isoniazid has been researched along with Child Malnutrition in 3 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Child Malnutrition: Malnutrition occurring in children ages 2 to 12 years, which is due to insufficient intake of food, dietary nutrients, or a pathophysiologic condition which prevents the absorption and utilization of food. Growth and development are markedly affected.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The serum INH concentrations were higher in the undernourished group but the pharmacokinetic parameters were comparable with those in the normal nutrition group." | 6.75 | Pharmacokinetics of isoniazid in moderately malnourished children with tuberculosis. ( Gupta, D; Gupta, P; Mishra, TK; Roy, V; Sethi, GR, 2010) |
| " We estimated tuberculosis treatment outcomes in children younger than 5 years following WHO guidelines (children are dosed by weight bands corresponding to the number of fixed-dose combination tablets [75 mg rifampicin, 50 mg isoniazid, 150 mg pyrazinamide]) and two alternative dosing strategies: one based on a proposed algorithm that uses age, weight, and available formulations, in which underweight children would receive the same drug doses as would normal weight children of the same age; and another based on an individualised algorithm without dose limitations, in which derived doses results in target exposure attainment for the typical child." | 3.91 | Alternative dosing guidelines to improve outcomes in childhood tuberculosis: a mathematical modelling study. ( Dodd, PJ; Dooley, KE; Garcia-Prats, AJ; Hesseling, AC; McKenna, L; Radtke, KK; Savic, RM, 2019) |
| " The serum INH concentrations were higher in the undernourished group but the pharmacokinetic parameters were comparable with those in the normal nutrition group." | 2.75 | Pharmacokinetics of isoniazid in moderately malnourished children with tuberculosis. ( Gupta, D; Gupta, P; Mishra, TK; Roy, V; Sethi, GR, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Radtke, KK | 1 |
| Dooley, KE | 1 |
| Dodd, PJ | 1 |
| Garcia-Prats, AJ | 1 |
| McKenna, L | 1 |
| Hesseling, AC | 1 |
| Savic, RM | 1 |
| Roy, V | 1 |
| Gupta, D | 1 |
| Gupta, P | 1 |
| Sethi, GR | 1 |
| Mishra, TK | 1 |
| Donald, PR | 1 |
| Seifart, HI | 1 |
| Parkin, DP | 1 |
| van Jaarsveld, PP | 1 |
1 trial available for isoniazid and Child Malnutrition
| Article | Year |
|---|---|
Pharmacokinetics of isoniazid in moderately malnourished children with tuberculosis.
Topics: Antitubercular Agents; Child; Child Nutrition Disorders; Child, Preschool; Female; Humans; India; Is | 2010 |
2 other studies available for isoniazid and Child Malnutrition
| Article | Year |
|---|---|
Alternative dosing guidelines to improve outcomes in childhood tuberculosis: a mathematical modelling study.
Topics: Algorithms; Antitubercular Agents; Body Weight; Child Nutrition Disorders; Child, Preschool; Drug Ad | 2019 |
Hydrazine production in children receiving isoniazid for the treatment of tuberculous meningitis.
Topics: Child; Child Nutrition Disorders; Child, Preschool; Female; Half-Life; Hospitals, Teaching; Humans; | 1994 |