isoniazid has been researched along with Alcoholism in 83 studies
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.
hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC).
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alcohol use is common among people with HIV and is a risk factor for tuberculosis disease and non-adherence to isoniazid preventive therapy (IPT)." | 9.69 | Financial incentives for reduced alcohol use and increased isoniazid adherence during tuberculosis preventive therapy among people with HIV in Uganda: an open-label, factorial randomised controlled trial. ( Adong, J; Beesiga, B; Bryant, K; Chamie, G; Emenyonu, NI; Fatch, R; Gandhi, M; Hahn, JA; Havlir, DV; Kamya, MR; Kekibiina, A; Lodi, S; Marson, K; McDonell, MG; Muyindike, WR; Thirumurthy, H, 2023) |
| "We retrospectively evaluated the use of disulfiram among alcoholic patients being treated for active tuberculosis." | 7.71 | Lack of toxicity from concomitant directly observed disulfiram and isoniazid-containing therapy for active tuberculosis. ( Breese, P; Burman, WJ; Cohn, D; Reves, R; Terra, M, 2002) |
| "Alcohol use is common among people with HIV and is a risk factor for tuberculosis disease and non-adherence to isoniazid preventive therapy (IPT)." | 5.69 | Financial incentives for reduced alcohol use and increased isoniazid adherence during tuberculosis preventive therapy among people with HIV in Uganda: an open-label, factorial randomised controlled trial. ( Adong, J; Beesiga, B; Bryant, K; Chamie, G; Emenyonu, NI; Fatch, R; Gandhi, M; Hahn, JA; Havlir, DV; Kamya, MR; Kekibiina, A; Lodi, S; Marson, K; McDonell, MG; Muyindike, WR; Thirumurthy, H, 2023) |
| "A history of alcoholism is often regarded as a relative contraindication to the use of isoniazid and rifampin in patients with tuberculosis." | 5.05 | Rifampin-isoniazid therapy of alcoholic and nonalcoholic tuberculous patients in a U.S. Public Health Service Cooperative Therapy Trial. ( Banner, AS; Cross, FS; Long, MW; Snider, DE, 1980) |
| "Isoniazid preventive therapy (IPT) reduces mortality among people living with HIV (PLHIV) and is recommended for those without active tuberculosis (TB) symptoms." | 3.88 | Isoniazid Preventive Therapy for People With HIV Who Are Heavy Alcohol Drinkers in High TB-/HIV-Burden Countries: A Risk-Benefit Analysis. ( Ellner, JJ; Freiman, JM; Hahn, JA; Horsburgh, CR; Jacobson, KR; Linas, BP; Muyindike, WR, 2018) |
| "We retrospectively evaluated the use of disulfiram among alcoholic patients being treated for active tuberculosis." | 3.71 | Lack of toxicity from concomitant directly observed disulfiram and isoniazid-containing therapy for active tuberculosis. ( Breese, P; Burman, WJ; Cohn, D; Reves, R; Terra, M, 2002) |
| "We report a case of isoniazid induced convulsions in 35 years old male alcoholic and smoker patient receiving intensive phase therapy for pulmonary tuberculosis." | 1.42 | Isoniazid induced convulsions at therapeutic dose in an alcoholic and smoker patient. ( Aiwale, AS; Barvaliya, MJ; Jha, PR; Patel, UA; Tripathi, C, 2015) |
| " In this article, a case series is presented to illustrate the value of individualized TB drug dosing in four patients with low TB drug concentrations." | 1.38 | Therapeutic drug monitoring in the treatment of tuberculosis patients. ( Aarnoutse, R; Boeree, M; Ijdema, D; Magis-Escurra, C; van den Boogaard, J, 2012) |
| "Isoniazid is an efficacious treatment for latent tuberculosis." | 1.32 | Use of isoniazid for latent tuberculosis infection in a public health clinic. ( LoBue, PA; Moser, KS, 2003) |
| "Family and personal history of mental illness are also predisposing factors." | 1.31 | [Behavioral disorders after treatment with isoniazid]. ( Djibo, A; Lawan, A, 2001) |
| "Although there was an excess of alcohol abusers in the LTT-positive group, the probability of developing liver dysfunction amongst alcohol abusers in that group was twice as great as for LTT-negative alcohol abusers." | 1.26 | The predictive value of the lymphocyte transformation test in isoniazid-associated hepatitis. ( McPhilips-Feener, S; Rutherford, WJ; Warrington, RJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (78.31) | 18.7374 |
| 1990's | 6 (7.23) | 18.2507 |
| 2000's | 5 (6.02) | 29.6817 |
| 2010's | 5 (6.02) | 24.3611 |
| 2020's | 2 (2.41) | 2.80 |
| Authors | Studies |
|---|---|
| Muyindike, WR | 3 |
| Fatch, R | 2 |
| Cheng, DM | 1 |
| Emenyonu, NI | 2 |
| Forman, L | 1 |
| Ngabirano, C | 1 |
| Adong, J | 2 |
| Linas, B | 1 |
| Jacobson, KR | 2 |
| Hahn, JA | 3 |
| Chamie, G | 1 |
| Kekibiina, A | 1 |
| Beesiga, B | 1 |
| Marson, K | 1 |
| Lodi, S | 1 |
| Thirumurthy, H | 1 |
| McDonell, MG | 1 |
| Gandhi, M | 1 |
| Bryant, K | 1 |
| Havlir, DV | 1 |
| Kamya, MR | 1 |
| Mukherjee, TI | 1 |
| Hirsch-Moverman, Y | 1 |
| Saito, S | 1 |
| Gadisa, T | 1 |
| Melaku, Z | 1 |
| Howard, AA | 1 |
| Freiman, JM | 1 |
| Horsburgh, CR | 1 |
| Ellner, JJ | 1 |
| Linas, BP | 1 |
| Hsia, YC | 1 |
| Naseri, A | 1 |
| Schallhorn, JM | 1 |
| Aiwale, AS | 1 |
| Patel, UA | 1 |
| Barvaliya, MJ | 1 |
| Jha, PR | 1 |
| Tripathi, C | 1 |
| Magis-Escurra, C | 1 |
| van den Boogaard, J | 1 |
| Ijdema, D | 1 |
| Boeree, M | 1 |
| Aarnoutse, R | 1 |
| Burman, WJ | 1 |
| Terra, M | 1 |
| Breese, P | 1 |
| Cohn, D | 1 |
| Reves, R | 1 |
| LoBue, PA | 1 |
| Moser, KS | 1 |
| DESPIERRES, G | 1 |
| PHELIP, H | 1 |
| CAJGFINGER, H | 1 |
| PHILBERT, M | 2 |
| SCHWOB, RA | 2 |
| LEVENDEL, L | 1 |
| VARADY, T | 1 |
| BEDE, L | 1 |
| KAROLYI, A | 1 |
| WANAT-KONDRATOWICZ, W | 1 |
| HUETTL, T | 1 |
| LANYI, M | 1 |
| KADAR, A | 1 |
| COTTIN, S | 1 |
| COZAN, R | 1 |
| VERAN, P | 1 |
| LESTER, D | 1 |
| CHEUNG, OT | 1 |
| OROZCO, W | 1 |
| Fyfe, AJ | 1 |
| Soutar, RL | 1 |
| Sokolova, GB | 2 |
| Ziia, AV | 1 |
| Suvorova, VI | 1 |
| Braude, VI | 1 |
| Glik, MS | 1 |
| Cross, FS | 1 |
| Long, MW | 1 |
| Banner, AS | 1 |
| Snider, DE | 1 |
| Engbaek, HC | 3 |
| Heckscher, T | 1 |
| Højgaard, C | 1 |
| Larsen, SO | 3 |
| Rasmussen, KN | 3 |
| Vergmann, B | 3 |
| Thaler, H | 1 |
| Warrington, RJ | 1 |
| McPhilips-Feener, S | 1 |
| Rutherford, WJ | 1 |
| Bogaerts, Y | 1 |
| Elinck, W | 1 |
| van Renterghem, D | 1 |
| Pauwels, R | 1 |
| van der Straeten, M | 1 |
| Kiblawi, SS | 1 |
| Jay, SJ | 1 |
| Stonehill, RB | 1 |
| Norton, J | 1 |
| Ozick, LA | 1 |
| Jacob, L | 1 |
| Comer, GM | 1 |
| Lee, TP | 1 |
| Ben-Zvi, J | 1 |
| Donelson, SS | 1 |
| Felton, CP | 1 |
| Sanna, E | 1 |
| Serra, M | 1 |
| Cossu, A | 1 |
| Colombo, G | 1 |
| Follesa, P | 1 |
| Cuccheddu, T | 2 |
| Concas, A | 2 |
| Biggio, G | 2 |
| Cárdenas Rodríguez, M | 1 |
| Pérez Gómez, P | 1 |
| Lozano Mera, L | 1 |
| Rothe, TB | 1 |
| Karrer, W | 1 |
| Mascia, MP | 1 |
| Floris, S | 1 |
| Mostallino, MC | 1 |
| Perra, C | 1 |
| Satta, S | 1 |
| Ishikawa, Y | 1 |
| Djibo, A | 1 |
| Lawan, A | 1 |
| Oldershausen v, HF | 1 |
| Goedde, HW | 1 |
| Kuntz, HD | 1 |
| Rausch, V | 1 |
| Edsall, JR | 1 |
| Awe, RJ | 1 |
| Bunyan, SB | 1 |
| Hackney, RL | 1 |
| Iseman, MD | 1 |
| Reagan, WP | 1 |
| Matthiessen, W | 1 |
| Wundschock, M | 1 |
| Radenbach, KL | 1 |
| Göbel, D | 1 |
| Jungbluth, H | 1 |
| Kropp, R | 1 |
| Ortenberg, ZA | 1 |
| Chiancone, FM | 1 |
| Bailey, WC | 1 |
| Sellers, CA | 1 |
| Sutton, FD | 1 |
| Sheehy, TW | 1 |
| Maetz, HM | 1 |
| Grönhagen-Riska, C | 1 |
| Hellstrom, PE | 1 |
| Fröseth, B | 1 |
| Marrie, TJ | 1 |
| Hershfield, ES | 1 |
| Buckingham, WB | 1 |
| Stratigos, JD | 1 |
| Katsambas, A | 1 |
| Weise, L | 1 |
| Renger, F | 1 |
| Krebs, A | 1 |
| Steinbrück, P | 1 |
| Wosornu, D | 1 |
| MacIntyre, D | 1 |
| Watt, B | 1 |
| Ndiaye, IP | 1 |
| Ndiaye, MM | 1 |
| Mauferon, JB | 1 |
| Diagne, M | 1 |
| Diop, AG | 1 |
| Nardell, E | 1 |
| McInnis, B | 1 |
| Thomas, B | 1 |
| Weidhaas, S | 1 |
| Koriakin, VA | 1 |
| Grinchar, NA | 1 |
| Iurchenko, LN | 1 |
| Pantuck, EJ | 1 |
| Pantuck, CB | 1 |
| Ryan, DE | 1 |
| Conney, AH | 1 |
| Bammer, HG | 1 |
| Scheuer, PJ | 1 |
| Summerfield, JA | 1 |
| Lal, S | 1 |
| Sherlock, S | 2 |
| Levi, AJ | 1 |
| Walker, D | 1 |
| Stottmeier, KD | 1 |
| Burkes, J | 1 |
| Bleandonu, G | 1 |
| Boye, J | 1 |
| Clark, MA | 1 |
| Khogali, AM | 1 |
| Chazan, BI | 1 |
| Metcalf, VJ | 1 |
| Ramsay, JH | 1 |
| Sullivan, AL | 1 |
| Weintraub, LR | 1 |
| Brummer, DL | 1 |
| Kok-Jensen, A | 1 |
| Jarema, M | 1 |
| Korwin-Piotrowska, T | 1 |
| Christensen, O | 1 |
| Hyde, L | 1 |
| Woolpert, SF | 1 |
| Lavernhe, J | 1 |
| Tiitinen, H | 2 |
| Renier, JC | 1 |
| Oury, M | 1 |
| Bregeon, C | 1 |
| Tuchais, E | 1 |
| Onstad, GD | 1 |
| Sbarbaro, JA | 1 |
| Rotenberg, L | 1 |
| Sfikakis, P | 1 |
| Gottwald, W | 1 |
| Milne, RC | 1 |
| Wasik, A | 1 |
| Bruncsák, A | 1 |
| Timár, S | 1 |
| Cornea, P | 1 |
| Marcovici, G | 1 |
| Mainardi, L | 1 |
| Bissanti, A | 1 |
| Whittington, HG | 1 |
| Grey, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| URBAN ARCH (3/5) Uganda Cohort TB Preventive Therapy for HIV-infected Alcohol Users in Uganda: an Evaluation of Safety Tolerability and Adherence[NCT03302299] | Phase 4 | 302 participants (Actual) | Interventional | 2017-04-07 | Completed | ||
| Urinary Excretion of Acetylamantadine by Cancer Patients[NCT02277938] | 120 participants (Anticipated) | Observational | 2013-08-31 | Recruiting | |||
| Prophylactic Use of Entecavir to Reduce Hepatitis Flare in Highly Viremic HBV Patients With Active Tuberculosis Receiving Anti-tuberculous Treatment[NCT01724723] | Phase 4 | 50 participants (Anticipated) | Interventional | 2012-12-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Safety will be assessed by the occurrence of a Grade 3/4 hepatotoxicity at any time during the assigned treatment period. (NCT03302299)
Timeframe: Hepatotoxicity occurring during the six month course (180 pills) of isoniazid (INH), which may be taken over a maximum of 9 months.
| Intervention | percent (Number) |
|---|---|
| INH and Vitamin B6 | 8.3 |
Lack of tolerability will be defined as any isoniazid (INH) treatment discontinuation prior to completion of the prescribed course (6 months of INH taken over a maximum period of 9 months) due to side effects or alanine transaminase (ALT)/aspartate transaminase (AST) elevations. (NCT03302299)
Timeframe: Six month course (180 pills) of isoniazid (INH), which may be taken over a maximum of 9 months.
| Intervention | Participants (Count of Participants) |
|---|---|
| INH and Vitamin B6 | 32 |
Alanine transaminase (ALT) or aspartate transaminase (AST) elevations (>2x the upper limit of normal) at study screening (NCT03302299)
Timeframe: Study screening visit
| Intervention | Participants (Count of Participants) |
|---|---|
| Study Screening | 80 |
Latent tuberculosis assessed at screening via tuberculin skin testing (TST). A TST induration >=5mm was considered positive for latent tuberculosis. (NCT03302299)
Timeframe: Study screening visit
| Intervention | Participants (Count of Participants) |
|---|---|
| Study Screening | 308 |
INH concentration in hair (pmol/mg) will be measured at 3- and 6- months during INH therapy. (NCT03302299)
Timeframe: Measured at 3- and 6- months after INH initiation
| Intervention | pmol/mg (Median) | |
|---|---|---|
| at 3 months | at 6 months | |
| INH and Vitamin B6 | 36.0 | 37.8 |
Suboptimal INH adherence was defined as <90% of days with at least 1 electronic medication management (EMM) pill cap opening in the previous 90 days, at 3- and 6-months. (NCT03302299)
Timeframe: Adherence will be measured over the 6 months on INH or until INH discontinuation (whichever is shorter)
| Intervention | percentage of participants (Number) | |
|---|---|---|
| at 3 months | at 6 months | |
| INH and Vitamin B6 | 31.3 | 43.9 |
"Participants were asked In the past 30 days, how many days in total have you not taken your pill? and were presented with a visual analog scale (VAS) to indicate the percentage of INH taken in the past 30 days. We converted the VAS percentage into number of days out of 30 to match the first question. Our final self-report measure was the minimum number of the 2 self-reported measurements." (NCT03302299)
Timeframe: Self-reported INH medication adherence via VAS will be measured 3- and 6- months after starting INH
| Intervention | days (Median) | |
|---|---|---|
| at 3 months | at 6 months | |
| INH and Vitamin B6 | 30 | 30 |
The Self Rating Single Item (SRSI) adherence scale asks participants to rate their ability to take their medications as prescribed over the past 30 days. Participants reporting INH use in the prior 30 days at the 3- or 6-month interview are included here, and reported their INH adherence in the prior 30 days as excellent, very good, good, fair, poor, or very poor. (NCT03302299)
Timeframe: Self-reported INH medication adherence via SRSI will be measured 3- and 6- months after starting INH
| Intervention | Participants (Count of Participants) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| At 3 months72558043 | At 6 months72558043 | |||||||||||
| Excellent | Very good | Good | Fair | Poor | Very poor | |||||||
| INH and Vitamin B6 | 160 | |||||||||||
| INH and Vitamin B6 | 79 | |||||||||||
| INH and Vitamin B6 | 38 | |||||||||||
| INH and Vitamin B6 | 2 | |||||||||||
| INH and Vitamin B6 | 124 | |||||||||||
| INH and Vitamin B6 | 90 | |||||||||||
| INH and Vitamin B6 | 41 | |||||||||||
| INH and Vitamin B6 | 4 | |||||||||||
| INH and Vitamin B6 | 0 | |||||||||||
| INH and Vitamin B6 | 1 | |||||||||||
6 reviews available for isoniazid and Alcoholism
| Article | Year |
|---|---|
[Niacin deficiency disease(pellagra)].
Topics: Alcoholism; Dementia; Dermatitis; Diagnosis, Differential; Diarrhea; Humans; Isoniazid; Niacin; Pell | 2000 |
[Hepatitis-like liver disorders caused by infections, poisoning and drugs].
Topics: Alcoholism; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cytomegalovirus Infection | 1976 |
[Neurological aspects of the vitamin B complex].
Topics: Alcoholism; Anticonvulsants; Cyanides; Deficiency Diseases; Electroencephalography; Erythrocytes; Fo | 1972 |
Sideroblastic anemias. An approach to diagnosis and management.
Topics: Alcoholism; Anemia, Sideroblastic; Erythrocytes, Abnormal; Female; Folic Acid Deficiency; Genes; Hem | 1973 |
[Treatment of tuberculosis with streptomycin and isoniazide combined with either aminosalyl or rifampicin].
Topics: Alcoholism; Aminosalicylic Acids; Bilirubin; Drug Therapy, Combination; Humans; Isoniazid; Patient D | 1973 |
Preventive therapy of tuberculosis.
Topics: Adolescent; Adult; Alcoholism; BCG Vaccine; Chemical and Drug Induced Liver Injury; Child; Clinical | 1974 |
8 trials available for isoniazid and Alcoholism
| Article | Year |
|---|---|
Financial incentives for reduced alcohol use and increased isoniazid adherence during tuberculosis preventive therapy among people with HIV in Uganda: an open-label, factorial randomised controlled trial.
Topics: Adolescent; Adult; Alcoholism; Biomarkers; Ethanol; Female; HIV Infections; Humans; Isoniazid; Male; | 2023 |
Rifampin-isoniazid therapy of alcoholic and nonalcoholic tuberculous patients in a U.S. Public Health Service Cooperative Therapy Trial.
Topics: Alcoholism; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Clinical Trials as | 1980 |
Tuberculosis treated with rifampicin, ethambutol and isoniazid: Danish tuberculosis trial 1972-1974.
Topics: Adolescent; Adult; Aged; Alcoholism; Clinical Trials as Topic; Denmark; Drug Therapy, Combination; E | 1982 |
[Hepatoxic side-effects of rifampicin. A comparative clinical study].
Topics: Alanine Transaminase; Alcoholism; Alkaline Phosphatase; Aspartate Aminotransferases; Chemical and Dr | 1977 |
[A pilot and a controlled study of the influence of ethambutol on serum urate concentration and uric acid clearance (author's transl)].
Topics: Alcoholism; Body Weight; Creatinine; Ethambutol; Humans; Isoniazid; Rifampin; Streptomycin; Tubercul | 1979 |
Phenylbutazone and isoniazid metabolism in patients with liver disease in relation to previous drug therapy.
Topics: Acetylesterase; Acute Disease; Alcoholism; Alkaline Phosphatase; Aspartate Aminotransferases; Barbit | 1968 |
[Treatment of tuberculosis with streptomycin and isoniazide combined with either aminosalyl or rifampicin].
Topics: Alcoholism; Aminosalicylic Acids; Bilirubin; Drug Therapy, Combination; Humans; Isoniazid; Patient D | 1973 |
Preventive therapy of tuberculosis.
Topics: Adolescent; Adult; Alcoholism; BCG Vaccine; Chemical and Drug Induced Liver Injury; Child; Clinical | 1974 |
71 other studies available for isoniazid and Alcoholism
| Article | Year |
|---|---|
Unhealthy Alcohol Use Is Associated With Suboptimal Adherence to Isoniazid Preventive Therapy in Persons With HIV in Southwestern Uganda.
Topics: Alcohol Drinking; Alcoholism; Antitubercular Agents; Female; HIV Infections; Humans; Isoniazid; Male | 2022 |
Determinants of alcohol use among people living with HIV initiating isoniazid preventive therapy in Ethiopia.
Topics: Adult; Alcohol Drinking; Alcoholism; Antitubercular Agents; Catha; Cross-Sectional Studies; Ethiopia | 2019 |
Isoniazid Preventive Therapy for People With HIV Who Are Heavy Alcohol Drinkers in High TB-/HIV-Burden Countries: A Risk-Benefit Analysis.
Topics: Adult; Alcoholism; Anti-Retroviral Agents; Antitubercular Agents; Brazil; Chemoprevention; Female; H | 2018 |
A Painful Red Eye.
Topics: Alcoholism; Antitubercular Agents; Conjunctival Diseases; Ethambutol; Eye Pain; Glucocorticoids; Hum | 2018 |
Isoniazid induced convulsions at therapeutic dose in an alcoholic and smoker patient.
Topics: Adult; Alcoholism; Anticonvulsants; Antitubercular Agents; Humans; Isoniazid; Male; Pyridoxine; Risk | 2015 |
Therapeutic drug monitoring in the treatment of tuberculosis patients.
Topics: Adult; Aged; Alcoholism; Antibiotics, Antitubercular; Antitubercular Agents; Chromatography, High Pr | 2012 |
Lack of toxicity from concomitant directly observed disulfiram and isoniazid-containing therapy for active tuberculosis.
Topics: Alcohol Deterrents; Alcoholism; Antitubercular Agents; Directly Observed Therapy; Disulfiram; Drug T | 2002 |
Use of isoniazid for latent tuberculosis infection in a public health clinic.
Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Antitubercular Agents; Chemical and Drug Induced L | 2003 |
[An epidemic of epileptic seizures in a sanatorium environment; possible role of alcoholism and isoniazid].
Topics: Alcoholism; Epilepsy; Hospitals, Special; Humans; Isoniazid; Niacin; Nicotinic Acids; Tuberculosis; | 1955 |
[Three cases of alcoholic polyneuritis combined with pulmonary tuberculosis; favorable effect of isoniazid therapy on polyneuritis].
Topics: Alcoholic Neuropathy; Alcoholism; Humans; Isoniazid; Neuritis; Tuberculosis; Tuberculosis, Pulmonary | 1956 |
[Three cases of alcoholic polyneuritis combined with pulmonary tuberculosis; favorable effect of isoniazid therapy on polyneuritis].
Topics: Alcoholic Neuropathy; Alcoholism; Humans; Isoniazid; Neuritis; Tuberculosis; Tuberculosis, Pulmonary | 1956 |
[Three cases of alcoholic polyneuritis combined with pulmonary tuberculosis; favorable effect of isoniazid therapy on polyneuritis].
Topics: Alcoholic Neuropathy; Alcoholism; Humans; Isoniazid; Neuritis; Tuberculosis; Tuberculosis, Pulmonary | 1956 |
[Three cases of alcoholic polyneuritis combined with pulmonary tuberculosis; favorable effect of isoniazid therapy on polyneuritis].
Topics: Alcoholic Neuropathy; Alcoholism; Humans; Isoniazid; Neuritis; Tuberculosis; Tuberculosis, Pulmonary | 1956 |
[THERAPEUTIC RESULTS IN 180 ALCOHOLIC PATIENTS WITH PULMONARY TUBERCULOSIS].
Topics: Adrenocorticotropic Hormone; Alcoholism; Aminosalicylic Acid; Aminosalicylic Acids; Empyema; Empyema | 1963 |
[SIDE-EFFECTS IN TUBERCULOSIS TREATMENT WITH CLASSICAL ANTIBACTERIAL DRUGS].
Topics: Alcoholism; Anti-Bacterial Agents; Diarrhea; Drug Hypersensitivity; Feeding and Eating Disorders; He | 1963 |
[CLINICAL DATA ON CHRONIC RECURRENT PANCREATIC NECROSIS].
Topics: Alcoholism; Cycloserine; Isoniazid; Pancreatic Diseases; Pancreatitis; Pneumonectomy; Streptomycin; | 1964 |
[APROPOS OF ETHIONAMIDE JAUNDICE].
Topics: Alanine Transaminase; Alcoholism; Aminosalicylic Acid; Aminosalicylic Acids; Aspartate Aminotransfer | 1964 |
THE ACETYLATION OF ISONIAZID IN ALCOHOLICS.
Topics: Acetates; Acetylation; Alcoholics; Alcoholism; Genetics, Medical; Humans; Isoniazid; Metabolism; Pro | 1964 |
REACTIONS TO ANTITUBERCULOSIS DRUGS AMONG CHINESE IN HONG KONG.
Topics: Alcoholism; Alopecia; Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Asian People | 1964 |
SOME DIFFICULTIES IN THE TREATMENT OF TUBERCULOUS ALCOHOLICS.
Topics: Alcoholics; Alcoholism; Aminosalicylic Acid; Aminosalicylic Acids; Drug Therapy; Humans; Isoniazid; | 1965 |
[Alcoholism. Introduction of the principle of enzyme inhibition as an adjuvant in its therapy].
Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Alcoholism; Biochemical Phenomena; Humans; Isoniazi | 1960 |
Multiple Pappenheimer bodies.
Topics: Alcoholism; Antitubercular Agents; Emergencies; Erythrocyte Inclusions; Folic Acid Deficiency; Human | 2005 |
[Possibilities of using Nootropyl in the treatment of tuberculosis].
Topics: Adult; Alcoholism; Animals; Chemical and Drug Induced Liver Injury; Female; Hepatitis, Alcoholic; Hu | 1983 |
[Liver damage following antituberculous therapy].
Topics: Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Ethambutol; Fatty Liver; Humans; Isoniazi | 1982 |
The predictive value of the lymphocyte transformation test in isoniazid-associated hepatitis.
Topics: Adult; Alcoholism; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; F | 1982 |
Pulmonary disease due to Mycobacterium xenopi. Report of two cases.
Topics: Aged; Alcoholism; Drug Therapy, Combination; Ethambutol; Humans; Isoniazid; Male; Middle Aged; Mycob | 1982 |
Fever response of patients on therapy for pulmonary tuberculosis.
Topics: Alcoholism; Antitubercular Agents; Bacterial Infections; Drug Therapy, Combination; Ethambutol; Fema | 1981 |
Hepatotoxicity from isoniazid and rifampin in inner-city AIDS patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Alanine Transaminase; Alcoholism; Antitubercular Agent | 1995 |
Chronic ethanol intoxication induces differential effects on GABAA and NMDA receptor function in the rat brain.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo | 1993 |
[A health system that does not live up to expectations. A primary health care team attempt at an integrated approach to a case].
Topics: Alcoholism; Angina Pectoris; Antitubercular Agents; Diagnosis, Differential; Humans; Isoniazid; Live | 1996 |
Short-course therapy of pulmonary tuberculosis: doctor's compliance.
Topics: Adult; Alcoholism; Ambulatory Care; Antitubercular Agents; Clinical Competence; Drug Combinations; F | 1996 |
Chronic ethanol intoxication enhances [3H]CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum.
Topics: Adenosine; Alcoholism; Animals; Cerebellar Cortex; Cerebellum; Dose-Response Relationship, Drug; Eth | 1996 |
[Behavioral disorders after treatment with isoniazid].
Topics: Aging; Alcoholism; Antitubercular Agents; Behavior; Contraindications; Diabetes Mellitus; Female; Hu | 2001 |
Genetic aspects in the metabolism of drugs and environmental agents [proceedings].
Topics: Acetyltransferases; Alcoholism; Alleles; alpha 1-Antitrypsin Deficiency; Aryl Hydrocarbon Hydroxylas | 1978 |
Treatment of tuberculosis in alcoholic patients.
Topics: Alcoholism; Hospitalization; Humans; Isoniazid; Long-Term Care; Patient Compliance; Rifampin; Social | 1977 |
[Pharmacokinetics of isoniazid, PAS, and cycloserin in acute and chronic alcoholic intoxication (experimental study)].
Topics: Alcoholic Intoxication; Alcoholism; Aminosalicylic Acid; Aminosalicylic Acids; Animals; Cycloserine; | 1978 |
[Urinary xanthurenic acid levels].
Topics: Age Factors; Aged; Alcoholism; Arthritis, Rheumatoid; Child; Contraceptives, Oral; Diabetes Mellitus | 1978 |
Tuberculosis and alcoholism. A partial solution through detection.
Topics: Alabama; Alcoholism; Ethambutol; Female; Humans; Isoniazid; Male; Mass Screening; Streptomycin; Tube | 1978 |
Predisposing factors in hepatitis induced by isoniazid-rifampin treatment of tuberculosis.
Topics: Acetylation; Adult; Age Factors; Alanine Transaminase; Alcoholism; Aspartate Aminotransferases; Bili | 1978 |
Tuberculous peritonitis in Manitoba.
Topics: Adolescent; Adult; Alcoholism; Child; Diagnosis, Differential; Drug Therapy, Combination; Ethambutol | 1978 |
Modern medical management of pulmonary tuberculosis.
Topics: Alcoholism; Ethambutol; Fever; Humans; Isoniazid; Rifampin; Tuberculin Test; Tuberculosis, Pulmonary | 1977 |
Pellagra: a still existing disease.
Topics: Alcoholism; Diet; Fluorouracil; Humans; Intestinal Absorption; Isoniazid; Mercaptopurine; Nicotinic | 1977 |
[The frequency and form of manifestation of liver damage under INH therapy].
Topics: Alcoholism; Alkaline Phosphatase; Bilirubin; Cholestasis; Hepatomegaly; Humans; Isoniazid; Liver; Tr | 1976 |
An outbreak of isoniazid resistant tuberculosis in Glasgow 1981-1988.
Topics: Alcoholism; Cluster Analysis; Disease Outbreaks; Drug Resistance, Microbial; Female; Humans; Ill-Hou | 1990 |
[Etiological aspects of polyneuritis in Senegal].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcoholism; Charcot-Marie-Tooth Disease; Child; Diabetic | 1989 |
Exogenous reinfection with tuberculosis in a shelter for the homeless.
Topics: Adult; Alcoholism; Boston; Drug Resistance, Microbial; Housing; Humans; Ill-Housed Persons; Isoniazi | 1986 |
[Pharmacokinetics of isoniazid in patients with pulmonary tuberculosis and alcoholism].
Topics: Adult; Alcoholism; Humans; Isoniazid; Kinetics; Tuberculosis, Pulmonary | 1986 |
Inhibition and stimulation of enflurane metabolism in the rat following a single dose or chronic administration of ethanol.
Topics: Alcoholism; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylam | 1985 |
Initial treatment of tuberculosis with streptomycin and isoniazid combined with either aminosalyl or rifampicin.
Topics: Alcoholism; Aminosalicylic Acids; Bilirubin; Dihydrostreptomycin Sulfate; Humans; Isoniazid; Rifampi | 1973 |
Rifampicin hepatitis. A clinical and histological study.
Topics: Adult; Aged; Alcoholism; Biopsy; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; | 1974 |
Primary drug-resistant Mycobacterium tuberculosis isolated in Massachusetts in 1972.
Topics: Adolescent; Adult; Aged; Alcoholism; Aminosalicylic Acids; Antitubercular Agents; Drug Resistance, M | 1974 |
[Neuropsychiatric incidences in antitubercular treatment consisting of isoniazid or isoniazid and ethionamide (8 cases)].
Topics: Acidosis; Adult; Alcoholism; Ammonia; Avitaminosis; Carboxy-Lyases; Chromatography, Paper; Chromatog | 1969 |
Recent trends in tuberculosis care.
Topics: Aftercare; Alcoholism; Aminosalicylic Acids; Ethambutol; Hospitals, Special; Humans; Isoniazid; Occu | 1974 |
Hyperlipidaemia as a complication of rifampicin treatment.
Topics: Alanine Transaminase; Alcoholism; Aminosalicylic Acids; Aspartate Aminotransferases; Cholesterol; Ch | 1974 |
Pulmonary tuberculosis in well-treated alcoholics. Long-term prognosis regarding relapses compared with non-alcoholic patients.
Topics: Alcoholism; Aminosalicylic Acids; Follow-Up Studies; Humans; Isoniazid; Prognosis; Recurrence; Strep | 1972 |
Severe cardiac failure in a chronic alcoholic.
Topics: Alcoholism; Autopsy; Body Weight; Cardiomyopathies; Chronic Disease; Diabetes Complications; Diagnos | 1973 |
"Isoniazid and the alcoholic".
Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Humans; Isoniazid | 1973 |
[Status epilepticus in clinical records].
Topics: Adolescent; Adult; Aged; Alcoholism; Craniocerebral Trauma; Diagnosis, Differential; Epilepsy; Femal | 1973 |
Follow-up of positive cases of pulmonary tuberculosis diagnosed in 1957.
Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Aminosalicylic Acids; Female; Follow-Up Studies; H | 1968 |
Hypersensitivity reactions and liver toxicity attributed to isoniazid.
Topics: Alcoholism; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Hypersensitivi | 1972 |
[Pollution and aviation occupation].
Topics: Aerospace Medicine; Alcoholism; Circadian Rhythm; Fatigue; Humans; Isoniazid; Work | 1971 |
Isoniazid and ethionamide serum levels and inactivation in Finnish subjects.
Topics: Adolescent; Adult; Age Factors; Alcoholism; Ethionamide; Female; Finland; Humans; Injections, Intrav | 1969 |
Isoniazid inactivation status and the development of chronic tuberculosis.
Topics: Adolescent; Adult; Aged; Alcoholism; Chronic Disease; Female; Humans; Isoniazid; Male; Middle Aged; | 1969 |
[The algodystrophies caused by antituberculous chemotherapy. Study of 24 cases].
Topics: Age Factors; Alcoholism; Aminosalicylic Acids; Barbiturates; Drug Synergism; Ethionamide; Female; Hu | 1969 |
Posthospital chemotherapy of the unreliable patient.
Topics: Adult; Aged; Alcoholism; Ambulatory Care; Female; Follow-Up Studies; Humans; Isoniazid; Male; Middle | 1970 |
Isoniazid and alcohol.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Drug Synergism; Ethanol; Humans; Isoniazid; Male; Tubercu | 1970 |
[Adverse effects of drugs in tuberculous patients. Allergic reactions due to isoniazid and hydantoins or disulfiram].
Topics: Alcoholism; Disulfiram; Drug Hypersensitivity; Drug Synergism; Epilepsy; Humans; Hydantoins; Isoniaz | 1970 |
Alcoholism and tuberculosis in Victoria.
Topics: Adolescent; Adult; Age Factors; Aged; Alcoholism; Aminobenzoates; Australia; Child; Child, Preschool | 1970 |
Mental disorders caused by isonicotinic acid hydrazide (INH) in the course of treatment of pulmonary tuberculosis.
Topics: Affective Symptoms; Age Factors; Alcoholism; Central Nervous System Diseases; Delirium; Delusions; E | 1970 |
[On acute isoniazid poisoning on the basis of 2 successfully treated cases].
Topics: Adult; Alcoholism; Blood Transfusion; Brain; Brain Edema; Gastric Lavage; Glucose; Glutamates; Human | 1967 |
[Contribution on the relationship between tuberculosis and alcoholism. Experimental morphological study results].
Topics: Acid Phosphatase; Alcoholism; Alkaline Phosphatase; Animals; Antitubercular Agents; Bronchi; Ethanol | 1967 |
Vitamins of the B complex.
Topics: Aged; Alcoholism; Anemia, Hypochromic; Avitaminosis; Beriberi; Heart Failure; Humans; Isoniazid; Ner | 1968 |
[Various current findings in the problem of pellagra].
Topics: Alcoholism; Deficiency Diseases; Diet; Feeding Behavior; Hartnup Disease; Humans; Isoniazid; Isonico | 1968 |
Possible interaction between disulfiram and isoniazid.
Topics: Adult; Alcoholism; Brain; Brain Chemistry; Disulfiram; Dopamine; Drug Synergism; Humans; Isoniazid; | 1969 |