isoniazid has been researched along with Epilepsy, Tonic-Clonic in 13 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Epilepsy, Tonic-Clonic: A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 14-yr old previously healthy girl receiving preventive isoniazid therapy who suddenly developed generalized tonic-clonic seizures and coma." | 3.70 | Acute isoniazid neurotoxicity during preventive therapy. ( Gorjup, V; Horvat, M; Martinjak-Dvorsek, I; Noc, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalaci, A | 1 |
| Duru, M | 1 |
| Karazincir, S | 1 |
| Sevinç, TT | 1 |
| Kuvandik, G | 1 |
| Balci, A | 1 |
| NELSON, LG | 1 |
| LISSAC, J | 1 |
| POCIDALO, JJ | 1 |
| SACHS, C | 1 |
| DEVADATTA, S | 1 |
| Kumar, S | 1 |
| Rao, S | 1 |
| Ramiah, I | 1 |
| Jayaram, A | 1 |
| Martinjak-Dvorsek, I | 1 |
| Gorjup, V | 1 |
| Horvat, M | 1 |
| Noc, M | 1 |
| Hashem, N | 1 |
| Shawki, R | 1 |
| Avasthi, R | 1 |
| Jain, AP | 1 |
| Parish, RA | 1 |
| Brownstein, D | 1 |
| Jacques, S | 1 |
| Freshwater, DB | 1 |
| Randle, RE | 1 |
| Shelden, CH | 1 |
| Cambier, J | 1 |
| Houillon, G | 1 |
| Samulak, G | 1 |
| Houillon, P | 1 |
| Seidell, MA | 1 |
1 trial available for isoniazid and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
[Management of a first attack of generalized epilepsy].
Topics: Barbiturates; Brain; Cerebral Angiography; Clinical Trials as Topic; Epilepsy, Tonic-Clonic; Female; | 1974 |
12 other studies available for isoniazid and Epilepsy, Tonic-Clonic
| Article | Year |
|---|---|
Thoracic spine compression fracture during isoniazid-induced seizures: case report.
Topics: Antidotes; Back Pain; Charcoal; Child; Drug Overdose; Epilepsy, Tonic-Clonic; Female; Fractures, Com | 2008 |
GRAND MAL SEIZURES FOLLOWING OVERDOSE OF ISONIAZID. A REPORT OF FOUR CASES.
Topics: Adolescent; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Isoniazid; Liver | 1965 |
[ON A CASE OF ACUTE ISONIAZID INTOXICATION. GRAND MAL EPILEPSY WITH SEVERE METABOLIC ACIDOSIS].
Topics: Acidosis; Epilepsy; Epilepsy, Tonic-Clonic; Isoniazid; Seizures; Toxicology | 1965 |
ISONIAZID-INDUCED ENCEPHALOPATHY.
Topics: Brain Diseases; Drug Therapy; Epilepsy; Epilepsy, Tonic-Clonic; Isoniazid; Peripheral Nervous System | 1965 |
A case of neurotoxicity due to INH.
Topics: Adult; Critical Care; Dose-Response Relationship, Drug; Drug Overdose; Epilepsy, Tonic-Clonic; Human | 1993 |
Acute isoniazid neurotoxicity during preventive therapy.
Topics: Acute Disease; Adolescent; Antitubercular Agents; Coma; Conscious Sedation; Electroencephalography; | 2000 |
Cultured peripheral lymphocytes: one biologic indicator of potential drug hazard.
Topics: Adolescent; Antimony; Antimony Potassium Tartrate; Child; Child, Preschool; Chromosomes, Human; Drug | 1976 |
Phenytoin--isoniazid interaction.
Topics: Adult; Cerebellar Ataxia; Drug Synergism; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; | 1989 |
Emergency department management of children with acute isoniazid poisoning.
Topics: Adolescent; Child; Diazepam; Emergencies; Epilepsies, Partial; Epilepsy, Temporal Lobe; Epilepsy, To | 1986 |
Supratentorial tuberculoma: a case report and review.
Topics: Adult; Brain Diseases; Cerebral Angiography; Dexamethasone; Diagnosis, Differential; Electroencephal | 1974 |
[Apropos of a case of Gayet-Wernicke's encephalopathy in a latent epileptic. Centrophenoxine and thiamine. Electro-clinical contraindications].
Topics: Acetates; Adult; Central Nervous System Stimulants; Epilepsy, Tonic-Clonic; Humans; Hydroxocobalamin | 1968 |
Isoniazid induced life-threatening neurologic reaction in an allergic individual.
Topics: Adult; Anaphylaxis; Asthma; Bronchitis; Central Nervous System Diseases; Chemical and Drug Induced L | 1970 |