isoniazid has been researched along with Diabetes Mellitus in 51 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the study was to compare plasma concentrations of rifampicin (RMP), isoniazid (INH) and pyrazinamide (PZA) between tuberculosis (TB) patients with and without diabetes mellitus (DM)." | 5.24 | Anti-tuberculosis drug concentrations in tuberculosis patients with and without diabetes mellitus. ( Chandrasekaran, V; Kannan, T; Kumar, AK; Lavanya, J; Murali, AL; Ramachandran, G; Sudha, V; Swaminathan, S, 2017) |
| "This review will introduce pharmacokinetic parameters for key anti-TB drugs, as well as the indications and limitations of measuring these parameters in clinical practice." | 2.50 | Understanding pharmacokinetics to improve tuberculosis treatment outcome. ( Heysell, SK; Reynolds, J, 2014) |
| "In the cases of Crohn's disease and rheumatoid arthritis administered anti-TNF-alpha, chemoprophylaxis is necessary for those who show healing of TB despite those who are suspected of having TB infection by a tuberculin test." | 2.42 | [Measures for tuberculosis in compromised hosts--mainly on chemoprophylaxis]. ( Yamagishi, F, 2003) |
| "Isoniazid resistance was significantly associated with the Beijing genotype of Lineage 2 (19." | 1.72 | Association between Mycobacterium tuberculosis genotype and diabetes mellitus/hypertension: a molecular study. ( Chaiprasert, A; Chen, H; Chongsuvivatwong, V; Guo, S; Lei, S; Li, J; Luo, R; McNeil, E; Ou, W; Palittapongarnpim, P; Qin, W; Surachat, K; Zhang, S, 2022) |
| "2% had ≥1 adverse drug reactions (P < ." | 1.62 | Completion Rate and Safety of Programmatic Screening and Treatment for Latent Tuberculosis Infection in Elderly Patients With Poorly Controlled Diabetic Mellitus: A Prospective Multicenter Study. ( Cheng, MH; Chin, CS; Chong, IW; Huang, HL; Huang, WC; Lee, IT; Lee, MR; Lin, KD; Liu, SS; Lu, PL; Sheu, CC; Wang, JY, 2021) |
| "There is a need for individualized dosing of isoniazid and rifampicin based on plasma concentration measurements (therapeutic drug monitoring) and for clinical trials on higher doses of these TB drugs in patients with TB and DM." | 1.51 | Effect of diabetes mellitus on TB drug concentrations in Tanzanian patients. ( Aarnoutse, RE; Boeree, MJ; Burger, DM; Colbers, A; Irongo, CF; Kibiki, GS; Mtabho, CM; Semvua, HH; Tostmann, A; van Crevel, R; van den Boogaard, J; van der Ven, AJAM, 2019) |
| "Isoniazid levels were analyzed at 2 and 6 h after drug intake using liquid chromatography mass spectrometric methods." | 1.40 | Effects of dosage, comorbidities, and food on isoniazid pharmacokinetics in Peruvian tuberculosis patients. ( Ardrey, A; Davies, G; Jave, O; López-Romero, SL; Moore, DA; Requena-Méndez, A; Ward, SA; Waterhouse, D, 2014) |
| "Diabetes mellitus was documented in 57/135 (42." | 1.35 | Radiographic manifestations of culture-positive pulmonary tuberculosis: cavitary or non-cavitary? ( Al-Tawfiq, JA; Saadeh, BM, 2009) |
| "Family and personal history of mental illness are also predisposing factors." | 1.31 | [Behavioral disorders after treatment with isoniazid]. ( Djibo, A; Lawan, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (58.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (9.80) | 29.6817 |
| 2010's | 10 (19.61) | 24.3611 |
| 2020's | 6 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Olomi, W | 1 |
| Andia Biraro, I | 1 |
| Kilonzo, K | 1 |
| Te Brake, L | 1 |
| Kibirige, D | 1 |
| Chamba, N | 1 |
| Elias Ntinginya, N | 1 |
| Sabi, I | 1 |
| Critchley, J | 1 |
| Sharples, K | 1 |
| Hill, PC | 1 |
| Van Crevel, R | 2 |
| Guo, S | 1 |
| Lei, S | 1 |
| Palittapongarnpim, P | 1 |
| McNeil, E | 1 |
| Chaiprasert, A | 1 |
| Li, J | 1 |
| Chen, H | 1 |
| Ou, W | 1 |
| Surachat, K | 1 |
| Qin, W | 1 |
| Zhang, S | 1 |
| Luo, R | 1 |
| Chongsuvivatwong, V | 1 |
| Mary Rebecca, Y | 1 |
| Sudha, V | 2 |
| Bharathiraja, T | 1 |
| Kannan, T | 2 |
| Lavanya, J | 2 |
| Hemanth Kumar, AK | 1 |
| Trivedi, P | 1 |
| Chaturvedi, V | 1 |
| Mtabho, CM | 1 |
| Semvua, HH | 1 |
| van den Boogaard, J | 1 |
| Irongo, CF | 1 |
| Boeree, MJ | 1 |
| Colbers, A | 1 |
| Burger, DM | 1 |
| van der Ven, AJAM | 1 |
| Kibiki, GS | 1 |
| Tostmann, A | 1 |
| Aarnoutse, RE | 1 |
| Galvão, FES | 1 |
| Fonseca, AAD | 1 |
| Pinto, ACG | 1 |
| da Paixão, TP | 1 |
| Albério, CAA | 1 |
| Vieira, JLF | 1 |
| Huang, HL | 1 |
| Huang, WC | 1 |
| Lin, KD | 1 |
| Liu, SS | 1 |
| Lee, MR | 1 |
| Cheng, MH | 1 |
| Chin, CS | 1 |
| Lu, PL | 1 |
| Sheu, CC | 1 |
| Wang, JY | 1 |
| Lee, IT | 1 |
| Chong, IW | 1 |
| Alfarisi, O | 1 |
| Mave, V | 1 |
| Gaikwad, S | 1 |
| Sahasrabudhe, T | 1 |
| Ramachandran, G | 2 |
| Kumar, H | 1 |
| Gupte, N | 1 |
| Kulkarni, V | 1 |
| Deshmukh, S | 1 |
| Atre, S | 1 |
| Raskar, S | 1 |
| Lokhande, R | 1 |
| Barthwal, M | 1 |
| Kakrani, A | 1 |
| Chon, S | 1 |
| Gupta, A | 1 |
| Golub, JE | 1 |
| Dooley, KE | 1 |
| Harries, AD | 1 |
| Lin, Y | 1 |
| Kumar, AMV | 1 |
| Satyanarayana, S | 1 |
| Zachariah, R | 1 |
| Dlodlo, RA | 1 |
| Anuwatnonthakate, A | 1 |
| Whitehead, SJ | 1 |
| Varma, JK | 1 |
| Silachamroon, U | 1 |
| Kasetjaroen, Y | 1 |
| Moolphate, S | 1 |
| Limsomboon, P | 1 |
| Inyaphong, J | 1 |
| Suriyon, N | 1 |
| Kavinum, S | 1 |
| Chiengson, N | 1 |
| Tunteerapat, P | 1 |
| Kaewkungwal, J | 1 |
| Reynolds, J | 1 |
| Heysell, SK | 1 |
| Requena-Méndez, A | 1 |
| Davies, G | 1 |
| Waterhouse, D | 1 |
| Ardrey, A | 1 |
| Jave, O | 1 |
| López-Romero, SL | 1 |
| Ward, SA | 1 |
| Moore, DA | 1 |
| Gómez-Gómez, A | 1 |
| Magaña-Aquino, M | 1 |
| López-Meza, S | 1 |
| Aranda-Álvarez, M | 1 |
| Díaz-Ornelas, DE | 1 |
| Hernández-Segura, MG | 1 |
| Salazar-Lezama, MÁ | 1 |
| Castellanos-Joya, M | 1 |
| Noyola, DE | 1 |
| Baghaei, P | 1 |
| Tabarsi, P | 1 |
| Javanmard, P | 1 |
| Farnia, P | 1 |
| Marjani, M | 1 |
| Moniri, A | 1 |
| Masjedi, MR | 1 |
| Velayati, AA | 1 |
| Kumar, AK | 1 |
| Chandrasekaran, V | 1 |
| Murali, AL | 1 |
| Swaminathan, S | 1 |
| Al-Tawfiq, JA | 1 |
| Saadeh, BM | 1 |
| Fortún, J | 1 |
| Martín-Dávila, P | 1 |
| Navas, E | 1 |
| López-Vélez, R | 1 |
| Pintado, V | 1 |
| Cobo, J | 1 |
| González, A | 1 |
| Bonilla, M | 1 |
| Aneiros, V | 1 |
| Gómez-Mampaso, E | 1 |
| Moreno, S | 1 |
| LUNTZ, GR | 1 |
| SMITH, SG | 1 |
| SPIEGELMAN, AR | 1 |
| QUIGLEY, TJ | 1 |
| POLOSA, P | 1 |
| PAULY, W | 1 |
| ORLOWSKI, EH | 1 |
| IRSKENS, KJ | 1 |
| LA ROSA, F | 1 |
| PACE, L | 1 |
| PFAFFENBERG, R | 5 |
| JAHLER, H | 2 |
| IWAINSKY, H | 3 |
| JAEHLER, H | 2 |
| SIEGEL, D | 1 |
| DICKSON, I | 1 |
| SCHILLING, I | 1 |
| BROIDE, L | 1 |
| ORSI, A | 1 |
| SCHOENE, W | 1 |
| RICCHETTI, C | 1 |
| CRISCI, J | 1 |
| DEENSTRA, H | 1 |
| YAMAMURA, Y | 1 |
| COTTIN, S | 1 |
| COZAN, R | 1 |
| VERAN, P | 1 |
| FILLA, E | 1 |
| COMENALE, D | 1 |
| ROSSI, F | 1 |
| EVANS, DA | 1 |
| KNAPP, A | 1 |
| BOUCETTA, MO | 1 |
| Yamagishi, F | 1 |
| Wada, M | 1 |
| Djibo, A | 1 |
| Lawan, A | 1 |
| Sahn, SA | 1 |
| Lakshminarayan, S | 1 |
| Chiancone, FM | 1 |
| Tschudi-Steiner, I | 1 |
| Pyle, MM | 1 |
| Ruszel, B | 1 |
| Tybusz, R | 1 |
| Lukjan, Z | 1 |
| Rogowski, F | 1 |
| Oleński, J | 1 |
| Mattila, MJ | 1 |
| Tiitinen, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double Blind Placebo Controlled Trial of Rifapentine and Isoniazid for Prevention of Tuberculosis in People With Diabetes[NCT04600167] | Phase 3 | 3,000 participants (Anticipated) | Interventional | 2022-06-17 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for isoniazid and Diabetes Mellitus
| Article | Year |
|---|---|
How can integrated care and research assist in achieving the SDG targets for diabetes, tuberculosis and HIV/AIDS?
Topics: Anti-Retroviral Agents; Antitubercular Agents; Biomedical Research; Delivery of Health Care, Integra | 2018 |
Understanding pharmacokinetics to improve tuberculosis treatment outcome.
Topics: Antitubercular Agents; Diabetes Mellitus; Drug Monitoring; Ethambutol; HIV Infections; Humans; Isoni | 2014 |
[Measures for tuberculosis in compromised hosts--mainly on chemoprophylaxis].
Topics: Antibiotic Prophylaxis; Antitubercular Agents; Arthritis, Rheumatoid; Collagen Diseases; Crohn Disea | 2003 |
[Adverse effects of important long-term-therapeutics].
Topics: Acidosis; Animals; Antidepressive Agents; Antitubercular Agents; Biguanides; Central Nervous System; | 1970 |
2 trials available for isoniazid and Diabetes Mellitus
| Article | Year |
|---|---|
Anti-tuberculosis drug concentrations in tuberculosis patients with and without diabetes mellitus.
Topics: Adult; Antitubercular Agents; Diabetes Mellitus; Female; Humans; Isoniazid; Male; Middle Aged; Pyraz | 2017 |
Clinical applications of ethambutol.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Child, Preschool; Clinical Trials as Topic; Cycloseri | 1969 |
45 other studies available for isoniazid and Diabetes Mellitus
| Article | Year |
|---|---|
Tuberculosis Preventive Therapy for People With Diabetes Mellitus.
Topics: Diabetes Mellitus; Humans; Isoniazid; Tuberculosis | 2022 |
Association between Mycobacterium tuberculosis genotype and diabetes mellitus/hypertension: a molecular study.
Topics: Cross-Sectional Studies; Diabetes Mellitus; Genotype; Humans; Hypertension; Isoniazid; Mycobacterium | 2022 |
Urinary excretion of metformin in diabetic patients with and without tuberculosis.
Topics: Antitubercular Agents; Diabetes Mellitus; Humans; India; Isoniazid; Metformin; Pyrazinamide; Tubercu | 2023 |
Interactive effect of oral anti-hyperglycaemic or anti-hypertensive drugs on the inhibitory and bactericidal activity of first line anti-TB drugs against M. tuberculosis.
Topics: Antihypertensive Agents; Antitubercular Agents; Diabetes Mellitus; Ethambutol; Humans; Hypertension; | 2023 |
Effect of diabetes mellitus on TB drug concentrations in Tanzanian patients.
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Diabetes Complications; Diabetes Mellitus; Fe | 2019 |
No significant influence of diabetic mellitus on isoniazid plasma levels in patients under treatment for tuberculosis.
Topics: Antitubercular Agents; Diabetes Mellitus; Humans; Isoniazid; Patients; Plasma; Rifampin; Tuberculosi | 2020 |
Completion Rate and Safety of Programmatic Screening and Treatment for Latent Tuberculosis Infection in Elderly Patients With Poorly Controlled Diabetic Mellitus: A Prospective Multicenter Study.
Topics: Aged; Antitubercular Agents; Diabetes Mellitus; Drug Therapy, Combination; Humans; Isoniazid; Latent | 2021 |
Effect of Diabetes Mellitus on the Pharmacokinetics and Pharmacodynamics of Tuberculosis Treatment.
Topics: Adult; Antitubercular Agents; Diabetes Mellitus; Female; Glycated Hemoglobin; Humans; Isoniazid; Mal | 2018 |
Effect of mycobacterial drug resistance patterns on patients' survival: a cohort study in Thailand.
Topics: Adolescent; Adult; Aged; Anti-Retroviral Agents; Antitubercular Agents; Child; Child, Preschool; Dia | 2013 |
Effects of dosage, comorbidities, and food on isoniazid pharmacokinetics in Peruvian tuberculosis patients.
Topics: Adolescent; Adult; Anti-HIV Agents; Antitubercular Agents; Area Under Curve; Comorbidity; Diabetes M | 2014 |
Diabetes and Other Risk Factors for Multi-drug Resistant Tuberculosis in a Mexican Population with Pulmonary Tuberculosis: Case Control Study.
Topics: Adult; Ambulatory Care Facilities; Antibiotics, Antitubercular; Bacterial Typing Techniques; Case-Co | 2015 |
Impact of diabetes mellitus on tuberculosis drug resistance in new cases of tuberculosis.
Topics: Adult; Aged; Case-Control Studies; Diabetes Mellitus; Drug Resistance, Bacterial; Female; Humans; Ir | 2016 |
Radiographic manifestations of culture-positive pulmonary tuberculosis: cavitary or non-cavitary?
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Comorbidity; Diabetes Mellitus; Drug Resistan | 2009 |
Drug-induced hypoglycaemia.
Topics: Anti-Bacterial Agents; Blood Glucose; Carbamates; Dextropropoxyphene; Diabetes Mellitus; Disopyramid | 2009 |
Changes in the epidemiology of tuberculosis: the influence of international migration flows.
Topics: Adult; Africa; Age Distribution; Aged; Aged, 80 and over; Antitubercular Agents; Comorbidity; Diabet | 2011 |
Effect of isoniazid on carbohydrate metabolism in controls and diabetics.
Topics: Blood Glucose; Carbohydrate Metabolism; Carbohydrates; Diabetes Mellitus; Isoniazid; Niacin; Nicotin | 1953 |
Isonicotinic acid hydrazide in the tuberculous diabetic.
Topics: Diabetes Complications; Diabetes Mellitus; Isoniazid; Niacin; Nicotinic Acids; Tuberculosis | 1952 |
[Behavior of the glycemic curve in diabetic treated with a single intravenous injection of isonicotinic acid hydrazide].
Topics: Blood Glucose; Diabetes Mellitus; Humans; Injections, Intravenous; Isoniazid; Niacin; Nicotinic Acid | 1953 |
[Diabetic metabolic disorders occurring during thiosemicarbazone and isoniazid therapy].
Topics: Diabetes Mellitus; Isoniazid; Niacin; Nicotinic Acids; Thiosemicarbazones; Tuberculosis; Tuberculosi | 1953 |
[Clinical study of the effect of isoniazid on the carbohydrate metabolism tuberculous diabetics].
Topics: Carbohydrate Metabolism; Carbohydrates; Diabetes Complications; Diabetes Mellitus; Humans; Isoniazid | 1954 |
[Isoniazid in the treatment of diabetic tuberculosis].
Topics: Diabetes Complications; Diabetes Mellitus; Isoniazid; Niacin; Nicotinic Acids; Tuberculosis | 1954 |
[Study of the effect of isonicotinic hydrazide on blood sugar levels in diabetics].
Topics: Anti-Bacterial Agents; Blood Glucose; Diabetes Mellitus; Humans; Isoniazid | 1957 |
[Isoniazid & recurrence of tuberculosis in diabetics].
Topics: Diabetes Complications; Diabetes Mellitus; Humans; Isoniazid; Tuberculosis; Tuberculosis, Pulmonary | 1958 |
[On metabolism of isonicotinic acid hydrazide (INH) and alpha-keto acids in tuberculous diabetics].
Topics: Diabetes Mellitus; Glutarates; Humans; Isoniazid; Keto Acids; Tuberculosis | 1960 |
Glycosuria and diabetes mellitus following I.N.A.H. therapy.
Topics: Diabetes Mellitus; Glycosuria; Humans; Isoniazid | 1962 |
[INH metabolism and the course of tuberculosis in diabetics].
Topics: Diabetes Mellitus; Humans; Isoniazid; Tuberculosis | 1963 |
[Tuberculosis in diabetes mellitus].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Diabetes Mellitus; Isoniazid; Tuberculosis | 1962 |
[THE EFFECT OF THE DURATION OF TREATMENT ON INH METABOLISM].
Topics: Diabetes Mellitus; Humans; Isoniazid; Metabolism | 1963 |
[PULMONARY TUBERCULOSIS AND METACORTICOID DIABETES].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Dexamethasone; Diabetes Mellitus; Diet; Diet Therapy; Gou | 1963 |
[INTOLERANCE PHENOMENA IN ISONIAZID USE].
Topics: Diabetes Mellitus; Diarrhea; Drug Hypersensitivity; Isoniazid; Toxicology; Tuberculosis; Tuberculosi | 1963 |
[TREATMENT OF THE TUBERCULOUS AND DIABETIC WITH CHLORPROPAMIDE].
Topics: Chlorpropamide; Diabetes Mellitus; Geriatrics; Isoniazid; Streptomycin; Toxicology; Tuberculosis; Tu | 1964 |
[TREATMENT OF TUBERCULOSIS AND DIABETES BECOMING SIMILAR].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Cycloserine; Diabetes Mellitus; Ethionamide; Isoniazid; P | 1964 |
[ASSOCIATION OF PULMONARY TUBERCULOSIS AND DIABETES MELLITUS].
Topics: Diabetes Mellitus; Humans; Hypoglycemic Agents; Insulin; Insulin, Long-Acting; Isoniazid; Kanamycin; | 1964 |
[APROPOS OF ETHIONAMIDE JAUNDICE].
Topics: Alanine Transaminase; Alcoholism; Aminosalicylic Acid; Aminosalicylic Acids; Aspartate Aminotransfer | 1964 |
[CHEMO-ANTIBIOTIC THERAPY OF TUBERCULOSIS IN DIABETICS AND ITS REPERCUSSIONS ON GLUCIDE METABOLISM].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Blood Glucose; Carbohydrate Metabo | 1964 |
CONJOINT CLINIC ON DRUGS AND GENES.
Topics: Acetates; Aminosalicylic Acid; Aminosalicylic Acids; Coenzyme A; Diabetes Mellitus; Genetics, Medica | 1965 |
[TRYPTOPHAN STRESS AND INH METABOLISM IN THE TUBERCULOSIS DIABETIC].
Topics: Diabetes Mellitus; Drug Therapy; Humans; Isoniazid; Mental Disorders; Toxicology; Tryptophan; Tuberc | 1964 |
[Therapy of diabetes mellitus with isoniazid].
Topics: Diabetes Mellitus; Isomerism; Isoniazid; Niacin; Nicotinic Acids | 1954 |
[The effectiveness of pyrazinamide-containing six-month short course chemotherapy].
Topics: Adult; Aged; Aged, 80 and over; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Diabe | 2000 |
[Behavioral disorders after treatment with isoniazid].
Topics: Aging; Alcoholism; Antitubercular Agents; Behavior; Contraindications; Diabetes Mellitus; Female; Hu | 2001 |
Tuberculosis after corticosteroid therapy.
Topics: Adrenal Cortex Hormones; Adult; Aged; Airway Obstruction; Arthritis, Rheumatoid; Dermatitis, Exfolia | 1976 |
[Urinary xanthurenic acid levels].
Topics: Age Factors; Aged; Alcoholism; Arthritis, Rheumatoid; Child; Contraceptives, Oral; Diabetes Mellitus | 1978 |
[Pulmonary tuberculosis as a complication of diabetes based on clinical material between 1947 and 1970].
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Child; Diabetes Complications; Diabetes Mellitus; Hum | 1971 |
[Level of isoniazid labeled with C-14 in the tissue of animals infected with tuberculosis administered insulin].
Topics: Animals; Carbon Isotopes; Diabetes Mellitus; Female; Guinea Pigs; Insulin; Isoniazid; Male; Tubercul | 1969 |
The rate of isoniazid inactivation in Finnish diabetic and non-diabetic patients.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; F | 1967 |