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isoniazid and Central Nervous System Disease

isoniazid has been researched along with Central Nervous System Disease in 17 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Research Excerpts

ExcerptRelevanceReference
"Efavirenz (EFV) and rifampicin-isoniazid (RH) are cornerstone drugs in human immunodeficiency virus (HIV)-tuberculosis (TB) coinfection treatment but with complex drug interactions, efficacy and safety challenges."4.98Pharmacokinetics of efavirenz in patients on antituberculosis treatment in high human immunodeficiency virus and tuberculosis burden countries: A systematic review. ( Atwine, D; Bonnet, M; Taburet, AM, 2018)
" Serum isoniazid level was in the toxic range, the result of a dispensing error as well as a possible pharmacogenetic factor."1.35Neuroimaging findings in isoniazid central nervous system toxicity, presumed intramyelinic edema. ( Bitnun, A; Blaser, S; Cohen, E; Fluss, J; Hawkes, M; Kitai, I; Tran, D, 2008)
"To study the frequency and degree of adverse effect, other than liver dysfunction, of isoniazid (INH) preventive therapy in Japanese people."1.34[Adverse effect other than liver dysfunction in treatment of latent tuberculous infection by isoniazid]. ( Hoshino, H; Ito, K; Kato, S; Masuyama, H; Nakazono, T; Sugita, H; Yoshiyama, T, 2007)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's0 (0.00)18.2507
2000's3 (17.65)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atwine, D1
Bonnet, M1
Taburet, AM1
Hasiloglu, ZI1
Albayram, S1
Asik, M1
Kilic, O1
Unver, O1
Erdemli, HE1
Kocer, N1
CAFARO, C1
UTKIN, VV1
Ito, K1
Hoshino, H1
Nakazono, T1
Masuyama, H1
Sugita, H1
Yoshiyama, T1
Kato, S1
Hori, S1
Hawkes, M1
Kitai, I1
Blaser, S1
Cohen, E1
Bitnun, A1
Fluss, J1
Tran, D1
Brown, A1
Mallett, M1
Fiser, D1
Arnold, WC1
Addington, WW1
Adornato, B1
Lampert, P1
Seidell, MA1
Wasik, A1
Rajtar-Leontiew, Z1
Spens, N1
Tattersall, WH1
Hughes, WT1
Nauwald, G1

Reviews

3 reviews available for isoniazid and Central Nervous System Disease

ArticleYear
Pharmacokinetics of efavirenz in patients on antituberculosis treatment in high human immunodeficiency virus and tuberculosis burden countries: A systematic review.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:8

    Topics: Africa; Anti-HIV Agents; Antitubercular Agents; Asia; Body Weight; Central Nervous System Diseases;

2018
[Adverse effects and safety of antimicrobial agents-neurotoxicities].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Feb-28, Volume: 65 Suppl 2 Pt. 1

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; beta-Lactams; Central Nervous System Diseases; Drug

2007
Status spongiosus of nervous tissue. Electron microscopic studies.
    Acta neuropathologica, 1971, Volume: 19, Issue:4

    Topics: Adult; Animals; Axons; Brain; Brain Edema; Central Nervous System Diseases; Cerebral Cortex; Cytopla

1971

Trials

1 trial available for isoniazid and Central Nervous System Disease

ArticleYear
A five-year assessment of controlled trials of in-patient and out-patient treatment and of plaster-of-Paris jackets for tuberculosis of the spine in children on standard chemotherapy. Studies in Masan and Pusan, Korea. Fifth report of the Medical Research
    The Journal of bone and joint surgery. British volume, 1976, Volume: 58-B, Issue:4

    Topics: Abscess; Adolescent; Ambulatory Care; Aminosalicylic Acid; Antitubercular Agents; Bed Rest; Casts, S

1976

Other Studies

13 other studies available for isoniazid and Central Nervous System Disease

ArticleYear
MRI findings of isoniazid-induced central nervous system toxicity in a child.
    Clinical radiology, 2012, Volume: 67, Issue:9

    Topics: Antitubercular Agents; Brain; Central Nervous System; Central Nervous System Diseases; Child; Diffus

2012
[ALTERATIONS OF THE CENTRAL NERVOUS SYSTEM IN ACUTE LEUKEMIAS].
    Il Policlinico. Sezione pratica, 1964, Apr-20, Volume: 71

    Topics: Adolescent; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Blood Transfu

1964
[TOXIC EFFECT OF CYCLOSERINE].
    Problemy tuberkuleza, 1963, Volume: 41

    Topics: Alanine Transaminase; Aminosalicylic Acid; Aminosalicylic Acids; Aspartate Aminotransferases; Centra

1963
[Adverse effect other than liver dysfunction in treatment of latent tuberculous infection by isoniazid].
    Kekkaku : [Tuberculosis], 2007, Volume: 82, Issue:1

    Topics: Adolescent; Adult; Antitubercular Agents; Central Nervous System Diseases; Chemical and Drug Induced

2007
Neuroimaging findings in isoniazid central nervous system toxicity, presumed intramyelinic edema.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2008, Volume: 12, Issue:6

    Topics: Antitubercular Agents; Blood Cell Count; Brain Edema; Central Nervous System Diseases; Child, Presch

2008
Acute isoniazid intoxication: reversal of CNS symptoms with large doses of pyridoxine.
    Pediatric pharmacology (New York, N.Y.), 1984, Volume: 4, Issue:3

    Topics: Adolescent; Central Nervous System Diseases; Humans; Isoniazid; Male; Pyridoxine

1984
The side effects and interactions of antituberculosis drugs.
    Chest, 1979, Volume: 76, Issue:6 Suppl

    Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Central Nervous System Diseases; Chemical and Dru

1979
Isoniazid induced life-threatening neurologic reaction in an allergic individual.
    Annals of allergy, 1970, Volume: 28, Issue:6

    Topics: Adult; Anaphylaxis; Asthma; Bronchitis; Central Nervous System Diseases; Chemical and Drug Induced L

1970
Mental disorders caused by isonicotinic acid hydrazide (INH) in the course of treatment of pulmonary tuberculosis.
    Polish medical journal, 1970, Volume: 9, Issue:6

    Topics: Affective Symptoms; Age Factors; Alcoholism; Central Nervous System Diseases; Delirium; Delusions; E

1970
[Effect of isoniazid on pyridoxine (vitamin B6) metabolism in children. Experimental study].
    Annales de pediatrie, 1970, Feb-02, Volume: 17, Issue:2

    Topics: Acids; Animals; Central Nervous System Diseases; Child; Child, Preschool; Cycloserine; Drug Synergis

1970
Fungal infecton of central nervous system supervening during routine chemotherapy for pulmonary tuberculosis.
    British medical journal, 1965, Oct-09, Volume: 2, Issue:5466

    Topics: Aminosalicylic Acids; Aspergillosis; Brain Diseases; Central Nervous System Diseases; Humans; Isonia

1965
Generalized aspergillosis. A case involving the central nervous system.
    American journal of diseases of children (1960), 1966, Volume: 112, Issue:3

    Topics: Aspergillosis; Central Nervous System Diseases; Child; Chloramphenicol; Defense Mechanisms; Female;

1966
[Complications in the course of tuberculous spondylitis].
    Archiv fur orthopadische und Unfall-Chirurgie, 1966, Volume: 60, Issue:4

    Topics: Cardiovascular Diseases; Central Nervous System Diseases; Female; Gallbladder Diseases; Gastrointest

1966