Page last updated: 2024-10-29

isoniazid and Innate Inflammatory Response

isoniazid has been researched along with Innate Inflammatory Response in 21 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Research Excerpts

ExcerptRelevanceReference
" The acetylhydrazine metabolite was found to be much less cytotoxic than hydrazine in this hepatocyte inflammation model."7.74Role of hydrazine in isoniazid-induced hepatotoxicity in a hepatocyte inflammation model. ( Mashregi, M; O'Brien, PJ; Tafazoli, S, 2008)
"Ferroptosis and inflammation induced by cerebral hemorrhage result in an excessive inflammatory response and irreversible neuronal injury."5.62Pyridoxal Isonicotinoyl Hydrazone Improves Neurological Recovery by Attenuating Ferroptosis and Inflammation in Cerebral Hemorrhagic Mice. ( Chen, J; Lin, X; Lin, Z; Ru, J; Wen, M; Yang, S; Yao, C; Zhang, H; Zhuge, Q, 2021)
" The acetylhydrazine metabolite was found to be much less cytotoxic than hydrazine in this hepatocyte inflammation model."3.74Role of hydrazine in isoniazid-induced hepatotoxicity in a hepatocyte inflammation model. ( Mashregi, M; O'Brien, PJ; Tafazoli, S, 2008)
"Ferroptosis and inflammation induced by cerebral hemorrhage result in an excessive inflammatory response and irreversible neuronal injury."1.62Pyridoxal Isonicotinoyl Hydrazone Improves Neurological Recovery by Attenuating Ferroptosis and Inflammation in Cerebral Hemorrhagic Mice. ( Chen, J; Lin, X; Lin, Z; Ru, J; Wen, M; Yang, S; Yao, C; Zhang, H; Zhuge, Q, 2021)
"Seventy-five male patients with pulmonary tuberculosis (mean age, 40."1.40Association of serum levels of iron, copper, and zinc, and inflammatory markers with bacteriological sputum conversion during tuberculosis treatment. ( de Melo Guedes de Oliveira, HM; de Oliveira, MM; Delogo, KN; Dos Anjos, MJ; Kritski, AL; Mesquita, ED; Miranda, PF; Moraes, ML; Netto, AR; Ramalho, DM, 2014)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19909 (42.86)18.7374
1990's0 (0.00)18.2507
2000's2 (9.52)29.6817
2010's6 (28.57)24.3611
2020's4 (19.05)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Zhang, H1
Wen, M1
Chen, J1
Yao, C1
Lin, X1
Lin, Z1
Ru, J1
Zhuge, Q1
Yang, S1
Song, Y1
Qu, X1
Tao, L1
Gao, H1
Zhang, Y1
Zhai, J1
Gong, J1
Hu, T1
Kumawat, M1
Madhyastha, H1
Singh, M1
Revaprasadu, N1
Srinivas, SP1
Daima, HK1
Zhu, W1
Su, H1
Wei, Y1
Huang, Y1
Chen, S1
Shi, Y1
Long, Y1
Qiu, Y1
Wei, J1
Huang, SF1
Chen, MH1
Wang, FD1
Tsai, CY1
Fung, CP1
Su, WJ1
Sumenkova, DV1
Russkikh, GS1
Poteryaeva, ON1
Polyakov, LM1
Panin, LE1
Gourishankar, A1
Navarro, F1
Debroy, AN1
Smith, KC1
Moraes, ML1
Ramalho, DM1
Delogo, KN1
Miranda, PF1
Mesquita, ED1
de Melo Guedes de Oliveira, HM1
Netto, AR1
Dos Anjos, MJ1
Kritski, AL1
de Oliveira, MM1
Hassan, HM1
Guo, H1
Yousef, BA1
Guerram, M1
Hamdi, AM1
Zhang, L1
Jiang, Z1
LAI, G1
DOMENJOZ, R1
SPAIN, DM1
KALLIOMAKI, JL1
KEYRILAINEN, TO1
MARKKANEN, TK1
Shkurupii, VA1
Kozyaev, MA1
Nadeev, AP1
Tafazoli, S1
Mashregi, M1
O'Brien, PJ1
Parker, MD1
Irwin, RS1
Bandmann, HJ1
Ryan, SJ1
Frank, RN1
Green, WR1
Spicková, V1
Hlavinka, F1
Furnas, DW1

Other Studies

21 other studies available for isoniazid and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Pyridoxal Isonicotinoyl Hydrazone Improves Neurological Recovery by Attenuating Ferroptosis and Inflammation in Cerebral Hemorrhagic Mice.
    BioMed research international, 2021, Volume: 2021

    Topics: Animals; Apoptosis; Cell Death; Cerebral Hemorrhage; Ferric Compounds; Ferroptosis; Inflammation; Ir

2021
Exploration of the underlying mechanisms of isoniazid/rifampicin-induced liver injury in mice using an integrated proteomics and metabolomics approach.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:12

    Topics: Animals; Chemical and Drug Induced Liver Injury; Fatty Liver; Inflammation; Isoniazid; Liver; Male;

2022
Double functionalized haemocompatible silver nanoparticles control cell inflammatory homeostasis.
    PloS one, 2022, Volume: 17, Issue:10

    Topics: Curcumin; Cytokines; Homeostasis; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Isoniazid;

2022
Asiatic acid ameliorates rifampicin- and isoniazid-induced liver injury in vivo by regulating sphingolipid metabolism and mitogen-activated protein kinase signalling pathways.
    Basic & clinical pharmacology & toxicology, 2023, Volume: 133, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; In

2023
Efficacy of isoniazid salvage therapy for latent tuberculosis infection in patients with immune-mediated inflammatory disorders - A retrospective cohort study in Taiwan.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:6

    Topics: Adult; Aged; Antitubercular Agents; Female; Humans; Immunocompromised Host; Incidence; Inflammation;

2018
Activity of matrix metalloproteinases during antimycobacterial therapy in mice with simulated tuberculous inflammation.
    Bulletin of experimental biology and medicine, 2013, Volume: 155, Issue:1

    Topics: Animals; Antitubercular Agents; Inflammation; Isoniazid; Male; Matrix Metalloproteinase 2; Matrix Me

2013
Isoniazid hepatotoxicity with clinical and histopathology correlate.
    Annals of clinical and laboratory science, 2014,Winter, Volume: 44, Issue:1

    Topics: Adolescent; Biopsy; Female; Fibrosis; Humans; Inflammation; Isoniazid; Liver; Lymphocytes

2014
Association of serum levels of iron, copper, and zinc, and inflammatory markers with bacteriological sputum conversion during tuberculosis treatment.
    Biological trace element research, 2014, Volume: 160, Issue:2

    Topics: Adult; Antitubercular Agents; Biomarkers; C-Reactive Protein; Copper; Ethambutol; Hemoglobins; Host-

2014
Role of Inflammatory and Oxidative Stress, Cytochrome P450 2E1, and Bile Acid Disturbance in Rat Liver Injury Induced by Isoniazid and Lipopolysaccharide Cotreatment.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9

    Topics: Animals; Antitubercular Agents; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cytoch

2016
[Case of polyserositis treated with isonicotinic acid hydrazide].
    Rassegna medica, 1952, Volume: 29, Issue:5

    Topics: Chronic Disease; Inflammation; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Serositis

1952
[Effects of isonicotinic acid hydrazide on the formalin inflammation and the dextran edema].
    Schweizerische medizinische Wochenschrift, 1952, Oct-04, Volume: 82, Issue:40

    Topics: Dextrans; Edema; Formaldehyde; Inflammation; Isoniazid; Niacin; Nicotinic Acids; Respiratory Hyperse

1952
Effect of isoniazid on early acute inflammatory response in mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1953, Volume: 82, Issue:2

    Topics: Animals; Inflammation; Isoniazid; Mice; Niacin; Nicotinic Acids

1953
The anti-inflammatory synergism of prednisone and isonicotinic acid hydrazide.
    Annales medicinae experimentalis et biologiae Fenniae, 1958, Volume: 36, Issue:1

    Topics: Anti-Inflammatory Agents; Drug Interactions; Humans; Inflammation; Isoniazid; Prednisone

1958
Ultrastructural characteristics of type A epithelioid cells during BCG-granulomatosis and treatment with lysosomotropic isoniazid.
    Bulletin of experimental biology and medicine, 2006, Volume: 141, Issue:4

    Topics: Aldehydes; Animals; Antitubercular Agents; Dextrans; Epithelial Cells; Granuloma; Inflammation; Ison

2006
Role of hydrazine in isoniazid-induced hepatotoxicity in a hepatocyte inflammation model.
    Toxicology and applied pharmacology, 2008, May-15, Volume: 229, Issue:1

    Topics: Animals; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Hepatocytes; Hydrazines; Hyd

2008
Mycobacterium kansasii tendinitis and fasciitis. Report of a case treated successfully with drug therapy alone.
    The Journal of bone and joint surgery. American volume, 1975, Volume: 57, Issue:4

    Topics: Ethambutol; Fascia; Humans; Inflammation; Isoniazid; Male; Middle Aged; Mycobacterium Infections; Ri

1975
[Histology of drug exanthema (histopathology of hematogenic contact eczema)].
    Archiv fur klinische und experimentelle Dermatologie, 1970, Volume: 237, Issue:1

    Topics: Adult; Dermatitis, Contact; Drug Eruptions; Eczema; Exanthema; Female; Humans; Inflammation; Isoniaz

1970
Bilateral inflammatory pseudotumors of the ciliary body.
    American journal of ophthalmology, 1971, Volume: 72, Issue:3

    Topics: Administration, Topical; Anti-Inflammatory Agents; Atropine; Biopsy; Ciliary Body; Diagnosis, Differ

1971
[Nonspecific inflammation of the intervertebral disk in 2 children].
    Ceskoslovenska pediatrie, 1968, Volume: 23, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Inflammation; Intervertebral Disc; Ison

1968
Recognition of scleroma (rhinoscleroma).
    The Laryngoscope, 1968, Volume: 78, Issue:11

    Topics: Adult; Aminosalicylic Acids; Humans; Inflammation; Isoniazid; Klebsiella; Male; Middle Aged; Rhinosc

1968