Page last updated: 2024-10-29

isoniazid and Cerebellar Ataxia

isoniazid has been researched along with Cerebellar Ataxia in 11 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)

Research Excerpts

ExcerptRelevanceReference
"Intracranial tuberculomas are rare yet lethal forms of tuberculosis."2.66Multiple tuberculomas in an immunocompetent patient and their diagnostic challenge in a high prevalence country: Case report and literature review. ( Alva-Diaz, C; Esteban-Arias, D; López-Saavedra, A; Metcalf, T; Orellana-Tovar, I; Pacheco-Barrios, K; Rodriguez-López, E; Velásquez-Rimachi, V, 2020)
" EFV is well known to cause neuropsychiatric side-effects on initiation, and a recent adult case series described late-onset neurotoxicity in the form of subacute ataxia and encephalopathy in patients treated with EFV for a median of 2 years, in association with toxic plasma levels of the drug."1.48A proposed management algorithm for late-onset efavirenz neurotoxicity. ( Asukile, MT; Chetty, S; Cross, HM; Hussey, HS; Lee Pan, EB; Tucker, LM, 2018)
"gamma-Aminobutyric acid (GABA) was measured in CSF as such and following acid hydrolysis by the ion-exchange/fluorometric method."1.27Free and conjugated GABA in human cerebrospinal fluid: effect of degenerative neurologic diseases and isoniazid. ( Manyam, BV; Tremblay, RD, 1984)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's6 (54.55)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Velásquez-Rimachi, V1
Orellana-Tovar, I1
Rodriguez-López, E1
López-Saavedra, A1
Esteban-Arias, D1
Pacheco-Barrios, K1
Metcalf, T1
Alva-Diaz, C1
Cross, HM1
Chetty, S1
Asukile, MT1
Hussey, HS1
Lee Pan, EB1
Tucker, LM1
Manyam, BV1
Tremblay, RD1
Kuriakose, P1
Dhar, KL1
Lewin, PK2
McGreal, D1
MacDonald, NE1
Bhardwaj, PK1
Bhardwaj, I1
Raman, PG1
Ganguly, K1
Avasthi, R1
Jain, AP1
Lampert, PW1
Schochet, SS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Neurological Aging Among People Living With HIV (SNAP)[NCT05678660]300 participants (Anticipated)Observational2022-07-06Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for isoniazid and Cerebellar Ataxia

ArticleYear
Multiple tuberculomas in an immunocompetent patient and their diagnostic challenge in a high prevalence country: Case report and literature review.
    The Indian journal of tuberculosis, 2020, Volume: 67, Issue:3

    Topics: Antitubercular Agents; Blindness; Brain; Brain Diseases; Cerebellar Ataxia; Dexamethasone; Drug Ther

2020

Other Studies

10 other studies available for isoniazid and Cerebellar Ataxia

ArticleYear
A proposed management algorithm for late-onset efavirenz neurotoxicity.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2018, Mar-28, Volume: 108, Issue:4

    Topics: Adult; Algorithms; Alkynes; Antitubercular Agents; Benzoxazines; Brain Diseases; Cerebellar Ataxia;

2018
Free and conjugated GABA in human cerebrospinal fluid: effect of degenerative neurologic diseases and isoniazid.
    Brain research, 1984, Jul-30, Volume: 307, Issue:1-2

    Topics: Adult; Age Factors; Aged; Cerebellar Ataxia; Dementia; Epilepsy; gamma-Aminobutyric Acid; Humans; Hu

1984
Isoniazid therapy in cerebellar ataxia.
    The Journal of the Association of Physicians of India, 1994, Volume: 42, Issue:11

    Topics: Adult; Cerebellar Ataxia; Humans; Isoniazid; Male; Respiratory Tract Infections

1994
Isoniazid toxicity with cerebellar ataxia in a child.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1993, Jan-01, Volume: 148, Issue:1

    Topics: Cerebellar Ataxia; Child; Female; Humans; Isoniazid; Poisoning; Pyridoxine

1993
Isoniazid toxicity with cerebellar ataxia in a child.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1993, Apr-01, Volume: 148, Issue:7

    Topics: Cerebellar Ataxia; Child; Female; Humans; Isoniazid; Pyridoxine

1993
Isoniazid neurotoxicity.
    Pediatrics, 1996, Volume: 97, Issue:5

    Topics: Antitubercular Agents; Cerebellar Ataxia; Child; Dose-Response Relationship, Drug; Humans; Isoniazid

1996
Isoniazid in cerebellar ataxia.
    The Journal of the Association of Physicians of India, 1995, Volume: 43, Issue:9

    Topics: Cerebellar Ataxia; Child; Drug Therapy, Combination; Humans; Isoniazid; Male; Prednisolone

1995
Isoniazid therapy in cerebellar ataxia.
    The Journal of the Association of Physicians of India, 1995, Volume: 43, Issue:5

    Topics: 4-Aminobutyrate Transaminase; Cerebellar Ataxia; Dose-Response Relationship, Drug; GABA Agonists; Hu

1995
Phenytoin--isoniazid interaction.
    The Journal of the Association of Physicians of India, 1989, Volume: 37, Issue:11

    Topics: Adult; Cerebellar Ataxia; Drug Synergism; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans;

1989
Electron microscopic observations on experimental spongy degeneration of the cerebellar white matter.
    Journal of neuropathology and experimental neurology, 1968, Volume: 27, Issue:2

    Topics: Animals; Axons; Brain Stem; Cerebellar Ataxia; Cerebellum; Demyelinating Diseases; Ducks; Encephalom

1968