isoniazid has been researched along with Extensively Drug-Resistant Tuberculosis in 83 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Extensively Drug-Resistant Tuberculosis: Tuberculosis resistant to ISONIAZID and RIFAMPIN and at least three of the six main classes of second-line drugs (AMINOGLYCOSIDES; polypeptide agents; FLUOROQUINOLONES; THIOAMIDES; CYCLOSERINE; and PARA-AMINOSALICYLIC ACID) as defined by the CDC.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Resectional lung surgery combined with isoniazid- and rifampin-based anti-tuberculous chemotherapy can be an effective treatment strategy for patients with well-localized, cavitary pulmonary MDR-TB and XDR-TB." | 5.35 | Pulmonary resection combined with isoniazid- and rifampin-based drug therapy for patients with multidrug-resistant and extensively drug-resistant tuberculosis. ( Cho, JS; Kang, H; Kim, JH; Park, SK; Smego, RA, 2009) |
| "After the introduction of isoniazid and rifampicin, the second one discovered in the Lepetit Research Laboratories (Milan, Italy), under the supervision of Professor Piero Sensi, tuberculosis (TB) was considered an illness of the past." | 4.90 | Trends in discovery of new drugs for tuberculosis therapy. ( Pasca, MR; Riccardi, G, 2014) |
| " The respective sensitivity and specificity were 84% and 100% for isoniazid (INH); 82% and 100% for rifampin (RIF); 67% and 100% for amikacin (AK); and both 100% for ofloxacin (OFX)." | 3.88 | Evaluation of Nitrate Reductase Assay for Early Detection of Multi and Extensively Drug Resistance Tuberculosis in our Setup. ( Ahmed, P; Gardezi, AH; Ikram, AI; Lalani, FK; Satti, ML; Zaman, G, 2018) |
| " Minimal inhibitory concentrations (MICs) of isoniazid (INH), rifampicin (RMP) and levofloxacin (LVX) from 169 DR tuberculosis (TB) isolates, 78 of them monoresistant to INH, 13 to RMP, 7 to LVX, and 71 MDR-TB, were determined." | 3.79 | Molecular and phenotypic characterisation of Mycobacterium tuberculosis resistant to anti-tuberculosis drugs. ( Cataldi, AA; Di Giulio, AB; Imperiale, BR; Morcillo, NS; Zumárraga, MJ, 2013) |
| "Currently, no information is available on the effect of resistance/susceptibility to first-line drugs different from isoniazid and rifampicin in determining the outcome of extensively drug-resistant tuberculosis (XDR-TB) patients, and whether being XDR-TB is a more accurate indicator of poor clinical outcome than being resistant to all first-line anti-tuberculosis (TB) drugs." | 3.74 | Clinical and operational value of the extensively drug-resistant tuberculosis definition. ( Besozzi, G; Cirillo, DM; Codecasa, LR; Ferrara, G; Girardi, E; Gori, A; Kliiman, K; Lange, C; Matteelli, A; Migliori, GB; Raviglione, MC; Spanevello, A; Toungoussova, OS, 2007) |
| "All ciprofloxacin DST results were susceptible by both methods." | 1.56 | MDR/XDR-TB Colour Test for drug susceptibility testing of Mycobacterium tuberculosis, Northwest Ethiopia. ( Balada-Llasat, JM; Evans, CA; Gelaw, B; Kelley, HV; Shibabaw, A; Tesfaye, E; Tessema, B; Torrelles, JB; Wang, SH, 2020) |
| "tuberculosis were obtained from the Novosibirsk Research Institute of Tuberculosis, Russia." | 1.40 | Characterization of extensively drug-resistant Mycobacterium tuberculosis isolates circulating in Siberia. ( Alkhovik, OI; Cherednichenko, AG; Dymova, MA; Filipenko, ML; Khrapov, EA; Petrenko, TI, 2014) |
| "Isoniazid (INH) is a central component of drug regimens used worldwide to treat tuberculosis." | 1.37 | Prevalence of mutations at codon 463 of katG gene in MDR and XDR clinical isolates of Mycobacterium tuberculosis in Belarus and application of the method in rapid diagnosis. ( Arjomandzadegan, M; Farazi, AA; Ghaznavi-Rad, E; Owlia, P; Ranjbar, R; Sadrnia, M; Sofian, M; Surkova, LK; Titov, LP, 2011) |
| "Resectional lung surgery combined with isoniazid- and rifampin-based anti-tuberculous chemotherapy can be an effective treatment strategy for patients with well-localized, cavitary pulmonary MDR-TB and XDR-TB." | 1.35 | Pulmonary resection combined with isoniazid- and rifampin-based drug therapy for patients with multidrug-resistant and extensively drug-resistant tuberculosis. ( Cho, JS; Kang, H; Kim, JH; Park, SK; Smego, RA, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (7.23) | 29.6817 |
| 2010's | 62 (74.70) | 24.3611 |
| 2020's | 15 (18.07) | 2.80 |
| Authors | Studies |
|---|---|
| Khanna, A | 2 |
| Raj, VS | 1 |
| Tarai, B | 1 |
| Sood, R | 1 |
| Pareek, PK | 1 |
| Upadhyay, DJ | 1 |
| Sharma, P | 1 |
| Rattan, A | 1 |
| Saini, KS | 1 |
| Singh, H | 1 |
| Krátký, M | 1 |
| Vinšová, J | 1 |
| Buchta, V | 1 |
| Horvati, K | 1 |
| Bösze, S | 1 |
| Stolaříková, J | 1 |
| Bakal, RL | 1 |
| Gattani, SG | 1 |
| Li, D | 1 |
| Gao, N | 1 |
| Zhu, N | 1 |
| Lin, Y | 1 |
| Li, Y | 3 |
| Chen, M | 1 |
| You, X | 1 |
| Lu, Y | 1 |
| Wan, K | 1 |
| Jiang, JD | 1 |
| Jiang, W | 1 |
| Si, S | 1 |
| Dixit, PP | 2 |
| Thore, SN | 1 |
| Micheni, LN | 1 |
| Kassaza, K | 1 |
| Kinyi, H | 1 |
| Ntulume, I | 1 |
| Bazira, J | 1 |
| Liu, Y | 2 |
| Posey, DL | 1 |
| Yang, Q | 1 |
| Weinberg, MS | 1 |
| Maloney, SA | 1 |
| Lambert, LA | 1 |
| Ortega, LS | 1 |
| Marano, N | 1 |
| Cetron, MS | 1 |
| Phares, CR | 1 |
| Perveen, S | 1 |
| Kumari, D | 1 |
| Singh, K | 1 |
| Sharma, R | 1 |
| Tiberi, S | 1 |
| Utjesanovic, N | 1 |
| Galvin, J | 1 |
| Centis, R | 3 |
| D'Ambrosio, L | 2 |
| van den Boom, M | 1 |
| Zumla, A | 3 |
| Migliori, GB | 6 |
| Lin, M | 1 |
| Chen, YW | 1 |
| Li, YR | 1 |
| Long, LJ | 1 |
| Qi, LY | 1 |
| Cui, TT | 1 |
| Wu, SY | 1 |
| Lin, JY | 1 |
| Wu, T | 1 |
| Yang, YC | 1 |
| Yuan, WH | 1 |
| Wu, GY | 1 |
| Lan, QW | 1 |
| Liu, JQ | 1 |
| Li, YP | 1 |
| Yu, ZY | 1 |
| Guo, XG | 1 |
| Cho, EJ | 1 |
| Kang, MR | 2 |
| Kim, JH | 2 |
| Lee, JI | 1 |
| Son, ES | 1 |
| Park, CH | 1 |
| Aung, WW | 1 |
| Lee, JS | 2 |
| Mutayoba, BK | 1 |
| Ershova, J | 1 |
| Lyamuya, E | 1 |
| Hoelscher, M | 2 |
| Heinrich, N | 1 |
| Kilale, AM | 1 |
| Range, NS | 1 |
| Ngowi, BJ | 1 |
| Ntinginya, NE | 1 |
| Mfaume, SM | 1 |
| Nkiligi, E | 1 |
| Doulla, B | 1 |
| Lyimo, J | 1 |
| Kisonga, R | 1 |
| Kingalu, A | 1 |
| Lema, Y | 1 |
| Kondo, Z | 1 |
| Pletschette, M | 1 |
| Mercier, T | 1 |
| Desfontaine, V | 1 |
| Cruchon, S | 1 |
| Da Silva Pereira Clara, JA | 1 |
| Briki, M | 1 |
| Mazza-Stalder, J | 1 |
| Kajkus, A | 1 |
| Burger, R | 1 |
| Suttels, V | 1 |
| Buclin, T | 1 |
| Opota, O | 1 |
| Koehler, N | 1 |
| Sanchez Carballo, PM | 1 |
| Lange, C | 4 |
| André, P | 1 |
| Decosterd, LA | 1 |
| Choong, E | 1 |
| Syed, RR | 1 |
| Catanzaro, DG | 1 |
| Colman, RE | 1 |
| Cooney, CG | 1 |
| Linger, Y | 1 |
| Kukhtin, AV | 1 |
| Holmberg, RC | 1 |
| Norville, R | 1 |
| Crudu, V | 4 |
| Ciobanu, N | 2 |
| Codreanu, A | 1 |
| Seifert, M | 2 |
| Hillery, N | 1 |
| Chiles, P | 1 |
| Catanzaro, A | 3 |
| Rodwell, TC | 3 |
| Pitso, L | 1 |
| Potgieter, S | 1 |
| Van der Spoel van Dijk, A | 1 |
| Shibabaw, A | 1 |
| Gelaw, B | 1 |
| Kelley, HV | 1 |
| Tesfaye, E | 1 |
| Balada-Llasat, JM | 1 |
| Evans, CA | 2 |
| Torrelles, JB | 1 |
| Wang, SH | 1 |
| Tessema, B | 1 |
| Mvelase, NR | 1 |
| Balakrishna, Y | 1 |
| Lutchminarain, K | 1 |
| Mlisana, K | 2 |
| Sethi, S | 1 |
| Agarwal, P | 2 |
| Khaneja, R | 1 |
| Kumar, N | 2 |
| Chandna, J | 1 |
| Aggarwal, AN | 1 |
| Yadav, R | 1 |
| Ghosh, A | 1 |
| N, S | 1 |
| Saha, S | 1 |
| Ignatius, EH | 1 |
| Swindells, S | 1 |
| Nonghanphithak, D | 1 |
| Kaewprasert, O | 1 |
| Chaiyachat, P | 1 |
| Reechaipichitkul, W | 1 |
| Chaiprasert, A | 1 |
| Faksri, K | 1 |
| Alame Emane, AK | 1 |
| Guo, X | 1 |
| Takiff, HE | 1 |
| Liu, S | 1 |
| Caminero Luna, JA | 1 |
| Chen, J | 1 |
| Peng, P | 1 |
| Du, Y | 1 |
| Ren, Y | 1 |
| Chen, L | 1 |
| Rao, Y | 1 |
| Wang, W | 1 |
| Caminero, JA | 2 |
| Piubello, A | 1 |
| Scardigli, A | 1 |
| Alene, KA | 1 |
| Yi, H | 1 |
| Viney, K | 1 |
| McBryde, ES | 1 |
| Yang, K | 1 |
| Bai, L | 1 |
| Gray, DJ | 1 |
| Clements, ACA | 1 |
| Xu, Z | 1 |
| Igarashi, Y | 1 |
| Chikamatsu, K | 1 |
| Aono, A | 1 |
| Yi, L | 1 |
| Yamada, H | 1 |
| Takaki, A | 1 |
| Mitarai, S | 1 |
| Chesov, D | 1 |
| Schön, T | 1 |
| Heyckendorf, J | 1 |
| Ikram, AI | 1 |
| Satti, ML | 1 |
| Lalani, FK | 1 |
| Zaman, G | 1 |
| Gardezi, AH | 1 |
| Ahmed, P | 1 |
| Akkerman, OW | 1 |
| Grasmeijer, F | 1 |
| de Lange, WCM | 1 |
| Kerstjens, HAM | 1 |
| de Vries, G | 1 |
| Bolhuis, MS | 1 |
| Alffenaar, JW | 1 |
| Frijlink, HW | 1 |
| Smith, G | 1 |
| Gajraj, R | 1 |
| de Zwaan, R | 1 |
| Hagedoorn, P | 1 |
| Dedicoat, M | 1 |
| van Soolingen, D | 1 |
| van der Werf, TS | 1 |
| An, J | 1 |
| Bai, X | 1 |
| Gao, M | 1 |
| Chu, N | 1 |
| Huang, H | 1 |
| Xu, H | 1 |
| Zhang, X | 2 |
| Li, B | 1 |
| Huang, C | 1 |
| Cai, H | 1 |
| Zhang, F | 1 |
| Pang, Y | 1 |
| Li, L | 1 |
| Okumura, M | 1 |
| Yoshiyama, T | 1 |
| Kardan-Yamchi, J | 1 |
| Kazemian, H | 1 |
| Haeili, M | 1 |
| Harati, AA | 1 |
| Amini, S | 1 |
| Feizabadi, MM | 1 |
| Cancino-Muñoz, I | 1 |
| Moreno-Molina, M | 1 |
| Furió, V | 1 |
| Goig, GA | 1 |
| Torres-Puente, M | 1 |
| Chiner-Oms, Á | 1 |
| Villamayor, LM | 1 |
| Sanz, F | 1 |
| Guna-Serrano, MR | 1 |
| Comas, I | 1 |
| Garg, K | 1 |
| Saini, V | 1 |
| Dhillon, R | 1 |
| Imperiale, BR | 1 |
| Zumárraga, MJ | 1 |
| Di Giulio, AB | 1 |
| Cataldi, AA | 1 |
| Morcillo, NS | 1 |
| Yu, XL | 1 |
| Wen, ZL | 1 |
| Chen, GZ | 1 |
| Li, R | 1 |
| Ding, BB | 1 |
| Yao, YF | 1 |
| Wu, H | 1 |
| Guo, XK | 1 |
| Wang, HH | 1 |
| Zhang, SL | 1 |
| Zignol, M | 1 |
| Dara, M | 1 |
| Dean, AS | 1 |
| Falzon, D | 1 |
| Dadu, A | 1 |
| Kremer, K | 1 |
| Hoffmann, H | 1 |
| Hoffner, S | 1 |
| Floyd, K | 1 |
| Lombardi, G | 1 |
| Dal Monte, P | 1 |
| Denicolò, A | 1 |
| Tadolini, M | 1 |
| Martelli, G | 1 |
| Bacchi Reggiani, ML | 1 |
| Viale, P | 1 |
| Landini, MP | 1 |
| Riccardi, G | 1 |
| Pasca, MR | 1 |
| Lan, Y | 1 |
| Lam, JT | 1 |
| Siu, GK | 1 |
| Yam, WC | 1 |
| Mason, AJ | 1 |
| Lam, JK | 1 |
| Dymova, MA | 1 |
| Cherednichenko, AG | 1 |
| Alkhovik, OI | 1 |
| Khrapov, EA | 1 |
| Petrenko, TI | 1 |
| Filipenko, ML | 1 |
| Porvaznik, I | 1 |
| Mokry, J | 1 |
| Solovic, I | 1 |
| Ajbani, K | 1 |
| Lin, SY | 2 |
| Rodrigues, C | 2 |
| Nguyen, D | 1 |
| Arroyo, F | 1 |
| Kaping, J | 1 |
| Jackson, L | 1 |
| Garfein, RS | 2 |
| Catanzaro, D | 2 |
| Eisenach, K | 1 |
| Victor, TC | 3 |
| Gler, MT | 1 |
| Ismail, N | 1 |
| Desmond, E | 1 |
| Lee, YS | 1 |
| Jung, H | 1 |
| Choi, SB | 1 |
| Jo, KW | 1 |
| Shim, TS | 1 |
| Seung, KJ | 1 |
| Keshavjee, S | 1 |
| Rich, ML | 1 |
| Rienthong, S | 1 |
| Boonin, C | 1 |
| Chaiyasirinrote, B | 1 |
| Satproedprai, N | 1 |
| Mahasirimongkol, S | 1 |
| Yoshida, H | 1 |
| Kondo, Y | 1 |
| Namwat, C | 1 |
| Rienthong, D | 1 |
| Niehaus, AJ | 1 |
| Gandhi, NR | 2 |
| Mathema, B | 2 |
| Brust, JC | 1 |
| Manika, K | 1 |
| Chatzika, K | 1 |
| Papaioannou, M | 1 |
| Kontou, P | 1 |
| Boutou, A | 1 |
| Zarogoulidis, K | 1 |
| Kioumis, I | 1 |
| Chen, Y | 1 |
| Zhao, B | 1 |
| Liu, HC | 1 |
| Sun, Q | 1 |
| Zhao, XQ | 1 |
| Liu, ZG | 1 |
| Wan, KL | 1 |
| Zhao, LL | 1 |
| Martínez, LM | 1 |
| Castro, GP | 1 |
| Guerrero, MI | 1 |
| Sibbald, B | 1 |
| Huang, ZK | 1 |
| Luo, Q | 1 |
| Qing, C | 1 |
| Deng, YT | 1 |
| Xiong, GL | 1 |
| Li, JM | 1 |
| Nam, KW | 1 |
| Jang, WS | 1 |
| Jyoti, MA | 1 |
| Kim, S | 1 |
| Lee, BE | 1 |
| Song, HY | 1 |
| Shi, T | 1 |
| Zhang, Z | 1 |
| Dai, F | 1 |
| Zhou, Q | 1 |
| He, Q | 1 |
| Luo, F | 1 |
| Hou, T | 1 |
| Xu, J | 1 |
| Singhal, P | 1 |
| Dixit, P | 1 |
| Singh, P | 1 |
| Jaiswal, I | 1 |
| Singh, M | 1 |
| Jain, A | 1 |
| Zhang, LL | 1 |
| Yang, H | 1 |
| Xiao, HP | 1 |
| Lu, JM | 1 |
| Sha, W | 1 |
| Zhang, Q | 1 |
| Namburete, EI | 1 |
| Tivane, I | 1 |
| Lisboa, M | 1 |
| Passeri, M | 1 |
| Pocente, R | 1 |
| Ferro, JJ | 1 |
| Harrison, LH | 1 |
| Bollela, VR | 1 |
| Georghiou, SB | 1 |
| Jackson, RL | 1 |
| McNaughton, A | 1 |
| Blackmore, T | 1 |
| McNaughton, H | 1 |
| Dookie, N | 1 |
| Sturm, AW | 3 |
| Moodley, P | 3 |
| Chakravorty, S | 1 |
| Roh, SS | 1 |
| Glass, J | 1 |
| Smith, LE | 1 |
| Simmons, AM | 1 |
| Lund, K | 1 |
| Lokhov, S | 1 |
| Liu, X | 1 |
| Xu, P | 1 |
| Zhang, G | 1 |
| Via, LE | 1 |
| Shen, Q | 1 |
| Ruan, X | 1 |
| Yuan, X | 1 |
| Zhu, HZ | 1 |
| Viazovkina, E | 1 |
| Shenai, S | 1 |
| Rowneki, M | 1 |
| Barry, CE | 1 |
| Gao, Q | 1 |
| Persing, D | 1 |
| Kwiatkawoski, R | 1 |
| Jones, M | 1 |
| Gall, A | 1 |
| Alland, D | 1 |
| Vashistha, H | 1 |
| Hanif, M | 2 |
| Saini, S | 1 |
| Sharma, S | 1 |
| Sidiq, Z | 1 |
| Ahmed, V | 1 |
| Dubey, M | 1 |
| Chopra, KK | 1 |
| Shrivastava, D | 1 |
| Nguyen, HQ | 1 |
| Nguyen, NV | 1 |
| Contamin, L | 1 |
| Tran, THT | 1 |
| Vu, TT | 1 |
| Nguyen, HV | 1 |
| Nguyen, NLT | 1 |
| Nguyen, ST | 1 |
| Dang, AD | 1 |
| Bañuls, AL | 1 |
| Nguyen, VAT | 1 |
| Murray, S | 1 |
| Mendel, C | 1 |
| Spigelman, M | 1 |
| Bengtson, HN | 1 |
| Homolka, S | 1 |
| Niemann, S | 1 |
| Reis, AJ | 1 |
| da Silva, PE | 1 |
| Gerasimova, YV | 1 |
| Kolpashchikov, DM | 1 |
| Rohde, KH | 1 |
| Park, SK | 1 |
| Kang, H | 1 |
| Cho, JS | 1 |
| Smego, RA | 1 |
| Ano, H | 1 |
| Matsumoto, T | 1 |
| Suetake, T | 1 |
| Nagai, T | 1 |
| Tamura, Y | 1 |
| Takamatsu, I | 1 |
| Iwasaki, T | 1 |
| Matsuoka, H | 1 |
| Sasada, S | 1 |
| Tetsumoto, S | 1 |
| Tsuyuguchi, I | 1 |
| Kusunoki, Y | 1 |
| Takashima, T | 1 |
| Warren, RM | 1 |
| Streicher, EM | 1 |
| Gey van Pittius, NC | 1 |
| Marais, BJ | 1 |
| van der Spuy, GD | 1 |
| Sirgel, F | 1 |
| Donald, PR | 1 |
| van Helden, PD | 1 |
| Ramachandran, R | 1 |
| Nalini, S | 1 |
| Chandrasekar, V | 1 |
| Dave, PV | 1 |
| Sanghvi, AS | 1 |
| Wares, F | 1 |
| Paramasivan, CN | 1 |
| Narayanan, PR | 1 |
| Sahu, S | 1 |
| Parmar, M | 1 |
| Chadha, S | 1 |
| Dewan, P | 1 |
| Chauhan, LS | 1 |
| Dheda, K | 1 |
| Mwaba, P | 1 |
| Bates, M | 1 |
| O'Grady, J | 1 |
| Sotgiu, G | 2 |
| Sun, Z | 1 |
| Zhang, J | 1 |
| Song, H | 1 |
| Tian, M | 1 |
| Zhao, Y | 1 |
| Li, C | 1 |
| Arjomandzadegan, M | 1 |
| Owlia, P | 1 |
| Ranjbar, R | 1 |
| Farazi, AA | 1 |
| Sofian, M | 1 |
| Sadrnia, M | 1 |
| Ghaznavi-Rad, E | 1 |
| Surkova, LK | 1 |
| Titov, LP | 1 |
| Shah, NS | 2 |
| Tayob, N | 1 |
| Connolly, C | 1 |
| Zetola, N | 1 |
| Gandhi, N | 1 |
| Friedland, G | 2 |
| Villar, M | 1 |
| Raymundo, E | 1 |
| Fernandes, L | 1 |
| Barbedo, J | 1 |
| Diogo, N | 1 |
| Ramos, E | 1 |
| Fissette, K | 1 |
| de Rijk, P | 1 |
| Palomino, JC | 1 |
| Martin, A | 1 |
| Toit, K | 1 |
| Mitchell, S | 1 |
| Balabanova, Y | 1 |
| Kummik, T | 1 |
| Nikolayevskyy, V | 1 |
| Drobniewski, F | 1 |
| Leung, EC | 1 |
| Leung, CC | 1 |
| Kam, KM | 1 |
| Yew, WW | 1 |
| Chang, KC | 1 |
| Leung, WM | 1 |
| Tam, CM | 1 |
| Weissman, D | 1 |
| Ramathal, M | 1 |
| Elson, I | 1 |
| Kreiswirth, BN | 1 |
| Shashkina, E | 1 |
| Rothenberg, R | 1 |
| Moll, AP | 1 |
| Porwal, C | 1 |
| Kaushik, A | 1 |
| Makkar, N | 1 |
| Banavaliker, JN | 1 |
| Singla, R | 1 |
| Bhatnagar, AK | 1 |
| Behera, D | 1 |
| Pande, JN | 1 |
| Singh, UB | 1 |
| Besozzi, G | 1 |
| Girardi, E | 1 |
| Kliiman, K | 1 |
| Toungoussova, OS | 1 |
| Ferrara, G | 1 |
| Cirillo, DM | 1 |
| Gori, A | 1 |
| Matteelli, A | 1 |
| Spanevello, A | 1 |
| Codecasa, LR | 1 |
| Raviglione, MC | 1 |
| Zhang, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Global Consortium for Drug-resistant Tuberculosis Diagnostics[NCT02170441] | 1,128 participants (Actual) | Observational | 2012-04-30 | Completed | |||
| Feasibility, Accuracy, and Effect of Point-of-care Xpert MTB/RIF Ultra and Xpert MTB/RIF Ultra Testing in Patients Suspected of Having TB: a Randomised Controlled Trial[NCT03356925] | 1,549 participants (Actual) | Interventional | 2018-02-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for isoniazid and Extensively Drug-Resistant Tuberculosis
| Article | Year |
|---|---|
Tuberculosis drug discovery: Progression and future interventions in the wake of emerging resistance.
Topics: Antitubercular Agents; Diarylquinolines; Drug Therapy, Combination; Ethambutol; Extensively Drug-Res | 2022 |
Drug resistant TB - latest developments in epidemiology, diagnostics and management.
Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Mycobacterium tub | 2022 |
Systematic evaluation of line probe assays for the diagnosis of tuberculosis and drug-resistant tuberculosis.
Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Microbial Sensiti | 2022 |
Are We There Yet? Short-Course Regimens in TB and HIV: From Prevention to Treatment of Latent to XDR TB.
Topics: Anti-HIV Agents; Antitubercular Agents; Drug Interactions; Extensively Drug-Resistant Tuberculosis; | 2020 |
Drug resistance, fitness and compensatory mutations in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis | 2021 |
Drug-resistant tuberculosis in the WHO European Region: an analysis of surveillance data.
Topics: Antitubercular Agents; Europe; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Microbial | 2013 |
Trends in discovery of new drugs for tuberculosis therapy.
Topics: Alcohol Oxidoreductases; Animals; Antitubercular Agents; Bacterial Proteins; Drug Discovery; Extensi | 2014 |
Multidrug-Resistant Tuberculosis and Extensively Drug-Resistant Tuberculosis.
Topics: Antitubercular Agents; Child; Coinfection; Community Health Services; Drug Administration Schedule; | 2015 |
Review of multidrug-resistant and extensively drug-resistant TB: global perspectives with a focus on sub-Saharan Africa.
Topics: Africa South of the Sahara; Antitubercular Agents; Asia; Europe, Eastern; Extensively Drug-Resistant | 2010 |
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Drug Resistance, Multiple; Ethambutol; Extensively Dru | 2010 |
Advances in the treatment of tuberculosis.
Topics: Adamantane; AIDS-Related Opportunistic Infections; Animals; Anti-Bacterial Agents; Antitubercular Ag | 2007 |
72 other studies available for isoniazid and Extensively Drug-Resistant Tuberculosis
| Article | Year |
|---|---|
Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; DNA Gyrase; DNA Mutational Analysi | 2010 |
New amino acid esters of salicylanilides active against MDR-TB and other microbes.
Topics: Amino Acids; Anti-Bacterial Agents; Antifungal Agents; Bacteria; Dose-Response Relationship, Drug; D | 2010 |
Identification and development of 2,5-disubstituted oxadiazole as potential candidate for treatment of XDR and MDR tuberculosis.
Topics: Antitubercular Agents; Drug Discovery; Extensively Drug-Resistant Tuberculosis; Hep G2 Cells; Humans | 2012 |
Discovery of the disubstituted oxazole analogues as a novel class anti-tuberculotic agents against MDR- and XDR-MTB.
Topics: Antitubercular Agents; Dioxanes; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tu | 2015 |
Hybrid triazoles: Design and synthesis as potential dual inhibitor of growth and efflux inhibition in tuberculosis.
Topics: Antitubercular Agents; Cells, Cultured; Chemistry Techniques, Synthetic; Drug Design; Drug Evaluatio | 2016 |
Rifampicin and isoniazid drug resistance among patients diagnosed with pulmonary tuberculosis in southwestern Uganda.
Topics: Adult; Aged; Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Female; Humans; Isoniaz | 2021 |
Multidrug-Resistant Tuberculosis in U.S.-Bound Immigrants and Refugees.
Topics: Antitubercular Agents; Emigrants and Immigrants; Extensively Drug-Resistant Tuberculosis; Humans; Is | 2022 |
Evaluation of the MolecuTech
Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Humans; Isoniazid; | 2022 |
The second national anti-tuberculosis drug resistance survey in Tanzania, 2017-2018.
Topics: Antitubercular Agents; Cross-Sectional Studies; Ethambutol; Extensively Drug-Resistant Tuberculosis; | 2022 |
A battery of tandem mass spectrometry assays with stable isotope-dilution for the quantification of 15 anti-tuberculosis drugs and two metabolites in patients with susceptible-, multidrug-resistant- and extensively drug-resistant tuberculosis.
Topics: Antitubercular Agents; Cycloserine; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; Isot | 2022 |
Clinical Evaluation of the XDR-LFC Assay for the Molecular Detection of Isoniazid, Rifampin, Fluoroquinolone, Kanamycin, Capreomycin, and Amikacin Drug Resistance in a Prospective Cohort.
Topics: Amikacin; Antitubercular Agents; Bacterial Proteins; Capreomycin; Drug Resistance, Multiple, Bacteri | 2023 |
Prevalence of isoniazid resistance-conferring mutations associated with multidrug-resistant tuberculosis in Free State Province, South Africa.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Child, Preschool; Drug Res | 2019 |
MDR/XDR-TB Colour Test for drug susceptibility testing of Mycobacterium tuberculosis, Northwest Ethiopia.
Topics: Adolescent; Adult; Antitubercular Agents; Ciprofloxacin; Culture Media; Ethiopia; Extensively Drug-R | 2020 |
Evolving rifampicin and isoniazid mono-resistance in a high multidrug-resistant and extensively drug-resistant tuberculosis region: a retrospective data analysis.
Topics: Adolescent; Adult; Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Female; Humans; I | 2019 |
Second-line Drug Resistance Characterization in
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitubercular Agents; Child; Extensively Drug-Resistant | 2020 |
Survey of drug resistance associated gene mutations in Mycobacterium tuberculosis, ESKAPE and other bacterial species.
Topics: Antitubercular Agents; Bacterial Proteins; Data Curation; Databases, Genetic; DNA, Bacterial; Drug R | 2020 |
Whole-genome sequence analysis and comparisons between drug-resistance mutations and minimum inhibitory concentrations of Mycobacterium tuberculosis isolates causing M/XDR-TB.
Topics: Adult; Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Ethionamide; Extensively Drug- | 2020 |
Challenges and Outlooks in Multi-drug Resistant Tuberculosis.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Humans; | 2017 |
Early detection of multidrug- and pre-extensively drug-resistant tuberculosis from smear-positive sputum by direct sequencing.
Topics: Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; China; Early Diagnosis; Extensiv | 2017 |
Proposal for a standardised treatment regimen to manage pre- and extensively drug-resistant tuberculosis cases.
Topics: Aminosalicylic Acid; Antitubercular Agents; Carbapenems; Clofazimine; Communicable Disease Control; | 2017 |
Treatment outcomes of patients with multidrug-resistant and extensively drug resistant tuberculosis in Hunan Province, China.
Topics: Adult; Antitubercular Agents; China; Cohort Studies; Extensively Drug-Resistant Tuberculosis; Female | 2017 |
Laboratory evaluation of the Anyplex™ II MTB/MDR and MTB/XDR tests based on multiplex real-time PCR and melting-temperature analysis to identify Mycobacterium tuberculosis and drug resistance.
Topics: Antitubercular Agents; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resist | 2017 |
Lack of evidence of isoniazid efficacy for the treatment of MDR/XDR-TB in the presence of the
Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Extensively Drug-Re | 2017 |
Evaluation of Nitrate Reductase Assay for Early Detection of Multi and Extensively Drug Resistance Tuberculosis in our Setup.
Topics: Amikacin; Antitubercular Agents; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Earl | 2018 |
Cross border, highly individualised treatment of a patient with challenging extensively drug-resistant tuberculosis.
Topics: Adult; Antitubercular Agents; Colistin; Diarylquinolines; Drug Synergism; Extensively Drug-Resistant | 2018 |
Antituberculosis drug prescribing for inpatients in a national tuberculosis hospital in China, 2011-2015.
Topics: Antitubercular Agents; China; Drug Prescriptions; Extensively Drug-Resistant Tuberculosis; Hospitals | 2018 |
[EXPERIENCE OF USE OF NEW ANTI-TUBERCULOUS DRUG, DELAMANID IN MULTI- AND EXTENSIVELY DRUG RESISTANT TUBERCULOSIS CASES IN OUR HOSPITAL].
Topics: Adult; Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Female; Humans; Isoniazid; Ma | 2016 |
Expression analysis of 10 efflux pump genes in multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis clinical isolates.
Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Extensively Drug-Re | 2019 |
Cryptic Resistance Mutations Associated With Misdiagnoses of Multidrug-Resistant Tuberculosis.
Topics: Antitubercular Agents; Bacterial Proteins; Diagnostic Errors; Drug Resistance, Multiple, Bacterial; | 2019 |
Isoniazid mono-resistant tuberculosis: Time to take it seriously.
Topics: Adult; Antitubercular Agents; Drug Resistance, Bacterial; Extensively Drug-Resistant Tuberculosis; F | 2019 |
Molecular and phenotypic characterisation of Mycobacterium tuberculosis resistant to anti-tuberculosis drugs.
Topics: Antitubercular Agents; Argentina; Bacterial Typing Techniques; DNA, Bacterial; Drug Resistance, Bact | 2013 |
Molecular characterization of multidrug-resistant Mycobacterium tuberculosis isolated from south-central in China.
Topics: Academic Medical Centers; Alleles; Amino Acid Substitution; Antitubercular Agents; Bacterial Protein | 2014 |
Trend of microbiologically-confirmed tuberculosis in a low-incidence setting with high immigration rates.
Topics: Adult; Aged; Bacterial Typing Techniques; Emigrants and Immigrants; Europe, Eastern; Extensively Dru | 2014 |
Cationic amphipathic D-enantiomeric antimicrobial peptides with in vitro and ex vivo activity against drug-resistant Mycobacterium tuberculosis.
Topics: Antimicrobial Cationic Peptides; Antitubercular Agents; Cells, Cultured; Colony Count, Microbial; Do | 2014 |
Characterization of extensively drug-resistant Mycobacterium tuberculosis isolates circulating in Siberia.
Topics: Adult; Amikacin; Antitubercular Agents; Capreomycin; Cross-Sectional Studies; Drug Resistance, Multi | 2014 |
Classical against molecular-genetic methods for susceptibility testing of antituberculotics.
Topics: Aminoglycosides; Antitubercular Agents; Culture Media; DNA, Bacterial; Drug Resistance, Multiple, Ba | 2015 |
Evaluation of pyrosequencing for detecting extensively drug-resistant Mycobacterium tuberculosis among clinical isolates from four high-burden countries.
Topics: Antitubercular Agents; Bacterial Proteins; Base Sequence; Catalase; DNA Gyrase; DNA-Directed RNA Pol | 2015 |
Performance of REBA MTB-XDR to detect extensively drug-resistant tuberculosis in an intermediate-burden country.
Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuber | 2015 |
Evaluation of a novel line-probe assay for genotyping-based diagnosis of Mycobacterium tuberculosis in Thailand.
Topics: Antibiotics, Antitubercular; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Genotype; Hu | 2015 |
High Prevalence of inhA Promoter Mutations among Patients with Drug-Resistant Tuberculosis in KwaZulu-Natal, South Africa.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; Ethionamide; Extensively Drug-Resistant Tubercu | 2015 |
Rifampicin-moxifloxacin interaction in tuberculosis treatment: a real-life study.
Topics: Adult; Aged; Antitubercular Agents; Drug Interactions; Drug Therapy, Combination; Extensively Drug-R | 2015 |
Prevalence of mutations conferring resistance among multi- and extensively drug-resistant Mycobacterium tuberculosis isolates in China.
Topics: Antitubercular Agents; Bacterial Proteins; Catalase; China; DNA-Directed RNA Polymerases; DNA, Bacte | 2016 |
A molecular platform for the diagnosis of multidrug-resistant and pre-extensively drug-resistant tuberculosis based on single nucleotide polymorphism mutations present in Colombian isolates of Mycobacterium tuberculosis.
Topics: Antibiotics, Antitubercular; Colombia; DNA, Bacterial; Extensively Drug-Resistant Tuberculosis; Fluo | 2016 |
Drug-resistant tuberculosis plagues India.
Topics: Amikacin; Antitubercular Agents; Capreomycin; Extensively Drug-Resistant Tuberculosis; Fluoroquinolo | 2016 |
Evaluation of the direct nitrate reductase assay for rapid detection of extensively drug-resistant tuberculosis.
Topics: Adult; Capreomycin; China; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tubercul | 2016 |
In vitro activity of (-)-deoxypergularinine, on its own and in combination with anti-tubercular drugs, against resistant strains of Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Cynanchum; Drug Resistance, Multiple, Bacterial; Drug Synergism; Extensively | 2016 |
Retrospective Study of 967 Patients With Spinal Tuberculosis.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Antitubercular Agents; Back Pain; Chil | 2016 |
A study on pre-XDR & XDR tuberculosis & their prevalent genotypes in clinical isolates of Mycobacterium tuberculosis in north India.
Topics: Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis; Genotype; Humans; Ind | 2016 |
[Determination of in vitro synergy by a checkerboard method when 3 core antimicrobial agents of the retreatment new scheme combined against MDR-MTB and XDR-MTB].
Topics: Aminosalicylic Acids; Antibiotics, Antitubercular; Drug Synergism; Drug Therapy, Combination; Extens | 2016 |
Drug-resistant tuberculosis in Central Mozambique: the role of a rapid genotypic susceptibility testing.
Topics: Adult; Antitubercular Agents; Drug Resistance, Bacterial; Ethambutol; Extensively Drug-Resistant Tub | 2016 |
Shedding light on the performance of a pyrosequencing assay for drug-resistant tuberculosis diagnosis.
Topics: Antitubercular Agents; Extensively Drug-Resistant Tuberculosis; Fluoroquinolones; Genes, Bacterial; | 2016 |
Comprehensive cost of treating one patient with MDR/pre-XDR-TB in Wellington, New Zealand.
Topics: Adult; Amikacin; Aminosalicylic Acid; Anti-Bacterial Agents; Antitubercular Agents; Bronchoscopy; Cl | 2016 |
Mechanisms of first-line antimicrobial resistance in multi-drug and extensively drug resistant strains of Mycobacterium tuberculosis in KwaZulu-Natal, South Africa.
Topics: Amidohydrolases; Antitubercular Agents; Bacterial Proteins; Catalase; Drug Resistance, Multiple, Bac | 2016 |
Detection of Isoniazid-, Fluoroquinolone-, Amikacin-, and Kanamycin-Resistant Tuberculosis in an Automated, Multiplexed 10-Color Assay Suitable for Point-of-Care Use.
Topics: Alleles; Amikacin; Antitubercular Agents; Automation, Laboratory; DNA, Bacterial; Extensively Drug-R | 2017 |
Rapid detection of extensively drug-resistant (XDR-TB) strains from multidrug-resistant tuberculosis (MDR-TB) cases isolated from smear-negative pulmonary samples in an Intermediate Reference Laboratory in India.
Topics: Antitubercular Agents; Bacterial Typing Techniques; Extensively Drug-Resistant Tuberculosis; Humans; | 2016 |
Quadruple-first line drug resistance in Mycobacterium tuberculosis in Vietnam: What can we learn from genes?
Topics: Antitubercular Agents; Bacterial Proteins; Bacterial Typing Techniques; Catalase; DNA Gyrase; DNA-Di | 2017 |
TB Alliance regimen development for multidrug-resistant tuberculosis.
Topics: Antitubercular Agents; Clinical Protocols; Diarylquinolines; Dose-Response Relationship, Drug; Etham | 2016 |
Multiplex detection of extensively drug resistant tuberculosis using binary deoxyribozyme sensors.
Topics: Biosensing Techniques; DNA, Catalytic; Extensively Drug-Resistant Tuberculosis; Humans; Isoniazid; M | 2017 |
Pulmonary resection combined with isoniazid- and rifampin-based drug therapy for patients with multidrug-resistant and extensively drug-resistant tuberculosis.
Topics: Adult; Antitubercular Agents; Combined Modality Therapy; Drug Administration Schedule; Drug Resistan | 2009 |
Relationship between the isoniazid-resistant mutation katGS315T and the prevalence of MDR-/XDR-TB in Osaka, Japan.
Topics: Cluster Analysis; Cohort Studies; DNA, Bacterial; Extensively Drug-Resistant Tuberculosis; Humans; I | 2008 |
The clinical relevance of Mycobacterial pharmacogenetics.
Topics: Algorithms; Antitubercular Agents; Bacterial Proteins; Catalase; Extensively Drug-Resistant Tubercul | 2009 |
Surveillance of drug-resistant tuberculosis in the state of Gujarat, India.
Topics: Antitubercular Agents; Bacteriological Techniques; Colony Count, Microbial; Drug Resistance, Multipl | 2009 |
Concomitant increases in spectrum and level of drug resistance in Mycobacterium tuberculosis isolates.
Topics: Antitubercular Agents; Drug Resistance, Multiple, Bacterial; Extensively Drug-Resistant Tuberculosis | 2010 |
Prevalence of mutations at codon 463 of katG gene in MDR and XDR clinical isolates of Mycobacterium tuberculosis in Belarus and application of the method in rapid diagnosis.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Bacterial Proteins; Catalase; Codon; Extensively Dru | 2011 |
Spread of extensively drug-resistant tuberculosis in KwaZulu-Natal province, South Africa.
Topics: Antitubercular Agents; Cross-Sectional Studies; Ethambutol; Extensively Drug-Resistant Tuberculosis; | 2011 |
Linezolid safety, tolerability and efficacy to treat multidrug- and extensively drug-resistant tuberculosis.
Topics: Acetamides; Adult; Amikacin; Antitubercular Agents; Capreomycin; Drug-Related Side Effects and Adver | 2011 |
Integrated detection of multi- and extensively drug-resistant tuberculosis using the nitrate reductase assay.
Topics: Antitubercular Agents; Colorimetry; DNA Mutational Analysis; Drug Resistance, Multiple, Bacterial; E | 2012 |
The Colour Test for drug susceptibility testing of Mycobacterium tuberculosis strains.
Topics: Antitubercular Agents; Ciprofloxacin; Color; Drug Resistance, Multiple, Bacterial; Estonia; Extensiv | 2012 |
Transmission of multidrug-resistant and extensively drug-resistant tuberculosis in a metropolitan city.
Topics: Adult; Cities; Cluster Analysis; Cohort Studies; Contact Tracing; Extensively Drug-Resistant Tubercu | 2013 |
Nosocomial transmission of extensively drug-resistant tuberculosis in a rural hospital in South Africa.
Topics: Adult; Antitubercular Agents; Cluster Analysis; Cross Infection; Drug Therapy, Combination; Ethambut | 2013 |
Incidence and risk factors for extensively drug-resistant tuberculosis in Delhi region.
Topics: Adult; Amikacin; Antitubercular Agents; Capreomycin; Ethionamide; Extensively Drug-Resistant Tubercu | 2013 |
Clinical and operational value of the extensively drug-resistant tuberculosis definition.
Topics: Antitubercular Agents; Communicable Diseases; Drug Resistance, Multiple; Extensively Drug-Resistant | 2007 |