrolases; Aminosalicylic Acids; Animals; Catalase; Ethambutol; Guin | 1968 |
Antimicrobial activity of the leprostatic drug 3-(p-chloranilino)-10-(p-chlorphenyl-2,10-dihydro-2-(isopropylimino)-phenazine (G 30'320, B. 663).
Topics: Animals; Antitubercular Agents; Aspergillosis; Candidiasis; Chloroquine; Cricetinae; Disease Models, | 1970 |
Preliminary test using DMSO as a vehicle for drugs in leprosy.
Topics: Aminosalicylic Acids; Dapsone; Dimethyl Sulfoxide; Humans; Isoniazid; Leprosy; Pharmaceutical Vehicl | 1967 |
Dapsone acetylation in man: another example of polymorphic acetylation.
Topics: Acetates; Acylation; Adult; Blood Proteins; Dapsone; Female; Fluorometry; Genetics, Medical; Half-Li | 1971 |
Transmission of human leprosy to experimental animals: studies with "Chatterjee" bacilli.
Topics: Animals; Antitubercular Agents; Cornea; Cortisone; Ethambutol; Isoniazid; Leprosy; Liver; Mice; Myco | 1965 |
A histopathological study on the effect of various drugs in experimental murine leprosy. II. On a salivary gland hormone (Parotin) and an unsaturated fatty acid (RTB).
Topics: Animals; Bacteriolysis; Fatty Acids; Granuloma; Histiocytes; Hormones; Isoniazid; Leprosy; Mice; Pha | 1969 |
Treatment of leprosy with a combination of injectable thiambutosine (CIBA 1906), streptomycin and isoniazid.
Topics: Africa, Southern; Humans; Isoniazid; Leprosy; Streptomycin; Thiourea | 1966 |
[Rapid action of isoniazid in a case of reactional leprosy].
Topics: Humans; Isoniazid; Leprosy; Male | 1966 |