Page last updated: 2024-10-29

isoniazid and Benign Neoplasms

isoniazid has been researched along with Benign Neoplasms in 77 studies

Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).

Research Excerpts

ExcerptRelevanceReference
"41 226 isoniazid exposed and 22 811 non-exposed patients admitted to Canadian institutions for the treatment of tuberculosis from 1952 to 1960 were followed to 1973 by computerised record linkage to the National Death Index and, for 1969 to 1973, to the National Cancer Incidence Reporting System; The mortality for the total cohort compared to that expected from the mortality in the Canadian population, was greater than expected for tuberculosis, other chest diseases and certain cancer sites associated with cigarette smoking (except bladder cancer)."7.66Isoniazid exposure in relation to cancer incidence and mortality in a cohort of tuberculosis patients. ( Coppock, E; Howe, GR; Lindsay, J; Miller, AB, 1979)
" The development of isoniazid for the prevention of tuberculosis is reviewed."3.68Prevention of infections in patients with neoplastic disease: use of a historical model for developmental strategies. ( White, MH, 1993)
"41 226 isoniazid exposed and 22 811 non-exposed patients admitted to Canadian institutions for the treatment of tuberculosis from 1952 to 1960 were followed to 1973 by computerised record linkage to the National Death Index and, for 1969 to 1973, to the National Cancer Incidence Reporting System; The mortality for the total cohort compared to that expected from the mortality in the Canadian population, was greater than expected for tuberculosis, other chest diseases and certain cancer sites associated with cigarette smoking (except bladder cancer)."3.66Isoniazid exposure in relation to cancer incidence and mortality in a cohort of tuberculosis patients. ( Coppock, E; Howe, GR; Lindsay, J; Miller, AB, 1979)
"Ever since the discovery of cancer stem cells (CSCs), they have progressively attracted more attention as a therapeutic target."3.01Extirpating the cancer stem cell hydra: Differentiation therapy and Hyperthermia therapy for targeting the cancer stem cell hierarchy. ( Saini, A; Sharma, D; Tewari, AB, 2023)
"No trend toward an increasing cancer rate in the isoniazid group was observed with the passage of time."2.65The incidence of cancer among participants in controlled, randomized isoniazid preventive therapy trial. ( Costello, HD; Snider, DE, 1980)
"However, how cancer patterns in humans compare to those of other species remains largely unknown."2.58From humans to hydra: patterns of cancer across the tree of life. ( Albuquerque, TAF; de Magalhães, JP; Doherty, A; Drummond do Val, L, 2018)
"The association of latent tuberculosis infection (LTBI) with subsequent cancer remains unclear."1.43Latent Tuberculosis Infection and the Risk of Subsequent Cancer. ( Chen, TJ; Chen, YM; Chou, KT; Chuang, PH; Feng, JY; Pan, SW; Su, VY; Su, WJ; Yen, YF, 2016)
"Infection in cancer patients with TB was significantly more often recorded among elderly patients and those suffering from poverty."1.38Characterization of Mycobacterium tuberculosis isolated from cancer patients with suspected tuberculosis infection in Egypt: identification, prevalence, risk factors and resistance pattern. ( Afifi, S; Eissa, S; El-Dahshan, R; El-Sharif, A; Rafeh, N, 2012)
"Suramin was used to analyze the growth-effects of blockade of iron uptake on two established human cell lines, U-937 (monocytoid) and K-562 (erythroleukemic)."1.27Role of iron in the proliferation of the established human tumor cell lines U-937 and K-562: effects of suramin and a lipophilic iron chelator (PIH). ( Bjelkenkrantz, K; Forsbeck, K; Nilsson, K, 1986)
"Thymidine deficiency has been reported to increase DNA replication errors and hence increase mutagenesis."1.27Theoretical involvement of vitamin B6 in tumour initiation. ( Prior, FG, 1985)
"National Cancer Institute and two Federal Agencies, seven drugs were listed."1.26Epidemiological studies of medically used drugs. ( Clemmesen, J; Hjalgrim-Jensen, S, 1980)
"Increased deaths from liver cirrhosis (5 vs 0."1.26Late effects following isoniazid therapy. ( Boice, JD; Fraumeni, JF, 1980)
"The mothers of children who developed cancer reported about 25% more illnesses during pregnancy than mothers of healthy control children."1.26Childhood cancer and drugs in pregnancy. ( Draper, GJ; Sanders, BM, 1979)
" The relative risks of death from all malignant neoplasms for patients receiving a total dosage of less than 50, 50-99, 100-199 and 200 g or more were 1."1.26An assessment of the carcinogenicity of isoniazid in patients with pulmonary tuberculosis. ( Fox, W; Peto, J; Stephens, R; Stott, H, 1976)

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-199058 (75.32)18.7374
1990's4 (5.19)18.2507
2000's1 (1.30)29.6817
2010's8 (10.39)24.3611
2020's6 (7.79)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Leitao, RCF2
Silva, F2
Ribeiro, GH2
Santos, IC2
Guerreiro, JF2
Mendes, F2
Batista, AA2
Pavan, FR2
da S Maia, PI2
Paulo, A2
Deflon, VM2
Belay, M1
Tulu, B1
Younis, S1
Jolliffe, DA1
Tayachew, D1
Manwandu, H1
Abozen, T1
Tirfie, EA1
Tegegn, M1
Zewude, A1
Forrest, S1
Mayito, J1
Huggett, JF1
Jones, GM1
O'Sullivan, DM1
Martineau, HM1
Noursadeghi, M1
Chandran, A1
Harris, KA1
Nikolayevskyy, V1
Demaret, J1
Berg, S1
Vordermeier, M1
Balcha, TT1
Aseffa, A1
Ameni, G1
Abebe, M1
Reece, ST1
Martineau, AR1
Mollan, KR1
Eron, JJ1
Krajewski, TJ1
Painter, W1
Duke, ER1
Morse, CG1
Goecker, EA1
Premkumar, L1
Wolfe, CR1
Szewczyk, LJ1
Alabanza, PL1
Loftis, AJ1
Degli-Angeli, EJ1
Brown, AJ1
Dragavon, JA1
Won, JJ1
Keys, J1
Hudgens, MG1
Fang, L1
Wohl, DA1
Cohen, MS1
Baric, RS1
Coombs, RW1
Sheahan, TP1
Fischer, WA1
Li, B1
Wang, X1
Hong, S1
Wang, Q1
Li, L1
Eltayeb, O1
Dong, C1
Shuang, S1
Liao, X1
Lu, J1
Ying, P1
Zhao, P1
Bai, Y1
Li, W1
Liu, M1
Moussa, RS1
Kovacevic, Z2
Richardson, DR5
Su, VY1
Yen, YF1
Pan, SW1
Chuang, PH1
Feng, JY1
Chou, KT1
Chen, YM1
Chen, TJ1
Su, WJ1
Yu, Y1
El-Sharif, A1
Afifi, S1
El-Dahshan, R1
Rafeh, N1
Eissa, S1
FORNI, PV1
LEIDER, M1
SAWICKY, HH1
BERENCSI, G1
ENTZ, A1
VAJKOCZY, A1
POMPE, K1
SKERIK, P1
WOLFART, W1
BALDINI, L2
BRAMBILLA, G2
WAGNER, H1
MORITZ, R1
JUHASZ, J2
BALO, J3
SZENDE, B2
MATSUDA, M2
SASA, M1
SUGIYAMA, K1
WALCZAK, H1
KENDREY, G1
COSSEL, L1
PELUSO, E1
TRENCSENI, T1
SZILVESZTROV, V1
GVALJA, I1
BIANCIFIORI, C1
BUCCIARELLI, E1
CLAYSON, DB2
SANTILLI, FE1
LOSCALZO, B1
MICHALOWSKI, R1
KUDEJKO, T1
HATTORI, S1
BONSER, GM2
ROE, FJ1
BOYLAND, E2
HADDOW, A1
Hammond, EC1
Selikoff, IJ1
Robitzek, EH1
Schmähl, D2
Habs, M1
Clemmesen, J2
Hjalgrim-Jensen, S2
Costello, HD1
Snider, DE2
Boice, JD1
Fraumeni, JF1
Sinués, B1
Rueda, P1
Benítez, J1
Saenz, MA1
Bernal, ML1
Lanuza, J1
Alda, O1
Tres, A1
Bartolome, M1
White, MH1
Milnes, K1
Glassroth, JL1
White, MC1
Sanders, BM1
Draper, GJ1
Howe, GR2
Lindsay, J1
Coppock, E1
Miller, AB1
Krauthammer, C1
Klerman, GL1
Stott, H1
Peto, J1
Stephens, R1
Fox, W1
Forsbeck, K1
Bjelkenkrantz, K1
Nilsson, K1
Anderson, TW1
Prior, FG1
Lesobre, R1
Ruffino, J1
Tubiana, M1
Thomas, PK1
Hildebrand, J1
Kenis, Y1
Miller, CT1
Sparks, FC1
Silverstein, MJ1
Hunt, JS1
Haskell, CM1
Pilch, YH1
Morton, DL1
Klastersky, J1
Weerts, D1
Hensgens, C1
Debusscher, L1
Ferebee, SH1
Munn, A1
Donaldson, RC1
Nyfors, A1
Cocchi, R1
Cocchi Belisario, C1
Rink, H1
Boutry, J1
Mistral, J1
Berlioz, L1
Klimovich, A3
Tökölyi, J1
Fontenille, L1
Ujvari, B1
Dujon, AM1
Giraudeau, M1
Thomas, F1
Adashek, JJ1
Subbiah, V1
Westphalen, CB1
Naing, A1
Kato, S1
Kurzrock, R1
Tewari, AB1
Saini, A1
Sharma, D1
Rathje, K1
Mortzfeld, B1
Hoeppner, MP1
Taubenheim, J1
Bosch, TCG1
Albuquerque, TAF1
Drummond do Val, L1
Doherty, A1
de Magalhães, JP1
Domazet-Lošo, T1
Anokhin, B1
Anton-Erxleben, F1
Hamm, MJ1
Lange, C1
Bosch, TC1
Shostak, S1

Reviews

10 reviews available for isoniazid and Benign Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Therapeutic potential of iron chelators in cancer therapy.
    Advances in experimental medicine and biology, 2002, Volume: 509

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Deferoxamine; Humans; Iron; Iron Chelating Agents; Isoni

2002
Analogues of pyridoxal isonicotinoyl hydrazone (PIH) as potential iron chelators for the treatment of neoplasia.
    Leukemia & lymphoma, 1998, Volume: 31, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cell Division; Humans; Iron

1998
Peripheral neuropathy.
    British medical journal, 1970, Feb-07, Volume: 1, Issue:5692

    Topics: Arsenic Poisoning; Deficiency Diseases; Humans; Isoniazid; Lead Poisoning; Metabolic Diseases; Neopl

1970
[Causal genesis of malignant tumors].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1973, Volume: 205, Issue:1

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Carcinogens; Carcinoma, Squamous Cell;

1973
The correlation of experimental carcinogenesis and cancer in man.
    Progress in experimental tumor research, 1969, Volume: 11

    Topics: Alkylating Agents; Animals; Anthelmintics; Carcinogens; Environmental Exposure; Griseofulvin; Humans

1969
Controlled chemoprophylaxis trials in tuberculosis. A general review.
    Bibliotheca tuberculosea, 1970, Volume: 26

    Topics: Adolescent; Adult; Age Factors; Alaska; Anemia; Child; Child, Preschool; Clinical Trials as Topic; D

1970
Cancer: slaying the nine-headed Hydra.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2023, Volume: 34, Issue:1

    Topics: Animals; Humans; Hydra; Medical Oncology; Neoplasms

2023
Extirpating the cancer stem cell hydra: Differentiation therapy and Hyperthermia therapy for targeting the cancer stem cell hierarchy.
    Clinical and experimental medicine, 2023, Volume: 23, Issue:7

    Topics: Animals; Cell Differentiation; Humans; Hydra; Hyperthermia, Induced; Neoplasms; Neoplastic Stem Cell

2023
From humans to hydra: patterns of cancer across the tree of life.
    Biological reviews of the Cambridge Philosophical Society, 2018, Volume: 93, Issue:3

    Topics: Animals; Biological Evolution; Genetic Predisposition to Disease; Humans; Hydra; Neoplasms; Species

2018

Trials

6 trials available for isoniazid and Benign Neoplasms

ArticleYear
The incidence of cancer among participants in controlled, randomized isoniazid preventive therapy trial.
    American journal of epidemiology, 1980, Volume: 111, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Female; Humans; Isoniazid; Male; Middle Ag

1980
Isoniazid--an attempt at retrospective prediction. A report of an ad hoc expert groups of the International Commission for Protection Against Environmental Mutagens and Carcinogens.
    Mutation research, 1980, Volume: 76, Issue:1

    Topics: Acetyltransferases; Biotransformation; Carcinogens; Chromosomes; Clinical Trials as Topic; Drug Eval

1980
An assessment of the possible association of isoniazid with human cancer deaths.
    The American review of respiratory disease, 1977, Volume: 116, Issue:6

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Isoniazid; Mal

1977
Isoniazid: epidemiological evidence.
    IARC scientific publications, 1985, Issue:65

    Topics: Adult; Child; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Ison

1985
[Isoniazid and carcinogenesis].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1969, Oct-26, Volume: 45, Issue:43

    Topics: Adenoma; Adult; Animals; Carbamates; Carcinoma; Child; Clinical Trials as Topic; Female; Humans; Hyd

1969
Controlled chemoprophylaxis trials in tuberculosis. A general review.
    Bibliotheca tuberculosea, 1970, Volume: 26

    Topics: Adolescent; Adult; Age Factors; Alaska; Anemia; Child; Child, Preschool; Clinical Trials as Topic; D

1970

Other Studies

62 other studies available for isoniazid and Benign Neoplasms

ArticleYear
Gallium and indium complexes with isoniazid-derived ligands: Interaction with biomolecules and biological activity against cancer cells and Mycobacterium tuberculosis.
    Journal of inorganic biochemistry, 2023, Volume: 240

    Topics: Antineoplastic Agents; Coordination Complexes; Gallium; Humans; Indium; Isoniazid; Ligands; Male; My

2023
Gallium and indium complexes with isoniazid-derived ligands: Interaction with biomolecules and biological activity against cancer cells and Mycobacterium tuberculosis.
    Journal of inorganic biochemistry, 2023, Volume: 240

    Topics: Antineoplastic Agents; Coordination Complexes; Gallium; Humans; Indium; Isoniazid; Ligands; Male; My

2023
Gallium and indium complexes with isoniazid-derived ligands: Interaction with biomolecules and biological activity against cancer cells and Mycobacterium tuberculosis.
    Journal of inorganic biochemistry, 2023, Volume: 240

    Topics: Antineoplastic Agents; Coordination Complexes; Gallium; Humans; Indium; Isoniazid; Ligands; Male; My

2023
Gallium and indium complexes with isoniazid-derived ligands: Interaction with biomolecules and biological activity against cancer cells and Mycobacterium tuberculosis.
    Journal of inorganic biochemistry, 2023, Volume: 240

    Topics: Antineoplastic Agents; Coordination Complexes; Gallium; Humans; Indium; Isoniazid; Ligands; Male; My

2023
    The Lancet. Microbe, 2021, Volume: 2, Issue:6

    Topics: Cross-Sectional Studies; DNA; Ethiopia; HeLa Cells; HIV Infections; Humans; Hydrogen Peroxide; Isoni

2021
DNA binding, antitumor activities, and hydroxyl radical scavenging properties of novel oxovanadium (IV) complexes with substituted isoniazid.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2013, Volume: 18, Issue:8

    Topics: 2,2'-Dipyridyl; Animals; Antineoplastic Agents; Apoptosis; Cattle; Cell Cycle; Cell Line, Tumor; Coo

2013
Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types.
    Oncotarget, 2015, Oct-06, Volume: 6, Issue:30

    Topics: Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinas

2015
Latent Tuberculosis Infection and the Risk of Subsequent Cancer.
    Medicine, 2016, Volume: 95, Issue:4

    Topics: Adult; Aged; Antitubercular Agents; Case-Control Studies; Female; Humans; Isoniazid; Latent Tubercul

2016
Chelators to the rescue: different horses for different courses!
    Chemical research in toxicology, 2011, Mar-21, Volume: 24, Issue:3

    Topics: Aldehydes; Animals; Deferoxamine; Humans; Hydrazones; Iron Chelating Agents; Iron Overload; Isoniazi

2011
Characterization of Mycobacterium tuberculosis isolated from cancer patients with suspected tuberculosis infection in Egypt: identification, prevalence, risk factors and resistance pattern.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2012, Volume: 18, Issue:11

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Bacteriological Techniques; Child; Drug Resistance,

2012
[Isonicotinic acid hydrazide and neoplasia].
    Rassegna medica, 1952, Volume: 29, Issue:11

    Topics: Animals; Isomerism; Isoniazid; Neoplasms; Neoplasms, Experimental; Niacin; Nicotinic Acids

1952
Therapeutic assays of the Skin and Cancer Unit of the New York University Hospital. VIII. Isonicotinylhydrazine (rimifon) in the treatment of tuberculosis cutis, some other granulomatous processes and miscellaneous dermatoses of doubtful cause.
    The Journal of investigative dermatology, 1953, Volume: 21, Issue:1

    Topics: Hospitals, University; Isoniazid; Neoplasms; New York; Niacin; Nicotinic Acids; Skin Diseases; Tuber

1953
[Isoniazid therapy and cancer of lungs].
    Tuberkulozis kerdesei, 1955, Volume: 8, Issue:3

    Topics: Isomerism; Isoniazid; Lung Neoplasms; Neoplasms; Niacin; Nicotinic Acids

1955
[Effects of isoniazid on pathogenesis of lupus carcinoma].
    Dermatologische Wochenschrift, 1956, Volume: 133, Issue:5

    Topics: Carcinoma; Isomerism; Isoniazid; Lupus Vulgaris; Neoplasms; Niacin; Nicotinic Acids

1956
[Isoniazid therapy of specific lymphomas of the throat].
    Ceskoslovenska otolaryngologie, 1959, Volume: 8, Issue:1

    Topics: Humans; Isoniazid; Lymphoma; Neck; Neoplasms; Pharynx; Staining and Labeling

1959
[Does isonicotinic acid hydrazide induce tumors].
    Deutsche medizinische Wochenschrift (1946), 1960, Sep-09, Volume: 85

    Topics: Carcinogens; Isoniazid; Neoplasms

1960
[Antitumoral action of triethylene melamine-isonicotinic acid hydrazide association on Galliera sarcoma of the rat].
    Bollettino della Societa italiana di biologia sperimentale, 1959, Sep-30, Volume: 35

    Topics: Animals; Isoniazid; Neoplasms; Rats; Sarcoma; Sarcoma, Experimental; Triethylenemelamine

1959
[Inhibitory action of isonicotinic acid hydrazide on the development of Galliera sarcoma in the rat].
    Bollettino della Societa italiana di biologia sperimentale, 1959, Sep-30, Volume: 35

    Topics: Animals; Isoniazid; Neoplasms; Rats; Sarcoma; Sarcoma, Experimental

1959
[On alteration of the growth of Jensen sarcoma by roentgen irradiation in combination with INH].
    Radiobiologia, radiotherapia, 1962, Volume: 3

    Topics: Animals; Biological Phenomena; Isoniazid; Neoplasms; Physiological Phenomena; Radiation Effects; Sar

1962
[New experimental data on the tumor-inducing effect of isonicotinic acid hydrazide (INH)].
    Zeitschrift fur Krebsforschung, 1963, Volume: 65

    Topics: Animals; Isoniazid; Leukemia; Leukemia, Experimental; Leukemia, Myeloid; Lymphoma; Lymphoma, Large B

1963
[CASE OF PULMONARY TUBERCULOSIS MISDIAGNOSED AS LUNG METASTASIS OF MALIGNANT CHORIOCARCINOMA].
    Rinsho hoshasen. Clinical radiography, 1963, Volume: 8

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Choriocarcinoma; Diagnosis, Differ

1963
[PULMONARY TUBERCULOSIS MISDIAGNOSED AS OTHER DISEASES].
    Rinsho hoshasen. Clinical radiography, 1963, Volume: 8

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Diagnosis, Differenti

1963
[RECENT EXPERIMENTAL DATA ON CARCINOGENIC EFFECT OF ISONICOTINIC ACID HYDRAZIDE (INH)].
    Magyar onkologia, 1963, Volume: 7

    Topics: Carcinogens; Humans; Isoniazid; Leukemia; Leukemia, Myeloid; Lung Neoplasms; Lymphoma; Lymphoma, Lar

1963
[ON THE TREATMENT OF DIFFERENT TYPES OF RHEUMATIC DISEASES IN PULMONARY TUBERCULOSIS AND LUNG TUMORS].
    Zeitschrift fur Tuberkulose und Erkrankungen der Thoraxorgane, 1964, Volume: 121

    Topics: Agranulocytosis; Aminosalicylic Acid; Aminosalicylic Acids; Isoniazid; Leukopenia; Lung; Lung Neopla

1964
[ON THE ELECTRON MICROSCOPIC STRUCTURE OF A NEW TRANSPLANTABLE MOUSE ASCITES SARCOMA INDUCED BY ISONICOTINIC ACID HYDRAZIDE (INH)].
    Magyar onkologia, 1964, Volume: 8

    Topics: Ascites; Carcinogens; Electrons; Humans; Isoniazid; Mice; Microscopy; Microscopy, Electron; Neoplasm

1964
[THERAPEUTIC EFFECTS OF A METABOLITE OF PHENYLBUTAZONE (G 27202) IN PRIMARY SEROSITIS].
    La Clinica terapeutica, 1964, Apr-15, Volume: 29

    Topics: Aminopyrine; Blood Sedimentation; Humans; Isoniazid; Neoplasms; Oxyphenbutazone; Peritonitis; Perito

1964
[PRIMARY FIBROSARCOMA OF THE CARDIAC VENTRICLE DIAGNOSED DURING LIFE].
    Orvosi hetilap, 1964, May-31, Volume: 105

    Topics: Anti-Bacterial Agents; Blood Sedimentation; Diuretics; Electrocardiography; Fibrosarcoma; Heart Ausc

1964
INDUCTION OF HEPATOMAS IN CBA-CB-SE MICE BY HYDRAZINE SULPHATE AND THE LACK OF EFFECT OF CROTON OIL ON TUMOUR INDUCTION IN BALB-C-CB-SE MICE.
    British journal of cancer, 1964, Volume: 13

    Topics: Animals; Carcinoma, Hepatocellular; Croton Oil; Hydrazines; Isoniazid; Isonicotinic Acids; Liver; Li

1964
[ISONICOTINIC ACID HYDRAZIDE AND NEOPLASMS].
    Archives internationales de pharmacodynamie et de therapie, 1964, Nov-01, Volume: 152

    Topics: Antineoplastic Agents; Isoniazid; Neoplasms; Neoplasms, Experimental; Pharmacology; Rats; Research

1964
[CARCINOGENESIS IN LUPUS VULGARIS TREATED WITH VITAMIN D2 AND ISONICOTINIC ACID HYDRAZIDE].
    Dermatologische Wochenschrift, 1965, Jan-02, Volume: 151

    Topics: Carcinogenesis; Carcinogens; Carcinoma; Ergocalciferols; Humans; Isoniazid; Lupus Vulgaris; Lymphati

1965
[RELATIONSHIP BETWEEN CANCER AND TUBERCULOSIS. 2). A RETARDING EFFECT OF BCG INOCULATION FOR TUMOR INDUCTION IN MICE WITH INH OR URETHANE-4 NQO INJECTIONS].
    Kekkaku : [Tuberculosis], 1964, Volume: 39

    Topics: Animals; Antitubercular Agents; BCG Vaccine; Isoniazid; Lung Neoplasms; Mice; Mycobacterium bovis; N

1964
[CANCEROGENIC ACTIVITY OF VARIOUS THERAPEUTIC AGENTS].
    Bollettino chimico farmaceutico, 1964, Volume: 103

    Topics: Carcinogens; Drug Therapy; Humans; Iron; Isoniazid; Neoplasms; Thorium Dioxide; Urethane

1964
CHEMOTHERAPY OF TUBERCULOSIS.
    British medical journal, 1965, Jun-12, Volume: 1, Issue:5449

    Topics: Carcinogens; Drug Therapy; Isoniazid; Lung Neoplasms; Mice; Neoplasms; Toxicology; Tuberculosis; Tub

1965
CARCINOGENESIS OF ISONIAZID IN MICE.
    British medical journal, 1965, Jul-03, Volume: 2, Issue:5452

    Topics: Animals; Carcinogenesis; Carcinogens; Isoniazid; Mice; Neoplasms; Neoplasms, Experimental; Research;

1965
Isoniazid and cancer.
    British medical journal, 1967, Jun-24, Volume: 2, Issue:5555

    Topics: Adult; Animals; Carcinogens; Child; Female; Humans; Isoniazid; Lung Neoplasms; Male; Mice; Neoplasms

1967
Isoniazid therapy in relation to later occurrence of cancer in adults and in infants.
    British medical journal, 1967, Jun-24, Volume: 2, Issue:5555

    Topics: Adult; Aged; Aging; Carcinogens; Child; Child, Preschool; Female; Fetal Death; Fetal Diseases; Human

1967
Cancer hazards of the pharmacy.
    British medical journal, 1967, Oct-28, Volume: 4, Issue:5572

    Topics: Animals; Arsenic; Carcinogens; Estrogens; Griseofulvin; Humans; Hypoglycemic Agents; Isoniazid; Mice

1967
Drug-induced cancer.
    Current topics in pathology. Ergebnisse der Pathologie, 1980, Volume: 69

    Topics: Analgesics; Anesthetics; Animals; Antineoplastic Agents; Arsenic; Griseofulvin; Histamine H1 Antagon

1980
Epidemiological studies of medically used drugs.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 3

    Topics: 2-Naphthylamine; Brain Neoplasms; Epidemiologic Methods; Female; Humans; Isoniazid; Liver Neoplasms;

1980
Late effects following isoniazid therapy.
    American journal of public health, 1980, Volume: 70, Issue:9

    Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Isoniazid; Liver Cirrhosis; Neoplasms; Time Fa

1980
Thioether excretion, urinary mutagenicity, and metabolic phenotype in smokers.
    Journal of toxicology and environmental health, 1994, Volume: 43, Issue:3

    Topics: Acetylation; Adult; Biomarkers; Creatinine; Debrisoquin; Female; Genetic Predisposition to Disease;

1994
Prevention of infections in patients with neoplastic disease: use of a historical model for developmental strategies.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 17 Suppl 2

    Topics: Humans; Immunocompromised Host; Infection Control; Isoniazid; Models, Biological; Neoplasms; Tubercu

1993
The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents II: the mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone.
    Blood, 1997, Apr-15, Volume: 89, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Benzaldehydes; Cell Cycle; Cell Division; Deferoxamine; DNA Fragme

1997
Childhood cancer and drugs in pregnancy.
    British medical journal, 1979, Mar-17, Volume: 1, Issue:6165

    Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Fetus; Humans; Infant; Infant, Newborn

1979
Is isonicotinic acid hydrazide (INH) carcinogenic to man? A 24-year follow-up of 3371 tuberculosis cases.
    Ecotoxicology and environmental safety, 1979, Volume: 3, Issue:4

    Topics: Alcohol Drinking; Carcinogens; Denmark; Female; Follow-Up Studies; Humans; Isoniazid; Lung Neoplasms

1979
Isoniazid exposure in relation to cancer incidence and mortality in a cohort of tuberculosis patients.
    International journal of epidemiology, 1979, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Canada; Carcinogens; Female; Follow-Up Studies; Humans; Isoniazid; Lung Neoplasms

1979
[Carcinogenic properties of hydrazines].
    Orvosi hetilap, 1977, Dec-11, Volume: 118, Issue:50

    Topics: Animals; Carcinogens; Cricetinae; Humans; Hydrazines; Isoniazid; Neoplasms; Rats

1977
Secondary mania: manic syndromes associated with antecedent physical illness or drugs.
    Archives of general psychiatry, 1978, Volume: 35, Issue:11

    Topics: Adrenal Cortex Hormones; Adult; Bipolar Disorder; Bromides; Epilepsy, Temporal Lobe; Humans; Isoniaz

1978
An assessment of the carcinogenicity of isoniazid in patients with pulmonary tuberculosis.
    Tubercle, 1976, Volume: 57, Issue:1

    Topics: Adolescent; Adult; Animals; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Isoniaz

1976
Role of iron in the proliferation of the established human tumor cell lines U-937 and K-562: effects of suramin and a lipophilic iron chelator (PIH).
    Scandinavian journal of haematology, 1986, Volume: 37, Issue:5

    Topics: Cell Cycle; Cell Division; Cell Line; DNA; Humans; Intracellular Membranes; Iron; Iron Chelating Age

1986
Theoretical involvement of vitamin B6 in tumour initiation.
    Medical hypotheses, 1985, Volume: 16, Issue:4

    Topics: DNA; DNA Repair; Estrogens; Female; Folic Acid Deficiency; Humans; Isoniazid; Neoplasms; Niacin; Thy

1985
Use of computerized record linkage in follow-up studies of cancer epidemiology in Canada.
    National Cancer Institute monograph, 1985, Volume: 67

    Topics: Breast Neoplasms; Canada; Computers; Fluoroscopy; Follow-Up Studies; Humans; Isoniazid; Lung Neoplas

1985
Additive toxicity of vincristine and other drugs for the peripheral nervous system. Three case reports.
    Acta neurologica Belgica, 1971, Volume: 71, Issue:6

    Topics: Adult; Asparaginase; Female; Humans; Isoniazid; Male; Middle Aged; Neoplasms; Peripheral Nerves; Per

1971
Letter: Isoniazid and cancer risks.
    JAMA, 1974, Dec-02, Volume: 230, Issue:9

    Topics: Animals; Child; Child, Preschool; Humans; Isoniazid; Male; Neoplasms; Tuberculosis; Urinary Bladder

1974
Complications of BCG immunotherapy in patients with cancer.
    The New England journal of medicine, 1973, Oct-18, Volume: 289, Issue:16

    Topics: BCG Vaccine; Fever; Humans; Immunotherapy; Injections; Injections, Intradermal; Isoniazid; Jaundice;

1973
Fever of unexplained origin in patients with cancer.
    European journal of cancer, 1973, Volume: 9, Issue:9

    Topics: Bacterial Infections; Carbenicillin; Cephalothin; Endocarditis; Ethambutol; Female; Fever of Unknown

1973
Extrapolation of experimental carcinogenicity to the reality of industrial exposure.
    The Annals of occupational hygiene, 1972, Volume: 15, Issue:1

    Topics: Animals; Carbon Tetrachloride; Carcinogens; Chemical Industry; Cyclamates; Drug Contamination; Envir

1972
Methotrexate plus Bacillus Calmette-Guérin (BCG) and isoniazid in the treatment of cancer of the head and neck.
    American journal of surgery, 1972, Volume: 124, Issue:4

    Topics: Adult; Aged; BCG Vaccine; Carcinoma, Squamous Cell; Cyclophosphamide; Head; Head and Neck Neoplasms;

1972
Lupus vulgaris, isoniazid, and cancer. The frequency of cancer deaths in 245 isoniazid-treated lupus vulgaris patients with an average observation period of 12 years.
    Scandinavian journal of respiratory diseases, 1968, Volume: 49, Issue:4

    Topics: Adult; Age Factors; Aged; Breast Neoplasms; Carcinoma, Squamous Cell; Colonic Neoplasms; Female; Hum

1968
[A clinical study of the oncogenic properties of isoniazid and its derivatives].
    Rivista di clinica pediatrica, 1967, Volume: 80, Issue:5

    Topics: Animals; Humans; Isoniazid; Neoplasms; Neoplasms, Experimental; Tuberculosis, Meningeal

1967
[On the present status of chemotherapy of lung tuberculosis, especially in ambulatory use].
    Zeitschrift fur Tuberkulose und Erkrankungen der Thoraxorgane, 1967, Volume: 126, Issue:1

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Child; Child, Preschool; Ethionamide; Female; Humans; Infa

1967
Tumors (re)shape biotic interactions within ecosystems: Experimental evidence from the freshwater cnidarian Hydra.
    The Science of the total environment, 2022, Jan-10, Volume: 803

    Topics: Animals; Cnidaria; Ecosystem; Fresh Water; Hydra; Neoplasms

2022
Dynamic interactions within the host-associated microbiota cause tumor formation in the basal metazoan Hydra.
    PLoS pathogens, 2020, Volume: 16, Issue:3

    Topics: Animals; Carcinogenesis; Hydra; Leptospiraceae; Microbiota; Neoplasms; Pseudomonas

2020
Naturally occurring tumours in the basal metazoan Hydra.
    Nature communications, 2014, Jun-24, Volume: 5

    Topics: Animals; Biological Evolution; Eukaryota; Female; Hydra; Male; Neoplasms; Vertebrates

2014
Vegetative reproduction by budding in Hydria: a perspective on tumors.
    Perspectives in biology and medicine, 1977,Summer, Volume: 20, Issue:4

    Topics: Animals; Cell Differentiation; Cell Division; Colchicine; Hydra; Models, Biological; Morphogenesis;

1977