isoniazid has been researched along with Diarrhea in 16 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that antituberculous drug disposition is altered in patients with AIDS, we studied the steady-state pharmacokinetics of isoniazid (300 mg/d), rifampin (600 mg/d), and pyrazinamide (1,500 mg/d) in 29 adults (14 patients infected with human immunodeficiency virus [HIV] and 15 non-HIV-infected patients) with tuberculosis in Nairobi, Kenya." | 5.08 | Pharmacokinetics of antimycobacterial drugs in patients with tuberculosis, AIDS, and diarrhea. ( Aoki, FY; Choudhri, SH; Gathua, S; Hawken, M; Long, R; Minyiri, GO; Sahai, J; Sitar, DS; Watkins, W, 1997) |
| " Peak drug exposure to isoniazid was lower in patients with diarrhea." | 3.69 | Reduced plasma concentrations of antituberculosis drugs in patients with HIV infection. ( Cameron, DW; Gallicano, K; Garber, G; Oliveras, L; Rachlis, A; Sahai, J; Seguin, I; Swick, L; Tailor, S; Walker, S, 1997) |
| "Pyrazinamide, an antituberculous drug discovered in 1952, was first considered as a toxic drug." | 2.36 | [Toxicity of pyrazinamide in antituberculous treatments (author's transl)]. ( Perdrizet, S; Pretet, S, 1980) |
| " Diarrhea and alopecia were the clinical signs observed in animals dosed with IQG-607 for 90 days." | 1.46 | Toxicological profile of IQG-607 after single and repeated oral administration in minipigs: An essential step towards phase I clinical trial. ( Basso, LA; Campos, AH; Campos, MM; Cintra, L; Dadda, A; Machado, P; Mafra, ACCN; Rodrigues-Junior, VS; Santos, DS, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (43.75) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodrigues-Junior, VS | 1 |
| Cintra, L | 1 |
| Machado, P | 1 |
| Dadda, A | 1 |
| Basso, LA | 1 |
| Mafra, ACCN | 1 |
| Campos, AH | 1 |
| Campos, MM | 1 |
| Santos, DS | 1 |
| Cerezo Lajas, A | 1 |
| Caminero Luna, JA | 1 |
| Rodríguez Guzmán, MDC | 1 |
| de Miguel Díez, J | 1 |
| Hara, M | 1 |
| Hatta, T | 1 |
| Ohtani, M | 1 |
| Segawa, H | 1 |
| Ueno, R | 1 |
| Sawada, K | 1 |
| Opondo, EA | 1 |
| SCHOENE, W | 1 |
| WANAT-KONDRATOWICZ, W | 1 |
| KAWAGUCHI, M | 1 |
| AOJI, I | 1 |
| KINUGASA, S | 1 |
| SANO, Y | 1 |
| Pretet, S | 1 |
| Perdrizet, S | 1 |
| Sheehan, CJ | 1 |
| Choudhri, SH | 1 |
| Hawken, M | 1 |
| Gathua, S | 1 |
| Minyiri, GO | 1 |
| Watkins, W | 1 |
| Sahai, J | 2 |
| Sitar, DS | 1 |
| Aoki, FY | 1 |
| Long, R | 1 |
| Gallicano, K | 1 |
| Swick, L | 1 |
| Tailor, S | 1 |
| Garber, G | 1 |
| Seguin, I | 1 |
| Oliveras, L | 1 |
| Walker, S | 1 |
| Rachlis, A | 1 |
| Cameron, DW | 1 |
| Ishikawa, Y | 1 |
| Mwinga, A | 1 |
| Hosp, M | 1 |
| Zulu, I | 1 |
| Farthing, MJ | 1 |
| Mulambo, S | 1 |
| Kelly, P | 1 |
| Tabrisky, J | 1 |
| Lindstrom, RR | 1 |
| Peters, R | 1 |
| Lachman, RS | 1 |
| Somner, AR | 1 |
| Selkon, JB | 1 |
| Walton, M | 1 |
| White, AB | 1 |
| Devulder, B | 1 |
| Lelievre, G | 1 |
| Capier, P | 1 |
| Tacquet, A | 1 |
2 reviews available for isoniazid and Diarrhea
| Article | Year |
|---|---|
[Toxicity of pyrazinamide in antituberculous treatments (author's transl)].
Topics: Chemical and Drug Induced Liver Injury; Diarrhea; Drug Eruptions; Gout; Humans; Isoniazid; Nausea; P | 1980 |
[Niacin deficiency disease(pellagra)].
Topics: Alcoholism; Dementia; Dermatitis; Diagnosis, Differential; Diarrhea; Humans; Isoniazid; Niacin; Pell | 2000 |
1 trial available for isoniazid and Diarrhea
| Article | Year |
|---|---|
Pharmacokinetics of antimycobacterial drugs in patients with tuberculosis, AIDS, and diarrhea.
Topics: Adult; AIDS-Related Opportunistic Infections; Antitubercular Agents; Biological Availability; Diarrh | 1997 |
13 other studies available for isoniazid and Diarrhea
| Article | Year |
|---|---|
Toxicological profile of IQG-607 after single and repeated oral administration in minipigs: An essential step towards phase I clinical trial.
Topics: Administration, Oral; Alopecia; Animals; Antitubercular Agents; Diarrhea; Drug Evaluation, Preclinic | 2017 |
Antituberculosis Treatment in a Patient with Celiac Disease.
Topics: Aged; Antitubercular Agents; Celiac Disease; Diarrhea; Diet, Gluten-Free; Drug Compounding; Drug Sub | 2018 |
[A case of tuberculous peritonitis in a hemodialysis patient revealed by severe diarrhea and stomachache].
Topics: Abdominal Pain; Antitubercular Agents; Biomarkers; CA-125 Antigen; Diagnosis, Differential; Diarrhea | 2013 |
Diagnostic challenges of intestinal tuberculosis in a patient with chronic diarrhoea: case report.
Topics: Adult; Antitubercular Agents; Chronic Disease; Diarrhea; Ethambutol; Humans; Isoniazid; Laparotomy; | 2008 |
[INTOLERANCE PHENOMENA IN ISONIAZID USE].
Topics: Diabetes Mellitus; Diarrhea; Drug Hypersensitivity; Isoniazid; Toxicology; Tuberculosis; Tuberculosi | 1963 |
[SIDE-EFFECTS IN TUBERCULOSIS TREATMENT WITH CLASSICAL ANTIBACTERIAL DRUGS].
Topics: Alcoholism; Anti-Bacterial Agents; Diarrhea; Drug Hypersensitivity; Feeding and Eating Disorders; He | 1963 |
[CASE OF ENCEPHALOMYELORADICULONEURITIS FOLLOWING DIARRHEA].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Diarrhea; Drug Therapy; Encephalitis; Isoniazid; Kanamyci | 1964 |
Sorbitol isn't always a sweet deal.
Topics: Acquired Immunodeficiency Syndrome; Diarrhea; Drug Combinations; Female; Humans; Infant; Isoniazid; | 1993 |
Reduced plasma concentrations of antituberculosis drugs in patients with HIV infection.
Topics: Adult; Aged; Antitubercular Agents; Case-Control Studies; Diarrhea; Ethambutol; Female; HIV Infectio | 1997 |
Tuberculosis preventative treatment also prevented diarrhoea in HIV-infected patients in Zambia.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Diarrhea; Drug Therapy, Combination; Follow-Up S | 2002 |
Tuberculous enteritis. Review of a protean disease.
Topics: Adult; Aged; Child; Diagnosis, Differential; Diarrhea; Emigration and Immigration; Enteritis; Ethamb | 1975 |
Drug resistant pulmonary tuberculosis treated with ethambutol and rifampicin in North East England.
Topics: Aged; Aminosalicylic Acids; Diarrhea; Drug Resistance, Microbial; England; Ethambutol; Headache; Hum | 1973 |
[Letter: Acute kidney failure due to rifampicin].
Topics: Acute Kidney Injury; Diarrhea; Ethionamide; Female; Humans; Isoniazid; Middle Aged; Renal Dialysis; | 1973 |