isoniazid has been researched along with Behavior Disorders in 76 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Family and personal history of mental illness are also predisposing factors." | 1.31 | [Behavioral disorders after treatment with isoniazid]. ( Djibo, A; Lawan, A, 2001) |
| "Eleven patients with Huntington's disease were treated with high doses of isoniazid." | 1.27 | Quantitative evaluation of functional capacity during isoniazid therapy in Huntington's disease. ( Holzer, G; Schimrigk, K; Stober, T; Ziegler, B, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 73 (96.05) | 18.7374 |
| 1990's | 2 (2.63) | 18.2507 |
| 2000's | 1 (1.32) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FLAHERTY, JA | 1 |
| HUNTER, RA | 1 |
| KRIESER, AE | 1 |
| SANDERSON, AG | 1 |
| VIK, M | 1 |
| MYERS, JA | 1 |
| BARNARD, RD | 1 |
| CHU, J | 1 |
| LETAILLEUR, M | 1 |
| SCHMIDT, P | 1 |
| CONRAD, K | 1 |
| SCHEIB, E | 1 |
| TESSING-ERICSSON, G | 1 |
| WILSON, WP | 1 |
| NUGEL, A | 1 |
| LIPPI-FRANCESCONI, PL | 1 |
| HUNT, B | 1 |
| WASSERSUG, JD | 1 |
| ROVESCALLI, A | 1 |
| CANESI, MT | 1 |
| SIMON, R | 1 |
| POROT, M | 3 |
| FRANK, F | 1 |
| KISSEL, P | 1 |
| ARNOULD, G | 1 |
| HARTEMANN, P | 1 |
| WEISS, M | 1 |
| SALZMAN, L | 1 |
| ALBY, JM | 1 |
| KIERSCH, TA | 1 |
| PLEASURE, H | 1 |
| CELLERINO, RJ | 1 |
| CAMPOS, RM | 1 |
| WEISBERG, MM | 1 |
| MENDES, F | 1 |
| Delay, J | 1 |
| Bourguignon, A | 1 |
| Buisson, J | 1 |
| Henne, M | 1 |
| HEWAT, JK | 1 |
| LEACH, PW | 1 |
| SIMPSON, RW | 1 |
| MACCAGNANI, G | 1 |
| LEHMANN-GRUBE, F | 1 |
| Lazarou, P | 2 |
| Papaemmanuel, S | 2 |
| DU PLESSIS, JJ | 1 |
| PAULEIKHOFF, B | 1 |
| WEINGARTNER, L | 1 |
| JACKSON, SL | 1 |
| HARE, EH | 1 |
| ORGANICK, AB | 1 |
| BANSHCHIKOV, VM | 1 |
| STOLLIAROV, GV | 1 |
| BURNETT, PC | 1 |
| BRODIE, D | 1 |
| SMITH, JA | 1 |
| DUNCAN, H | 1 |
| KERR, D | 1 |
| GRAHMANN, H | 1 |
| PETERS, UH | 1 |
| KANE, FJ | 1 |
| TAYLOR, TW | 1 |
| BLOMQUIST, ET | 1 |
| MOLINA, C | 1 |
| GIRARD, J | 1 |
| MODAI, J | 1 |
| ASPINALL, DL | 1 |
| SELLERS, RD | 1 |
| SCOTT, WR | 1 |
| ROOT, HD | 1 |
| PERRY, JF | 1 |
| KUBICKI, S | 1 |
| IBE, K | 1 |
| GOETZE, W | 1 |
| KNAPP, A | 1 |
| PFAFFENBERG, R | 1 |
| SALZER, HM | 1 |
| LURIE, ML | 1 |
| VENCOVSKY, E | 1 |
| PETROVA, J | 1 |
| JOHNSON, JA | 1 |
| NAESS, K | 1 |
| ROBIE, TR | 1 |
| WROBLEWSKI, F | 1 |
| ALBANO, E | 1 |
| Stober, T | 1 |
| Schimrigk, K | 1 |
| Holzer, G | 1 |
| Ziegler, B | 1 |
| Poon, WS | 1 |
| Ahuja, A | 1 |
| Li, AK | 1 |
| Griggs, H | 1 |
| Cammarata, SK | 1 |
| Djibo, A | 1 |
| Lawan, A | 1 |
| Sorokina, TT | 1 |
| Newton, RW | 1 |
| Diukov, VA | 1 |
| Mitchell, JR | 1 |
| Long, MW | 1 |
| Thorgeirsson, UP | 1 |
| Jollow, DJ | 1 |
| Bleandonu, G | 2 |
| Boye, J | 2 |
| Schulze, B | 1 |
| Jansén, CT | 1 |
| Havu, VK | 1 |
| Ganev, G | 1 |
| Karamalakov, L | 1 |
| Milenkov, K | 1 |
| Ianachkova, M | 1 |
| Sakhatchieva, L | 1 |
| Kiuchukova, P | 1 |
| Roĭlev, I | 1 |
| Naumov, I | 1 |
| Cheshmedzhiev, P | 1 |
| Dochkov, Zh | 1 |
| Ferebee, SH | 1 |
| Douady, D | 1 |
| Jeanguyot, MT | 1 |
| Lacalmontie, J | 1 |
| Rosembaum, SB | 1 |
| Thibier, R | 1 |
| Riska, N | 1 |
| Mattila, MJ | 1 |
| Takki, S | 1 |
| Renier, JC | 1 |
| Oury, M | 1 |
| Bregeon, C | 1 |
| Tuchais, E | 1 |
| Renard, J | 1 |
| Bertrand, Y | 1 |
| Puvinel, B | 1 |
| Mezard, F | 1 |
| Kuznetsova, NI | 1 |
| Sorokina, IN | 1 |
2 reviews available for isoniazid and Behavior Disorders
| Article | Year |
|---|---|
[Hereditary biochemical polymorphism and hereditary pathology (review of the literature)].
Topics: ABO Blood-Group System; Animals; Antipsychotic Agents; Blood Proteins; Dopamine beta-Hydroxylase; Dr | 1978 |
[Pharmacogenetic research in clinical psychiatry].
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Chlorpromazine; Cholinesteras | 1976 |
2 trials available for isoniazid and Behavior Disorders
| Article | Year |
|---|---|
[Prophylaxis of neuroleptic parkonsonism with the Bulgarian drug INKhA-17 (Paabainkh) and bellazon].
Topics: Bulgaria; Chlorpromazine; Clinical Trials as Topic; Humans; Isoniazid; Mental Disorders; Parasympath | 1968 |
Long-term effects of isoniazid prophylaxis.
Topics: Adolescent; Adult; Aged; Alaska; Child; Child, Preschool; Clinical Trials as Topic; Female; Follow-U | 1968 |
72 other studies available for isoniazid and Behavior Disorders
| Article | Year |
|---|---|
[The psychiatric use of isonicotinic acid hydrazide].
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Alcoholic; Psychotic Disorders | 1952 |
Confusional psychosis with residual organic cerebral impairment following isoniazid therapy.
Topics: Confusion; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Substance-Induced; Psych | 1952 |
Effects of isonicotinic acid hydrazide in mentally ill patients.
Topics: Isoniazid; Mental Disorders; Mentally Ill Persons; Niacin; Nicotinic Acids; Tuberculosis; Tuberculos | 1953 |
Abnormal psychic manifestations during isoniazid therapy for adaptative disease.
Topics: Isomerism; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychotic Disorders | 1953 |
Toxic psychosis due to overdosage of isonicotinic acid hydrazide.
Topics: Humans; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Substance-Induced; Psychoti | 1953 |
[Mental and neurological disorders caused by toxic effects of isonicotinic acid hydrazide].
Topics: Isoniazid; Mental Disorders; Nervous System Diseases; Niacin; Nicotinic Acids; Psychoses, Substance- | 1953 |
[Acute psychosis subsequent to isonicotinic acid hydrazide treatment].
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Substance-Induced; Psychotic Disord | 1953 |
[Three cases of psychosis during isonicotinic acid hydrazide therapy].
Topics: Isomerism; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Substance-Induced; Psych | 1953 |
Isonicotinic acid hydrazide in nontuberculous mental patients.
Topics: Isoniazid; Mental Disorders; Mentally Ill Persons; Niacin; Nicotinic Acids; Psychosurgery; Psychothe | 1953 |
[Isonicotinic acid hydrazide in tuberculosis in mental patients; neuropsychiatric findings].
Topics: Isoniazid; Mental Disorders; Mentally Ill Persons; Niacin; Nicotinic Acids; Tuberculosis; Tuberculos | 1953 |
[Use of isonicotinic acid hydrazide in various psychopathic disorders].
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychosurgery; Psychotherapy | 1953 |
Effects of isoniazid on patients with tuberculosis and mental illness.
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Tuberculosis; Tuberculosis, Pulmonary | 1953 |
[The electrophoretic curve in tuberculosis with psychosis during isonicotinic acid hydrazide therapy].
Topics: Blood Proteins; Electrophoresis; Humans; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psych | 1953 |
An investigation of some psychological effects accompanying isoniazid therapy on tuberculous patients.
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Tuberculosis | 1954 |
[Streptomycin, isoniazid and psychiatric disorders].
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychotherapy; Streptomycin; Tuberculosis | 1954 |
[Toxic, outbreak and course of a psychosis caused by isoniazid therapy].
Topics: Disease Outbreaks; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Substance-Induce | 1954 |
[Isoniazid and psyche].
Topics: Electroconvulsive Therapy; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychotherapy; Tube | 1954 |
[Neuro-activity and neurotoxicity of isoniazid (I.N.H.)].
Topics: Electroconvulsive Therapy; Isoniazid; Mental Disorders; Nervous System; Niacin; Nicotinic Acids; Psy | 1954 |
Paranoid state during therapy with isoniazid in pulmonary.
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Substance-Induced; Psychotic Disord | 1954 |
[Isoniazid as psychiatric therapy].
Topics: Electroconvulsive Therapy; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychosurgery; Psyc | 1954 |
Toxic organic psychoses due to isoniazid therapy.
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Substance-Induced; Psychotic Disord | 1954 |
Psychiatric and neurological side-effects of isoniazid and iproniazid.
Topics: Disease; Iproniazid; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychotic Disorders; Seiz | 1954 |
[Effect of isonicotinic acid hydrazide on tuberculous patients with mental disorders].
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Tuberculosis; Tuberculosis, Pulmonary | 1955 |
[Psychoses caused by isoniazid].
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Substance-Induced; Psychotic Disord | 1955 |
[Mental disorders in the course of tubercular meningitis treated with isoniazid].
Topics: Humans; Isoniazid; Mental Disorders; Tuberculosis; Tuberculosis, Meningeal | 1955 |
Chlorpromazine, reserpine, and isoniazid treatment in mental disorder; a preliminary communication.
Topics: Chlorpromazine; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychosurgery; Psychotherapy; | 1955 |
[Results of isoniazid in psychiatry; clinical study].
Topics: Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychiatry; Tuberculosis; Tuberculosis, Pulmon | 1955 |
[Psychosis caused by isoniazid].
Topics: Isomerism; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychoses, Substance-Induced; Psych | 1956 |
[Symptomatic mania in a 3 years old child in the course of isoniazide therapy].
Topics: Child; Humans; Infant; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorder | 1956 |
[Symptomatic mania in a 3 years old child in the course of isoniazide therapy].
Topics: Child; Humans; Infant; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorder | 1956 |
[Symptomatic mania in a 3 years old child in the course of isoniazide therapy].
Topics: Child; Humans; Infant; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorder | 1956 |
[Symptomatic mania in a 3 years old child in the course of isoniazide therapy].
Topics: Child; Humans; Infant; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorder | 1956 |
[Manic psychosis during treatment with isoniazid (I.N.H.) in a pulmonary tuberculosis patient].
Topics: Humans; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders | 1956 |
[Manic psychosis during treatment with isoniazid (I.N.H.) in a pulmonary tuberculosis patient].
Topics: Humans; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders | 1956 |
[Manic psychosis during treatment with isoniazid (I.N.H.) in a pulmonary tuberculosis patient].
Topics: Humans; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders | 1956 |
[Manic psychosis during treatment with isoniazid (I.N.H.) in a pulmonary tuberculosis patient].
Topics: Humans; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders | 1956 |
Tuberculosis as a possible aetiological factor in mental disorder, and the place of isoniazid in treatment; with five illustrative case reports.
Topics: Humans; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders; Tuberculosis | 1957 |
[Psychopathological particularities of a psychosis having occurred during isoniazid treatment].
Topics: Humans; Isoniazid; Mental Disorders; Psychopathology; Psychoses, Substance-Induced; Psychotic Disord | 1957 |
[Isoniazid toxicity in childhood].
Topics: Child; Humans; Infant; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorder | 1957 |
Psychosis due to isoniazid.
Topics: Humans; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders | 1957 |
Psychotic reactions due to anti-tuberculous drugs.
Topics: Humans; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders; Streptomycin | 1958 |
Toxic psychosis due to isoniazid; report of three cases with studies of patterns of isoniazid inactivation in the serum.
Topics: Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders; Tuberculosis; Tuberc | 1959 |
[Psychoses caused by antitubercular agents-isoniazid and improniazid--and use of these preparations in the treatment of mental disorders].
Topics: Antitubercular Agents; Humans; Iproniazid; Isoniazid; Mental Disorders; Psychoses, Substance-Induced | 1961 |
Report on the use of cycloserine and isoniazid in twenty-seven cases of pulmonary tuberculosis in psychotic patients.
Topics: Cycloserine; Isoniazid; Mental Disorders; Psychotic Disorders; Tuberculosis; Tuberculosis, Pulmonary | 1961 |
A trial of nialamide in chronically ill mental patients.
Topics: Chronic Disease; Electroconvulsive Therapy; Humans; Isoniazid; Mental Disorders; Mentally Ill Person | 1959 |
Toxic psychosis due to isoniazid.
Topics: Humans; Isoniazid; Medical Records; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disord | 1962 |
[On psychotic manifestations following INH withdrawal].
Topics: Humans; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Disorders | 1962 |
Mania associated with the use of I.N.H. and cocaine.
Topics: Bipolar Disorder; Cocaine; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psychotic Diso | 1963 |
PROGRAM AIMED AT ERADICATION OF TUBERCULOSIS.
Topics: Adolescent; Black People; Child; Communicable Disease Control; Geriatrics; Humans; Infant; Isoniazid | 1963 |
[VITAMIN B DEFICIENCIES IN PULMONARY TUBERCULOUS PATIENTS TREATED BY ANTIBACILLARY MEDICATIONS].
Topics: Aspartate Aminotransferases; Clinical Enzyme Tests; Dermatology; Diagnosis; Gynecomastia; Humans; Is | 1963 |
[PSYCHIC DISORDERS DUE TO ANTITUBERCULAR ANTIBIOTICS].
Topics: Antibiotics, Antitubercular; Cycloserine; Isoniazid; Mental Disorders; Streptomycin; Toxicology | 1964 |
[ROLE OF METABOLIC DISORDERS IN THE DETERMINISM OF CERTAIN COMPLICATIONS OF ANTITUBERCULAR CHEMOTHERAPY].
Topics: Antitubercular Agents; Avitaminosis; Dermatology; Ethionamide; Gastroenterology; Guinea Pigs; Humans | 1964 |
MULTIPLE DEFICIENCY STATE ASSOCIATED WITH ISONIAZID THERAPY.
Topics: Anxiety; Depression; Ethionamide; Feeding and Eating Disorders; Isoniazid; Mental Disorders; Niacin; | 1964 |
BILATERAL PULMONARY RESECTION FOR TUBERCULOSIS.
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Biomedical Research; Brain; Brain Damage, Chronic; Drug T | 1964 |
[EEG CHANGES IN A PSYCHOSIS CAUSED BY INH AND AFTER A SUICIDE ATTEMPT WITH NICOTEBEN].
Topics: Adolescent; Electroencephalography; Isoniazid; Mental Disorders; Psychoses, Substance-Induced; Psych | 1964 |
[TRYPTOPHAN STRESS AND INH METABOLISM IN THE TUBERCULOSIS DIABETIC].
Topics: Diabetes Mellitus; Drug Therapy; Humans; Isoniazid; Mental Disorders; Toxicology; Tryptophan; Tuberc | 1964 |
Depressive states treated with isonicotinyl hydrazide (isoniazid); a follow-up study.
Topics: Bipolar Disorder; Depression; Depressive Disorder; Follow-Up Studies; Isoniazid; Mental Disorders; N | 1955 |
[Psychological disorders in isoniazid therapy].
Topics: Isomerism; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids | 1955 |
Clinical evaluation of nialamide in hospitalized and non-hospitalized patients.
Topics: Counseling; Electroconvulsive Therapy; Humans; Isoniazid; Mental Disorders; Nialamide; Psychosurgery | 1959 |
[Psychic disorders caused by isonizid].
Topics: Humans; Isoniazid; Mental Disorders | 1960 |
Transaminase controlled nialamide.
Topics: Electroconvulsive Therapy; Humans; Isoniazid; Mental Disorders; Nialamide; Psychosurgery; Psychother | 1959 |
Quantitative evaluation of functional capacity during isoniazid therapy in Huntington's disease.
Topics: Adult; Disability Evaluation; Female; Humans; Huntington Disease; Isoniazid; Male; Mental Disorders; | 1983 |
Optochiasmatic tuberculoma causing progressive visual failure: when has medical treatment failed?
Topics: Child, Preschool; Dexamethasone; Drug Therapy, Combination; Female; Humans; Isoniazid; Mental Disord | 1993 |
Acute mental changes in a 68-year-old man with bladder cancer.
Topics: Administration, Intravesical; Aged; BCG Vaccine; Carcinoma, Transitional Cell; Confusion; Hematuria; | 1998 |
[Behavioral disorders after treatment with isoniazid].
Topics: Aging; Alcoholism; Antitubercular Agents; Behavior; Contraindications; Diabetes Mellitus; Female; Hu | 2001 |
Side effects of drugs used to treat tuberculosis.
Topics: Aminosalicylic Acids; Animals; Antitubercular Agents; Capreomycin; Chemical and Drug Induced Liver I | 1975 |
Acetylation rates and monthly liver function tests during one year of isoniazid preventive therapy.
Topics: Acetylation; Adult; Aged; Antibodies, Antinuclear; Aspartate Aminotransferases; Bilirubin; Chemical | 1975 |
Psychiatric side effects of nonpsychiatric drugs.
Topics: Aminophylline; Analgesics; Anti-Anxiety Agents; Anti-Bacterial Agents; Anticonvulsants; Antiemetics; | 1971 |
[Neuropsychiatric incidences in antitubercular treatment consisting of isoniazid or isoniazid and ethionamide (8 cases)].
Topics: Acidosis; Adult; Alcoholism; Ammonia; Avitaminosis; Carboxy-Lyases; Chromatography, Paper; Chromatog | 1969 |
[Clinical relevance of photosensitivity in psychiatric EEG diagnosis].
Topics: Bipolar Disorder; Brain; Electroencephalography; Epilepsy; Humans; Isoniazid; Light; Mental Disorder | 1974 |
[INH-induced pellagra].
Topics: Adult; Child, Preschool; Female; Humans; Isoniazid; Male; Mental Disorders; Pellagra; Sex Factors; T | 1972 |
[Role of psychotherapy in a group of adolescents with tuberculosis].
Topics: Adolescent; Adult; Female; France; Humans; Isoniazid; Long-Term Care; Male; Mental Disorders; Psycho | 1970 |
Tolerance to cycloserine.
Topics: Adult; Aged; Aminosalicylic Acids; Cycloserine; Drug Tolerance; Ethionamide; Female; Humans; Isoniaz | 1970 |
Half-lives of isoniazid and salicylic acid in serum and their modification by different drugs in psychiatric patients.
Topics: Adult; Blood Proteins; Chlorpromazine; Humans; Isoniazid; Mental Disorders; Middle Aged; Protein Bin | 1969 |
[The algodystrophies caused by antituberculous chemotherapy. Study of 24 cases].
Topics: Age Factors; Alcoholism; Aminosalicylic Acids; Barbiturates; Drug Synergism; Ethionamide; Female; Hu | 1969 |
[Neuropsychiatric repercussions of antitubercular treatment with isoniazid, or isoniazid and ethionamide (apropos of 8 cases)].
Topics: Adult; Coma; Ethionamide; Female; Humans; Isoniazid; Male; Mental Disorders; Middle Aged; Neurologic | 1969 |
[On the usefulness of vitamin B 6 during treatment with isoniazid].
Topics: Animals; Humans; Isoniazid; Mental Disorders; Polyneuropathies; Transaminases; Tuberculosis, Pulmona | 1967 |
[On the effect of antibodies against brain tissue on the intracerebral penetration of drugs].
Topics: Animals; Antibodies; Brain; Brain Chemistry; Complement Fixation Tests; Humans; Immune Sera; Isoniaz | 1968 |