isoniazid has been researched along with Coma in 33 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acute isoniazid intoxication is characterized by a clinical triad consisting of metabolic acidosis resistant to treatment with sodium bicarbonate, seizures which may be fatal and refractory to standard anticonvulsant therapy, and coma." | 7.73 | Seizures, metabolic acidosis and coma resulting from acute isoniazid intoxication. ( Ekici, NZ; Kefi, A; Sakarya, M; Topcu, I; Yentur, EA, 2005) |
| "Overingestion of isoniazid can cause confusion, slurred speech, seizures, coma, and death." | 7.69 | Coma from long-term overingestion of isoniazid. ( Hewitt, CC; Salkind, AR, 1997) |
| "Pyridoxine has been reported to be effective in treating isoniazid-induced seizures." | 5.28 | Reversal of prolonged isoniazid-induced coma by pyridoxine. ( Brent, J; Kulig, K; Rumack, BH; Vo, N, 1990) |
| " Acute isoniazid intoxication is characterized by a clinical triad consisting of metabolic acidosis resistant to treatment with sodium bicarbonate, seizures which may be fatal and refractory to standard anticonvulsant therapy, and coma." | 3.73 | Seizures, metabolic acidosis and coma resulting from acute isoniazid intoxication. ( Ekici, NZ; Kefi, A; Sakarya, M; Topcu, I; Yentur, EA, 2005) |
| "A 14-yr old previously healthy girl receiving preventive isoniazid therapy who suddenly developed generalized tonic-clonic seizures and coma." | 3.70 | Acute isoniazid neurotoxicity during preventive therapy. ( Gorjup, V; Horvat, M; Martinjak-Dvorsek, I; Noc, M, 2000) |
| "Overingestion of isoniazid can cause confusion, slurred speech, seizures, coma, and death." | 3.69 | Coma from long-term overingestion of isoniazid. ( Hewitt, CC; Salkind, AR, 1997) |
| "Acute isoniazid intoxication is characterised by high mortality and vomiting, seizures, coma and metabolic acidosis as main symptoms." | 3.67 | [Acute isoniazid poisoning]. ( Bode, U; Köster, B; Musch, E; Weber, HP, 1985) |
| "Seizures are commonly encountered in patients who do not have epilepsy." | 2.40 | Medical causes of seizures. ( Delanty, N; French, JA; Vaughan, CJ, 1998) |
| "Pyridoxine has been reported to be effective in treating isoniazid-induced seizures." | 1.28 | Reversal of prolonged isoniazid-induced coma by pyridoxine. ( Brent, J; Kulig, K; Rumack, BH; Vo, N, 1990) |
| "One patient presented with oliguria and coma whereas seizures were the dominant feature in the second case." | 1.27 | Acute isoniazid toxicity--report of 2 cases and review of literature. ( Gilhotra, R; Malik, SK; Sharma, BK; Singh, S, 1987) |
| "We treated five isoniazid-overdosed patients each with a single dose of pyridoxine hydrochloride equivalent to the gram amount of isoniazid ingested and compared their outcome with that of 41 patients from the literature who received little or no pyridoxine." | 1.26 | Single high-dose pyridoxine treatment for isoniazid overdose. ( Lacouture, PG; Lovejoy, FH; Wason, S, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (66.67) | 18.7374 |
| 1990's | 7 (21.21) | 18.2507 |
| 2000's | 3 (9.09) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uzman, S | 1 |
| Uludağ Yanaral, T | 1 |
| Toptaş, M | 1 |
| Koç, A | 1 |
| Taş, A | 1 |
| Bican, G | 1 |
| Tai, WP | 1 |
| Yue, H | 1 |
| Hu, PJ | 1 |
| MEREU, T | 1 |
| MORETTI, M | 1 |
| LEMERCIER, JP | 1 |
| DORDAIN, M | 1 |
| RAPIN, M | 1 |
| AMSTUTZ, P | 1 |
| GORCE, F | 1 |
| BAROIS, A | 1 |
| GOULON, M | 1 |
| Topcu, I | 1 |
| Yentur, EA | 1 |
| Kefi, A | 1 |
| Ekici, NZ | 1 |
| Sakarya, M | 1 |
| Youssef, W | 1 |
| Cahuana, A | 1 |
| Feijoo, B | 1 |
| Pou, J | 1 |
| Miller, J | 1 |
| Robinson, A | 1 |
| Percy, AK | 1 |
| Wason, S | 1 |
| Lacouture, PG | 1 |
| Lovejoy, FH | 1 |
| Lahori, UC | 1 |
| Sharma, DB | 1 |
| Marcovigi, P | 1 |
| Valtancoli, E | 1 |
| Calbi, P | 1 |
| Farolfi, P | 1 |
| Calbi, G | 1 |
| Chang, YD | 1 |
| Yang, CC | 1 |
| Lin, TJ | 1 |
| Ger, J | 1 |
| Deng, JF | 1 |
| Salkind, AR | 1 |
| Hewitt, CC | 1 |
| Delanty, N | 1 |
| Vaughan, CJ | 1 |
| French, JA | 1 |
| Temmerman, W | 1 |
| Dhondt, A | 1 |
| Vandewoude, K | 1 |
| Martinjak-Dvorsek, I | 1 |
| Gorjup, V | 1 |
| Horvat, M | 1 |
| Noc, M | 1 |
| Malizia, E | 1 |
| Adreucci, G | 1 |
| Signore, L | 1 |
| Colombo, G | 1 |
| Sievers, ML | 1 |
| Herrier, RN | 1 |
| Bogusz, M | 1 |
| de' Clari, F | 1 |
| Brent, J | 1 |
| Vo, N | 1 |
| Kulig, K | 1 |
| Rumack, BH | 1 |
| Orlowski, JP | 1 |
| Paganini, EP | 1 |
| Pippenger, CE | 1 |
| Gilhotra, R | 1 |
| Malik, SK | 1 |
| Singh, S | 1 |
| Sharma, BK | 1 |
| Köster, B | 1 |
| Bode, U | 1 |
| Weber, HP | 1 |
| Musch, E | 1 |
| Bleandonu, G | 2 |
| Boye, J | 2 |
| Mellerio, F | 2 |
| Gaultier, M | 1 |
| Fournier, E | 1 |
| Gervais, P | 1 |
| Frejaville, JP | 1 |
| Luzhnikov, EA | 1 |
| Shimanko, II | 1 |
| Aleksandrovskiĭ, VN | 1 |
| Friedman, SA | 1 |
| Dimitriu, CG | 1 |
| Klein, S | 1 |
| Cartier, F | 1 |
| Curtes, JP | 1 |
2 reviews available for isoniazid and Coma
| Article | Year |
|---|---|
Medical causes of seizures.
Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Blood Pressure; Brain Diseases; Broncho | 1998 |
Acute isoniazid intoxication: seizures, acidosis and coma.
Topics: Acidosis; Acute Disease; Adolescent; Antitubercular Agents; Coma; Diagnosis, Differential; Drug Over | 1999 |
31 other studies available for isoniazid and Coma
| Article | Year |
|---|---|
Acute isoniazid intoxication: an uncommon cause of convulsion, coma and acidosis.
Topics: Acidosis; Antitubercular Agents; Coma; Humans; Infusions, Intravenous; Isoniazid; Male; Pyridoxine; | 2013 |
Coma caused by isoniazid poisoning in a patient treated with pyridoxine and hemodialysis.
Topics: Adult; Antitubercular Agents; Coma; Humans; Isoniazid; Male; Pyridoxine; Renal Dialysis; Suicide, At | 2008 |
[Loss of consciousness with relapse during treatment with Rimifon].
Topics: Child; Chronic Disease; Coma; Consciousness; Humans; Infant; Isoniazid; Recurrence; Tuberculosis; Tu | 1961 |
[ACUTE ISONIAZID POISONING WITH PERMANENT CEREBRAL DAMAGE].
Topics: Atrophy; Brain Damage, Chronic; Cerebral Cortex; Child; Coma; Exchange Transfusion, Whole Blood; Int | 1963 |
[ACUTE INTOXICATION BY ISONIAZID].
Topics: Acidosis; Bicarbonates; Blood Gas Analysis; Coma; Drug-Related Side Effects and Adverse Reactions; H | 1963 |
[ANURIA CAUSED BY ACUTE INTERSTITIAL NEPHROPATHY IN THE COURSE OF PROLONGED PHENINDIONE TREATMENT].
Topics: Anuria; Chloramphenicol; Coma; Coumarins; Dermatitis; Diagnosis; Dialysis; Eosinophils; Erythromycin | 1964 |
Seizures, metabolic acidosis and coma resulting from acute isoniazid intoxication.
Topics: Acidosis; Acute Disease; Adolescent; Anticonvulsants; Antitubercular Agents; Charcoal; Child; Coma; | 2005 |
[Acute isoniazid poisoning].
Topics: Acidosis; Child; Coma; Female; Humans; Isoniazid; Seizures | 1983 |
Acute isoniazid poisoning in childhood.
Topics: Adolescent; Child, Preschool; Coma; Female; Humans; Infant; Isoniazid; Male; Paraldehyde; Pyridoxine | 1980 |
Single high-dose pyridoxine treatment for isoniazid overdose.
Topics: Acidosis; Adolescent; Adult; Bicarbonates; Coma; Female; Humans; Isoniazid; Male; Pyridoxine; Seizur | 1981 |
Acute isoniazid poisoning in children.
Topics: Acute Disease; Child, Preschool; Coma; Diazepam; Female; Humans; Isoniazid; Pyridoxine; Seizures | 1981 |
[Pyridoxine administration in acute isoniazid intoxication].
Topics: Acidosis; Blood Gas Analysis; Child, Preschool; Coma; Female; Gastric Lavage; Humans; Isoniazid; Poi | 1993 |
Acute isoniazid intoxication: a case report.
Topics: Acidosis; Acute Disease; Adult; Antitubercular Agents; Coma; Female; Humans; Isoniazid; Seizures | 1996 |
Coma from long-term overingestion of isoniazid.
Topics: Antitubercular Agents; Coma; Drug Overdose; Humans; Isoniazid; Male; Middle Aged | 1997 |
Acute isoniazid neurotoxicity during preventive therapy.
Topics: Acute Disease; Adolescent; Antitubercular Agents; Coma; Conscious Sedation; Electroencephalography; | 2000 |
[Toxic coma due to drugs].
Topics: Acetylcholine; Amphetamine; Barbiturates; Codeine; Coma; Ephedrine; Epinephrine; Humans; Isoniazid; | 1976 |
Treatment of acute isoniazid toxicity.
Topics: Acidosis; Adolescent; Adult; Airway Obstruction; Anticonvulsants; Bicarbonates; Coma; Diuresis; Fema | 1975 |
The usefulness of the enzymatic tests in acute poisonings.
Topics: Adolescent; Adult; Aged; Alcohol Oxidoreductases; Alcoholic Intoxication; Alkaline Phosphatase; Aspi | 1975 |
The paradoxical anticonvulsive and awakening effect of high-dose pyridoxine treatment for isoniazid intoxication.
Topics: Coma; Humans; Isoniazid; Pyridoxine | 1992 |
Reversal of prolonged isoniazid-induced coma by pyridoxine.
Topics: Adolescent; Adult; Coma; Drug Overdose; Female; Humans; Isoniazid; Male; Pyridoxine | 1990 |
Treatment of a potentially lethal dose isoniazid ingestion.
Topics: Acidosis; Blood Gas Analysis; Child; Coma; Emergencies; Humans; Isoniazid; Male; Oliguria; Renal Dia | 1988 |
Acute isoniazid toxicity--report of 2 cases and review of literature.
Topics: Acute Disease; Adult; Coma; Humans; Isoniazid; Male; Seizures; Suicide | 1987 |
[Acute isoniazid poisoning].
Topics: Acidosis; Coma; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Isoniazid; Metab | 1985 |
[Neuropsychiatric incidences in antitubercular treatment consisting of isoniazid or isoniazid and ethionamide (8 cases)].
Topics: Acidosis; Adult; Alcoholism; Ammonia; Avitaminosis; Carboxy-Lyases; Chromatography, Paper; Chromatog | 1969 |
Contribution of electroencephalography to resuscitation in toxicology.
Topics: Amitriptyline; Barbiturates; Carbon Monoxide Poisoning; Coma; Electroencephalography; Fungi; Humans; | 1973 |
[Differential diagnosis and emergency treatment of comatose states in acute poisoning].
Topics: Adult; Alcoholic Intoxication; Antidotes; Barbiturates; Coma; Diagnosis, Differential; First Aid; Hu | 1972 |
Death following massive ingestion of isoniazid.
Topics: Acidosis; Adolescent; Anticonvulsants; Coma; Fever; Gastric Lavage; Humans; Intubation, Intratrachea | 1969 |
[Neuropsychiatric repercussions of antitubercular treatment with isoniazid, or isoniazid and ethionamide (apropos of 8 cases)].
Topics: Adult; Coma; Ethionamide; Female; Humans; Isoniazid; Male; Mental Disorders; Middle Aged; Neurologic | 1969 |
[Acute poisonings and convulsive crises. Electroencephalographic study of 3 very different products: Rimifon, chloralose, metaldehyde].
Topics: Acetaldehyde; Brain; Chloralose; Coma; Electroencephalography; Humans; Isoniazid; Poisoning; Seizure | 1967 |
[Acute isoniazid poisoning. (Preliminary note on the study of 231 cases with poisoning)].
Topics: Adolescent; Adult; Amnesia; Coma; Female; Gastrointestinal Diseases; Hallucinations; Humans; Hypergl | 1968 |
[Convulsive crises and coma revealing acute isoniazid poisoning].
Topics: Adult; Coma; Female; Humans; Isoniazid; Seizures; Tuberculosis, Pulmonary | 1968 |