isoniazid has been researched along with Diabetes Mellitus, Type 2 in 15 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin (MET) is a potential combination drug to elevate anti-TB efficacy." | 5.51 | Metformin induced autophagy in diabetes mellitus - Tuberculosis co-infection patients: A case study. ( Ali, M; Mertaniasih, NM; Novita, BD; Pranoto, A; Soediono, EI, 2019) |
| "To observe the clinical effect on type 2 diabetes mellitus (T2DM) complicated with pulmonary tuberculosis (TB) of insulin, isoniazid, rifampicin, pyrazinamide and ethambutol (conventional medication) administered together with Qi-boosting and Yin-nourishing decoction derived from Traditional Chinese Medicine (TCM)." | 2.80 | Effects on type 2 diabetes complicated with pulmonary tuberculosis: regiment of insulin, isoniazid, rifampicin, pyrazinamide and ethambutol versus the regiment plus Qi-boosting and Yin-nourishing decoction of Traditional Chinese Medicine. ( Shi, G; Zhang, L, 2015) |
| "Metformin (MET) is a potential combination drug to elevate anti-TB efficacy." | 1.51 | Metformin induced autophagy in diabetes mellitus - Tuberculosis co-infection patients: A case study. ( Ali, M; Mertaniasih, NM; Novita, BD; Pranoto, A; Soediono, EI, 2019) |
| " In this article, a case series is presented to illustrate the value of individualized TB drug dosing in four patients with low TB drug concentrations." | 1.38 | Therapeutic drug monitoring in the treatment of tuberculosis patients. ( Aarnoutse, R; Boeree, M; Ijdema, D; Magis-Escurra, C; van den Boogaard, J, 2012) |
| "Isoniazid inactivation was studied in 60 patients with concomitant diseases (pulmonary tuberculosis and diabetes mellitus)." | 1.31 | [Features of isoniazid activation in patients with tuberculosis and diabetes mellitus]. ( Chernykh, NA; Kaminskaia, GO; Karachunskiĭ, MA; Kossiĭ, IuE, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ntinginya, NE | 1 |
| Te Brake, L | 1 |
| Sabi, I | 1 |
| Chamba, N | 1 |
| Kilonzo, K | 1 |
| Laizer, S | 1 |
| Andia-Biraro, I | 1 |
| Kibirige, D | 1 |
| Kyazze, AP | 1 |
| Ninsiima, S | 1 |
| Critchley, JA | 1 |
| Romeo, R | 1 |
| van de Maat, J | 1 |
| Olomi, W | 1 |
| Mrema, L | 1 |
| Magombola, D | 1 |
| Mwayula, IH | 1 |
| Sharples, K | 1 |
| Hill, PC | 1 |
| van Crevel, R | 1 |
| Lyu, M | 1 |
| Wang, D | 1 |
| Zhao, J | 1 |
| Yang, Z | 1 |
| Chong, W | 1 |
| Zhao, Z | 1 |
| Ming, L | 1 |
| Ying, B | 1 |
| Novita, BD | 1 |
| Ali, M | 1 |
| Pranoto, A | 1 |
| Soediono, EI | 1 |
| Mertaniasih, NM | 1 |
| Boglou, P | 1 |
| Steiropoulos, P | 1 |
| Papanas, N | 1 |
| Bouros, D | 1 |
| Babalik, A | 1 |
| Ulus, IH | 1 |
| Bakirci, N | 1 |
| Kuyucu, T | 1 |
| Arpag, H | 1 |
| Dagyildizi, L | 1 |
| Capaner, E | 1 |
| Shi, G | 1 |
| Zhang, L | 1 |
| Satti, L | 1 |
| Abbasi, S | 1 |
| Sattar, A | 1 |
| Ikram, A | 1 |
| Manzar, MA | 1 |
| Khalid, MM | 1 |
| Magis-Escurra, C | 1 |
| van den Boogaard, J | 1 |
| Ijdema, D | 1 |
| Boeree, M | 1 |
| Aarnoutse, R | 1 |
| Hsu, AH | 1 |
| Lee, JJ | 1 |
| Chiang, CY | 1 |
| Li, YH | 1 |
| Chen, LK | 1 |
| Lin, CB | 1 |
| Chernykh, NA | 2 |
| Karachunskiĭ, MA | 2 |
| Kaminskaia, GO | 2 |
| Kossiĭ, IuE | 2 |
| Kihara, Y | 1 |
| Otsuki, M | 1 |
| Hernández García, P | 1 |
| Martínez Cruz, F | 1 |
| Cayuelas Martínez, T | 1 |
| Miarka, J | 1 |
| Jonderko, G | 1 |
| Straszecka, J | 1 |
| Lachowicz, B | 1 |
| Jimenez-Lucho, VE | 1 |
| del Busto, R | 1 |
| Odel, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double Blind Placebo Controlled Trial of Rifapentine and Isoniazid for Prevention of Tuberculosis in People With Diabetes[NCT04600167] | Phase 3 | 3,000 participants (Anticipated) | Interventional | 2022-06-17 | Recruiting | ||
| Efficacy of Metformin for Sputum Conversion in Patients With Active Pulmonary Tuberculosis: A Randomized Controlled Trial[NCT05215990] | Phase 1/Phase 2 | 80 participants (Anticipated) | Interventional | 2022-01-15 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for isoniazid and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
A novel risk factor for predicting anti-tuberculosis drug resistance in patients with tuberculosis complicated with type 2 diabetes mellitus.
Topics: Adult; Aged; Antitubercular Agents; Diabetes Mellitus, Type 2; Drug Resistance, Bacterial; Drug Resi | 2020 |
2 trials available for isoniazid and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Rifapentine and isoniazid for prevention of tuberculosis in people with diabetes (PROTID): protocol for a randomised controlled trial.
Topics: Adult; Antitubercular Agents; Cohort Studies; Diabetes Mellitus, Type 2; HIV Infections; Humans; Iso | 2022 |
Effects on type 2 diabetes complicated with pulmonary tuberculosis: regiment of insulin, isoniazid, rifampicin, pyrazinamide and ethambutol versus the regiment plus Qi-boosting and Yin-nourishing decoction of Traditional Chinese Medicine.
Topics: Adult; Aged; Antitubercular Agents; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Drugs, Chi | 2015 |
12 other studies available for isoniazid and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Metformin induced autophagy in diabetes mellitus - Tuberculosis co-infection patients: A case study.
Topics: Adult; Antitubercular Agents; Autophagy; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Etham | 2019 |
Hypoglycaemia due to interaction of glimepiride with isoniazid in a patient with type 2 diabetes mellitus.
Topics: Aged; Antitubercular Agents; Diabetes Mellitus, Type 2; Drug Interactions; Female; Humans; Hypoglyce | 2013 |
Plasma concentrations of isoniazid and rifampin are decreased in adult pulmonary tuberculosis patients with diabetes mellitus.
Topics: Adult; Antitubercular Agents; Biological Availability; Diabetes Mellitus, Type 2; Drug Administratio | 2013 |
Bone marrow infection with Mycobacterium fortuitum in a diabetic patient.
Topics: Amikacin; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bone Marrow; Bone Marrow Diseases; Cip | 2011 |
Therapeutic drug monitoring in the treatment of tuberculosis patients.
Topics: Adult; Aged; Alcoholism; Antibiotics, Antitubercular; Antitubercular Agents; Chromatography, High Pr | 2012 |
Diabetes is associated with drug-resistant tuberculosis in Eastern Taiwan.
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Child, Preschool; Cross-Sectional Studies; Di | 2013 |
[Effectiveness of an intensive chemotherapy stage in new cases of pulmonary tuberculosis and diabetes mellitus].
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Data Interpretation, Statistical; Diabetes Melli | 2004 |
Interaction of gliclazide and rifampicin.
Topics: Aged; Antibiotics, Antitubercular; Clarithromycin; Diabetes Mellitus, Type 2; Drug Interactions; Dru | 2000 |
[Features of isoniazid activation in patients with tuberculosis and diabetes mellitus].
Topics: Antitubercular Agents; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Isoniazid; Tube | 2001 |
[PPD and chemoprophylaxis in diabetes mellitus].
Topics: Adult; Aged; Aged, 80 and over; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetes Mellitus | 1992 |
[Acetylation phenotype as a risk factor of diabetic neuropathy].
Topics: Acetylation; Acetyltransferases; Adult; Aged; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 1990 |
Isoniazid and ethambutol as a cause of optic neuropathy.
Topics: Aged; Diabetes Mellitus, Type 2; Drug Synergism; Ethambutol; Humans; Isoniazid; Male; Mycobacterium | 1987 |